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Overview

ID MAG04036
Name TLS3_bin.12
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Burkholderiaceae
Genus JACCZX01
Species
Assembly information
Completeness (%) 91.88
Contamination (%) 1.11
GC content (%) 62.0
N50 (bp) 18,214
Genome size (bp) 3,208,604

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3050

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1006968_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 589.0
TLS3_k127_1006968_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006333 469.0
TLS3_k127_1006968_2 luxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001949 262.0
TLS3_k127_1006968_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005472 260.0
TLS3_k127_1006968_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000004072 252.0
TLS3_k127_1006968_5 ANTAR K22010 - - 0.00000000000000000000000000000000000000000000000001389 186.0
TLS3_k127_1006968_6 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000003486 173.0
TLS3_k127_1006968_7 - - - - 0.00000000000001334 80.0
TLS3_k127_1006968_8 His Kinase A (phosphoacceptor) domain - - - 0.0000009319 63.0
TLS3_k127_1010489_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.248e-233 728.0
TLS3_k127_1010489_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009292 464.0
TLS3_k127_1010489_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000000000000000000008066 220.0
TLS3_k127_1010489_11 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000000000000000001948 222.0
TLS3_k127_1010489_12 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000002535 198.0
TLS3_k127_1010489_13 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000000000000000004259 188.0
TLS3_k127_1010489_14 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000000000001629 171.0
TLS3_k127_1010489_15 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000003291 167.0
TLS3_k127_1010489_16 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000001812 153.0
TLS3_k127_1010489_17 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000000005419 148.0
TLS3_k127_1010489_18 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000000000000000000002633 148.0
TLS3_k127_1010489_19 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000001285 125.0
TLS3_k127_1010489_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 402.0
TLS3_k127_1010489_20 Ribosomal protein L30 K02907 - - 0.000000000000002107 81.0
TLS3_k127_1010489_21 Ribosomal L29 protein K02904 - - 0.000000000000003255 77.0
TLS3_k127_1010489_22 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000402 69.0
TLS3_k127_1010489_23 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000009533 63.0
TLS3_k127_1010489_24 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000005275 54.0
TLS3_k127_1010489_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 316.0
TLS3_k127_1010489_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 305.0
TLS3_k127_1010489_5 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005257 278.0
TLS3_k127_1010489_6 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001221 261.0
TLS3_k127_1010489_7 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000358 243.0
TLS3_k127_1010489_8 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000000492 227.0
TLS3_k127_1010489_9 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000000000007506 227.0
TLS3_k127_1025787_0 ABC transporter K06020 - 3.6.3.25 2.051e-289 895.0
TLS3_k127_1025787_1 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006671 582.0
TLS3_k127_1025787_2 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 307.0
TLS3_k127_1025787_3 GCN5-related N-acetyl-transferase K06975 - - 0.0000000000000000000001592 100.0
TLS3_k127_1025787_4 Major Facilitator Superfamily - - - 0.00000000000000003668 84.0
TLS3_k127_1028435_0 Male sterility protein - - - 1.14e-240 753.0
TLS3_k127_1028435_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 325.0
TLS3_k127_1028435_2 Bacterial transcriptional repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 305.0
TLS3_k127_1028435_3 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000000000001058 257.0
TLS3_k127_1028435_4 Bacterial protein of unknown function (DUF924) - - - 0.0000000000000000000000000000000000000000000000000000000007359 210.0
TLS3_k127_1028435_5 PFAM poly granule associated family protein - - - 0.00000000000000000000000000000002652 132.0
TLS3_k127_1032683_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 3.606e-227 711.0
TLS3_k127_1032683_1 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 315.0
TLS3_k127_1092547_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 6.577e-292 914.0
TLS3_k127_1092547_1 Sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 601.0
TLS3_k127_1092547_10 - - - - 0.0000004761 55.0
TLS3_k127_1092547_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 296.0
TLS3_k127_1092547_3 Glutaredoxin-family domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 299.0
TLS3_k127_1092547_4 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000125 291.0
TLS3_k127_1092547_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002119 265.0
TLS3_k127_1092547_6 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000001252 118.0
TLS3_k127_1092547_7 PFAM zinc finger, DksA TraR C4-type - - - 0.00000000000000000008318 94.0
TLS3_k127_1092547_8 bacterial OsmY and nodulation domain - - - 0.0000000002431 68.0
TLS3_k127_1092547_9 bacterial OsmY and nodulation domain K04065 - - 0.000000002905 64.0
TLS3_k127_1098758_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 314.0
TLS3_k127_1098758_1 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000002564 228.0
TLS3_k127_1098758_2 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.000000000000000000000000000000000000000000000000000000000001734 224.0
TLS3_k127_1101538_0 e1 component (alpha subunit) K00166 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007877 592.0
TLS3_k127_1101538_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 488.0
TLS3_k127_1101538_2 Transketolase, C-terminal domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 376.0
TLS3_k127_1101538_3 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000001106 233.0
TLS3_k127_1101538_4 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000002632 209.0
TLS3_k127_1103953_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 2.087e-305 948.0
TLS3_k127_1103953_1 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 473.0
TLS3_k127_1103953_10 Periplasmic protein thiol disulfide oxidoreductase DsbE K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005768 250.0
TLS3_k127_1103953_11 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000000000000294 228.0
TLS3_k127_1103953_12 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000000000000000001168 221.0
TLS3_k127_1103953_13 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000284 207.0
TLS3_k127_1103953_14 methyltransferase - - - 0.000000000000000000000000000000000000000127 157.0
TLS3_k127_1103953_15 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000008997 134.0
TLS3_k127_1103953_16 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000008679 136.0
TLS3_k127_1103953_17 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - 0.00000005735 55.0
TLS3_k127_1103953_18 - - - - 0.00000006417 56.0
TLS3_k127_1103953_2 GMP synthase C terminal domain K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 456.0
TLS3_k127_1103953_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 372.0
TLS3_k127_1103953_4 Histidine kinase K20975 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 319.0
TLS3_k127_1103953_5 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 291.0
TLS3_k127_1103953_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005603 274.0
TLS3_k127_1103953_7 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001288 277.0
TLS3_k127_1103953_8 PFAM peptidase U61, LD-carboxypeptidase A K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000005135 255.0
TLS3_k127_1103953_9 Bacterial regulatory proteins, luxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005293 248.0
TLS3_k127_1139608_0 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000961 512.0
TLS3_k127_1139608_1 Ferritin-like K20087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 339.0
TLS3_k127_1139608_2 - - - - 0.0000000000000000000213 92.0
TLS3_k127_1150091_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 5.782e-280 867.0
TLS3_k127_1150091_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 4.933e-226 705.0
TLS3_k127_1150091_2 SAF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 623.0
TLS3_k127_1150091_3 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 529.0
TLS3_k127_1150091_4 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 474.0
TLS3_k127_1150091_5 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 409.0
TLS3_k127_1150091_6 Two component transcriptional regulator K02483,K07659 - - 0.00000000000000000000000000000000000000000000000000000000000003282 222.0
TLS3_k127_1150091_7 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07638 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0047484,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0080134,GO:0098552,GO:0098562,GO:0140096,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000003619 168.0
TLS3_k127_1150091_9 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000000000004081 113.0
TLS3_k127_1183325_0 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 429.0
TLS3_k127_1186574_0 Transposase DDE domain K07487 - - 5.796e-200 630.0
TLS3_k127_1186574_1 Protein of unknown function (DUF421) - - - 0.00000000000000000000000000000007288 127.0
TLS3_k127_1186574_2 - - - - 0.00000000000000004371 81.0
TLS3_k127_1188736_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 6.38e-320 1000.0
TLS3_k127_1188736_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 1.03e-300 941.0
TLS3_k127_1188736_10 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 302.0
TLS3_k127_1188736_11 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 286.0
TLS3_k127_1188736_12 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002612 279.0
TLS3_k127_1188736_13 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000002989 260.0
TLS3_k127_1188736_14 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000005582 196.0
TLS3_k127_1188736_15 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000000000000003176 195.0
TLS3_k127_1188736_16 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000002291 175.0
TLS3_k127_1188736_2 Metallopeptidase family M24 K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 467.0
TLS3_k127_1188736_3 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009705 436.0
TLS3_k127_1188736_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007782 417.0
TLS3_k127_1188736_5 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 389.0
TLS3_k127_1188736_6 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 401.0
TLS3_k127_1188736_7 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 379.0
TLS3_k127_1188736_8 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009624 379.0
TLS3_k127_1188736_9 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 310.0
TLS3_k127_1198033_0 Proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 1.115e-216 682.0
TLS3_k127_1198033_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 7.465e-216 682.0
TLS3_k127_1198033_10 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000001573 138.0
TLS3_k127_1198033_2 Glucose / Sorbosone dehydrogenase - - - 4.308e-200 634.0
TLS3_k127_1198033_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 537.0
TLS3_k127_1198033_4 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005169 464.0
TLS3_k127_1198033_5 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 355.0
TLS3_k127_1198033_6 Inhibitor of apoptosis-promoting Bax1 K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006884 340.0
TLS3_k127_1198033_7 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002096 276.0
TLS3_k127_1198033_8 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000104 226.0
TLS3_k127_1198033_9 membrane - - - 0.00000000000000000000000000000000000001257 148.0
TLS3_k127_1198182_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 581.0
TLS3_k127_1198182_1 Histidine kinase K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 524.0
TLS3_k127_1198182_2 Transcriptional regulatory protein, C terminal K02483,K07666,K07774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 348.0
TLS3_k127_1198182_3 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.0000000000000000000000000000006474 122.0
TLS3_k127_1202542_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 9.167e-293 919.0
TLS3_k127_1202542_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 3.584e-204 644.0
TLS3_k127_1202542_10 Fatty acid desaturase K00496 - 1.14.15.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000168 271.0
TLS3_k127_1202542_11 phosphoribosyltransferase K07101 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003889 252.0
TLS3_k127_1202542_12 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000002504 212.0
TLS3_k127_1202542_13 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000004449 207.0
TLS3_k127_1202542_14 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000002916 141.0
TLS3_k127_1202542_15 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.00000000000131 71.0
TLS3_k127_1202542_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 587.0
TLS3_k127_1202542_3 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 546.0
TLS3_k127_1202542_4 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 441.0
TLS3_k127_1202542_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 432.0
TLS3_k127_1202542_6 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 413.0
TLS3_k127_1202542_7 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 339.0
TLS3_k127_1202542_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 314.0
TLS3_k127_1202542_9 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 290.0
TLS3_k127_1222092_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 8.187e-312 964.0
TLS3_k127_1222092_1 Large family of predicted nucleotide-binding domains K07175 - - 3.006e-243 761.0
TLS3_k127_1222092_10 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008871 237.0
TLS3_k127_1222092_11 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000004097 239.0
TLS3_k127_1222092_12 PFAM molybdopterin biosynthesis MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000006532 221.0
TLS3_k127_1222092_13 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000000000000001155 156.0
TLS3_k127_1222092_14 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000001218 159.0
TLS3_k127_1222092_15 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000000000000002402 155.0
TLS3_k127_1222092_16 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000000002426 93.0
TLS3_k127_1222092_17 PFAM cytochrome c, class I - - - 0.0000000001662 70.0
TLS3_k127_1222092_2 Aminotransferase K14261 - - 7.056e-216 675.0
TLS3_k127_1222092_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 605.0
TLS3_k127_1222092_4 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 603.0
TLS3_k127_1222092_5 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 581.0
TLS3_k127_1222092_6 protein conserved in bacteria K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 554.0
TLS3_k127_1222092_7 ATP dependent DNA ligase C terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 508.0
TLS3_k127_1222092_8 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009078 501.0
TLS3_k127_1222092_9 surface antigen (D15) K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 448.0
TLS3_k127_1226870_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.362e-312 962.0
TLS3_k127_1226870_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 8.535e-217 679.0
TLS3_k127_1226870_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 567.0
TLS3_k127_1226870_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008009 379.0
TLS3_k127_1226870_4 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 305.0
TLS3_k127_1226870_5 Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 285.0
TLS3_k127_1226870_6 Protein of unknown function (DUF541) - - - 0.00000000000000000000000002309 118.0
TLS3_k127_1248551_0 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 2.37e-222 698.0
TLS3_k127_1248551_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 7.708e-222 700.0
TLS3_k127_1248551_10 EamA-like transporter family K15268 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009337 248.0
TLS3_k127_1248551_11 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000545 226.0
TLS3_k127_1248551_12 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000007929 192.0
TLS3_k127_1248551_13 Tripartite ATP-independent periplasmic transporter, DctQ - - - 0.00000000000000000000000000000000000000005088 156.0
TLS3_k127_1248551_14 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit K03299 - - 0.0000000000000000000000000002249 116.0
TLS3_k127_1248551_15 Uroporphyrinogen-III synthase K01719,K13543 - 2.1.1.107,4.2.1.75 0.0000000000000000000004125 108.0
TLS3_k127_1248551_2 argininosuccinate lyase K01755 - 4.3.2.1 9.549e-206 650.0
TLS3_k127_1248551_3 Trap dicarboxylate transporter, dctm subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 562.0
TLS3_k127_1248551_4 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 470.0
TLS3_k127_1248551_5 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 469.0
TLS3_k127_1248551_6 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 357.0
TLS3_k127_1248551_7 LytTr DNA-binding domain K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001325 273.0
TLS3_k127_1248551_8 HemY protein N-terminus K02498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004983 256.0
TLS3_k127_1248551_9 Tripartite ATP-independent periplasmic transporter DctQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000236 244.0
TLS3_k127_129051_0 DEAD DEAH box helicase K03724 - - 0.0 1865.0
TLS3_k127_129051_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.517e-281 878.0
TLS3_k127_129051_10 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007312 386.0
TLS3_k127_129051_11 Aldo/keto reductase family K00011 - 1.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 325.0
TLS3_k127_129051_12 dioxygenase of extradiol dioxygenase family K06991 - - 0.000000000000000000000000000000000000000000000000000000000000000000832 230.0
TLS3_k127_129051_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000005153 218.0
TLS3_k127_129051_14 Histidine phosphatase superfamily (branch 1) - - - 0.000000000000000000000000000000000000000000004816 169.0
TLS3_k127_129051_15 Protein of unknown function (DUF3072) - - - 0.000000000000000000000000001262 116.0
TLS3_k127_129051_16 - - - - 0.00000000000002026 78.0
TLS3_k127_129051_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.344e-250 784.0
TLS3_k127_129051_3 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03669 - - 5.376e-247 786.0
TLS3_k127_129051_4 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 2.561e-208 662.0
TLS3_k127_129051_5 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 589.0
TLS3_k127_129051_6 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 587.0
TLS3_k127_129051_7 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 511.0
TLS3_k127_129051_8 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 429.0
TLS3_k127_129051_9 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 413.0
TLS3_k127_1337103_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 3.848e-209 655.0
TLS3_k127_1337103_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 500.0
TLS3_k127_1413152_0 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1594.0
TLS3_k127_1413152_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124 - - 1.672e-268 833.0
TLS3_k127_1413152_11 SMART cyclic nucleotide-binding K10914 - - 0.00000000000000000000000000000000000000000000000000000000001906 213.0
TLS3_k127_1413152_12 Thioredoxin-like [2Fe-2S] ferredoxin K00127 - - 0.0000000000000000000000000000000000000000000000000000000009841 207.0
TLS3_k127_1413152_13 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000002265 173.0
TLS3_k127_1413152_14 - - - - 0.00000000000000000000000000000000000000000001433 173.0
TLS3_k127_1413152_15 Domain of unknown function (DUF4281) - - - 0.0000000000000000000000000000000000001392 146.0
TLS3_k127_1413152_16 GrpB protein - - - 0.000000000000000000000000000000000002221 146.0
TLS3_k127_1413152_17 Branched-chain amino acid transport protein (AzlD) - - - 0.000000000000000000004393 96.0
TLS3_k127_1413152_18 formate dehydrogenase K00126 - 1.17.1.9 0.000000000000000001389 92.0
TLS3_k127_1413152_19 AzlC protein - - - 0.000000000000001269 79.0
TLS3_k127_1413152_2 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.781e-226 704.0
TLS3_k127_1413152_3 AMP-binding enzyme C-terminal domain K18661 - - 1.865e-205 656.0
TLS3_k127_1413152_4 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 394.0
TLS3_k127_1413152_5 Transcriptional regulator of molybdate metabolism, LysR family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 367.0
TLS3_k127_1413152_6 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009996 320.0
TLS3_k127_1413152_7 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379,K18360 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 304.0
TLS3_k127_1413152_8 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005632 273.0
TLS3_k127_1413152_9 glutathione transferase activity K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000002656 249.0
TLS3_k127_1418869_0 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 446.0
TLS3_k127_1418869_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 425.0
TLS3_k127_1418869_2 abc transporter K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004182 270.0
TLS3_k127_1465555_0 CoA-transferase family III K07749 - 2.8.3.16 1.6e-211 663.0
TLS3_k127_1465555_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 540.0
TLS3_k127_1465555_10 - - - - 0.000000000000000000000004775 111.0
TLS3_k127_1465555_11 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.000000000000000004536 98.0
TLS3_k127_1465555_12 nuclease K01174 - 3.1.31.1 0.000000000000002692 77.0
TLS3_k127_1465555_13 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00000000008688 73.0
TLS3_k127_1465555_14 serine threonine protein kinase K12132 - 2.7.11.1 0.00000001929 67.0
TLS3_k127_1465555_2 aldo keto reductase K19265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 501.0
TLS3_k127_1465555_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 494.0
TLS3_k127_1465555_4 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 490.0
TLS3_k127_1465555_5 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005774 448.0
TLS3_k127_1465555_6 epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 439.0
TLS3_k127_1465555_7 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 309.0
TLS3_k127_1465555_8 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000003725 245.0
TLS3_k127_1465555_9 Peptidase family M23 K21472 - - 0.000000000000000000000000000000000000000000000000000000002778 205.0
TLS3_k127_1547083_0 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000909 462.0
TLS3_k127_1547083_1 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 454.0
TLS3_k127_1547083_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 354.0
TLS3_k127_1547083_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000008509 221.0
TLS3_k127_1547083_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000435 149.0
TLS3_k127_1549797_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 353.0
TLS3_k127_1549797_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 309.0
TLS3_k127_1549797_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004335 268.0
TLS3_k127_1549797_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001434 251.0
TLS3_k127_1549797_4 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000000000000000000000000000000009194 151.0
TLS3_k127_1549797_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000149 79.0
TLS3_k127_1549797_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000001744 64.0
TLS3_k127_1557634_0 Alcohol dehydrogenase GroES-like domain - - - 2.008e-197 619.0
TLS3_k127_1557634_1 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000002286 187.0
TLS3_k127_1557634_2 Hemerythrin HHE cation binding domain - - - 0.0000000000000000972 81.0
TLS3_k127_158292_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 3.807e-212 668.0
TLS3_k127_158292_1 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000000002806 211.0
TLS3_k127_158292_2 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000009597 203.0
TLS3_k127_158292_3 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000002031 147.0
TLS3_k127_158292_4 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000000000000000000005926 138.0
TLS3_k127_1619624_0 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000004363 205.0
TLS3_k127_1619624_1 Histidine kinase - - - 0.0000000000000000000000000000000000000002129 164.0
TLS3_k127_1619624_2 Histidine kinase - - - 0.000000000000254 81.0
TLS3_k127_1624036_0 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 3.961e-271 844.0
TLS3_k127_1624036_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K20023 - 4.2.1.156,4.2.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 599.0
TLS3_k127_1624036_2 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 373.0
TLS3_k127_1624036_3 Catalyzes the reversible retro-aldol cleavage of 2-keto- 3-deoxy-L-rhamnonate (KDR) to pyruvate and lactaldehyde K02510,K12660 - 4.1.2.52,4.1.2.53 0.00000000000000000000000000000000009567 136.0
TLS3_k127_1634808_0 Belongs to the peptidase M16 family K07263 - - 1.068e-276 870.0
TLS3_k127_1634808_1 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 372.0
TLS3_k127_1634808_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 361.0
TLS3_k127_1634808_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 330.0
TLS3_k127_1634808_4 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004663 273.0
TLS3_k127_1634808_5 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000005254 240.0
TLS3_k127_1634808_6 Aminomethyltransferase folate-binding domain K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000001895 241.0
TLS3_k127_1634808_7 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000002981 216.0
TLS3_k127_1634808_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000003769 167.0
TLS3_k127_1634808_9 Domain of unknown function (DUF4936) - - - 0.00000001018 59.0
TLS3_k127_1733830_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 7.781e-254 815.0
TLS3_k127_1733830_1 RESPONSE REGULATOR receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 537.0
TLS3_k127_1733830_10 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000013 186.0
TLS3_k127_1733830_11 COGs COG3576 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000042 132.0
TLS3_k127_1733830_12 - - - - 0.0000000000000000000597 93.0
TLS3_k127_1733830_13 - - - - 0.000000000002077 79.0
TLS3_k127_1733830_14 cytochrome C peroxidase - - - 0.000000000009222 65.0
TLS3_k127_1733830_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 488.0
TLS3_k127_1733830_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 449.0
TLS3_k127_1733830_4 Glutamine cyclotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006667 374.0
TLS3_k127_1733830_5 Bacterial protein of unknown function (DUF899) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 371.0
TLS3_k127_1733830_6 ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007437 349.0
TLS3_k127_1733830_7 membrane-bound metal-dependent K07038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 316.0
TLS3_k127_1733830_8 TonB C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 318.0
TLS3_k127_1733830_9 ATPase MipZ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001504 274.0
TLS3_k127_1739392_0 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 552.0
TLS3_k127_1739392_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 428.0
TLS3_k127_1739392_2 proteolysis - - - 0.000003662 56.0
TLS3_k127_1749436_0 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 430.0
TLS3_k127_178050_0 orn lys arg decarboxylase K01584 - 4.1.1.19 0.0 1119.0
TLS3_k127_178050_1 Tripartite tricarboxylate transporter TctA family K07793 - - 2.671e-226 710.0
TLS3_k127_178050_11 Predicted membrane protein (DUF2243) - - - 0.00000000007233 63.0
TLS3_k127_178050_2 Bacterial periplasmic substrate-binding proteins K09969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009943 510.0
TLS3_k127_178050_3 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007711 492.0
TLS3_k127_178050_4 PFAM ABC transporter related K02028,K09972 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 425.0
TLS3_k127_178050_5 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 407.0
TLS3_k127_178050_6 acid transport system permease K09970 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 388.0
TLS3_k127_178050_7 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 297.0
TLS3_k127_178050_8 Domain of unknown function DUF108 K06989 - 1.4.1.21 0.00000000000000000000000000000000000000000000000000000000000311 220.0
TLS3_k127_178050_9 Predicted membrane protein (DUF2243) - - - 0.000000000000000000000000000001669 122.0
TLS3_k127_1785519_0 Phospholipase K01058 GO:0003674,GO:0003824,GO:0004620,GO:0004623,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005623,GO:0008970,GO:0009279,GO:0016020,GO:0016021,GO:0016298,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031975,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044462,GO:0044464,GO:0045203,GO:0046872,GO:0046983,GO:0052689,GO:0071944 3.1.1.32,3.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001399 280.0
TLS3_k127_1785519_1 SMART Prolyl 4-hydroxylase, alpha subunit K00472 - 1.14.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001011 266.0
TLS3_k127_1785519_2 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000206 158.0
TLS3_k127_1785519_3 Cold shock K03704 - - 0.000000000000000000000000000212 114.0
TLS3_k127_1798271_0 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 591.0
TLS3_k127_1798271_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 283.0
TLS3_k127_1798271_2 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000005206 207.0
TLS3_k127_1829067_0 COG0655 Multimeric flavodoxin WrbA - - - 0.000000000000000000000000000000000000000000000000000009023 195.0
TLS3_k127_1829067_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000006081 129.0
TLS3_k127_1829067_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000003548 105.0
TLS3_k127_1829067_3 - - - - 0.0000001267 58.0
TLS3_k127_193573_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1559.0
TLS3_k127_193573_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000001623 184.0
TLS3_k127_1947114_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 624.0
TLS3_k127_1947114_1 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000238 159.0
TLS3_k127_1947114_2 NmrA-like family - - - 0.000000000000000000000008235 107.0
TLS3_k127_1947114_3 DNA repair - GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0036260,GO:0036261,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071164,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.00000000003746 66.0
TLS3_k127_1950349_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1312.0
TLS3_k127_1950349_1 Na H antiporter MnhB subunit-related protein K05559 - - 0.0 1275.0
TLS3_k127_1950349_10 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 424.0
TLS3_k127_1950349_11 PFAM AsmA family protein K07289,K07290 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 437.0
TLS3_k127_1950349_12 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 411.0
TLS3_k127_1950349_13 Methyl-transferase K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 396.0
TLS3_k127_1950349_14 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 387.0
TLS3_k127_1950349_15 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 353.0
TLS3_k127_1950349_16 Biotin-lipoyl like K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 343.0
TLS3_k127_1950349_17 NADPH-dependent FMN reductase K19784 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 310.0
TLS3_k127_1950349_18 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 303.0
TLS3_k127_1950349_19 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 303.0
TLS3_k127_1950349_2 ABC transporter transmembrane region K06147 - - 1.459e-238 751.0
TLS3_k127_1950349_20 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 289.0
TLS3_k127_1950349_21 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000008675 271.0
TLS3_k127_1950349_22 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000003985 260.0
TLS3_k127_1950349_23 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001781 256.0
TLS3_k127_1950349_24 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000001222 224.0
TLS3_k127_1950349_25 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000003229 207.0
TLS3_k127_1950349_26 antiporter K05562 - - 0.00000000000000000000000000000000000000000000008597 173.0
TLS3_k127_1950349_27 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K05560 - - 0.0000000000000000000000000000000000000000000002259 169.0
TLS3_k127_1950349_28 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000008089 142.0
TLS3_k127_1950349_29 - - - - 0.0000000000000000000000000000000000147 139.0
TLS3_k127_1950349_3 FtsX-like permease family K02004 - - 1.036e-211 692.0
TLS3_k127_1950349_30 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000000000000000002691 140.0
TLS3_k127_1950349_31 Multisubunit Na H antiporter, MnhG subunit K05564 - - 0.000000000000000000000000000000009135 135.0
TLS3_k127_1950349_32 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K05563 - - 0.0000000000000000000000000007943 123.0
TLS3_k127_1950349_34 - - - - 0.0001023 50.0
TLS3_k127_1950349_4 PFAM NADH Ubiquinone plastoquinone (complex I) K05561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008831 608.0
TLS3_k127_1950349_5 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 507.0
TLS3_k127_1950349_6 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 482.0
TLS3_k127_1950349_7 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 462.0
TLS3_k127_1950349_8 Lytic transglycosylase K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 465.0
TLS3_k127_1950349_9 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 433.0
TLS3_k127_2021718_0 CoA binding domain - - - 0.0 1127.0
TLS3_k127_2021718_1 Belongs to the TPP enzyme family K01577 - 4.1.1.8 4.348e-306 945.0
TLS3_k127_2021718_10 LysR family K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 458.0
TLS3_k127_2021718_11 probably responsible for the translocation of the substrate across the membrane K02026,K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 452.0
TLS3_k127_2021718_12 Binding-protein-dependent transport system inner membrane component K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 407.0
TLS3_k127_2021718_13 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 394.0
TLS3_k127_2021718_14 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 337.0
TLS3_k127_2021718_15 Glycolate oxidase subunit GlcD K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 290.0
TLS3_k127_2021718_16 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 292.0
TLS3_k127_2021718_17 involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 283.0
TLS3_k127_2021718_18 Biopolymer transport K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001833 261.0
TLS3_k127_2021718_19 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001839 239.0
TLS3_k127_2021718_2 protein conserved in bacteria K07793 - - 9.303e-269 833.0
TLS3_k127_2021718_20 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001923 244.0
TLS3_k127_2021718_21 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000001644 224.0
TLS3_k127_2021718_22 ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000005797 214.0
TLS3_k127_2021718_23 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000000000000001134 182.0
TLS3_k127_2021718_24 Histidine kinase - - - 0.0000000000000000000000000000000000000000000001736 184.0
TLS3_k127_2021718_25 endoribonuclease K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000007067 167.0
TLS3_k127_2021718_26 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000001545 162.0
TLS3_k127_2021718_27 Biopolymer transport protein, ExbD K03559 - - 0.00000000000000000000000000000000000000001053 158.0
TLS3_k127_2021718_28 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000002129 148.0
TLS3_k127_2021718_29 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000000000000000006389 128.0
TLS3_k127_2021718_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.278e-239 764.0
TLS3_k127_2021718_30 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000001915 126.0
TLS3_k127_2021718_31 Cupin 2, conserved barrel domain protein K21700 - - 0.000000000000000000000000006734 115.0
TLS3_k127_2021718_32 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000107 96.0
TLS3_k127_2021718_33 Histidine kinase - - - 0.00000000000001081 85.0
TLS3_k127_2021718_34 - - - - 0.00002368 54.0
TLS3_k127_2021718_4 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 7.569e-239 754.0
TLS3_k127_2021718_5 Glycolate oxidase, iron-sulfur subunit K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 599.0
TLS3_k127_2021718_6 CoA-transferase family III K07749,K14471,K14472 - 2.8.3.16,2.8.3.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 584.0
TLS3_k127_2021718_7 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000763 514.0
TLS3_k127_2021718_8 ATPases associated with a variety of cellular activities K05816,K10111,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 494.0
TLS3_k127_2021718_9 Sodium/hydrogen exchanger family K03316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 496.0
TLS3_k127_2024700_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 2.486e-231 731.0
TLS3_k127_2024700_1 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 488.0
TLS3_k127_2024700_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 362.0
TLS3_k127_2024700_3 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000000001215 204.0
TLS3_k127_2024700_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000002072 176.0
TLS3_k127_2024700_5 Response regulator receiver - - - 0.00000000000000000000000000000000001456 147.0
TLS3_k127_2024700_6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000006531 55.0
TLS3_k127_2028460_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1052.0
TLS3_k127_2028460_1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000019 247.0
TLS3_k127_2034028_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 9.896e-306 948.0
TLS3_k127_2034028_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 521.0
TLS3_k127_2034028_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 441.0
TLS3_k127_2034028_3 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006692 405.0
TLS3_k127_2034028_4 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 349.0
TLS3_k127_2034028_5 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001062 239.0
TLS3_k127_2034028_6 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000016 201.0
TLS3_k127_2034028_7 PFAM NUDIX hydrolase K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000000000000002262 197.0
TLS3_k127_2034028_8 Regulatory protein, FmdB family - - - 0.000000000000000000000003213 109.0
TLS3_k127_2115160_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.424e-284 882.0
TLS3_k127_2115160_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 591.0
TLS3_k127_2115160_10 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 333.0
TLS3_k127_2115160_11 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 322.0
TLS3_k127_2115160_12 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02351 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 310.0
TLS3_k127_2115160_13 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 316.0
TLS3_k127_2115160_14 Phospholipid-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 301.0
TLS3_k127_2115160_15 Riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000001 248.0
TLS3_k127_2115160_16 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003268 243.0
TLS3_k127_2115160_17 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000001174 238.0
TLS3_k127_2115160_18 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000002654 235.0
TLS3_k127_2115160_19 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000008225 218.0
TLS3_k127_2115160_2 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 553.0
TLS3_k127_2115160_20 Required for insertion of 4Fe-4S clusters K15724 - - 0.00000000000000000000000000000000000000000000000000000000000005559 215.0
TLS3_k127_2115160_21 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000002105 209.0
TLS3_k127_2115160_22 Phosphoglycerate mutase K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000001643 211.0
TLS3_k127_2115160_23 regulator of disulfide bond formation K07397 - - 0.00000000000000000000000000000000000000000000000000000003603 201.0
TLS3_k127_2115160_24 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000009152 199.0
TLS3_k127_2115160_25 Gram-negative porin - - - 0.0000000000000000000000000000000000000000000000000005775 205.0
TLS3_k127_2115160_26 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000003583 164.0
TLS3_k127_2115160_27 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000008568 166.0
TLS3_k127_2115160_28 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000942 162.0
TLS3_k127_2115160_29 - - - - 0.00000000000000000000000000000000001302 145.0
TLS3_k127_2115160_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 539.0
TLS3_k127_2115160_30 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000007656 133.0
TLS3_k127_2115160_31 CRISPR system CASCADE complex protein CasE K19126 - - 0.000009761 55.0
TLS3_k127_2115160_32 - - - - 0.00006198 49.0
TLS3_k127_2115160_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 464.0
TLS3_k127_2115160_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 460.0
TLS3_k127_2115160_6 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 368.0
TLS3_k127_2115160_7 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 365.0
TLS3_k127_2115160_8 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 364.0
TLS3_k127_2115160_9 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000929 351.0
TLS3_k127_2143556_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 2.148e-279 869.0
TLS3_k127_2143556_1 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 398.0
TLS3_k127_2143556_2 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 391.0
TLS3_k127_2143556_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 393.0
TLS3_k127_2143556_4 UPF0114 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001003 276.0
TLS3_k127_2143556_5 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009318 271.0
TLS3_k127_2143556_6 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000001198 195.0
TLS3_k127_2143556_7 there appears to be two types of ribosomal proteins L31 in bacterial genomes K02909 - - 0.0000000000000000000000000000000002829 134.0
TLS3_k127_216290_0 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 394.0
TLS3_k127_216290_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000007197 91.0
TLS3_k127_216290_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000135 72.0
TLS3_k127_2166646_0 Extracellular solute-binding protein, family 5 middle family protein 22 - - - 2.388e-286 897.0
TLS3_k127_2166646_1 FAD binding domain K05712 - 1.14.13.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 607.0
TLS3_k127_2166646_10 thioesterase K07107 - - 0.0000000000000000000000000000000000000000001952 164.0
TLS3_k127_2166646_11 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000004358 132.0
TLS3_k127_2166646_12 COG0810 Periplasmic protein TonB, links inner and outer membranes K03646 - - 0.00000000000000000008057 99.0
TLS3_k127_2166646_13 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 0.000000000002945 68.0
TLS3_k127_2166646_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 572.0
TLS3_k127_2166646_3 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 515.0
TLS3_k127_2166646_4 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 520.0
TLS3_k127_2166646_5 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 424.0
TLS3_k127_2166646_6 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 413.0
TLS3_k127_2166646_7 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 291.0
TLS3_k127_2166646_8 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000001965 217.0
TLS3_k127_2166646_9 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000001198 185.0
TLS3_k127_2189971_0 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000003292 217.0
TLS3_k127_2189971_1 Oxidoreductase family, NAD-binding Rossmann fold K10219 - 1.1.1.312 0.00000000007609 63.0
TLS3_k127_2189971_2 Oxidoreductase family, NAD-binding Rossmann fold K10219 - 1.1.1.312 0.0003889 48.0
TLS3_k127_2209471_0 ABC-type dipeptide transport system periplasmic component K02035 - - 5.204e-217 679.0
TLS3_k127_2209471_1 ADP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 415.0
TLS3_k127_2231311_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 9.651e-298 927.0
TLS3_k127_2231311_1 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 3.545e-222 698.0
TLS3_k127_2231311_2 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 525.0
TLS3_k127_2231311_3 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 405.0
TLS3_k127_2231311_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 400.0
TLS3_k127_2231311_5 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000004876 236.0
TLS3_k127_2308932_0 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 2.406e-270 841.0
TLS3_k127_2308932_1 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 1.191e-233 733.0
TLS3_k127_2308932_10 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000003275 192.0
TLS3_k127_2308932_11 RES - - - 0.0000000000000000000000000000000000000000002085 167.0
TLS3_k127_2308932_12 Isochorismatase family - - - 0.0000000000000000000000000000000000000000447 157.0
TLS3_k127_2308932_13 Protein of unknown function (DUF2384) - - - 0.0000000000000000000000000000000000002568 144.0
TLS3_k127_2308932_14 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000002585 144.0
TLS3_k127_2308932_2 3-oxoacid CoA-transferase, A subunit K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 374.0
TLS3_k127_2308932_3 transferase K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 351.0
TLS3_k127_2308932_4 Membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 351.0
TLS3_k127_2308932_5 short-chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 339.0
TLS3_k127_2308932_6 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 331.0
TLS3_k127_2308932_7 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 303.0
TLS3_k127_2308932_8 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002954 277.0
TLS3_k127_2308932_9 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000002616 193.0
TLS3_k127_2320012_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1719.0
TLS3_k127_2320012_1 B12 binding domain K00548 - 2.1.1.13 0.0 1642.0
TLS3_k127_2320012_10 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006838 372.0
TLS3_k127_2320012_11 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 362.0
TLS3_k127_2320012_12 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 336.0
TLS3_k127_2320012_13 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 338.0
TLS3_k127_2320012_14 Hydrolases of the alpha beta superfamily K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 332.0
TLS3_k127_2320012_15 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 319.0
TLS3_k127_2320012_16 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 294.0
TLS3_k127_2320012_17 Regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000904 280.0
TLS3_k127_2320012_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008582 282.0
TLS3_k127_2320012_19 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000005021 244.0
TLS3_k127_2320012_2 dna topoisomerase III K03169 - 5.99.1.2 0.0 1169.0
TLS3_k127_2320012_20 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000001963 213.0
TLS3_k127_2320012_21 Nuclear protein SET K07117 - - 0.00000000000000000000000000000000000000000000000000000000789 203.0
TLS3_k127_2320012_22 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000002709 205.0
TLS3_k127_2320012_23 signal peptide protein - - - 0.00000000000000000000000000000000000000000000000002501 185.0
TLS3_k127_2320012_24 Ceramidase - - - 0.00000000000000000000000000000000000000000007058 170.0
TLS3_k127_2320012_25 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000001468 149.0
TLS3_k127_2320012_26 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.000000000000000000000000000000001216 145.0
TLS3_k127_2320012_27 Protein of unknown function (DUF3567) - - - 0.00000000000000000000218 97.0
TLS3_k127_2320012_28 response regulator - - - 0.0000000000002309 71.0
TLS3_k127_2320012_3 C4-dicarboxylate transport system permease DctM subunit - - - 7.789e-272 855.0
TLS3_k127_2320012_4 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 2.514e-223 716.0
TLS3_k127_2320012_5 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 621.0
TLS3_k127_2320012_6 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 602.0
TLS3_k127_2320012_7 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 604.0
TLS3_k127_2320012_8 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008882 574.0
TLS3_k127_2320012_9 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 541.0
TLS3_k127_2334068_0 thiamine-containing compound biosynthetic process - - - 0.0000000000000000000000000000000000000000000000006766 179.0
TLS3_k127_2378582_0 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 9.806e-251 781.0
TLS3_k127_2378582_1 helicase K03722 - 3.6.4.12 2.832e-199 644.0
TLS3_k127_2378582_10 Membrane - - - 0.00000008266 63.0
TLS3_k127_2378582_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 531.0
TLS3_k127_2378582_3 PFAM AFG1-family ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 507.0
TLS3_k127_2378582_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 337.0
TLS3_k127_2378582_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001012 291.0
TLS3_k127_2378582_6 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001603 236.0
TLS3_k127_2378582_7 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000009909 224.0
TLS3_k127_2378582_8 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000003889 99.0
TLS3_k127_2378582_9 Protein of unknown function (DUF465) - - - 0.0000000000000000002882 89.0
TLS3_k127_2387949_0 TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase K01740 - 2.5.1.49 6.308e-200 630.0
TLS3_k127_2387949_1 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 508.0
TLS3_k127_2387949_2 PFAM 3-hydroxyacyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 372.0
TLS3_k127_2387949_3 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 318.0
TLS3_k127_2387949_4 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001814 293.0
TLS3_k127_2387949_5 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000000137 251.0
TLS3_k127_2387949_6 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001226 242.0
TLS3_k127_2387949_7 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000001298 229.0
TLS3_k127_2387949_8 CoA-binding protein K06929 - - 0.00000000000000000000000000000000000000000000000000000000000001626 218.0
TLS3_k127_2387949_9 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0000000000000128 74.0
TLS3_k127_2426702_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1035.0
TLS3_k127_2426702_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 7.454e-297 932.0
TLS3_k127_2426702_10 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 396.0
TLS3_k127_2426702_11 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 354.0
TLS3_k127_2426702_12 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 284.0
TLS3_k127_2426702_13 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002297 263.0
TLS3_k127_2426702_14 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003056 244.0
TLS3_k127_2426702_15 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000008475 235.0
TLS3_k127_2426702_16 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000001855 203.0
TLS3_k127_2426702_17 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000001051 192.0
TLS3_k127_2426702_18 protein conserved in bacteria K09928 - - 0.0000000000000000000000000000000000000000000000000001316 191.0
TLS3_k127_2426702_19 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000008455 182.0
TLS3_k127_2426702_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 4.098e-238 756.0
TLS3_k127_2426702_20 PFAM regulatory protein, MerR - - - 0.0000000000000000000000000000000000000000000000122 173.0
TLS3_k127_2426702_21 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000016 168.0
TLS3_k127_2426702_22 diguanylate cyclase - - - 0.00000000000000000000000000000000000000007514 173.0
TLS3_k127_2426702_23 protein conserved in bacteria - - - 0.000000000000000000000000002953 123.0
TLS3_k127_2426702_24 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000000027 101.0
TLS3_k127_2426702_3 Circularly permuted ATP-grasp type 2 - - - 1.282e-234 735.0
TLS3_k127_2426702_4 single-stranded-DNA-specific exonuclease RecJ K07462 - - 1.155e-206 660.0
TLS3_k127_2426702_5 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 602.0
TLS3_k127_2426702_6 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 553.0
TLS3_k127_2426702_7 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 524.0
TLS3_k127_2426702_8 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008703 521.0
TLS3_k127_2426702_9 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 437.0
TLS3_k127_2496595_0 Protein of unknown function - - - 5.01e-238 784.0
TLS3_k127_2496595_1 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 9.534e-232 726.0
TLS3_k127_2496595_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 499.0
TLS3_k127_2496595_3 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 351.0
TLS3_k127_2496595_4 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000002622 165.0
TLS3_k127_2496595_5 ChrR Cupin-like domain - - - 0.000000000000000000000000000000109 126.0
TLS3_k127_2589158_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 506.0
TLS3_k127_2589158_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 441.0
TLS3_k127_2589158_2 protein conserved in bacteria K09983 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001741 257.0
TLS3_k127_2589158_3 PFAM metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.000000000000000000000000000000005948 147.0
TLS3_k127_2589158_4 Disulfide bond formation protein DsbB - - - 0.00000000000000000001659 93.0
TLS3_k127_2607067_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 451.0
TLS3_k127_2607067_1 Protein of unknown function (DUF2891) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 362.0
TLS3_k127_2607067_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000842 170.0
TLS3_k127_2607067_3 - - - - 0.00000000000000009576 83.0
TLS3_k127_2607067_5 FOG TPR repeat, SEL1 subfamily K07126,K13582 - - 0.0001123 54.0
TLS3_k127_2610630_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 2.334e-201 637.0
TLS3_k127_2610630_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 512.0
TLS3_k127_2610630_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 367.0
TLS3_k127_2610630_3 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 325.0
TLS3_k127_2610630_4 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000001127 221.0
TLS3_k127_2610630_5 ApaG domain K06195 - - 0.000000000000000000000000000000000000000000000000001284 185.0
TLS3_k127_2610630_7 protease with the C-terminal PDZ domain - - - 0.0000000000000001726 82.0
TLS3_k127_2633615_0 Uncharacterized protein conserved in bacteria (DUF2090) K03338 - 2.7.1.92 1.281e-217 693.0
TLS3_k127_2633615_1 Extracellular ligand-binding receptor K01999 - - 2.294e-213 671.0
TLS3_k127_2633615_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 419.0
TLS3_k127_2633615_3 PFAM 6-phosphogluconate dehydrogenase NAD-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 392.0
TLS3_k127_2633615_4 NAD dependent epimerase/dehydratase family K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002554 284.0
TLS3_k127_2633615_5 KR domain K00034 - 1.1.1.47 0.000000000000000000000000000000000000000001161 161.0
TLS3_k127_2717402_0 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 3.581e-290 913.0
TLS3_k127_2717402_1 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 525.0
TLS3_k127_2717402_10 tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000001248 139.0
TLS3_k127_2717402_11 Belongs to the frataxin family K06202 - - 0.00000000000000000000000000001765 125.0
TLS3_k127_2717402_12 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000008387 109.0
TLS3_k127_2717402_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 522.0
TLS3_k127_2717402_3 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 462.0
TLS3_k127_2717402_4 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001404 253.0
TLS3_k127_2717402_5 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000000000099 221.0
TLS3_k127_2717402_6 PFAM cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000000008966 223.0
TLS3_k127_2717402_7 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000001526 221.0
TLS3_k127_2717402_8 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000000000000000000000000000000000002572 201.0
TLS3_k127_2717402_9 Pilus assembly protein, PilP K02665 - - 0.00000000000000000000000000000000000000000000001662 178.0
TLS3_k127_2721074_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 549.0
TLS3_k127_2721074_1 - - - - 0.0000000000000007195 81.0
TLS3_k127_2721074_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.0002009 46.0
TLS3_k127_2790502_0 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 2.086e-197 623.0
TLS3_k127_2790502_1 Disulphide bond corrector protein DsbC K04084,K08344 - 1.8.1.8 0.00000000000000000000000000000000000000000000003499 177.0
TLS3_k127_2790502_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000007918 145.0
TLS3_k127_2814066_0 Response regulator receiver K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000968 139.0
TLS3_k127_2814066_1 Diguanylate cyclase - - - 0.0000000000000000000000001713 122.0
TLS3_k127_2814931_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.0 1149.0
TLS3_k127_2814931_1 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 2.27e-321 1002.0
TLS3_k127_2814931_10 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 440.0
TLS3_k127_2814931_11 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 430.0
TLS3_k127_2814931_12 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 419.0
TLS3_k127_2814931_13 Belongs to the peptidase S1C family K04691,K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007743 421.0
TLS3_k127_2814931_14 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 407.0
TLS3_k127_2814931_15 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 408.0
TLS3_k127_2814931_16 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 399.0
TLS3_k127_2814931_17 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 398.0
TLS3_k127_2814931_18 Catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5- (5- phosphoribosylamino)methylideneamino imidazole-4-carboxamide K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 394.0
TLS3_k127_2814931_19 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 393.0
TLS3_k127_2814931_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 4.874e-220 689.0
TLS3_k127_2814931_20 Glutaredoxin K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 368.0
TLS3_k127_2814931_21 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 350.0
TLS3_k127_2814931_22 Thioredoxin-like K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 344.0
TLS3_k127_2814931_23 Succinylglutamate desuccinylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 338.0
TLS3_k127_2814931_24 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 323.0
TLS3_k127_2814931_25 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005814 313.0
TLS3_k127_2814931_26 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 308.0
TLS3_k127_2814931_27 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 306.0
TLS3_k127_2814931_28 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 284.0
TLS3_k127_2814931_29 Cytochrome C1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002117 282.0
TLS3_k127_2814931_3 UDP-galactopyranose mutase K01854 - 5.4.99.9 5.566e-205 642.0
TLS3_k127_2814931_30 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002843 277.0
TLS3_k127_2814931_31 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001726 280.0
TLS3_k127_2814931_32 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001361 259.0
TLS3_k127_2814931_33 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000006424 252.0
TLS3_k127_2814931_34 VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000852 237.0
TLS3_k127_2814931_35 toluene tolerance K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000001197 227.0
TLS3_k127_2814931_36 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000009201 198.0
TLS3_k127_2814931_37 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000006098 196.0
TLS3_k127_2814931_38 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000000000000000000006011 179.0
TLS3_k127_2814931_39 Psort location Extracellular, score K07126 - - 0.0000000000000000000000000000000000000000000000007655 185.0
TLS3_k127_2814931_4 ABC transporter, substrate-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 573.0
TLS3_k127_2814931_40 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000006688 171.0
TLS3_k127_2814931_41 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000000198 167.0
TLS3_k127_2814931_42 Stringent starvation protein B K03600 - - 0.0000000000000000000000000000000000000000000574 165.0
TLS3_k127_2814931_43 protein domain associated with - - - 0.0000000000000000000000000000000000000000004467 165.0
TLS3_k127_2814931_44 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.0000000000000000000000000000000000000001185 152.0
TLS3_k127_2814931_45 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000000000000004129 135.0
TLS3_k127_2814931_46 Belongs to the BolA IbaG family - - - 0.000000000000000000000002648 115.0
TLS3_k127_2814931_47 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000004543 100.0
TLS3_k127_2814931_48 NTP binding protein (Contains STAS domain) K04749,K07122 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716 - 0.000000578 54.0
TLS3_k127_2814931_49 - - - - 0.00008055 52.0
TLS3_k127_2814931_5 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 569.0
TLS3_k127_2814931_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 550.0
TLS3_k127_2814931_7 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 524.0
TLS3_k127_2814931_8 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 498.0
TLS3_k127_2814931_9 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 467.0
TLS3_k127_2887254_0 Sodium/hydrogen exchanger family - - - 3.221e-199 626.0
TLS3_k127_2887254_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 397.0
TLS3_k127_2887254_2 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 426.0
TLS3_k127_2887254_3 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000006042 167.0
TLS3_k127_2887254_4 HD domain K13815 - - 0.0000000000000000000000000000004287 141.0
TLS3_k127_2887254_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000002379 114.0
TLS3_k127_2891752_0 Histidine kinase K02487,K06596 - - 0.0 1124.0
TLS3_k127_2891752_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 602.0
TLS3_k127_2891752_2 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001269 258.0
TLS3_k127_2891752_3 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000003078 166.0
TLS3_k127_2891752_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000007883 152.0
TLS3_k127_2910245_0 Acyl transferase domain in polyketide synthase (PKS) enzymes. - - - 8.355e-255 811.0
TLS3_k127_292104_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1249.0
TLS3_k127_292104_1 peptidase M24 K01262 - 3.4.11.9 5.17e-259 815.0
TLS3_k127_292104_10 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000001928 160.0
TLS3_k127_292104_11 Putative heavy-metal-binding - - - 0.0000000000000000000000000000003408 128.0
TLS3_k127_292104_12 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000001301 121.0
TLS3_k127_292104_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 379.0
TLS3_k127_292104_3 Heavy-metal-associated domain K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 389.0
TLS3_k127_292104_4 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 360.0
TLS3_k127_292104_5 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004928 258.0
TLS3_k127_292104_6 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000002517 246.0
TLS3_k127_292104_7 - - - - 0.00000000000000000000000000000000000000000000000003161 184.0
TLS3_k127_292104_8 Acetyltransferase (GNAT) domain K03825 - - 0.000000000000000000000000000000000000000000000000622 180.0
TLS3_k127_292104_9 peptidase M48, Ste24p - - - 0.000000000000000000000000000000000000000000000239 179.0
TLS3_k127_2951477_0 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 318.0
TLS3_k127_2951477_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000328 245.0
TLS3_k127_2951477_2 Pfam Cupin - - - 0.0000000000000000000000000000000000000000000000000000003852 198.0
TLS3_k127_2951477_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000002472 121.0
TLS3_k127_3009520_0 PFAM VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000002033 244.0
TLS3_k127_3009520_1 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000005114 199.0
TLS3_k127_3009520_2 MlaC protein K07323 - - 0.00000000000000000000000000000000000000000000000000029 192.0
TLS3_k127_301787_0 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 301.0
TLS3_k127_301787_1 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007315 278.0
TLS3_k127_301787_2 Putative DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000006074 206.0
TLS3_k127_301787_3 DoxX K15977 - - 0.0000000000000000000000000000000000000000000000000000000006921 206.0
TLS3_k127_3057535_0 PFAM MmgE PrpD family protein - - - 1.584e-226 710.0
TLS3_k127_3057535_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 494.0
TLS3_k127_3057535_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058,K03778 - 1.1.1.28,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 395.0
TLS3_k127_3057535_3 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 310.0
TLS3_k127_3057535_4 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000702 196.0
TLS3_k127_3057535_5 PFAM sulfatase - - - 0.000000000000000000000000000000000000000000000004968 176.0
TLS3_k127_3057535_6 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000008225 148.0
TLS3_k127_3059757_0 FAD linked oxidase domain protein - - - 0.0 1976.0
TLS3_k127_3059757_1 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 7.34e-240 749.0
TLS3_k127_3059757_10 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 480.0
TLS3_k127_3059757_11 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 442.0
TLS3_k127_3059757_12 MMPL family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 393.0
TLS3_k127_3059757_13 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 337.0
TLS3_k127_3059757_14 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 338.0
TLS3_k127_3059757_15 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 304.0
TLS3_k127_3059757_16 VanZ like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001097 291.0
TLS3_k127_3059757_17 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001892 282.0
TLS3_k127_3059757_18 Reversible hydration of carbon dioxide K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003506 274.0
TLS3_k127_3059757_19 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002432 269.0
TLS3_k127_3059757_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 2.665e-234 737.0
TLS3_k127_3059757_20 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000003041 267.0
TLS3_k127_3059757_21 MltA-interacting protein MipA - - - 0.000000000000000000000000000000000000000000000000000000000000000000003048 253.0
TLS3_k127_3059757_22 pteridine-dependent deoxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000007033 244.0
TLS3_k127_3059757_23 Na H antiporter, MnhB K05566 - - 0.00000000000000000000000000000000000000000000000000000000000000005167 224.0
TLS3_k127_3059757_24 Alpha beta K07018 - - 0.00000000000000000000000000000000000000000000000000000000000001238 222.0
TLS3_k127_3059757_25 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000001321 219.0
TLS3_k127_3059757_26 Na H antiporter, MnhB K05566 - - 0.0000000000000000000000000000000000000000000000000000000002545 212.0
TLS3_k127_3059757_27 COG1863 Multisubunit Na H antiporter MnhE subunit K05569 - - 0.00000000000000000000000000000000000000000000000000000008879 200.0
TLS3_k127_3059757_28 HIT domain - - - 0.00000000000000000000000000000000000000000001357 168.0
TLS3_k127_3059757_29 Ferredoxin - - - 0.00000000000000000000000000000000000000005041 153.0
TLS3_k127_3059757_3 formate hydrogenlyase subunit 3 multisubunit Na H antiporter, MnhD subunit K05568,K12137 - - 1.281e-228 720.0
TLS3_k127_3059757_30 COG1006 Multisubunit Na H antiporter, MnhC subunit K05567 - - 0.00000000000000000000000000000000000000009158 156.0
TLS3_k127_3059757_31 LppC putative lipoprotein K07121 - - 0.0000000000000000000000000000000000000001385 167.0
TLS3_k127_3059757_32 monovalent cation:proton antiporter activity K05571 - - 0.0000000000000000000000000000000000000002371 157.0
TLS3_k127_3059757_33 PFAM transport-associated - - - 0.0000000000000000000000000000000000000009756 156.0
TLS3_k127_3059757_34 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000008141 158.0
TLS3_k127_3059757_35 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.000000000000000000000000000000000175 144.0
TLS3_k127_3059757_36 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000106 117.0
TLS3_k127_3059757_37 Belongs to the UPF0250 family K09158 - - 0.000000000000000000000000001104 125.0
TLS3_k127_3059757_38 Multiple resistance and pH regulation protein F K05570 - - 0.000000000000000000000000001143 115.0
TLS3_k127_3059757_39 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000004318 109.0
TLS3_k127_3059757_4 Proton-conducting membrane transporter - - - 2.402e-228 716.0
TLS3_k127_3059757_40 membrane - - - 0.0000000000000000113 91.0
TLS3_k127_3059757_41 - - - - 0.0000000000000004459 80.0
TLS3_k127_3059757_42 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372 - 4.2.1.59 0.000000000006417 70.0
TLS3_k127_3059757_43 - - - - 0.00000000001387 72.0
TLS3_k127_3059757_44 - - - - 0.00000000001424 68.0
TLS3_k127_3059757_45 PFAM Sporulation domain protein - - - 0.000005548 51.0
TLS3_k127_3059757_5 Proton-conducting membrane transporter - - - 1.342e-216 683.0
TLS3_k127_3059757_6 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 530.0
TLS3_k127_3059757_7 TIGRFAM cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 535.0
TLS3_k127_3059757_8 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 479.0
TLS3_k127_3059757_9 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 471.0
TLS3_k127_307545_0 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 487.0
TLS3_k127_307545_1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000001236 164.0
TLS3_k127_307545_2 - - - - 0.000000000000000000000000221 112.0
TLS3_k127_3089488_0 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 7.667e-204 643.0
TLS3_k127_3089488_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000006887 237.0
TLS3_k127_3126911_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.721e-294 910.0
TLS3_k127_3126911_1 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032,K13892 - - 6.141e-292 910.0
TLS3_k127_3126911_10 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 423.0
TLS3_k127_3126911_11 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000905 404.0
TLS3_k127_3126911_12 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 394.0
TLS3_k127_3126911_13 abc transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 362.0
TLS3_k127_3126911_14 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 349.0
TLS3_k127_3126911_15 haloacid dehalogenase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 345.0
TLS3_k127_3126911_16 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000001876 213.0
TLS3_k127_3126911_17 AzlC protein - - - 0.000000000000000000000000000000000000000001424 162.0
TLS3_k127_3126911_18 Cytochrome K08738 - - 0.000000000000000000000000000000001971 132.0
TLS3_k127_3126911_19 - - - - 0.00000000000003768 75.0
TLS3_k127_3126911_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 4.486e-227 715.0
TLS3_k127_3126911_20 Transglutaminase/protease-like homologues - - - 0.000000003767 59.0
TLS3_k127_3126911_3 PFAM Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 526.0
TLS3_k127_3126911_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 474.0
TLS3_k127_3126911_5 D-amino acid K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 471.0
TLS3_k127_3126911_6 amino acid K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 467.0
TLS3_k127_3126911_7 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 462.0
TLS3_k127_3126911_8 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 452.0
TLS3_k127_3126911_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 435.0
TLS3_k127_313099_0 Phosphoglucomutase K15778 - 5.4.2.2,5.4.2.8 5.214e-207 653.0
TLS3_k127_313099_1 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000005998 178.0
TLS3_k127_313099_2 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000003294 98.0
TLS3_k127_3180255_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.568e-288 897.0
TLS3_k127_3180255_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008887 587.0
TLS3_k127_3180255_10 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000091 303.0
TLS3_k127_3180255_11 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000000000000000000000005547 232.0
TLS3_k127_3180255_12 very-long-chain-acyl-CoA dehydrogenase activity K17880,K18817 - 2.7.1.119,2.7.1.163 0.000000000000000000000000000000000000000000000000000000001303 215.0
TLS3_k127_3180255_13 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.0000000000000000000000000000000000000000000004046 179.0
TLS3_k127_3180255_14 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000006975 170.0
TLS3_k127_3180255_15 - - - - 0.0000000000000000000000000000000000000005839 160.0
TLS3_k127_3180255_16 TraB family K09973 - - 0.00000000000000000000000000000000000002109 156.0
TLS3_k127_3180255_17 Transglycosylase associated protein - - - 0.00000000000000000000000000000000000008811 143.0
TLS3_k127_3180255_18 - - - - 0.0000000000000000000000000000000000002723 146.0
TLS3_k127_3180255_19 Histidine kinase K02030 - - 0.000000000000000000000000000002864 127.0
TLS3_k127_3180255_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 535.0
TLS3_k127_3180255_20 Protein of unknown function (DUF421) - - - 0.000000000001807 73.0
TLS3_k127_3180255_21 Belongs to the UPF0337 (CsbD) family - - - 0.0000002563 53.0
TLS3_k127_3180255_22 helix_turn_helix, Lux Regulon - - - 0.000008844 51.0
TLS3_k127_3180255_3 Domain of unknown function (DUF3482) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 492.0
TLS3_k127_3180255_4 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006718 415.0
TLS3_k127_3180255_5 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 428.0
TLS3_k127_3180255_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 389.0
TLS3_k127_3180255_7 NAD(P)H-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 354.0
TLS3_k127_3180255_8 phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 323.0
TLS3_k127_3180255_9 Protein of unknown function (DUF2868) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 319.0
TLS3_k127_3237686_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 352.0
TLS3_k127_3272601_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 489.0
TLS3_k127_3272601_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 445.0
TLS3_k127_3272601_2 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008881 392.0
TLS3_k127_3272601_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 290.0
TLS3_k127_3272601_4 Domain of unknown function (DUF1772) - - - 0.0000000000000000000000000000000000000002203 154.0
TLS3_k127_3370305_0 Mo-co oxidoreductase dimerisation domain K05301 - 1.8.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 562.0
TLS3_k127_3370305_1 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 488.0
TLS3_k127_3370305_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000125 93.0
TLS3_k127_3388809_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 1.765e-220 686.0
TLS3_k127_3388809_1 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 520.0
TLS3_k127_3388809_2 UreE urease accessory protein, C-terminal domain K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 501.0
TLS3_k127_3388809_3 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 420.0
TLS3_k127_3388809_4 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 394.0
TLS3_k127_3388809_5 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 358.0
TLS3_k127_3388809_6 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 289.0
TLS3_k127_3388809_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000008589 228.0
TLS3_k127_3388809_8 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000002161 161.0
TLS3_k127_3388809_9 Transglycosylase associated protein - - - 0.0000000000000000000000000000000000004406 142.0
TLS3_k127_3437620_0 4Fe-4S dicluster domain - - - 0.0 1406.0
TLS3_k127_3437620_1 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 1.623e-198 631.0
TLS3_k127_3437620_2 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 511.0
TLS3_k127_3437620_3 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 481.0
TLS3_k127_3437620_4 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001124 256.0
TLS3_k127_3437620_5 COG3090 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.00000000000000000000000000000000000000004481 156.0
TLS3_k127_3437620_6 NnrU protein - - - 0.0000000000000000002629 88.0
TLS3_k127_3454301_0 Ferredoxin--NADP reductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 568.0
TLS3_k127_3454301_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 576.0
TLS3_k127_3454301_10 Protein of unknown function (DUF2946) - - - 0.0000000000000000000000000000000000000000003805 164.0
TLS3_k127_3454301_11 SnoaL-like domain - - - 0.0000000000000000000000000001133 121.0
TLS3_k127_3454301_12 Zinc-finger domain - - - 0.000000000000000000002201 94.0
TLS3_k127_3454301_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 484.0
TLS3_k127_3454301_3 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 460.0
TLS3_k127_3454301_4 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 363.0
TLS3_k127_3454301_5 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 365.0
TLS3_k127_3454301_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 315.0
TLS3_k127_3454301_7 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003026 284.0
TLS3_k127_3454301_8 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000001157 235.0
TLS3_k127_3454301_9 branched-chain amino acid permease (azaleucine resistance) - - - 0.0000000000000000000000000000000000000000000000000000001785 204.0
TLS3_k127_3455497_0 ATPase MipZ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004423 247.0
TLS3_k127_3455497_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000001582 93.0
TLS3_k127_3455497_2 FAD dependent oxidoreductase - - - 0.00000000000001356 75.0
TLS3_k127_3462973_0 Uncharacterised protein family (UPF0261) - - - 7.643e-312 972.0
TLS3_k127_3462973_1 Amidohydrolase family - - - 8.7e-201 633.0
TLS3_k127_3462973_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005571 599.0
TLS3_k127_3462973_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 502.0
TLS3_k127_3462973_4 Phosphoenolpyruvate hydrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 460.0
TLS3_k127_3462973_5 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 419.0
TLS3_k127_3462973_6 Flotillin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 386.0
TLS3_k127_3462973_7 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 376.0
TLS3_k127_3462973_8 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 374.0
TLS3_k127_3482874_0 ABC transporter K02471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 350.0
TLS3_k127_3482874_1 Bacterial SH3 domain homologues - - - 0.000000000000000000000000000000000005769 146.0
TLS3_k127_3512837_0 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0 1074.0
TLS3_k127_3512837_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 2.164e-298 928.0
TLS3_k127_3512837_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000002726 173.0
TLS3_k127_3512837_11 Protein of unknown function (DUF4019) - - - 0.00000000000000000000000006002 113.0
TLS3_k127_3512837_12 sister chromatid segregation - - - 0.000000000000000000000008642 109.0
TLS3_k127_3512837_13 Domain of unknown function (DUF1330) - - - 0.00000000000000003609 85.0
TLS3_k127_3512837_15 - - - - 0.0000003984 57.0
TLS3_k127_3512837_2 Sulfate transporter K03321 - - 9.419e-195 629.0
TLS3_k127_3512837_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 589.0
TLS3_k127_3512837_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 527.0
TLS3_k127_3512837_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 428.0
TLS3_k127_3512837_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 411.0
TLS3_k127_3512837_7 Glutathionylspermidine synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 329.0
TLS3_k127_3512837_8 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 325.0
TLS3_k127_3512837_9 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000154 249.0
TLS3_k127_3542680_0 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.0 1094.0
TLS3_k127_3542680_1 PUA-like domain K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000002613 232.0
TLS3_k127_3542680_2 - - - - 0.0000000000000000000000000000000000000000000000000006942 190.0
TLS3_k127_3542680_3 helix_turn_helix, mercury resistance K08365 - - 0.000000000000000000000000000000000000183 146.0
TLS3_k127_3595777_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 342.0
TLS3_k127_3595777_1 PFAM Glycosyl transferase, group 1 K13057 - 2.4.1.245 0.00000000000000000000000321 106.0
TLS3_k127_3617015_0 AMP-binding enzyme K04110 - 6.2.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 525.0
TLS3_k127_3617015_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 362.0
TLS3_k127_3617015_2 enoyl-coa hydratase carnithine racemase K15513 - 4.1.2.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 313.0
TLS3_k127_3634950_0 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 3.218e-276 861.0
TLS3_k127_3634950_1 D-galactarate dehydratase / Altronate hydrolase, C terminus K16846,K16850 - 4.2.1.7,4.4.1.24 4.782e-214 672.0
TLS3_k127_3634950_10 Fumarate K01678,K03780 - 4.2.1.2,4.2.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 305.0
TLS3_k127_3634950_11 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 310.0
TLS3_k127_3634950_12 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000006632 250.0
TLS3_k127_3634950_13 Cytochrome c K17223 - - 0.00000000000000000000000000000000000000000000000000000000000000137 225.0
TLS3_k127_3634950_14 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000000000000000000000000007256 190.0
TLS3_k127_3634950_15 - - - - 0.0000000000000000000000000000000000000000000006312 174.0
TLS3_k127_3634950_16 oxidation protein K17227 - - 0.00000000000000000000000000000000000000000005135 163.0
TLS3_k127_3634950_17 altronate dehydratase K16845 - 4.4.1.24 0.000000000000000000000000000000000000000003877 157.0
TLS3_k127_3634950_18 Thioredoxin-like - - - 0.00000000000000000000000000000000000000001383 158.0
TLS3_k127_3634950_19 Transcriptional regulator - - - 0.000000000000000000000000000000000002697 140.0
TLS3_k127_3634950_2 Mo-co oxidoreductase dimerisation domain K17225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 605.0
TLS3_k127_3634950_20 succinate dehydrogenase K00247 - - 0.0000000000000000000000000000000004052 134.0
TLS3_k127_3634950_21 Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - 0.0000000000000000000000000000007642 124.0
TLS3_k127_3634950_22 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000005362 110.0
TLS3_k127_3634950_3 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 588.0
TLS3_k127_3634950_4 Fe-S type, tartrate fumarate subfamily, alpha subunit K03779 - 4.2.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 446.0
TLS3_k127_3634950_5 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 429.0
TLS3_k127_3634950_6 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 382.0
TLS3_k127_3634950_7 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00245 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 370.0
TLS3_k127_3634950_8 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 361.0
TLS3_k127_3634950_9 cytochrome K08738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 336.0
TLS3_k127_3658058_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.688e-240 755.0
TLS3_k127_3658058_1 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 512.0
TLS3_k127_3658058_10 regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed - - - 0.000000000000002779 85.0
TLS3_k127_3658058_11 - - - - 0.00000000000001422 84.0
TLS3_k127_3658058_12 Flagellar protein FliT K02423 - - 0.000000001183 64.0
TLS3_k127_3658058_13 signal transduction histidine kinase - - - 0.000000001429 59.0
TLS3_k127_3658058_15 Aldo/keto reductase family - - - 0.0001026 48.0
TLS3_k127_3658058_2 Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 290.0
TLS3_k127_3658058_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 297.0
TLS3_k127_3658058_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008874 304.0
TLS3_k127_3658058_5 Protein of unknown function (DUF3025) - - - 0.00000000000000000000000000000000000000000000000000000000000000009387 231.0
TLS3_k127_3658058_6 ANTAR K22010 - - 0.00000000000000000000000000000000000000000000002167 177.0
TLS3_k127_3658058_7 Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02403 - - 0.00000000000000000000000000000001751 130.0
TLS3_k127_3658058_8 Flagellar protein YcgR - - - 0.000000000000000001688 95.0
TLS3_k127_3658058_9 - - - - 0.00000000000000007292 83.0
TLS3_k127_3669421_0 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 312.0
TLS3_k127_3669421_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000001199 225.0
TLS3_k127_3669421_2 Cytochrome c K08738 - - 0.0000000000000000000000005302 106.0
TLS3_k127_3702725_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 428.0
TLS3_k127_3702725_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 419.0
TLS3_k127_3702725_2 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 311.0
TLS3_k127_3702725_3 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000001152 223.0
TLS3_k127_3702725_4 Domain of unknown function (DUF4395) - - - 0.000000000000000000000000000000000000000000000000000000004264 201.0
TLS3_k127_3702725_5 Universal stress protein family - - - 0.0000000000000000000000004099 107.0
TLS3_k127_3702725_6 LTXXQ motif family protein - - - 0.000000000001884 74.0
TLS3_k127_3703228_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 3.43e-242 757.0
TLS3_k127_3703228_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 312.0
TLS3_k127_3703228_2 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006869 243.0
TLS3_k127_3703228_3 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001735 237.0
TLS3_k127_3703228_4 Protein of unknown function (DUF1698) - - - 0.000000000000000000000000000000000000000000000000000000000000002498 228.0
TLS3_k127_3703228_5 - - - - 0.0000000000000000000000000000000000001411 147.0
TLS3_k127_3703228_6 Protein conserved in bacteria - - - 0.000000000000000000000000001826 113.0
TLS3_k127_375810_0 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 489.0
TLS3_k127_375810_1 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002049 246.0
TLS3_k127_375810_2 low molecular weight K03741,K03892 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000003875 214.0
TLS3_k127_375810_3 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000000000000002273 207.0
TLS3_k127_375810_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000003204 192.0
TLS3_k127_375810_5 Regulatory protein ArsR K03892 - - 0.0000000000000000000000000000000001971 135.0
TLS3_k127_3763962_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005352 299.0
TLS3_k127_3763962_1 metal-dependent phosphohydrolase HD - - - 0.00000000000000000000000000001832 135.0
TLS3_k127_3763962_2 helicase activity K05592 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003727,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010501,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019439,GO:0022607,GO:0022613,GO:0022618,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0032268,GO:0032270,GO:0032574,GO:0032575,GO:0033554,GO:0033592,GO:0034057,GO:0034248,GO:0034250,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0034655,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043170,GO:0043487,GO:0043488,GO:0043489,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045934,GO:0046483,GO:0046700,GO:0048255,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070035,GO:0070417,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097617,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902369,GO:1902373,GO:1903311,GO:1903312,GO:2000112 3.6.4.13 0.000000000000000004345 85.0
TLS3_k127_3763962_3 - - - - 0.00000000002309 72.0
TLS3_k127_3772196_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 2.503e-224 709.0
TLS3_k127_3772196_1 Protein of unknown function (DUF3618) - - - 0.0000000000000000000000000000008112 131.0
TLS3_k127_3772196_2 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000000000000000000001745 114.0
TLS3_k127_3772196_3 - - - - 0.00000000005158 71.0
TLS3_k127_3788438_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 2.74e-247 773.0
TLS3_k127_3788438_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 505.0
TLS3_k127_3788438_2 TIGRFAM chorismate mutase domain of proteobacterial P-protein, clade 2 K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 445.0
TLS3_k127_3788438_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00210,K00800 - 1.3.1.12,2.5.1.19 0.0000000000000000000000000000000000000000000000002291 187.0
TLS3_k127_3834934_0 Alpha-2-Macroglobulin K06894 - - 0.0 2127.0
TLS3_k127_3834934_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0 1130.0
TLS3_k127_3834934_2 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 3.836e-228 713.0
TLS3_k127_3834934_3 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 9.867e-200 630.0
TLS3_k127_3834934_4 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 512.0
TLS3_k127_3834934_5 Belongs to the LDH2 MDH2 oxidoreductase family K16844 - 1.1.1.338 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 422.0
TLS3_k127_3834934_6 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 293.0
TLS3_k127_3834934_7 penicillin-binding protein K05367 - 2.4.1.129 0.000000000000000000000000000000000001232 147.0
TLS3_k127_3849078_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 - 1.7.5.1 0.0 1397.0
TLS3_k127_3849078_1 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1390.0
TLS3_k127_3849078_10 Bacterial regulatory proteins, crp family K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 309.0
TLS3_k127_3849078_11 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 289.0
TLS3_k127_3849078_12 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002166 259.0
TLS3_k127_3849078_13 undecaprenyl K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000002355 256.0
TLS3_k127_3849078_14 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000007342 227.0
TLS3_k127_3849078_15 Glycosyltransferase family 25 (LPS biosynthesis protein) K07270 - - 0.0000000000000000000000000000000000000000000002768 192.0
TLS3_k127_3849078_16 O-Antigen ligase - - - 0.0000000000000000000000000000000000000000004101 182.0
TLS3_k127_3849078_17 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000002653 148.0
TLS3_k127_3849078_18 universal stress protein - - - 0.00000000000000000000006199 104.0
TLS3_k127_3849078_19 monooxygenase activity - - - 0.0000000000006743 69.0
TLS3_k127_3849078_2 DNA polymerase K02337 - 2.7.7.7 0.0 1248.0
TLS3_k127_3849078_22 Alcohol dehydrogenase GroES-like domain - - - 0.00002466 51.0
TLS3_k127_3849078_3 Succinyl-CoA ligase like flavodoxin domain K09181 - - 0.0 1018.0
TLS3_k127_3849078_4 nitrite transporter K02575 - - 1.495e-308 950.0
TLS3_k127_3849078_5 Major Facilitator Superfamily K02575 - - 3.831e-214 672.0
TLS3_k127_3849078_6 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 561.0
TLS3_k127_3849078_7 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 529.0
TLS3_k127_3849078_8 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 415.0
TLS3_k127_3849078_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 317.0
TLS3_k127_3890201_0 TIGRFAM TRAP transporter, DctM subunit - - - 1.773e-195 617.0
TLS3_k127_3890201_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 538.0
TLS3_k127_3890201_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 427.0
TLS3_k127_3890201_3 helix_turn _helix lactose operon repressor K02529,K06145 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 313.0
TLS3_k127_3890201_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001649 247.0
TLS3_k127_3893308_0 Iron-containing alcohol dehydrogenase K00043,K13954 - 1.1.1.1,1.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008206 607.0
TLS3_k127_3893308_1 FCD K19776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 380.0
TLS3_k127_3893308_2 Binding-protein-dependent transport system inner membrane component K02050,K15552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005906 269.0
TLS3_k127_3893308_3 viral genome integration into host DNA - - - 0.00000000000000001249 85.0
TLS3_k127_3896703_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 6.939e-200 640.0
TLS3_k127_3896703_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 419.0
TLS3_k127_3896703_2 Amidase K21801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 404.0
TLS3_k127_3896703_3 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 301.0
TLS3_k127_3896703_4 Cobalamin synthesis protein cobW C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000005637 224.0
TLS3_k127_3896703_5 Phosphate-starvation-inducible E - - - 0.000000000000000000000000000000000000000000000000000006336 194.0
TLS3_k127_3896703_6 - - - - 0.0000004618 53.0
TLS3_k127_3905952_0 peroxidase K07223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 314.0
TLS3_k127_3905952_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 306.0
TLS3_k127_3905952_2 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000004164 243.0
TLS3_k127_3905952_3 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000001603 222.0
TLS3_k127_3905952_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000026 126.0
TLS3_k127_3905952_5 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000007519 90.0
TLS3_k127_3915822_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 5.259e-261 823.0
TLS3_k127_3915822_1 Participates in both transcription termination and antitermination K02600 - - 6.115e-218 687.0
TLS3_k127_3915822_10 - - - - 0.000004404 50.0
TLS3_k127_3915822_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 362.0
TLS3_k127_3915822_3 of the double-stranded beta helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001292 266.0
TLS3_k127_3915822_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009762 265.0
TLS3_k127_3915822_5 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000001961 216.0
TLS3_k127_3915822_6 protein conserved in bacteria K09984 - - 0.00000000000000000000000000000000000006121 143.0
TLS3_k127_3915822_7 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000001439 145.0
TLS3_k127_3915822_8 Protein of unknown function (DUF1648) - - - 0.000000000000000000001336 100.0
TLS3_k127_3915822_9 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000001857 86.0
TLS3_k127_3957239_0 DNA ligase K01971 - 6.5.1.1 0.0 1080.0
TLS3_k127_3957239_1 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 1.766e-198 625.0
TLS3_k127_3957239_10 PFAM Acetyltransferase (GNAT) family K00663,K19301 - 2.3.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000222 242.0
TLS3_k127_3957239_11 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000004693 246.0
TLS3_k127_3957239_12 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000003335 228.0
TLS3_k127_3957239_13 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000003915 221.0
TLS3_k127_3957239_14 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000117 153.0
TLS3_k127_3957239_15 Protein of unknown function (DUF4239) - - - 0.0000000000000000000000000000003408 132.0
TLS3_k127_3957239_16 - - - - 0.000000000000000001726 86.0
TLS3_k127_3957239_17 Predicted membrane protein (DUF2061) - - - 0.00000000000000007389 84.0
TLS3_k127_3957239_19 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000008758 48.0
TLS3_k127_3957239_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.851e-195 619.0
TLS3_k127_3957239_20 Domain of unknown function (DUF1731) K07071 - - 0.0002481 49.0
TLS3_k127_3957239_21 - - - - 0.0003254 48.0
TLS3_k127_3957239_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 545.0
TLS3_k127_3957239_4 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 546.0
TLS3_k127_3957239_5 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 439.0
TLS3_k127_3957239_6 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 386.0
TLS3_k127_3957239_7 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 353.0
TLS3_k127_3957239_8 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 299.0
TLS3_k127_3957239_9 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000005599 248.0
TLS3_k127_396195_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 4.693e-260 810.0
TLS3_k127_396195_1 N-terminal half of MaoC dehydratase - - - 1.276e-224 698.0
TLS3_k127_396195_10 PFAM metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000003785 212.0
TLS3_k127_396195_11 Thioesterase superfamily - - - 0.000000000000000000000000000000000000583 153.0
TLS3_k127_396195_12 - - - - 0.0000001514 56.0
TLS3_k127_396195_13 - - - - 0.0000007448 53.0
TLS3_k127_396195_2 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 432.0
TLS3_k127_396195_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 415.0
TLS3_k127_396195_4 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 385.0
TLS3_k127_396195_5 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009895 371.0
TLS3_k127_396195_6 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 291.0
TLS3_k127_396195_7 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001302 265.0
TLS3_k127_396195_8 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009414 248.0
TLS3_k127_396195_9 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000584 244.0
TLS3_k127_402125_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 536.0
TLS3_k127_402125_1 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 336.0
TLS3_k127_402125_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004615 271.0
TLS3_k127_402125_3 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000000000000000000000000000000000000000000000287 206.0
TLS3_k127_402125_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000002182 206.0
TLS3_k127_402125_5 TonB dependent biopolymer transporter integral cytoplasmic membrane subunit, working with ExbB K03559 - - 0.0000000000000000000000000000000000000000000000005045 181.0
TLS3_k127_402125_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000001446 183.0
TLS3_k127_402125_7 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000000000000009853 161.0
TLS3_k127_4079763_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 - 1.7.5.1 0.0 1116.0
TLS3_k127_4079763_1 Nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 5.414e-317 974.0
TLS3_k127_4079763_10 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 327.0
TLS3_k127_4079763_11 TIGRFAM nitrate reductase molybdenum cofactor assembly chaperone K00373 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001699 276.0
TLS3_k127_4079763_12 Exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000009 164.0
TLS3_k127_4079763_13 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000268 159.0
TLS3_k127_4079763_14 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000002942 135.0
TLS3_k127_4079763_15 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000001864 132.0
TLS3_k127_4079763_16 Domain of unknown function (DUF305) - - - 0.00000000000000000000007207 102.0
TLS3_k127_4079763_17 FixH family K09926 - - 0.00000000000000001838 85.0
TLS3_k127_4079763_18 - - - - 0.000000000000003141 78.0
TLS3_k127_4079763_19 Cbb3-type cytochrome oxidase K00407 - - 0.0000000000006263 73.0
TLS3_k127_4079763_2 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 8.512e-269 833.0
TLS3_k127_4079763_20 cytochrome oxidase maturation protein cbb3-type - - - 0.00000006963 55.0
TLS3_k127_4079763_3 cytochrome C oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 595.0
TLS3_k127_4079763_4 cation transport ATPase K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 515.0
TLS3_k127_4079763_5 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007312 504.0
TLS3_k127_4079763_6 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 382.0
TLS3_k127_4079763_7 nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 370.0
TLS3_k127_4079763_8 Reversible hydration of carbon dioxide K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 342.0
TLS3_k127_4079763_9 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 338.0
TLS3_k127_408837_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 567.0
TLS3_k127_408837_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 465.0
TLS3_k127_408837_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 399.0
TLS3_k127_408837_3 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 364.0
TLS3_k127_408837_4 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000124 177.0
TLS3_k127_408840_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 385.0
TLS3_k127_408840_1 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 346.0
TLS3_k127_408840_2 ATPases associated with a variety of cellular activities K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 313.0
TLS3_k127_408840_3 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000001964 82.0
TLS3_k127_4108759_0 Atp-dependent helicase K03578 - 3.6.4.13 0.0 1410.0
TLS3_k127_4108759_1 Tartrate dehydrogenase K07246 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 587.0
TLS3_k127_4108759_10 Phasin protein - - - 0.000000000000000000000000000000000000000008661 160.0
TLS3_k127_4108759_11 - - - - 0.0000000000000000000000357 107.0
TLS3_k127_4108759_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 433.0
TLS3_k127_4108759_3 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 418.0
TLS3_k127_4108759_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 409.0
TLS3_k127_4108759_5 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 347.0
TLS3_k127_4108759_6 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 314.0
TLS3_k127_4108759_7 Belongs to the peptidase S11 family K07262 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002396 274.0
TLS3_k127_4108759_8 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009097 268.0
TLS3_k127_4108759_9 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000000000000000000000000000000000000000004438 193.0
TLS3_k127_4110620_0 ABC-type Fe3 transport system, permease component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 527.0
TLS3_k127_4110620_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 513.0
TLS3_k127_4110620_2 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 514.0
TLS3_k127_4110620_3 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009417 436.0
TLS3_k127_4110620_4 fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 318.0
TLS3_k127_4110620_5 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 303.0
TLS3_k127_4110620_6 Putative FMN-binding domain K07734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001157 265.0
TLS3_k127_4110620_7 lytic murein transglycosylase K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007272 267.0
TLS3_k127_4110620_8 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000002876 206.0
TLS3_k127_4110620_9 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000003982 163.0
TLS3_k127_4114907_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0 2328.0
TLS3_k127_4114907_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1312.0
TLS3_k127_4114907_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 584.0
TLS3_k127_4114907_3 Predicted permease YjgP/YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 351.0
TLS3_k127_4114907_4 Predicted permease YjgP/YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 355.0
TLS3_k127_4114907_5 HxlR family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001475 242.0
TLS3_k127_4114907_6 DNA polymerase III K02339 - 2.7.7.7 0.0000000000000000000000000000012 125.0
TLS3_k127_4127440_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 501.0
TLS3_k127_415398_0 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 2.296e-251 784.0
TLS3_k127_415398_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 531.0
TLS3_k127_415398_2 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 366.0
TLS3_k127_415398_3 Catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive K01577,K01652,K03852 - 2.2.1.6,2.3.3.15,4.1.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 352.0
TLS3_k127_415398_4 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000008842 104.0
TLS3_k127_418980_0 Patatin-like phospholipase - - - 1.135e-216 690.0
TLS3_k127_418980_1 PFAM FAD linked oxidase domain protein K00102,K03777 - 1.1.2.4,1.1.5.12 7.687e-213 678.0
TLS3_k127_418980_2 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 372.0
TLS3_k127_418980_3 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008455 360.0
TLS3_k127_418980_4 Adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001553 269.0
TLS3_k127_418980_5 - - - - 0.0000000000000106 75.0
TLS3_k127_418980_6 Cyclic nucleotide-monophosphate binding domain - - - 0.0002586 47.0
TLS3_k127_4201488_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1052.0
TLS3_k127_4201488_1 carbamoyl transferase, NodU family K00612 - - 5.323e-296 917.0
TLS3_k127_4201488_10 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000004548 234.0
TLS3_k127_4201488_11 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000003124 206.0
TLS3_k127_4201488_12 nodulation - - - 0.000000000000000000000004823 107.0
TLS3_k127_4201488_13 Cyclic phosphodiesterase-like protein - - - 0.00000000000000000003524 96.0
TLS3_k127_4201488_14 - - - - 0.000000000000000004474 85.0
TLS3_k127_4201488_2 C-methyltransferase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 582.0
TLS3_k127_4201488_3 Aminotransferase K00832 - 2.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 519.0
TLS3_k127_4201488_4 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 460.0
TLS3_k127_4201488_5 Glucose-1-phosphate cytidylyltransferase K00978,K15669 - 2.7.7.33,2.7.7.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 396.0
TLS3_k127_4201488_6 Nucleotidyl transferase K00978 - 2.7.7.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 392.0
TLS3_k127_4201488_7 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 344.0
TLS3_k127_4201488_8 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 328.0
TLS3_k127_4201488_9 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 304.0
TLS3_k127_4214032_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 5.351e-312 973.0
TLS3_k127_4214032_1 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 4.112e-303 942.0
TLS3_k127_4214032_10 Extracellular liganD-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 589.0
TLS3_k127_4214032_11 VWA containing CoxE family protein K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 567.0
TLS3_k127_4214032_12 UDP binding domain K00066 - 1.1.1.132 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008891 542.0
TLS3_k127_4214032_13 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 532.0
TLS3_k127_4214032_14 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 501.0
TLS3_k127_4214032_15 ATPase (AAA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 481.0
TLS3_k127_4214032_16 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 465.0
TLS3_k127_4214032_17 TIGRFAM polysaccharide chain length determinant protein, PEP-CTERM locus subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 473.0
TLS3_k127_4214032_18 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 452.0
TLS3_k127_4214032_19 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 450.0
TLS3_k127_4214032_2 Molecular chaperone. Has ATPase activity K04079 - - 2.215e-281 877.0
TLS3_k127_4214032_20 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 434.0
TLS3_k127_4214032_21 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 434.0
TLS3_k127_4214032_22 COG2148 Sugar transferases involved in lipopolysaccharide synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 424.0
TLS3_k127_4214032_23 polysaccharide deactylase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 411.0
TLS3_k127_4214032_24 Glycosyl transferases group 1 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 413.0
TLS3_k127_4214032_25 O-Antigen ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 404.0
TLS3_k127_4214032_26 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009746 388.0
TLS3_k127_4214032_27 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 385.0
TLS3_k127_4214032_28 COG3267 Type II secretory pathway, component ExeA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 353.0
TLS3_k127_4214032_29 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 334.0
TLS3_k127_4214032_3 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 2.621e-234 739.0
TLS3_k127_4214032_30 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 331.0
TLS3_k127_4214032_31 Threonyl alanyl tRNA synthetase K07050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 320.0
TLS3_k127_4214032_32 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 313.0
TLS3_k127_4214032_33 COG0438 Glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 320.0
TLS3_k127_4214032_34 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 306.0
TLS3_k127_4214032_35 AAA domain K08252,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001772 283.0
TLS3_k127_4214032_36 PFAM ABC transporter related K01995,K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002286 286.0
TLS3_k127_4214032_37 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006286 287.0
TLS3_k127_4214032_38 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003497 269.0
TLS3_k127_4214032_39 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007679 269.0
TLS3_k127_4214032_4 ABC transporter transmembrane region K18890 - - 1.545e-229 724.0
TLS3_k127_4214032_40 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000008859 250.0
TLS3_k127_4214032_41 transferase activity, transferring glycosyl groups K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000008792 246.0
TLS3_k127_4214032_42 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000005845 233.0
TLS3_k127_4214032_43 (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003742 231.0
TLS3_k127_4214032_44 ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000000006233 231.0
TLS3_k127_4214032_45 Protein of unknown function (DUF1631) - - - 0.000000000000000000000000000000000000000000000000000000000006762 234.0
TLS3_k127_4214032_46 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000002411 201.0
TLS3_k127_4214032_47 glycosylase K03649 - 3.2.2.28 0.00000000000000000000000000000000000000000000000000000002782 201.0
TLS3_k127_4214032_48 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000006731 205.0
TLS3_k127_4214032_49 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000000000000000004417 196.0
TLS3_k127_4214032_5 ABC transporter transmembrane region K18889 - - 1.849e-229 734.0
TLS3_k127_4214032_50 Protein of unknown function (DUF1631) - - - 0.00000000000000000000000000000000000000000000000002785 204.0
TLS3_k127_4214032_51 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000000006726 162.0
TLS3_k127_4214032_52 Gram-negative-bacterium-type cell outer membrane assembly K21572 - - 0.00000000000000000000000000000000000000002544 158.0
TLS3_k127_4214032_53 Copper resistance protein D - - - 0.0000000000000000000000000000000000001336 147.0
TLS3_k127_4214032_54 acyl-coA-binding protein - - - 0.00000000000000000000000000000007694 134.0
TLS3_k127_4214032_55 Cytochrome c - - - 0.0000000000000000000000001451 113.0
TLS3_k127_4214032_56 cytochrome - - - 0.000000000000000000000005251 110.0
TLS3_k127_4214032_57 TIGRFAM PEP-CTERM system associated protein - - - 0.00000000000000000000008014 113.0
TLS3_k127_4214032_58 regulation of single-species biofilm formation K13572 - - 0.00000000000000009543 85.0
TLS3_k127_4214032_59 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.0000000000001046 81.0
TLS3_k127_4214032_6 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 1.308e-215 679.0
TLS3_k127_4214032_61 - - - - 0.00000006674 57.0
TLS3_k127_4214032_7 Branched-chain amino acid transport system / permease component K01997,K01998 - - 2.265e-203 649.0
TLS3_k127_4214032_8 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 1.458e-201 634.0
TLS3_k127_4214032_9 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 596.0
TLS3_k127_4290390_0 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009534 579.0
TLS3_k127_4290390_1 ACT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 537.0
TLS3_k127_4290390_10 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 365.0
TLS3_k127_4290390_11 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 306.0
TLS3_k127_4290390_12 response regulator receiver K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 293.0
TLS3_k127_4290390_13 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 289.0
TLS3_k127_4290390_14 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001433 286.0
TLS3_k127_4290390_15 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000006507 238.0
TLS3_k127_4290390_16 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000006837 227.0
TLS3_k127_4290390_17 DoxX family K15977 - - 0.00000000000000000000000000000000000000000000005436 172.0
TLS3_k127_4290390_18 Pilin (bacterial filament) K02650 - - 0.0000000000000000000000000000000000000000000001713 174.0
TLS3_k127_4290390_19 Cupin domain - - - 0.0000000000000000000000000000000000000000001742 166.0
TLS3_k127_4290390_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 548.0
TLS3_k127_4290390_20 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000001607 167.0
TLS3_k127_4290390_21 Domain of unknown function (DUF4154) - - - 0.000000000000000000000000000000001811 140.0
TLS3_k127_4290390_22 DoxX - - - 0.00000000000000000000000000000002066 131.0
TLS3_k127_4290390_23 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000005832 131.0
TLS3_k127_4290390_3 Flotillin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 509.0
TLS3_k127_4290390_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 424.0
TLS3_k127_4290390_5 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 425.0
TLS3_k127_4290390_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 418.0
TLS3_k127_4290390_7 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 429.0
TLS3_k127_4290390_8 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 424.0
TLS3_k127_4290390_9 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009965 393.0
TLS3_k127_4298382_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 304.0
TLS3_k127_4298382_1 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.000000000000000000000000006797 115.0
TLS3_k127_4316212_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 602.0
TLS3_k127_4316212_1 Dehydrogenase K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000006288 198.0
TLS3_k127_4316212_2 2'-5' RNA ligase superfamily - - - 0.00002984 52.0
TLS3_k127_4362440_0 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000594 291.0
TLS3_k127_4362440_1 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000137 137.0
TLS3_k127_4379598_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.055e-321 991.0
TLS3_k127_4379598_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 3.584e-246 774.0
TLS3_k127_4379598_10 taurine ABC transporter, periplasmic binding protein K15551 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 404.0
TLS3_k127_4379598_11 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 400.0
TLS3_k127_4379598_12 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 391.0
TLS3_k127_4379598_13 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 392.0
TLS3_k127_4379598_14 Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system K10831 - 3.6.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 374.0
TLS3_k127_4379598_15 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 360.0
TLS3_k127_4379598_16 reductase K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 332.0
TLS3_k127_4379598_17 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 330.0
TLS3_k127_4379598_18 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 331.0
TLS3_k127_4379598_19 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 329.0
TLS3_k127_4379598_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.302e-213 669.0
TLS3_k127_4379598_20 malonyl CoA-acyl carrier protein transacylase K00645,K15355 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 290.0
TLS3_k127_4379598_21 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001525 281.0
TLS3_k127_4379598_22 negative regulator of sigma E activity K03598 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001095 259.0
TLS3_k127_4379598_23 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000016 244.0
TLS3_k127_4379598_24 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000002879 244.0
TLS3_k127_4379598_25 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002197 232.0
TLS3_k127_4379598_26 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000001313 188.0
TLS3_k127_4379598_27 - - - - 0.00000000000000000000000000000000000000000000021 174.0
TLS3_k127_4379598_28 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000001375 160.0
TLS3_k127_4379598_29 Protein of unknown function (DUF1178) - - - 0.000000000000000000000000000000000000000378 156.0
TLS3_k127_4379598_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 1.252e-204 643.0
TLS3_k127_4379598_30 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000002358 133.0
TLS3_k127_4379598_31 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000002651 139.0
TLS3_k127_4379598_32 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000001051 138.0
TLS3_k127_4379598_33 - - - - 0.00000000000000000000000000002973 129.0
TLS3_k127_4379598_34 Domain of unknown function (DUF4845) - - - 0.000000000000000000000002098 110.0
TLS3_k127_4379598_35 ThiS family - - - 0.00000000000000000000006646 102.0
TLS3_k127_4379598_37 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.000000001343 66.0
TLS3_k127_4379598_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 584.0
TLS3_k127_4379598_5 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 531.0
TLS3_k127_4379598_6 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 490.0
TLS3_k127_4379598_7 binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009142 433.0
TLS3_k127_4379598_8 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 430.0
TLS3_k127_4379598_9 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 413.0
TLS3_k127_4402600_0 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 498.0
TLS3_k127_4402600_1 PFAM ABC transporter related K02028,K09972 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 417.0
TLS3_k127_4402600_2 acid transport system permease K09970 - - 0.0000000000000000000000000000000000000000002229 160.0
TLS3_k127_4402600_3 - - - - 0.0000000000000000000000000000000007151 136.0
TLS3_k127_4440653_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0000226,GO:0001817,GO:0001819,GO:0001906,GO:0001907,GO:0002376,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004365,GO:0004857,GO:0004866,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005811,GO:0005829,GO:0005856,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006417,GO:0006464,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007010,GO:0007017,GO:0008017,GO:0008092,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009605,GO:0009607,GO:0009620,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010506,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0012505,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016241,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016769,GO:0016903,GO:0017014,GO:0017144,GO:0017148,GO:0018119,GO:0018130,GO:0018193,GO:0018198,GO:0019222,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019730,GO:0019752,GO:0019828,GO:0019904,GO:0030162,GO:0030234,GO:0030414,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031341,GO:0031343,GO:0031640,GO:0031647,GO:0031965,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032787,GO:0032879,GO:0032880,GO:0032991,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035605,GO:0035606,GO:0035821,GO:0036094,GO:0036211,GO:0042221,GO:0042802,GO:0042866,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043436,GO:0043891,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0045087,GO:0045861,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050662,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050832,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051287,GO:0051336,GO:0051346,GO:0051402,GO:0051701,GO:0051702,GO:0051704,GO:0051707,GO:0051709,GO:0051712,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0052040,GO:0052042,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0061134,GO:0061135,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070887,GO:0070997,GO:0071310,GO:0071345,GO:0071346,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097159,GO:0097452,GO:0097718,GO:0098542,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:1990904,GO:2000112,GO:2000113 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 583.0
TLS3_k127_4440653_1 Belongs to the transketolase family K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 461.0
TLS3_k127_4481180_0 benzoyl-CoA oxygenase K15512 - 1.14.13.208 1.186e-256 796.0
TLS3_k127_4481180_1 GMC oxidoreductase K00108 - 1.1.99.1 8.719e-237 751.0
TLS3_k127_4481180_10 NADH:flavin oxidoreductase / NADH oxidase family K09461 - 1.14.13.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 329.0
TLS3_k127_4481180_11 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 319.0
TLS3_k127_4481180_12 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 284.0
TLS3_k127_4481180_13 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000008262 222.0
TLS3_k127_4481180_14 spore germination - - - 0.0000000000000000000000000000000000000000000000000000000002712 213.0
TLS3_k127_4481180_15 Acyl dehydratase - - - 0.000000000000000000000000000000000000000000000000000000151 198.0
TLS3_k127_4481180_16 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000004096 177.0
TLS3_k127_4481180_17 Protein of unknown function (DUF1622) - - - 0.00000000000000000000000000000000000000007345 154.0
TLS3_k127_4481180_18 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000002087 151.0
TLS3_k127_4481180_2 PFAM Acyl-CoA dehydrogenase K00252 - 1.3.8.6 2.639e-222 696.0
TLS3_k127_4481180_3 Oxidoreductase NAD-binding domain K15511 - 1.14.13.208 1.27e-196 619.0
TLS3_k127_4481180_4 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 502.0
TLS3_k127_4481180_5 D-arabinono-1,4-lactone oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 441.0
TLS3_k127_4481180_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 427.0
TLS3_k127_4481180_7 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 391.0
TLS3_k127_4481180_8 enoyl-coa hydratase carnithine racemase K15513 - 4.1.2.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 369.0
TLS3_k127_4481180_9 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 356.0
TLS3_k127_4506374_0 abc transporter atp-binding protein K06147 - - 5.183e-295 918.0
TLS3_k127_4506374_1 FAD binding domain K05712 - 1.14.13.127 5.93e-206 653.0
TLS3_k127_4506374_10 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 306.0
TLS3_k127_4506374_11 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 291.0
TLS3_k127_4506374_12 4-phosphoerythronate dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002586 274.0
TLS3_k127_4506374_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002858 247.0
TLS3_k127_4506374_14 Protein of unknown function (DUF3014) - - - 0.000000000000000000000000000000000000000000000000000000000000001025 228.0
TLS3_k127_4506374_15 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000001009 219.0
TLS3_k127_4506374_16 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000002831 196.0
TLS3_k127_4506374_17 Protein of unknown function (DUF1810) - - - 0.0000000000000000000000000000000000000000000000000000117 194.0
TLS3_k127_4506374_18 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000005398 184.0
TLS3_k127_4506374_19 Low affinity iron permease - - - 0.000000000000000000000000000000000000000000003086 168.0
TLS3_k127_4506374_2 Homospermidine synthase K00808 - 2.5.1.44 2.248e-205 649.0
TLS3_k127_4506374_20 MAPEG family - - - 0.00000000000000000000000000000000001249 140.0
TLS3_k127_4506374_21 - - - - 0.0000000000002986 79.0
TLS3_k127_4506374_3 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 525.0
TLS3_k127_4506374_4 e3 binding domain K09699 - 2.3.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 478.0
TLS3_k127_4506374_5 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 417.0
TLS3_k127_4506374_6 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 386.0
TLS3_k127_4506374_7 Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 366.0
TLS3_k127_4506374_8 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 312.0
TLS3_k127_4506374_9 NAD-dependent epimerase dehydratase K18981 - 1.1.1.203 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 305.0
TLS3_k127_4514425_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 3.139e-314 970.0
TLS3_k127_4514425_1 abc transporter K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 505.0
TLS3_k127_4514425_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000001301 188.0
TLS3_k127_4514425_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000000000002679 154.0
TLS3_k127_4542562_0 Soluble lytic murein K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 599.0
TLS3_k127_4542562_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 441.0
TLS3_k127_4542562_10 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 294.0
TLS3_k127_4542562_11 lipid A biosynthesis acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004613 260.0
TLS3_k127_4542562_12 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000003271 246.0
TLS3_k127_4542562_13 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004432 253.0
TLS3_k127_4542562_14 Transcriptional regulator K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000002444 241.0
TLS3_k127_4542562_15 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000004301 193.0
TLS3_k127_4542562_16 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000000000000000008989 181.0
TLS3_k127_4542562_17 Beta-ketoacyl synthase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000002254 184.0
TLS3_k127_4542562_18 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000006708 174.0
TLS3_k127_4542562_19 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000163 170.0
TLS3_k127_4542562_2 cystathionine K01758 - 4.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 437.0
TLS3_k127_4542562_21 - - - - 0.00000000000000000000000000000001422 140.0
TLS3_k127_4542562_22 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000006441 135.0
TLS3_k127_4542562_23 Domain of unknown function (DUF4112) - - - 0.000000000000000000000000000499 118.0
TLS3_k127_4542562_24 Phosphopantetheine attachment site K02078 - - 0.00000000000000000000000003212 109.0
TLS3_k127_4542562_25 dehydratase - - - 0.000000000000000000000003522 107.0
TLS3_k127_4542562_26 MMPL family - - - 0.00000000000000000002442 101.0
TLS3_k127_4542562_27 Protein of unknown function (DUF2905) - - - 0.0000000000000001835 80.0
TLS3_k127_4542562_28 Protein of unknown function (DUF3144) - - - 0.000000003888 67.0
TLS3_k127_4542562_29 - - - - 0.00000109 61.0
TLS3_k127_4542562_3 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 466.0
TLS3_k127_4542562_30 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.00001029 56.0
TLS3_k127_4542562_4 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 399.0
TLS3_k127_4542562_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 375.0
TLS3_k127_4542562_6 Nad-dependent epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 349.0
TLS3_k127_4542562_7 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 342.0
TLS3_k127_4542562_8 Psort location Cytoplasmic, score 9.97 K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 334.0
TLS3_k127_4542562_9 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 301.0
TLS3_k127_4544783_0 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 298.0
TLS3_k127_4544783_1 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.0000000000000000000000000000000000000000000000002265 178.0
TLS3_k127_4544783_2 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000000000000000000000000001212 147.0
TLS3_k127_4544783_3 cystathionine K01758 - 4.4.1.1 0.00000000000000000000000000000668 121.0
TLS3_k127_4544783_4 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000001318 75.0
TLS3_k127_4544783_5 - - - - 0.0000003287 64.0
TLS3_k127_4544783_6 Domain of unknown function (DUF4440) - - - 0.00001745 50.0
TLS3_k127_4560837_0 Prokaryotic cytochrome b561 K03620 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000166 248.0
TLS3_k127_4560837_1 PFAM HupH hydrogenase expression protein K03618 - - 0.0000000000000000000000000000000000000000000000000000000000000000004152 244.0
TLS3_k127_4560837_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000144 225.0
TLS3_k127_4560837_3 hydrogenase expression formation protein K03605 - - 0.00000000000000000000000000000000000000000000000000000000001938 213.0
TLS3_k127_4560837_4 Hydrogenase-1 expression protein HyaE K03619 - - 0.0000000000000000000000000000000008484 139.0
TLS3_k127_4560837_5 Helix-turn-helix K21498 - - 0.0000000000000000000000000133 113.0
TLS3_k127_4560837_6 HupF/HypC family K04653 - - 0.0000000000000000000006507 98.0
TLS3_k127_4585717_0 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 370.0
TLS3_k127_4585717_1 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000016 224.0
TLS3_k127_4585717_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000008141 134.0
TLS3_k127_4585717_3 Belongs to the HpcH HpaI aldolase family K00979,K02510 - 2.7.7.38,4.1.2.52 0.000000005574 58.0
TLS3_k127_4601073_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 2.518e-248 783.0
TLS3_k127_4601073_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 2.055e-195 625.0
TLS3_k127_4601073_10 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 509.0
TLS3_k127_4601073_11 Multidrug ABC transporter ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 496.0
TLS3_k127_4601073_12 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 474.0
TLS3_k127_4601073_13 oxidoreductase FAD NAD(P)-binding domain protein K00523,K18248 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 461.0
TLS3_k127_4601073_14 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 447.0
TLS3_k127_4601073_15 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 424.0
TLS3_k127_4601073_16 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009802 423.0
TLS3_k127_4601073_17 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 412.0
TLS3_k127_4601073_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 411.0
TLS3_k127_4601073_19 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 412.0
TLS3_k127_4601073_2 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 591.0
TLS3_k127_4601073_20 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 401.0
TLS3_k127_4601073_21 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 362.0
TLS3_k127_4601073_22 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 353.0
TLS3_k127_4601073_23 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 332.0
TLS3_k127_4601073_24 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 325.0
TLS3_k127_4601073_25 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009576 313.0
TLS3_k127_4601073_26 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 297.0
TLS3_k127_4601073_27 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 289.0
TLS3_k127_4601073_28 Major facilitator superfamily K07552,K18552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001302 282.0
TLS3_k127_4601073_29 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002151 277.0
TLS3_k127_4601073_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 592.0
TLS3_k127_4601073_30 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000004151 233.0
TLS3_k127_4601073_31 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000149 224.0
TLS3_k127_4601073_32 HAD-superfamily hydrolase, subfamily IB (PSPase-like) - - - 0.000000000000000000000000000000000000000000000000000000000000003747 223.0
TLS3_k127_4601073_33 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000000000001691 183.0
TLS3_k127_4601073_34 Cytochrome B561 - - - 0.0000000000000000000000000000000000000000000000007772 182.0
TLS3_k127_4601073_35 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000000000000000000000000000000000000000000001577 181.0
TLS3_k127_4601073_36 Belongs to the DnaA family K10763 - - 0.00000000000000000000000000000000000000000000001211 178.0
TLS3_k127_4601073_37 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000001612 176.0
TLS3_k127_4601073_38 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000001088 167.0
TLS3_k127_4601073_39 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000000000000000000004424 154.0
TLS3_k127_4601073_4 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 570.0
TLS3_k127_4601073_40 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.000000000000000000000000000000000000002457 156.0
TLS3_k127_4601073_41 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000001199 151.0
TLS3_k127_4601073_42 Belongs to the acetyltransferase family. ArgA subfamily K00537,K00619,K07755 - 1.20.4.1,2.1.1.137,2.3.1.1 0.00000000000000000000000000000000000003952 148.0
TLS3_k127_4601073_43 PFAM Secreted repeat of - - - 0.0000000000000000000000000000000000006005 143.0
TLS3_k127_4601073_44 Preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000000006502 126.0
TLS3_k127_4601073_45 PFAM cytochrome c - - - 0.0000000000000000000000000006155 119.0
TLS3_k127_4601073_46 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000000003029 96.0
TLS3_k127_4601073_47 phosphorelay signal transduction system K02535 - 3.5.1.108 0.000000279 63.0
TLS3_k127_4601073_5 Major facilitator superfamily K08167 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 574.0
TLS3_k127_4601073_6 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006216 569.0
TLS3_k127_4601073_7 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 569.0
TLS3_k127_4601073_8 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 539.0
TLS3_k127_4601073_9 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 529.0
TLS3_k127_460238_0 Malic enzyme K00029 - 1.1.1.40 0.0 1125.0
TLS3_k127_460238_1 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 1.588e-263 819.0
TLS3_k127_460238_10 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000003777 269.0
TLS3_k127_460238_11 Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000000000000000000000000000003173 220.0
TLS3_k127_460238_12 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.0000000000000000000000000000000000000000000000000000000000006727 220.0
TLS3_k127_460238_13 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000001919 211.0
TLS3_k127_460238_14 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000000000007345 202.0
TLS3_k127_460238_15 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000001379 203.0
TLS3_k127_460238_16 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000001223 187.0
TLS3_k127_460238_17 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000232 168.0
TLS3_k127_460238_18 mRNA catabolic process - - - 0.000000000000000000000000000000000002249 146.0
TLS3_k127_460238_19 KTSC domain - - - 0.00000000000000000000000001897 111.0
TLS3_k127_460238_2 Biotin carboxylase K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 2.057e-243 757.0
TLS3_k127_460238_3 RNB K01147 - 3.1.13.1 2.731e-219 699.0
TLS3_k127_460238_4 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 593.0
TLS3_k127_460238_5 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 572.0
TLS3_k127_460238_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 455.0
TLS3_k127_460238_7 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 338.0
TLS3_k127_460238_8 Belongs to the transketolase family K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 301.0
TLS3_k127_460238_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 300.0
TLS3_k127_461391_0 Transport of potassium into the cell K03549 - - 1.799e-218 696.0
TLS3_k127_461391_1 TonB dependent receptor - - - 1.354e-202 663.0
TLS3_k127_461391_10 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.0000000000000000003826 90.0
TLS3_k127_461391_11 Pfam Response regulator receiver K02483 - - 0.00000000000000001202 95.0
TLS3_k127_461391_12 PFAM helix-turn-helix- domain containing protein AraC type K07506 - - 0.0000000003787 71.0
TLS3_k127_461391_2 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 625.0
TLS3_k127_461391_3 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 474.0
TLS3_k127_461391_4 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 314.0
TLS3_k127_461391_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000001356 149.0
TLS3_k127_461391_6 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000001199 126.0
TLS3_k127_461391_7 transcriptional regulator - - - 0.0000000000000000000007641 102.0
TLS3_k127_461391_8 Protein of unknown function (DUF3999) - - - 0.00000000000000000003509 106.0
TLS3_k127_461391_9 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000005263 95.0
TLS3_k127_4646053_0 PFAM AMP-dependent synthetase and ligase K00666 - - 1.164e-262 819.0
TLS3_k127_4646053_1 Aminotransferase class-III K00819,K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.13,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 488.0
TLS3_k127_4646053_2 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 416.0
TLS3_k127_4646053_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 415.0
TLS3_k127_4646053_4 PFAM Enoyl-CoA hydratase isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008146 380.0
TLS3_k127_4646053_5 Amidinotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001297 301.0
TLS3_k127_4646053_6 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000002024 143.0
TLS3_k127_4652606_0 Bacterial protein of unknown function (DUF839) K07093 - - 4.082e-230 730.0
TLS3_k127_4652606_1 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 438.0
TLS3_k127_4652606_2 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 309.0
TLS3_k127_4652606_3 Type VI secretion system effector, Hcp K11903 - - 0.0000000000000000000000000000000000000000000000003227 181.0
TLS3_k127_4652606_4 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000001407 123.0
TLS3_k127_4652606_5 SEC-C motif - - - 0.000000000000000001471 90.0
TLS3_k127_465891_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001188 270.0
TLS3_k127_465891_1 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000005958 192.0
TLS3_k127_465891_2 Protein of unknown function (DUF3500) - - - 0.000000005111 62.0
TLS3_k127_466348_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 7.858e-239 747.0
TLS3_k127_466348_1 Membrane protease subunits, stomatin prohibitin homologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008453 446.0
TLS3_k127_466348_2 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000000000008948 215.0
TLS3_k127_466348_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000001203 163.0
TLS3_k127_466348_4 Domain of unknown function (DUF4124) - - - 0.000000000000000000000003604 110.0
TLS3_k127_466348_5 Belongs to the UPF0125 (RnfH) family K09801 - - 0.000000000000000443 83.0
TLS3_k127_466348_6 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0007747 43.0
TLS3_k127_4694497_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 566.0
TLS3_k127_4694497_1 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 324.0
TLS3_k127_4694497_2 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006339 248.0
TLS3_k127_4694497_3 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000001742 217.0
TLS3_k127_4694497_4 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000001442 147.0
TLS3_k127_4694497_5 dehydrogenase - - - 0.000000000000000000000000000000008221 127.0
TLS3_k127_4694497_6 - - - - 0.0009028 47.0
TLS3_k127_4708783_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 5.451e-318 987.0
TLS3_k127_4708783_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 308.0
TLS3_k127_4708783_2 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002944 251.0
TLS3_k127_4708783_3 Peptidase M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000002583 236.0
TLS3_k127_4708783_4 PAS domain containing protein K07716 - 2.7.13.3 0.00000004483 60.0
TLS3_k127_4714834_0 Transcriptional regulator K03603,K05799 - - 2.272e-233 755.0
TLS3_k127_4714834_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 5.827e-233 740.0
TLS3_k127_4714834_10 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 402.0
TLS3_k127_4714834_11 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 374.0
TLS3_k127_4714834_12 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 360.0
TLS3_k127_4714834_13 Mg2 and Co2 transporter K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 357.0
TLS3_k127_4714834_14 COG1538 Outer membrane protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 354.0
TLS3_k127_4714834_15 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 300.0
TLS3_k127_4714834_16 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003291 279.0
TLS3_k127_4714834_17 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000008521 263.0
TLS3_k127_4714834_18 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000007209 237.0
TLS3_k127_4714834_19 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000000000000000000005735 226.0
TLS3_k127_4714834_2 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 3.225e-220 706.0
TLS3_k127_4714834_20 rhodanese-related sulfurtransferase - - - 0.00000000000000000000000000000000000000004682 154.0
TLS3_k127_4714834_21 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000008977 143.0
TLS3_k127_4714834_22 - - - - 0.0002564 48.0
TLS3_k127_4714834_23 Nucleotidyl transferase K00992 - 2.7.7.99 0.0009684 46.0
TLS3_k127_4714834_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 2.325e-218 685.0
TLS3_k127_4714834_4 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 526.0
TLS3_k127_4714834_5 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 459.0
TLS3_k127_4714834_6 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 442.0
TLS3_k127_4714834_7 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 431.0
TLS3_k127_4714834_8 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 410.0
TLS3_k127_4714834_9 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 398.0
TLS3_k127_4729471_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 3.646e-208 654.0
TLS3_k127_4729471_1 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 552.0
TLS3_k127_4729471_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 540.0
TLS3_k127_4729471_3 3'-5' exonuclease K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 373.0
TLS3_k127_4729471_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000006533 243.0
TLS3_k127_4729471_5 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000002086 211.0
TLS3_k127_4729471_6 Tetratricopeptide repeat K02656 - - 0.000000000000000000000000000000000000000000000000000000006892 209.0
TLS3_k127_4729471_7 peptidase K06194 - - 0.0000000000000000000000000000000000000000000000006489 180.0
TLS3_k127_4729471_8 Domain of unknown function (DUF4115) K15539 - - 0.00000000000000000000000000000069 133.0
TLS3_k127_474154_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 464.0
TLS3_k127_474154_1 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 325.0
TLS3_k127_474154_2 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000001094 150.0
TLS3_k127_474154_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000009457 119.0
TLS3_k127_4774110_0 PQQ-like domain K00117 - 1.1.5.2 0.0 1343.0
TLS3_k127_4774110_1 Cytochrome C and Quinol oxidase polypeptide I K15408 - 1.9.3.1 0.0 1116.0
TLS3_k127_4774110_10 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000007008 110.0
TLS3_k127_4774110_11 - - - - 0.000000000009235 74.0
TLS3_k127_4774110_12 - - - - 0.00000001169 64.0
TLS3_k127_4774110_2 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 469.0
TLS3_k127_4774110_3 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 451.0
TLS3_k127_4774110_4 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 395.0
TLS3_k127_4774110_5 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 334.0
TLS3_k127_4774110_6 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 336.0
TLS3_k127_4774110_7 Predicted membrane protein (DUF2231) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002328 275.0
TLS3_k127_4774110_8 Cytochrome C oxidase subunit II, periplasmic domain K02275,K02826 - 1.10.3.12,1.9.3.1 0.0000000000000000000000000000000000000000000000000000000001168 219.0
TLS3_k127_4774110_9 Uncharacterised protein family (UPF0093) - - - 0.0000000000000000000000000000000000000000378 156.0
TLS3_k127_4793799_0 Conserved carboxylase domain K01571 - 4.1.1.3 2.629e-236 738.0
TLS3_k127_4793799_1 Ring hydroxylating alpha subunit (catalytic domain) - - - 2.185e-196 618.0
TLS3_k127_4793799_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 9.634e-196 621.0
TLS3_k127_4793799_3 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 597.0
TLS3_k127_4793799_4 Winged helix DNA-binding domain K09927 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 509.0
TLS3_k127_4793799_5 Transcriptional regulator K02624 - - 0.00000000000000000000000000000000000000000000000003569 185.0
TLS3_k127_4793799_6 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000005453 166.0
TLS3_k127_4793799_7 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000001768 161.0
TLS3_k127_4793799_8 von Willebrand factor (vWF) type A domain K07114 - - 0.0001095 50.0
TLS3_k127_4827590_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 3.62e-283 898.0
TLS3_k127_4827590_1 Belongs to the malate synthase family K01638 - 2.3.3.9 1.027e-278 864.0
TLS3_k127_4827590_10 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 431.0
TLS3_k127_4827590_11 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 424.0
TLS3_k127_4827590_12 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 381.0
TLS3_k127_4827590_13 Protein of unknown function (DUF2863) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003161 287.0
TLS3_k127_4827590_14 Haloacid dehalogenase, type II K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000002487 233.0
TLS3_k127_4827590_15 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000008734 228.0
TLS3_k127_4827590_16 Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000001483 228.0
TLS3_k127_4827590_17 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000001484 224.0
TLS3_k127_4827590_18 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000004409 211.0
TLS3_k127_4827590_19 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000007963 183.0
TLS3_k127_4827590_2 Isocitrate lyase K01637 - 4.1.3.1 2.644e-247 767.0
TLS3_k127_4827590_20 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000002006 143.0
TLS3_k127_4827590_21 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000001032 124.0
TLS3_k127_4827590_22 Malonyl CoA-acyl carrier protein transacylase K00645,K15355 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.00000000000000000000000000005513 118.0
TLS3_k127_4827590_23 Ribosomal L32p protein family K02911 - - 0.00000000000000000000000000008063 117.0
TLS3_k127_4827590_3 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 571.0
TLS3_k127_4827590_4 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 522.0
TLS3_k127_4827590_5 Malate/L-lactate dehydrogenase K16844 - 1.1.1.338 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 516.0
TLS3_k127_4827590_6 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 491.0
TLS3_k127_4827590_7 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 479.0
TLS3_k127_4827590_8 5'-nucleotidase, C-terminal domain K01081,K11751 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006213,GO:0006259,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007155,GO:0007159,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009164,GO:0009166,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019362,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0022610,GO:0031974,GO:0031981,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046135,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0072524,GO:0072527,GO:0072529,GO:0090304,GO:0098609,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 479.0
TLS3_k127_4827590_9 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 432.0
TLS3_k127_5101062_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1281.0
TLS3_k127_5101062_1 DNA helicase K03657 - 3.6.4.12 2.837e-266 874.0
TLS3_k127_5101062_10 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000006125 222.0
TLS3_k127_5101062_11 PFAM conserved K08973 - - 0.0000000000000000000000000000000000000000000000000001408 190.0
TLS3_k127_5101062_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000001975 153.0
TLS3_k127_5101062_13 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000000000005998 147.0
TLS3_k127_5101062_14 - - - - 0.000000000000000000000000000000007836 138.0
TLS3_k127_5101062_15 - - - - 0.0000000000000000007257 98.0
TLS3_k127_5101062_16 heat shock protein binding - - - 0.00000000000000008308 82.0
TLS3_k127_5101062_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 582.0
TLS3_k127_5101062_3 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 447.0
TLS3_k127_5101062_4 THUMP domain K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 420.0
TLS3_k127_5101062_5 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 374.0
TLS3_k127_5101062_6 DNA polymerase III (Delta subunit) K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 347.0
TLS3_k127_5101062_7 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 338.0
TLS3_k127_5101062_8 Type II/IV secretion system protein K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 331.0
TLS3_k127_5101062_9 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000004401 252.0
TLS3_k127_5134969_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 500.0
TLS3_k127_5134969_1 Branched-chain amino acid transport protein (AzlD) - - - 0.0000000000000000000000003405 108.0
TLS3_k127_5134969_2 Branched-chain amino acid permease - - - 0.00002301 49.0
TLS3_k127_5146191_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1543.0
TLS3_k127_5146191_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 1.508e-303 933.0
TLS3_k127_5181164_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.05e-251 777.0
TLS3_k127_5181164_1 Prolyl oligopeptidase K01322 - 3.4.21.26 7.001e-247 782.0
TLS3_k127_5181164_10 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000003401 113.0
TLS3_k127_5181164_2 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 464.0
TLS3_k127_5181164_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 324.0
TLS3_k127_5181164_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 320.0
TLS3_k127_5181164_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 309.0
TLS3_k127_5181164_6 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002018 268.0
TLS3_k127_5181164_7 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000003583 236.0
TLS3_k127_5181164_8 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000124 202.0
TLS3_k127_5181164_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000008432 196.0
TLS3_k127_5186795_0 ABC-type sugar transport system, periplasmic component K05813 - - 1.167e-239 751.0
TLS3_k127_5186795_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 334.0
TLS3_k127_5186795_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000001158 160.0
TLS3_k127_5186795_3 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000001202 117.0
TLS3_k127_5194113_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2262.0
TLS3_k127_5194113_1 CHAT domain - - - 0.0 1889.0
TLS3_k127_5194113_10 Bile acid K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 413.0
TLS3_k127_5194113_11 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 415.0
TLS3_k127_5194113_12 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 422.0
TLS3_k127_5194113_13 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 424.0
TLS3_k127_5194113_14 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009214 380.0
TLS3_k127_5194113_15 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 380.0
TLS3_k127_5194113_16 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 335.0
TLS3_k127_5194113_17 Ami_2 K01447 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 302.0
TLS3_k127_5194113_18 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 295.0
TLS3_k127_5194113_19 TIR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003949 239.0
TLS3_k127_5194113_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 5.015e-312 975.0
TLS3_k127_5194113_20 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000000000000000000000003385 199.0
TLS3_k127_5194113_21 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000006489 192.0
TLS3_k127_5194113_22 - - - - 0.00000000000000000000000000000000000000000000006126 189.0
TLS3_k127_5194113_23 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000003401 135.0
TLS3_k127_5194113_24 TIR domain - - - 0.0000000000000000000000000000401 129.0
TLS3_k127_5194113_25 TIR domain - - - 0.000000000000000000000000001693 125.0
TLS3_k127_5194113_26 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000001149 113.0
TLS3_k127_5194113_27 pathogenesis - - - 0.0000000000000001451 88.0
TLS3_k127_5194113_28 - - - - 0.000000000000001526 83.0
TLS3_k127_5194113_29 T4-like virus tail tube protein gp19 - - - 0.000000000000004005 82.0
TLS3_k127_5194113_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 9.523e-268 833.0
TLS3_k127_5194113_4 2-aminobenzoate-CoA ligase K08295 - 6.2.1.32 1.019e-234 737.0
TLS3_k127_5194113_5 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 6.634e-215 679.0
TLS3_k127_5194113_6 involved in the beta-oxidation of n-alkanoic and n-phenylalkanoic acids K01897 - 6.2.1.3 1.554e-212 675.0
TLS3_k127_5194113_7 amidohydrolase K01451 - 3.5.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 550.0
TLS3_k127_5194113_8 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 492.0
TLS3_k127_5194113_9 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 430.0
TLS3_k127_5221182_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 2.649e-220 694.0
TLS3_k127_5221182_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009639 371.0
TLS3_k127_5221182_2 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000001595 233.0
TLS3_k127_5221182_3 TIGRFAM ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.000000000000000000000000000000000000000000000008322 173.0
TLS3_k127_5221182_4 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000000000009746 170.0
TLS3_k127_5221182_5 Fe-S assembly protein IscX - - - 0.00000000000000000000000003724 111.0
TLS3_k127_5221182_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000004241 93.0
TLS3_k127_522155_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 362.0
TLS3_k127_522155_1 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006173 278.0
TLS3_k127_522155_2 Large extracellular alpha-helical protein - - - 0.00000000000000000000000000000000000000000000000000203 203.0
TLS3_k127_522155_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000001399 183.0
TLS3_k127_522155_4 Secretin and TonB N terminus short domain K02666 - - 0.0000002234 52.0
TLS3_k127_5227961_0 ABC-type Fe3 transport system permease component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 576.0
TLS3_k127_5227961_1 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 407.0
TLS3_k127_5227961_2 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 370.0
TLS3_k127_5227961_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000003684 186.0
TLS3_k127_5227961_4 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000004034 126.0
TLS3_k127_5227961_5 Nitrilase K01501 - 3.5.5.1 0.0000001536 53.0
TLS3_k127_5239457_0 Phytanoyl-CoA dioxygenase (PhyH) K10674 - 1.14.11.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 524.0
TLS3_k127_5239457_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 518.0
TLS3_k127_5239457_10 peptidase S1 and S6, chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 309.0
TLS3_k127_5239457_11 ABC-type RTX toxin transporter, ATPase and permease components Prot1E family K13409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 303.0
TLS3_k127_5239457_12 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000683 286.0
TLS3_k127_5239457_13 HlyD family secretion protein K13408 - - 0.000000000000000000000000000000000000000000000000000000000000000000001761 252.0
TLS3_k127_5239457_14 Rhodanese-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000008956 236.0
TLS3_k127_5239457_15 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000006489 174.0
TLS3_k127_5239457_16 Glycine-zipper domain - - - 0.00000000000000000000000000000000007713 141.0
TLS3_k127_5239457_17 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000002286 138.0
TLS3_k127_5239457_18 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000000158 131.0
TLS3_k127_5239457_19 MgtC family K07507 - - 0.0000000000000000000000000000001227 130.0
TLS3_k127_5239457_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 503.0
TLS3_k127_5239457_20 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000002182 102.0
TLS3_k127_5239457_21 - - - - 0.000000000000000000007853 98.0
TLS3_k127_5239457_3 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 393.0
TLS3_k127_5239457_4 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 378.0
TLS3_k127_5239457_5 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 375.0
TLS3_k127_5239457_6 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 343.0
TLS3_k127_5239457_7 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 324.0
TLS3_k127_5239457_8 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 321.0
TLS3_k127_5239457_9 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 316.0
TLS3_k127_5242560_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.037e-203 640.0
TLS3_k127_5242560_1 amino acid K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 585.0
TLS3_k127_5242560_2 Beta-ketoacyl synthase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 582.0
TLS3_k127_5242560_3 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 579.0
TLS3_k127_5242560_4 Phenylacetate-CoA oxygenase subunit PaaA K02609 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 563.0
TLS3_k127_5242560_5 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 K02613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 488.0
TLS3_k127_5242560_6 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 287.0
TLS3_k127_5242560_7 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000003975 211.0
TLS3_k127_5242560_8 Phenylacetate-CoA oxygenase subunit PaaB K02610 - - 0.000000000000000000000000000000000000000000000000007847 181.0
TLS3_k127_5242560_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000001363 88.0
TLS3_k127_5248335_0 MCM2/3/5 family K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 445.0
TLS3_k127_5248335_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002967 244.0
TLS3_k127_5248335_2 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000000000000000003288 171.0
TLS3_k127_5248335_3 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000009238 135.0
TLS3_k127_5256753_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 0.0 1015.0
TLS3_k127_5256753_1 Receptor family ligand binding region K01999 - - 2.523e-194 614.0
TLS3_k127_5256753_10 DUF218 domain - - - 0.00000000000000000000000000000000000000000003177 173.0
TLS3_k127_5256753_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 510.0
TLS3_k127_5256753_3 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 479.0
TLS3_k127_5256753_4 Fatty acid hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 438.0
TLS3_k127_5256753_5 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 377.0
TLS3_k127_5256753_6 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004991 278.0
TLS3_k127_5256753_7 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000002456 218.0
TLS3_k127_5256753_8 Haem-degrading K11477 - - 0.000000000000000000000000000000000000000000000000001181 187.0
TLS3_k127_5256753_9 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000000000000000001338 174.0
TLS3_k127_5274717_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1423.0
TLS3_k127_5274717_1 Belongs to the GcvT family K00315,K19191 - 1.5.3.19,1.5.8.4 0.0 1191.0
TLS3_k127_5274717_10 Na Pi-cotransporter II-related protein K03324 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 578.0
TLS3_k127_5274717_11 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 558.0
TLS3_k127_5274717_12 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 547.0
TLS3_k127_5274717_13 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 505.0
TLS3_k127_5274717_14 alcohol dehydrogenase K13954 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 508.0
TLS3_k127_5274717_15 TIGRFAM 2-aminoethylphosphonate ABC transport system, 1-aminoethylphosphonate-binding protein component K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 498.0
TLS3_k127_5274717_16 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 464.0
TLS3_k127_5274717_17 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 459.0
TLS3_k127_5274717_18 Extracellular solute-binding protein, family 5 middle family protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008163 453.0
TLS3_k127_5274717_19 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 434.0
TLS3_k127_5274717_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 2.77e-240 760.0
TLS3_k127_5274717_20 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 409.0
TLS3_k127_5274717_21 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009065 419.0
TLS3_k127_5274717_22 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 413.0
TLS3_k127_5274717_23 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 398.0
TLS3_k127_5274717_24 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 386.0
TLS3_k127_5274717_25 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 383.0
TLS3_k127_5274717_26 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 397.0
TLS3_k127_5274717_27 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 364.0
TLS3_k127_5274717_28 Peptidase C26 K01658,K07010 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 349.0
TLS3_k127_5274717_29 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 346.0
TLS3_k127_5274717_3 Aldehyde dehydrogenase family - - - 5.929e-200 631.0
TLS3_k127_5274717_30 Phospholipase D. Active site motifs. K06132 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0090483,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 353.0
TLS3_k127_5274717_31 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 325.0
TLS3_k127_5274717_32 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 287.0
TLS3_k127_5274717_33 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000001141 271.0
TLS3_k127_5274717_34 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003801 265.0
TLS3_k127_5274717_35 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000006396 268.0
TLS3_k127_5274717_36 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000001118 263.0
TLS3_k127_5274717_37 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006933 274.0
TLS3_k127_5274717_38 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000774 258.0
TLS3_k127_5274717_39 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000001067 240.0
TLS3_k127_5274717_4 Acetolactate synthase K01577,K01652,K03852 - 2.2.1.6,2.3.3.15,4.1.1.8 8.355e-200 628.0
TLS3_k127_5274717_40 TIGRFAM phosphonate degradation operons associated HDIG domain protein K21196 - 1.13.11.78 0.0000000000000000000000000000000000000000000000000000000000000000164 228.0
TLS3_k127_5274717_41 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.00000000000000000000000000000000000000000000000000000000000004556 218.0
TLS3_k127_5274717_42 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000003045 214.0
TLS3_k127_5274717_43 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000000000004768 210.0
TLS3_k127_5274717_44 Pfam Sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000006032 212.0
TLS3_k127_5274717_45 PFAM peptidase S16 lon domain protein K07157 - - 0.0000000000000000000000000000000000000000000000000000001401 203.0
TLS3_k127_5274717_46 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000147 165.0
TLS3_k127_5274717_47 Tripartite ATP-independent periplasmic transporters, DctQ component K21394 - - 0.000000000000000000000000000000000000000007133 162.0
TLS3_k127_5274717_48 - - - - 0.0000000000000000000000000000000000000001987 163.0
TLS3_k127_5274717_49 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.000000000000000000000000000000000000003862 160.0
TLS3_k127_5274717_5 Dynamin family - - - 9.022e-199 638.0
TLS3_k127_5274717_50 ribosomal subunit interface protein K05808 - - 0.000000000000000000000000000000003685 130.0
TLS3_k127_5274717_51 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000001137 120.0
TLS3_k127_5274717_52 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.00000000000000000004069 102.0
TLS3_k127_5274717_53 domain protein K12516 - - 0.0000002648 63.0
TLS3_k127_5274717_54 FAD linked oxidases, C-terminal domain - - - 0.000009178 50.0
TLS3_k127_5274717_55 alpha amylase catalytic K01182,K05343 - 3.2.1.1,3.2.1.10,5.4.99.16 0.0004026 45.0
TLS3_k127_5274717_6 permease K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 626.0
TLS3_k127_5274717_7 PFAM type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 606.0
TLS3_k127_5274717_8 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit K21393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 596.0
TLS3_k127_5274717_9 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 573.0
TLS3_k127_5286221_0 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 410.0
TLS3_k127_5286221_1 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008746 280.0
TLS3_k127_5286221_2 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000002701 202.0
TLS3_k127_5286221_3 RES - - - 0.00000000000000000000000000000000000000000000000000000005045 203.0
TLS3_k127_5286221_4 Protein of unknown function (DUF2384) - - - 0.000000000000000000000000000086 122.0
TLS3_k127_5286221_5 abc transporter atp-binding protein K06147 - - 0.000000002081 59.0
TLS3_k127_5286221_6 NAD(P)H-binding - - - 0.000003208 59.0
TLS3_k127_5293385_0 Alcohol dehydrogenase GroES-associated - - - 7.272e-224 699.0
TLS3_k127_5293385_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 558.0
TLS3_k127_5293385_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008163 518.0
TLS3_k127_5293385_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 500.0
TLS3_k127_5293385_4 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 385.0
TLS3_k127_5293385_5 abc transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 358.0
TLS3_k127_5293385_6 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 290.0
TLS3_k127_5293385_7 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000002258 214.0
TLS3_k127_5293385_8 Cyclase dehydrase - - - 0.0000000000000000000000000000000000000001469 156.0
TLS3_k127_5293385_9 AI-2E family transporter - - - 0.00003242 49.0
TLS3_k127_5306578_0 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685 - - 2.453e-313 976.0
TLS3_k127_5306578_1 RND efflux system, outer membrane lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 467.0
TLS3_k127_5306578_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 436.0
TLS3_k127_5306578_3 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 305.0
TLS3_k127_5306578_4 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000005287 139.0
TLS3_k127_5306578_5 Type VI secretion system effector, Hcp K11903 - - 0.000000000000187 79.0
TLS3_k127_5318917_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1697.0
TLS3_k127_5318917_1 Glycosyl transferases group 1 - - - 0.0 1131.0
TLS3_k127_5318917_10 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 499.0
TLS3_k127_5318917_11 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 496.0
TLS3_k127_5318917_12 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 487.0
TLS3_k127_5318917_13 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 458.0
TLS3_k127_5318917_14 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009506 456.0
TLS3_k127_5318917_15 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 444.0
TLS3_k127_5318917_16 Domain of unknown function (DUF3329) K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 424.0
TLS3_k127_5318917_17 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 402.0
TLS3_k127_5318917_18 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 395.0
TLS3_k127_5318917_19 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 338.0
TLS3_k127_5318917_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0 1019.0
TLS3_k127_5318917_20 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 307.0
TLS3_k127_5318917_21 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004012 278.0
TLS3_k127_5318917_22 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003831 268.0
TLS3_k127_5318917_23 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000622 252.0
TLS3_k127_5318917_24 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000001349 258.0
TLS3_k127_5318917_25 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002922 250.0
TLS3_k127_5318917_26 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000002293 225.0
TLS3_k127_5318917_27 FR47-like protein - - - 0.000000000000000000000000000000000000000000000000000001254 197.0
TLS3_k127_5318917_28 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000001698 183.0
TLS3_k127_5318917_29 PFAM Rhomboid family protein - - - 0.00000000000000000000000000000000000000000000000005113 198.0
TLS3_k127_5318917_3 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 2.037e-281 902.0
TLS3_k127_5318917_30 Type IV Pilus-assembly protein W K02672 - - 0.0000000000000000000000000000000000000000000000005581 188.0
TLS3_k127_5318917_31 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000000000000000000000002726 174.0
TLS3_k127_5318917_32 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000001083 167.0
TLS3_k127_5318917_33 Pfam Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000002201 166.0
TLS3_k127_5318917_34 MAPEG family - - - 0.0000000000000000000000000000000000001145 145.0
TLS3_k127_5318917_35 competence protein - - - 0.00000000000000000000000000000002118 142.0
TLS3_k127_5318917_36 Prokaryotic N-terminal methylation motif K02671 - - 0.00000000000000000000000000002112 127.0
TLS3_k127_5318917_37 CRS1_YhbY K07574 - - 0.00000000000000000000000003893 111.0
TLS3_k127_5318917_38 Type II transport protein GspH K08084 - - 0.000000000000000000000000114 112.0
TLS3_k127_5318917_39 COG4968 Tfp pilus assembly protein PilE K02655 - - 0.000000000000000000142 96.0
TLS3_k127_5318917_4 Neisseria PilC beta-propeller domain K02674 - - 7.663e-207 679.0
TLS3_k127_5318917_40 Pilus assembly protein PilX - - - 0.000000000000000004195 91.0
TLS3_k127_5318917_41 - - - - 0.0000000000000005774 91.0
TLS3_k127_5318917_42 - - - - 0.000000000000419 75.0
TLS3_k127_5318917_44 - - - - 0.0001209 45.0
TLS3_k127_5318917_5 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 605.0
TLS3_k127_5318917_6 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 567.0
TLS3_k127_5318917_7 Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 553.0
TLS3_k127_5318917_8 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 544.0
TLS3_k127_5318917_9 PD-(D/E)XK nuclease superfamily K01144 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 550.0
TLS3_k127_5333255_0 PFAM peptidase M14, carboxypeptidase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 452.0
TLS3_k127_5333255_1 DNA recombination protein, rmuC K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008566 264.0
TLS3_k127_5333255_2 membrane protein of uknown function UCP014873 - - - 0.000000000000000000000000000000000000000000006338 177.0
TLS3_k127_5333255_3 Acetyltransferase (GNAT) domain K00657 - 2.3.1.57 0.0000000000000000000000000000001014 139.0
TLS3_k127_5333255_4 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000000009439 101.0
TLS3_k127_5333255_5 3' exoribonuclease, RNase T-like - - - 0.00000007019 64.0
TLS3_k127_5356084_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.016e-275 851.0
TLS3_k127_5356084_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 4.002e-206 661.0
TLS3_k127_5356084_10 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000000000129 184.0
TLS3_k127_5356084_11 TonB family K03832 - - 0.00000000000000000002157 98.0
TLS3_k127_5356084_2 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 582.0
TLS3_k127_5356084_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 518.0
TLS3_k127_5356084_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 434.0
TLS3_k127_5356084_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 375.0
TLS3_k127_5356084_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000003214 255.0
TLS3_k127_5356084_7 COG3245 Cytochrome c5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008062 256.0
TLS3_k127_5356084_8 import inner membrane translocase, subunit Tim44 - - - 0.000000000000000000000000000000000000000000000000000000001075 214.0
TLS3_k127_5356084_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000000001909 190.0
TLS3_k127_5373993_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 416.0
TLS3_k127_5373993_1 receptor K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 420.0
TLS3_k127_5373993_2 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008558 383.0
TLS3_k127_5373993_3 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 369.0
TLS3_k127_5373993_4 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000002918 256.0
TLS3_k127_5373993_5 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000004861 233.0
TLS3_k127_5373993_6 Pyridoxamine 5'-phosphate oxidase like - - - 0.0000000000000000000000000000000000000000000000000000000000002302 216.0
TLS3_k127_5373993_7 - - - - 0.0000000000000000001269 94.0
TLS3_k127_5373993_8 - - - - 0.0000000001112 64.0
TLS3_k127_5410566_0 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 390.0
TLS3_k127_5410566_1 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007839 339.0
TLS3_k127_5410566_2 transcriptional Regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 323.0
TLS3_k127_5410566_3 - - - - 0.000000000000000000000000001742 122.0
TLS3_k127_5410566_4 Transcriptional regulator - - - 0.0000000000000000000000001066 110.0
TLS3_k127_5410566_5 Migration and invasion enhancer 1 K07401 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009898,GO:0010941,GO:0016020,GO:0030334,GO:0030335,GO:0031224,GO:0031226,GO:0031235,GO:0031344,GO:0031346,GO:0032879,GO:0040012,GO:0040017,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0044087,GO:0044089,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051270,GO:0051272,GO:0051489,GO:0051491,GO:0060491,GO:0060548,GO:0065007,GO:0071944,GO:0098552,GO:0098562,GO:0120032,GO:0120034,GO:0120035,GO:2000145,GO:2000147 - 0.00004461 47.0
TLS3_k127_5454612_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 3.243e-310 963.0
TLS3_k127_5454612_1 L-carnitine dehydratase bile acid-inducible protein F - - - 5.363e-206 652.0
TLS3_k127_5454612_10 Putative 2OG-Fe(II) oxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 400.0
TLS3_k127_5454612_11 to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 379.0
TLS3_k127_5454612_12 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009123 394.0
TLS3_k127_5454612_13 LrgB-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 336.0
TLS3_k127_5454612_14 Class II aldolase K01628,K22130 - 4.1.1.104,4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 323.0
TLS3_k127_5454612_15 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 303.0
TLS3_k127_5454612_16 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001074 293.0
TLS3_k127_5454612_17 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000003123 218.0
TLS3_k127_5454612_18 Carbohydrate kinase K18478 - 2.7.1.184 0.0000000000000000000000000000000000000000000000000000000005328 213.0
TLS3_k127_5454612_19 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000007597 211.0
TLS3_k127_5454612_2 PFAM type III effector Hrp-dependent outers K21948 - 2.7.1.217 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 567.0
TLS3_k127_5454612_20 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000001142 186.0
TLS3_k127_5454612_21 iron-regulated membrane protein - - - 0.0000000000000000000000000000000000000000000003916 183.0
TLS3_k127_5454612_22 COG3119 Arylsulfatase A and related enzymes - - - 0.000000000000000000000000000000000000000000005492 171.0
TLS3_k127_5454612_23 PFAM sulfatase - - - 0.000000000000000000000000000000004035 133.0
TLS3_k127_5454612_24 LrgA family K06518 - - 0.0000000000000000000000000000001645 138.0
TLS3_k127_5454612_3 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 531.0
TLS3_k127_5454612_4 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 531.0
TLS3_k127_5454612_5 FMN-dependent dehydrogenase K00101 - 1.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 511.0
TLS3_k127_5454612_6 Belongs to the alpha-IPM synthase homocitrate synthase family K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 500.0
TLS3_k127_5454612_7 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009213 460.0
TLS3_k127_5454612_8 Nad-dependent epimerase dehydratase K22025 - 1.1.1.410 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 413.0
TLS3_k127_5454612_9 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 407.0
TLS3_k127_5456622_0 ABC transporter substrate-binding protein PnrA-like K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 486.0
TLS3_k127_5456622_1 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006457 479.0
TLS3_k127_5467865_0 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 5.812e-262 813.0
TLS3_k127_5467865_1 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 587.0
TLS3_k127_5467865_2 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 469.0
TLS3_k127_5467865_3 UPF0761 membrane protein K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 304.0
TLS3_k127_5467865_4 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 291.0
TLS3_k127_5467865_5 Belongs to the WrbA family K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001592 275.0
TLS3_k127_5467865_6 Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000000000000000000000000000000000000004257 219.0
TLS3_k127_5467865_7 Protein of unknown function (DUF962) - - - 0.0000000000000000000000000000000000000000001217 171.0
TLS3_k127_5467865_8 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000008528 120.0
TLS3_k127_5474369_0 carbohydrate binding - - - 0.0 1478.0
TLS3_k127_5474369_1 Belongs to the GPI family K01810 - 5.3.1.9 1.494e-219 696.0
TLS3_k127_5474369_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.041e-215 679.0
TLS3_k127_5474369_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 533.0
TLS3_k127_5474369_4 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 467.0
TLS3_k127_5474369_5 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 296.0
TLS3_k127_5474369_6 SMART Extracellular solute-binding protein, family 3 K02030 - - 0.000000000000000000000000000000000004319 138.0
TLS3_k127_5474369_7 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03321 - - 0.0000000000000000000000000002069 119.0
TLS3_k127_5477073_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 477.0
TLS3_k127_5477073_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 454.0
TLS3_k127_5477073_2 Belongs to the ABC transporter superfamily K02031,K16202 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 420.0
TLS3_k127_5477073_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003057 254.0
TLS3_k127_5484729_0 Major facilitator superfamily MFS_1 K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 584.0
TLS3_k127_5484729_1 Transcriptional regulator K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 304.0
TLS3_k127_5484729_2 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362 - 1.7.1.15 0.000000000000002652 83.0
TLS3_k127_5515430_0 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005427 308.0
TLS3_k127_5515430_1 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009727 251.0
TLS3_k127_5515430_2 NlpB/DapX lipoprotein K07287 - - 0.0000000000000000136 84.0
TLS3_k127_5515430_3 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000005109 55.0
TLS3_k127_5544366_0 RecA-superfamily ATPases implicated in signal transduction K08482 - - 6.234e-215 678.0
TLS3_k127_5544366_1 His Kinase A (phospho-acceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 451.0
TLS3_k127_5544366_2 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 327.0
TLS3_k127_5544366_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000002866 221.0
TLS3_k127_5544366_5 Histidine kinase - - - 0.000686 44.0
TLS3_k127_5560218_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1234.0
TLS3_k127_5560218_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 9.411e-253 788.0
TLS3_k127_5560218_10 Protein of unknown function (DUF1223) - - - 0.00000000000000000000000000000000000000000000000000004989 196.0
TLS3_k127_5560218_11 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.00000000000000000000000000000000000000000000000002377 187.0
TLS3_k127_5560218_12 Small multidrug resistance protein K11741 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000003233 132.0
TLS3_k127_5560218_13 - - - - 0.000000000000000000000004292 100.0
TLS3_k127_5560218_15 - - - - 0.00007738 50.0
TLS3_k127_5560218_17 Protein of unknown function (DUF2891) - - - 0.0002839 44.0
TLS3_k127_5560218_2 Penicillin amidase K01434 - 3.5.1.11 2.203e-241 771.0
TLS3_k127_5560218_3 Extracellular solute-binding protein, family 5 middle family protein K02035 - - 1.828e-223 705.0
TLS3_k127_5560218_4 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 552.0
TLS3_k127_5560218_5 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 527.0
TLS3_k127_5560218_6 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 497.0
TLS3_k127_5560218_7 ATPases associated with a variety of cellular activities K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 471.0
TLS3_k127_5560218_8 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 455.0
TLS3_k127_5560218_9 impB/mucB/samB family K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 368.0
TLS3_k127_5587703_0 belongs to the nudix hydrolase family - - - 0.00000000000000000000000000000000000000000000000008845 183.0
TLS3_k127_5587703_1 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000003631 169.0
TLS3_k127_5587703_2 Ankyrin repeats (3 copies) - - - 0.00000000000108 78.0
TLS3_k127_5641887_0 ammonium transporter K03320 - - 5.49e-214 677.0
TLS3_k127_5641887_1 Glutamate-cysteine ligase K01919 - 6.3.2.2 2.061e-202 638.0
TLS3_k127_5641887_10 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 345.0
TLS3_k127_5641887_11 proteasome-type protease K07395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 316.0
TLS3_k127_5641887_12 PFAM Uracil-DNA glycosylase superfamily K10800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 306.0
TLS3_k127_5641887_13 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009472 295.0
TLS3_k127_5641887_14 PFAM N-formylglutamate amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003973 273.0
TLS3_k127_5641887_15 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000005094 236.0
TLS3_k127_5641887_16 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000007655 234.0
TLS3_k127_5641887_17 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000000000006667 216.0
TLS3_k127_5641887_18 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000000000000000000000000003222 206.0
TLS3_k127_5641887_19 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000001278 217.0
TLS3_k127_5641887_2 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 592.0
TLS3_k127_5641887_20 Lysine exporter protein LysE K11250 - - 0.00000000000000000000000000000000000000000000000000009776 194.0
TLS3_k127_5641887_21 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000001094 196.0
TLS3_k127_5641887_22 - - - - 0.000000000000000000000000000000000000000000000000000176 193.0
TLS3_k127_5641887_23 endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000005527 164.0
TLS3_k127_5641887_24 pts system fructose subfamily IIa component K02821 - 2.7.1.194 0.000000000000000000000000000000000325 137.0
TLS3_k127_5641887_25 phosphocarrier protein Hpr K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000057 108.0
TLS3_k127_5641887_26 Membrane fusogenic activity K09806 - - 0.00000000000000000004505 91.0
TLS3_k127_5641887_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 578.0
TLS3_k127_5641887_4 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 556.0
TLS3_k127_5641887_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 431.0
TLS3_k127_5641887_6 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 378.0
TLS3_k127_5641887_7 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 359.0
TLS3_k127_5641887_8 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 351.0
TLS3_k127_5641887_9 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 349.0
TLS3_k127_5661475_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 456.0
TLS3_k127_5661475_1 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 340.0
TLS3_k127_5661475_10 PFAM LemA K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000001837 247.0
TLS3_k127_5661475_11 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000001402 240.0
TLS3_k127_5661475_12 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K04756 - - 0.000000000000000000000000000000000000000000000000000000000000000001516 231.0
TLS3_k127_5661475_13 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000002949 232.0
TLS3_k127_5661475_14 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.0000000000000000000000000000000000000000000000000000000000003131 220.0
TLS3_k127_5661475_15 Redoxin - - - 0.00000000000000000000000000000000000000000000000000003951 192.0
TLS3_k127_5661475_16 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000005398 197.0
TLS3_k127_5661475_17 TPM domain - - - 0.0000000000000000000000000000000000000000000003353 171.0
TLS3_k127_5661475_18 Domain of unknown function (DUF4266) - - - 0.00000000000000001128 86.0
TLS3_k127_5661475_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 329.0
TLS3_k127_5661475_3 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 330.0
TLS3_k127_5661475_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 321.0
TLS3_k127_5661475_5 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 300.0
TLS3_k127_5661475_6 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 291.0
TLS3_k127_5661475_7 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000801 310.0
TLS3_k127_5661475_8 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000002648 266.0
TLS3_k127_5661475_9 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000006108 253.0
TLS3_k127_5761373_0 DNA ligase K01971 - 6.5.1.1 0.0 1229.0
TLS3_k127_5761373_1 Chromate transporter K07240 - - 1.99e-220 689.0
TLS3_k127_5761373_10 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 439.0
TLS3_k127_5761373_11 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 419.0
TLS3_k127_5761373_12 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 408.0
TLS3_k127_5761373_13 DnaJ C terminal domain K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008551 394.0
TLS3_k127_5761373_14 Binding-protein-dependent transport system inner membrane component K02026,K17323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 378.0
TLS3_k127_5761373_15 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 395.0
TLS3_k127_5761373_16 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 342.0
TLS3_k127_5761373_17 ornithine cyclodeaminase activity K01750,K18258,K19244 - 1.4.1.1,1.5.1.25,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 336.0
TLS3_k127_5761373_18 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 299.0
TLS3_k127_5761373_19 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003363 271.0
TLS3_k127_5761373_2 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 560.0
TLS3_k127_5761373_20 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003037 277.0
TLS3_k127_5761373_21 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000004057 237.0
TLS3_k127_5761373_22 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005264 235.0
TLS3_k127_5761373_23 - - - - 0.0000000000000000000000000000000000000000000000000000000004805 209.0
TLS3_k127_5761373_24 LemA family - - - 0.000000000000000000000000000000000000000000003922 169.0
TLS3_k127_5761373_25 - - - - 0.0000000000000000000000000000000000002964 143.0
TLS3_k127_5761373_26 MerR HTH family regulatory protein K18997 - - 0.000000000000000000002415 96.0
TLS3_k127_5761373_27 Protein of unknown function (DUF1573) - - - 0.0001261 53.0
TLS3_k127_5761373_3 Methyltransferase K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 507.0
TLS3_k127_5761373_4 Zinc-dependent metalloprotease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 498.0
TLS3_k127_5761373_5 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 474.0
TLS3_k127_5761373_6 TOBE domain K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 466.0
TLS3_k127_5761373_7 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 459.0
TLS3_k127_5761373_8 Protein of unknown function (DUF1615) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007595 457.0
TLS3_k127_5761373_9 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 439.0
TLS3_k127_5776785_0 Pilus retraction K02669,K12203 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 374.0
TLS3_k127_5776785_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 289.0
TLS3_k127_5776785_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000316 44.0
TLS3_k127_58105_0 intracellular signal transduction K01768 - 4.6.1.1 9.05e-304 979.0
TLS3_k127_58105_1 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008948 377.0
TLS3_k127_58105_2 Dyp-type peroxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003845 295.0
TLS3_k127_58105_3 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000004262 253.0
TLS3_k127_58105_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000005945 213.0
TLS3_k127_58105_5 PFAM Thiamine pyrophosphate K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000003127 183.0
TLS3_k127_58105_6 Lecithin retinol acyltransferase - - - 0.0000000000000000000000000000000000000000005925 162.0
TLS3_k127_5841585_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 1.441e-248 774.0
TLS3_k127_5841585_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 451.0
TLS3_k127_5841585_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000005144 152.0
TLS3_k127_5864351_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 3.108e-210 664.0
TLS3_k127_5864351_1 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.00000000000000000000000000009311 117.0
TLS3_k127_5871220_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1463.0
TLS3_k127_5871220_1 Methylmalonyl-CoA mutase K01848 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 5.4.99.2 8.17e-232 729.0
TLS3_k127_5871220_10 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000001051 219.0
TLS3_k127_5871220_11 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000000000000000000000000008865 204.0
TLS3_k127_5871220_12 Prolyl oligopeptidase family K06889 - - 0.000000000000000000000000000000000000000000000000000000001872 212.0
TLS3_k127_5871220_13 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000009907 190.0
TLS3_k127_5871220_14 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000001186 183.0
TLS3_k127_5871220_15 B12 binding domain K01849 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0036094,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901363,GO:1901564 5.4.99.2 0.00000000000000000000000000000000000000000000001316 175.0
TLS3_k127_5871220_16 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000002212 164.0
TLS3_k127_5871220_17 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000000000000000000000001405 143.0
TLS3_k127_5871220_18 PFAM glutathione-dependent formaldehyde-activating GFA - - - 0.00000000000000000000000000000002034 131.0
TLS3_k127_5871220_2 L-serine dehydratase K01752 - 4.3.1.17 3.762e-217 681.0
TLS3_k127_5871220_3 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 575.0
TLS3_k127_5871220_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 549.0
TLS3_k127_5871220_5 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 482.0
TLS3_k127_5871220_6 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 409.0
TLS3_k127_5871220_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 352.0
TLS3_k127_5871220_8 formamidopyrimidine-DNA glycosylase K05522 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 334.0
TLS3_k127_5871220_9 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006128 283.0
TLS3_k127_5902833_0 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000003503 220.0
TLS3_k127_5902833_1 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000000000000000000000008722 124.0
TLS3_k127_5926760_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 573.0
TLS3_k127_5926760_1 TIGRFAM TRAP dicarboxylate transporter, DctP subunit K21395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 471.0
TLS3_k127_5926760_10 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000255 57.0
TLS3_k127_5926760_11 Transcriptional regulator - - - 0.00007521 51.0
TLS3_k127_5926760_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009199 283.0
TLS3_k127_5926760_3 MOSC N-terminal beta barrel domain K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001989 271.0
TLS3_k127_5926760_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002506 262.0
TLS3_k127_5926760_5 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000004659 195.0
TLS3_k127_5926760_6 Protein of unknown function (DUF418) K07148 - - 0.0000000000000000000000000000000000000000861 166.0
TLS3_k127_5926760_7 PFAM Acetyltransferase (GNAT) family K00657 - 2.3.1.57 0.00000000000000000000000000003485 123.0
TLS3_k127_5926760_8 - - - - 0.000000000009969 71.0
TLS3_k127_5926760_9 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000001279 62.0
TLS3_k127_5940631_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.378e-248 774.0
TLS3_k127_5940631_1 Glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 1.797e-213 677.0
TLS3_k127_5940631_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008065 571.0
TLS3_k127_5940631_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 549.0
TLS3_k127_5940631_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009388 548.0
TLS3_k127_5940631_5 LysM domain K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 435.0
TLS3_k127_5940631_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 355.0
TLS3_k127_5940631_7 Zn-dependent protease with chaperone function K07387 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 302.0
TLS3_k127_5940631_8 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 299.0
TLS3_k127_5940631_9 Dioxygenase - - - 0.00000000000000000000000000000000000001398 163.0
TLS3_k127_5986476_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 8.421e-318 985.0
TLS3_k127_5986476_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 7.769e-316 977.0
TLS3_k127_5986476_10 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000995 487.0
TLS3_k127_5986476_11 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 430.0
TLS3_k127_5986476_12 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 375.0
TLS3_k127_5986476_13 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 361.0
TLS3_k127_5986476_14 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 347.0
TLS3_k127_5986476_15 dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 351.0
TLS3_k127_5986476_16 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 355.0
TLS3_k127_5986476_17 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 335.0
TLS3_k127_5986476_18 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 329.0
TLS3_k127_5986476_19 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 318.0
TLS3_k127_5986476_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 4.668e-314 974.0
TLS3_k127_5986476_20 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 314.0
TLS3_k127_5986476_21 Divalent heavy-metal cations transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001546 283.0
TLS3_k127_5986476_22 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001362 276.0
TLS3_k127_5986476_23 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000001439 265.0
TLS3_k127_5986476_24 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000002921 242.0
TLS3_k127_5986476_25 Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000000000000000000000000000008099 228.0
TLS3_k127_5986476_26 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000003063 225.0
TLS3_k127_5986476_27 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000001212 212.0
TLS3_k127_5986476_28 N-acetyltransferase K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000004422 194.0
TLS3_k127_5986476_29 Protein of unknown function (DUF962) - - - 0.00000000000000000000000000000000000000000000007296 174.0
TLS3_k127_5986476_3 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.736e-289 903.0
TLS3_k127_5986476_30 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000000000000007989 169.0
TLS3_k127_5986476_31 Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000001559 152.0
TLS3_k127_5986476_32 Cold shock protein K03704 - - 0.00000000000000000000000000000000006036 134.0
TLS3_k127_5986476_33 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000004964 102.0
TLS3_k127_5986476_34 Belongs to the UPF0434 family K09791 - - 0.0000000000000000001263 90.0
TLS3_k127_5986476_35 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000001384 87.0
TLS3_k127_5986476_4 Belongs to the ClpA ClpB family K03694 - - 6.213e-252 786.0
TLS3_k127_5986476_5 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 1.239e-247 769.0
TLS3_k127_5986476_6 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 8.171e-233 724.0
TLS3_k127_5986476_7 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 7.606e-220 700.0
TLS3_k127_5986476_8 ABC-type dipeptide transport system, periplasmic component K02035 - - 9.954e-206 653.0
TLS3_k127_5986476_9 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 560.0
TLS3_k127_5990421_0 o-acetylhomoserine K01740 - 2.5.1.49 3.599e-216 677.0
TLS3_k127_5990421_1 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005894 425.0
TLS3_k127_5990421_2 FAD dependent oxidoreductase K06955 - - 0.00000000000000000000000000000000000000000000000000000000000000002402 236.0
TLS3_k127_5990421_3 CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000007115 214.0
TLS3_k127_5990421_4 ABC-type dipeptide transport system periplasmic component K02035 - - 0.0000000000000000000000000000000000000000000001146 170.0
TLS3_k127_5990421_5 Glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 0.0000000000002956 71.0
TLS3_k127_6024127_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1298.0
TLS3_k127_6024127_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.632e-211 668.0
TLS3_k127_6024127_10 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 414.0
TLS3_k127_6024127_11 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 395.0
TLS3_k127_6024127_12 ATPase (AAA superfamily) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 350.0
TLS3_k127_6024127_13 Type IV leader peptidase family K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 338.0
TLS3_k127_6024127_14 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 329.0
TLS3_k127_6024127_15 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 315.0
TLS3_k127_6024127_16 Peptidase family M23 K08259 - 3.4.24.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 308.0
TLS3_k127_6024127_17 Thiamine monophosphate synthase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 295.0
TLS3_k127_6024127_18 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000407 198.0
TLS3_k127_6024127_19 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.0000000000000000000000000000000000000000007824 168.0
TLS3_k127_6024127_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 8.701e-207 653.0
TLS3_k127_6024127_20 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000005467 83.0
TLS3_k127_6024127_21 COG1459 Type II secretory pathway, component PulF K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776 - 0.00000006489 53.0
TLS3_k127_6024127_22 Protein of unknown function (DUF721) - - - 0.0002332 50.0
TLS3_k127_6024127_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 586.0
TLS3_k127_6024127_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 559.0
TLS3_k127_6024127_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 527.0
TLS3_k127_6024127_6 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 517.0
TLS3_k127_6024127_7 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005412 513.0
TLS3_k127_6024127_8 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 512.0
TLS3_k127_6024127_9 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 413.0
TLS3_k127_6040095_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 487.0
TLS3_k127_6040095_1 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000002365 156.0
TLS3_k127_6040095_2 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000001121 98.0
TLS3_k127_6040095_3 3-beta hydroxysteroid dehydrogenase isomerase - - - 0.000000000008116 70.0
TLS3_k127_6049508_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 530.0
TLS3_k127_6049508_1 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 362.0
TLS3_k127_6049508_2 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003887 238.0
TLS3_k127_6049508_3 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000000000000000002578 162.0
TLS3_k127_6049508_4 Nuclease (SNase domain protein) - - - 0.000000000000000000000000000000104 126.0
TLS3_k127_6049508_5 transcriptional regulator - - - 0.00000000000000000000000000009324 124.0
TLS3_k127_6079967_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2448.0
TLS3_k127_6079967_1 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 463.0
TLS3_k127_6079967_2 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 369.0
TLS3_k127_6079967_3 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001405 266.0
TLS3_k127_6082268_0 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 302.0
TLS3_k127_6082268_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000003439 206.0
TLS3_k127_6082268_2 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000009659 159.0
TLS3_k127_6082268_3 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - 0.000000000000000005968 85.0
TLS3_k127_6087090_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1229.0
TLS3_k127_6087090_1 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 530.0
TLS3_k127_6087090_10 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000000000000000000004831 194.0
TLS3_k127_6087090_11 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000004635 164.0
TLS3_k127_6087090_12 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000002141 154.0
TLS3_k127_6087090_13 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000004251 144.0
TLS3_k127_6087090_14 Bacterial regulatory proteins, tetR family K16137 - - 0.00000000000000000000000000000001787 134.0
TLS3_k127_6087090_15 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000001936 108.0
TLS3_k127_6087090_16 - - - - 0.0000000000000006609 87.0
TLS3_k127_6087090_17 Chorismate mutase K00014,K00891,K04092,K04516 - 1.1.1.25,2.7.1.71,5.4.99.5 0.00002367 46.0
TLS3_k127_6087090_2 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009883 436.0
TLS3_k127_6087090_3 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 363.0
TLS3_k127_6087090_4 LysR substrate binding domain K13634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 366.0
TLS3_k127_6087090_5 Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 305.0
TLS3_k127_6087090_6 esterase K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 295.0
TLS3_k127_6087090_7 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005112 291.0
TLS3_k127_6087090_8 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000005773 214.0
TLS3_k127_6087090_9 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000005922 212.0
TLS3_k127_6147239_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 471.0
TLS3_k127_6147239_1 Heavy-metal-associated domain K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000002562 200.0
TLS3_k127_6147239_2 PFAM Sterol-binding domain protein K03690 - - 0.000000000000000000000000000000004129 135.0
TLS3_k127_6152574_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1401.0
TLS3_k127_6152574_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1124.0
TLS3_k127_6152574_10 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 407.0
TLS3_k127_6152574_11 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 376.0
TLS3_k127_6152574_12 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 373.0
TLS3_k127_6152574_13 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 357.0
TLS3_k127_6152574_14 helix_turn_helix, Lux Regulon K13041 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 290.0
TLS3_k127_6152574_15 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 285.0
TLS3_k127_6152574_16 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001083 263.0
TLS3_k127_6152574_17 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000001323 227.0
TLS3_k127_6152574_18 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000231 201.0
TLS3_k127_6152574_19 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000001675 194.0
TLS3_k127_6152574_2 Peptidase family M3 K01414 - 3.4.24.70 1.235e-281 880.0
TLS3_k127_6152574_20 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000000000003838 174.0
TLS3_k127_6152574_21 Protein of unknown function (DUF2459) - - - 0.00000000000000000000000000000000000000000001375 171.0
TLS3_k127_6152574_22 - - - - 0.0000000000000000000000000000000000001206 149.0
TLS3_k127_6152574_23 PFAM Glutaredoxin - - - 0.000000000000000000000000000000002227 136.0
TLS3_k127_6152574_24 PFAM Glutaredoxin - - - 0.00000000000000000000000000000006457 133.0
TLS3_k127_6152574_25 Histidine kinase - - - 0.000000000000000009618 96.0
TLS3_k127_6152574_26 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000002035 90.0
TLS3_k127_6152574_27 COG3617 Prophage antirepressor - - - 0.0009976 49.0
TLS3_k127_6152574_3 highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 1.835e-259 805.0
TLS3_k127_6152574_4 pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 9.897e-238 752.0
TLS3_k127_6152574_5 Sigma-54 interaction domain K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 2.407e-221 696.0
TLS3_k127_6152574_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 2.254e-200 638.0
TLS3_k127_6152574_7 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 591.0
TLS3_k127_6152574_8 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 592.0
TLS3_k127_6152574_9 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 565.0
TLS3_k127_6156130_0 CBS domain containing protein K03699 - - 4.842e-219 686.0
TLS3_k127_6156130_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000002195 65.0
TLS3_k127_6156130_2 - - - - 0.00000000002726 66.0
TLS3_k127_6166894_0 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 361.0
TLS3_k127_6166894_1 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 363.0
TLS3_k127_6166894_2 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 359.0
TLS3_k127_6166894_3 Glutathionylspermidine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 344.0
TLS3_k127_6166894_4 iron ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002584 277.0
TLS3_k127_6166894_5 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000000000000000002175 200.0
TLS3_k127_6166894_6 COG1982 Arginine lysine ornithine decarboxylases K01584 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000008313 190.0
TLS3_k127_6166894_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000007683 171.0
TLS3_k127_6166894_8 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000786 162.0
TLS3_k127_6166894_9 Domain of Unknown Function (DUF350) K08989 - - 0.0000000000000000000000000000008914 125.0
TLS3_k127_6190882_0 RNA polymerase K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 285.0
TLS3_k127_6190882_1 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K13896,K15583 - - 0.0000000000000000000000000000000000000000000000000008142 185.0
TLS3_k127_6190882_2 - - - - 0.0000000000000000000000000000000000005578 148.0
TLS3_k127_6190882_3 Protein of unknown function (DUF3106) - - - 0.000000000000000000000000006027 116.0
TLS3_k127_6190882_4 PFAM RDD domain containing protein - - - 0.000000000000000000000000008354 116.0
TLS3_k127_6190882_6 Catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive K01652 - 2.2.1.6 0.0000000000000000001653 89.0
TLS3_k127_6190882_7 Protein of unknown function (DUF3619) - - - 0.00000000000299 74.0
TLS3_k127_6198435_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.328e-247 771.0
TLS3_k127_6198435_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 8.872e-226 706.0
TLS3_k127_6198435_10 Sporulation related domain K03749 - - 0.000000000000000000002754 102.0
TLS3_k127_6198435_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 568.0
TLS3_k127_6198435_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 531.0
TLS3_k127_6198435_4 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 501.0
TLS3_k127_6198435_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 477.0
TLS3_k127_6198435_6 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 320.0
TLS3_k127_6198435_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 302.0
TLS3_k127_6198435_8 Rrf2 family transcriptional regulator, iron-sulfur cluster assembly K13643 - - 0.0000000000000000000000000000000000000000000000000000000000000003534 223.0
TLS3_k127_6198435_9 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000002746 224.0
TLS3_k127_620190_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 2.763e-234 734.0
TLS3_k127_620190_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 373.0
TLS3_k127_620190_2 Belongs to the transcriptional regulatory Fis family K03557 - - 0.0000000000000000000002384 100.0
TLS3_k127_6205804_0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 5.13e-221 702.0
TLS3_k127_6205804_1 Transmembrane secretion effector - - - 5.642e-196 632.0
TLS3_k127_6205804_2 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 609.0
TLS3_k127_6205804_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 425.0
TLS3_k127_6205804_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009666 413.0
TLS3_k127_6205804_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 395.0
TLS3_k127_6205804_6 Aminoacyl-tRNA editing domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002078 230.0
TLS3_k127_6205804_7 glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000001415 232.0
TLS3_k127_6205804_8 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000008635 183.0
TLS3_k127_6205804_9 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000007505 119.0
TLS3_k127_6212129_0 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000006681 236.0
TLS3_k127_6212129_1 - - - - 0.0000000000000000000000000000000000000000002029 173.0
TLS3_k127_6221657_0 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 546.0
TLS3_k127_6221657_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 519.0
TLS3_k127_6221657_2 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 499.0
TLS3_k127_6221657_3 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 445.0
TLS3_k127_6251912_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 5.888e-240 749.0
TLS3_k127_6251912_1 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 554.0
TLS3_k127_6251912_2 PFAM CHRD domain containing protein - - - 0.000000000000000000000000000000000000000000006392 167.0
TLS3_k127_6263397_0 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 7.466e-213 676.0
TLS3_k127_6263397_1 Phage tail sheath C-terminal domain K06907 - - 0.00000000000000000000000000000000000000000000000000002275 199.0
TLS3_k127_6263397_2 Acetyltransferase (GNAT) family - - - 0.000134 47.0
TLS3_k127_6269779_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.924e-298 920.0
TLS3_k127_6269779_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.476e-265 822.0
TLS3_k127_6269779_10 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 467.0
TLS3_k127_6269779_11 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 439.0
TLS3_k127_6269779_12 RNA polymerase sigma factor RpoH K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 423.0
TLS3_k127_6269779_13 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006728 400.0
TLS3_k127_6269779_14 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 404.0
TLS3_k127_6269779_15 cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 395.0
TLS3_k127_6269779_16 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 374.0
TLS3_k127_6269779_17 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007338 376.0
TLS3_k127_6269779_18 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 346.0
TLS3_k127_6269779_19 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 335.0
TLS3_k127_6269779_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.398e-253 801.0
TLS3_k127_6269779_20 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 321.0
TLS3_k127_6269779_21 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 306.0
TLS3_k127_6269779_22 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 298.0
TLS3_k127_6269779_23 acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000903 267.0
TLS3_k127_6269779_24 PFAM regulatory protein TetR K05501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001373 259.0
TLS3_k127_6269779_25 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002148 252.0
TLS3_k127_6269779_26 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000002403 255.0
TLS3_k127_6269779_27 response to antibiotic - - - 0.00000000000000000000000000000000000000000000000000000000000000001255 243.0
TLS3_k127_6269779_28 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000000006983 226.0
TLS3_k127_6269779_29 cytochrome C oxidase K02258 - - 0.0000000000000000000000000000000000000000000000000000000000000001142 226.0
TLS3_k127_6269779_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 8.426e-227 706.0
TLS3_k127_6269779_30 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000000000001344 228.0
TLS3_k127_6269779_31 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000002004 221.0
TLS3_k127_6269779_32 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000000000000000000000886 209.0
TLS3_k127_6269779_33 Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000000000000000001165 200.0
TLS3_k127_6269779_34 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000000000000001012 197.0
TLS3_k127_6269779_35 signal sequence binding - - - 0.000000000000000000000000000000000000000000000000000006798 197.0
TLS3_k127_6269779_36 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000003421 175.0
TLS3_k127_6269779_37 phosphohistidine phosphatase, SixA K08296 - - 0.00000000000000000000000000000000000000000000003017 175.0
TLS3_k127_6269779_38 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000008072 163.0
TLS3_k127_6269779_39 SURF1-like protein K14998 - - 0.000000000000000000000000000000000000000366 159.0
TLS3_k127_6269779_4 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.159e-210 664.0
TLS3_k127_6269779_40 Pfam:DUF461 K09796 - - 0.00000000000000000000000000000000000003322 147.0
TLS3_k127_6269779_41 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000000000022 138.0
TLS3_k127_6269779_42 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000000000000001884 135.0
TLS3_k127_6269779_43 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000005125 129.0
TLS3_k127_6269779_44 Protein of unknown function (DUF2909) - - - 0.00000000000000000003145 91.0
TLS3_k127_6269779_45 Integral membrane protein (DUF2244) - - - 0.0000000000000001687 88.0
TLS3_k127_6269779_46 Protein of unknown function (DUF2970) - - - 0.000000000002947 69.0
TLS3_k127_6269779_47 - - - - 0.000001165 58.0
TLS3_k127_6269779_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 569.0
TLS3_k127_6269779_6 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 567.0
TLS3_k127_6269779_7 Cobalamin biosynthesis protein CobW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 499.0
TLS3_k127_6269779_8 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 471.0
TLS3_k127_6269779_9 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 472.0
TLS3_k127_6270455_0 PFAM FAD dependent oxidoreductase K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000001192 255.0
TLS3_k127_6270455_1 Histidine kinase K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005067 249.0
TLS3_k127_6270455_2 Domain of unknown function (DUF4198) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001788 246.0
TLS3_k127_6270455_3 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.00000000000000000000000000000000001457 141.0
TLS3_k127_6274115_0 Prolyl oligopeptidase K01322 - 3.4.21.26 3.006e-309 966.0
TLS3_k127_6274115_1 Esterase PHB depolymerase - - - 0.000000000000000000000000000000000001472 140.0
TLS3_k127_6274115_2 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000007512 55.0
TLS3_k127_6280232_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1628.0
TLS3_k127_6280232_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1217.0
TLS3_k127_6280232_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001632 267.0
TLS3_k127_6280232_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000458 232.0
TLS3_k127_6280232_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000209 87.0
TLS3_k127_6281374_0 oxidoreductase K04090 - 1.2.7.8 0.0 1612.0
TLS3_k127_6281374_1 Belongs to the IlvD Edd family K13875 - 4.2.1.25 2.145e-312 965.0
TLS3_k127_6281374_10 type II secretion system protein E K02454,K02652 - - 1.112e-209 661.0
TLS3_k127_6281374_11 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 1.876e-199 626.0
TLS3_k127_6281374_12 general secretion pathway protein D K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 624.0
TLS3_k127_6281374_13 Phospholipase D Transphosphatidylase K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 552.0
TLS3_k127_6281374_14 fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 543.0
TLS3_k127_6281374_15 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 507.0
TLS3_k127_6281374_16 ABC-type sugar K02025,K10237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 502.0
TLS3_k127_6281374_17 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008073 531.0
TLS3_k127_6281374_18 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 493.0
TLS3_k127_6281374_19 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 495.0
TLS3_k127_6281374_2 Peptidase family M3 K01284 - 3.4.15.5 4.374e-258 812.0
TLS3_k127_6281374_20 peptidase family M13 K07386 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 501.0
TLS3_k127_6281374_21 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 471.0
TLS3_k127_6281374_22 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 462.0
TLS3_k127_6281374_23 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 462.0
TLS3_k127_6281374_24 General secretion pathway protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 436.0
TLS3_k127_6281374_25 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 428.0
TLS3_k127_6281374_26 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 427.0
TLS3_k127_6281374_27 PFAM aromatic amino acid K00500 - 1.14.16.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 415.0
TLS3_k127_6281374_28 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 450.0
TLS3_k127_6281374_29 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 413.0
TLS3_k127_6281374_3 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K16846 - 4.2.1.7,4.4.1.24 1.403e-231 727.0
TLS3_k127_6281374_30 Belongs to the LDH2 MDH2 oxidoreductase family K00016 - 1.1.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 413.0
TLS3_k127_6281374_31 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01760 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 406.0
TLS3_k127_6281374_32 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 361.0
TLS3_k127_6281374_33 PFAM L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 366.0
TLS3_k127_6281374_34 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 343.0
TLS3_k127_6281374_35 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 347.0
TLS3_k127_6281374_36 KR domain K21883 - 1.1.1.401 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 327.0
TLS3_k127_6281374_37 Converts GTP to 7,8-dihydroneopterin triphosphate K01495,K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 327.0
TLS3_k127_6281374_38 Pfam Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 312.0
TLS3_k127_6281374_39 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 306.0
TLS3_k127_6281374_4 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 1.141e-229 719.0
TLS3_k127_6281374_40 KR domain K00076 - 1.1.1.159 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 298.0
TLS3_k127_6281374_41 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 297.0
TLS3_k127_6281374_42 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004717 281.0
TLS3_k127_6281374_43 Glutathione peroxidase K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000001738 241.0
TLS3_k127_6281374_44 Regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000177 223.0
TLS3_k127_6281374_45 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000002138 211.0
TLS3_k127_6281374_46 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000000000000001249 201.0
TLS3_k127_6281374_47 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000004605 198.0
TLS3_k127_6281374_48 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000000004422 203.0
TLS3_k127_6281374_49 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.000000000000000000000000000000000000000000000000002054 193.0
TLS3_k127_6281374_5 DNA helicase K03654 - 3.6.4.12 1.889e-225 714.0
TLS3_k127_6281374_50 membrane - - - 0.0000000000000000000000000000000000000000000000008131 179.0
TLS3_k127_6281374_51 Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000000000002735 181.0
TLS3_k127_6281374_52 General Secretory Pathway K02463 - - 0.0000000000000000000000000000000000005279 151.0
TLS3_k127_6281374_53 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000005654 149.0
TLS3_k127_6281374_54 Sporulation related domain - - - 0.000000000000000000000000000000000008137 142.0
TLS3_k127_6281374_55 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000005069 141.0
TLS3_k127_6281374_56 protein conserved in bacteria - - - 0.00000000000000000000000009384 119.0
TLS3_k127_6281374_57 General secretion pathway protein I K02458 - - 0.000000000000000000000006865 105.0
TLS3_k127_6281374_58 - - - - 0.000000000000000000003828 102.0
TLS3_k127_6281374_59 General secretion pathway protein L K02461 - - 0.000000000000000000008586 106.0
TLS3_k127_6281374_6 Arginyl-tRNA synthetase K01887 - 6.1.1.19 2.221e-224 709.0
TLS3_k127_6281374_60 general secretion pathway protein K02457 - - 0.00000000000000000005682 96.0
TLS3_k127_6281374_61 General secretion pathway K02462 - - 0.0000000000000000002729 94.0
TLS3_k127_6281374_62 general secretion pathway protein K02459 - - 0.0000000000000000007868 95.0
TLS3_k127_6281374_63 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000002258 85.0
TLS3_k127_6281374_64 Protein of unknown function (DUF3108) - - - 0.0000000000000002205 91.0
TLS3_k127_6281374_65 membrane - - - 0.00000000000006637 79.0
TLS3_k127_6281374_66 EF-hand domain pair - - - 0.00000000549 62.0
TLS3_k127_6281374_67 general secretion pathway protein K02452 - - 0.00000002017 64.0
TLS3_k127_6281374_68 - - - - 0.000104 48.0
TLS3_k127_6281374_7 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 8.595e-218 692.0
TLS3_k127_6281374_8 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 1.383e-215 674.0
TLS3_k127_6281374_9 Bacterial extracellular solute-binding protein K02027 - - 3.302e-212 666.0
TLS3_k127_6293365_0 Belongs to the DapB family K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 362.0
TLS3_k127_6293365_1 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000000002495 158.0
TLS3_k127_6293365_2 - - - - 0.000000000000000000000000002168 112.0
TLS3_k127_6310821_0 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 437.0
TLS3_k127_6310821_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 313.0
TLS3_k127_6310821_10 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000006465 127.0
TLS3_k127_6310821_11 Putative prokaryotic signal transducing protein - - - 0.000000000000000000000000001372 116.0
TLS3_k127_6310821_12 TM2 domain - - - 0.000000000000000003273 92.0
TLS3_k127_6310821_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 298.0
TLS3_k127_6310821_3 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000111 265.0
TLS3_k127_6310821_4 Nudix hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001343 251.0
TLS3_k127_6310821_5 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000000004093 206.0
TLS3_k127_6310821_6 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000001522 203.0
TLS3_k127_6310821_7 PFAM Transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000316 136.0
TLS3_k127_6310821_8 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000000004722 136.0
TLS3_k127_6310821_9 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.0000000000000000000000000000008053 122.0
TLS3_k127_6326847_0 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 1.383e-236 740.0
TLS3_k127_6326847_1 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 309.0
TLS3_k127_6326847_2 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000004517 231.0
TLS3_k127_6326847_3 Las17-binding protein actin regulator - - - 0.000000000000000000000000295 111.0
TLS3_k127_6326847_4 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000001335 64.0
TLS3_k127_6327046_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 7.097e-294 940.0
TLS3_k127_6327046_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 1.989e-258 816.0
TLS3_k127_6327046_10 Protein of unknown function (DUF3299) K09950 - - 0.000000000000000000000000000000000004884 143.0
TLS3_k127_6327046_11 Putative member of DMT superfamily (DUF486) K09922 - - 0.000000000000000000000000000000000006685 143.0
TLS3_k127_6327046_12 COG2513 PEP phosphonomutase and related enzymes - - - 0.00000000000000138 78.0
TLS3_k127_6327046_13 - - - - 0.0000000000006809 78.0
TLS3_k127_6327046_2 Oxidoreductase - - - 1.203e-201 642.0
TLS3_k127_6327046_3 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 431.0
TLS3_k127_6327046_4 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 418.0
TLS3_k127_6327046_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 364.0
TLS3_k127_6327046_6 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000001007 190.0
TLS3_k127_6327046_7 NlpC/P60 family K13695,K19303 - - 0.000000000000000000000000000000000000000002314 162.0
TLS3_k127_6327046_8 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000309 153.0
TLS3_k127_6327046_9 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000005066 148.0
TLS3_k127_6439466_0 PFAM VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004711 249.0
TLS3_k127_6439466_1 toluene tolerance family protein K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000001203 228.0
TLS3_k127_6439466_2 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000004092 199.0
TLS3_k127_6439466_3 ABC transporter permease K02066 - - 0.000000000000000000000000000000000000003644 147.0
TLS3_k127_6471192_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 1.441e-312 969.0
TLS3_k127_6471192_1 Tripartite tricarboxylate transporter TctA family K07793 - - 4.258e-215 677.0
TLS3_k127_6471192_10 abc transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 327.0
TLS3_k127_6471192_11 Ammonia monooxygenase K07120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 333.0
TLS3_k127_6471192_12 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000006454 117.0
TLS3_k127_6471192_13 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000003743 107.0
TLS3_k127_6471192_15 Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers K07518 - 3.1.1.22 0.0000005263 51.0
TLS3_k127_6471192_2 ABC-type branched-chain amino acid transport systems periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 585.0
TLS3_k127_6471192_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 463.0
TLS3_k127_6471192_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007516 428.0
TLS3_k127_6471192_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 392.0
TLS3_k127_6471192_6 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 391.0
TLS3_k127_6471192_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 396.0
TLS3_k127_6471192_8 Amino acid amide ABC transporter ATP-binding protein 2, HAAT family K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 373.0
TLS3_k127_6471192_9 PFAM conserved K07795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 359.0
TLS3_k127_6502576_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 2.838e-195 614.0
TLS3_k127_6502576_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 504.0
TLS3_k127_6502576_2 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 284.0
TLS3_k127_6502576_3 (FHA) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005101 244.0
TLS3_k127_6502576_4 Protein of unknown function (DUF2889) - - - 0.0000000000000000000000000000000000000000000000000000000000000003357 224.0
TLS3_k127_6502576_5 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000003067 214.0
TLS3_k127_6502576_6 Modulates RecA activity K03565 - - 0.000000000000000000000000000007421 126.0
TLS3_k127_6502576_7 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000172 70.0
TLS3_k127_6603567_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 479.0
TLS3_k127_6603567_1 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 469.0
TLS3_k127_6603567_2 of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 309.0
TLS3_k127_6603567_3 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000003892 124.0
TLS3_k127_662719_0 Outer membrane usher protein K07347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 411.0
TLS3_k127_662719_1 CHAD - - - 0.000000000000000000000000000000000000000000000000000000000000004878 236.0
TLS3_k127_662719_2 Pili and flagellar-assembly chaperone, PapD N-terminal domain K07346 - - 0.00000000000000001317 90.0
TLS3_k127_662719_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000001503 83.0
TLS3_k127_662719_4 Spore Coat Protein U domain - - - 0.000000000131 70.0
TLS3_k127_6639436_0 Peptidase M61 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 583.0
TLS3_k127_6639436_1 amino acid K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008827 452.0
TLS3_k127_6639436_2 alcohol dehydrogenase K19745 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 417.0
TLS3_k127_6639436_3 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009111 406.0
TLS3_k127_6639436_4 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 338.0
TLS3_k127_6639436_5 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008981 271.0
TLS3_k127_6639436_6 - - - - 0.0000000000000000006366 86.0
TLS3_k127_6676748_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 362.0
TLS3_k127_6727878_0 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 6.05e-221 694.0
TLS3_k127_6727878_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 530.0
TLS3_k127_6727878_2 Trap-type c4-dicarboxylate transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000504 273.0
TLS3_k127_6727878_3 AzlC protein - - - 0.0000000000000000000000000000000000000000000000001824 184.0
TLS3_k127_6727878_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000004115 110.0
TLS3_k127_6727878_5 Protein of unknown function (DUF4236) - - - 0.00000000000000001181 93.0
TLS3_k127_6727878_6 Branched-chain amino acid transport protein (AzlD) - - - 0.00000000000000003173 86.0
TLS3_k127_6728258_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 496.0
TLS3_k127_6728258_1 dihydroorotase multifunctional complex type K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 495.0
TLS3_k127_6728258_2 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000002565 186.0
TLS3_k127_6728258_3 PFAM phosphoribosyltransferase K02825 - 2.4.2.9 0.000000000000000000000001685 104.0
TLS3_k127_6769728_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 348.0
TLS3_k127_6769728_1 2-Keto-4-pentenoate hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 325.0
TLS3_k127_6769728_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009983 293.0
TLS3_k127_6769728_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000003774 179.0
TLS3_k127_6769728_4 - - - - 0.0000000000000000001675 94.0
TLS3_k127_6769728_5 protein kinase activity - - - 0.000000000000000001335 100.0
TLS3_k127_6769728_6 - - - - 0.00000007749 61.0
TLS3_k127_6821221_0 short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 394.0
TLS3_k127_6821221_1 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 344.0
TLS3_k127_6836381_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1425.0
TLS3_k127_6836381_1 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 3.013e-245 763.0
TLS3_k127_6836381_10 Twin-arginine translocation pathway signal sequence - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 382.0
TLS3_k127_6836381_11 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 360.0
TLS3_k127_6836381_12 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 334.0
TLS3_k127_6836381_13 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 302.0
TLS3_k127_6836381_14 Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002821 274.0
TLS3_k127_6836381_15 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001687 270.0
TLS3_k127_6836381_16 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000006043 258.0
TLS3_k127_6836381_17 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000009355 231.0
TLS3_k127_6836381_18 Domain of unknown function (DUF1905) - - - 0.00000000000000000000000000000000000000000000000000000000000001291 220.0
TLS3_k127_6836381_19 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000002048 211.0
TLS3_k127_6836381_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 5.085e-218 687.0
TLS3_k127_6836381_20 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000003341 213.0
TLS3_k127_6836381_21 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000797 176.0
TLS3_k127_6836381_22 Shikimate kinase K00851 - 2.7.1.12 0.00000000000000000000000000000000000000000000009507 173.0
TLS3_k127_6836381_23 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000001019 168.0
TLS3_k127_6836381_24 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.00000000000000000000000000000000000000000001838 168.0
TLS3_k127_6836381_25 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000006685 148.0
TLS3_k127_6836381_26 Peptidase M22 glycoprotease K14742 - - 0.0000000000000000000000000000000000002684 156.0
TLS3_k127_6836381_27 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000001553 136.0
TLS3_k127_6836381_28 Outer membrane protein beta-barrel domain - - - 0.0000000000000000003574 95.0
TLS3_k127_6836381_29 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000001301 51.0
TLS3_k127_6836381_3 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 2.248e-210 664.0
TLS3_k127_6836381_4 Belongs to the thiolase family K00626 - 2.3.1.9 6.672e-196 618.0
TLS3_k127_6836381_5 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 556.0
TLS3_k127_6836381_6 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000791 452.0
TLS3_k127_6836381_7 Periplasmic domain of Sensor histidine kinase RisS K07638 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 418.0
TLS3_k127_6836381_8 response regulator K02483,K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 396.0
TLS3_k127_6836381_9 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 384.0
TLS3_k127_683751_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000921 516.0
TLS3_k127_683751_1 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 512.0
TLS3_k127_683751_2 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 454.0
TLS3_k127_683751_3 Type II/IV secretion system protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 460.0
TLS3_k127_683751_4 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 422.0
TLS3_k127_683751_5 RNA cap guanine-N2 methyltransferase K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000001089 222.0
TLS3_k127_683751_6 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000809 212.0
TLS3_k127_688282_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005925 455.0
TLS3_k127_688282_1 Protein of unknown function (DUF3455) - - - 0.0000000000000000000000000000000000000001614 155.0
TLS3_k127_688282_2 - - - - 0.000000000000000000000000000000000000003423 158.0
TLS3_k127_688282_3 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000001006 140.0
TLS3_k127_6902395_0 Transposase DDE domain - - - 9.277e-207 653.0
TLS3_k127_6902395_1 von Willebrand factor (vWF) type A domain - - - 0.0000007917 52.0
TLS3_k127_6920033_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.0 1067.0
TLS3_k127_6920033_1 Peptidase, M20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 601.0
TLS3_k127_6920033_10 PFAM DoxX family protein K15977 - - 0.0000000000000000000000000000000000000000000969 163.0
TLS3_k127_6920033_11 Protein of unknown function (DUF615) K09889 - - 0.0000000000000000000000000000000000006272 145.0
TLS3_k127_6920033_2 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 392.0
TLS3_k127_6920033_3 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 331.0
TLS3_k127_6920033_4 Phospholipase/Carboxylesterase K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 304.0
TLS3_k127_6920033_5 Serine hydrolase (FSH1) K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 291.0
TLS3_k127_6920033_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001245 267.0
TLS3_k127_6920033_7 Diguanylate cyclase phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000001111 239.0
TLS3_k127_6920033_8 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000000414 183.0
TLS3_k127_6920033_9 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000001918 187.0
TLS3_k127_6925750_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1424.0
TLS3_k127_6925750_1 Efflux transporter, outer membrane factor lipoprotein, NodT family K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009175 360.0
TLS3_k127_6925750_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 339.0
TLS3_k127_6925750_3 PFAM regulatory protein TetR K03577 - - 0.0000000000000000000000000000000000000000000000008088 182.0
TLS3_k127_6925750_4 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000005906 142.0
TLS3_k127_6925750_5 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000002695 71.0
TLS3_k127_6941705_0 Pfam:Nol1_Nop2_Fmu K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 523.0
TLS3_k127_6941705_1 fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 518.0
TLS3_k127_6941705_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 488.0
TLS3_k127_6941705_3 mechanosensitive K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 354.0
TLS3_k127_6941705_4 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 311.0
TLS3_k127_6941705_5 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000000001764 183.0
TLS3_k127_6941705_6 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000000000000006528 151.0
TLS3_k127_6941705_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000001113 100.0
TLS3_k127_6941705_8 Methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.000002823 52.0
TLS3_k127_6957845_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.723e-275 857.0
TLS3_k127_6957845_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 9.806e-201 634.0
TLS3_k127_6957845_10 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001232 241.0
TLS3_k127_6957845_11 Ami_2 K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000004601 224.0
TLS3_k127_6957845_12 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000001251 145.0
TLS3_k127_6957845_13 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000001703 131.0
TLS3_k127_6957845_14 - K06950 - - 0.00000000001201 67.0
TLS3_k127_6957845_15 - - - - 0.0006429 45.0
TLS3_k127_6957845_2 type II secretion system protein E K02454,K02504,K02652,K12276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 573.0
TLS3_k127_6957845_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007735 538.0
TLS3_k127_6957845_4 Sigma-54 interaction domain K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 539.0
TLS3_k127_6957845_5 GTP1/OBG K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 473.0
TLS3_k127_6957845_6 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 380.0
TLS3_k127_6957845_7 His Kinase A (phosphoacceptor) domain K02668,K10125 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 343.0
TLS3_k127_6957845_8 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008702 293.0
TLS3_k127_6957845_9 Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002006 247.0
TLS3_k127_6958193_0 reductase, alpha subunit K00394 - 1.8.99.2 0.0 1176.0
TLS3_k127_6958193_1 PUA-like domain K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 447.0
TLS3_k127_6958193_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 351.0
TLS3_k127_6958193_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007083 325.0
TLS3_k127_6958193_4 reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 315.0
TLS3_k127_6958193_5 belongs to the CobB CobQ family K13788 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 312.0
TLS3_k127_6958193_6 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000002762 238.0
TLS3_k127_6958193_7 - - - - 0.0000000000000000000000000000000000000000007361 160.0
TLS3_k127_6958193_8 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000001051 88.0
TLS3_k127_6958193_9 - - - - 0.00000000000005925 72.0
TLS3_k127_6997175_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 4.593e-294 907.0
TLS3_k127_6997175_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 7.51e-209 653.0
TLS3_k127_6997175_2 COG0524 Sugar kinases, ribokinase family K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 432.0
TLS3_k127_6997175_3 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 327.0
TLS3_k127_6997175_4 YGGT family K02221 - - 0.000000000000000000000000000000000000002075 155.0
TLS3_k127_6997175_5 zinc-ribbon domain - - - 0.00000000000000000000000000000000004823 150.0
TLS3_k127_6997175_6 Histone H1-like nucleoprotein HC2 K11275 - - 0.00000000002754 69.0
TLS3_k127_7009283_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 457.0
TLS3_k127_7009283_1 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000002115 228.0
TLS3_k127_7036804_0 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005017 286.0
TLS3_k127_7036804_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000005039 187.0
TLS3_k127_7081820_0 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009042 441.0
TLS3_k127_7081820_1 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000001433 122.0
TLS3_k127_7081820_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00001551 48.0
TLS3_k127_7082508_0 TIGRFAM hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 350.0
TLS3_k127_7082508_1 DNA polymerase III, delta' K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000008243 248.0
TLS3_k127_7082508_2 PilZ domain K02676 - - 0.00000000000000000000000000000000000000000008498 169.0
TLS3_k127_7082508_3 - - - - 0.0000000000000000000000006964 115.0
TLS3_k127_7082508_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000002153 81.0
TLS3_k127_7093368_0 Prolyl oligopeptidase family - - - 5.706e-229 731.0
TLS3_k127_7093368_1 PFAM ATP-binding region, ATPase domain protein K07641 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008259 436.0
TLS3_k127_7093368_2 Transcriptional regulatory protein, C terminal K07663 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 287.0
TLS3_k127_7093368_3 B12 binding domain K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001246 277.0
TLS3_k127_7093368_4 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000002811 183.0
TLS3_k127_7093368_5 - - - - 0.0000000000000000005722 94.0
TLS3_k127_7093368_6 Domain of unknown function (DUF1840) - - - 0.000000000001323 72.0
TLS3_k127_71156_0 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000003094 194.0
TLS3_k127_71156_1 SnoaL-like domain K06893 - - 0.00000000000000000000000000000000000000000000000002032 182.0
TLS3_k127_71156_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000001096 157.0
TLS3_k127_71156_3 TfoX N-terminal domain - - - 0.0000000000000000000000000001726 117.0
TLS3_k127_71156_4 - - - - 0.00000000000000000001074 98.0
TLS3_k127_71156_5 - - - - 0.00001083 51.0
TLS3_k127_71156_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0001254 50.0
TLS3_k127_716306_0 helicase superfamily c-terminal domain K03724 - - 2.984e-275 865.0
TLS3_k127_716306_1 Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single strand break in duplex DNA K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 4.992e-219 698.0
TLS3_k127_716306_2 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 526.0
TLS3_k127_716306_3 phenylacetate-CoA ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000006235 214.0
TLS3_k127_716306_4 - - - - 0.0000000000000000000001944 102.0
TLS3_k127_7174190_0 long-chain fatty acid transport protein - - - 2.895e-306 970.0
TLS3_k127_7174190_1 - - - - 0.00000000000000000000000000000000000001557 166.0
TLS3_k127_7174190_2 amine dehydrogenase activity - - - 0.00000000007016 76.0
TLS3_k127_7194957_0 Histidine kinase-like ATPases - - - 4.594e-237 792.0
TLS3_k127_7194957_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006123 279.0
TLS3_k127_7194957_2 - - - - 0.0000000000000000000000000000000000000000001107 164.0
TLS3_k127_7249474_0 Vitamin K epoxide reductase family - - - 0.0 1047.0
TLS3_k127_7249474_1 Glycosyl hydrolases family 2, sugar binding domain K01190 - 3.2.1.23 0.0 1007.0
TLS3_k127_7249474_10 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008509 374.0
TLS3_k127_7249474_11 Predicted membrane protein (DUF2254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 386.0
TLS3_k127_7249474_12 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 376.0
TLS3_k127_7249474_13 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 373.0
TLS3_k127_7249474_14 SMP-30 Gluconolaconase K14274 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009377 353.0
TLS3_k127_7249474_15 lipopolysaccharide transmembrane transporter activity K03466,K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 306.0
TLS3_k127_7249474_16 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006125 266.0
TLS3_k127_7249474_17 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000002602 259.0
TLS3_k127_7249474_18 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000004458 256.0
TLS3_k127_7249474_19 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000944 237.0
TLS3_k127_7249474_2 Belongs to the IlvD Edd family K01687,K13875,K22186 - 4.2.1.25,4.2.1.82,4.2.1.9 3.812e-289 897.0
TLS3_k127_7249474_20 SelR domain K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000004005 218.0
TLS3_k127_7249474_21 Cysteine-rich secretory protein family - - - 0.000000000000000000000000000000000000000000000000000000000001306 220.0
TLS3_k127_7249474_22 Alpha/beta hydrolase family K07020 - - 0.0000000000000000000000000000000000000000000001718 176.0
TLS3_k127_7249474_23 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000000000178 163.0
TLS3_k127_7249474_24 GCN5-related N-acetyl-transferase K06975 - - 0.000000000000000000000006721 105.0
TLS3_k127_7249474_25 - - - - 0.00000000000000004331 86.0
TLS3_k127_7249474_3 Glucose / Sorbosone dehydrogenase - - - 1.007e-201 640.0
TLS3_k127_7249474_4 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 599.0
TLS3_k127_7249474_5 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 576.0
TLS3_k127_7249474_6 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 559.0
TLS3_k127_7249474_7 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 540.0
TLS3_k127_7249474_8 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 445.0
TLS3_k127_7249474_9 nuclear-transcribed mRNA catabolic process, no-go decay - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 423.0
TLS3_k127_7319332_0 Iron-containing alcohol dehydrogenase K00043,K13954 - 1.1.1.1,1.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 612.0
TLS3_k127_7319332_1 Binding-protein-dependent transport system inner membrane component K02050,K15552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000523 459.0
TLS3_k127_7319332_2 FCD K19776 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 386.0
TLS3_k127_7319332_3 Transposase DDE domain - - - 0.00000000000000000000000001007 112.0
TLS3_k127_7319332_4 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000002977 107.0
TLS3_k127_7319332_5 Binding-protein-dependent transport system inner membrane component K02050,K15552 - - 0.000000008757 61.0
TLS3_k127_7366050_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 531.0
TLS3_k127_7366050_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 427.0
TLS3_k127_7366050_2 Domain of unknown function (DUF4382) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 324.0
TLS3_k127_7366050_3 - - - - 0.0000000000000000000000000004343 119.0
TLS3_k127_7366050_5 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.00000000000000000002889 93.0
TLS3_k127_7366050_6 ribosome binding - - - 0.0000002455 57.0
TLS3_k127_7371062_0 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 431.0
TLS3_k127_7371062_1 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 331.0
TLS3_k127_7436576_0 NADH-quinone oxidoreductase K00336 - 1.6.5.3 7.014e-319 993.0
TLS3_k127_7436576_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 5.394e-292 910.0
TLS3_k127_7436576_2 Catalyzes the transfer of electrons from NADH to quinone K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 580.0
TLS3_k127_7436576_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 530.0
TLS3_k127_7436576_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 535.0
TLS3_k127_7436576_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 298.0
TLS3_k127_7436576_6 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000006603 216.0
TLS3_k127_7436576_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000009901 155.0
TLS3_k127_7455856_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 385.0
TLS3_k127_7455856_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000004451 180.0
TLS3_k127_7455856_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000002619 73.0
TLS3_k127_7519530_0 Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers K07518 - 3.1.1.22 5.72e-231 732.0
TLS3_k127_7523995_0 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 497.0
TLS3_k127_7523995_1 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 396.0
TLS3_k127_7523995_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 379.0
TLS3_k127_7523995_3 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 306.0
TLS3_k127_7523995_4 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000001283 242.0
TLS3_k127_7523995_5 D-amino acid K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000002494 233.0
TLS3_k127_753846_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 3.638e-200 638.0
TLS3_k127_753846_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 529.0
TLS3_k127_753846_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009471 461.0
TLS3_k127_753846_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000005052 117.0
TLS3_k127_753846_4 - - - - 0.000000000000001156 84.0
TLS3_k127_753846_5 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000617 78.0
TLS3_k127_753846_6 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme - - - 0.00000000006143 70.0
TLS3_k127_7616813_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 8.682e-268 840.0
TLS3_k127_7695799_0 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 413.0
TLS3_k127_7695799_1 - - - - 0.00000000000000000000000000000000000000000000000006524 182.0
TLS3_k127_7695799_2 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000001509 119.0
TLS3_k127_7763132_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 532.0
TLS3_k127_7763132_1 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003578 266.0
TLS3_k127_7763132_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000101 192.0
TLS3_k127_7763132_3 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000007053 177.0
TLS3_k127_7763132_4 Histidine kinase - - - 0.0000000000000000008672 100.0
TLS3_k127_7763132_5 Smr protein MutS2 - - - 0.000000000000000001402 91.0
TLS3_k127_7779099_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 9.322e-311 968.0
TLS3_k127_7779099_1 Tripartite tricarboxylate transporter TctA family - - - 1.145e-243 760.0
TLS3_k127_7779099_10 Zinc-binding dehydrogenase K00001,K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007835 266.0
TLS3_k127_7779099_11 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002774 260.0
TLS3_k127_7779099_12 Glycosyl transferase group 2 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001125 249.0
TLS3_k127_7779099_13 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000006466 228.0
TLS3_k127_7779099_14 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000002837 213.0
TLS3_k127_7779099_15 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000000000000000009621 173.0
TLS3_k127_7779099_16 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000007367 141.0
TLS3_k127_7779099_17 Transmembrane anti-sigma factor - - - 0.000000008401 60.0
TLS3_k127_7779099_2 gamma-glutamyltransferase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 3.847e-219 692.0
TLS3_k127_7779099_3 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 493.0
TLS3_k127_7779099_4 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 454.0
TLS3_k127_7779099_5 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006558 445.0
TLS3_k127_7779099_6 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 377.0
TLS3_k127_7779099_7 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000795 333.0
TLS3_k127_7779099_8 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 293.0
TLS3_k127_7779099_9 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003893 288.0
TLS3_k127_7820248_0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 343.0
TLS3_k127_7820248_1 KR domain K00034 - 1.1.1.47 0.00000000000000000000000000000000000000000000000000000001041 200.0
TLS3_k127_7820248_2 - - - - 0.0000000000000000000001228 104.0
TLS3_k127_7837986_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 4.119e-287 889.0
TLS3_k127_7837986_1 carboxylase K01965,K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.3,6.4.1.4 2.846e-250 790.0
TLS3_k127_7837986_10 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 296.0
TLS3_k127_7837986_11 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009077 267.0
TLS3_k127_7837986_12 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000002671 261.0
TLS3_k127_7837986_13 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000004411 252.0
TLS3_k127_7837986_14 rod shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000000000000000000000000000001771 236.0
TLS3_k127_7837986_15 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000003622 235.0
TLS3_k127_7837986_16 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000000000000000004118 214.0
TLS3_k127_7837986_17 Auxin-binding protein - - - 0.000000000000000000000000000000000000000000000000000000008867 208.0
TLS3_k127_7837986_18 Thioesterase K18700 - 3.1.2.29 0.000000000000000000000000000000000000000000000004551 175.0
TLS3_k127_7837986_19 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000001312 178.0
TLS3_k127_7837986_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 6.195e-215 676.0
TLS3_k127_7837986_20 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000001362 171.0
TLS3_k127_7837986_21 Protein of unknown function (DUF3617) - - - 0.00000000000000000000000000001262 123.0
TLS3_k127_7837986_22 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000008736 120.0
TLS3_k127_7837986_23 - - - - 0.0000000000000000006766 96.0
TLS3_k127_7837986_24 Tetratricopeptide repeat - - - 0.00000001333 66.0
TLS3_k127_7837986_25 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.0000002889 54.0
TLS3_k127_7837986_26 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.000004933 49.0
TLS3_k127_7837986_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 6.357e-206 653.0
TLS3_k127_7837986_4 Cell shape determining protein, MreB Mrl family K03569 - - 1.205e-200 629.0
TLS3_k127_7837986_5 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 599.0
TLS3_k127_7837986_6 Major facilitator superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 559.0
TLS3_k127_7837986_7 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 523.0
TLS3_k127_7837986_8 HMGL-like K01640 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 428.0
TLS3_k127_7837986_9 Enoyl-CoA hydratase/isomerase K13766,K15312 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 346.0
TLS3_k127_7844676_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 352.0
TLS3_k127_7844676_1 Methyltransferase domain - - - 0.00000000000000000000000004349 115.0
TLS3_k127_7863009_0 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000146 229.0
TLS3_k127_7863009_1 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000004794 198.0
TLS3_k127_7863009_2 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000002701 113.0
TLS3_k127_7863009_3 SMART metal-dependent phosphohydrolase, HD region K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000008266 88.0
TLS3_k127_7874536_0 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000002928 244.0
TLS3_k127_7874536_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000002766 137.0
TLS3_k127_7874536_2 Endoribonuclease L-PSP - - - 0.00000000000000000005805 94.0
TLS3_k127_7897137_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 7.947e-199 629.0
TLS3_k127_7897137_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 609.0
TLS3_k127_7897137_10 PAP2 superfamily K19302 - 3.6.1.27 0.00000000000000000000000000000000000000001112 161.0
TLS3_k127_7897137_11 Transglycosylase associated protein - - - 0.000000000000000000000000000000000001496 142.0
TLS3_k127_7897137_12 Protein of unknown function, DUF417 K21741 - - 0.000000000000000000000000000000000001553 145.0
TLS3_k127_7897137_13 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000002565 139.0
TLS3_k127_7897137_14 - - - - 0.000000000000000000000000000000228 137.0
TLS3_k127_7897137_15 Periplasmic or secreted lipoprotein K04065 - - 0.00000000000000000000000001311 112.0
TLS3_k127_7897137_16 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000000001528 116.0
TLS3_k127_7897137_17 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000004841 109.0
TLS3_k127_7897137_18 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000003392 94.0
TLS3_k127_7897137_19 - - - - 0.0000000000000000037 90.0
TLS3_k127_7897137_2 Dead deah box helicase domain protein K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005412 499.0
TLS3_k127_7897137_3 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 488.0
TLS3_k127_7897137_4 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 430.0
TLS3_k127_7897137_5 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 384.0
TLS3_k127_7897137_6 PFAM glycosyl transferase group 1 K02844,K14335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 327.0
TLS3_k127_7897137_7 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000001417 252.0
TLS3_k127_7897137_8 deacetylase K06986 - - 0.0000000000000000000000000000000000000000000000000000000000000000203 233.0
TLS3_k127_7897137_9 Domain of unknown function (DUF2383) - - - 0.00000000000000000000000000000000000000000000000000000003252 199.0
TLS3_k127_7900805_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 478.0
TLS3_k127_7900805_1 Peptidyl-prolyl cis-trans K03774 - 5.2.1.8 0.0000000000000000000000008777 106.0
TLS3_k127_7900805_2 Chalcone isomerase-like - - - 0.0000000000000001782 83.0
TLS3_k127_8057749_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 449.0
TLS3_k127_8057749_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008239 334.0
TLS3_k127_8057749_2 PFAM Hemerythrin HHE cation binding domain protein - - - 0.0000000000000000000000000000000000000000000000004826 184.0
TLS3_k127_8057749_3 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000000000003954 85.0
TLS3_k127_8057749_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000006473 69.0
TLS3_k127_8057749_5 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0000000005694 61.0
TLS3_k127_8057749_6 - - - - 0.0000000005872 69.0
TLS3_k127_8105353_0 Protein of unknown function (DUF456) K09793 - - 0.00000000000000000000000000000000000000001651 155.0
TLS3_k127_8105353_1 Protein of unknown function (DUF2846) - - - 0.0000000000000000000000000000000002479 138.0
TLS3_k127_8105353_2 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000004197 117.0
TLS3_k127_8105353_3 - - - - 0.0000000000000004074 86.0
TLS3_k127_8112500_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 7.691e-246 778.0
TLS3_k127_8112500_1 DEAD/DEAH box helicase K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 548.0
TLS3_k127_8112500_2 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 305.0
TLS3_k127_8113040_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 0.0 1109.0
TLS3_k127_8113040_1 acyl-CoA dehydrogenase - - - 9.523e-271 846.0
TLS3_k127_8113040_10 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 380.0
TLS3_k127_8113040_11 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 336.0
TLS3_k127_8113040_12 Binding-protein-dependent transport system inner membrane component K02029,K10003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009516 319.0
TLS3_k127_8113040_13 Binding-protein-dependent transport system inner membrane component K10002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 316.0
TLS3_k127_8113040_14 PFAM Enoyl-CoA hydratase isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 315.0
TLS3_k127_8113040_15 dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 293.0
TLS3_k127_8113040_16 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 286.0
TLS3_k127_8113040_17 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000105 287.0
TLS3_k127_8113040_18 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001006 246.0
TLS3_k127_8113040_19 Amino acid ABC transporter substrate-binding protein K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000005413 242.0
TLS3_k127_8113040_2 ABC transporter transmembrane region K06147 - - 1.745e-254 797.0
TLS3_k127_8113040_20 Calcineurin-like phosphoesterase K06953 - - 0.0000000000000000000000000000000000000000000000000000000000000023 229.0
TLS3_k127_8113040_21 Thioesterase superfamily K10806 - - 0.00000000000000000000000000000000000000000000000001413 188.0
TLS3_k127_8113040_22 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000001122 174.0
TLS3_k127_8113040_23 Membrane K15977 - - 0.0000000000000000000000000000000000000000000006477 169.0
TLS3_k127_8113040_24 TraB family K09973 - - 0.000000000000000000000000000000000000000000123 173.0
TLS3_k127_8113040_25 Limonene-1,2-epoxide hydrolase catalytic domain - - - 0.0000000000000000000000000000000002202 138.0
TLS3_k127_8113040_26 OmpA-like transmembrane domain - - - 0.000000000004853 74.0
TLS3_k127_8113040_3 Belongs to the thiolase family K00632 - 2.3.1.16 2.944e-204 642.0
TLS3_k127_8113040_4 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 615.0
TLS3_k127_8113040_5 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009882 544.0
TLS3_k127_8113040_6 Bacterial periplasmic substrate-binding proteins K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006412 429.0
TLS3_k127_8113040_7 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 417.0
TLS3_k127_8113040_8 ABC-type polar amino acid transport system, ATPase component K10004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 400.0
TLS3_k127_8113040_9 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 396.0
TLS3_k127_8136743_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 528.0
TLS3_k127_8141517_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1448.0
TLS3_k127_8141517_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 8.823e-314 969.0
TLS3_k127_8141517_10 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 448.0
TLS3_k127_8141517_11 ribonuclease BN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 373.0
TLS3_k127_8141517_12 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 332.0
TLS3_k127_8141517_13 Inner membrane protein CreD K06143 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 317.0
TLS3_k127_8141517_14 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 304.0
TLS3_k127_8141517_15 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002109 278.0
TLS3_k127_8141517_16 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.000000000000000000000000000000000000000000000000000003789 192.0
TLS3_k127_8141517_17 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000004638 184.0
TLS3_k127_8141517_18 succinate dehydrogenase, hydrophobic membrane anchor protein K00242 - - 0.00000000000000000000000000000000002747 143.0
TLS3_k127_8141517_19 Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.00000000000000000000000000000000006845 138.0
TLS3_k127_8141517_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 1.885e-313 969.0
TLS3_k127_8141517_20 - - - - 0.000000000000000002948 95.0
TLS3_k127_8141517_21 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000000474 87.0
TLS3_k127_8141517_22 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000002147 80.0
TLS3_k127_8141517_3 2-methylcitrate dehydratase K01720 - 4.2.1.79 2.362e-262 814.0
TLS3_k127_8141517_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.346e-247 768.0
TLS3_k127_8141517_5 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 1.565e-229 715.0
TLS3_k127_8141517_6 Belongs to the citrate synthase family K01659 - 2.3.3.5 6.156e-201 631.0
TLS3_k127_8141517_7 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 580.0
TLS3_k127_8141517_8 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 534.0
TLS3_k127_8141517_9 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 467.0
TLS3_k127_8158934_0 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.0 1371.0
TLS3_k127_8158934_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1211.0
TLS3_k127_8158934_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 340.0
TLS3_k127_8158934_3 PFAM Hemerythrin HHE cation binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000009066 204.0
TLS3_k127_8158934_5 transcriptional regulator - - - 0.0000000347 58.0
TLS3_k127_8187837_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1349.0
TLS3_k127_8187837_1 Belongs to the ClpA ClpB family K03694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 556.0
TLS3_k127_8187837_2 Sulfide dehydrogenase K05301,K17218 - 1.8.2.1,1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 492.0
TLS3_k127_8187837_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 462.0
TLS3_k127_8187837_4 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 368.0
TLS3_k127_8187837_5 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000003052 252.0
TLS3_k127_8187837_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000009548 213.0
TLS3_k127_8187837_7 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000001776 145.0
TLS3_k127_8187837_8 Cytochrome c, class I - - - 0.000000000000000000003003 97.0
TLS3_k127_8205744_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0 1557.0
TLS3_k127_8205744_1 Alpha-amylase domain K01187 - 3.2.1.20 0.0 1472.0
TLS3_k127_8205744_10 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006398 582.0
TLS3_k127_8205744_11 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 554.0
TLS3_k127_8205744_12 PFAM Glycoside hydrolase 15-related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 558.0
TLS3_k127_8205744_13 Major facilitator superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 526.0
TLS3_k127_8205744_14 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 504.0
TLS3_k127_8205744_15 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 504.0
TLS3_k127_8205744_16 Histidine kinase K20974 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 454.0
TLS3_k127_8205744_17 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 426.0
TLS3_k127_8205744_18 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 401.0
TLS3_k127_8205744_19 Protein of unknown function (DUF1428) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 370.0
TLS3_k127_8205744_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1088.0
TLS3_k127_8205744_20 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 360.0
TLS3_k127_8205744_21 mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 362.0
TLS3_k127_8205744_22 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 342.0
TLS3_k127_8205744_23 converts alpha-aldose to the beta-anomer - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 319.0
TLS3_k127_8205744_24 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 300.0
TLS3_k127_8205744_25 ROK family K00886 - 2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 298.0
TLS3_k127_8205744_26 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 289.0
TLS3_k127_8205744_27 Membrane K07027 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007133 271.0
TLS3_k127_8205744_28 PFAM Conserved TM helix repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006945 250.0
TLS3_k127_8205744_29 Cupin - - - 0.0000000000000000000000000000000000000000000000000003156 186.0
TLS3_k127_8205744_3 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 1.041e-305 953.0
TLS3_k127_8205744_30 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000006176 185.0
TLS3_k127_8205744_31 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000005669 169.0
TLS3_k127_8205744_32 - - - - 0.0000000000000000000000000000000000000000007642 161.0
TLS3_k127_8205744_33 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000001191 142.0
TLS3_k127_8205744_34 Heavy-metal-associated domain K08364 - - 0.0000000000000000000000000000000006372 134.0
TLS3_k127_8205744_35 Protein of unknown function (DUF2799) - - - 0.000000000000000000000000002314 120.0
TLS3_k127_8205744_36 (Lipo)protein - - - 0.0000000000000000000000003131 112.0
TLS3_k127_8205744_37 Glutaredoxin - - - 0.00000000002381 70.0
TLS3_k127_8205744_38 COG0457 FOG TPR repeat - - - 0.0000000001492 66.0
TLS3_k127_8205744_4 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 6.351e-305 944.0
TLS3_k127_8205744_5 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 1.444e-293 914.0
TLS3_k127_8205744_6 Sulfatase K01130 - 3.1.6.1 4.324e-227 711.0
TLS3_k127_8205744_7 trehalohydrolase K01236 - 3.2.1.141 8.351e-227 719.0
TLS3_k127_8205744_8 FMN-dependent dehydrogenase K00101 GO:0002218,GO:0002253,GO:0002376,GO:0002682,GO:0002684,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006950,GO:0006952,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0010204,GO:0016999,GO:0017000,GO:0017144,GO:0023052,GO:0031347,GO:0031349,GO:0042579,GO:0042742,GO:0042743,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0045088,GO:0045089,GO:0048518,GO:0048583,GO:0048584,GO:0050665,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0072593,GO:0080134,GO:0098542,GO:1903409 1.1.2.3 3.855e-214 670.0
TLS3_k127_8205744_9 PAS fold - - - 6.572e-202 652.0
TLS3_k127_8210798_0 Acyclic terpene utilisation family protein AtuA - - - 2.194e-203 641.0
TLS3_k127_8210798_1 tRNA-splicing ligase RtcB K14415 GO:0003674,GO:0003824,GO:0003909,GO:0005488,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0030145,GO:0033554,GO:0034641,GO:0042245,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:0140098,GO:1901360 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 458.0
TLS3_k127_8210798_10 Cupin 2, conserved barrel domain protein K11312 - - 0.0000000000000000000000000000000000000000000000000000985 192.0
TLS3_k127_8210798_11 - - - - 0.00000000000000000000000000000000000000000000000004171 181.0
TLS3_k127_8210798_12 Glutaredoxin - - - 0.00000000001114 70.0
TLS3_k127_8210798_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 456.0
TLS3_k127_8210798_3 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 432.0
TLS3_k127_8210798_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 391.0
TLS3_k127_8210798_5 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 351.0
TLS3_k127_8210798_6 PFAM Ribulose bisphosphate carboxylase large chain K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 349.0
TLS3_k127_8210798_7 Diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 342.0
TLS3_k127_8210798_8 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 313.0
TLS3_k127_8210798_9 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000000000000000000000001975 203.0
TLS3_k127_8230578_0 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 332.0
TLS3_k127_8230578_1 Oxidoreductase molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 341.0
TLS3_k127_8230578_2 Histidine kinase K02484,K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 328.0
TLS3_k127_8230578_3 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.00000000000000000000000000000000000001298 146.0
TLS3_k127_8230806_0 GTP-binding protein K06207 - - 8.2e-322 995.0
TLS3_k127_8230806_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 332.0
TLS3_k127_8230806_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 310.0
TLS3_k127_8230806_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001026 263.0
TLS3_k127_8230806_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000009137 144.0
TLS3_k127_8230806_5 KR domain - - - 0.0001808 48.0
TLS3_k127_8292429_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 463.0
TLS3_k127_8292429_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 354.0
TLS3_k127_8292429_2 lipase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001006 274.0
TLS3_k127_8292429_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000008185 240.0
TLS3_k127_8310567_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1065.0
TLS3_k127_8310567_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.388e-286 896.0
TLS3_k127_8310567_2 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 314.0
TLS3_k127_8310567_3 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000008214 83.0
TLS3_k127_8389858_0 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 531.0
TLS3_k127_8389858_1 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009446 431.0
TLS3_k127_8389858_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000001167 95.0
TLS3_k127_8390464_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 431.0
TLS3_k127_8390464_1 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000003135 225.0
TLS3_k127_8390464_2 Sugar isomerase (SIS) - - - 0.0000000000000000000000000000000000000000000000000000000006831 214.0
TLS3_k127_8404724_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 447.0
TLS3_k127_8404724_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 402.0
TLS3_k127_8413572_0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 417.0
TLS3_k127_8413572_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 377.0
TLS3_k127_8413572_2 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 319.0
TLS3_k127_8413572_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000862 197.0
TLS3_k127_8413572_4 GNAT family acetyltransferase - - - 0.000000000000000000000000000000000000000000000006335 182.0
TLS3_k127_8413572_5 ATP synthase B/B' CF(0) K02109 - - 0.0000000000000000000000000000000000000001963 159.0
TLS3_k127_8413572_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000000006121 143.0
TLS3_k127_8413572_7 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000001969 115.0
TLS3_k127_8413572_8 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000402 98.0
TLS3_k127_8413572_9 ATP synthase I chain K02116 - - 0.0000002512 58.0
TLS3_k127_8417137_0 ABC transporter C-terminal domain K06158 - - 2.972e-254 798.0
TLS3_k127_8417137_1 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.00000000000000000000000000000000000000000000000000000006704 199.0
TLS3_k127_8417137_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000001254 199.0
TLS3_k127_8418709_0 Molydopterin dinucleotide binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 594.0
TLS3_k127_8418709_1 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 563.0
TLS3_k127_8418709_2 amino acid transport system, ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 425.0
TLS3_k127_8418709_3 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006191 303.0
TLS3_k127_8418709_5 Protein of unknown function (DUF3455) - - - 0.00000000000000000000006801 105.0
TLS3_k127_8418723_0 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 309.0
TLS3_k127_8418723_1 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000001822 173.0
TLS3_k127_8418723_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000001317 99.0
TLS3_k127_8468917_0 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000003091 198.0
TLS3_k127_8468917_1 Bacterial transcriptional activator domain - - - 0.00000001312 61.0
TLS3_k127_8490480_0 Bacterial protein of unknown function (DUF853) K06915 - - 5.973e-226 718.0
TLS3_k127_8490480_1 ribonuclease, Rne Rng family K08301 - - 8.715e-222 696.0
TLS3_k127_8490480_10 ABC-2 family transporter protein K09696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002843 294.0
TLS3_k127_8490480_11 ATPases associated with a variety of cellular activities K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001711 266.0
TLS3_k127_8490480_12 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000001264 222.0
TLS3_k127_8490480_13 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000000001203 190.0
TLS3_k127_8490480_14 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000002053 175.0
TLS3_k127_8490480_15 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000004227 168.0
TLS3_k127_8490480_16 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000008085 178.0
TLS3_k127_8490480_17 - - - - 0.0000000000000000000000000000000000000000002201 166.0
TLS3_k127_8490480_18 YHS domain - - - 0.0000000000000000000000000000000000000004427 153.0
TLS3_k127_8490480_19 - - - - 0.0000000000000000000000000000000004634 136.0
TLS3_k127_8490480_2 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008318 556.0
TLS3_k127_8490480_20 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000002168 126.0
TLS3_k127_8490480_3 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 482.0
TLS3_k127_8490480_4 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 444.0
TLS3_k127_8490480_5 PFAM AAA ATPase central domain protein K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 426.0
TLS3_k127_8490480_6 TAP-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 389.0
TLS3_k127_8490480_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 361.0
TLS3_k127_8490480_8 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 347.0
TLS3_k127_8490480_9 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 299.0
TLS3_k127_8554121_0 Polysaccharide biosynthesis/export protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 618.0
TLS3_k127_868686_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 612.0
TLS3_k127_868686_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 422.0
TLS3_k127_868686_2 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 363.0
TLS3_k127_868686_3 DNA polymerase alpha chain like domain K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 336.0
TLS3_k127_868686_4 NlpB/DapX lipoprotein K07287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 333.0
TLS3_k127_868686_5 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 289.0
TLS3_k127_868686_6 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006983 277.0
TLS3_k127_868686_7 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000002562 196.0
TLS3_k127_868686_8 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000006909 186.0
TLS3_k127_905101_0 cheY-homologous receiver domain K02657 - - 0.0000000000000000000000000000000000000000000000000000000000004977 213.0
TLS3_k127_905101_1 cheY-homologous receiver domain K02658 - - 0.0000000000000000000000000000000000000000000000000000008873 194.0
TLS3_k127_905101_2 CheW-like domain K02659 - - 0.00000000000000000000000000000000306 135.0
TLS3_k127_905101_3 Rubredoxin - - - 0.0000000000000000000000000000005203 123.0
TLS3_k127_905101_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000006559 81.0
TLS3_k127_935476_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 371.0
TLS3_k127_935476_1 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 328.0
TLS3_k127_938597_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 7.818e-271 857.0
TLS3_k127_938597_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637 589.0
TLS3_k127_938597_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 427.0
TLS3_k127_942680_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1113.0
TLS3_k127_942680_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 4.786e-277 865.0
TLS3_k127_942680_10 Domain of unknown function (DUF4212) - - - 0.000000000000000000002595 95.0
TLS3_k127_942680_11 - - - - 0.000000000000003705 79.0
TLS3_k127_942680_2 MgsA AAA+ ATPase C terminal K07478 - - 1.311e-196 621.0
TLS3_k127_942680_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 9.445e-195 615.0
TLS3_k127_942680_4 Protein of unknown function (DUF808) K09781 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 390.0
TLS3_k127_942680_5 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 360.0
TLS3_k127_942680_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000000000000000000000000000002727 226.0
TLS3_k127_942680_7 FKBP-type peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000012 208.0
TLS3_k127_942680_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000007592 128.0
TLS3_k127_942680_9 Dodecin K09165 - - 0.00000000000000000000002859 100.0
TLS3_k127_966176_0 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 0.0 1748.0
TLS3_k127_966176_1 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1670.0
TLS3_k127_966176_10 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 319.0
TLS3_k127_966176_11 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 289.0
TLS3_k127_966176_12 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000008989 244.0
TLS3_k127_966176_13 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.000000000000000000000000000000000000000000000000000000000000000005307 241.0
TLS3_k127_966176_14 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000008821 191.0
TLS3_k127_966176_15 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.00000000000000000000000000000000000002052 149.0
TLS3_k127_966176_16 BolA-like protein K05527 - - 0.00000000000000000000007741 101.0
TLS3_k127_966176_2 Activates fatty acids by binding to coenzyme A K20034 - 6.2.1.44 1.546e-263 822.0
TLS3_k127_966176_3 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 599.0
TLS3_k127_966176_4 Belongs to the UPF0061 (SELO) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 586.0
TLS3_k127_966176_5 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 535.0
TLS3_k127_966176_6 amino acid K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 521.0
TLS3_k127_966176_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 416.0
TLS3_k127_966176_8 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 410.0
TLS3_k127_966176_9 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 347.0
TLS3_k127_986434_0 trisaccharide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 392.0
TLS3_k127_986434_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000005379 206.0
TLS3_k127_986434_2 DNA-templated transcription, initiation K02405 - - 0.0000000000000000000000000000000003082 139.0