Overview

ID MAG04035
Name TLS3_bin.11
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Burkholderiaceae
Genus JAOUJD01
Species
Assembly information
Completeness (%) 64.97
Contamination (%) 0.74
GC content (%) 70.0
N50 (bp) 4,641
Genome size (bp) 2,211,056

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2355

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1006392_0 RNA polymerase sigma factor RpoH K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 394.0
TLS3_k127_1006392_1 cell division K09812 - - 0.0000000000000000000000000000000000000000000000000000861 196.0
TLS3_k127_1006392_2 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000008139 99.0
TLS3_k127_1006392_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000006119 60.0
TLS3_k127_1011640_0 Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers K07518 - 3.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 586.0
TLS3_k127_1011640_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 544.0
TLS3_k127_1011640_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 496.0
TLS3_k127_1011640_3 - - - - 0.0000000000003495 83.0
TLS3_k127_1014250_0 DNA polymerase K02337 - 2.7.7.7 5.725e-210 669.0
TLS3_k127_1014250_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 534.0
TLS3_k127_1014250_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 321.0
TLS3_k127_1014250_3 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 296.0
TLS3_k127_1014250_4 N-terminal domain of galactosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002995 288.0
TLS3_k127_1014250_5 family 9 K02849 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005055 283.0
TLS3_k127_1014250_6 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002322 269.0
TLS3_k127_1014250_7 O-Antigen ligase - - - 0.0000000000000000000000000000001219 144.0
TLS3_k127_101466_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.589e-316 980.0
TLS3_k127_101466_1 - - - - 0.000000008755 60.0
TLS3_k127_1024258_0 Pilus retraction K02669,K12203 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 598.0
TLS3_k127_1024258_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 309.0
TLS3_k127_1024258_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000149 289.0
TLS3_k127_1024258_3 Type II/IV secretion system protein K02670 - - 0.0000000000000000000000000000000000000000000004939 170.0
TLS3_k127_1024258_4 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000002043 95.0
TLS3_k127_1024258_5 - - - - 0.000000007655 64.0
TLS3_k127_1028434_0 Transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1385.0
TLS3_k127_1028434_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.426e-212 667.0
TLS3_k127_1028434_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 392.0
TLS3_k127_1028434_3 - - - - 0.0000000000000000000000000000000000000006027 160.0
TLS3_k127_1028434_4 PFAM CopG domain protein DNA-binding domain protein - - - 0.00000000000000000008496 91.0
TLS3_k127_103011_0 Tartrate dehydrogenase K07246 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 581.0
TLS3_k127_103011_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 359.0
TLS3_k127_103011_2 PFAM thioesterase superfamily protein K07107 - - 0.0000000000000000000000000000000000000000000000000000000000002968 224.0
TLS3_k127_103011_3 Drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000002645 214.0
TLS3_k127_1035831_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 411.0
TLS3_k127_1035831_1 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 370.0
TLS3_k127_1035831_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008341 353.0
TLS3_k127_1035831_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006346 337.0
TLS3_k127_1035831_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 337.0
TLS3_k127_1035831_5 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000001475 234.0
TLS3_k127_1035831_6 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000001392 147.0
TLS3_k127_1035831_7 Domain of unknown function (DUF4845) - - - 0.00000000000000000000006465 103.0
TLS3_k127_10454_0 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 378.0
TLS3_k127_10454_1 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000001908 145.0
TLS3_k127_1052970_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 2.164e-253 789.0
TLS3_k127_1052970_1 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 359.0
TLS3_k127_1053881_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 9.448e-252 782.0
TLS3_k127_1053881_1 Heavy-metal-associated domain K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 541.0
TLS3_k127_1053881_2 Cytochrome oxidase maturation protein - - - 0.00006564 55.0
TLS3_k127_1063180_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 508.0
TLS3_k127_1063180_1 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 394.0
TLS3_k127_1063180_2 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 387.0
TLS3_k127_1065970_0 Protein of unknown function (DUF4080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 293.0
TLS3_k127_1065970_1 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000006544 187.0
TLS3_k127_1065970_2 ketosteroid isomerase - - - 0.0000000000000000002463 94.0
TLS3_k127_1074009_0 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.0 1079.0
TLS3_k127_1074009_1 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 313.0
TLS3_k127_1074009_2 PFAM amidohydrolase 2 K07045 - - 0.000000000000000000000000000000000000000000000000000000000000005774 220.0
TLS3_k127_1081585_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1103.0
TLS3_k127_1081585_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 356.0
TLS3_k127_1081585_2 CYTH K01768 - 4.6.1.1 0.0000000000000000000000000004696 117.0
TLS3_k127_109754_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1565.0
TLS3_k127_109754_1 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 575.0
TLS3_k127_109754_2 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.00000000000000000000000000000000000000000000000000000000001344 222.0
TLS3_k127_1111848_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 427.0
TLS3_k127_1111848_1 Sigma-54 interaction domain K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001868 276.0
TLS3_k127_1111848_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000001778 248.0
TLS3_k127_1112989_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008809 441.0
TLS3_k127_1112989_1 Short-chain dehydrogenase reductase (SDR) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000001143 204.0
TLS3_k127_1112989_2 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000001474 138.0
TLS3_k127_1114678_0 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004031 231.0
TLS3_k127_1114678_1 - - - - 0.0000000000000000000000000006919 118.0
TLS3_k127_1114678_2 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000002377 104.0
TLS3_k127_1115295_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 450.0
TLS3_k127_1115295_1 PIN domain - - - 0.000000000000000000000001878 108.0
TLS3_k127_1115295_2 - - - - 0.0000000000000009667 78.0
TLS3_k127_1116775_0 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 321.0
TLS3_k127_1116775_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002334 276.0
TLS3_k127_1116775_2 Preprotein translocase SecG subunit K03075 - - 0.0000002018 53.0
TLS3_k127_1123137_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 451.0
TLS3_k127_1123137_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000772 301.0
TLS3_k127_1123137_2 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001548 275.0
TLS3_k127_1123137_3 protein conserved in bacteria K09966 - - 0.000000000000000000000000000000000000000000000000001556 186.0
TLS3_k127_1123137_4 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000168 168.0
TLS3_k127_1123137_5 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000000002178 99.0
TLS3_k127_1124955_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008064 469.0
TLS3_k127_1124955_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 392.0
TLS3_k127_1128908_0 COG0524 Sugar kinases, ribokinase family K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 397.0
TLS3_k127_1128908_1 Protein of unknown function (DUF3426) - - - 0.00000000000000000000001 112.0
TLS3_k127_1136924_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.826e-273 849.0
TLS3_k127_1136924_1 Bacterial transcriptional repressor C-terminal K16137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001218 263.0
TLS3_k127_1136924_2 Bacterial-like globin - - - 0.000000000000000000000000000000000000004175 160.0
TLS3_k127_1136924_3 methyltransferase activity - - - 0.00000000000000000000000000000000000002879 153.0
TLS3_k127_1136924_4 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000013 142.0
TLS3_k127_1136924_5 Domain of unknown function (DUF1850) - - - 0.000000000000000000000000000000003979 148.0
TLS3_k127_1143629_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 529.0
TLS3_k127_1143629_1 O-Antigen ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 341.0
TLS3_k127_1143629_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000004526 189.0
TLS3_k127_1143629_3 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000003844 144.0
TLS3_k127_1143629_4 TPR repeat - - - 0.00000000000000003835 82.0
TLS3_k127_1147003_0 HI0933 family K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 500.0
TLS3_k127_1147003_1 4-carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000000007106 208.0
TLS3_k127_1147003_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000005059 191.0
TLS3_k127_1147003_3 - - - - 0.000000000000000000000000000000000004848 139.0
TLS3_k127_1150333_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 311.0
TLS3_k127_1150333_1 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000000000009121 189.0
TLS3_k127_1150333_2 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000003451 164.0
TLS3_k127_1154629_0 Pyridoxal-phosphate dependent enzyme K01505,K05396,K17950 - 3.5.99.7,4.4.1.15,4.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 502.0
TLS3_k127_1154629_1 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 404.0
TLS3_k127_1154629_2 LUD domain K00782 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002602 273.0
TLS3_k127_1154629_3 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000002632 243.0
TLS3_k127_1154629_4 Putative citrate transport - - - 0.00000000000000000000000000000000000000000005498 165.0
TLS3_k127_1154629_5 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 0.000000000000000000000000003367 110.0
TLS3_k127_1156527_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001086 286.0
TLS3_k127_1156527_1 PFAM TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002709 256.0
TLS3_k127_1156527_2 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000001497 237.0
TLS3_k127_1156527_3 Histidine kinase - - - 0.0000000000000000000000000055 122.0
TLS3_k127_1168219_0 ABC transporter transmembrane region K06147 - - 5.849e-256 802.0
TLS3_k127_1168219_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001238 279.0
TLS3_k127_1168219_2 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000000000000000000000000001212 198.0
TLS3_k127_1168219_3 FAD dependent oxidoreductase K00244 - 1.3.5.4 0.0000000000000000000000000000000000000001149 156.0
TLS3_k127_1168219_4 Bacterial periplasmic substrate-binding proteins K10001 - - 0.0000000000000000000000000000000000001041 145.0
TLS3_k127_1168722_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 595.0
TLS3_k127_1168722_1 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 377.0
TLS3_k127_1168722_2 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000001708 144.0
TLS3_k127_1184686_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.57e-254 811.0
TLS3_k127_1184686_1 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000000005608 145.0
TLS3_k127_1184686_2 MerR, DNA binding - - - 0.0000000000000000000000000000000004276 137.0
TLS3_k127_11971_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 595.0
TLS3_k127_11971_1 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006874 370.0
TLS3_k127_11971_2 Putative nucleotide-binding of sugar-metabolising enzyme K21948 - 2.7.1.217 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 305.0
TLS3_k127_11971_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009803 303.0
TLS3_k127_11971_4 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000000000005502 210.0
TLS3_k127_11971_5 cell division protein - - - 0.00000000000000000000000000000005876 132.0
TLS3_k127_1218450_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 9.863e-310 960.0
TLS3_k127_1218450_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 384.0
TLS3_k127_1218450_2 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 394.0
TLS3_k127_1218450_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006431 279.0
TLS3_k127_1218450_4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000002507 263.0
TLS3_k127_1218450_5 oxidoreductase DsbE K02199 - - 0.000000000000000000000000000000000000000000000000000000000000000000004693 246.0
TLS3_k127_1218450_6 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000000000003953 219.0
TLS3_k127_1218450_7 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000004223 147.0
TLS3_k127_1218450_8 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.00000001223 57.0
TLS3_k127_123400_0 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000002514 158.0
TLS3_k127_123400_1 PGAP1-like protein - - - 0.00000000000000000000000000000000000000005341 165.0
TLS3_k127_123400_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000005821 127.0
TLS3_k127_1248627_0 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 582.0
TLS3_k127_1248627_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 307.0
TLS3_k127_1248627_2 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000000000000000000000000000000000003383 196.0
TLS3_k127_1248627_3 across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro Biopolymer transport protein ExbD TolR Pfam Biopolymer transport protein ExbD TolR no signal peptide K03559 - - 0.0000000000000000000000000000000000000000000000003781 178.0
TLS3_k127_1271850_0 Permease YjgP YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 349.0
TLS3_k127_1271850_1 Permease YjgP YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 357.0
TLS3_k127_1271850_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.00000000000000000000000003918 125.0
TLS3_k127_1298963_0 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000004996 217.0
TLS3_k127_1298963_1 Protein of unknown function (DUF4236) - - - 0.0000000000000000000002075 110.0
TLS3_k127_1298963_2 Protein of unknown function (DUF4236) - - - 0.0004015 52.0
TLS3_k127_130321_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 550.0
TLS3_k127_130321_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 334.0
TLS3_k127_130321_2 negative regulator of sigma E activity K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000005023 241.0
TLS3_k127_130321_3 PFAM Anti sigma-E protein RseA K03597 - - 0.0000000000437 71.0
TLS3_k127_130321_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000916 63.0
TLS3_k127_1305162_0 FAD linked oxidase domain protein - - - 0.0 2025.0
TLS3_k127_1305162_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 501.0
TLS3_k127_1305162_2 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 493.0
TLS3_k127_1305162_3 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000387 168.0
TLS3_k127_1305162_4 HIT domain - - - 0.0000000000000000000000000000000000000001161 167.0
TLS3_k127_1313950_0 Isochorismatase hydrolase - - - 0.000000000000000000000000000000000000000004523 162.0
TLS3_k127_1313950_1 MaoC like domain - - - 0.0000000000000000000000000000002565 134.0
TLS3_k127_1313950_2 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.0000000000002777 70.0
TLS3_k127_133112_0 Protein of unknown function - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 522.0
TLS3_k127_133112_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000002436 141.0
TLS3_k127_1336895_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 444.0
TLS3_k127_1336895_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 434.0
TLS3_k127_1336895_2 malonyl CoA-acyl carrier protein transacylase K00645,K15355 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 419.0
TLS3_k127_1336895_3 reductase K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 334.0
TLS3_k127_1336895_4 Ribosomal L32p protein family K02911 - - 0.0000000000000000000000000004656 118.0
TLS3_k127_1336895_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000001553 100.0
TLS3_k127_1336895_6 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.000009178 50.0
TLS3_k127_1384410_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 501.0
TLS3_k127_1384410_1 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.000000000000000000000000000000000000000000000001018 198.0
TLS3_k127_1410145_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 369.0
TLS3_k127_1410145_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000807 231.0
TLS3_k127_1418479_0 Electron transfer flavoprotein domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 455.0
TLS3_k127_1418479_1 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 357.0
TLS3_k127_1418479_2 HI0933-like protein K00313 - - 0.000000000000000000000000000000000000000000000001225 178.0
TLS3_k127_1419039_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008368 602.0
TLS3_k127_1419039_1 Protein of unknown function (DUF455) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 329.0
TLS3_k127_1419039_2 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003549 267.0
TLS3_k127_1419039_3 COG2185 Methylmalonyl-CoA mutase, C-terminal domain subunit (cobalamin-binding) K01849,K20907 - 5.4.99.2,5.4.99.64 0.000000000000000000000000000000000000000000000000000000000000000000309 234.0
TLS3_k127_1420521_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 1.387e-208 664.0
TLS3_k127_1420521_1 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001637 270.0
TLS3_k127_1420521_2 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000002433 217.0
TLS3_k127_1420521_3 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000000002217 213.0
TLS3_k127_1420521_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000004531 150.0
TLS3_k127_1428966_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 2.789e-222 700.0
TLS3_k127_1428966_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 442.0
TLS3_k127_1428966_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000009597 111.0
TLS3_k127_1446557_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 510.0
TLS3_k127_1446557_1 Bacterial transcriptional activator domain - - - 0.000006637 57.0
TLS3_k127_1463548_0 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 539.0
TLS3_k127_1463548_1 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001465 254.0
TLS3_k127_1463548_2 GXGXG motif K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.000000000000000000000000000000000000000000000000000006927 192.0
TLS3_k127_1463548_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000003897 149.0
TLS3_k127_1592270_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 381.0
TLS3_k127_1592270_1 Transcriptional regulator K21747 - - 0.0000000000000000000000000000000000000000000000000000000000000000002994 242.0
TLS3_k127_1629616_0 Ni,Fe-hydrogenase I large subunit - - - 0.00000000000000000000000000000000000000000000000000003538 207.0
TLS3_k127_1629616_1 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.0000000000000000000000000000000298 135.0
TLS3_k127_1629616_2 Belongs to the rubredoxin family - - - 0.0000000000000000000000001692 109.0
TLS3_k127_1629616_3 PFAM HupH hydrogenase expression protein K03618 - - 0.000000000000000496 78.0
TLS3_k127_168430_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 3.828e-277 862.0
TLS3_k127_168430_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 3.647e-205 653.0
TLS3_k127_168430_2 Sigma-54 interaction domain K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 548.0
TLS3_k127_168430_3 His Kinase A (phosphoacceptor) domain K02668,K10125 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 345.0
TLS3_k127_168430_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 310.0
TLS3_k127_168430_5 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 294.0
TLS3_k127_168430_6 Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005862 252.0
TLS3_k127_168430_7 Negative regulator of beta-lactamase expression K01447,K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043170,GO:0044424,GO:0044464,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000001139 237.0
TLS3_k127_168430_8 PFAM Lytic transglycosylase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000001791 245.0
TLS3_k127_168430_9 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0000000000000000000000000000000000000002032 157.0
TLS3_k127_1687593_0 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 498.0
TLS3_k127_1687593_1 DoxX-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 339.0
TLS3_k127_1687593_2 - - - - 0.0000000000000000000000000000000000000003257 156.0
TLS3_k127_1687593_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000001747 74.0
TLS3_k127_1720914_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 446.0
TLS3_k127_1720914_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000001513 96.0
TLS3_k127_1721210_0 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 351.0
TLS3_k127_1721210_1 Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000000000000000000000000000000000003039 238.0
TLS3_k127_1721210_2 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000001128 180.0
TLS3_k127_1721210_3 YbaK prolyl-tRNA synthetase associated - - - 0.000000000000000000000000000000000000000003603 160.0
TLS3_k127_1721210_4 MarC family integral membrane protein K05595 - - 0.0000000001282 70.0
TLS3_k127_1721221_0 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 351.0
TLS3_k127_1721221_1 Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000000000000000000000000000000000001067 240.0
TLS3_k127_1721221_2 UPF0056 inner membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000001493 216.0
TLS3_k127_1721221_3 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000001128 180.0
TLS3_k127_1721221_4 RNB K01147 - 3.1.13.1 0.0000000000000000000000000000000000000000000000006761 188.0
TLS3_k127_1721221_5 YbaK prolyl-tRNA synthetase associated - - - 0.0000000000000000000000000000000000000000003969 162.0
TLS3_k127_1729854_0 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03669 - - 1.809e-239 754.0
TLS3_k127_173510_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 512.0
TLS3_k127_173510_1 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000154 154.0
TLS3_k127_173510_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.000000007796 57.0
TLS3_k127_1750772_0 transcriptional regulator - - - 0.000000000000000000000000000000000001153 150.0
TLS3_k127_1750772_1 Tellurite resistance protein TerB - - - 0.00000000000000001501 87.0
TLS3_k127_1750772_2 - - - - 0.0001715 53.0
TLS3_k127_1762093_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 537.0
TLS3_k127_1762093_1 NADH flavin oxidoreductase NADH oxidase K00219,K09461 - 1.14.13.40,1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 520.0
TLS3_k127_1762093_10 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000001561 224.0
TLS3_k127_1762093_11 Phosphoglycerate mutase K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000007575 214.0
TLS3_k127_1762093_12 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000000000008071 194.0
TLS3_k127_1762093_13 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000004316 204.0
TLS3_k127_1762093_14 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000005665 174.0
TLS3_k127_1762093_15 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000001017 117.0
TLS3_k127_1762093_16 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000002366 114.0
TLS3_k127_1762093_17 CAAX protease self-immunity K07052 - - 0.000000001208 68.0
TLS3_k127_1762093_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 521.0
TLS3_k127_1762093_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 481.0
TLS3_k127_1762093_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 475.0
TLS3_k127_1762093_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 354.0
TLS3_k127_1762093_6 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 346.0
TLS3_k127_1762093_7 phospholipid-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 317.0
TLS3_k127_1762093_8 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 285.0
TLS3_k127_1762093_9 riboflavin synthase, alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000003494 255.0
TLS3_k127_1765088_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.712e-298 929.0
TLS3_k127_1765088_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 1.268e-206 654.0
TLS3_k127_1765088_2 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 505.0
TLS3_k127_1765088_3 acid dehydrogenase K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000004825 228.0
TLS3_k127_1777033_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 305.0
TLS3_k127_1777033_1 SCP-2 sterol transfer family K03690 - - 0.0000000000000000000000000000000003001 140.0
TLS3_k127_1777033_2 import inner membrane translocase, subunit Tim44 - - - 0.0000000000000000000000000001148 117.0
TLS3_k127_1777291_0 aldo keto reductase K19265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 344.0
TLS3_k127_1777291_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000006452 249.0
TLS3_k127_1777291_2 Peptidase family M23 K21472 - - 0.00000000000000000000000000000000000000000000000000002076 193.0
TLS3_k127_1777291_3 - - - - 0.00000000000000000001082 99.0
TLS3_k127_1782251_0 SNARE associated Golgi protein - - - 3.047e-286 894.0
TLS3_k127_1782410_0 PA domain - - - 0.0 1095.0
TLS3_k127_1782410_1 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000007067 163.0
TLS3_k127_1788508_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 527.0
TLS3_k127_1788508_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 445.0
TLS3_k127_1788508_2 PFAM L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 356.0
TLS3_k127_1788508_3 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008442 265.0
TLS3_k127_1788508_4 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000008602 217.0
TLS3_k127_1788508_5 Protein of unknown function (DUF3833) - - - 0.00000000000000000000000000000000000000000000000000001645 195.0
TLS3_k127_1788508_6 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000007147 190.0
TLS3_k127_1788508_7 SnoaL-like domain K01822 - 5.3.3.1 0.000000000000000000000000000000000000000000005873 178.0
TLS3_k127_1788508_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000002335 131.0
TLS3_k127_1791712_0 oxidoreductase K04090 - 1.2.7.8 0.0 1637.0
TLS3_k127_1791712_1 Peptidase family M3 K01284 - 3.4.15.5 7.676e-265 842.0
TLS3_k127_1791712_10 General Secretory Pathway K02463 - - 0.0000000000000000000000000000000000002462 150.0
TLS3_k127_1791712_11 - - - - 0.00000000000000000000000000000007053 134.0
TLS3_k127_1791712_12 involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000000000000000000000573 128.0
TLS3_k127_1791712_13 Protein of unknown function (DUF3108) - - - 0.0000000000000000002691 101.0
TLS3_k127_1791712_14 General secretion pathway K02462 - - 0.00000000000000001795 90.0
TLS3_k127_1791712_2 type II secretion system protein E K02454 - - 1.082e-212 670.0
TLS3_k127_1791712_3 general secretion pathway protein D K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 631.0
TLS3_k127_1791712_4 fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 526.0
TLS3_k127_1791712_5 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 480.0
TLS3_k127_1791712_6 General secretion pathway protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 443.0
TLS3_k127_1791712_7 B12 binding domain K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 310.0
TLS3_k127_1791712_8 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005605 312.0
TLS3_k127_1791712_9 membrane - - - 0.0000000000000000000000000000000000000000009477 180.0
TLS3_k127_1793170_0 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 400.0
TLS3_k127_1793170_1 cytochrome C oxidase K02258 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007522 244.0
TLS3_k127_1793170_2 signal sequence binding - - - 0.00000000000000000000000000000000000000000000000000006427 202.0
TLS3_k127_1793170_3 SURF1-like protein K14998 - - 0.000000000000000000000000000000000000000000001236 186.0
TLS3_k127_1793170_4 cytochrome oxidase assembly K02259 - - 0.0000000000000000229 92.0
TLS3_k127_1793170_5 Protein of unknown function (DUF2909) - - - 0.00000000000000002797 92.0
TLS3_k127_1793170_6 Protein of unknown function (DUF2970) - - - 0.0000000000000002263 87.0
TLS3_k127_1806917_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 8.216e-290 902.0
TLS3_k127_1806917_1 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 517.0
TLS3_k127_1806917_2 HlyD family secretion protein K13408 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004309 276.0
TLS3_k127_1806917_3 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000003756 221.0
TLS3_k127_1806917_4 Ferredoxin K04755 - - 0.00000000000000000000000000000000000000000000000002904 180.0
TLS3_k127_1806917_5 oligoketide cyclase lipid transport protein - - - 0.0000000000000000000000000000000000000000000002852 171.0
TLS3_k127_1806917_6 Exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000001481 166.0
TLS3_k127_1806917_7 Domain of unknown function (DUF4124) - - - 0.00000000000000000001036 98.0
TLS3_k127_1806917_8 Fe-S assembly protein IscX - - - 0.00000000000000000002468 106.0
TLS3_k127_1806917_9 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000000002238 87.0
TLS3_k127_1810169_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 471.0
TLS3_k127_1810169_1 Domain of unknown function (DUF3473) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 350.0
TLS3_k127_1810533_0 COG0841 Cation multidrug efflux pump K03296,K18138 - - 2.098e-263 824.0
TLS3_k127_1828313_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 480.0
TLS3_k127_1828313_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 397.0
TLS3_k127_1828313_2 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000000000002068 162.0
TLS3_k127_1828313_3 Copper binding periplasmic protein CusF - - - 0.000000000000000002989 89.0
TLS3_k127_1828909_0 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 426.0
TLS3_k127_1828909_1 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000385 271.0
TLS3_k127_1829275_0 Hydroxymethylglutaryl-CoA lyase K01640 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 453.0
TLS3_k127_1829275_1 d-isomer specific 2-hydroxyacid dehydrogenase, nad-binding K12972 - 1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 297.0
TLS3_k127_1829275_2 type IV pilus modification protein PilV - - - 0.00000000000000000000000000000001404 135.0
TLS3_k127_1829275_3 type 4 fimbrial biogenesis K02672 - - 0.000000000000000000000000000002231 132.0
TLS3_k127_1829275_4 pilus assembly protein PilE K02655 - - 0.0000000000000000000001156 106.0
TLS3_k127_1829275_5 Type II transport protein GspH K08084 - - 0.00000000000000000003633 98.0
TLS3_k127_1829275_6 carboxylase K01965,K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.3,6.4.1.4 0.0000000000000004077 78.0
TLS3_k127_1834497_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.819e-282 886.0
TLS3_k127_1834497_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 439.0
TLS3_k127_1834497_10 - - - - 0.000000006526 65.0
TLS3_k127_1834497_2 DsrE/DsrF-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000557 276.0
TLS3_k127_1834497_3 PepSY-associated TM helix - - - 0.0000000000000000000000000000000000000000000005513 181.0
TLS3_k127_1834497_4 Bacterial regulatory proteins, tetR family K16137 - - 0.00000000000000000000000000000000000002971 150.0
TLS3_k127_1834497_5 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000007713 142.0
TLS3_k127_1834497_6 Protein of unknown function (DUF3297) - - - 0.000000000000000000000000000000131 126.0
TLS3_k127_1834497_7 Rhodanese-related sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000002443 138.0
TLS3_k127_1834497_8 Transmembrane secretion effector - - - 0.0000000000000000000003453 110.0
TLS3_k127_1834497_9 Acetyltransferase (GNAT) domain - - - 0.00000000001302 78.0
TLS3_k127_1843483_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 456.0
TLS3_k127_1843483_1 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000003227 223.0
TLS3_k127_1843483_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000001478 132.0
TLS3_k127_1848764_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 563.0
TLS3_k127_1848764_1 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 304.0
TLS3_k127_1848764_2 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000001178 223.0
TLS3_k127_1848764_3 Putative member of DMT superfamily (DUF486) K09922 - - 0.000000000000000000000000000000000000000000000000000001619 196.0
TLS3_k127_1848764_4 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000696 161.0
TLS3_k127_1849633_0 Glucose / Sorbosone dehydrogenase - - - 5.08e-203 642.0
TLS3_k127_1849633_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 501.0
TLS3_k127_1849633_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000003143 233.0
TLS3_k127_1849633_3 membrane - - - 0.000000000000000000000000000000000316 136.0
TLS3_k127_1852134_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 474.0
TLS3_k127_1852134_1 transposase IS116 IS110 IS902 family - - - 0.0000000000000000000000000000000593 134.0
TLS3_k127_1901279_0 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 532.0
TLS3_k127_1901279_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 508.0
TLS3_k127_1901279_2 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 481.0
TLS3_k127_1901279_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 447.0
TLS3_k127_1901279_4 Glucose sorbosone K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 321.0
TLS3_k127_1912520_0 Zn-dependent protease with chaperone function - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 308.0
TLS3_k127_1912520_1 Nucleoside H+ symporter K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006402 293.0
TLS3_k127_1912520_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000004133 227.0
TLS3_k127_1912520_3 Dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000001726 167.0
TLS3_k127_1912520_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000002029 92.0
TLS3_k127_1917306_0 Transcriptional regulatory protein, C terminal K02483,K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 400.0
TLS3_k127_1917306_1 histidine kinase HAMP region domain protein K07638 - 2.7.13.3 0.00000007156 57.0
TLS3_k127_1924326_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000534 241.0
TLS3_k127_1924326_1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02351 - - 0.00000000000000000000000000000000000000000000000000000000001456 214.0
TLS3_k127_1924326_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000002035 79.0
TLS3_k127_1924326_3 - - - - 0.0000000199 61.0
TLS3_k127_1924326_4 Uncharacterised protein family (UPF0093) - - - 0.0007228 51.0
TLS3_k127_193118_0 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 410.0
TLS3_k127_193118_1 Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 321.0
TLS3_k127_193118_2 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 295.0
TLS3_k127_193118_3 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001539 242.0
TLS3_k127_194190_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 596.0
TLS3_k127_194190_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 449.0
TLS3_k127_194190_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000002218 121.0
TLS3_k127_1949998_0 LUD domain K18929 - - 2.227e-229 719.0
TLS3_k127_1949998_1 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003552 270.0
TLS3_k127_1949998_2 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000002653 201.0
TLS3_k127_1949998_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975,K03743 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008081,GO:0008104,GO:0008150,GO:0008452,GO:0008664,GO:0009966,GO:0010646,GO:0010738,GO:0016787,GO:0016788,GO:0016874,GO:0016886,GO:0023051,GO:0033036,GO:0034237,GO:0042578,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:0140098,GO:1902531 3.1.4.58,3.5.1.42 0.000001297 52.0
TLS3_k127_1949998_4 Domain of unknown function (DUF3597) - - - 0.00003862 53.0
TLS3_k127_195162_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.069e-216 678.0
TLS3_k127_195162_1 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 331.0
TLS3_k127_195162_2 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009875 279.0
TLS3_k127_195162_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 0.000000000000000000000000000000000000005851 150.0
TLS3_k127_1954191_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 474.0
TLS3_k127_1954191_1 Type IV fimbrial biogenesis protein PilY1 K02674 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 367.0
TLS3_k127_1954191_2 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.00000000000000000008398 99.0
TLS3_k127_1961912_0 Participates in both transcription termination and antitermination K02600 - - 3.749e-217 689.0
TLS3_k127_1961912_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 371.0
TLS3_k127_1961912_2 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000006044 165.0
TLS3_k127_1961912_3 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000002712 149.0
TLS3_k127_1971218_0 L-serine dehydratase K01752 - 4.3.1.17 7.091e-218 688.0
TLS3_k127_1971218_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 467.0
TLS3_k127_1971218_2 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000000000009088 217.0
TLS3_k127_1971218_3 Prolyl oligopeptidase family K06889 - - 0.00000000000000000000000000000000000000000000000000006055 212.0
TLS3_k127_1971218_4 Belongs to the small heat shock protein (HSP20) family - - - 0.000000004847 57.0
TLS3_k127_1985226_0 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 366.0
TLS3_k127_1985226_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000009177 264.0
TLS3_k127_1985226_2 Bacterial transcriptional regulator - - - 0.0000000000000000000000002274 109.0
TLS3_k127_1985226_3 LysR substrate binding domain - - - 0.00000000000000002308 87.0
TLS3_k127_2003580_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 3.803e-314 973.0
TLS3_k127_2003580_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 3.89e-229 719.0
TLS3_k127_2003580_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 571.0
TLS3_k127_2003580_3 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 458.0
TLS3_k127_2003580_4 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009961 332.0
TLS3_k127_2003580_5 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 284.0
TLS3_k127_2005818_0 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 580.0
TLS3_k127_2005818_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007827 321.0
TLS3_k127_2011877_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1405.0
TLS3_k127_2011877_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 395.0
TLS3_k127_2011877_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000005433 242.0
TLS3_k127_2011877_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000001489 125.0
TLS3_k127_2012319_0 - - - - 0.0000000007117 70.0
TLS3_k127_2012319_1 phage envelope protein - - - 0.0006739 50.0
TLS3_k127_2027286_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1073.0
TLS3_k127_2027286_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.944e-252 790.0
TLS3_k127_2027286_10 - - - - 0.0000000000005603 81.0
TLS3_k127_2027286_2 hydroxypyruvate reductase K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 519.0
TLS3_k127_2027286_3 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 526.0
TLS3_k127_2027286_4 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 485.0
TLS3_k127_2027286_5 Nad-dependent epimerase dehydratase K22025 - 1.1.1.410 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 356.0
TLS3_k127_2027286_6 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 325.0
TLS3_k127_2027286_7 Protein of unknown function (DUF3025) - - - 0.00000000000000000000000000000000000000000000000000000000006972 221.0
TLS3_k127_2027286_8 response regulator, receiver K03413 - - 0.000000000000000000000000000000003487 138.0
TLS3_k127_2027286_9 Cobalt uptake substrate-specific transmembrane region - - - 0.00000000000000000000004825 110.0
TLS3_k127_2032075_0 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 374.0
TLS3_k127_2032075_1 Type IV leader peptidase family K02278 - 3.4.23.43 0.000000000000002187 81.0
TLS3_k127_2032075_2 PFAM Flp Fap pilin component K02651 - - 0.00000000000302 68.0
TLS3_k127_2038184_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.0 1054.0
TLS3_k127_2038184_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 500.0
TLS3_k127_2038184_10 Pfam Small Multidrug Resistance protein K11741 - - 0.00000000000000000000000000000000008341 136.0
TLS3_k127_2038184_11 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000002821 134.0
TLS3_k127_2038184_12 TAP-like protein - - - 0.00000000000000000000000000004954 123.0
TLS3_k127_2038184_13 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000001339 119.0
TLS3_k127_2038184_2 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 472.0
TLS3_k127_2038184_3 of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 332.0
TLS3_k127_2038184_4 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001558 286.0
TLS3_k127_2038184_5 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005858 290.0
TLS3_k127_2038184_6 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005396 271.0
TLS3_k127_2038184_7 Haem-degrading - - - 0.00000000000000000000000000000000000000000000002397 175.0
TLS3_k127_2038184_8 Protein of unknown function (DUF423) - - - 0.000000000000000000000000000000000000000002525 161.0
TLS3_k127_2038184_9 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.000000000000000000000000000000000005028 146.0
TLS3_k127_2056541_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000002897 244.0
TLS3_k127_2071202_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009832 454.0
TLS3_k127_2071202_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 297.0
TLS3_k127_2074021_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 580.0
TLS3_k127_2074021_1 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 464.0
TLS3_k127_2074021_2 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003161 280.0
TLS3_k127_2074021_3 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000001759 179.0
TLS3_k127_2102356_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.144e-215 681.0
TLS3_k127_2102356_1 LysR substrate binding domain K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 451.0
TLS3_k127_2102356_2 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009019 247.0
TLS3_k127_2102356_3 effector of murein hydrolase - - - 0.0000000004006 61.0
TLS3_k127_2102356_5 - - - - 0.0002412 49.0
TLS3_k127_2112632_0 - - - - 0.000000000000000000000000000000000000000002947 170.0
TLS3_k127_2114529_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.022e-211 667.0
TLS3_k127_2114529_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008863 497.0
TLS3_k127_2114529_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008582 387.0
TLS3_k127_2114529_3 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 324.0
TLS3_k127_2114529_4 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000186 222.0
TLS3_k127_2114529_5 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000008002 156.0
TLS3_k127_211543_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 569.0
TLS3_k127_211543_1 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000007748 174.0
TLS3_k127_211543_2 peptidase, M13 K07386 - - 0.00002326 57.0
TLS3_k127_2136318_0 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 384.0
TLS3_k127_2136318_1 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001887 275.0
TLS3_k127_2136318_2 bacterial OsmY and nodulation domain - - - 0.000000000001703 69.0
TLS3_k127_2152113_0 Periplasmic domain of Sensor histidine kinase RisS K07638 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004546 282.0
TLS3_k127_2152113_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000001125 239.0
TLS3_k127_2152113_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000006023 55.0
TLS3_k127_2193457_0 Tripartite tricarboxylate transporter TctA family K07793 - - 2.942e-237 749.0
TLS3_k127_2193457_1 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006719 469.0
TLS3_k127_2193457_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007697 423.0
TLS3_k127_2193457_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 385.0
TLS3_k127_2193457_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 384.0
TLS3_k127_2193457_5 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000001014 189.0
TLS3_k127_2193457_6 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000000001597 174.0
TLS3_k127_2193457_7 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000008864 135.0
TLS3_k127_2193457_8 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000000173 101.0
TLS3_k127_2197730_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 564.0
TLS3_k127_2197730_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000006219 91.0
TLS3_k127_2200273_0 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 1.373e-279 873.0
TLS3_k127_2200273_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 397.0
TLS3_k127_2214700_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.664e-225 704.0
TLS3_k127_2214700_1 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 399.0
TLS3_k127_2214700_2 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 395.0
TLS3_k127_2214700_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 336.0
TLS3_k127_2214700_4 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000048 217.0
TLS3_k127_2248301_0 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 390.0
TLS3_k127_2248301_1 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 349.0
TLS3_k127_2248301_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 316.0
TLS3_k127_2248301_3 Required for insertion of 4Fe-4S clusters K15724 - - 0.00000000000000000000000000000000000000000000000000000000000197 211.0
TLS3_k127_2252969_0 transporter K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 529.0
TLS3_k127_2252969_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 426.0
TLS3_k127_2252969_2 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 334.0
TLS3_k127_2252969_3 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000001074 190.0
TLS3_k127_2252969_4 DctM subunit - - - 0.000000000000000000000000000000000001021 156.0
TLS3_k127_2252969_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000114 126.0
TLS3_k127_225755_0 - - - - 0.0000000000000000000000000000000000000000004107 168.0
TLS3_k127_225755_1 Bacterial transcriptional activator domain - - - 0.0000000000000000000000001002 118.0
TLS3_k127_2341243_0 Surface antigen K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 377.0
TLS3_k127_2341896_0 Sodium:solute symporter family K14392 - - 1.946e-196 624.0
TLS3_k127_2341896_1 Thiopurine S-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000003342 206.0
TLS3_k127_2341896_2 - - - - 0.00000000000000000000000000000000000000000000000000009263 196.0
TLS3_k127_2341896_3 - - - - 0.00000000001282 70.0
TLS3_k127_2342394_0 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 459.0
TLS3_k127_2342394_1 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000002485 184.0
TLS3_k127_2342394_2 Threonine synthase K01733 - 4.2.3.1 0.0000000000000008044 78.0
TLS3_k127_2346306_0 protein conserved in bacteria K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000394 259.0
TLS3_k127_2346306_1 surface antigen (D15) K07278 - - 0.000000000000000000000000000000000000000000000000003153 186.0
TLS3_k127_2356040_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.114e-314 975.0
TLS3_k127_2384741_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 564.0
TLS3_k127_2384741_1 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002731 256.0
TLS3_k127_2464716_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.322e-203 640.0
TLS3_k127_2464716_1 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 360.0
TLS3_k127_2464716_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000005743 144.0
TLS3_k127_2485844_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.771e-199 634.0
TLS3_k127_2485844_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 558.0
TLS3_k127_2485844_2 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 493.0
TLS3_k127_2485844_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 322.0
TLS3_k127_2485844_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000124 130.0
TLS3_k127_2500439_0 Nuclease-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 559.0
TLS3_k127_2500439_1 Fumarate hydratase (Fumerase) K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 486.0
TLS3_k127_2500439_10 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009279 282.0
TLS3_k127_2500439_11 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003149 285.0
TLS3_k127_2500439_12 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001556 264.0
TLS3_k127_2500439_13 protein-(glutamine-N5) methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000003244 227.0
TLS3_k127_2500439_14 6-pyruvoyl tetrahydropterin synthase - - - 0.0000000000000000000000000000000000000000000000000000000007034 204.0
TLS3_k127_2500439_15 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000000000004317 204.0
TLS3_k127_2500439_16 - - - - 0.00006527 54.0
TLS3_k127_2500439_2 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 462.0
TLS3_k127_2500439_3 semialdehyde reductase K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 394.0
TLS3_k127_2500439_4 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 364.0
TLS3_k127_2500439_5 Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 320.0
TLS3_k127_2500439_6 esterase K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008787 316.0
TLS3_k127_2500439_7 TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01676,K01678 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 320.0
TLS3_k127_2500439_8 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 306.0
TLS3_k127_2500439_9 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003855 289.0
TLS3_k127_2508853_0 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 430.0
TLS3_k127_2574085_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 576.0
TLS3_k127_2574085_1 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000001112 152.0
TLS3_k127_2588947_0 AMP-binding enzyme C-terminal domain K18661 - - 7.925e-215 681.0
TLS3_k127_2588947_1 ATPases associated with a variety of cellular activities K05816,K10111,K10112 - 3.6.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 496.0
TLS3_k127_2588947_10 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007604 249.0
TLS3_k127_2588947_11 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000002906 223.0
TLS3_k127_2588947_12 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000002503 194.0
TLS3_k127_2588947_13 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000001345 150.0
TLS3_k127_2588947_14 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.00000000000000000000000000002892 130.0
TLS3_k127_2588947_15 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000002177 101.0
TLS3_k127_2588947_2 Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 389.0
TLS3_k127_2588947_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 363.0
TLS3_k127_2588947_4 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009763 334.0
TLS3_k127_2588947_5 receptor K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 309.0
TLS3_k127_2588947_6 probably responsible for the translocation of the substrate across the membrane K02026,K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001386 272.0
TLS3_k127_2588947_7 Periplasmic binding protein K02016,K06858 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004291 287.0
TLS3_k127_2588947_8 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004024 273.0
TLS3_k127_2588947_9 Biopolymer transport K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006374 267.0
TLS3_k127_2603012_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 374.0
TLS3_k127_2603012_1 PFAM Glycoside hydrolase 15-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 349.0
TLS3_k127_2603012_2 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000001066 163.0
TLS3_k127_2603012_3 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000001972 131.0
TLS3_k127_2603750_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000001426 222.0
TLS3_k127_2603750_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000001844 214.0
TLS3_k127_2603750_2 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000005143 167.0
TLS3_k127_2603750_3 - - - - 0.0000000000000000000000000003063 130.0
TLS3_k127_2603750_4 BRO family, N-terminal domain - - - 0.000004496 55.0
TLS3_k127_2615703_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 8.013e-203 642.0
TLS3_k127_2615703_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 567.0
TLS3_k127_2615703_2 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007511 583.0
TLS3_k127_2615703_3 COG2148 Sugar transferases involved in lipopolysaccharide synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 358.0
TLS3_k127_2615703_4 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase - - - 0.000000000000000000000000000000000000000007752 160.0
TLS3_k127_2622872_0 Major facilitator superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 620.0
TLS3_k127_2622872_1 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004092 256.0
TLS3_k127_2622872_2 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000009102 207.0
TLS3_k127_2622872_3 Auxin-binding protein - - - 0.000000000000000000000000000000000000000000000000000000525 200.0
TLS3_k127_263009_0 Glycosyl transferases group 1 - - - 3.401e-205 644.0
TLS3_k127_263009_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 606.0
TLS3_k127_263009_2 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000008204 154.0
TLS3_k127_263009_3 Periplasmic or secreted lipoprotein K04065 - - 0.00000000000000000000000006395 119.0
TLS3_k127_2638420_0 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 428.0
TLS3_k127_2638420_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002694 275.0
TLS3_k127_2648785_0 PFAM Acyl-CoA dehydrogenase K00252 - 1.3.8.6 6.061e-201 643.0
TLS3_k127_2648785_1 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 390.0
TLS3_k127_2648785_2 lipase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009996 272.0
TLS3_k127_2648785_3 lipase activity - - - 0.00000000000000000000000000000000000003892 150.0
TLS3_k127_2654873_0 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 409.0
TLS3_k127_2654873_1 membrane K08972 - - 0.000000000000000000000000000000000001572 141.0
TLS3_k127_2654873_2 Ketopantoate reductase PanE/ApbA C terminal - - - 0.00000000000000000000000000000001333 131.0
TLS3_k127_2654873_3 Protein of unknown function (DUF2917) - - - 0.0007178 45.0
TLS3_k127_2657734_0 Extracellular solute-binding protein, family 5 middle family protein K02035 - - 3.407e-226 714.0
TLS3_k127_2657734_1 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 541.0
TLS3_k127_2657734_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 499.0
TLS3_k127_2657734_3 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 378.0
TLS3_k127_2657734_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000001221 268.0
TLS3_k127_2657734_5 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000000000000000000001468 233.0
TLS3_k127_2657734_6 COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000008209 224.0
TLS3_k127_2657734_7 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000005235 173.0
TLS3_k127_2661869_0 Peptidase family U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 490.0
TLS3_k127_2661869_1 PFAM peptidase U32 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006801 365.0
TLS3_k127_2661869_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009943 323.0
TLS3_k127_2661869_3 PFAM isocitrate isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000005607 238.0
TLS3_k127_2661869_4 cysteine dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000002627 222.0
TLS3_k127_2661869_5 Ion transport protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000001456 226.0
TLS3_k127_2661869_6 SCP-2 sterol transfer family - - - 0.00000000000000000000000000005941 132.0
TLS3_k127_2661869_7 protein conserved in bacteria - - - 0.00000000000000000000001812 102.0
TLS3_k127_2665086_0 FtsX-like permease family K02004 - - 7.741e-283 890.0
TLS3_k127_2665086_1 short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001302 312.0
TLS3_k127_2670440_0 GTP-binding protein K06207 - - 0.0 1019.0
TLS3_k127_2670440_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 324.0
TLS3_k127_2670440_2 EamA-like transporter family - - - 0.000000001757 61.0
TLS3_k127_2683948_0 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 3.512e-208 672.0
TLS3_k127_2683948_1 hemolysin iii K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000005824 220.0
TLS3_k127_2683948_2 Cyclase dehydrase - - - 0.0000000000000000000000000000000000000009976 160.0
TLS3_k127_2683948_3 Auxin Efflux Carrier K07088 - - 0.00000000000000000000000000000005312 127.0
TLS3_k127_2683948_4 glyoxalase III activity - - - 0.00000000000000000000000069 121.0
TLS3_k127_2683948_5 Protein chain release factor B K15034 - - 0.000000000000000000889 87.0
TLS3_k127_2683948_6 - - - - 0.0005921 45.0
TLS3_k127_2689257_0 Zn-ribbon protein possibly nucleic acid-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 581.0
TLS3_k127_2689257_1 ribosome binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003842 273.0
TLS3_k127_2695173_0 AcrB/AcrD/AcrF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 524.0
TLS3_k127_2695173_1 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000001006 112.0
TLS3_k127_2695187_0 AcrB/AcrD/AcrF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 518.0
TLS3_k127_2695187_1 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000000006897 113.0
TLS3_k127_2695187_2 Metal-sensitive transcriptional repressor - - - 0.000000000000000008223 86.0
TLS3_k127_2713234_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 570.0
TLS3_k127_2713234_1 COG0841 Cation multidrug efflux pump K03296,K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 471.0
TLS3_k127_2713234_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 379.0
TLS3_k127_2713234_3 Efflux transporter, outer membrane factor lipoprotein, NodT family K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 321.0
TLS3_k127_2713234_4 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000001904 223.0
TLS3_k127_2713234_5 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000003758 165.0
TLS3_k127_2713234_6 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000001638 142.0
TLS3_k127_2713234_7 Permeases of the drug metabolite transporter (DMT) superfamily K12962 - - 0.0000000001587 63.0
TLS3_k127_2714765_0 4Fe-4S dicluster domain K18930 - - 1.244e-283 889.0
TLS3_k127_2716205_0 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 600.0
TLS3_k127_2716205_1 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 309.0
TLS3_k127_2720023_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1120.0
TLS3_k127_2720023_1 acyl-CoA dehydrogenase - - - 1.279e-272 863.0
TLS3_k127_2720023_10 Limonene-1,2-epoxide hydrolase catalytic domain - - - 0.0000000000000000000000000000000001543 148.0
TLS3_k127_2720023_2 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 612.0
TLS3_k127_2720023_3 PFAM Enoyl-CoA hydratase isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 327.0
TLS3_k127_2720023_4 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 308.0
TLS3_k127_2720023_5 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 288.0
TLS3_k127_2720023_6 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000004581 231.0
TLS3_k127_2720023_7 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000005155 169.0
TLS3_k127_2720023_8 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000001282 176.0
TLS3_k127_2720023_9 PFAM DoxX family protein K15977 - - 0.00000000000000000000000000000000000008764 145.0
TLS3_k127_2723229_0 Esterase PHB depolymerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 377.0
TLS3_k127_2723229_1 copG family - - - 0.0000000000000000000000000000000000000000000000000005039 187.0
TLS3_k127_2723229_2 PFAM Peptidase M23 - - - 0.0000000000000000002645 96.0
TLS3_k127_2723229_3 Trypsin-like peptidase domain - - - 0.000000000003352 66.0
TLS3_k127_2724204_0 Phenylacetic acid degradation protein PaaY K02617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001743 262.0
TLS3_k127_2724204_1 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000007131 221.0
TLS3_k127_2724204_2 - - - - 0.000000000004334 75.0
TLS3_k127_2732293_0 Belongs to the peptidase M16 family K07263 - - 0.0 1174.0
TLS3_k127_2732293_1 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000006215 147.0
TLS3_k127_2739722_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 6.119e-259 802.0
TLS3_k127_2739722_1 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 527.0
TLS3_k127_2739722_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 486.0
TLS3_k127_2739722_3 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 397.0
TLS3_k127_2739722_4 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 362.0
TLS3_k127_2739722_5 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000001141 222.0
TLS3_k127_2739722_6 Glutamine amidotransferase class-I - - - 0.00000000000000000000000000000000000000000000000001129 185.0
TLS3_k127_2756962_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 382.0
TLS3_k127_2756962_1 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 342.0
TLS3_k127_2756962_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002265 261.0
TLS3_k127_2756962_3 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001832 256.0
TLS3_k127_2756962_4 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000001176 262.0
TLS3_k127_2756962_5 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003403 230.0
TLS3_k127_2756962_6 LysR family - - - 0.000001032 53.0
TLS3_k127_2777512_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000001073 235.0
TLS3_k127_2777512_1 Metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000002768 219.0
TLS3_k127_2777512_2 Phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000007885 124.0
TLS3_k127_2785140_0 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 409.0
TLS3_k127_2785140_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 290.0
TLS3_k127_2785140_2 PFAM AMP-dependent synthetase and ligase K01907 - 6.2.1.16 0.00000000000000000000000003852 108.0
TLS3_k127_2785140_3 - - - - 0.00000000004132 72.0
TLS3_k127_2792717_0 Histidine kinase K07649 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 536.0
TLS3_k127_2792717_1 Transcriptional regulatory protein, C terminal K02483,K07666,K07774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007535 351.0
TLS3_k127_2792717_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008783 254.0
TLS3_k127_2809211_0 Transport of potassium into the cell K03549 - - 4.423e-220 702.0
TLS3_k127_2809211_1 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 340.0
TLS3_k127_2818821_0 Peptidase family M3 K01414 - 3.4.24.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 380.0
TLS3_k127_2818821_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 303.0
TLS3_k127_2821634_0 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005942 307.0
TLS3_k127_2821634_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000003584 123.0
TLS3_k127_2825473_0 Cytoplasmic - - - 8.511e-283 874.0
TLS3_k127_2825473_1 IstB-like ATP binding protein - - - 0.000000000000000000000000000000000000000000000000000000000001481 231.0
TLS3_k127_2825473_2 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000001017 115.0
TLS3_k127_2835784_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1382.0
TLS3_k127_2835784_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009059 297.0
TLS3_k127_2835784_2 - - - - 0.0000000000000000818 81.0
TLS3_k127_2848896_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 1.908e-280 872.0
TLS3_k127_2848896_1 ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 371.0
TLS3_k127_2848896_2 TonB C terminal - - - 0.00000000000000000000000000000000000000000000000000000002176 212.0
TLS3_k127_2852660_0 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 603.0
TLS3_k127_2852660_1 DNA topoisomerase iii K03169 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 350.0
TLS3_k127_2852660_2 Nuclear protein SET K07117 - - 0.00000000000000000000000000000000000000000000000000000000001168 211.0
TLS3_k127_2852660_3 Domain of unknown function (DUF1993) K09983 - - 0.00000000000000000000000000000000003686 136.0
TLS3_k127_2852660_4 Protein of unknown function (DUF2905) - - - 0.0000000000000000000009772 97.0
TLS3_k127_2855396_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 606.0
TLS3_k127_2855396_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000001257 187.0
TLS3_k127_2878617_0 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 582.0
TLS3_k127_2878617_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 527.0
TLS3_k127_2878617_2 Na dependent nucleoside transporter K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 425.0
TLS3_k127_2878617_3 Molybdopterin biosynthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000001201 256.0
TLS3_k127_2878617_4 COG2059 Chromate transport protein ChrA K07240 - - 0.000000000000000000000000000000000000000000000005678 197.0
TLS3_k127_2878617_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000001301 169.0
TLS3_k127_2885366_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 7.13e-227 707.0
TLS3_k127_2885366_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 584.0
TLS3_k127_2885366_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 487.0
TLS3_k127_2885366_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 369.0
TLS3_k127_2885366_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 291.0
TLS3_k127_2885366_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000004547 226.0
TLS3_k127_2894922_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001125 285.0
TLS3_k127_2894922_1 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000002717 131.0
TLS3_k127_2894922_2 Putative prokaryotic signal transducing protein - - - 0.000000000000000000000000002294 121.0
TLS3_k127_2894922_3 Peptidase M48 K06013 - 3.4.24.84 0.00000000000000006736 80.0
TLS3_k127_2895866_0 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 3.504e-194 612.0
TLS3_k127_2902496_0 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 426.0
TLS3_k127_2902496_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000003574 181.0
TLS3_k127_2902496_2 cytochrome - - - 0.0000000000000000000000000000006389 128.0
TLS3_k127_2905436_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 2.318e-250 789.0
TLS3_k127_2905436_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 434.0
TLS3_k127_2905436_2 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000682 181.0
TLS3_k127_2905436_3 phosphoglycerate mutase - - - 0.00000000000000000000000000000000002912 147.0
TLS3_k127_2916607_0 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 366.0
TLS3_k127_2916607_1 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000000005665 169.0
TLS3_k127_2916607_2 dna topoisomerase III K03169 - 5.99.1.2 0.00000000000000000000000000000000000002003 144.0
TLS3_k127_2916607_3 LysM domain - - - 0.00000000000007159 74.0
TLS3_k127_2957090_0 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004348 257.0
TLS3_k127_2957090_1 - - - - 0.00000000000000000000000000000000000000000000000003362 186.0
TLS3_k127_2957090_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.0000000000000000000000000001794 115.0
TLS3_k127_2957090_3 Cupin 2, conserved barrel domain protein K21700 - - 0.0000000000000000000004437 100.0
TLS3_k127_2957090_4 Histidine kinase - - - 0.0000000003317 69.0
TLS3_k127_2978485_0 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 381.0
TLS3_k127_2978485_1 COG3245 Cytochrome c5 - - - 0.00000000000000000000000000000000000000000000000000000000000000087 235.0
TLS3_k127_2978485_2 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000000002533 186.0
TLS3_k127_2978485_3 Import inner membrane translocase, subunit - - - 0.000000000003279 70.0
TLS3_k127_2981904_0 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000269 261.0
TLS3_k127_2981904_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001646 259.0
TLS3_k127_2981904_2 Type II secretion system protein B K02451 - - 0.0000000000000000000000000000000000001356 151.0
TLS3_k127_2981904_3 Protein of unknown function (DUF2889) - - - 0.00000000000000000000000000000002879 136.0
TLS3_k127_2981904_4 SMART AAA ATPase K02450 - - 0.000000002856 58.0
TLS3_k127_2981904_5 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000001824 57.0
TLS3_k127_2991499_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 582.0
TLS3_k127_2991499_1 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003222 280.0
TLS3_k127_2991499_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000003702 93.0
TLS3_k127_3020582_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 625.0
TLS3_k127_3020582_1 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000003846 90.0
TLS3_k127_3028652_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 2.924e-236 753.0
TLS3_k127_3028652_1 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009518 288.0
TLS3_k127_3028652_2 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006104 267.0
TLS3_k127_3028652_3 Glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.0000000000000005903 78.0
TLS3_k127_3028652_4 - - - - 0.0000002371 57.0
TLS3_k127_3042889_0 Histidine kinase K14978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009429 259.0
TLS3_k127_3042889_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000999 133.0
TLS3_k127_3057974_0 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 393.0
TLS3_k127_3057974_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 322.0
TLS3_k127_3057974_2 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000001218 108.0
TLS3_k127_3057974_3 Glycine-zipper domain - - - 0.00000000000003626 76.0
TLS3_k127_3057974_4 Permeases of the major facilitator superfamily - - - 0.0006811 46.0
TLS3_k127_30669_0 argininosuccinate lyase K01755 - 4.3.2.1 1.389e-199 645.0
TLS3_k127_30669_1 LytTr DNA-binding domain K08083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003447 277.0
TLS3_k127_30669_2 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000001162 226.0
TLS3_k127_3072755_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009828 439.0
TLS3_k127_3072755_1 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 416.0
TLS3_k127_3072755_2 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000001625 266.0
TLS3_k127_3072755_3 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000002906 187.0
TLS3_k127_3072755_4 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000006171 88.0
TLS3_k127_3097713_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.845e-255 806.0
TLS3_k127_3097713_1 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004337 281.0
TLS3_k127_3097713_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000009492 196.0
TLS3_k127_3097713_3 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000001284 199.0
TLS3_k127_3097713_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000004228 156.0
TLS3_k127_311358_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 0.0 1031.0
TLS3_k127_311358_1 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 534.0
TLS3_k127_311358_10 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006808 250.0
TLS3_k127_311358_11 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000001133 219.0
TLS3_k127_311358_12 Haem-degrading K11477 - - 0.00000000000000000000000000000000000000000000000000000576 192.0
TLS3_k127_311358_13 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000000000000000000000000001303 170.0
TLS3_k127_311358_14 DUF218 domain - - - 0.000000000000000000000000000000000000006958 154.0
TLS3_k127_311358_15 NlpC/P60 family K13695,K19303 - - 0.00000000000000000000000000000000000002599 163.0
TLS3_k127_311358_16 TIGRFAM maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.00000002101 55.0
TLS3_k127_311358_2 Aminotransferase class-III K00819,K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.13,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 506.0
TLS3_k127_311358_3 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008261 455.0
TLS3_k127_311358_4 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 420.0
TLS3_k127_311358_5 histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 417.0
TLS3_k127_311358_6 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 427.0
TLS3_k127_311358_7 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 349.0
TLS3_k127_311358_8 Amidinotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001237 297.0
TLS3_k127_311358_9 lytic murein transglycosylase K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009661 274.0
TLS3_k127_3121394_0 sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009766 244.0
TLS3_k127_3121394_1 - - - - 0.000000000000000000001502 109.0
TLS3_k127_3155706_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009554 315.0
TLS3_k127_3155706_1 response regulator - - - 0.000000000000000000000000000000000000000000000003161 181.0
TLS3_k127_3155706_2 Bacterial transcriptional activator domain - - - 0.0000000001028 73.0
TLS3_k127_316300_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 397.0
TLS3_k127_316300_1 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 360.0
TLS3_k127_316300_2 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000004437 190.0
TLS3_k127_3165736_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 560.0
TLS3_k127_3165736_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 372.0
TLS3_k127_3165736_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000002034 245.0
TLS3_k127_3165736_3 Type IV pilus biogenesis K02656 - - 0.0000000000000000000000000000000000000000000000000000000002813 213.0
TLS3_k127_3165736_4 Domain of unknown function (DUF4115) K15539 - - 0.00000000000000000000000003582 121.0
TLS3_k127_3167477_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 360.0
TLS3_k127_3167477_1 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000000000000000000000273 208.0
TLS3_k127_3167477_2 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.0000000000000000006605 96.0
TLS3_k127_3167477_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000135 66.0
TLS3_k127_3193485_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 410.0
TLS3_k127_3193485_1 - - - - 0.00000000000000000000000000001376 121.0
TLS3_k127_3193485_2 - - - - 0.00000000000000000001508 93.0
TLS3_k127_3197516_0 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 5.699e-204 638.0
TLS3_k127_3197516_1 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 352.0
TLS3_k127_3197516_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000004846 131.0
TLS3_k127_3221680_0 FAD binding domain K05712 - 1.14.13.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 423.0
TLS3_k127_3221680_1 PFAM peptidase - - - 0.000000000000000000000000006754 121.0
TLS3_k127_3221680_2 Protein of unknown function (DUF2783) - - - 0.0000000000000000004065 87.0
TLS3_k127_3250891_0 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 291.0
TLS3_k127_3250891_1 Protein of unknown function (DUF418) K07148 - - 0.0000000000000000000000000000000000000000000000003592 192.0
TLS3_k127_3250891_2 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000001491 124.0
TLS3_k127_3336653_0 TRAP dicarboxylate transporter, DctM subunit K03299 - - 2.576e-247 775.0
TLS3_k127_3336653_1 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 586.0
TLS3_k127_3336653_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 557.0
TLS3_k127_3336653_3 Belongs to the UPF0307 family K09889 - - 0.0000000000000000000000000000000000000008236 154.0
TLS3_k127_335529_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 580.0
TLS3_k127_335529_1 Domain of unknown function (DUF5117) - - - 0.0000000000000000006076 93.0
TLS3_k127_340522_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 427.0
TLS3_k127_340522_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000002477 110.0
TLS3_k127_340522_2 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000001901 112.0
TLS3_k127_340522_3 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.000000000000008507 76.0
TLS3_k127_3415525_0 cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 456.0
TLS3_k127_3415525_1 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 349.0
TLS3_k127_3415525_2 Protein of unknown function (DUF1365) K09701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001085 284.0
TLS3_k127_3415525_3 Chalcone isomerase-like - - - 0.000000000000000000000000000000003965 139.0
TLS3_k127_3415525_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000001378 93.0
TLS3_k127_3434307_0 Belongs to the peptidase M24B family K01262,K01271 - 3.4.11.9,3.4.13.9 2.704e-230 729.0
TLS3_k127_3434307_1 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 345.0
TLS3_k127_3436521_0 TIGRFAM sulfate ABC transporter, permease protein CysW, sulfate ABC transporter, permease protein K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 379.0
TLS3_k127_3436521_1 transport system K02046,K15496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008677 253.0
TLS3_k127_3436521_2 histidine kinase HAMP region domain protein - - - 0.0000000001452 74.0
TLS3_k127_3449298_0 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 324.0
TLS3_k127_3449298_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000001226 239.0
TLS3_k127_3449298_2 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000006963 233.0
TLS3_k127_3449298_3 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000003656 83.0
TLS3_k127_3452147_0 Trypsin K08070 - 1.3.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 446.0
TLS3_k127_3452147_1 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 469.0
TLS3_k127_3452147_2 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005042 243.0
TLS3_k127_3452147_3 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000003916 180.0
TLS3_k127_3452147_4 Protein of unknown function (DUF3999) - - - 0.0000000000000002441 94.0
TLS3_k127_3452147_5 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000003479 76.0
TLS3_k127_3462894_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 5.683e-243 764.0
TLS3_k127_3462894_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 349.0
TLS3_k127_3464569_0 serine acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 351.0
TLS3_k127_3464569_1 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 299.0
TLS3_k127_3464569_2 SpoU rRNA Methylase family K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001044 266.0
TLS3_k127_3464569_3 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000005254 192.0
TLS3_k127_3471168_0 Protein of unknown function (DUF1538) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008296 613.0
TLS3_k127_3471168_1 COG1226 Kef-type K transport systems K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000008041 243.0
TLS3_k127_3471168_2 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000226 147.0
TLS3_k127_3471168_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000000000000000000000003 138.0
TLS3_k127_3490030_0 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005573 287.0
TLS3_k127_3490030_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000004821 198.0
TLS3_k127_3490661_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 2.552e-213 669.0
TLS3_k127_3490661_1 amino acid K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 587.0
TLS3_k127_3490661_10 phenylacetic acid degradation protein K02614 - - 0.00000000000000000000000000000000000000000000000000004615 191.0
TLS3_k127_3490661_11 Phenylacetate-CoA oxygenase subunit PaaB K02610 - - 0.0000000000000000000000000000000000000000000000000000694 190.0
TLS3_k127_3490661_2 Phenylacetate-CoA oxygenase subunit PaaA K02609 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 587.0
TLS3_k127_3490661_3 Beta-ketoacyl synthase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 581.0
TLS3_k127_3490661_4 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 546.0
TLS3_k127_3490661_5 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 K02613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 498.0
TLS3_k127_3490661_6 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 364.0
TLS3_k127_3490661_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 310.0
TLS3_k127_3490661_8 Pfam:DUF59 K02612 - - 0.000000000000000000000000000000000000000000000000000000000000000000001106 243.0
TLS3_k127_3490661_9 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000006117 220.0
TLS3_k127_3491920_0 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000228 223.0
TLS3_k127_3491920_1 chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000006514 200.0
TLS3_k127_3491920_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000001711 134.0
TLS3_k127_3491920_3 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000001173 62.0
TLS3_k127_3496757_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 389.0
TLS3_k127_3496757_1 Belongs to the UPF0337 (CsbD) family - - - 0.00000003189 60.0
TLS3_k127_3524174_0 PFAM MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000003749 152.0
TLS3_k127_3524174_1 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000000000002103 139.0
TLS3_k127_3524174_2 COG0810 Periplasmic protein TonB, links inner and outer membranes K03646 - - 0.0000000000000000000002801 107.0
TLS3_k127_3524174_3 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000007162 78.0
TLS3_k127_3526676_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 517.0
TLS3_k127_3526676_1 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009202 447.0
TLS3_k127_3526676_2 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 326.0
TLS3_k127_3526676_3 Bacterial SH3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 325.0
TLS3_k127_3526676_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004633 272.0
TLS3_k127_3526676_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001811 254.0
TLS3_k127_3526676_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001131 238.0
TLS3_k127_3526676_7 Glutathione peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000009227 227.0
TLS3_k127_3534668_0 Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 580.0
TLS3_k127_3534668_1 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 362.0
TLS3_k127_3534668_2 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000000000000000000000000001202 196.0
TLS3_k127_3534668_3 Membrane fusogenic activity K09806 - - 0.0000000000000001337 91.0
TLS3_k127_3539175_0 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006477 443.0
TLS3_k127_3539175_1 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000001448 201.0
TLS3_k127_3539175_2 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000000000000000000000000000000002478 183.0
TLS3_k127_3539705_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 4.82e-241 759.0
TLS3_k127_3539705_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 582.0
TLS3_k127_3539705_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 373.0
TLS3_k127_3539705_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 286.0
TLS3_k127_3539705_4 Preprotein translocase K03210 - - 0.0000000000000000000000000002379 131.0
TLS3_k127_354178_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1151.0
TLS3_k127_354178_1 PFAM aminotransferase, class I and II K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 511.0
TLS3_k127_354178_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000001054 267.0
TLS3_k127_354178_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000001868 218.0
TLS3_k127_354178_4 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.0003058 49.0
TLS3_k127_3546840_0 HAD-superfamily hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000007301 248.0
TLS3_k127_3546840_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000032 184.0
TLS3_k127_3546840_2 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000001257 145.0
TLS3_k127_3546840_3 Uroporphyrin-III C tetrapyrrole K07056 - 2.1.1.198 0.00000000000000001642 85.0
TLS3_k127_35469_0 Histidine kinase K02487,K06596 - - 0.0 1243.0
TLS3_k127_35469_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 9.864e-215 691.0
TLS3_k127_35469_2 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 476.0
TLS3_k127_35469_3 cheY-homologous receiver domain K02657 - - 0.00000000000000000000000000000000000000000000000000000000001033 214.0
TLS3_k127_35469_4 cheY-homologous receiver domain K02658 - - 0.00000000000000000000000000000000000000000000000000000001763 199.0
TLS3_k127_35469_5 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000000000000001736 120.0
TLS3_k127_35469_6 CheW-like domain K02659 - - 0.000000000000000000000000000002275 129.0
TLS3_k127_35469_7 KTSC domain - - - 0.000000000000009759 90.0
TLS3_k127_35469_8 PFAM Phosphomethylpyrimidine kinase type-1 K00941 - 2.7.1.49,2.7.4.7 0.00000001633 57.0
TLS3_k127_3547844_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 574.0
TLS3_k127_3547844_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006078 537.0
TLS3_k127_3547844_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 363.0
TLS3_k127_3550633_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 3.695e-213 671.0
TLS3_k127_3550633_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 551.0
TLS3_k127_3550633_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000007644 119.0
TLS3_k127_3550633_3 Actin K03569 - - 0.00000001484 57.0
TLS3_k127_3553024_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000002674 207.0
TLS3_k127_3556880_0 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 1.393e-221 691.0
TLS3_k127_3556880_1 surface antigen variable number repeat protein K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 527.0
TLS3_k127_3558087_0 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 327.0
TLS3_k127_3558087_1 TRAP transporter solute receptor TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001145 252.0
TLS3_k127_3558087_2 Acyl dehydratase - - - 0.000000000000000000000000000000000000000000003513 168.0
TLS3_k127_3558087_3 MgtC family K07507 - - 0.000000000000000000000000000000003391 134.0
TLS3_k127_3558087_4 Cysteine-rich CWC - - - 0.000001508 59.0
TLS3_k127_3560604_0 amidohydrolase K01451 - 3.5.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 425.0
TLS3_k127_3560604_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.000005017 57.0
TLS3_k127_3583224_0 ABC transporter C-terminal domain K06158 - - 5.097e-262 822.0
TLS3_k127_3583224_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 533.0
TLS3_k127_3583224_10 glyoxalase III activity - - - 0.0000000000000000000000002064 109.0
TLS3_k127_3583224_2 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 500.0
TLS3_k127_3583224_3 Type II/IV secretion system protein K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 462.0
TLS3_k127_3583224_4 C-terminal, D2-small domain, of ClpB protein K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 450.0
TLS3_k127_3583224_5 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 378.0
TLS3_k127_3583224_6 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 362.0
TLS3_k127_3583224_7 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 303.0
TLS3_k127_3583224_8 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 297.0
TLS3_k127_3583224_9 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000004765 235.0
TLS3_k127_358529_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 613.0
TLS3_k127_358529_1 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 405.0
TLS3_k127_358529_2 PFAM Cytochrome C - - - 0.0000000000000000000000000000000000003036 149.0
TLS3_k127_3586980_0 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 7.524e-272 846.0
TLS3_k127_3586980_1 short-chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 357.0
TLS3_k127_3586980_2 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000002464 222.0
TLS3_k127_3586980_3 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000008667 137.0
TLS3_k127_3586980_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000006991 115.0
TLS3_k127_3587088_0 Proton-conducting membrane transporter K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 592.0
TLS3_k127_3587088_1 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 442.0
TLS3_k127_3587088_2 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 310.0
TLS3_k127_3595706_0 Histidine kinase K07637,K07638,K07717 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009705 436.0
TLS3_k127_3595706_1 crp fnr family - - - 0.0000000000000699 71.0
TLS3_k127_3595706_2 Domain of unknown function (DUF4398) - - - 0.00000000000393 74.0
TLS3_k127_3596442_0 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 8.556e-269 843.0
TLS3_k127_3596442_1 - - - - 0.0000001453 59.0
TLS3_k127_3603055_1 Domain of unknown function (DUF4282) - - - 0.0000000000000000000001523 100.0
TLS3_k127_3603055_2 peptidyl-tyrosine sulfation - - - 0.0000000000007022 78.0
TLS3_k127_3643125_0 PFAM AFG1-family ATPase K06916 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 512.0
TLS3_k127_3643125_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 0.00000000000000000000000000000000001318 135.0
TLS3_k127_3645168_0 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 439.0
TLS3_k127_3645168_1 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001272 260.0
TLS3_k127_3645168_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000002819 105.0
TLS3_k127_3648528_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 494.0
TLS3_k127_3648528_1 2-Nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 351.0
TLS3_k127_3648528_2 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004748 293.0
TLS3_k127_3648528_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000007208 213.0
TLS3_k127_3648528_4 - - - - 0.000000000000000000000000000000000009293 141.0
TLS3_k127_3648528_5 - - - - 0.000126 52.0
TLS3_k127_3656791_0 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000763 422.0
TLS3_k127_3656791_1 TAP-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006513 271.0
TLS3_k127_3656791_2 transcriptional regulator - - - 0.000002041 51.0
TLS3_k127_3659529_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000005516 200.0
TLS3_k127_3659529_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000003271 183.0
TLS3_k127_3665201_0 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 439.0
TLS3_k127_3665201_1 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 348.0
TLS3_k127_3665201_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 349.0
TLS3_k127_3665201_3 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 327.0
TLS3_k127_3665201_4 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 333.0
TLS3_k127_3665201_5 Divalent heavy-metal cations transporter K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003018 289.0
TLS3_k127_3665201_6 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000337 252.0
TLS3_k127_3665201_7 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000004732 159.0
TLS3_k127_3665201_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000007515 91.0
TLS3_k127_3670023_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 2.446e-305 955.0
TLS3_k127_3670023_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006032 275.0
TLS3_k127_3670023_2 PFAM regulatory protein, MerR - - - 0.0000000000000000000000000000000000000000000003593 169.0
TLS3_k127_3670023_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000004871 168.0
TLS3_k127_3670023_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000004944 121.0
TLS3_k127_3670023_5 dehydrogenase - - - 0.0000002124 53.0
TLS3_k127_3686790_0 Subunit A of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K05559 - - 0.0 1032.0
TLS3_k127_3686790_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.431e-206 651.0
TLS3_k127_3686790_10 response to antibiotic - - - 0.0000000000000000000000000000006377 127.0
TLS3_k127_3686790_11 Monovalent cation proton antiporter subunit MnhG PhaG K05564 - - 0.00000000000000000000000000001166 126.0
TLS3_k127_3686790_12 PFAM multiple resistance and pH regulation protein F K05563 - - 0.00000000000000000000000004413 117.0
TLS3_k127_3686790_13 Heavy-metal-associated domain - - - 0.0000000000009194 74.0
TLS3_k127_3686790_14 signal peptide peptidase K04773 - - 0.00002798 48.0
TLS3_k127_3686790_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 477.0
TLS3_k127_3686790_3 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter MnhD subunit K00342,K05561,K05568 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 443.0
TLS3_k127_3686790_4 PFAM sodium calcium exchanger membrane region K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 430.0
TLS3_k127_3686790_5 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 301.0
TLS3_k127_3686790_6 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000001329 218.0
TLS3_k127_3686790_7 Na+/H+ ion antiporter subunit - - - 0.00000000000000000000000000000000000000002888 174.0
TLS3_k127_3686790_8 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000000000000000000003892 150.0
TLS3_k127_3686790_9 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05560 - - 0.00000000000000000000000000000003922 145.0
TLS3_k127_3688223_0 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 342.0
TLS3_k127_3688223_1 PFAM regulatory protein TetR K05501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000048 268.0
TLS3_k127_3688223_2 signal peptide peptidase K04773 - - 0.0000000000000000000000000000000000002441 146.0
TLS3_k127_3688223_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0003507 45.0
TLS3_k127_3691675_0 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 393.0
TLS3_k127_3691675_1 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006633 273.0
TLS3_k127_3691675_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000001709 277.0
TLS3_k127_3691675_3 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000001638 179.0
TLS3_k127_3691675_4 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000007745 126.0
TLS3_k127_3695708_0 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 574.0
TLS3_k127_3695708_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 359.0
TLS3_k127_3718214_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 324.0
TLS3_k127_3718214_1 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000766 254.0
TLS3_k127_3718214_2 Nudix hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003947 245.0
TLS3_k127_3718214_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000000006355 206.0
TLS3_k127_3718214_4 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000006335 134.0
TLS3_k127_3718214_5 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000001874 136.0
TLS3_k127_3718214_6 TM2 domain - - - 0.0000000000000000003724 94.0
TLS3_k127_3718214_7 Putative prokaryotic signal transducing protein - - - 0.00000000002045 64.0
TLS3_k127_3718873_0 Ferredoxin--NADP reductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000828 610.0
TLS3_k127_3718873_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 562.0
TLS3_k127_3718873_2 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009325 436.0
TLS3_k127_3718873_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 329.0
TLS3_k127_3718873_4 Ornithine cyclodeaminase/mu-crystallin family K01750,K19743 - 1.5.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 294.0
TLS3_k127_3718873_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000002964 253.0
TLS3_k127_3718873_6 Protein of unknown function (DUF2946) - - - 0.00000000000000000000000000000005967 132.0
TLS3_k127_3742278_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 7.343e-242 756.0
TLS3_k127_3742278_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 580.0
TLS3_k127_3742278_2 THUMP domain K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 424.0
TLS3_k127_3742278_3 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 346.0
TLS3_k127_3742278_4 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000143 248.0
TLS3_k127_3742278_5 2-hydroxychromene-2-carboxylate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002571 234.0
TLS3_k127_3742278_6 PFAM conserved K08973 - - 0.00000000000000000000000000000000000000000000000001238 183.0
TLS3_k127_3742278_7 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000000007789 150.0
TLS3_k127_3742278_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000001148 124.0
TLS3_k127_3745073_0 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 544.0
TLS3_k127_3745073_1 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 394.0
TLS3_k127_3745073_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 331.0
TLS3_k127_3745073_3 glyoxalase bleomycin resistance protein dioxygenase K06991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005907 239.0
TLS3_k127_3745073_4 Aldo/keto reductase family K00011 - 1.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000001983 231.0
TLS3_k127_3745073_5 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000003518 193.0
TLS3_k127_3745073_6 Auxin binding protein - - - 0.000000000000000000000000000000000000001481 151.0
TLS3_k127_3745073_7 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000001139 157.0
TLS3_k127_3745073_8 belongs to the carbohydrate kinase PfkB family K18478 - 2.7.1.184 0.00000000000000000000007784 104.0
TLS3_k127_3758763_0 Glycolate oxidase subunit GlcD K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 567.0
TLS3_k127_3758763_1 Glycolate oxidase, iron-sulfur subunit K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 571.0
TLS3_k127_3758763_2 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 437.0
TLS3_k127_3758763_3 LrgA family K06518 - - 0.000000000000000000000000000000004809 132.0
TLS3_k127_3791987_0 Belongs to the P(II) protein family - - - 0.000000000000000000000000000000000000000000000000000002162 206.0
TLS3_k127_3791987_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000007858 196.0
TLS3_k127_3791987_2 Protein of unknown function (DUF1538) - - - 0.0000000000000000000000004102 106.0
TLS3_k127_3791987_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000004464 115.0
TLS3_k127_3838283_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07812 - 1.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 537.0
TLS3_k127_3838283_1 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000119 263.0
TLS3_k127_3855411_0 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 457.0
TLS3_k127_3855411_1 Protein of unknown function, DUF599 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 315.0
TLS3_k127_3855411_2 Domain of unknown function (DUF4396) - - - 0.000000000000000000000000000001192 122.0
TLS3_k127_3867054_0 heat shock protein binding - - - 1.969e-201 640.0
TLS3_k127_3867054_1 - - - - 0.000000000000000000000000000000000000000000001237 173.0
TLS3_k127_3876882_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.117e-317 983.0
TLS3_k127_3876882_1 Nudix hydrolase K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000000002627 180.0
TLS3_k127_3876882_2 - - - - 0.000000000000000000000000000000000000000000001481 179.0
TLS3_k127_3876882_3 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000001051 147.0
TLS3_k127_3878346_0 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 297.0
TLS3_k127_3878346_1 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000008576 163.0
TLS3_k127_3883824_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1121.0
TLS3_k127_3884431_0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000001247 114.0
TLS3_k127_3884431_1 Domain of unknown function (DUF4382) - - - 0.000000000000000000001468 96.0
TLS3_k127_3884431_2 - - - - 0.00000000000000003778 91.0
TLS3_k127_389318_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 1.609e-195 624.0
TLS3_k127_389318_1 Belongs to the bacterial ribosomal protein bL33 family K02913 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000003467 107.0
TLS3_k127_3913679_0 Asparagine synthase K01953 - 6.3.5.4 1.09e-307 949.0
TLS3_k127_3913679_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 435.0
TLS3_k127_3913679_2 Protein of unknown function (DUF3485) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 391.0
TLS3_k127_3927366_0 AsmA family K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002082 292.0
TLS3_k127_3927366_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008588 273.0
TLS3_k127_3927366_2 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000000000000000000000000000003369 199.0
TLS3_k127_3927366_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000001505 120.0
TLS3_k127_3927366_4 Belongs to the UPF0337 (CsbD) family - - - 0.00000001718 57.0
TLS3_k127_3928351_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 1.885e-320 996.0
TLS3_k127_3959011_0 Uncharacterised protein family (UPF0261) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 460.0
TLS3_k127_3959011_1 Uncharacterised protein family (UPF0261) - - - 0.0000000000000000000000000000000000000000000000000000008359 196.0
TLS3_k127_3959011_2 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000009891 98.0
TLS3_k127_3962_0 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000001281 218.0
TLS3_k127_3962_1 EF-hand domain - - - 0.000000000000000000000000000000001948 138.0
TLS3_k127_3962_2 general secretion pathway protein K02457 - - 0.00000000000000000000905 99.0
TLS3_k127_3962_3 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0019835,GO:0019836,GO:0031640,GO:0035821,GO:0043436,GO:0044003,GO:0044004,GO:0044179,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046395,GO:0051213,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27 0.0000000000000004304 78.0
TLS3_k127_3962_4 Type II secretion system (T2SS), protein I K02458 - - 0.000000000000007473 80.0
TLS3_k127_3962_5 general secretion pathway protein K02452 - - 0.0000000003606 69.0
TLS3_k127_3965444_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 358.0
TLS3_k127_3965444_1 Domain of unknown function (DUF4124) - - - 0.00000000000000000002836 98.0
TLS3_k127_3965444_2 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000003431 52.0
TLS3_k127_397603_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 547.0
TLS3_k127_397603_1 Proteasome subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003823 269.0
TLS3_k127_397603_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000001471 83.0
TLS3_k127_3977833_0 PFAM ATP-binding region, ATPase domain protein K07641 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 435.0
TLS3_k127_3977833_1 Response regulator in two-component regulatory system with CreC K07663 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001013 257.0
TLS3_k127_3977833_2 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000001326 144.0
TLS3_k127_3977833_3 Domain of unknown function (DUF1840) - - - 0.0000000000000000006587 90.0
TLS3_k127_3977833_4 - - - - 0.00000000000003446 78.0
TLS3_k127_4027951_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 433.0
TLS3_k127_4027951_1 - - - - 0.0000000000341 73.0
TLS3_k127_4035615_0 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 583.0
TLS3_k127_4035615_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000857 468.0
TLS3_k127_4035615_2 Belongs to the peptidase S8 family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006636 288.0
TLS3_k127_4035615_3 lactoylglutathione lyase activity - - - 0.00000000000000000000000008702 114.0
TLS3_k127_4035615_4 proteolysis - - - 0.000000000000000004714 93.0
TLS3_k127_405266_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 499.0
TLS3_k127_405266_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 289.0
TLS3_k127_405266_2 COG1840 ABC-type Fe3 transport system, periplasmic component K02055 - - 0.00000000000004402 78.0
TLS3_k127_4086567_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 336.0
TLS3_k127_4086567_1 helix_turn_helix, Lux Regulon K13041 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 296.0
TLS3_k127_4092813_0 - - - - 0.0000000000000000000000000000000000000000000000004897 186.0
TLS3_k127_4092813_1 Cytochrome c - - - 0.00000000000000000000004562 113.0
TLS3_k127_4092813_2 HI0933-like protein K07007 - - 0.000000000000000000006351 92.0
TLS3_k127_4092813_3 Cytochrome c - - - 0.000000005649 68.0
TLS3_k127_4095082_0 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007846 521.0
TLS3_k127_4095082_1 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000000009563 104.0
TLS3_k127_410857_0 Belongs to the GcvT family K00315,K19191 - 1.5.3.19,1.5.8.4 0.0 1180.0
TLS3_k127_410857_1 Aldehyde dehydrogenase family - - - 3.919e-211 668.0
TLS3_k127_410857_2 binding-protein-dependent transport systems inner membrane component K02011 - - 2.283e-197 631.0
TLS3_k127_410857_3 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 584.0
TLS3_k127_410857_4 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 526.0
TLS3_k127_410857_5 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 410.0
TLS3_k127_410857_6 Peptidase C26 K01658,K07010 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 336.0
TLS3_k127_410857_7 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001212 260.0
TLS3_k127_410857_8 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000988 135.0
TLS3_k127_4130085_0 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 309.0
TLS3_k127_41360_0 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 329.0
TLS3_k127_41360_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 332.0
TLS3_k127_41360_2 Ferritin-like K20087 - - 0.000000000000000000000000000000000000000000000000361 178.0
TLS3_k127_41360_3 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000006293 162.0
TLS3_k127_4140685_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 392.0
TLS3_k127_4140685_1 Signal transduction histidine kinase - - - 0.0000000000000000000001054 109.0
TLS3_k127_4153202_0 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 382.0
TLS3_k127_4153202_1 membrane - - - 0.000000000000000000000000000003831 127.0
TLS3_k127_4153202_2 Belongs to the WrbA family K03809 - 1.6.5.2 0.00000000000000000000000003942 109.0
TLS3_k127_4177803_0 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 503.0
TLS3_k127_4177803_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 297.0
TLS3_k127_4177803_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000002217 173.0
TLS3_k127_4177803_3 Belongs to the UPF0434 family K09791 - - 0.0000000000000000003999 90.0
TLS3_k127_4279030_0 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 398.0
TLS3_k127_4279030_1 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 339.0
TLS3_k127_4279030_2 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00244 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000006977 265.0
TLS3_k127_4279030_3 COG2755 Lysophospholipase L1 and related esterases - - - 0.00007437 47.0
TLS3_k127_4303981_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 2.837e-290 897.0
TLS3_k127_4303981_1 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 584.0
TLS3_k127_4303981_2 Sugar (and other) transporter K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 469.0
TLS3_k127_4303981_3 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000002287 250.0
TLS3_k127_4318532_0 RNA polymerase sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 569.0
TLS3_k127_4318532_1 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002145 258.0
TLS3_k127_4318532_2 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000003776 213.0
TLS3_k127_4318532_3 Protein conserved in bacteria K04750 - - 0.0000000000000000000000000000000000000000000000004407 187.0
TLS3_k127_4318532_4 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000003016 170.0
TLS3_k127_4318532_5 Protein of unknown function (DUF1579) - - - 0.0000000000000000000000000000000000000000001375 166.0
TLS3_k127_4318772_0 ABC transporter, substrate-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 594.0
TLS3_k127_4318772_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 400.0
TLS3_k127_4318772_2 PFAM Isochorismatase - - - 0.00000000000000000000000000000000000000000000001662 178.0
TLS3_k127_4320785_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 454.0
TLS3_k127_4320785_1 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000002666 227.0
TLS3_k127_4320785_2 spore germination - - - 0.0000000000000000000000000000000000000000000000000000002071 208.0
TLS3_k127_4320785_3 OmpA-like transmembrane domain - - - 0.00000000000000000000004062 107.0
TLS3_k127_4349341_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 2.466e-204 648.0
TLS3_k127_4349341_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 481.0
TLS3_k127_4349341_2 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 458.0
TLS3_k127_4349341_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 371.0
TLS3_k127_4349341_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000003604 246.0
TLS3_k127_4349341_5 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000000000000000000003679 144.0
TLS3_k127_4349341_6 lipase activity - - - 0.000000000001005 79.0
TLS3_k127_4356112_0 E1 component K00164 - 1.2.4.2 0.0 1573.0
TLS3_k127_4356112_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K15022 - 1.17.1.10 2.346e-252 784.0
TLS3_k127_4356112_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 604.0
TLS3_k127_4356112_3 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 0.000000000000000000000000000000000000000000005177 164.0
TLS3_k127_4357762_0 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 370.0
TLS3_k127_4357762_1 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000006409 203.0
TLS3_k127_4362106_0 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000937 183.0
TLS3_k127_4362106_1 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000003416 144.0
TLS3_k127_4370478_0 PFAM Serine threonine protein kinase-related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 413.0
TLS3_k127_4370478_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004501 354.0
TLS3_k127_4370478_2 PFAM Glutaredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002924 269.0
TLS3_k127_4372868_0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 5.315e-209 659.0
TLS3_k127_4372868_1 RNA-metabolising metallo-beta-lactamase K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008135 471.0
TLS3_k127_4372868_2 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 387.0
TLS3_k127_4380180_0 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 329.0
TLS3_k127_4380180_1 Helix-hairpin-helix class 2 (Pol1 family) motifs K02335 - 2.7.7.7 0.00000000008804 64.0
TLS3_k127_4395169_0 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009005 527.0
TLS3_k127_4395169_1 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 389.0
TLS3_k127_4395169_2 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 368.0
TLS3_k127_4395169_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 289.0
TLS3_k127_4395169_4 Glutaminase - - - 0.000000009497 59.0
TLS3_k127_4402182_0 acyl-CoA dehydrogenase K00248 - 1.3.8.1 4.851e-284 883.0
TLS3_k127_4402182_1 3-hydroxyacyl-CoA dehydrogenase NAD-binding K07516 - 1.1.1.35 8.785e-266 836.0
TLS3_k127_4402182_2 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 532.0
TLS3_k127_4402182_3 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 494.0
TLS3_k127_4402182_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006457 421.0
TLS3_k127_4402182_5 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 386.0
TLS3_k127_4402182_6 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009413 336.0
TLS3_k127_4402182_7 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 335.0
TLS3_k127_4402182_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000006808 215.0
TLS3_k127_4402182_9 branched-chain amino acid K01999 - - 0.000000000000000000000000000000000000000002073 159.0
TLS3_k127_4405284_0 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 301.0
TLS3_k127_4405284_1 Protein involved in cellulose biosynthesis - - - 0.0000000000000000000000000000000002831 145.0
TLS3_k127_4405284_2 Sugar transferase, PEP-CTERM EpsH1 system associated - - - 0.0000001507 59.0
TLS3_k127_4408169_0 Subtilase family - - - 6.021e-291 914.0
TLS3_k127_4408169_1 Amidohydrolase K07045 - - 1.475e-216 681.0
TLS3_k127_4408169_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 409.0
TLS3_k127_4408169_3 CoA-transferase family III - - - 0.000000000000000000000000000000000000008629 149.0
TLS3_k127_4413505_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 377.0
TLS3_k127_4413505_1 Succinylglutamate desuccinylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004653 271.0
TLS3_k127_4413505_2 - - - - 0.0002645 47.0
TLS3_k127_4417302_0 type II secretion system protein E K02283 - - 4.553e-205 646.0
TLS3_k127_4417302_1 AAA ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 521.0
TLS3_k127_4417302_10 TadE-like protein - - - 0.00000000000000000000002596 115.0
TLS3_k127_4417302_11 - - - - 0.00000000001157 72.0
TLS3_k127_4417302_2 Pilus formation protein N terminal region K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 473.0
TLS3_k127_4417302_3 Type II secretion system (T2SS), protein F K12510 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 369.0
TLS3_k127_4417302_4 type II secretion system protein K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 351.0
TLS3_k127_4417302_5 AAA domain K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 355.0
TLS3_k127_4417302_6 Pilus assembly protein CpaB K02279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 311.0
TLS3_k127_4417302_7 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 312.0
TLS3_k127_4417302_8 LytR cell envelope-related transcriptional attenuator - - - 0.00000000000000000000000000000000000000215 161.0
TLS3_k127_4417302_9 TadE-like protein - - - 0.0000000000000000000000000003132 126.0
TLS3_k127_4421500_0 NAD-glutamate dehydrogenase K15371 - 1.4.1.2 3.337e-266 836.0
TLS3_k127_4421500_1 - - - - 0.00000000000000000000000006955 113.0
TLS3_k127_4430650_0 Belongs to the HypD family K04654 - - 5.461e-199 623.0
TLS3_k127_4430650_1 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 570.0
TLS3_k127_4430650_2 Formyl transferase, C-terminal domain K19640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 472.0
TLS3_k127_4436908_0 Circularly permuted ATP-grasp type 2 - - - 8.473e-243 764.0
TLS3_k127_4436908_1 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 457.0
TLS3_k127_4436908_2 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 349.0
TLS3_k127_4436908_3 diguanylate cyclase - - - 0.000000000000000000000000000000000000152 163.0
TLS3_k127_4449625_0 B12 binding domain K00548 - 2.1.1.13 1.745e-233 732.0
TLS3_k127_4449625_1 Belongs to the GMC oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 377.0
TLS3_k127_4453656_0 Excalibur calcium-binding domain - - - 0.000000000000000000000000000000000000000000000000000333 190.0
TLS3_k127_4453656_1 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000005078 160.0
TLS3_k127_4453656_2 DNA helicase - - - 0.000000000000000000000008633 101.0
TLS3_k127_4453656_3 MazG-like family - - - 0.00000000000000000004516 102.0
TLS3_k127_4475906_0 SpoVR like protein K06415 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 451.0
TLS3_k127_4475906_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 350.0
TLS3_k127_4481597_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 2.366e-214 678.0
TLS3_k127_4481597_1 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 461.0
TLS3_k127_4481597_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 423.0
TLS3_k127_4481597_3 nucleotidyltransferase activity - - - 0.0000000000001353 78.0
TLS3_k127_4484567_0 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 9.289e-209 662.0
TLS3_k127_4493927_0 Ferrous iron transport protein B C terminus K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 551.0
TLS3_k127_4493927_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 447.0
TLS3_k127_4493927_2 Mg2 and Co2 transporter K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 409.0
TLS3_k127_4493927_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 323.0
TLS3_k127_4493927_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000002385 64.0
TLS3_k127_4493927_5 PFAM FeoA family protein K04758 - - 0.000000001674 62.0
TLS3_k127_4495789_0 protein involved in propionate catabolism - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 557.0
TLS3_k127_4495789_1 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 310.0
TLS3_k127_4495789_2 LysR substrate binding domain - - - 0.0000000000000000001538 89.0
TLS3_k127_4503218_0 Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 561.0
TLS3_k127_4503218_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 401.0
TLS3_k127_4503218_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate - - - 0.000000000000000000000000000000000000000000000000000000000000000001608 248.0
TLS3_k127_4503218_3 Belongs to the CarB family K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000004888 203.0
TLS3_k127_4520341_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 550.0
TLS3_k127_4520341_1 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 469.0
TLS3_k127_4520341_2 Protein of unknown function (DUF3641) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 453.0
TLS3_k127_4520341_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000003283 264.0
TLS3_k127_4520341_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000009707 226.0
TLS3_k127_4520341_5 Transmembrane anti-sigma factor - - - 0.000001893 53.0
TLS3_k127_4601023_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 524.0
TLS3_k127_4601023_1 dihydroorotase multifunctional complex type K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004501 508.0
TLS3_k127_4601023_2 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 396.0
TLS3_k127_4601023_3 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 347.0
TLS3_k127_4601023_4 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004582 262.0
TLS3_k127_4601023_5 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000008055 206.0
TLS3_k127_4601023_6 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000001677 190.0
TLS3_k127_4601023_7 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000248 194.0
TLS3_k127_4601023_8 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000001273 141.0
TLS3_k127_4606593_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008561 607.0
TLS3_k127_4606593_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 522.0
TLS3_k127_4606593_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 323.0
TLS3_k127_4606593_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000482 219.0
TLS3_k127_4613045_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 526.0
TLS3_k127_4613045_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009608 357.0
TLS3_k127_4613045_2 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 330.0
TLS3_k127_4613045_3 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000000000000000000000000005557 229.0
TLS3_k127_4613045_4 cobalamin synthesis CobW domain protein - - - 0.000000002665 61.0
TLS3_k127_462160_0 Alpha beta hydrolase K03821 - - 1.391e-207 664.0
TLS3_k127_462160_1 PFAM Peptidoglycan-binding domain 1 protein K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 578.0
TLS3_k127_462160_2 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 547.0
TLS3_k127_462160_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001015 266.0
TLS3_k127_462160_4 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000000000000000000001375 222.0
TLS3_k127_462160_5 - - - - 0.000004945 53.0
TLS3_k127_462160_6 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00005684 46.0
TLS3_k127_4641282_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 586.0
TLS3_k127_4641282_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 534.0
TLS3_k127_4641282_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004596 280.0
TLS3_k127_4641282_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000002421 125.0
TLS3_k127_4652425_0 VWA domain containing CoxE-like protein K09989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007603 525.0
TLS3_k127_4652425_1 ATPase (AAA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 488.0
TLS3_k127_4652425_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 328.0
TLS3_k127_4652425_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001745 275.0
TLS3_k127_4652425_4 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004216 250.0
TLS3_k127_4652425_5 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000004348 238.0
TLS3_k127_4652425_6 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000000000000002156 196.0
TLS3_k127_4652425_7 cytochrome - - - 0.000000000000000000000001751 114.0
TLS3_k127_4652425_8 PFAM Cytochrome c, class I - - - 0.000000000000000000000001938 118.0
TLS3_k127_4673131_0 Polysaccharide chain length determinant protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 495.0
TLS3_k127_4673131_1 COG2148 Sugar transferases involved in lipopolysaccharide synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 334.0
TLS3_k127_4673131_2 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000105 280.0
TLS3_k127_4673131_3 AAA domain K08252,K16692 - 2.7.10.1 0.0000000000000008523 82.0
TLS3_k127_4680394_0 Secretin and TonB N terminus short domain K02666 - - 1.171e-234 751.0
TLS3_k127_4680394_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000006093 204.0
TLS3_k127_4680394_2 Pilus assembly protein, PilP K02665 - - 0.000000000000000000000000000000000001148 141.0
TLS3_k127_4732707_0 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 317.0
TLS3_k127_4732707_1 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000003299 214.0
TLS3_k127_4732707_2 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000001559 175.0
TLS3_k127_4732707_3 Protein of unknown function (DUF2459) - - - 0.000000000000000000000000000000000000000002444 168.0
TLS3_k127_4734441_0 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000628 340.0
TLS3_k127_4734441_1 Sigma-70, region 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 286.0
TLS3_k127_4734441_2 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002073 247.0
TLS3_k127_4734441_3 epimerase - - - 0.000000000000007538 76.0
TLS3_k127_4743475_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 354.0
TLS3_k127_4743475_1 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 348.0
TLS3_k127_4743475_10 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 - 3.1.3.77 0.0000000000000000000000000000000000000000000000000000000000003272 226.0
TLS3_k127_4743475_11 PilZ domain K02676 - - 0.000000000000000000000000000000000000000000001672 168.0
TLS3_k127_4743475_12 Domain of unknown function (DUF4936) - - - 0.000002003 55.0
TLS3_k127_4743475_2 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 352.0
TLS3_k127_4743475_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 352.0
TLS3_k127_4743475_4 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 GO:0000096,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0010309,GO:0016491,GO:0016701,GO:0016702,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0051213,GO:0055114,GO:0071704,GO:1901564,GO:1901605 1.13.11.53,1.13.11.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001559 271.0
TLS3_k127_4743475_5 DNA polymerase III, delta' K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000001453 270.0
TLS3_k127_4743475_6 Aminomethyltransferase folate-binding domain K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002963 258.0
TLS3_k127_4743475_7 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.00000000000000000000000000000000000000000000000000000000000000000297 247.0
TLS3_k127_4743475_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000001649 241.0
TLS3_k127_4743475_9 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000006154 230.0
TLS3_k127_4773588_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1439.0
TLS3_k127_4773588_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 531.0
TLS3_k127_4773588_2 TIGRFAM chorismate mutase domain of proteobacterial P-protein, clade 2 K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 495.0
TLS3_k127_4773588_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 499.0
TLS3_k127_4773588_4 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 482.0
TLS3_k127_4773588_5 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000002713 256.0
TLS3_k127_4773588_6 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000001487 221.0
TLS3_k127_4773588_7 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000003111 127.0
TLS3_k127_4800721_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.185e-248 779.0
TLS3_k127_4800721_1 Transcriptional regulator K13634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000656 381.0
TLS3_k127_4814013_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 421.0
TLS3_k127_4814013_1 Catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5- (5- phosphoribosylamino)methylideneamino imidazole-4-carboxamide K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 399.0
TLS3_k127_4814013_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 289.0
TLS3_k127_4814013_3 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000006921 206.0
TLS3_k127_4814013_4 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000001901 194.0
TLS3_k127_4814013_5 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000000000000000009412 184.0
TLS3_k127_4814013_6 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000000000000000000000000000002136 157.0
TLS3_k127_4814013_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000000000005258 132.0
TLS3_k127_4814013_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000001458 104.0
TLS3_k127_4831591_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1287.0
TLS3_k127_4831591_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 556.0
TLS3_k127_4831591_2 ATPase (AAA superfamily) K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 369.0
TLS3_k127_4831591_3 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 322.0
TLS3_k127_4831591_4 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002907 295.0
TLS3_k127_4831591_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000002944 133.0
TLS3_k127_4831591_6 peptidase K08259 - 3.4.24.75 0.00000000000000000002585 92.0
TLS3_k127_4831591_7 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000002563 89.0
TLS3_k127_4882461_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 300.0
TLS3_k127_4882461_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000009918 146.0
TLS3_k127_4882715_0 Alpha-amylase domain K01187 - 3.2.1.20 2.498e-234 743.0
TLS3_k127_4882715_1 PFAM Conserved TM helix repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000003985 241.0
TLS3_k127_4882715_2 PFAM glycoside hydrolase, family 13 domain protein K01214,K02438 - 3.2.1.196,3.2.1.68 0.00000000000000000000000000000000000000000000000001295 183.0
TLS3_k127_4935305_0 Dynamin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 477.0
TLS3_k127_4935305_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 383.0
TLS3_k127_4935305_2 a g-specific adenine glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 382.0
TLS3_k127_4935305_3 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 344.0
TLS3_k127_4935305_4 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000000006544 213.0
TLS3_k127_4935305_5 PFAM peptidase S16 lon domain protein K07157 - - 0.000000000000000000000000000000000000000000000000000000388 199.0
TLS3_k127_4935305_6 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000002707 133.0
TLS3_k127_4935305_7 Phosphate starvation-inducible protein, PSIF - - - 0.0000000000000000001269 94.0
TLS3_k127_5024282_0 COG1538 Outer membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000003163 220.0
TLS3_k127_5024282_1 Copper binding periplasmic protein CusF K07810 - - 0.00004156 46.0
TLS3_k127_5032_0 Dehydrogenase K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 480.0
TLS3_k127_5032_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009143 379.0
TLS3_k127_5032_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 359.0
TLS3_k127_5032_3 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.000000000000000000000001087 104.0
TLS3_k127_5032346_0 Soluble lytic murein K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 571.0
TLS3_k127_5032346_1 NAD dependent epimerase dehydratase family protein K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 362.0
TLS3_k127_5032346_2 glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000003177 250.0
TLS3_k127_5032346_3 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000002853 236.0
TLS3_k127_5032346_4 Transcriptional regulator K03566 - - 0.0000000000000000000000000000000000000000000000000000000000002036 221.0
TLS3_k127_5032346_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000006705 167.0
TLS3_k127_5032346_6 Protein of unknown function (DUF3144) - - - 0.000000002033 62.0
TLS3_k127_5069829_0 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000002591 217.0
TLS3_k127_5069829_1 Protein of unknown function (DUF4236) - - - 0.000000000000000000002964 110.0
TLS3_k127_5086694_0 General secretion pathway protein I K02458 - - 0.0000000000000000000004427 103.0
TLS3_k127_5086694_1 general secretion pathway protein K02459 - - 0.00000000000000004711 92.0
TLS3_k127_5086694_2 general secretion pathway protein K K02460 - - 0.0000000002324 71.0
TLS3_k127_5170217_0 helicase K03722 - 3.6.4.12 5.405e-202 649.0
TLS3_k127_5170217_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 340.0
TLS3_k127_5170217_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009909 288.0
TLS3_k127_5170217_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000001686 248.0
TLS3_k127_5170217_4 phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000001025 228.0
TLS3_k127_5170217_5 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000001861 169.0
TLS3_k127_5170217_6 Protein of unknown function (DUF465) - - - 0.000000000000002707 79.0
TLS3_k127_5170217_7 - - - - 0.00002982 53.0
TLS3_k127_5177417_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 341.0
TLS3_k127_5177417_1 Glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 0.000000000000000000000000000000000000000000000000000000004094 202.0
TLS3_k127_5177417_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000001869 151.0
TLS3_k127_5178318_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 335.0
TLS3_k127_5178318_1 Cation transport regulator - - - 0.0000000000000000000000000000000000000336 158.0
TLS3_k127_5178318_2 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.0000000000000000008187 99.0
TLS3_k127_5189988_0 Peptidase family M3 K01392 - 3.4.24.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 320.0
TLS3_k127_5189988_1 Universal stress protein family - - - 0.000000000000000000000000000001021 130.0
TLS3_k127_5196361_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 1.343e-214 681.0
TLS3_k127_5196361_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 417.0
TLS3_k127_5196361_2 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001168 269.0
TLS3_k127_5196361_3 Proton-conducting membrane transporter K12141 - - 0.0000000000000000000000000000000000006995 139.0
TLS3_k127_5196361_4 (Lipo)protein - - - 0.0000000000000000000000001595 112.0
TLS3_k127_5196361_5 Protein of unknown function (DUF4019) - - - 0.000000000000000000007435 100.0
TLS3_k127_5196361_6 Sulfite exporter TauE/SafE K07090 - - 0.000000000000009866 75.0
TLS3_k127_5202529_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 330.0
TLS3_k127_5202529_1 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001163 268.0
TLS3_k127_5202529_2 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000004907 180.0
TLS3_k127_5207219_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 516.0
TLS3_k127_5207219_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 445.0
TLS3_k127_5207219_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 347.0
TLS3_k127_5207219_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 324.0
TLS3_k127_5207219_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000005988 125.0
TLS3_k127_5207219_5 Deoxynucleoside kinase - - - 0.00000000001198 64.0
TLS3_k127_5209024_0 o-acetylhomoserine K01740 - 2.5.1.49 1.867e-223 699.0
TLS3_k127_5209024_1 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 436.0
TLS3_k127_5209024_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004685 284.0
TLS3_k127_5209024_3 Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000000000000000000000000000000000007848 209.0
TLS3_k127_5209024_4 UPF0761 membrane protein K07058 - - 0.0000000000000000000000000000000002386 139.0
TLS3_k127_5209024_5 Protein of unknown function (DUF3079) - - - 0.0000000000000000000000002457 106.0
TLS3_k127_5209024_6 cyclic nucleotide binding K10914 - - 0.000000000000000000004512 99.0
TLS3_k127_5209024_7 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.0000000000007779 78.0
TLS3_k127_5209888_0 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 523.0
TLS3_k127_5209888_1 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 415.0
TLS3_k127_5209888_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000007721 219.0
TLS3_k127_5209888_3 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000001062 191.0
TLS3_k127_5209972_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 313.0
TLS3_k127_5209972_1 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000000006022 247.0
TLS3_k127_5209972_2 Bacterial protein of unknown function (DUF924) - - - 0.00000000000000000000000000000000000000000000000000000000000002316 220.0
TLS3_k127_5218095_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 1.422e-284 880.0
TLS3_k127_5218095_1 Protein of unknown function (DUF1847) - - - 0.0000000000000001301 80.0
TLS3_k127_5218798_0 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006554 255.0
TLS3_k127_5218798_1 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.000000000000002389 79.0
TLS3_k127_5221341_0 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 394.0
TLS3_k127_5221341_1 Threonyl alanyl tRNA synthetase K07050 - - 0.00000000000000000000000006619 112.0
TLS3_k127_5241635_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000706 445.0
TLS3_k127_5241635_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 385.0
TLS3_k127_5241635_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 310.0
TLS3_k127_5241635_3 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000000000000000008229 181.0
TLS3_k127_5241635_4 Protein of unknown function (DUF454) K09790 - - 0.00000000000000000000000000005002 122.0
TLS3_k127_5241635_5 Protein of unknown function (DUF2905) - - - 0.0000000000000001426 81.0
TLS3_k127_5242188_0 Putative diguanylate phosphodiesterase - - - 0.000000000000000000003466 96.0
TLS3_k127_5261188_0 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 323.0
TLS3_k127_5261188_1 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.00000000000000000000000004421 108.0
TLS3_k127_5261188_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000002015 116.0
TLS3_k127_5277942_0 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 446.0
TLS3_k127_5277942_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 428.0
TLS3_k127_5277942_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 423.0
TLS3_k127_5277942_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 387.0
TLS3_k127_5277942_4 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 309.0
TLS3_k127_5284090_0 CoA-transferase family III K07749 - 2.8.3.16 2.913e-196 620.0
TLS3_k127_5284090_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008952 302.0
TLS3_k127_5284090_2 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 287.0
TLS3_k127_5284090_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001644 276.0
TLS3_k127_5284090_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000000000001268 173.0
TLS3_k127_5284090_5 MAPEG family - - - 0.000000000000000000000000000000000000414 144.0
TLS3_k127_5301100_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781,K20023 - 4.2.1.156,4.2.1.42,5.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 493.0
TLS3_k127_5301100_1 Putative 2OG-Fe(II) oxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000224 266.0
TLS3_k127_5305471_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 520.0
TLS3_k127_5305471_1 Smr protein MutS2 - - - 0.000000000000000000000000000000000000000000000000000000000000000002696 232.0
TLS3_k127_5305471_2 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000004873 222.0
TLS3_k127_5305471_3 Histidine kinase - - - 0.000000000000000000000002404 115.0
TLS3_k127_5305471_4 UPF0126 domain - - - 0.000000000000000000001032 96.0
TLS3_k127_5305471_5 LytTr DNA-binding domain - - - 0.0000000001244 62.0
TLS3_k127_5305857_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 601.0
TLS3_k127_5305857_1 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 345.0
TLS3_k127_5305857_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 311.0
TLS3_k127_5305857_3 Belongs to the ComB family K05979 - 3.1.3.71 0.00000000000000000000000000000000000000000000000000000000000004812 221.0
TLS3_k127_5305857_4 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000003021 208.0
TLS3_k127_5332653_0 Molecular chaperone. Has ATPase activity K04079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 549.0
TLS3_k127_5332653_1 TIGRFAM phenazine biosynthesis protein PhzF family K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000005016 261.0
TLS3_k127_5332653_2 Copper resistance protein D - - - 0.000000000000000000000000271 108.0
TLS3_k127_5386979_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 2.118e-314 985.0
TLS3_k127_5386979_1 Metallopeptidase family M24 K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 462.0
TLS3_k127_5386979_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009813 437.0
TLS3_k127_5386979_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 387.0
TLS3_k127_5386979_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000006607 188.0
TLS3_k127_5390709_0 Domain of unknown function (DUF4153) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 575.0
TLS3_k127_5390709_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000001015 173.0
TLS3_k127_5390709_2 formate dehydrogenase K00127,K08350 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:1902494 - 0.00000000000000000000000000000003872 128.0
TLS3_k127_5390709_3 ROK family K00845,K00847,K00884 - 2.7.1.2,2.7.1.4,2.7.1.59 0.0000000000000006346 79.0
TLS3_k127_5400783_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 5e-323 1005.0
TLS3_k127_5400783_1 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000001295 123.0
TLS3_k127_5400783_2 Copper resistance protein D - - - 0.00000000001267 77.0
TLS3_k127_5422328_0 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 333.0
TLS3_k127_5422328_1 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 334.0
TLS3_k127_5422328_2 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000294 285.0
TLS3_k127_5422328_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000001303 249.0
TLS3_k127_5422328_4 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000285 207.0
TLS3_k127_5422328_5 Redoxin - - - 0.00000000000000000000000000000000000000000000000000005117 192.0
TLS3_k127_5422328_6 TPM domain - - - 0.0000000000000000000000000000000000000000000000000000602 191.0
TLS3_k127_5422328_7 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000009122 158.0
TLS3_k127_5422328_8 Flavin reductase like domain - - - 0.000000000000000000000000000002059 123.0
TLS3_k127_5422328_9 Domain of unknown function (DUF4266) - - - 0.000000000000000003392 94.0
TLS3_k127_5481858_0 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 406.0
TLS3_k127_5481858_1 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000000000000000000000000000436 162.0
TLS3_k127_5481858_2 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000000000000008553 140.0
TLS3_k127_5481858_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000006768 112.0
TLS3_k127_5486478_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 5.264e-196 621.0
TLS3_k127_5486478_1 COG1840 ABC-type Fe3 transport system, periplasmic component K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 486.0
TLS3_k127_5486478_2 Belongs to the ABC transporter superfamily K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 421.0
TLS3_k127_5486478_3 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 375.0
TLS3_k127_5486478_4 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 376.0
TLS3_k127_5486478_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 367.0
TLS3_k127_5486478_6 Binding-protein-dependent transport system inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 368.0
TLS3_k127_5495944_0 permease K07086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 361.0
TLS3_k127_5495944_1 NUDIX domain - - - 0.0000000000000000000000000000000001001 139.0
TLS3_k127_5495944_2 nitrogen regulatory protein P-II - - - 0.0000000000000000000000000000001644 126.0
TLS3_k127_5537915_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.407e-246 769.0
TLS3_k127_5537915_1 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007459 299.0
TLS3_k127_5537915_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.000008071 55.0
TLS3_k127_5541699_0 Spermidine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006778 274.0
TLS3_k127_5541699_1 Protein of unknown function (DUF1631) - - - 0.000000000000000000000000000000000000000000000000000000000006675 234.0
TLS3_k127_5541699_2 Protein of unknown function (DUF1631) - - - 0.00000000000000000000000000000000000000000000005942 191.0
TLS3_k127_5599172_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 597.0
TLS3_k127_5599172_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006692 316.0
TLS3_k127_5645207_0 Atp-dependent helicase K03578 - 3.6.4.13 7.922e-303 936.0
TLS3_k127_5645207_1 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 587.0
TLS3_k127_5645207_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00016,K00024 - 1.1.1.27,1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 381.0
TLS3_k127_5645207_3 Ferredoxin - - - 0.00000000000000000000000000000000000000000000001469 174.0
TLS3_k127_5645207_4 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000000001231 173.0
TLS3_k127_5645207_5 Prolyl oligopeptidase family - - - 0.00000001887 58.0
TLS3_k127_5652316_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 7.489e-213 678.0
TLS3_k127_5652316_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 607.0
TLS3_k127_5675179_0 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000005542 201.0
TLS3_k127_5675179_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0007154,GO:0007165,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0015688,GO:0015833,GO:0015889,GO:0015891,GO:0015893,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019062,GO:0019904,GO:0022610,GO:0023052,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0031992,GO:0032991,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0042914,GO:0043213,GO:0044403,GO:0044406,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0044650,GO:0046813,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0051704,GO:0051716,GO:0060089,GO:0065007,GO:0071575,GO:0071702,GO:0071705,GO:0071944,GO:0098002,GO:0098552,GO:0098670,GO:0098796,GO:0098797,GO:1901678 - 0.00002046 53.0
TLS3_k127_5692742_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 1.914e-212 664.0
TLS3_k127_5692742_1 Aldolase K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 409.0
TLS3_k127_5692742_2 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 398.0
TLS3_k127_5692742_3 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 290.0
TLS3_k127_5722574_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 479.0
TLS3_k127_5722574_1 PEP-CTERM exosortase 1-associated glycosyltransferase, Daro_2409 family protein - - - 0.000000000000001599 77.0
TLS3_k127_5743902_0 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 347.0
TLS3_k127_5743902_1 Domain of unknown function (DUF4398) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000226 263.0
TLS3_k127_5749288_0 Peptidase M61 - - - 7.816e-220 700.0
TLS3_k127_5749288_1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005259 281.0
TLS3_k127_5749288_2 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000009259 258.0
TLS3_k127_5749288_3 Domain of unknown function (DUF4396) - - - 0.00000000000000000000000000000000000003079 147.0
TLS3_k127_5771370_0 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 466.0
TLS3_k127_5771370_1 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 420.0
TLS3_k127_5771370_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 388.0
TLS3_k127_5771370_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 338.0
TLS3_k127_5771370_4 signal peptide protein - - - 0.000000000000000000000000000000000000000000000004692 182.0
TLS3_k127_5779004_0 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.0 1401.0
TLS3_k127_5779004_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000002036 262.0
TLS3_k127_5807290_0 COG3267 Type II secretory pathway, component ExeA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 350.0
TLS3_k127_5807290_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000002821 113.0
TLS3_k127_5807290_2 TIGRFAM PEP-CTERM system associated protein - - - 0.000004204 52.0
TLS3_k127_5822133_0 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000001059 143.0
TLS3_k127_5857578_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1280.0
TLS3_k127_5857578_1 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 583.0
TLS3_k127_5857578_2 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 524.0
TLS3_k127_5857578_3 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000762 496.0
TLS3_k127_5857578_4 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 419.0
TLS3_k127_5857578_5 - - - - 0.0000000000000000000000000000000000000000000000000000000003099 209.0
TLS3_k127_5909099_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 1.707e-195 617.0
TLS3_k127_5909099_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006422 385.0
TLS3_k127_5909099_2 Belongs to the malate synthase family K01638 - 2.3.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 327.0
TLS3_k127_5909099_3 Haloacid dehalogenase, type II K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000008214 250.0
TLS3_k127_5909099_4 ATPase MipZ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000006905 236.0
TLS3_k127_5928911_0 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002303 269.0
TLS3_k127_5928911_1 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.0000000000000000000000000000000000000000000000000000000000000001644 224.0
TLS3_k127_6030809_0 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003751 243.0
TLS3_k127_6030809_1 Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000000002929 227.0
TLS3_k127_6030809_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000003158 154.0
TLS3_k127_6030809_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000008161 120.0
TLS3_k127_6030809_4 Transglycosylase associated protein - - - 0.00003292 49.0
TLS3_k127_6042717_0 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 0.0 1050.0
TLS3_k127_6042717_1 Protein of unknown function (DUF2848) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005853 284.0
TLS3_k127_6042717_2 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000003502 218.0
TLS3_k127_6051052_0 Belongs to the GARS family K01945 - 6.3.4.13 8.14e-207 653.0
TLS3_k127_6051052_1 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 437.0
TLS3_k127_6051052_2 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 435.0
TLS3_k127_6051052_3 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007713 263.0
TLS3_k127_6051052_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000000006072 192.0
TLS3_k127_6051052_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000001343 134.0
TLS3_k127_6051052_6 Domain of unknown function (DUF2383) - - - 0.00000000000000000000000007154 113.0
TLS3_k127_6051907_0 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 3.097e-239 747.0
TLS3_k127_6051907_1 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 615.0
TLS3_k127_6051907_2 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006512 478.0
TLS3_k127_6051907_3 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 428.0
TLS3_k127_6051907_4 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 388.0
TLS3_k127_6051907_5 HemY protein N-terminus K02498 - - 0.00000000000000000000000000000000000000000000000000000000001382 219.0
TLS3_k127_6051907_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000005356 189.0
TLS3_k127_6051907_7 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0005003 45.0
TLS3_k127_6057049_0 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.0 1047.0
TLS3_k127_6057049_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 1.987e-301 936.0
TLS3_k127_6057049_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.497e-246 764.0
TLS3_k127_6057049_3 Catalyzes the transfer of electrons from NADH to quinone K00342 - 1.6.5.3 1.163e-224 706.0
TLS3_k127_6057049_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972 530.0
TLS3_k127_6057049_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 304.0
TLS3_k127_6057049_6 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000003282 211.0
TLS3_k127_6057049_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000006266 156.0
TLS3_k127_6059639_0 alpha amylase catalytic K05343 - 3.2.1.1,5.4.99.16 1.243e-252 787.0
TLS3_k127_6059639_1 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.00000000000000002986 82.0
TLS3_k127_6064990_0 Membrane-bound lytic murein transglycosylase K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 394.0
TLS3_k127_6064990_1 PFAM ApaG domain protein K06195 - - 0.0000000000000000000000000000000000000000000000000000001744 196.0
TLS3_k127_6064990_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000302 177.0
TLS3_k127_6065511_0 PFAM glycosyl transferase family 51 - - - 0.000000000000000000000000000000000000000000000000000000000000000009974 251.0
TLS3_k127_6065511_1 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000000000003217 195.0
TLS3_k127_6065511_2 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000005613 178.0
TLS3_k127_6065511_3 - - - - 0.00000000000000000000000000000000002302 151.0
TLS3_k127_6065511_4 - - - - 0.00000000000000001043 89.0
TLS3_k127_6065511_5 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0000000003577 60.0
TLS3_k127_6076237_0 Glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 2.448e-213 676.0
TLS3_k127_6076237_1 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001053 272.0
TLS3_k127_6076237_2 CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000006033 224.0
TLS3_k127_6076237_3 Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers K06955 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050664,GO:0051287,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000009394 225.0
TLS3_k127_6079518_0 GMC oxidoreductase K03333 - 1.1.3.6 2.718e-208 665.0
TLS3_k127_6079518_1 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002074 277.0
TLS3_k127_6079518_2 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000008779 209.0
TLS3_k127_6079518_3 PFAM Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000001471 208.0
TLS3_k127_6079518_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000001923 175.0
TLS3_k127_6079518_5 Regulatory protein ArsR K03892 - - 0.000000000000000000000000000000002584 132.0
TLS3_k127_6081217_0 type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 587.0
TLS3_k127_6081217_1 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 583.0
TLS3_k127_6081217_10 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000002032 242.0
TLS3_k127_6081217_11 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000006692 209.0
TLS3_k127_6081217_12 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000003287 166.0
TLS3_k127_6081217_13 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000001545 168.0
TLS3_k127_6081217_14 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000002672 143.0
TLS3_k127_6081217_15 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000006755 153.0
TLS3_k127_6081217_16 Type II secretory pathway, pseudopilin - - - 0.0000000000000000000000000000001353 134.0
TLS3_k127_6081217_17 SCO1/SenC K07152 - - 0.0000000000000000000000000000005228 133.0
TLS3_k127_6081217_18 - - - - 0.000000000000000001177 99.0
TLS3_k127_6081217_19 Serine aminopeptidase, S33 - - - 0.00000000000000007926 82.0
TLS3_k127_6081217_2 type II secretion system protein E K02454,K02652,K12276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 582.0
TLS3_k127_6081217_20 - - - - 0.000000000000006908 85.0
TLS3_k127_6081217_21 PFAM SMP-30 Gluconolaconase - - - 0.0000000000002029 85.0
TLS3_k127_6081217_22 carbon utilization - - - 0.00000000003701 76.0
TLS3_k127_6081217_23 - - - - 0.0000004372 59.0
TLS3_k127_6081217_24 - - - - 0.000007485 59.0
TLS3_k127_6081217_3 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 378.0
TLS3_k127_6081217_4 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 369.0
TLS3_k127_6081217_5 Type II secretion system (T2SS), protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001026 289.0
TLS3_k127_6081217_6 helix_turn_helix, Lux Regulon K14979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003553 269.0
TLS3_k127_6081217_7 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000001372 241.0
TLS3_k127_6081217_8 His Kinase A (phospho-acceptor) domain K02484,K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000006308 249.0
TLS3_k127_6081217_9 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000002538 247.0
TLS3_k127_6081322_0 ATPase involved in DNA repair - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 608.0
TLS3_k127_6081322_1 ribosome binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 406.0
TLS3_k127_6082698_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1289.0
TLS3_k127_6082698_1 PFAM NUDIX hydrolase K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000005673 210.0
TLS3_k127_6082698_2 pathogenesis - - - 0.000000000000000000000000000000000000000000000000000007808 200.0
TLS3_k127_6082698_3 peptidase M48, Ste24p - - - 0.00000000000000000000000000000000000000000004335 174.0
TLS3_k127_6082698_4 - - - - 0.000000000000000000000000000000000000000002172 165.0
TLS3_k127_6082698_5 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000006111 155.0
TLS3_k127_6082698_6 PFAM GCN5-related N-acetyltransferase K03825 - - 0.0000000000000000000000000000000000005571 162.0
TLS3_k127_6082698_7 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000486 124.0
TLS3_k127_6082698_8 Belongs to the UPF0145 family - - - 0.000000000000000000000000000001149 134.0
TLS3_k127_6082698_9 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000001551 121.0
TLS3_k127_6088766_0 Nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 602.0
TLS3_k127_6088766_1 Reversible hydration of carbon dioxide K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002091 280.0
TLS3_k127_6088766_2 Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001217 272.0
TLS3_k127_6088766_3 NnrS protein K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000331 269.0
TLS3_k127_6088766_4 TIGRFAM nitrate reductase molybdenum cofactor assembly chaperone K00373 - - 0.000000000000000000000000000000000000002906 166.0
TLS3_k127_6088766_5 Hemerythrin HHE cation binding domain protein - - - 0.0000000000000000000000000000002676 131.0
TLS3_k127_6088766_6 Invasion gene expression up-regulator, SirB - - - 0.00000000000000000000000001539 113.0
TLS3_k127_6107622_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 583.0
TLS3_k127_6141463_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 467.0
TLS3_k127_6141463_1 Sugar transferase, PEP-CTERM EpsH1 system associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 436.0
TLS3_k127_6141463_2 Protein of unknown function (DUF3485) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 409.0
TLS3_k127_6141463_3 polysaccharide deactylase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 393.0
TLS3_k127_6141463_4 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000004506 189.0
TLS3_k127_6149866_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 1.551e-221 707.0
TLS3_k127_6154771_0 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 297.0
TLS3_k127_6154771_1 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003553 281.0
TLS3_k127_6154771_2 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000001848 183.0
TLS3_k127_6154771_3 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000002078 164.0
TLS3_k127_6154771_4 LemA family K03744 - - 0.00000000000000000000000000867 113.0
TLS3_k127_6177601_0 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000004096 182.0
TLS3_k127_6177601_1 Penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000001236 174.0
TLS3_k127_6185776_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0 1563.0
TLS3_k127_6193765_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 5.404e-303 948.0
TLS3_k127_6193765_1 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007314 428.0
TLS3_k127_6193765_10 Rubrerythrin - - - 0.000000000000000000007484 94.0
TLS3_k127_6193765_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 413.0
TLS3_k127_6193765_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 393.0
TLS3_k127_6193765_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 326.0
TLS3_k127_6193765_5 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000814 271.0
TLS3_k127_6193765_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000000000000000000000001381 217.0
TLS3_k127_6193765_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000002402 228.0
TLS3_k127_6193765_8 Belongs to the skp family K06142 - - 0.00000000000000000000000000000000000000000000000000000001963 201.0
TLS3_k127_6193765_9 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000002388 202.0
TLS3_k127_6195232_0 ATPase components of ABC transporters with duplicated ATPase domains K15738 - - 4.209e-200 640.0
TLS3_k127_6195232_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 492.0
TLS3_k127_6195232_10 Cytochrome c K17223 - - 0.00000000000000000000001475 115.0
TLS3_k127_6195232_11 Glycine zipper 2TM domain K04062 - - 0.00000000001151 67.0
TLS3_k127_6195232_2 Major facilitator superfamily K03446,K18926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 472.0
TLS3_k127_6195232_3 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 396.0
TLS3_k127_6195232_4 PFAM Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008448 338.0
TLS3_k127_6195232_5 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 304.0
TLS3_k127_6195232_6 NnrU protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001196 252.0
TLS3_k127_6195232_7 Protein of unknown function (DUF3014) - - - 0.000000000000000000000000000000000000000000000000000000000000001403 227.0
TLS3_k127_6195232_8 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000001335 165.0
TLS3_k127_6195232_9 PFAM Thioredoxin K00384 - 1.8.1.9 0.00000000000000000000000007187 112.0
TLS3_k127_6217311_0 Phospholipase D Active site motif K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 334.0
TLS3_k127_6217311_1 Mechanosensitive ion channel K05802 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001852 251.0
TLS3_k127_6217311_2 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000002079 203.0
TLS3_k127_6223695_0 oxidase, subunit II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 347.0
TLS3_k127_6223695_1 - - - - 0.000000000000000000000000000001031 129.0
TLS3_k127_6224595_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000001003 258.0
TLS3_k127_6224595_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000004509 244.0
TLS3_k127_6224595_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000321 150.0
TLS3_k127_6224595_3 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000001036 111.0
TLS3_k127_6227528_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 2.417e-292 904.0
TLS3_k127_6227528_1 trehalohydrolase K01236 - 3.2.1.141 0.000000000000000000000000000000000000001381 150.0
TLS3_k127_6229783_0 Domain of unknown function (DUF5117) - - - 7.646e-197 636.0
TLS3_k127_6229783_1 PFAM PhoH family protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009564 429.0
TLS3_k127_6229783_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000007698 164.0
TLS3_k127_6247380_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1064.0
TLS3_k127_6247380_1 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 408.0
TLS3_k127_6247380_2 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000001927 175.0
TLS3_k127_6247380_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000001411 159.0
TLS3_k127_6247380_4 - - - - 0.0000000000000000000000000007499 123.0
TLS3_k127_6247380_5 - - - - 0.000000000000001616 78.0
TLS3_k127_6251444_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 2.371e-240 747.0
TLS3_k127_6251444_1 Homoserine dehydrogenase, NAD binding domain-containing protein - - - 6.517e-210 661.0
TLS3_k127_6251444_2 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 484.0
TLS3_k127_6251444_3 Ferritin-like K20087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 499.0
TLS3_k127_6251444_4 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000000000000058 145.0
TLS3_k127_6251444_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000000000003249 113.0
TLS3_k127_6251444_6 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.000000000000007518 74.0
TLS3_k127_6259352_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 561.0
TLS3_k127_6259352_1 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000001779 208.0
TLS3_k127_6278154_0 Flavin containing amine oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 495.0
TLS3_k127_6278154_1 Converts GTP to 7,8-dihydroneopterin triphosphate K01495,K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 336.0
TLS3_k127_6278154_2 Glutathione peroxidase K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000001173 244.0
TLS3_k127_6278154_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000004123 209.0
TLS3_k127_6278154_4 B12 binding domain K22491 - - 0.000000000000000001448 86.0
TLS3_k127_6282357_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 1.358e-205 651.0
TLS3_k127_6303063_0 TIGRFAM maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 291.0
TLS3_k127_6303063_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001673 267.0
TLS3_k127_6311646_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 572.0
TLS3_k127_6311646_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 298.0
TLS3_k127_6318868_0 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 368.0
TLS3_k127_6318868_1 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 333.0
TLS3_k127_6318868_2 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000005734 181.0
TLS3_k127_6318868_3 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.0000000000008395 75.0
TLS3_k127_6324521_0 CoA-binding domain protein K09181 - - 1.063e-247 794.0
TLS3_k127_6324521_1 Calcineurin-like phosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000078 216.0
TLS3_k127_6324521_2 TraB family K09973 - - 0.0000000000000000000000000000000000000000003225 181.0
TLS3_k127_6324521_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000001056 106.0
TLS3_k127_6324521_4 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000005956 71.0
TLS3_k127_63578_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1007.0
TLS3_k127_63578_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.23e-208 649.0
TLS3_k127_63578_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000000009963 142.0
TLS3_k127_63578_11 ATP synthase I chain K02116 - - 0.0000000000000000000000004165 109.0
TLS3_k127_63578_12 Protein involved in outer membrane biogenesis - - - 0.000000004888 68.0
TLS3_k127_63578_2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 407.0
TLS3_k127_63578_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 366.0
TLS3_k127_63578_4 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 361.0
TLS3_k127_63578_5 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000001482 205.0
TLS3_k127_63578_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000000222 192.0
TLS3_k127_63578_7 GNAT family acetyltransferase - - - 0.000000000000000000000000000000000000000000000000003433 202.0
TLS3_k127_63578_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000003252 191.0
TLS3_k127_63578_9 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000001732 174.0
TLS3_k127_6381835_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 329.0
TLS3_k127_6381835_1 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002999 276.0
TLS3_k127_6387867_0 Atp-dependent helicase K03578 - 3.6.4.13 0.0 1307.0
TLS3_k127_6387867_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions - - - 0.0000000000000000000000000000002124 127.0
TLS3_k127_6390266_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 4.317e-206 650.0
TLS3_k127_6390266_1 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 525.0
TLS3_k127_6390266_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 422.0
TLS3_k127_6390266_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 321.0
TLS3_k127_6390266_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000005306 267.0
TLS3_k127_6390266_5 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000001739 134.0
TLS3_k127_6390266_6 - - - - 0.000000000000001908 78.0
TLS3_k127_6429073_0 N-acyl-D-aspartate D-glutamate deacylase K06015 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 361.0
TLS3_k127_6429073_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 352.0
TLS3_k127_6455906_0 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 404.0
TLS3_k127_6455906_1 EamA-like transporter family K15268 - - 0.000000000000000000000000000000000000000000000006349 178.0
TLS3_k127_6456194_0 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 505.0
TLS3_k127_6456194_1 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 365.0
TLS3_k127_6456194_2 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000006276 178.0
TLS3_k127_6456194_3 acyl-coA-binding protein - - - 0.0000000000000000000000000000000005634 141.0
TLS3_k127_6456194_4 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.0000000000006265 81.0
TLS3_k127_6598233_0 Male sterility protein - - - 6.234e-221 694.0
TLS3_k127_6598233_1 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 429.0
TLS3_k127_6598233_2 Bacterial transcriptional repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 314.0
TLS3_k127_6598233_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000007006 176.0
TLS3_k127_6598233_4 PFAM poly granule associated family protein - - - 0.00000000000000000000000000000000002173 141.0
TLS3_k127_6608840_0 - - - - 0.000000000000000000000000000000000000000000000000000000000001314 232.0
TLS3_k127_6608840_1 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000005036 161.0
TLS3_k127_6630571_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 403.0
TLS3_k127_6630571_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 355.0
TLS3_k127_6630571_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000001052 221.0
TLS3_k127_6630571_3 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000001346 211.0
TLS3_k127_6630571_4 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000000004353 179.0
TLS3_k127_6630571_5 Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000007381 146.0
TLS3_k127_6728568_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 6.065e-194 614.0
TLS3_k127_6728568_1 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000008486 166.0
TLS3_k127_6728568_2 - - - - 0.000006201 51.0
TLS3_k127_6744818_0 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 375.0
TLS3_k127_6744818_1 Serine hydrolase (FSH1) K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 292.0
TLS3_k127_6744818_2 PFAM DoxX family protein K15977 - - 0.00000000000000000000000000000000000000006413 154.0
TLS3_k127_6744818_3 Molybdenum cofactor synthesis domain K03831 - 2.7.7.75 0.000000000000000952 76.0
TLS3_k127_676827_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 520.0
TLS3_k127_676827_1 O-Antigen ligase - - - 0.000000000000000000000000000004183 124.0
TLS3_k127_6791043_0 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 490.0
TLS3_k127_6791043_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 446.0
TLS3_k127_6791043_2 Belongs to the ABC transporter superfamily K02031,K16202 - - 0.0000000000000000000000000000000000000000000000000000006069 197.0
TLS3_k127_6791043_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000392 126.0
TLS3_k127_6807413_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009725 446.0
TLS3_k127_6807413_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 371.0
TLS3_k127_6807413_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 336.0
TLS3_k127_6807413_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 335.0
TLS3_k127_6807413_4 Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers K07518 - 3.1.1.22 0.000000000000000000000000000000000000003874 148.0
TLS3_k127_6861246_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001181 282.0
TLS3_k127_6861246_1 Lysophospholipase L1 and related esterases K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000005052 247.0
TLS3_k127_6861246_2 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.0000000000000000000000000000000000000000000002476 177.0
TLS3_k127_6898962_0 DNA helicase K03654 - 3.6.4.12 5.656e-225 721.0
TLS3_k127_6898962_1 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 9.241e-220 697.0
TLS3_k127_6898962_10 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 291.0
TLS3_k127_6898962_11 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001349 237.0
TLS3_k127_6898962_12 Protein of unknown function (DUF3455) - - - 0.00000000000000000000000000000000000000000000000000000005647 203.0
TLS3_k127_6898962_13 Putative sugar-binding N-terminal domain K21948 - 2.7.1.217 0.00000000000000000000000000000000000000000000000000002468 195.0
TLS3_k127_6898962_14 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000003656 192.0
TLS3_k127_6898962_15 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000001351 180.0
TLS3_k127_6898962_16 Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000000000000000000000000009472 184.0
TLS3_k127_6898962_17 - - - - 0.0000000000000000000000000000000000000000002179 170.0
TLS3_k127_6898962_19 Helix-turn-helix domain - - - 0.00000000000000000000000000000000001403 154.0
TLS3_k127_6898962_2 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 5.87e-217 677.0
TLS3_k127_6898962_20 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000001457 141.0
TLS3_k127_6898962_21 ASCH - - - 0.00000000000000000000000004426 120.0
TLS3_k127_6898962_22 YtkA-like - - - 0.000000000000000000000004443 107.0
TLS3_k127_6898962_23 - - - - 0.00000000000000000000003436 104.0
TLS3_k127_6898962_24 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000003965 105.0
TLS3_k127_6898962_25 membrane - - - 0.0000000000001296 76.0
TLS3_k127_6898962_3 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 553.0
TLS3_k127_6898962_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007936 512.0
TLS3_k127_6898962_5 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 486.0
TLS3_k127_6898962_6 Zn-dependent hydrolases including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 442.0
TLS3_k127_6898962_7 Cys/Met metabolism PLP-dependent enzyme K01760 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 403.0
TLS3_k127_6898962_8 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007314 338.0
TLS3_k127_6898962_9 Flavin-binding monooxygenase-like K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 344.0
TLS3_k127_6901331_0 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 526.0
TLS3_k127_6903852_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 319.0
TLS3_k127_6914044_0 response regulator receiver K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 293.0
TLS3_k127_6914044_1 methyltransferase activity K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000008717 231.0
TLS3_k127_6961424_0 Flotillin - - - 1.628e-227 717.0
TLS3_k127_6961424_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000706 535.0
TLS3_k127_6961424_2 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 528.0
TLS3_k127_6961424_3 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 431.0
TLS3_k127_6961424_4 Phosphoenolpyruvate hydrolase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 394.0
TLS3_k127_6961424_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000007138 241.0
TLS3_k127_6961424_6 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000008653 138.0
TLS3_k127_6986589_0 Dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 524.0
TLS3_k127_6986589_1 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000003292 186.0
TLS3_k127_6991594_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1131.0
TLS3_k127_6991594_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 398.0
TLS3_k127_7008796_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 507.0
TLS3_k127_7008796_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 466.0
TLS3_k127_7008796_10 Zinc-finger domain - - - 0.000000000000000003529 97.0
TLS3_k127_7008796_2 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 377.0
TLS3_k127_7008796_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 393.0
TLS3_k127_7008796_4 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 304.0
TLS3_k127_7008796_5 branched-chain amino acid permease (azaleucine resistance) - - - 0.00000000000000000000000000000000000000000000000000000000000989 230.0
TLS3_k127_7008796_6 phosphohydrolase - - - 0.000000000000000000000000000000000000000000008887 174.0
TLS3_k127_7008796_7 SnoaL-like domain - - - 0.000000000000000000000000000000216 131.0
TLS3_k127_7008796_8 Protein of unknown function (DUF2946) - - - 0.00000000000000000000128 99.0
TLS3_k127_7008796_9 Branched-chain amino acid transport protein (AzlD) - - - 0.000000000000000001429 98.0
TLS3_k127_7017435_0 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 356.0
TLS3_k127_7017435_1 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000001624 238.0
TLS3_k127_7017435_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004365 244.0
TLS3_k127_7017435_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000004528 134.0
TLS3_k127_7027765_0 COG3267 Type II secretory pathway, component ExeA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 362.0
TLS3_k127_7027765_1 AAA domain K08252,K16692 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005618 287.0
TLS3_k127_7027765_2 polysaccharide deactylase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001985 238.0
TLS3_k127_7027765_3 Polysaccharide chain length determinant protein - - - 0.00000000000000000000000000000000000000000000000000000000001447 214.0
TLS3_k127_7036512_0 Adenylate cyclase - - - 2.185e-224 713.0
TLS3_k127_7036512_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 444.0
TLS3_k127_7036512_2 Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 402.0
TLS3_k127_7036512_3 Peptidase, M23 - - - 0.00000000000000000000000000000000000000000000000000000004858 201.0
TLS3_k127_7036512_4 Cupin 2, conserved barrel domain protein - - - 0.0003157 46.0
TLS3_k127_7040093_0 COG3121 P pilus assembly protein, chaperone PapD K07346 - - 0.0000000000000000000000000307 117.0
TLS3_k127_7040093_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000009107 111.0
TLS3_k127_7040093_2 Spore Coat Protein U domain - - - 0.00000000000000000000007676 104.0
TLS3_k127_7040093_3 Secreted protein - - - 0.00000000000005071 79.0
TLS3_k127_7040093_4 - - - - 0.0000000000005343 76.0
TLS3_k127_7040880_0 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 444.0
TLS3_k127_7040880_1 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000304 256.0
TLS3_k127_7040880_2 mandelate racemase muconate lactonizing K01706 - 4.2.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000001845 239.0
TLS3_k127_7068377_0 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 596.0
TLS3_k127_7068377_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 563.0
TLS3_k127_7068377_2 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 387.0
TLS3_k127_7068377_3 Belongs to the DapB family K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 339.0
TLS3_k127_7068377_4 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002263 237.0
TLS3_k127_7068377_5 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004014 234.0
TLS3_k127_7068377_6 glutamate--cysteine ligase K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000001666 206.0
TLS3_k127_7068377_7 pts system fructose subfamily IIa component K02821 - 2.7.1.194 0.000000000000000000000000000000000579 145.0
TLS3_k127_7068377_8 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000006807 128.0
TLS3_k127_7068377_9 phosphocarrier, HPr family K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000006212 120.0
TLS3_k127_7106328_0 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 364.0
TLS3_k127_7106328_1 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 353.0
TLS3_k127_7106328_2 VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001187 258.0
TLS3_k127_7106328_3 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000177 215.0
TLS3_k127_7106328_4 MlaC protein K07323 - - 0.0000000000000001583 86.0
TLS3_k127_7131867_0 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 381.0
TLS3_k127_7131867_1 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001772 261.0
TLS3_k127_7131867_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000004252 167.0
TLS3_k127_7131867_3 Protein of unknown function (DUF1178) - - - 0.0000000000000000000000000000000000000002967 154.0
TLS3_k127_7132882_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 574.0
TLS3_k127_7132882_1 helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 550.0
TLS3_k127_7132882_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002498 269.0
TLS3_k127_7132882_3 - - - - 0.000000000000000000000000000000000000000000000000000000002988 216.0
TLS3_k127_7132882_4 GCN5-related N-acetyl-transferase K06975 - - 0.000000000000000000000006174 104.0
TLS3_k127_7132882_5 Protein of unknown function (DUF1059) - - - 0.00000000000000000000004446 102.0
TLS3_k127_7136498_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 367.0
TLS3_k127_7136498_1 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000003359 211.0
TLS3_k127_7136498_2 Protein of unknown function (DUF2788) - - - 0.00000000000000000000001001 101.0
TLS3_k127_7176874_0 Extracellular solute-binding protein, family 5 middle family protein 22 - - - 8.13e-295 923.0
TLS3_k127_7176874_1 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 572.0
TLS3_k127_7176874_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 419.0
TLS3_k127_7176874_3 MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000007498 218.0
TLS3_k127_7176874_4 thioesterase K07107 - - 0.0000000000000000000000000000000000000004504 158.0
TLS3_k127_7176874_5 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 0.000000000000002923 89.0
TLS3_k127_7183582_0 Extracellular liganD-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 584.0
TLS3_k127_7183582_1 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 291.0
TLS3_k127_7195984_0 Acyl-CoA dehydrogenase, C-terminal domain K19966 - 3.13.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 434.0
TLS3_k127_7195984_1 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000001068 129.0
TLS3_k127_7195984_2 PRC-barrel domain - - - 0.0000000008496 70.0
TLS3_k127_7205772_0 Aminotransferase K14287 - 2.6.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 513.0
TLS3_k127_7205772_1 Zn_pept - - - 0.00000000000000000000000000000000009778 138.0
TLS3_k127_7217191_0 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 458.0
TLS3_k127_7217191_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000002246 237.0
TLS3_k127_7217191_2 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848,K20906 - 5.4.99.2,5.4.99.64 0.0000000000000000000000000000004619 127.0
TLS3_k127_7247146_0 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 349.0
TLS3_k127_7247146_1 PFAM VanZ family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000012 279.0
TLS3_k127_7247146_2 Alpha beta K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000892 247.0
TLS3_k127_7247146_3 Ferredoxin - - - 0.00000000000000000000000000000000000000004683 168.0
TLS3_k127_7247146_4 Aminotransferase class IV K00824 - 2.6.1.21 0.000000000000000000000000000000000000001183 156.0
TLS3_k127_7247146_5 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.000000000000000000000000000000000000005975 157.0
TLS3_k127_7247146_6 - - - - 0.0000000000002005 78.0
TLS3_k127_7254091_0 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 533.0
TLS3_k127_7254091_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 467.0
TLS3_k127_7254091_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 413.0
TLS3_k127_7254091_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000001718 158.0
TLS3_k127_7280405_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 405.0
TLS3_k127_7280405_1 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000003011 177.0
TLS3_k127_7280405_2 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000002785 151.0
TLS3_k127_7280405_3 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000000000000000000000000005871 135.0
TLS3_k127_7284811_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 5.692e-318 1007.0
TLS3_k127_7325539_0 two-component system sensor protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000101 299.0
TLS3_k127_7325539_1 Cysteine-rich CWC - - - 0.000005128 56.0
TLS3_k127_7334222_0 alcohol dehydrogenase K19745 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 424.0
TLS3_k127_7334222_1 Flavin containing amine oxidoreductase K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 378.0
TLS3_k127_7334222_2 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000211 230.0
TLS3_k127_7388116_0 CoA-transferase family III K18289 - 2.8.3.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 514.0
TLS3_k127_7388116_1 MmgE PrpD family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 366.0
TLS3_k127_7417253_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 573.0
TLS3_k127_7417253_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 400.0
TLS3_k127_7417253_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 391.0
TLS3_k127_7417253_3 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 391.0
TLS3_k127_7417253_4 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 338.0
TLS3_k127_7417253_5 toluene tolerance K07323 - - 0.0000000000000000000000000000000000000000000000000000000000432 208.0
TLS3_k127_7417253_6 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000001048 124.0
TLS3_k127_7417253_7 STAS domain K07122 - - 0.00000000001037 68.0
TLS3_k127_7447522_0 Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single strand break in duplex DNA K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 2.503e-216 689.0
TLS3_k127_7447522_1 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.000000000000000000000000000000000000001769 164.0
TLS3_k127_7447522_2 - - - - 0.000000000000000000002895 96.0
TLS3_k127_7467833_0 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 4.451e-225 705.0
TLS3_k127_7467833_1 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.00000000000000000000000000000000000000000000005206 175.0
TLS3_k127_7516186_0 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 354.0
TLS3_k127_7516186_1 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000005964 213.0
TLS3_k127_7516186_2 - - - - 0.000000000004377 75.0
TLS3_k127_7516186_3 - - - - 0.0000000478 61.0
TLS3_k127_753367_0 Dynamin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009014 458.0
TLS3_k127_753367_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 302.0
TLS3_k127_7572643_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000171 160.0
TLS3_k127_7572643_1 PFAM Sporulation domain protein - - - 0.0000000000000000102 92.0
TLS3_k127_7602843_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 2.252e-197 627.0
TLS3_k127_7602843_1 Cyclase dehydrase - - - 0.00000000000000000000000000000000004871 139.0
TLS3_k127_7602843_2 ATP synthase subunit D K02120 - - 0.0000000000000000000000000000000004956 144.0
TLS3_k127_7602843_3 PFAM cytochrome c, class I K08738 - - 0.000000000000002702 79.0
TLS3_k127_7602843_4 PFAM cytochrome c, class I K08738 - - 0.0003054 47.0
TLS3_k127_7639695_0 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 391.0
TLS3_k127_7639695_1 ROK family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 327.0
TLS3_k127_7671514_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 419.0
TLS3_k127_7671514_1 methyltransferase activity K00563,K13307,K13330,K15256 - 2.1.1.187,2.1.1.235,2.1.1.324 0.0000000000000000000000000000000000000000000000000000000000000000000000005611 253.0
TLS3_k127_7671514_2 transcriptional Regulator, LysR family - - - 0.0000000000000000000000000000000000005023 145.0
TLS3_k127_7671514_3 Permeases of the drug metabolite transporter (DMT) superfamily K12962 - - 0.0000000000006263 73.0
TLS3_k127_7671514_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000005064 62.0
TLS3_k127_76772_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.057e-295 924.0
TLS3_k127_76772_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.628e-199 645.0
TLS3_k127_76772_2 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 320.0
TLS3_k127_76772_3 Phosphoribosyl transferase domain K07101 - - 0.00000000000000000000000000000000000000000000000000000000000000000001099 243.0
TLS3_k127_7741716_0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 375.0
TLS3_k127_7741716_1 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 314.0
TLS3_k127_7741716_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001739 258.0
TLS3_k127_7741716_3 MotA/TolQ/ExbB proton channel family - - - 0.000000000000000000000000000000000000000000000000000004731 192.0
TLS3_k127_7741716_4 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000000000000007105 191.0
TLS3_k127_7741716_5 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000000000000001222 181.0
TLS3_k127_7741716_6 Lecithin retinol acyltransferase - - - 0.00000000000000000000000000000000000000003198 160.0
TLS3_k127_7774270_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 2.447e-195 623.0
TLS3_k127_7774270_1 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006482 582.0
TLS3_k127_7774270_2 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 298.0
TLS3_k127_7774270_3 TIGRFAM 2-aminoethylphosphonate ABC transport system, 1-aminoethylphosphonate-binding protein component K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000001022 237.0
TLS3_k127_77753_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000122 247.0
TLS3_k127_77753_1 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000005559 117.0
TLS3_k127_77753_2 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000003859 79.0
TLS3_k127_77753_3 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme - - - 0.00000001037 66.0
TLS3_k127_77753_4 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000004122 63.0
TLS3_k127_7781347_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 3.568e-245 775.0
TLS3_k127_7781347_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 470.0
TLS3_k127_7781347_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000001573 272.0
TLS3_k127_7781347_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000001141 246.0
TLS3_k127_7781347_4 - - - - 0.0000000000000000000000000000000000000000000000001822 184.0
TLS3_k127_7781347_5 PFAM transport-associated - - - 0.000000000000000000000000000000000000000002746 166.0
TLS3_k127_7781347_6 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000000302 143.0
TLS3_k127_7781347_7 LppC putative lipoprotein K07121 - - 0.000000000000000000000000000000001099 146.0
TLS3_k127_7781347_8 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000004403 116.0
TLS3_k127_7804477_0 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 541.0
TLS3_k127_7804477_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 546.0
TLS3_k127_7804477_2 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 507.0
TLS3_k127_7804477_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 439.0
TLS3_k127_7804477_4 abc transporter K02003,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 340.0
TLS3_k127_7804477_5 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 339.0
TLS3_k127_7804477_6 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000288 225.0
TLS3_k127_7804477_7 Pyridoxamine 5'-phosphate oxidase like - - - 0.000000000000000000000000000004345 126.0
TLS3_k127_7804477_8 His Kinase A (phosphoacceptor) domain - - - 0.0000000000001215 84.0
TLS3_k127_7804477_9 Protein of unknown function (DUF1439) - - - 0.0002837 50.0
TLS3_k127_7813730_0 COG3454 Metal-dependent hydrolase involved in phosphonate metabolism K06162 - 3.6.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 366.0
TLS3_k127_7813730_1 Protein of unknown function (DUF1045) - - - 0.000000000000000000000000000000000000000000000003823 188.0
TLS3_k127_7828476_0 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000005476 150.0
TLS3_k127_7828476_1 cell adhesion K20276 - - 0.0000000000000000000002066 111.0
TLS3_k127_7828476_2 serine threonine protein kinase - - - 0.0000000000000009141 79.0
TLS3_k127_7844213_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 1.35e-218 686.0
TLS3_k127_7844213_1 Protein of unknown function (DUF3579) - - - 0.0000000000000000000000002383 108.0
TLS3_k127_7845812_0 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 333.0
TLS3_k127_7845812_1 Disulfide bond isomerase protein N-terminus K03981 - 5.3.4.1 0.00000000000000000005663 95.0
TLS3_k127_7845812_2 YXWGXW repeat (2 copies) - - - 0.000000000000000006309 88.0
TLS3_k127_7845812_3 Isochorismatase family - - - 0.00000000000000003649 82.0
TLS3_k127_7845812_4 Belongs to the 'phage' integrase family - - - 0.00001857 47.0
TLS3_k127_7847678_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 531.0
TLS3_k127_7847678_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001789 273.0
TLS3_k127_7847678_2 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000002032 256.0
TLS3_k127_7847678_3 Peptidase family M48 - - - 0.00000000000000000000000000002967 125.0
TLS3_k127_7848587_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009677 291.0
TLS3_k127_7848587_1 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.00000000000000000000000000005077 128.0
TLS3_k127_7850707_0 Peptidase family M3 K01392 - 3.4.24.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 566.0
TLS3_k127_7850707_1 Adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005126 279.0
TLS3_k127_7850707_2 FAD linked oxidases, C-terminal domain K00102,K03777 - 1.1.2.4,1.1.5.12 0.0000000000000000000000000000000000000000000000000000000000001087 221.0
TLS3_k127_7861329_0 FtsX-like permease family K02004 - - 9.041e-223 724.0
TLS3_k127_7861329_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 541.0
TLS3_k127_7861329_2 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 400.0
TLS3_k127_7861329_3 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005348 263.0
TLS3_k127_7861329_4 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000001968 189.0
TLS3_k127_7861329_5 MAPEG family - - - 0.000000000000000000000000000000008678 145.0
TLS3_k127_7861329_6 enzyme binding - - - 0.0000000000000000000000001499 117.0
TLS3_k127_7861329_7 ABC transporter transmembrane region K06147 - - 0.000000000000000000255 90.0
TLS3_k127_7871366_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 385.0
TLS3_k127_7871366_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000005755 201.0
TLS3_k127_7871366_2 type IV pilus secretin PilQ K02666 - - 0.000000000000000000000000000000000002601 139.0
TLS3_k127_7871366_3 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000001251 85.0
TLS3_k127_7876855_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 357.0
TLS3_k127_7876855_1 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000003516 186.0
TLS3_k127_7876855_2 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000001002 162.0
TLS3_k127_7891480_0 Domain of unknown function (DUF3482) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 538.0
TLS3_k127_7891480_1 Alpha beta hydrolase K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000001986 232.0
TLS3_k127_7891480_2 Domain of unknown function (DUF1840) - - - 0.000000000000000005527 87.0
TLS3_k127_7896145_0 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 505.0
TLS3_k127_7896145_1 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000694 269.0
TLS3_k127_7901634_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 574.0
TLS3_k127_7901634_1 ABC-type branched-chain amino acid transport systems periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 528.0
TLS3_k127_7901634_10 Bacterial regulatory proteins, luxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000004971 241.0
TLS3_k127_7901634_11 PFAM cytochrome c, class I K08738 - - 0.0000005972 53.0
TLS3_k127_7901634_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 394.0
TLS3_k127_7901634_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 364.0
TLS3_k127_7901634_4 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 353.0
TLS3_k127_7901634_5 Histidine kinase K20975 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 343.0
TLS3_k127_7901634_6 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 305.0
TLS3_k127_7901634_7 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 291.0
TLS3_k127_7901634_8 PFAM peptidase U61, LD-carboxypeptidase A K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006351 277.0
TLS3_k127_7901634_9 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000003331 237.0
TLS3_k127_7909470_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 2.657e-213 680.0
TLS3_k127_7909470_1 - - - - 0.0000000000000000000001143 104.0
TLS3_k127_7909470_2 methylglyoxal synthase K01734 - 4.2.3.3 0.00000007043 56.0
TLS3_k127_7920392_0 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005314 580.0
TLS3_k127_7920392_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 406.0
TLS3_k127_7920392_2 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000172 172.0
TLS3_k127_7920392_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000001961 76.0
TLS3_k127_7927795_0 Sugar transferase, PEP-CTERM EpsH1 system associated - - - 0.00000000000000000000000000000000000000000000000000000000003764 217.0
TLS3_k127_7927795_1 TPR repeat - - - 0.000000000000000000000000000000222 140.0
TLS3_k127_7950397_0 Fumarate reductase flavoprotein C-term K00244 - 1.3.5.4 0.0 1026.0
TLS3_k127_7950397_1 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 1.091e-247 771.0
TLS3_k127_7950397_2 fumarate reductase respiratory complex transmembrane subunit K00246 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 326.0
TLS3_k127_7957923_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 444.0
TLS3_k127_7957923_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 391.0
TLS3_k127_7957923_2 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 289.0
TLS3_k127_7963483_0 D-amino acid K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 503.0
TLS3_k127_7963483_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 481.0
TLS3_k127_7963483_10 Putative FMN-binding domain K07734 - - 0.0000000000000000000000000000000000000000001927 183.0
TLS3_k127_7963483_11 Cytochrome K08738 - - 0.000000000000000000000000000000001572 132.0
TLS3_k127_7963483_12 - - - - 0.00000000000131 71.0
TLS3_k127_7963483_13 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000002742 59.0
TLS3_k127_7963483_2 amino acid K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 462.0
TLS3_k127_7963483_3 oxidoreductase FAD NAD(P)-binding domain protein K00523,K18248 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 463.0
TLS3_k127_7963483_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 439.0
TLS3_k127_7963483_5 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 391.0
TLS3_k127_7963483_6 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 365.0
TLS3_k127_7963483_7 abc transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008059 363.0
TLS3_k127_7963483_8 RmlD substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 317.0
TLS3_k127_7963483_9 Acetyltransferase (GNAT) domain K03829 - - 0.00000000000000000000000000000000000000000000000000000000000000009527 224.0
TLS3_k127_7968140_0 phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 356.0
TLS3_k127_7968140_1 very-long-chain-acyl-CoA dehydrogenase activity K17880,K18817 - 2.7.1.119,2.7.1.163 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006011 335.0
TLS3_k127_7968140_2 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000005474 118.0
TLS3_k127_7976914_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 4.907e-247 780.0
TLS3_k127_7976914_1 Peptidase C39 family K13409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005985 440.0
TLS3_k127_7976914_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003401 278.0
TLS3_k127_7976914_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000001471 178.0
TLS3_k127_7976914_4 AAA ATPase domain - - - 0.00000000009894 69.0
TLS3_k127_7977509_0 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 294.0
TLS3_k127_7977509_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000008863 192.0
TLS3_k127_7978475_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 1.275e-222 702.0
TLS3_k127_7978475_1 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000000008163 197.0
TLS3_k127_7978475_2 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000007408 156.0
TLS3_k127_7993615_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1350.0
TLS3_k127_7998864_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 283.0
TLS3_k127_7998864_1 - - - - 0.0000000000000000000000000000000000003441 153.0
TLS3_k127_8023901_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 7.993e-239 743.0
TLS3_k127_8023901_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 463.0
TLS3_k127_8025490_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 484.0
TLS3_k127_8025490_1 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 414.0
TLS3_k127_8025490_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 366.0
TLS3_k127_8025490_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001278 276.0
TLS3_k127_8025490_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000006893 184.0
TLS3_k127_8025490_5 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000003356 186.0
TLS3_k127_8025490_6 Putative serine dehydratase domain K18425 - 4.1.3.41 0.0000000000000000000000000000001784 127.0
TLS3_k127_8025490_7 Domain of Unknown Function (DUF350) K08989 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000002101 74.0
TLS3_k127_8026546_0 orn lys arg decarboxylase K01584 - 4.1.1.19 0.0 1245.0
TLS3_k127_8026546_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 1.207e-245 772.0
TLS3_k127_8026546_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 492.0
TLS3_k127_8026546_3 Beta-eliminating lyase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 449.0
TLS3_k127_8026546_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000001665 162.0
TLS3_k127_8034321_0 Peptidase M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 519.0
TLS3_k127_8034321_1 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 421.0
TLS3_k127_8034321_2 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 333.0
TLS3_k127_8034321_3 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007888 263.0
TLS3_k127_8040944_0 O-Methyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 306.0
TLS3_k127_8040944_1 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.0000000000000000000000000000000000000000000000001296 187.0
TLS3_k127_8040944_2 rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000000000000005387 162.0
TLS3_k127_8040944_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00002419 46.0
TLS3_k127_8052901_0 translation release factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 364.0
TLS3_k127_8052901_1 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.00000000000000000000000000000000000000000000000000000000000000000008919 243.0
TLS3_k127_8052901_2 RF-1 domain K15034 - - 0.000000000000000000000000000000004556 130.0
TLS3_k127_8052901_3 regulation of translation K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.000000001473 61.0
TLS3_k127_8069220_0 Malonate decarboxylase, alpha subunit, transporter K01026 - 2.8.3.1 3.728e-309 968.0
TLS3_k127_8069220_1 COG1247 Sortase and related acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000008194 214.0
TLS3_k127_8069220_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000008726 144.0
TLS3_k127_8092694_0 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 446.0
TLS3_k127_8092694_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 377.0
TLS3_k127_8092694_2 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.00000000000000000000000000000000000000000000000001725 181.0
TLS3_k127_8096125_0 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 601.0
TLS3_k127_8096125_1 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000001533 159.0
TLS3_k127_8096125_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000003819 71.0
TLS3_k127_80998_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 7.879e-198 634.0
TLS3_k127_80998_1 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 503.0
TLS3_k127_80998_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 478.0
TLS3_k127_80998_3 Major facilitator superfamily K07552,K18552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 319.0
TLS3_k127_80998_4 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001481 261.0
TLS3_k127_80998_5 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000001886 237.0
TLS3_k127_80998_6 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000334 182.0
TLS3_k127_80998_7 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000002121 155.0
TLS3_k127_80998_8 transporter K05786 - - 0.0000000000000000000000000002526 115.0
TLS3_k127_8112735_0 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 2.009e-208 656.0
TLS3_k127_8112735_1 Disulphide bond corrector protein DsbC K04084,K08344 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 548.0
TLS3_k127_8112735_2 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000006971 201.0
TLS3_k127_8112735_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000448 164.0
TLS3_k127_8112735_4 Redoxin - - - 0.00000000000000000000004111 101.0
TLS3_k127_8139397_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 1.682e-242 762.0
TLS3_k127_8145021_0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 415.0
TLS3_k127_8145021_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016740,GO:0017013,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0031975,GO:0036094,GO:0036211,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:0098552,GO:0098567,GO:1901265,GO:1901363,GO:1901564 2.7.1.180 0.00000000000000000000000000000000001779 147.0
TLS3_k127_8145021_2 PFAM CBS domain containing protein - - - 0.000000000000000000000004287 107.0
TLS3_k127_8153846_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 447.0
TLS3_k127_8153846_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 415.0
TLS3_k127_8153846_2 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000001282 209.0
TLS3_k127_8201612_0 N-acetyltransferase K00675 - 2.3.1.118 0.000000000000000000000000000000000000000000000000000000000000000005157 234.0
TLS3_k127_8201612_1 Histidine kinase K02030 - - 0.00000000000000001276 87.0
TLS3_k127_8201612_2 Elongation factor K06140 - - 0.00000001029 61.0
TLS3_k127_8220727_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 424.0
TLS3_k127_8220727_1 methylglyoxal synthase K01734 - 4.2.3.3 0.0000000000000000000000000000000000000000000004195 168.0
TLS3_k127_8220727_2 Zn-ribbon protein possibly nucleic acid-binding - - - 0.00000000000000000003104 95.0
TLS3_k127_8272740_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 1.147e-217 704.0
TLS3_k127_8272740_1 Aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 468.0
TLS3_k127_8272740_2 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 447.0
TLS3_k127_8272740_3 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 315.0
TLS3_k127_8272740_4 Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000009028 212.0
TLS3_k127_8273131_0 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 464.0
TLS3_k127_8273131_1 PD-(D/E)XK nuclease superfamily K01144 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 360.0
TLS3_k127_8278693_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 562.0
TLS3_k127_8278693_1 Carbon-nitrogen hydrolase K01501,K11206 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000002346 186.0
TLS3_k127_8289525_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 519.0
TLS3_k127_8289525_1 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 415.0
TLS3_k127_8289525_2 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001079 267.0
TLS3_k127_8289525_3 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000000006628 205.0
TLS3_k127_8289525_4 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000002445 141.0
TLS3_k127_8289525_5 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000002521 140.0
TLS3_k127_8289525_6 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000000000004616 135.0
TLS3_k127_8369840_0 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 325.0
TLS3_k127_8369840_1 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000000000000001882 207.0
TLS3_k127_8369840_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000002044 139.0
TLS3_k127_8370102_0 PFAM glycosyl transferase group 1 K02844,K14335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 311.0
TLS3_k127_8370102_1 Uncharacterized protein conserved in bacteria (DUF2334) K06986 - - 0.00000000000000000000000000000000000000000000000000000000000000008752 233.0
TLS3_k127_8370102_2 Domain of unknown function (DUF2383) - - - 0.000000000000000000000000000000000000000000001053 172.0
TLS3_k127_8370102_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000001944 166.0
TLS3_k127_8370102_4 - - - - 0.0000000000000000001784 96.0
TLS3_k127_8370102_5 Domain of unknown function (DUF305) K08995 - - 0.000000000000001633 87.0
TLS3_k127_8370102_6 - - - - 0.0000257 55.0
TLS3_k127_8401333_0 NlpB/DapX lipoprotein K07287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 356.0
TLS3_k127_8401333_1 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007013 258.0
TLS3_k127_8401333_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000007321 117.0
TLS3_k127_8419104_0 DNA recombination protein, rmuC K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 469.0
TLS3_k127_8419104_1 short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000582 167.0
TLS3_k127_8419104_2 membrane protein of uknown function UCP014873 - - - 0.00000000000000000000000000000000000000007986 162.0
TLS3_k127_8437143_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 393.0
TLS3_k127_8437143_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 318.0
TLS3_k127_8437143_2 Sporulation domain protein K03749 - - 0.00000000000000000000000000008493 125.0
TLS3_k127_8437143_3 Colicin V production protein K03558 - - 0.0000000000000007673 84.0
TLS3_k127_8471608_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 378.0
TLS3_k127_8471608_1 PFAM Rhomboid family protein - - - 0.0000000000000000000000000000000000000000000000000000000002457 218.0
TLS3_k127_8496450_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 296.0
TLS3_k127_8496450_1 Tricorn protease C1 domain K03797 - 3.4.21.102 0.000000000000000000000000000000000006933 153.0
TLS3_k127_8503167_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 352.0
TLS3_k127_8503167_1 Histidine kinase - - - 0.000000000004529 77.0
TLS3_k127_8541973_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 490.0
TLS3_k127_8541973_1 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 400.0
TLS3_k127_8541973_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 349.0
TLS3_k127_8541973_3 squalene synthase HpnC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 329.0
TLS3_k127_8541973_4 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001814 275.0
TLS3_k127_8541973_5 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000005058 106.0
TLS3_k127_8550714_0 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 471.0
TLS3_k127_8550714_1 Phosphate transport system permease protein K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000557 422.0
TLS3_k127_8550714_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 431.0
TLS3_k127_8550714_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 404.0
TLS3_k127_8550714_4 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657,K07664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000195 278.0
TLS3_k127_8550714_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000009492 235.0
TLS3_k127_8550714_6 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000008611 105.0
TLS3_k127_8550714_7 - - - - 0.000001012 55.0
TLS3_k127_861697_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.265e-286 888.0
TLS3_k127_861697_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 553.0
TLS3_k127_861697_2 Sodium:solute symporter family K14392 - - 0.000000000000000000000000000000000000000000003008 167.0
TLS3_k127_861697_3 - - - - 0.000000000000000000000000000000000002282 153.0
TLS3_k127_86350_0 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 586.0
TLS3_k127_86350_1 3'-5' exonuclease K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 397.0
TLS3_k127_86350_2 RNA polymerase sigma factor RpoS K03087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 343.0
TLS3_k127_86350_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000291 235.0
TLS3_k127_86350_4 peptidase K06194 - - 0.00000000000000000000000000000000000000000000000000000000002725 216.0
TLS3_k127_86350_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000002327 154.0
TLS3_k127_86350_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000077 77.0
TLS3_k127_86788_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 422.0
TLS3_k127_86788_1 Uncharacterised nucleotidyltransferase - - - 0.000000000000000003335 91.0
TLS3_k127_86788_2 COG2104 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.0000000000000004355 88.0
TLS3_k127_86788_3 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.000000000004607 66.0
TLS3_k127_869799_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 372.0
TLS3_k127_869799_1 Predicted membrane protein (DUF2238) K08984 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 288.0
TLS3_k127_869799_2 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000003095 238.0
TLS3_k127_869799_3 nucleotidyltransferase activity - - - 0.00004683 51.0
TLS3_k127_875647_0 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 449.0
TLS3_k127_875647_1 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004246 269.0
TLS3_k127_877572_0 UPF0365 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 495.0
TLS3_k127_877572_1 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 441.0
TLS3_k127_879269_0 ABC transporter K06020 - 3.6.3.25 2.456e-289 895.0
TLS3_k127_879269_1 sulfatase - - - 5.46e-231 734.0
TLS3_k127_879269_2 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000007138 174.0
TLS3_k127_879269_3 Uncharacterized protein family UPF0016 - - - 0.00000000000335 67.0
TLS3_k127_879979_0 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 357.0
TLS3_k127_879979_1 PFAM UBA THIF-type NAD FAD binding protein K22132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001088 280.0
TLS3_k127_879979_2 major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004275 272.0
TLS3_k127_879979_3 of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001192 217.0
TLS3_k127_879979_4 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.00000000000000000000000000000000000000000000000000000000004458 212.0
TLS3_k127_879979_5 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000007392 176.0
TLS3_k127_879979_6 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.00000000000001883 80.0
TLS3_k127_887781_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 305.0
TLS3_k127_887781_1 Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 287.0
TLS3_k127_887781_2 Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02403 - - 0.0000000000000000000000000000002278 127.0
TLS3_k127_887781_3 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.0000000000000000000001053 112.0
TLS3_k127_887781_4 Flagellar protein FliT K02423 - - 0.0000000000153 73.0
TLS3_k127_887781_5 protein phosphatase 2C domain protein - - - 0.0002708 49.0
TLS3_k127_903173_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 5.805e-317 977.0
TLS3_k127_903173_1 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K13896,K15583 - - 2.63e-221 701.0
TLS3_k127_903173_2 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 481.0
TLS3_k127_903173_3 RNA polymerase K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006657 275.0
TLS3_k127_903173_4 - - - - 0.00000000000000000000000000000000000000000000000003195 188.0
TLS3_k127_903173_5 RDD family - - - 0.00000000000000000000000000004274 122.0
TLS3_k127_903173_6 Protein of unknown function (DUF3106) - - - 0.0000000000000000000002261 106.0
TLS3_k127_903173_7 Protein of unknown function (DUF3619) - - - 0.0000000000000003718 87.0
TLS3_k127_904569_0 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 564.0
TLS3_k127_904569_1 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006342 494.0
TLS3_k127_908508_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 415.0
TLS3_k127_908508_1 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008407 241.0
TLS3_k127_908508_2 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000009873 184.0
TLS3_k127_908508_3 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.00000000000000000000000000000000000000000000000001229 185.0
TLS3_k127_911010_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007486 443.0
TLS3_k127_911010_1 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 295.0
TLS3_k127_919511_0 Outer membrane usher protein K07347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 314.0
TLS3_k127_919511_1 Spore Coat Protein U domain - - - 0.00000000001161 77.0
TLS3_k127_921459_0 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 314.0
TLS3_k127_921459_1 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 0.00000000000000000000000000000000000000000000000000000000000000002592 227.0
TLS3_k127_921459_2 SWIB/MDM2 domain K03169 - 5.99.1.2 0.00000000000000000000000000000000004043 136.0
TLS3_k127_922430_0 Tetratricopeptide repeat - - - 0.0 1077.0
TLS3_k127_922430_1 MotA/TolQ/ExbB proton channel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 304.0
TLS3_k127_922430_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000008199 187.0
TLS3_k127_922430_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000002662 139.0
TLS3_k127_922430_4 - - - - 0.00000000000000000000000000000002948 131.0
TLS3_k127_922430_5 Biopolymer transport protein ExbD/TolR - - - 0.00000000001398 65.0
TLS3_k127_922665_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 430.0
TLS3_k127_922665_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 366.0
TLS3_k127_922665_2 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.0000000000000000000000000000000000000000000000000000000000001031 216.0
TLS3_k127_953455_0 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 457.0
TLS3_k127_953455_1 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 282.0
TLS3_k127_953455_2 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000004407 193.0
TLS3_k127_959300_0 Alcohol dehydrogenase GroES-like domain K13979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 551.0
TLS3_k127_959300_1 Domain of unknown function (DUF3482) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 478.0
TLS3_k127_959300_2 ATPase family associated with various cellular activities (AAA) - - - 0.000000003503 63.0
TLS3_k127_961009_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 601.0
TLS3_k127_961009_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 445.0
TLS3_k127_961009_2 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000002721 177.0
TLS3_k127_961009_3 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000004254 143.0
TLS3_k127_974915_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 460.0
TLS3_k127_974915_1 Protein of unknown function (DUF1847) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 300.0
TLS3_k127_983857_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 496.0
TLS3_k127_983857_1 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 299.0
TLS3_k127_983857_2 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000000000000000000000817 175.0
TLS3_k127_98680_0 synthetase K01907 - 6.2.1.16 9.523e-265 829.0
TLS3_k127_98680_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 308.0
TLS3_k127_999848_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.57e-205 659.0
TLS3_k127_999848_1 PFAM Tripartite tricarboxylate transporter family receptor K07795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007396 342.0
TLS3_k127_999848_2 Ammonia monooxygenase K07120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 336.0
TLS3_k127_999848_3 Multidrug ABC transporter permease K02004 - - 0.00000000000000000000000000000000000000000000000000001432 192.0
TLS3_k127_999848_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000004191 115.0