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Overview

ID MAG04038
Name TLS3_bin.14
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Dehalococcoidia
Order Tepidiformales
Family Tepidiformaceae
Genus Tepidiforma
Species
Assembly information
Completeness (%) 84.58
Contamination (%) 2.61
GC content (%) 65.0
N50 (bp) 10,591
Genome size (bp) 3,117,281

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2941

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1003118_0 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 340.0
TLS3_k127_1003118_1 UDP binding domain K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 320.0
TLS3_k127_1003118_2 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000002329 172.0
TLS3_k127_1003118_3 CoA-transferase family III K07544,K07749 - 2.8.3.15,2.8.3.16 0.0000000000000000000000000000000000000001964 169.0
TLS3_k127_1003118_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000008073 103.0
TLS3_k127_1003118_5 succinyl-CoA glutarate-CoA transferase K18703 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0008410,GO:0016740,GO:0016782,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0047369 2.8.3.13 0.000007861 59.0
TLS3_k127_1004067_0 acyl-CoA transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 311.0
TLS3_k127_1004067_1 Zn-dependent proteases and their inactivated homologs K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004818 252.0
TLS3_k127_1004067_2 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000002208 192.0
TLS3_k127_1004067_3 MOSC domain - - - 0.00000000000000000000000000000000000000004557 162.0
TLS3_k127_1005828_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 551.0
TLS3_k127_1005828_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000001323 221.0
TLS3_k127_1005828_2 FAD binding domain - - - 0.00000000000000000000000000000000000000000001553 177.0
TLS3_k127_1005828_3 FAE1/Type III polyketide synthase-like protein K16167 - - 0.00000000000000000000000000000000000000000003422 175.0
TLS3_k127_1005828_4 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K16168 - - 0.0000000000000000000000000000004141 128.0
TLS3_k127_1005828_5 PFAM Methyltransferase type 12 - - - 0.00000546 48.0
TLS3_k127_1033277_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001067 260.0
TLS3_k127_1033277_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000294 147.0
TLS3_k127_1033277_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000004179 145.0
TLS3_k127_1033277_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000001271 111.0
TLS3_k127_1033277_4 pyridoxamine 5-phosphate K07005 - - 0.00000000000006365 80.0
TLS3_k127_1033277_5 helix_turn_helix, Lux Regulon - - - 0.00000004316 64.0
TLS3_k127_1053568_0 PFAM carboxyl transferase K15052 - 2.1.3.15,6.4.1.3 1.701e-253 791.0
TLS3_k127_1053568_1 Acetyl propionyl-CoA carboxylase, alpha subunit K11263 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.4.14,6.4.1.2,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 468.0
TLS3_k127_1053568_2 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 394.0
TLS3_k127_1053568_3 Aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 342.0
TLS3_k127_1053568_4 PHB de-polymerase C-terminus K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000009567 244.0
TLS3_k127_1059774_0 DNA repair - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 352.0
TLS3_k127_1059774_1 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 321.0
TLS3_k127_1059774_2 ABC-type Mn2 Zn2 transport systems permease components K09819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003699 260.0
TLS3_k127_1059774_3 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001204 243.0
TLS3_k127_1059774_4 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.00000000000000000000000000000000000000000000000000000000000000000004571 244.0
TLS3_k127_1059774_5 PFAM ABC transporter related K11710 - - 0.000000000000000000000000000000000000000000000000000000000000003292 225.0
TLS3_k127_1059774_6 Transcriptional regulator - - - 0.00000000000000000000000000000000006443 141.0
TLS3_k127_1059774_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000004885 85.0
TLS3_k127_1062971_0 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000006376 168.0
TLS3_k127_1062971_1 ADP-ribose pyrophosphatase - - - 0.0000000000000000000000000000000000000001222 157.0
TLS3_k127_1062971_2 MoaE protein K21142 - 2.8.1.12 0.00000000000000000000000000000000002998 144.0
TLS3_k127_1062971_3 RibD C-terminal domain - - - 0.0000000000000000000000000000000009708 139.0
TLS3_k127_1062971_4 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000008668 66.0
TLS3_k127_1062971_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 GO:0008150,GO:0040007 1.2.1.70 0.0000000001612 72.0
TLS3_k127_107395_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 2.784e-260 816.0
TLS3_k127_107395_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 356.0
TLS3_k127_107395_10 Protein of unknown function (DUF402) K09145 - - 0.0000000000000000000000001713 116.0
TLS3_k127_107395_11 YGGT family K02221 - - 0.00000000001954 67.0
TLS3_k127_107395_12 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000002486 66.0
TLS3_k127_107395_13 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000003595 63.0
TLS3_k127_107395_14 membrane K02221 - - 0.000000006268 62.0
TLS3_k127_107395_15 Lrp/AsnC ligand binding domain - - - 0.000000006378 60.0
TLS3_k127_107395_16 Plasmid stabilization system - - - 0.0000008127 56.0
TLS3_k127_107395_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 315.0
TLS3_k127_107395_3 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000001865 236.0
TLS3_k127_107395_4 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000001326 217.0
TLS3_k127_107395_5 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000008619 210.0
TLS3_k127_107395_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000008793 189.0
TLS3_k127_107395_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000639 145.0
TLS3_k127_107395_8 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000002318 133.0
TLS3_k127_107395_9 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000007533 142.0
TLS3_k127_1081412_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 8.677e-222 704.0
TLS3_k127_1081412_1 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 339.0
TLS3_k127_1081412_2 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000004609 170.0
TLS3_k127_1081412_3 Zn-dependent alcohol dehydrogenases K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000002341 164.0
TLS3_k127_1081412_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000002064 70.0
TLS3_k127_1095647_0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 374.0
TLS3_k127_1095647_1 domain-containing protein K08869 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001981 276.0
TLS3_k127_1095647_2 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000001928 157.0
TLS3_k127_1095647_3 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000005825 128.0
TLS3_k127_1098504_0 ABC transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 380.0
TLS3_k127_1098504_1 protein conserved in bacteria - - - 0.000000000002126 79.0
TLS3_k127_1105317_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006373 283.0
TLS3_k127_1105317_1 PFAM transcriptional activator domain - - - 0.0000000000000000000001802 114.0
TLS3_k127_1105317_2 Family of unknown function (DUF5317) - - - 0.0004649 49.0
TLS3_k127_1109831_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 429.0
TLS3_k127_1109831_1 TIGRFAM primosome, DnaD subunit - - - 0.0000000000000000000000000000000000003255 149.0
TLS3_k127_1109831_2 Thioesterase-like superfamily - - - 0.000000000000000000000000000004748 121.0
TLS3_k127_1109831_3 Binds to the 23S rRNA K02939 - - 0.000000000000000000000000003594 119.0
TLS3_k127_1153518_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000001239 241.0
TLS3_k127_1153518_1 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000003086 175.0
TLS3_k127_1153518_2 COG1030 Membrane-bound serine protease (ClpP class) K07403 - - 0.00000000000001665 79.0
TLS3_k127_1156418_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 502.0
TLS3_k127_1156418_1 arginyl-tRNA aminoacylation K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 355.0
TLS3_k127_1156418_2 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000000000000000000000000001978 218.0
TLS3_k127_1156418_3 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000004569 173.0
TLS3_k127_1156418_4 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000001294 141.0
TLS3_k127_1156418_5 Protein of unknown function (DUF429) - - - 0.0000000000000000005901 99.0
TLS3_k127_1156418_6 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate - - - 0.00000000000000000102 96.0
TLS3_k127_1156418_7 Probable molybdopterin binding domain - - - 0.000000000002147 69.0
TLS3_k127_1195216_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 512.0
TLS3_k127_1195216_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 318.0
TLS3_k127_1195216_10 Protein of unknown function (DUF402) K07586 - - 0.00000001931 66.0
TLS3_k127_1195216_11 DinB superfamily - - - 0.00005102 52.0
TLS3_k127_1195216_12 Rhodanese Homology Domain - - - 0.0003718 44.0
TLS3_k127_1195216_2 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 317.0
TLS3_k127_1195216_3 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000002885 175.0
TLS3_k127_1195216_4 4Fe-4S binding domain - - - 0.00000000000000000000000000000227 132.0
TLS3_k127_1195216_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000001417 113.0
TLS3_k127_1195216_6 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000006466 91.0
TLS3_k127_1195216_7 Protein of unknown function (DUF433) - - - 0.00000000001152 70.0
TLS3_k127_1195216_8 phosphate regulon transcriptional regulatory protein PhoB K07657 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000001076 71.0
TLS3_k127_1195216_9 - - - - 0.000000000168 67.0
TLS3_k127_1231411_0 PFAM ABC transporter related K01990,K09691,K09693 - 3.6.3.40 0.000000000000000000000000000000000000000000000000000000000000000000007831 246.0
TLS3_k127_1231411_1 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000001131 215.0
TLS3_k127_1231411_2 ABC-2 type transporter K09688,K09690 - - 0.00000000000000000000000000000000000000000000000005865 188.0
TLS3_k127_1231411_3 Glycosyl transferase, family 2 K07011 - - 0.0000000000000000000000000000000000000000000000001608 188.0
TLS3_k127_1233128_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 506.0
TLS3_k127_1233128_2 Sporulation and spore germination - - - 0.00000000000000000000000000000000000000000000000000000008865 206.0
TLS3_k127_1233128_3 Bacterial regulatory protein, arsR family - - - 0.000000000000000000000000009453 113.0
TLS3_k127_1258586_0 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 445.0
TLS3_k127_1258586_1 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 385.0
TLS3_k127_1258586_2 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000006335 207.0
TLS3_k127_1258586_3 transmembrane transport K01992 - - 0.000000000000000000000000000000000000000000000000004169 191.0
TLS3_k127_1258586_4 Protein of unknown function (DUF2938) - - - 0.0000000000000000000000000000000000000000000009158 177.0
TLS3_k127_1258586_5 trisaccharide binding K03556 - - 0.000000000000000000000000000000000000000004474 158.0
TLS3_k127_1258586_6 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000000002788 161.0
TLS3_k127_1258586_7 - - - - 0.00000000000000000000000000000001107 139.0
TLS3_k127_1258586_8 - - - - 0.000000000000000001529 89.0
TLS3_k127_1275983_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 394.0
TLS3_k127_1275983_1 Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000002525 180.0
TLS3_k127_1275983_2 Thioesterase superfamily - - - 0.00000000000000000000000000000000002015 139.0
TLS3_k127_1297889_0 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006346 277.0
TLS3_k127_1297889_1 PFAM MotA TolQ ExbB proton channel K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000004539 237.0
TLS3_k127_1297889_10 Role in flagellar biosynthesis K02420 - - 0.0000000000000000001774 90.0
TLS3_k127_1297889_11 Flagellar biosynthesis protein, FliO K02418 - - 0.0000000000001379 79.0
TLS3_k127_1297889_12 PFAM flagellar FlbD family protein K02385 - - 0.0000000000003615 72.0
TLS3_k127_1297889_13 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000003291 71.0
TLS3_k127_1297889_14 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000005602 56.0
TLS3_k127_1297889_15 PQ loop repeat K15383 - - 0.000222 48.0
TLS3_k127_1297889_2 helix_turn_helix, Lux Regulon K02282 - - 0.00000000000000000000000000000000000000000000000000000000004076 215.0
TLS3_k127_1297889_3 PFAM OmpA MotB domain protein K02557 - - 0.0000000000000000000000000000000000000000000003286 176.0
TLS3_k127_1297889_4 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000000009615 155.0
TLS3_k127_1297889_5 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000005836 147.0
TLS3_k127_1297889_6 flagellar biosynthetic protein FliR K02421 - - 0.000000000000000000000000000000000006634 149.0
TLS3_k127_1297889_7 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401,K13820 - - 0.000000000000000000000000006536 115.0
TLS3_k127_1297889_8 Flagellar motor switch protein FliM K02417 GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032879,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051270,GO:0065007,GO:0071704,GO:0140096,GO:1901564,GO:1902021,GO:2000145 - 0.0000000000000000000000002595 118.0
TLS3_k127_1297889_9 acetyltransferase K00657 - 2.3.1.57 0.000000000000000000001167 102.0
TLS3_k127_1312732_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1034.0
TLS3_k127_1312732_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 323.0
TLS3_k127_1312732_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 309.0
TLS3_k127_1312732_3 Steryl acetyl hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 295.0
TLS3_k127_1312732_4 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007344 272.0
TLS3_k127_1312732_5 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000003732 241.0
TLS3_k127_1312732_6 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000001998 171.0
TLS3_k127_1312732_7 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000002358 103.0
TLS3_k127_1312732_8 Sugar (and other) transporter - - - 0.0000000000000001707 92.0
TLS3_k127_1312732_9 FtsX-like permease family K02004 - - 0.000000000000808 74.0
TLS3_k127_135148_0 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 436.0
TLS3_k127_135148_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 370.0
TLS3_k127_135148_10 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000002274 116.0
TLS3_k127_135148_11 SPTR D1C1B9 DinB family protein - - - 0.000000000000000001577 94.0
TLS3_k127_135148_12 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000004258 67.0
TLS3_k127_135148_13 DinB superfamily - - - 0.00001651 53.0
TLS3_k127_135148_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 311.0
TLS3_k127_135148_3 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 308.0
TLS3_k127_135148_4 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 303.0
TLS3_k127_135148_5 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002233 274.0
TLS3_k127_135148_6 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001247 287.0
TLS3_k127_135148_7 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000001683 226.0
TLS3_k127_135148_8 AhpC/TSA family K03564 - 1.11.1.15 0.000000000000000000000000000000000000000004732 159.0
TLS3_k127_135148_9 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000005543 130.0
TLS3_k127_1381405_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005794 538.0
TLS3_k127_1381405_1 Efflux ABC transporter, permease protein - - - 0.00000000027 70.0
TLS3_k127_1476405_0 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1179.0
TLS3_k127_1476405_1 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 489.0
TLS3_k127_1476405_10 Htaa - - - 0.000000000000000000000000000000000008047 144.0
TLS3_k127_1476405_11 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000001933 143.0
TLS3_k127_1476405_12 Protein of unknown function (DUF2470) - - - 0.000000000000000000000000001027 117.0
TLS3_k127_1476405_13 SNARE associated Golgi protein - - - 0.0000000000000000211 93.0
TLS3_k127_1476405_14 Protein of unknown function (DUF983) - - - 0.000000000000000225 90.0
TLS3_k127_1476405_15 protein possibly involved in aromatic compounds catabolism - - - 0.0000000006641 68.0
TLS3_k127_1476405_16 nuclease activity K06218 - - 0.000000006119 60.0
TLS3_k127_1476405_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 417.0
TLS3_k127_1476405_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 413.0
TLS3_k127_1476405_4 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 324.0
TLS3_k127_1476405_5 Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006721 307.0
TLS3_k127_1476405_6 Heme oxygenase K21480 - 1.14.15.20 0.000000000000000000000000000000000000000000000000001716 190.0
TLS3_k127_1476405_7 pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000000000003633 176.0
TLS3_k127_1476405_8 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000000003287 178.0
TLS3_k127_1476405_9 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000002355 175.0
TLS3_k127_1570275_0 DEAD DEAH box helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 385.0
TLS3_k127_1570275_1 extracellular solute-binding protein, family 3 K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 325.0
TLS3_k127_1614309_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000001481 191.0
TLS3_k127_1614309_1 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000001358 155.0
TLS3_k127_1614309_2 general stress protein - - - 0.0000000006143 66.0
TLS3_k127_1614309_3 Response regulator receiver domain - - - 0.00000003948 66.0
TLS3_k127_1618476_0 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 312.0
TLS3_k127_1618476_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 295.0
TLS3_k127_1618476_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005312 270.0
TLS3_k127_1619391_0 epoxide hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 466.0
TLS3_k127_1619391_1 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 415.0
TLS3_k127_1619391_2 alginic acid biosynthetic process K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009188 286.0
TLS3_k127_1619391_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K07218 - - 0.0000000000000000000000000000000000000000000001563 180.0
TLS3_k127_1619391_4 ABC-2 family transporter protein K01992,K19341 - - 0.0000000000000000000000000000000000000000004127 168.0
TLS3_k127_1619391_5 SnoaL-like domain - - - 0.00000000000000000000000000005341 123.0
TLS3_k127_1619391_6 lipoprotein involved in nitrous oxide reduction - - - 0.000000000000000000000000173 123.0
TLS3_k127_1619391_7 lipoprotein involved in nitrous oxide reduction K19342 - - 0.000000000000000000001657 100.0
TLS3_k127_1619391_8 Response regulator receiver K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000003119 100.0
TLS3_k127_1619391_9 Uncharacterized conserved protein (DUF2249) - - - 0.00000000001785 68.0
TLS3_k127_1633767_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 2.246e-195 624.0
TLS3_k127_1633767_1 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008649 307.0
TLS3_k127_1633767_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000805 236.0
TLS3_k127_1633767_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000003774 183.0
TLS3_k127_1633767_4 membrane transporter protein K07090 - - 0.000000000000000000000000000000001485 146.0
TLS3_k127_1633767_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000003755 104.0
TLS3_k127_1633767_6 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000001404 108.0
TLS3_k127_1633767_7 TIGRFAM 3-oxoacyl-(acyl-carrier-protein) reductase K00059 - 1.1.1.100 0.00000000002042 64.0
TLS3_k127_1633767_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000001182 59.0
TLS3_k127_1634857_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 598.0
TLS3_k127_1634857_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006093 568.0
TLS3_k127_1634857_2 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001752 268.0
TLS3_k127_1634857_3 Glycosyltransferase family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 0.00000000000000000000000000000000000000000000000004189 198.0
TLS3_k127_1634857_4 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000001741 145.0
TLS3_k127_1634857_5 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000002536 98.0
TLS3_k127_1634857_7 Bacterial regulatory proteins, tetR family - - - 0.00000000006939 71.0
TLS3_k127_1634857_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0003401 51.0
TLS3_k127_1701443_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.027e-232 737.0
TLS3_k127_1701443_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 378.0
TLS3_k127_1701443_2 PFAM Mur ligase, middle domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 366.0
TLS3_k127_1701443_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 309.0
TLS3_k127_1701443_4 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000009403 166.0
TLS3_k127_1701443_5 Transcriptional regulator PadR-like family - - - 0.0000000000000000000002249 101.0
TLS3_k127_1701443_6 - - - - 0.0000000000242 72.0
TLS3_k127_1727026_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 319.0
TLS3_k127_1727026_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000134 255.0
TLS3_k127_1727026_2 15-hydroxyprostaglandin dehydrogenase (NAD+) activity K00069 GO:0000003,GO:0000166,GO:0001568,GO:0001655,GO:0001676,GO:0001822,GO:0001944,GO:0002237,GO:0003674,GO:0003824,GO:0004888,GO:0004930,GO:0004953,GO:0004954,GO:0004955,GO:0004957,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0006690,GO:0006692,GO:0006693,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007186,GO:0007275,GO:0007276,GO:0007292,GO:0007565,GO:0007567,GO:0008150,GO:0008152,GO:0008284,GO:0008610,GO:0009058,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0010941,GO:0010942,GO:0014070,GO:0016053,GO:0016404,GO:0016491,GO:0016614,GO:0016616,GO:0019372,GO:0019752,GO:0019953,GO:0022414,GO:0023052,GO:0030728,GO:0031974,GO:0031981,GO:0032355,GO:0032496,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0033559,GO:0033993,GO:0035239,GO:0035295,GO:0036094,GO:0038023,GO:0042127,GO:0042221,GO:0042493,GO:0042759,GO:0042802,GO:0042803,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043167,GO:0043168,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044421,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0045471,GO:0045786,GO:0046394,GO:0046456,GO:0046677,GO:0046983,GO:0048037,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048609,GO:0048660,GO:0048661,GO:0048731,GO:0048844,GO:0048856,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051287,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0055114,GO:0060089,GO:0060840,GO:0065007,GO:0070013,GO:0070403,GO:0070493,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0072001,GO:0072330,GO:0072358,GO:0072359,GO:0097070,GO:0097159,GO:0097305,GO:1901265,GO:1901363,GO:1901568,GO:1901570,GO:1901576,GO:1901700,GO:1904705,GO:1904707,GO:2001300,GO:2001301 1.1.1.141 0.00000000000000000000000000000000000000000000004781 186.0
TLS3_k127_1727026_3 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000001215 184.0
TLS3_k127_1727026_4 Enoyl-CoA hydratase/isomerase K01692,K13766 - 4.2.1.17,4.2.1.18 0.0000000000000000000000000000000000000000008208 168.0
TLS3_k127_1727026_5 methyltransferase K21459 - 2.1.1.301 0.00000000000000000000000000000000000000004398 161.0
TLS3_k127_1727026_6 - - - - 0.00000000000000002358 84.0
TLS3_k127_1727026_7 - - - - 0.0000000000000002135 85.0
TLS3_k127_1762647_0 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003173 246.0
TLS3_k127_1762647_1 Belongs to the ComB family K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.000000000000000000000003609 112.0
TLS3_k127_1762647_2 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.000000000004482 76.0
TLS3_k127_1774947_0 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007875 278.0
TLS3_k127_1774947_1 YjbR - - - 0.0000000000000000000000000000000000000000000000000002337 188.0
TLS3_k127_1774947_2 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000777 194.0
TLS3_k127_1774947_3 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.00000000000000000000000001392 122.0
TLS3_k127_1774947_4 deaminated base DNA N-glycosylase activity K21929 - 3.2.2.27 0.0000000000000000000000248 107.0
TLS3_k127_1774947_5 helix_turn_helix, Lux Regulon K07694,K11618 - - 0.000000000928 68.0
TLS3_k127_1774947_6 DinB family - - - 0.0000466 52.0
TLS3_k127_1781794_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 578.0
TLS3_k127_1781794_1 ADP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 467.0
TLS3_k127_1781794_10 PFAM TspO MBR family K05770 - - 0.0000000000000000000000000000000000000006692 159.0
TLS3_k127_1781794_11 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000000000000000000000000005119 121.0
TLS3_k127_1781794_12 Domain of unknown function (DUF378) - - - 0.000000000001177 72.0
TLS3_k127_1781794_13 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000239 55.0
TLS3_k127_1781794_16 Regulatory protein - - - 0.0006609 49.0
TLS3_k127_1781794_2 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 452.0
TLS3_k127_1781794_3 ig-like, plexins, transcription factors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 347.0
TLS3_k127_1781794_4 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009067 324.0
TLS3_k127_1781794_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 310.0
TLS3_k127_1781794_6 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007601 258.0
TLS3_k127_1781794_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000002097 174.0
TLS3_k127_1781794_8 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000004646 158.0
TLS3_k127_1781794_9 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX K17759 - 5.1.99.6 0.0000000000000000000000000000000000000003662 158.0
TLS3_k127_1797713_0 COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily) K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 334.0
TLS3_k127_1797713_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000003058 237.0
TLS3_k127_1797713_10 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000004214 60.0
TLS3_k127_1797713_2 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000000000000000287 177.0
TLS3_k127_1797713_3 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000004138 166.0
TLS3_k127_1797713_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000003266 128.0
TLS3_k127_1797713_6 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000004003 114.0
TLS3_k127_1797713_7 nuclease activity - - - 0.0000000000000000000000008212 109.0
TLS3_k127_1797713_8 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000243 102.0
TLS3_k127_1828748_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 503.0
TLS3_k127_1828748_1 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 480.0
TLS3_k127_1828748_10 Transcription factor zinc-finger K09981 - - 0.0000000000000000007119 88.0
TLS3_k127_1828748_11 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000003674 77.0
TLS3_k127_1828748_12 Two component transcriptional regulator, LuxR family - - - 0.0000008931 61.0
TLS3_k127_1828748_13 peptidylprolyl isomerase K03769 - 5.2.1.8 0.000013 57.0
TLS3_k127_1828748_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 426.0
TLS3_k127_1828748_3 homoserine dehydrogenase NAD-binding K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 381.0
TLS3_k127_1828748_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000004348 238.0
TLS3_k127_1828748_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000004212 213.0
TLS3_k127_1828748_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000008604 203.0
TLS3_k127_1828748_7 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000001159 153.0
TLS3_k127_1828748_8 - - - - 0.00000000000000000000000000004102 122.0
TLS3_k127_1828748_9 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000001514 106.0
TLS3_k127_183184_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K12953 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.8 8.189e-286 903.0
TLS3_k127_183184_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 470.0
TLS3_k127_183184_2 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 439.0
TLS3_k127_183184_3 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 397.0
TLS3_k127_183184_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 343.0
TLS3_k127_183184_5 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007624 283.0
TLS3_k127_183184_6 PFAM Cyclic nucleotide-binding K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000000000000000000000000000000000000000000001256 177.0
TLS3_k127_183184_7 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000008417 154.0
TLS3_k127_183184_8 PFAM UspA - - - 0.0002986 51.0
TLS3_k127_1835858_0 Flavoprotein involved in K transport K03379 - 1.14.13.22 5.634e-227 716.0
TLS3_k127_1856700_0 PFAM Retinal pigment epithelial membrane protein K11159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 579.0
TLS3_k127_1856700_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 301.0
TLS3_k127_1856700_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001353 243.0
TLS3_k127_1856700_3 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000001279 186.0
TLS3_k127_1856700_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000153 174.0
TLS3_k127_1856700_5 CoA binding domain K06929 - - 0.00000000000000000000000000000000004396 140.0
TLS3_k127_1856700_6 4Fe-4S binding domain - - - 0.0000000000000000000000000001005 116.0
TLS3_k127_1856700_7 Class II aldolase adducin family protein K01628 - 4.1.2.17 0.0000000000000000000000000002377 121.0
TLS3_k127_1856700_8 Transcriptional - - - 0.000000000000008187 79.0
TLS3_k127_1857345_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000001806 235.0
TLS3_k127_1857345_1 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002677 241.0
TLS3_k127_1857345_2 Cytochrome P450 K05525,K20497 - 1.14.13.151,1.14.15.14 0.000000000000000000000000000000000000000000000000000000003117 203.0
TLS3_k127_1857345_3 CGNR zinc finger - - - 0.0000000000000000000000008694 110.0
TLS3_k127_1857345_4 protein import - - - 0.0009477 51.0
TLS3_k127_1874072_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008024 400.0
TLS3_k127_1874072_1 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 403.0
TLS3_k127_1874072_10 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.0000000004082 66.0
TLS3_k127_1874072_11 histidine kinase A domain protein - - - 0.0000003846 60.0
TLS3_k127_1874072_12 Protein of unknown function (DUF1706) - - - 0.0001105 50.0
TLS3_k127_1874072_2 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 401.0
TLS3_k127_1874072_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 360.0
TLS3_k127_1874072_4 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003971 278.0
TLS3_k127_1874072_5 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002017 267.0
TLS3_k127_1874072_6 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000006365 214.0
TLS3_k127_1874072_7 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000111 195.0
TLS3_k127_1874072_8 tRNA m6t6A37 methyltransferase activity K11261 - 1.2.7.12 0.00000000000000000000000004482 113.0
TLS3_k127_1874072_9 diguanylate cyclase - - - 0.0000000000000000000003279 110.0
TLS3_k127_1892658_0 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001812 252.0
TLS3_k127_1892658_1 Histidine kinase K02480 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000002604 228.0
TLS3_k127_1892658_2 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000006065 198.0
TLS3_k127_1892658_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000003786 136.0
TLS3_k127_1892658_4 acetyltransferase K03789 - 2.3.1.128 0.00000000000006836 74.0
TLS3_k127_1892658_5 acyl-CoA dehydrogenase - - - 0.00000003699 65.0
TLS3_k127_1897002_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.579e-239 761.0
TLS3_k127_1897002_1 Magnesium chelatase, subunit ChlI K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 601.0
TLS3_k127_1897002_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 516.0
TLS3_k127_1897002_3 histidyl-tRNA aminoacylation K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 376.0
TLS3_k127_1897002_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009175 330.0
TLS3_k127_1897002_5 self proteolysis - - - 0.000000000006074 68.0
TLS3_k127_1931874_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004178 273.0
TLS3_k127_1944147_0 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 303.0
TLS3_k127_1944147_1 - - - - 0.0000000000000000000000000000007814 129.0
TLS3_k127_1949892_0 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000003502 240.0
TLS3_k127_1949892_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000003517 216.0
TLS3_k127_1949892_2 TIM-barrel fold metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000008876 194.0
TLS3_k127_1949892_3 domain protein K20276 - - 0.00000000000000000005885 107.0
TLS3_k127_1949892_4 Conserved repeat domain - - - 0.00000000002388 78.0
TLS3_k127_1949892_5 serine-type aminopeptidase activity - - - 0.000000007065 63.0
TLS3_k127_1963195_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 448.0
TLS3_k127_1963195_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.00000000000000000000000000007104 122.0
TLS3_k127_1963195_2 Phosphotransferase enzyme family K02204 - 2.7.1.39 0.000000000000003259 85.0
TLS3_k127_1963195_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000002305 69.0
TLS3_k127_1973654_0 Multicopper oxidase K22348 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 380.0
TLS3_k127_1973654_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006326 282.0
TLS3_k127_1973654_2 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000006494 265.0
TLS3_k127_1973654_3 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000006742 136.0
TLS3_k127_1973654_4 AAA domain - - - 0.000000000000000000000001225 104.0
TLS3_k127_1973654_5 JAB/MPN domain K21140 - 3.13.1.6 0.000000000000000000008682 105.0
TLS3_k127_1973654_6 Belongs to the universal stress protein A family - - - 0.00000000000000000005035 101.0
TLS3_k127_1973654_7 Belongs to the UPF0337 (CsbD) family - - - 0.000000001611 61.0
TLS3_k127_1973654_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000001157 62.0
TLS3_k127_199366_0 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000001041 241.0
TLS3_k127_199366_1 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000003411 216.0
TLS3_k127_199366_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000006658 216.0
TLS3_k127_199366_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000005722 180.0
TLS3_k127_199366_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000006384 83.0
TLS3_k127_199366_5 Bacterial protein of unknown function (DUF951) - - - 0.0000000000023 74.0
TLS3_k127_199366_6 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.00000000001761 68.0
TLS3_k127_199366_7 COG0477 Permeases of the major facilitator superfamily - - - 0.00004794 55.0
TLS3_k127_2000297_0 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 437.0
TLS3_k127_2000297_1 PFAM CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 377.0
TLS3_k127_2000297_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 321.0
TLS3_k127_2000297_3 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000008213 189.0
TLS3_k127_2000297_4 Belongs to the long-chain O-acyltransferase family - - - 0.000000000000000000000000000000000000000001282 174.0
TLS3_k127_2000297_5 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000002006 137.0
TLS3_k127_2000297_6 permease - - - 0.000000000000000000000000004665 124.0
TLS3_k127_2000297_7 Protein of unknown function (DUF1706) - - - 0.0000000000000000000009234 99.0
TLS3_k127_2000297_8 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000002849 93.0
TLS3_k127_2000297_9 DinB family - - - 0.00000000000004493 79.0
TLS3_k127_2004063_0 Domain of unknown function (DUF1998) K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 462.0
TLS3_k127_2004063_1 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000004242 128.0
TLS3_k127_2004063_2 PFAM ResB family protein K07399 - - 0.0000000747 64.0
TLS3_k127_2031716_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1086.0
TLS3_k127_2031716_1 Highly conserved protein containing a thioredoxin domain K06888 - - 2.292e-240 760.0
TLS3_k127_2031716_10 phosphotransferase activity, carboxyl group as acceptor K03830,K05715 - - 0.00000003783 64.0
TLS3_k127_2031716_2 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 397.0
TLS3_k127_2031716_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 364.0
TLS3_k127_2031716_4 inositol monophosphate 1-phosphatase activity K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000006233 185.0
TLS3_k127_2031716_5 N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000008601 181.0
TLS3_k127_2031716_6 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000001668 165.0
TLS3_k127_2031716_7 PIN domain - - - 0.000000000000000000000000001037 116.0
TLS3_k127_2031716_8 SpoVT / AbrB like domain - - - 0.00000000000000001238 84.0
TLS3_k127_2031716_9 Right handed beta helix region - - - 0.0000000000006091 81.0
TLS3_k127_2040267_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 437.0
TLS3_k127_2040267_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 342.0
TLS3_k127_2040267_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity K00765 GO:0000105,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003879,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016020,GO:0016053,GO:0016208,GO:0016740,GO:0016757,GO:0016763,GO:0017076,GO:0018130,GO:0019438,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0052803,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 330.0
TLS3_k127_2040267_3 Imidazoleglycerol-phosphate dehydratase K00013,K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,2.6.1.9,3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000001926 241.0
TLS3_k127_2040267_4 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000000000000000000000000000000000000001609 233.0
TLS3_k127_2040267_5 Biotin/lipoate A/B protein ligase family - - - 0.000000000000000000000000000000000000000005651 165.0
TLS3_k127_2040267_6 phosphoribosyl-ATP diphosphatase activity K01523,K01814,K11755 GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31,5.3.1.16 0.000000000000000000000000000006833 120.0
TLS3_k127_2040267_7 Transposase - - - 0.0000000000000000000000005583 111.0
TLS3_k127_2040267_8 PIN domain - - - 0.000000000000000002085 89.0
TLS3_k127_2040267_9 positive regulation of growth - - - 0.00007211 49.0
TLS3_k127_20512_0 Baseplate J-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 531.0
TLS3_k127_20512_1 Rhs element vgr protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 301.0
TLS3_k127_20512_2 LysM domain - - - 0.00000000000000000000000000000000000000000000000000001598 196.0
TLS3_k127_20512_3 PFAM GPW gp25 family protein K06903 - - 0.0000000000000000000000000000000000009554 142.0
TLS3_k127_20512_4 Forkhead associated domain - - - 0.00000000000000000000000000000000000174 145.0
TLS3_k127_20512_5 cell adhesion involved in biofilm formation - - - 0.000000000000001199 89.0
TLS3_k127_2051819_0 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 343.0
TLS3_k127_2051819_1 PFAM alanine racemase domain protein K20757 - 4.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000001877 248.0
TLS3_k127_2051819_2 GTPase activity K06207 GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 0.0000000000000000000000000000000005088 134.0
TLS3_k127_2077171_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 401.0
TLS3_k127_2077171_1 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 393.0
TLS3_k127_2077171_2 COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit K13796 - - 0.000000000000000000000000000000000000000007489 158.0
TLS3_k127_2077171_3 Bacterial transcriptional repressor C-terminal - - - 0.0000000000000000000000000000000000000001954 157.0
TLS3_k127_2077171_4 - - - - 0.000000000004557 69.0
TLS3_k127_2077171_5 - - - - 0.000000000006664 68.0
TLS3_k127_2088617_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 385.0
TLS3_k127_2088617_1 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 370.0
TLS3_k127_2088617_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 359.0
TLS3_k127_2088617_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 299.0
TLS3_k127_2088617_5 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003518 249.0
TLS3_k127_2088617_6 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008224 248.0
TLS3_k127_2088617_7 glycogen (starch) synthase activity K08256 - 2.4.1.345 0.000000000000000000000000000000000000000000001221 181.0
TLS3_k127_2088617_9 Peptidase M60-like family - - - 0.0001451 55.0
TLS3_k127_2096890_0 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 323.0
TLS3_k127_2096890_1 nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 294.0
TLS3_k127_2096890_2 Acyl-CoA thioesterase K10805 - - 0.0000000000000000000000000000000000000000000000000000000000000001855 231.0
TLS3_k127_2096890_3 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000001578 172.0
TLS3_k127_2096890_4 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000003712 134.0
TLS3_k127_2096890_5 aminoglycoside hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.00000000000000000000005742 103.0
TLS3_k127_2096890_6 Nucleotidyltransferase domain K07075 - - 0.000000000000000000007581 104.0
TLS3_k127_2096890_7 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000006527 74.0
TLS3_k127_2096890_8 Protein of unknown function DUF86 - - - 0.00000000007618 68.0
TLS3_k127_2099847_0 PFAM type II secretion system protein E K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 482.0
TLS3_k127_2099847_1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000001161 236.0
TLS3_k127_2099847_2 Phosphoesterase, PA-phosphatase related - - - 0.00000000000000002014 94.0
TLS3_k127_2099847_3 TadE-like protein - - - 0.0000000000000005152 85.0
TLS3_k127_2099847_4 PFAM Flp Fap pilin component K02651 - - 0.00000007921 57.0
TLS3_k127_2099847_5 SAF K02279 - - 0.000005684 57.0
TLS3_k127_2099847_6 Putative Flp pilus-assembly TadE/G-like - - - 0.00002394 57.0
TLS3_k127_216323_0 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 581.0
TLS3_k127_216323_1 belongs to the sigma-70 factor family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 457.0
TLS3_k127_216323_10 - - - - 0.0000000000000004305 86.0
TLS3_k127_216323_11 YCII-related domain - - - 0.00000000000002716 81.0
TLS3_k127_216323_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 368.0
TLS3_k127_216323_3 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000007621 227.0
TLS3_k127_216323_4 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000003219 169.0
TLS3_k127_216323_5 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000003183 160.0
TLS3_k127_216323_6 YCII-related domain - - - 0.00000000000000000000000000000000376 137.0
TLS3_k127_216323_7 YCII-related domain - - - 0.00000000000000000000000000000001705 132.0
TLS3_k127_216323_8 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000218 132.0
TLS3_k127_216323_9 Phosphohistidine phosphatase, SixA K08296 - - 0.00000000000000000001579 97.0
TLS3_k127_2172519_0 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 334.0
TLS3_k127_2172519_1 glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000001383 255.0
TLS3_k127_2172519_2 Glycosyltransferase like family 2 K07011,K13659 - 2.4.1.264 0.00000000000000000000000000000000000000000000000000000000000000000009149 248.0
TLS3_k127_2172519_3 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000008102 214.0
TLS3_k127_2172519_4 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.000000000000000000000000000000000001044 142.0
TLS3_k127_2172519_5 Transmembrane secretion effector - - - 0.00000000000000000000000000006367 119.0
TLS3_k127_2172519_6 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000003601 99.0
TLS3_k127_2172519_7 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000001691 91.0
TLS3_k127_2172519_8 PFAM Glycosyl transferase family 2 K07011 - - 0.0000000000002503 80.0
TLS3_k127_2172519_9 UPF0316 protein - - - 0.000000000000273 77.0
TLS3_k127_2183701_0 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 503.0
TLS3_k127_2183701_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 332.0
TLS3_k127_2183701_2 type III restriction protein res subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 310.0
TLS3_k127_2183701_3 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000054 199.0
TLS3_k127_2183701_4 Domain of unknown function (DUF3291) - - - 0.00000000000000000000000000000000000000000000000008597 181.0
TLS3_k127_2183701_5 COG2206 HD-GYP domain - - - 0.000000000000000000000000000000000000000000008903 183.0
TLS3_k127_2183701_6 Rho termination factor, N-terminal domain - - - 0.0000000000000000001077 93.0
TLS3_k127_2229756_0 aromatic amino acid beta-eliminating lyase threonine aldolase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 368.0
TLS3_k127_2229756_1 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily K01897 - 6.2.1.3 0.000000000000000000000000000000002469 136.0
TLS3_k127_2229756_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000004788 57.0
TLS3_k127_2256293_0 Amidohydrolase family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 299.0
TLS3_k127_2256293_1 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000005188 216.0
TLS3_k127_2256293_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000008335 201.0
TLS3_k127_2256293_3 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion K02564 - 3.5.99.6 0.00000000000000000000000000000000000003622 160.0
TLS3_k127_2256293_4 ECF sigma factor K03088 - - 0.000000000000000000000000000000000002708 148.0
TLS3_k127_2256293_5 cell envelope-related transcriptional attenuator - - - 0.000000000000000000000000000000000008644 157.0
TLS3_k127_2256293_6 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000586 120.0
TLS3_k127_2256293_7 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000171 64.0
TLS3_k127_2256293_8 Domain of unknown function (DUF4157) - - - 0.0001486 49.0
TLS3_k127_2262088_0 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 436.0
TLS3_k127_2262088_1 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 342.0
TLS3_k127_2262088_2 PFAM Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001882 270.0
TLS3_k127_2262088_3 Nitroreductase - - - 0.0000000000000000000004678 102.0
TLS3_k127_2262088_4 stress protein (general stress protein 26) - - - 0.00000000000003687 78.0
TLS3_k127_23617_0 PFAM IstB domain protein ATP-binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 358.0
TLS3_k127_23617_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000001181 113.0
TLS3_k127_23617_2 - - - - 0.00000331 54.0
TLS3_k127_2375476_0 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 304.0
TLS3_k127_2375476_1 B12- binding domain protein K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000001359 186.0
TLS3_k127_2375476_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000002118 196.0
TLS3_k127_2375476_3 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.0000000000000000000000000000001196 133.0
TLS3_k127_2375476_4 phosphoglycerate mutase K02226,K22305 - 3.1.3.3,3.1.3.73 0.0000000000000000000000000003749 123.0
TLS3_k127_2375476_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K05606 - 4.4.1.5,5.1.99.1 0.0000000000000000000006886 101.0
TLS3_k127_2375476_6 Luciferase-like monooxygenase - - - 0.000000000000000003667 87.0
TLS3_k127_2375476_7 Septum formation initiator K13052 - - 0.00000009216 58.0
TLS3_k127_2375476_8 FR47-like protein K18816 - 2.3.1.82 0.000008762 55.0
TLS3_k127_2393491_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008888 545.0
TLS3_k127_2393491_1 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009089 284.0
TLS3_k127_2393491_10 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000001465 78.0
TLS3_k127_2393491_11 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000003467 63.0
TLS3_k127_2393491_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 0.00000000000000000000000000000000000000000000001101 181.0
TLS3_k127_2393491_3 diacylglycerol kinase, catalytic region - - - 0.00000000000000000000000000000000000000002414 165.0
TLS3_k127_2393491_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000002031 153.0
TLS3_k127_2393491_5 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000007775 127.0
TLS3_k127_2393491_6 Major facilitator Superfamily - - - 0.00000000000000000000000000003047 132.0
TLS3_k127_2393491_7 Resolvase, N terminal domain K06400 - - 0.00000000000000000001043 106.0
TLS3_k127_2393491_8 - - - - 0.00000000000000002693 91.0
TLS3_k127_2393491_9 Zn-ribbon protein, possibly nucleic acid-binding K07164 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000009213 87.0
TLS3_k127_2424832_0 MMPL family K06994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 604.0
TLS3_k127_2424832_1 ATPase associated with various cellular K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 435.0
TLS3_k127_2424832_2 transcriptional regulator K07721 - - 0.0000000000000000000000000000000000000001871 152.0
TLS3_k127_2424832_3 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000004096 115.0
TLS3_k127_2424832_4 extracellular polysaccharide biosynthetic process K13582 - - 0.0000000000000000000000007369 115.0
TLS3_k127_2424832_5 transcriptional regulator - - - 0.0000000000000000003589 97.0
TLS3_k127_2424832_6 Cupredoxin-like domain - - - 0.000000395 61.0
TLS3_k127_2424832_7 - - - - 0.000002613 56.0
TLS3_k127_2471106_0 domain-containing protein K08869 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 308.0
TLS3_k127_2471106_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000002358 145.0
TLS3_k127_2471106_2 Nucleotidyltransferase domain - - - 0.00000000000000000000000000003238 119.0
TLS3_k127_2471106_3 SnoaL-like domain - - - 0.00000000000000000002445 95.0
TLS3_k127_2471106_4 Protein of unknown function DUF86 - - - 0.0000000000000006895 81.0
TLS3_k127_2471106_5 PFAM Transposase IS200 like K07491 - - 0.0000000000004815 78.0
TLS3_k127_2471106_6 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000004544 54.0
TLS3_k127_2471106_7 3-oxoadipate enol-lactonase K01055,K14727 - 3.1.1.24,4.1.1.44 0.0002031 44.0
TLS3_k127_2473312_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003357 275.0
TLS3_k127_2473312_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K14161 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000001541 225.0
TLS3_k127_2473312_2 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000002892 228.0
TLS3_k127_2473312_3 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000002829 171.0
TLS3_k127_2473312_4 PFAM Activator of Hsp90 ATPase 1 family protein - - - 0.0000000000000000000000000000000000002566 145.0
TLS3_k127_2473312_5 Putative Phosphatase - - - 0.00000000000004478 81.0
TLS3_k127_2473312_6 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.0001911 49.0
TLS3_k127_2480375_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008339 442.0
TLS3_k127_2480375_1 PFAM Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000006608 179.0
TLS3_k127_2480375_2 Iron-storage protein K02217 - 1.16.3.2 0.00000000000000000000000000000000000000003545 160.0
TLS3_k127_2480375_3 nucleotidyltransferase activity K07076 - - 0.000000000000000002148 90.0
TLS3_k127_2480375_4 - - - - 0.000000000002058 74.0
TLS3_k127_2480375_5 HEPN domain - - - 0.00000005823 60.0
TLS3_k127_2480375_6 Acetyltransferase (GNAT) family K18816 - 2.3.1.82 0.000001989 54.0
TLS3_k127_2480707_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.953e-235 741.0
TLS3_k127_2480707_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 607.0
TLS3_k127_2480707_10 DinB family - - - 0.00000000000000000000000001078 116.0
TLS3_k127_2480707_11 Phosphotransferase enzyme family - - - 0.000000000000000000000001579 115.0
TLS3_k127_2480707_12 protein with SCP PR1 domains - - - 0.000000000000000001836 95.0
TLS3_k127_2480707_13 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.000000000000003454 87.0
TLS3_k127_2480707_14 Bacterial regulatory proteins, tetR family - - - 0.0000000000001991 78.0
TLS3_k127_2480707_15 Putative regulatory protein - - - 0.000000000004342 71.0
TLS3_k127_2480707_16 Bacterial regulatory proteins, tetR family - - - 0.0000000005313 69.0
TLS3_k127_2480707_17 -acetyltransferase - - - 0.0003474 51.0
TLS3_k127_2480707_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 384.0
TLS3_k127_2480707_3 homoserine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 350.0
TLS3_k127_2480707_4 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 344.0
TLS3_k127_2480707_5 ferredoxin-thioredoxin reductase activity K17892 GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015979,GO:0016491,GO:0016730,GO:0022900,GO:0030385,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 1.8.7.2 0.0000000000000000000000000000000000000000000000000205 192.0
TLS3_k127_2480707_6 hydrolase activity, acting on ester bonds K15357,K19311 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0044237,GO:0044248 3.5.1.106 0.0000000000000000000000000000000000000000000000003242 187.0
TLS3_k127_2480707_7 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000003583 168.0
TLS3_k127_2480707_8 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000006158 143.0
TLS3_k127_2480707_9 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000003765 132.0
TLS3_k127_2496711_0 receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 401.0
TLS3_k127_2496711_1 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000001502 201.0
TLS3_k127_2496711_2 Unextendable partial coding region - - - 0.0000000000000000003889 88.0
TLS3_k127_2496711_3 COG NOG14600 non supervised orthologous group - - - 0.00000000000000001791 81.0
TLS3_k127_2505918_0 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.00000000000000000001154 95.0
TLS3_k127_2505918_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000001379 88.0
TLS3_k127_2505918_2 Cupin domain - - - 0.000000001608 64.0
TLS3_k127_250809_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1265.0
TLS3_k127_250809_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000003715 119.0
TLS3_k127_250809_2 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.0000003189 63.0
TLS3_k127_250809_3 PFAM GCN5-related N-acetyltransferase - - - 0.0001147 53.0
TLS3_k127_253562_0 Biotin carboxylase C-terminal domain - - - 4.987e-233 732.0
TLS3_k127_253562_1 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00090 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002737 280.0
TLS3_k127_253562_2 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000004054 260.0
TLS3_k127_253562_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.000000000000005703 79.0
TLS3_k127_2584257_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 602.0
TLS3_k127_2584257_1 Cytochrome C oxidase subunit II, periplasmic domain K02275 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.0000000000000000000000000000000000000000000000003356 186.0
TLS3_k127_2584257_2 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02351,K07245 - - 0.000000000000000000000000000000000000000000005969 181.0
TLS3_k127_2584257_3 phosphoglycerate mutase - - - 0.00000000000000000002323 97.0
TLS3_k127_2584257_4 Cytochrome c oxidase subunit III K02276,K02299 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 0.000002557 51.0
TLS3_k127_2615394_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 1.301e-260 831.0
TLS3_k127_2615394_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009307 526.0
TLS3_k127_2615394_10 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000002981 211.0
TLS3_k127_2615394_11 Nucleotidyl transferase K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000004996 183.0
TLS3_k127_2615394_12 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000001517 183.0
TLS3_k127_2615394_13 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000001263 175.0
TLS3_k127_2615394_14 ASCH - - - 0.0000000000000000000000000000000000002044 151.0
TLS3_k127_2615394_15 HAD-hyrolase-like - - - 0.000000000000000004603 93.0
TLS3_k127_2615394_16 PIN domain K07063 - - 0.000000008372 63.0
TLS3_k127_2615394_2 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 504.0
TLS3_k127_2615394_3 alcohol dehydrogenase (NAD) activity K00001,K00121,K02267,K13980,K18857 GO:0000302,GO:0001101,GO:0001666,GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009410,GO:0009413,GO:0009414,GO:0009415,GO:0009628,GO:0009636,GO:0009651,GO:0009719,GO:0009725,GO:0009737,GO:0009743,GO:0009744,GO:0010033,GO:0010035,GO:0010038,GO:0010243,GO:0014070,GO:0014074,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0031000,GO:0032355,GO:0033993,GO:0034285,GO:0036270,GO:0036293,GO:0042221,GO:0042493,GO:0042542,GO:0042802,GO:0042803,GO:0043279,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046686,GO:0046983,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0055114,GO:0065007,GO:0070482,GO:0071944,GO:0080134,GO:0080135,GO:0097305,GO:1900037,GO:1900039,GO:1901698,GO:1901700 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 460.0
TLS3_k127_2615394_4 antibiotic catabolic process K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007517 431.0
TLS3_k127_2615394_5 PFAM ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 415.0
TLS3_k127_2615394_6 Melibiase K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 314.0
TLS3_k127_2615394_7 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003251 288.0
TLS3_k127_2615394_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003715 289.0
TLS3_k127_2615394_9 Fumarylacetoacetate (FAA) hydrolase family K05921 - 4.1.1.68 0.0000000000000000000000000000000000000000000000000000000000001547 221.0
TLS3_k127_2620725_0 Domain of unknown function (DUF3459) K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 562.0
TLS3_k127_2620725_1 MgtC family K07507 - - 0.00000000000000000001284 100.0
TLS3_k127_2634111_0 Alkanesulfonate monooxygenase K04091 - 1.14.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 486.0
TLS3_k127_2634111_1 Aminotransferase class-V K00830,K00839 GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 421.0
TLS3_k127_2634111_2 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008088 374.0
TLS3_k127_2634111_3 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 323.0
TLS3_k127_2634111_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000001879 171.0
TLS3_k127_2634111_5 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000144 126.0
TLS3_k127_26461_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005443 256.0
TLS3_k127_26461_1 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000002437 238.0
TLS3_k127_26461_2 PFAM LemA - - - 0.000000000000000000000000000000000000000000000000000000000006613 213.0
TLS3_k127_26461_3 PFAM S23 ribosomal protein - - - 0.00000000000000000000000000004102 122.0
TLS3_k127_2679992_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 392.0
TLS3_k127_2679992_1 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004102 243.0
TLS3_k127_2679992_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000002829 152.0
TLS3_k127_2683329_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 332.0
TLS3_k127_2683329_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000004623 190.0
TLS3_k127_2702181_0 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 418.0
TLS3_k127_2702181_1 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 419.0
TLS3_k127_2702181_10 protoporphyrinogen oxidase activity K00231 - 1.3.3.15,1.3.3.4 0.00000000000000003127 94.0
TLS3_k127_2702181_11 helix_turn_helix, Lux Regulon - - - 0.0000000000005771 73.0
TLS3_k127_2702181_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 406.0
TLS3_k127_2702181_3 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 399.0
TLS3_k127_2702181_4 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 293.0
TLS3_k127_2702181_5 UbiA prenyltransferase family K02548 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000002232 254.0
TLS3_k127_2702181_6 catechol 2,3-dioxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000005184 208.0
TLS3_k127_2702181_7 Dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000007266 178.0
TLS3_k127_2702181_8 O-methyltransferase - - - 0.0000000000000000000000000000000000000004859 162.0
TLS3_k127_2702181_9 carboxylic ester hydrolase activity - - - 0.000000000000000000000368 106.0
TLS3_k127_2704770_0 PFAM sodium calcium exchanger membrane region K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 417.0
TLS3_k127_2704770_1 Thiolase, C-terminal domain K00626 GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 355.0
TLS3_k127_2704770_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000007825 92.0
TLS3_k127_2704770_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 320.0
TLS3_k127_2704770_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000009079 214.0
TLS3_k127_2704770_4 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000345 180.0
TLS3_k127_2704770_5 phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000006741 150.0
TLS3_k127_2704770_6 SCO1 SenC K07152 - - 0.0000000000000000000000000000000002093 140.0
TLS3_k127_2704770_7 - - - - 0.0000000000000000000000000000003232 125.0
TLS3_k127_2704770_8 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000000002426 126.0
TLS3_k127_2704770_9 Protein of unknown function (DUF3237) - - - 0.000000000000000000000000000004799 124.0
TLS3_k127_271754_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 394.0
TLS3_k127_271754_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 383.0
TLS3_k127_271754_10 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000008651 113.0
TLS3_k127_271754_11 Bacterial PH domain - - - 0.000000000000003496 88.0
TLS3_k127_271754_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 291.0
TLS3_k127_271754_3 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 291.0
TLS3_k127_271754_4 ABC transporter K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000003299 262.0
TLS3_k127_271754_5 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006874 255.0
TLS3_k127_271754_6 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000307 229.0
TLS3_k127_271754_7 PFAM binding-protein-dependent transport systems inner membrane component K02017,K02018 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000009331 225.0
TLS3_k127_271754_8 PFAM luciferase-like - - - 0.000000000000000000000000000000000000000000000000000000000004237 221.0
TLS3_k127_271754_9 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000002169 190.0
TLS3_k127_2743772_0 ERAP1-like C-terminal domain K01256,K08776 - 3.4.11.2 1.786e-202 641.0
TLS3_k127_2743772_1 - - - - 0.00000000000000000000002561 108.0
TLS3_k127_2743772_2 - - - - 0.000000000000000000001549 101.0
TLS3_k127_2764797_0 Dak1_2 K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000165 286.0
TLS3_k127_2764797_1 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000005113 218.0
TLS3_k127_2764797_2 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000002048 86.0
TLS3_k127_2764797_3 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000549 65.0
TLS3_k127_2764797_4 carboxylic ester hydrolase activity - - - 0.00001405 48.0
TLS3_k127_2804255_0 tryptophan synthase activity K01696,K06001 - 4.2.1.20 3.652e-207 655.0
TLS3_k127_2804255_1 tryptophan synthase activity K01694,K01695,K01696,K10882,K13222 GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009606,GO:0009607,GO:0009617,GO:0009628,GO:0009629,GO:0009630,GO:0009651,GO:0009683,GO:0009684,GO:0009719,GO:0009725,GO:0009735,GO:0009850,GO:0009851,GO:0009941,GO:0009987,GO:0010033,GO:0010817,GO:0016020,GO:0016043,GO:0016053,GO:0016829,GO:0016830,GO:0016832,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0019904,GO:0031967,GO:0031975,GO:0032787,GO:0033036,GO:0033037,GO:0033554,GO:0033984,GO:0034641,GO:0034754,GO:0042221,GO:0042401,GO:0042430,GO:0042435,GO:0042445,GO:0042446,GO:0042545,GO:0042742,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045229,GO:0046219,GO:0046394,GO:0046483,GO:0050896,GO:0051179,GO:0051641,GO:0051704,GO:0051707,GO:0051716,GO:0052386,GO:0052482,GO:0052542,GO:0052543,GO:0052544,GO:0052545,GO:0065007,GO:0065008,GO:0070727,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0098542,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.2.8,4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 583.0
TLS3_k127_2804255_10 Kdo2-lipid A biosynthetic process K02517,K22311 - 2.3.1.241,2.3.1.265 0.00000000000000000000000000000000000000000000003699 181.0
TLS3_k127_2804255_11 PFAM TENA THI-4 protein Coenzyme PQQ biosynthesis protein C K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000004768 177.0
TLS3_k127_2804255_12 phosphoribosylanthranilate isomerase activity K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000009361 178.0
TLS3_k127_2804255_13 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000003227 180.0
TLS3_k127_2804255_14 ribonuclease activity - - - 0.000000000000000000000000000000000001782 142.0
TLS3_k127_2804255_15 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091,K06019 - 3.1.3.18,3.6.1.1 0.0000000000000000000000002092 115.0
TLS3_k127_2804255_16 Bacterial lipid A biosynthesis acyltransferase K02517,K22311 - 2.3.1.241,2.3.1.265 0.00000000000000000000001067 111.0
TLS3_k127_2804255_17 Protein of unknown function (DUF3995) - - - 0.0000000000000000006917 94.0
TLS3_k127_2804255_18 decarboxylase K01607 - 4.1.1.44 0.000000000000000006265 94.0
TLS3_k127_2804255_19 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K00999 GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.11,2.7.8.5 0.000000000004938 72.0
TLS3_k127_2804255_2 Anthranilate synthase component K01657 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 559.0
TLS3_k127_2804255_20 metal-dependent membrane protease K07052 - - 0.00000000001915 74.0
TLS3_k127_2804255_21 toxin-antitoxin pair type II binding - - - 0.0002392 48.0
TLS3_k127_2804255_3 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 329.0
TLS3_k127_2804255_4 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 324.0
TLS3_k127_2804255_5 Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities K01656,K13501 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0004425,GO:0004640,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016832,GO:0016833,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0033984,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.1.48,4.1.3.27,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 319.0
TLS3_k127_2804255_6 Tryptophanyl-tRNA synthetase K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 300.0
TLS3_k127_2804255_7 Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities K01656,K13501 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0004425,GO:0004640,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016832,GO:0016833,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0033984,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.1.48,4.1.3.27,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001132 274.0
TLS3_k127_2804255_8 Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities K01656,K13501 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0004425,GO:0004640,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016832,GO:0016833,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0033984,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.1.48,4.1.3.27,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000001048 261.0
TLS3_k127_2804255_9 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000436 182.0
TLS3_k127_2816048_0 ABC-type polar amino acid transport system, ATPase component K09972,K10004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 375.0
TLS3_k127_2816048_1 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K09970 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 299.0
TLS3_k127_2816048_2 Binding-protein-dependent transport system inner membrane component K09971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001801 287.0
TLS3_k127_2816048_3 beta-lactamase K17836 - 3.5.2.6 0.0002771 51.0
TLS3_k127_2826468_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 342.0
TLS3_k127_2826468_1 enoyl-CoA hydratase isomerase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 331.0
TLS3_k127_2826468_2 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000003102 271.0
TLS3_k127_2826468_3 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000001246 225.0
TLS3_k127_2826468_4 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000001921 214.0
TLS3_k127_2826468_5 Divergent 4Fe-4S mono-cluster - - - 0.000000000000000000000000000000000000000000002093 168.0
TLS3_k127_2826468_6 Belongs to the ABC transporter superfamily K02052,K02062 - - 0.0000000000000000000000000000000000000000001006 167.0
TLS3_k127_2826468_7 Acetyltransferase - - - 0.000000000000000000000000000000000003666 143.0
TLS3_k127_2826468_8 thiolester hydrolase activity K06889 - - 0.000000000001244 77.0
TLS3_k127_2870322_0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009345 391.0
TLS3_k127_2870322_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000004146 225.0
TLS3_k127_2870322_2 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000000000000000000000000000000005301 227.0
TLS3_k127_2870322_3 Uncharacterized protein conserved in bacteria (DUF2332) - - - 0.0000000000000000000000000000000000000000000000000000000000002893 226.0
TLS3_k127_2870322_4 FMN binding - - - 0.00000000000000000001417 102.0
TLS3_k127_2870322_5 - - - - 0.000000000000001345 91.0
TLS3_k127_2870322_6 Membrane protein involved in the export of o-antigen and teichoic acid K03328 - - 0.0000000003854 72.0
TLS3_k127_2879368_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 345.0
TLS3_k127_2879368_1 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 340.0
TLS3_k127_2898988_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 327.0
TLS3_k127_2898988_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 332.0
TLS3_k127_2898988_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000001836 223.0
TLS3_k127_2901566_0 UvrD/REP helicase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 534.0
TLS3_k127_2901566_1 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000005965 201.0
TLS3_k127_2918239_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 370.0
TLS3_k127_2918239_1 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 347.0
TLS3_k127_2918239_2 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 312.0
TLS3_k127_2918239_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 304.0
TLS3_k127_2918239_4 phosphate K02040 GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009742 271.0
TLS3_k127_2918239_5 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001553 259.0
TLS3_k127_2918239_6 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002452 253.0
TLS3_k127_2918239_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000001024 240.0
TLS3_k127_2918239_8 Hep Hag repeat protein - - - 0.0000000000000000000000000009656 126.0
TLS3_k127_2932472_0 COG0467 RecA-superfamily ATPases implicated in signal K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 539.0
TLS3_k127_2932472_1 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 366.0
TLS3_k127_2932472_2 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000008364 170.0
TLS3_k127_2932472_3 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000001947 169.0
TLS3_k127_2968485_0 MMPL family K06994 - - 3.262e-291 911.0
TLS3_k127_2968485_1 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 454.0
TLS3_k127_2968485_2 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 451.0
TLS3_k127_2968485_3 transcriptional regulator - - - 0.000000000000000000000000000000000000000001224 165.0
TLS3_k127_2968485_4 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000004098 141.0
TLS3_k127_2968485_5 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000007004 124.0
TLS3_k127_2968485_6 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000002816 67.0
TLS3_k127_2988297_0 protein-containing complex disassembly K02837,K07133 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 7.366e-203 644.0
TLS3_k127_2988297_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 426.0
TLS3_k127_2988297_10 phosphinothricin N-acetyltransferase activity K03823 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 2.3.1.183 0.0000000000000000000000000000000000537 141.0
TLS3_k127_2988297_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000004296 102.0
TLS3_k127_2988297_12 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000004797 58.0
TLS3_k127_2988297_13 Binds directly to 16S ribosomal RNA K02968 - - 0.00000005012 58.0
TLS3_k127_2988297_14 Short-chain dehydrogenase reductase sdr - - - 0.0001316 52.0
TLS3_k127_2988297_2 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 359.0
TLS3_k127_2988297_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00018 - 1.1.1.26,1.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 348.0
TLS3_k127_2988297_4 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 291.0
TLS3_k127_2988297_5 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000002083 213.0
TLS3_k127_2988297_6 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000001937 201.0
TLS3_k127_2988297_7 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000006011 199.0
TLS3_k127_2988297_8 short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000005408 163.0
TLS3_k127_2988297_9 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000002603 147.0
TLS3_k127_2996103_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000002806 198.0
TLS3_k127_2996103_1 Cysteine-rich domain K18928 - - 0.00000000000000000000000000000000000000001115 175.0
TLS3_k127_2996103_2 Iron-sulfur cluster-binding protein K18929 - - 0.00000000000000000000000002547 117.0
TLS3_k127_2996103_3 DinB family - - - 0.000000000000005965 81.0
TLS3_k127_2996103_4 Histidine kinase K02491 - 2.7.13.3 0.0000000000115 79.0
TLS3_k127_3008036_0 PFAM sodium calcium exchanger membrane region K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 408.0
TLS3_k127_3008036_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000021 236.0
TLS3_k127_3008036_2 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000001885 185.0
TLS3_k127_3008036_3 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000007291 188.0
TLS3_k127_3008036_4 PFAM Exonuclease RNase T and DNA polymerase III K02342 - 2.7.7.7 0.0000000000000001997 89.0
TLS3_k127_3008036_5 Antibiotic biosynthesis monooxygenase - - - 0.0000000000001447 75.0
TLS3_k127_3026700_0 ATPase AAA-2 domain protein K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 432.0
TLS3_k127_3026700_1 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 434.0
TLS3_k127_3026700_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 405.0
TLS3_k127_3026700_3 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 369.0
TLS3_k127_3026700_4 PFAM RNA binding S1 domain protein K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 355.0
TLS3_k127_3026700_5 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000008203 232.0
TLS3_k127_3026700_6 - - - - 0.00006371 46.0
TLS3_k127_314970_0 Alpha beta hydrolase K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 344.0
TLS3_k127_314970_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000006125 222.0
TLS3_k127_314970_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000106 183.0
TLS3_k127_314970_3 HDOD domain - - - 0.0000000000000000000000000000000000000007565 157.0
TLS3_k127_314970_4 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000001725 86.0
TLS3_k127_3198731_0 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 553.0
TLS3_k127_3216600_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 511.0
TLS3_k127_3216600_1 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 332.0
TLS3_k127_3216600_10 Winged helix-turn-helix DNA-binding - - - 0.000000000000007706 83.0
TLS3_k127_3216600_11 LysM domain K12204 - - 0.00000000008796 76.0
TLS3_k127_3216600_12 Flavin reductase - - - 0.0000001463 60.0
TLS3_k127_3216600_13 Bacterial SH3 domain - - - 0.0001917 53.0
TLS3_k127_3216600_2 Domain of unknown function (DUF3524) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001754 290.0
TLS3_k127_3216600_3 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000001018 235.0
TLS3_k127_3216600_4 PFAM ADP-ribosylation Crystallin J1 - - - 0.0000000000000000000000000000000000000000000000000000005288 205.0
TLS3_k127_3216600_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000001709 189.0
TLS3_k127_3216600_6 feS assembly protein SufB K07033,K09014 - - 0.000000000000000000000000000000000000000005533 158.0
TLS3_k127_3216600_7 NUDIX domain - - - 0.00000000000000000000000000000006967 136.0
TLS3_k127_3216600_8 Virulence factor BrkB K07058 - - 0.000000000000000000000001372 115.0
TLS3_k127_3216600_9 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000002298 99.0
TLS3_k127_330449_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 452.0
TLS3_k127_330449_1 general stress protein - - - 0.0000000003086 67.0
TLS3_k127_3328030_0 Belongs to the glycosyl hydrolase 18 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 328.0
TLS3_k127_3328030_1 Single Cache domain 2 K02660,K03406,K05875,K05876,K07216,K11525 - - 0.00000000000000000000000000000000003406 153.0
TLS3_k127_3332557_0 Conserved carboxylase K01571 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 541.0
TLS3_k127_3332557_1 homoserine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 522.0
TLS3_k127_3332557_10 protein with SCP PR1 domains - - - 0.0000000000000000000000000008032 126.0
TLS3_k127_3332557_11 methyltransferase - - - 0.000000000000000001102 93.0
TLS3_k127_3332557_12 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000001825 88.0
TLS3_k127_3332557_13 PFAM biotin lipoyl attachment domain-containing protein - - - 0.000000000000006162 81.0
TLS3_k127_3332557_14 transcriptional regulator - - - 0.0000000004182 68.0
TLS3_k127_3332557_15 response regulator, receiver K08087,K11527 - 2.7.13.3 0.000000004374 70.0
TLS3_k127_3332557_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 514.0
TLS3_k127_3332557_3 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001192 255.0
TLS3_k127_3332557_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001664 253.0
TLS3_k127_3332557_5 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000001567 164.0
TLS3_k127_3332557_6 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000002251 144.0
TLS3_k127_3332557_7 GrpB protein - - - 0.0000000000000000000000000000004832 136.0
TLS3_k127_3332557_8 GrpB protein - - - 0.00000000000000000000000000002475 130.0
TLS3_k127_3332557_9 PEP-utilising enzyme, mobile domain - - - 0.0000000000000000000000000001408 129.0
TLS3_k127_3342842_0 Amidohydrolase family K01461,K06015 - 3.5.1.81,3.5.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007451 578.0
TLS3_k127_3342842_1 PFAM SPFH domain Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 373.0
TLS3_k127_3342842_2 PFAM Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 308.0
TLS3_k127_3342842_3 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000745 230.0
TLS3_k127_3342842_4 Superfamily I DNA and RNA helicases and helicase subunits - - - 0.0000000000000000000000000000000000000000000000000000000005071 229.0
TLS3_k127_3342842_5 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000003592 136.0
TLS3_k127_3342842_6 response regulator - - - 0.0000000000000000005004 89.0
TLS3_k127_3342842_7 PFAM Uncharacterised protein family UPF0150 K18843 - - 0.00000000000000001051 87.0
TLS3_k127_3342842_8 Mycolic acid cyclopropane synthetase - - - 0.0000000003909 69.0
TLS3_k127_3392659_0 PFAM peptidase C60 sortase A and B - - - 0.00000000000001141 83.0
TLS3_k127_3392659_1 Sortase (surface protein transpeptidase) - - - 0.00000000000004083 81.0
TLS3_k127_3392659_2 Domain of unknown function (DUF4115) - - - 0.000000000002597 79.0
TLS3_k127_3392659_3 CARDB - - - 0.00000133 59.0
TLS3_k127_3413846_0 PFAM FAD linked oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000778 445.0
TLS3_k127_3413846_1 sirohydrochlorin cobaltochelatase activity K03794,K03795,K06042 - 4.99.1.3,4.99.1.4,5.4.99.60,5.4.99.61 0.000000000000000000000000000000001757 138.0
TLS3_k127_3413846_2 Putative regulatory protein - - - 0.000001698 59.0
TLS3_k127_3419840_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 302.0
TLS3_k127_3419840_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002165 286.0
TLS3_k127_3419840_2 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000117 274.0
TLS3_k127_3419840_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000015 200.0
TLS3_k127_3419840_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000003708 81.0
TLS3_k127_3461485_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 5.594e-233 740.0
TLS3_k127_3461485_1 TIGRFAM RNA polymerase sigma factor, FliA WhiG K02405 - - 0.000000000000000000000000000000000000000000000000001714 191.0
TLS3_k127_3461485_2 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000000000000000000000000000000000000000000003764 189.0
TLS3_k127_3461485_3 Flagellar protein YcgR - - - 0.0000000001779 70.0
TLS3_k127_3461485_4 flagellar K02404 - - 0.00000007363 64.0
TLS3_k127_3461485_5 Flagellar basal body rod FlgEFG protein C-terminal K02392 - - 0.000001268 55.0
TLS3_k127_3472969_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 421.0
TLS3_k127_3472969_1 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000003041 245.0
TLS3_k127_3472969_2 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000858 184.0
TLS3_k127_3472969_3 Putative heavy-metal-binding - - - 0.00000000000000000000000000000004647 128.0
TLS3_k127_347821_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006153 261.0
TLS3_k127_347821_1 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000001733 205.0
TLS3_k127_347821_2 water channel activity K02440,K06188 - - 0.000000000000000000000000000000000000000000000000000006276 197.0
TLS3_k127_347821_3 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000001031 160.0
TLS3_k127_347821_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000001414 118.0
TLS3_k127_347821_5 DinB family - - - 0.0000000000001536 76.0
TLS3_k127_347821_6 gluconolactonase activity K14274,K20276 - - 0.00001253 57.0
TLS3_k127_3507730_0 Daunorubicin resistance ABC transporter ATP-binding subunit K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 307.0
TLS3_k127_3507730_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000007576 189.0
TLS3_k127_3507730_2 Sulfite exporter TauE/SafE - - - 0.00000000000000004143 90.0
TLS3_k127_3507730_3 Cupin 2, conserved barrel domain protein K18991 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - 0.000000002553 63.0
TLS3_k127_352963_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 1.755e-271 859.0
TLS3_k127_352963_1 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 476.0
TLS3_k127_352963_10 hydrolase K07025 - - 0.0004248 49.0
TLS3_k127_352963_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 386.0
TLS3_k127_352963_3 MazG nucleotide pyrophosphohydrolase domain K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 377.0
TLS3_k127_352963_4 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 289.0
TLS3_k127_352963_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000007019 216.0
TLS3_k127_352963_6 phosphatase activity - - - 0.00000000000000000000007857 108.0
TLS3_k127_352963_7 Pfam:Pyridox_oxidase - - - 0.00000000000000000006699 96.0
TLS3_k127_352963_8 Thioredoxin - - - 0.000000000000002618 85.0
TLS3_k127_352963_9 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000009232 81.0
TLS3_k127_3531704_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 620.0
TLS3_k127_3531704_1 flavoprotein involved in K transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 455.0
TLS3_k127_3531704_10 GTP binding - - - 0.000000000000000000000000000000000000000000000001403 182.0
TLS3_k127_3531704_11 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000002088 141.0
TLS3_k127_3531704_12 - - - - 0.0000000000000000000000000003242 124.0
TLS3_k127_3531704_13 YjbR - - - 0.0000000000000000000000432 104.0
TLS3_k127_3531704_14 PFAM NUDIX hydrolase - - - 0.000000000000000000003969 98.0
TLS3_k127_3531704_15 Pyridoxamine 5'-phosphate - - - 0.000000000000183 77.0
TLS3_k127_3531704_16 PFAM LysM domain - - - 0.000267 51.0
TLS3_k127_3531704_2 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 329.0
TLS3_k127_3531704_3 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 321.0
TLS3_k127_3531704_4 Pfam Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 301.0
TLS3_k127_3531704_5 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002592 265.0
TLS3_k127_3531704_6 Belongs to the peptidase S1B family - - - 0.00000000000000000000000000000000000000000000000000000000316 212.0
TLS3_k127_3531704_7 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000003825 203.0
TLS3_k127_3531704_8 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000007361 197.0
TLS3_k127_3531704_9 FMN-dependent dehydrogenase K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000002908 192.0
TLS3_k127_3540994_0 PFAM Acetyl-CoA hydrolase transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001622 287.0
TLS3_k127_3540994_1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003128 250.0
TLS3_k127_3540994_2 Histidine kinase K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000001395 257.0
TLS3_k127_3540994_3 Luciferase-like monooxygenase - - - 0.000000000000000000002517 100.0
TLS3_k127_3563538_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002649 292.0
TLS3_k127_3563538_1 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000002886 174.0
TLS3_k127_3563538_2 -O-antigen K02847,K02849,K21003 - - 0.0000000000000000000128 106.0
TLS3_k127_3563538_3 COG0489 ATPases involved in chromosome partitioning - - - 0.00000000000000001371 91.0
TLS3_k127_3563538_4 extracellular polysaccharide biosynthetic process K07011,K07184 - - 0.00000005813 64.0
TLS3_k127_3601933_0 Zn-dependent alcohol dehydrogenases K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005159 414.0
TLS3_k127_3601933_1 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 394.0
TLS3_k127_3601933_2 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000009715 73.0
TLS3_k127_3629835_0 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 287.0
TLS3_k127_3629835_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000007454 169.0
TLS3_k127_3629835_2 - - - - 0.000000000000000000000000000000000000003992 157.0
TLS3_k127_3629835_3 helix_turn_helix, Lux Regulon - - - 0.00000004669 66.0
TLS3_k127_3638621_0 Belongs to the pirin family K06911 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006881 267.0
TLS3_k127_3638621_1 Pfam:DUF385 - - - 0.0000000000000000000000000000000000000000000003981 174.0
TLS3_k127_3638621_2 transcriptional regulator (MarR - - - 0.000000000000000000000000000000001449 136.0
TLS3_k127_3665362_0 flavoprotein involved in K transport K03379 - 1.14.13.22 4.132e-262 819.0
TLS3_k127_3665362_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000003646 218.0
TLS3_k127_3665362_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000003843 134.0
TLS3_k127_3667341_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576 6.5.1.2 3.12e-199 649.0
TLS3_k127_3667341_1 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 412.0
TLS3_k127_3667341_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000001167 149.0
TLS3_k127_3667341_3 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000002019 125.0
TLS3_k127_3670067_0 2-hydroxyacyl-CoA lyase 1 K12261 GO:0001561,GO:0003674,GO:0003824,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015031,GO:0015833,GO:0016042,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0019395,GO:0019752,GO:0019842,GO:0022607,GO:0030258,GO:0030976,GO:0031907,GO:0031974,GO:0032787,GO:0033036,GO:0033365,GO:0034440,GO:0034613,GO:0036094,GO:0042579,GO:0042802,GO:0042886,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046907,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0051259,GO:0051641,GO:0051649,GO:0055114,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072329,GO:0072594,GO:0072662,GO:0072663,GO:0097159,GO:1901363,GO:1901575,GO:1901681 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 585.0
TLS3_k127_3670067_1 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 468.0
TLS3_k127_3670067_2 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 344.0
TLS3_k127_3670067_3 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 322.0
TLS3_k127_3670067_4 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002725 257.0
TLS3_k127_3670067_5 helix_turn_helix, Lux Regulon - - - 0.000000000000005032 83.0
TLS3_k127_3670844_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K11177 - 1.17.1.4 5.232e-270 852.0
TLS3_k127_3670844_1 oxidation-reduction process - - - 0.00000000000000000000000000000002015 132.0
TLS3_k127_3670844_2 ThiS family K03636 - - 0.000000000002088 70.0
TLS3_k127_3670844_3 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518,K07302,K13480 - 1.2.5.3,1.3.99.16 0.00000000001198 64.0
TLS3_k127_3702440_0 MMPL family K06994 - - 5.453e-217 696.0
TLS3_k127_3702440_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 601.0
TLS3_k127_3702440_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.00000000000000000000000000000008672 129.0
TLS3_k127_3702440_11 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000001188 128.0
TLS3_k127_3702440_12 Domain of unknown function (DUF4389) - - - 0.0000000000000000000000000001273 123.0
TLS3_k127_3702440_13 PFAM DSBA oxidoreductase - - - 0.00000000000000000000000000703 124.0
TLS3_k127_3702440_14 Major Facilitator Superfamily - - - 0.00000000000000000000000003847 122.0
TLS3_k127_3702440_15 PFAM SPFH domain Band 7 family - - - 0.0000000000000000000000006447 116.0
TLS3_k127_3702440_16 PFAM Bacterial regulatory protein, arsR family - - - 0.000000000000000000000006304 105.0
TLS3_k127_3702440_17 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000002978 101.0
TLS3_k127_3702440_18 Thioredoxin - - - 0.0000000000000001687 88.0
TLS3_k127_3702440_19 Pkd domain containing protein - - - 0.000005739 60.0
TLS3_k127_3702440_2 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 593.0
TLS3_k127_3702440_20 PD-(D/E)XK nuclease superfamily K07465 - - 0.00001716 56.0
TLS3_k127_3702440_3 PFAM FAD linked oxidase domain protein K00803 - 2.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 570.0
TLS3_k127_3702440_4 Carboxylesterase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 390.0
TLS3_k127_3702440_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 372.0
TLS3_k127_3702440_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 305.0
TLS3_k127_3702440_7 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001753 292.0
TLS3_k127_3702440_8 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000253 148.0
TLS3_k127_3702440_9 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000001044 135.0
TLS3_k127_3720570_0 phosphatidylinositol kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001409 234.0
TLS3_k127_3720570_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000003205 201.0
TLS3_k127_3720570_2 phenazine biosynthesis protein PhzF family K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000001769 182.0
TLS3_k127_3748758_0 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 304.0
TLS3_k127_3748758_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003829 254.0
TLS3_k127_3748758_10 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000002003 100.0
TLS3_k127_3748758_11 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000001023 89.0
TLS3_k127_3748758_12 DNA repair exonuclease - - - 0.00000000000000002434 92.0
TLS3_k127_3748758_13 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000006298 84.0
TLS3_k127_3748758_15 COG3209 Rhs family protein - - - 0.00000006502 64.0
TLS3_k127_3748758_16 - - - - 0.0000001829 62.0
TLS3_k127_3748758_17 Muconolactone delta-isomerase K03464 - 5.3.3.4 0.0001851 48.0
TLS3_k127_3748758_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000001958 221.0
TLS3_k127_3748758_3 Dehydrogenase - - - 0.0000000000000000000000000000000000000000003839 168.0
TLS3_k127_3748758_4 Type III restriction enzyme res subunit K01156 - 3.1.21.5 0.00000000000000000000000000000000000000006658 171.0
TLS3_k127_3748758_5 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000003104 141.0
TLS3_k127_3748758_6 Aminoacyl-tRNA editing domain K03976 - - 0.00000000000000000000000000000000102 142.0
TLS3_k127_3748758_7 KR domain K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000002884 134.0
TLS3_k127_3748758_8 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family K16048 - - 0.000000000000000000000000000001272 129.0
TLS3_k127_3748758_9 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000001934 124.0
TLS3_k127_3753098_0 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000003628 166.0
TLS3_k127_3753098_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000007592 148.0
TLS3_k127_3753098_2 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.000000000000000007384 90.0
TLS3_k127_3753098_3 family 18 - - - 0.0000000002096 73.0
TLS3_k127_3764523_0 Belongs to the ClpA ClpB family K03696 - - 5.615e-304 953.0
TLS3_k127_3764523_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007567 319.0
TLS3_k127_3764523_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 313.0
TLS3_k127_3764523_3 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008079 283.0
TLS3_k127_3764523_4 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000252 176.0
TLS3_k127_3764523_5 PFAM MerR family regulatory protein K13640 - - 0.00000000000000000000000001495 112.0
TLS3_k127_3764523_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000001173 110.0
TLS3_k127_3764523_7 Trm112p-like protein - - - 0.000000000000000000000077 98.0
TLS3_k127_3764523_8 COGs COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.0000000000000000003199 90.0
TLS3_k127_3764523_9 Colicin V production protein K03558 - - 0.000000000000003023 83.0
TLS3_k127_3787606_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 1.809e-251 790.0
TLS3_k127_3787606_1 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 447.0
TLS3_k127_3787606_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 362.0
TLS3_k127_3787606_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 291.0
TLS3_k127_3787606_4 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006016 262.0
TLS3_k127_3787606_5 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000001913 196.0
TLS3_k127_3787606_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000007044 105.0
TLS3_k127_3787606_7 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.000000000000000000003949 97.0
TLS3_k127_3787606_8 Cytidylate kinase-like family - - - 0.0000000000000000001146 98.0
TLS3_k127_3787606_9 CBS domain - - - 0.0000000000000000004393 93.0
TLS3_k127_380405_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.653e-203 648.0
TLS3_k127_380405_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 5.698e-197 651.0
TLS3_k127_380405_10 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 363.0
TLS3_k127_380405_11 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 329.0
TLS3_k127_380405_12 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 302.0
TLS3_k127_380405_13 Inositol monophosphatase family K01092,K05602 - 3.1.3.15,3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000001318 245.0
TLS3_k127_380405_14 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177,K03483 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000002662 225.0
TLS3_k127_380405_15 Cupin domain - - - 0.000000000000000000000000000000000000000000000000001627 186.0
TLS3_k127_380405_16 methyltransferase K15471 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016741,GO:0022607,GO:0032259,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071770,GO:0071840,GO:0071944 - 0.00000000000000000000000000000000000000002996 161.0
TLS3_k127_380405_17 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000531 155.0
TLS3_k127_380405_18 RNHCP domain - - - 0.00000000000000000000000000000000000003511 145.0
TLS3_k127_380405_19 Small Multidrug Resistance protein K11741 - - 0.0000000000000000000000000000003227 136.0
TLS3_k127_380405_2 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 3.657e-194 623.0
TLS3_k127_380405_20 PFAM Acetyltransferase (GNAT) family - - - 0.000000000000000000000000009424 117.0
TLS3_k127_380405_21 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000008488 108.0
TLS3_k127_380405_22 Protein of unknown function (DUF448) K07742 - - 0.000000000000000000000003431 104.0
TLS3_k127_380405_23 selenium-dependent hydroxylase accessory protein YqeC - - - 0.00000000000000000000000356 112.0
TLS3_k127_380405_24 - - - - 0.00000000000000001043 85.0
TLS3_k127_380405_25 - - - - 0.000000000003405 71.0
TLS3_k127_380405_26 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000176 44.0
TLS3_k127_380405_27 SpoVT / AbrB like domain - - - 0.0003533 51.0
TLS3_k127_380405_3 PFAM aldo keto reductase K05882 - 1.1.1.91 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 469.0
TLS3_k127_380405_4 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 466.0
TLS3_k127_380405_5 Beta-eliminating lyase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 413.0
TLS3_k127_380405_6 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 413.0
TLS3_k127_380405_7 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 396.0
TLS3_k127_380405_8 PFAM Transketolase central region K00162,K11381,K21417 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 378.0
TLS3_k127_380405_9 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 365.0
TLS3_k127_3852733_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 408.0
TLS3_k127_3852733_1 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000003028 142.0
TLS3_k127_3852733_2 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000000019 139.0
TLS3_k127_3854252_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 474.0
TLS3_k127_3854252_1 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 367.0
TLS3_k127_3854252_10 TIGRFAM autotransporter-associated beta strand repeat protein - - - 0.00000000000000008774 90.0
TLS3_k127_3854252_11 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000003885 64.0
TLS3_k127_3854252_12 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000002341 59.0
TLS3_k127_3854252_2 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 299.0
TLS3_k127_3854252_3 TIGRFAM serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000179 245.0
TLS3_k127_3854252_4 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000002017 236.0
TLS3_k127_3854252_5 - - - - 0.000000000000000000000000000000000000000000000000000002787 202.0
TLS3_k127_3854252_6 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000001343 173.0
TLS3_k127_3854252_7 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000209 168.0
TLS3_k127_3854252_8 Methylmuconolactone methyl-isomerase - - - 0.0000000000000000000000000000000000001315 145.0
TLS3_k127_3854252_9 Ferredoxin - - - 0.0000000000000000000000000122 115.0
TLS3_k127_386085_0 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 309.0
TLS3_k127_386085_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002489 285.0
TLS3_k127_386085_2 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001653 232.0
TLS3_k127_3908926_0 Binding-protein-dependent transport systems inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 466.0
TLS3_k127_3908926_1 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 368.0
TLS3_k127_3908926_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 313.0
TLS3_k127_3908926_3 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000005166 211.0
TLS3_k127_3908926_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000001051 163.0
TLS3_k127_3908926_5 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000004544 140.0
TLS3_k127_3908926_6 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000001655 125.0
TLS3_k127_3908926_7 - - - - 0.00000003739 59.0
TLS3_k127_3929071_0 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002144 276.0
TLS3_k127_3929071_1 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000000000000000000000000000000000000000003988 240.0
TLS3_k127_3929071_2 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000000000000000558 181.0
TLS3_k127_3929071_3 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000004387 148.0
TLS3_k127_3929071_4 Helix-turn-helix diphteria tox regulatory element K03709 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000007491 116.0
TLS3_k127_3930447_0 Phage portal protein, SPP1 Gp6-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 446.0
TLS3_k127_3930447_1 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 376.0
TLS3_k127_3930447_10 - - - - 0.00000000000000000000005749 102.0
TLS3_k127_3930447_11 Large-conductance mechanosensitive channel, MscL K03282 - - 0.0000000000000002313 85.0
TLS3_k127_3930447_12 chemotaxis K03406 - - 0.00002192 53.0
TLS3_k127_3930447_2 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003166 263.0
TLS3_k127_3930447_3 Subtilase family - - - 0.00000000000000000000000000000000000000000000000006049 201.0
TLS3_k127_3930447_4 transcriptional regulator K07734 - - 0.000000000000000000000000000000000000000000000002551 185.0
TLS3_k127_3930447_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000001945 149.0
TLS3_k127_3930447_6 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) K08680 - 4.2.99.20 0.0000000000000000000000000000000004182 151.0
TLS3_k127_3930447_7 CHRD domain - - - 0.0000000000000000000000000000006644 128.0
TLS3_k127_3930447_8 ARD/ARD' family - - - 0.000000000000000000000000000006006 123.0
TLS3_k127_3930447_9 Transglycosylase associated protein - - - 0.00000000000000000000000001446 111.0
TLS3_k127_393163_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1025.0
TLS3_k127_393163_1 MgtC family K07507 - - 0.00000000000000000000008663 104.0
TLS3_k127_393163_2 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000005444 78.0
TLS3_k127_3948997_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 440.0
TLS3_k127_3948997_1 Predicted membrane protein (DUF2254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 374.0
TLS3_k127_3948997_2 ig-like, plexins, transcription factors - - - 0.0000000000000000000000000000000000000000000000000000000000001713 228.0
TLS3_k127_3948997_3 - - - - 0.000000000000000000000000000000000000000000000000000000004775 209.0
TLS3_k127_3948997_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000001503 157.0
TLS3_k127_3950426_0 Phage tail sheath C-terminal domain K06907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000803 574.0
TLS3_k127_3950426_1 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 462.0
TLS3_k127_3950426_2 - - - - 0.000000000000000000000000000000000000000002842 159.0
TLS3_k127_3950426_3 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000004255 158.0
TLS3_k127_3950426_4 AAA ATPase containing von Willebrand factor type A (vWA) domain - - - 0.0000000000000000000000000000000000009717 151.0
TLS3_k127_3950426_5 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000001337 137.0
TLS3_k127_3950426_6 Protein of unknown function (DUF4255) - - - 0.0000000000000000000000000000000336 136.0
TLS3_k127_3950426_7 Bacterial Ig-like domain (group 3) - - - 0.0000000000000000000000000000002077 144.0
TLS3_k127_3950426_8 - - - - 0.000000000000005612 76.0
TLS3_k127_3950426_9 histone H2A K63-linked ubiquitination - - - 0.000000001277 72.0
TLS3_k127_3959351_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 302.0
TLS3_k127_3959351_1 PAC2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002086 244.0
TLS3_k127_3959351_2 Polysaccharide deacetylase - GO:0005575,GO:0016020 - 0.0000000000000000000000000001592 126.0
TLS3_k127_3959351_3 Helix-turn-helix domain - - - 0.000000000000000009027 91.0
TLS3_k127_3970934_0 Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 296.0
TLS3_k127_3970934_1 Methyltransferase, chemotaxis proteins K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000228 310.0
TLS3_k127_3970934_2 Sterol carrier protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 297.0
TLS3_k127_3970934_3 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001207 269.0
TLS3_k127_3970934_4 iron-sulfur cluster biosynthesis transcriptional regulator SufR K09012 - - 0.00000000000000000003119 100.0
TLS3_k127_3970934_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000001155 56.0
TLS3_k127_3982260_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008378 560.0
TLS3_k127_3982260_1 Radical SAM domain protein K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 473.0
TLS3_k127_3982260_10 YqcI/YcgG family K09190 - - 0.00000000000000000000000000000000000000000000000000000000000000000004817 240.0
TLS3_k127_3982260_11 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000003861 233.0
TLS3_k127_3982260_12 - - - - 0.000000000000000000000000000000000000000000000000001335 200.0
TLS3_k127_3982260_13 methyltransferase - - - 0.00000000000000000000000000000000000000000000001721 182.0
TLS3_k127_3982260_14 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000000008937 163.0
TLS3_k127_3982260_15 Two component regulator propeller - - - 0.000000000000000000000000000003181 133.0
TLS3_k127_3982260_16 PFAM pyridoxamine 5'-phosphate K07005 - - 0.0000000000000002207 85.0
TLS3_k127_3982260_17 metalloendoproteinase 1-like K01402 - 3.4.24.34 0.000000000008723 78.0
TLS3_k127_3982260_18 Preprotein translocase SecG subunit K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000006438 64.0
TLS3_k127_3982260_19 - - - - 0.000001368 59.0
TLS3_k127_3982260_2 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 377.0
TLS3_k127_3982260_20 Zinc-dependent metalloprotease K01388 - 3.4.24.7 0.00003723 56.0
TLS3_k127_3982260_3 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 371.0
TLS3_k127_3982260_4 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 335.0
TLS3_k127_3982260_5 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 310.0
TLS3_k127_3982260_6 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 297.0
TLS3_k127_3982260_7 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002049 281.0
TLS3_k127_3982260_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001997 289.0
TLS3_k127_3982260_9 Domain of unknown function (DUF1989) K09967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001246 249.0
TLS3_k127_3987022_0 cysteinyl-tRNA aminoacylation K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 509.0
TLS3_k127_3987022_1 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 376.0
TLS3_k127_3987022_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000003255 243.0
TLS3_k127_3987022_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000004059 164.0
TLS3_k127_3987022_4 cytochrome p450 K14370,K21113,K21114 GO:0000166,GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0009058,GO:0009987,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0019748,GO:0020037,GO:0030638,GO:0030639,GO:0033067,GO:0033068,GO:0036094,GO:0036199,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044282,GO:0044550,GO:0046164,GO:0046483,GO:0046906,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901334,GO:1901336,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1902652 1.14.13.154,1.14.15.8 0.00000000000000000000000000000000001907 142.0
TLS3_k127_3987022_5 Abc-2 type transporter K01992 - - 0.00000000000000000000000000000001794 136.0
TLS3_k127_3987022_6 MobA-like NTP transferase domain K07281 - 2.7.7.74 0.00000000000000001499 87.0
TLS3_k127_3987022_7 Glycosyl hydrolase family 92 - - - 0.0003345 53.0
TLS3_k127_4023154_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001313 251.0
TLS3_k127_4023154_1 PFAM Enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000011 163.0
TLS3_k127_4023154_2 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000007104 154.0
TLS3_k127_4069445_0 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 330.0
TLS3_k127_4069445_1 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000176 267.0
TLS3_k127_4069445_2 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000001817 217.0
TLS3_k127_4069445_3 3-demethylubiquinone-9 3-O-methyltransferase activity K15257 - - 0.00000000000000000000000000000000002256 151.0
TLS3_k127_4069445_4 converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.00000000000000000000000000002615 131.0
TLS3_k127_4069445_5 SnoaL-like domain - - - 0.000000000000121 76.0
TLS3_k127_4069445_6 protein possibly involved in aromatic compounds catabolism - - - 0.0000000000002967 76.0
TLS3_k127_4069445_7 SPTR D1C1B9 DinB family protein - - - 0.000000001067 66.0
TLS3_k127_4069445_8 - - - - 0.000000004104 62.0
TLS3_k127_4069445_9 PHP domain K04477 - - 0.0007936 44.0
TLS3_k127_4076871_0 Metallo-beta-lactamase superfamily K05555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 349.0
TLS3_k127_4076871_1 PFAM Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003867 277.0
TLS3_k127_4076871_2 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000005106 218.0
TLS3_k127_4076871_3 cytochrome complex assembly - GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 - 0.00000000000000000000000000000000000000000000000000001192 200.0
TLS3_k127_4142325_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 516.0
TLS3_k127_4142325_1 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 331.0
TLS3_k127_4142325_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 327.0
TLS3_k127_4142325_3 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 315.0
TLS3_k127_4142325_4 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 303.0
TLS3_k127_4142325_5 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000006481 240.0
TLS3_k127_4142325_6 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000004101 106.0
TLS3_k127_4142325_7 Thiol-activated cytolysin K11031 - - 0.000000000000002728 89.0
TLS3_k127_4142325_8 transcriptional regulator domain protein - - - 0.0000000000003481 78.0
TLS3_k127_4151226_0 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 450.0
TLS3_k127_4151226_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000007091 208.0
TLS3_k127_4151226_2 sugar-phosphate isomerases, RpiB LacA LacB family K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000001575 165.0
TLS3_k127_4151226_3 Belongs to the SUA5 family K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000000000000004173 141.0
TLS3_k127_4151226_4 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000002222 90.0
TLS3_k127_4154657_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000007358 186.0
TLS3_k127_4159579_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002174 270.0
TLS3_k127_4159579_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.0000000000000000000000000000000000000000000000002169 185.0
TLS3_k127_4159579_2 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.000000000000000000000000000000000000000002362 161.0
TLS3_k127_4159579_3 MaoC like domain - - - 0.00000000000000000000000000000000000002728 149.0
TLS3_k127_4159579_4 dehydratase - - - 0.000000000000000000000006148 103.0
TLS3_k127_4159579_5 - - - - 0.0000000002091 73.0
TLS3_k127_4159579_6 - - - - 0.0000000008476 71.0
TLS3_k127_4173988_0 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 345.0
TLS3_k127_4173988_1 Succinoglycan biosynthesis protein exoa - - - 0.000000000000000000000000000000000000000000000000000000000000006531 228.0
TLS3_k127_4173988_2 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000642 232.0
TLS3_k127_4173988_3 Lipid A core-O-antigen ligase-like enyme - - - 0.000000000000000000000000000002979 136.0
TLS3_k127_4173988_4 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.000000000004278 78.0
TLS3_k127_4173988_5 Glycosyl transferase 4-like - - - 0.00002631 56.0
TLS3_k127_4194732_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 373.0
TLS3_k127_4194732_1 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 308.0
TLS3_k127_4194732_2 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000001815 205.0
TLS3_k127_4194732_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0034214,GO:0042802,GO:0043170,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0061799,GO:0065003,GO:0071704,GO:0071840,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 0.000000000000000000000000000000000000000000000000000007379 198.0
TLS3_k127_4194732_4 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000009171 85.0
TLS3_k127_4194732_5 haloacid dehalogenase-like hydrolase - - - 0.00000000000001079 78.0
TLS3_k127_4207464_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 575.0
TLS3_k127_4207464_1 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000000000000000000001723 236.0
TLS3_k127_4218617_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 595.0
TLS3_k127_4218617_1 PFAM ABC transporter related K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 536.0
TLS3_k127_4218617_10 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000003796 126.0
TLS3_k127_4218617_11 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000000000000008961 113.0
TLS3_k127_4218617_12 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.0000000000000000000003365 112.0
TLS3_k127_4218617_13 Domain of unknown function (DUF1508) K09946 - - 0.00000004452 57.0
TLS3_k127_4218617_14 Beta-lactamase enzyme family K07258,K17836 - 3.4.16.4,3.5.2.6 0.0000004447 63.0
TLS3_k127_4218617_15 Thioesterase superfamily - - - 0.0006044 48.0
TLS3_k127_4218617_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 465.0
TLS3_k127_4218617_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 467.0
TLS3_k127_4218617_4 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 368.0
TLS3_k127_4218617_5 Fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001165 285.0
TLS3_k127_4218617_6 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000001124 269.0
TLS3_k127_4218617_7 Poly(3-hydroxybutyrate) depolymerase K03932 - - 0.000000000000000000000000000000000000000000001871 179.0
TLS3_k127_4218617_8 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000428 151.0
TLS3_k127_4218617_9 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000883 123.0
TLS3_k127_4224558_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.292e-196 629.0
TLS3_k127_4224558_1 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009245 363.0
TLS3_k127_4224558_10 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000004816 195.0
TLS3_k127_4224558_11 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000003762 181.0
TLS3_k127_4224558_12 4Fe-4S binding domain - - - 0.000000000000000000000000000000187 124.0
TLS3_k127_4224558_13 FR47-like protein - - - 0.00000000000000000000000000000048 134.0
TLS3_k127_4224558_14 Cytidylyltransferase K07141 - 2.7.7.76 0.00000000000000000000000001623 117.0
TLS3_k127_4224558_15 - - - - 0.000000000000000000000001797 113.0
TLS3_k127_4224558_16 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000008124 85.0
TLS3_k127_4224558_17 Redoxin K03564 - 1.11.1.15 0.000000000000001172 87.0
TLS3_k127_4224558_18 DNA-binding transcription factor activity - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000003834 75.0
TLS3_k127_4224558_19 TatD related DNase K03424 - - 0.0000000004254 73.0
TLS3_k127_4224558_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 287.0
TLS3_k127_4224558_20 Methyltransferase domain - - - 0.000003044 58.0
TLS3_k127_4224558_21 HAD-hyrolase-like K01091 - 3.1.3.18 0.0003014 51.0
TLS3_k127_4224558_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001067 266.0
TLS3_k127_4224558_4 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001514 241.0
TLS3_k127_4224558_5 Uncharacterized conserved protein (COG2071) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003736 239.0
TLS3_k127_4224558_6 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001999 231.0
TLS3_k127_4224558_7 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000003204 225.0
TLS3_k127_4224558_8 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000005982 224.0
TLS3_k127_4224558_9 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000002751 197.0
TLS3_k127_4231779_0 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 414.0
TLS3_k127_4231779_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000003096 82.0
TLS3_k127_4231779_2 NUDIX domain - - - 0.0000000000002312 73.0
TLS3_k127_4258996_0 A circularly permuted ATPgrasp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 528.0
TLS3_k127_4258996_1 DNA primase, small subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006838 445.0
TLS3_k127_4258996_10 YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the K09780 - - 0.000000000000000000000000002041 113.0
TLS3_k127_4258996_11 glyoxalase III activity - - - 0.0000000000000000000003591 102.0
TLS3_k127_4258996_12 DinB family - - - 0.000000000000000008282 93.0
TLS3_k127_4258996_13 - - - - 0.000000382 58.0
TLS3_k127_4258996_14 Protein of unknown function (DUF664) - - - 0.000002294 56.0
TLS3_k127_4258996_15 - - - - 0.00002246 53.0
TLS3_k127_4258996_2 ATP dependent DNA ligase C terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 398.0
TLS3_k127_4258996_3 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 364.0
TLS3_k127_4258996_4 Ketopantoate reductase PanE/ApbA C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006103 254.0
TLS3_k127_4258996_5 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000002053 235.0
TLS3_k127_4258996_6 PFAM Anabaena sensory rhodopsin transducer - - - 0.00000000000000000000000000000000000000000000000003956 181.0
TLS3_k127_4258996_7 transglutaminase - - - 0.0000000000000000000000000000000000000000002613 170.0
TLS3_k127_4258996_8 - - - - 0.00000000000000000000000000000000000000006685 160.0
TLS3_k127_4258996_9 PAP2 superfamily - - - 0.0000000000000000000000000000002881 138.0
TLS3_k127_4300369_0 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000005187 121.0
TLS3_k127_4300369_1 Anti-sigma-K factor rskA - - - 0.000000000000443 79.0
TLS3_k127_4323670_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.549e-229 722.0
TLS3_k127_4323670_1 Penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 480.0
TLS3_k127_4323670_10 DNA polymerase III K02341 - 2.7.7.7 0.000000000000000000000000000000006255 141.0
TLS3_k127_4323670_11 competence protein - - - 0.0000000000000000000000000000004075 139.0
TLS3_k127_4323670_12 Bacterial transcriptional activator domain - - - 0.000000000000000000000000002469 120.0
TLS3_k127_4323670_13 HxlR-like helix-turn-helix - - - 0.00000000000000000000000002628 117.0
TLS3_k127_4323670_14 Cytochrome c oxidase K02351,K07245 - - 0.00000000000000000000005835 109.0
TLS3_k127_4323670_15 Glucose sorbosone - - - 0.00000000000000000000149 109.0
TLS3_k127_4323670_16 -acetyltransferase - - - 0.0000000000000000001837 101.0
TLS3_k127_4323670_17 Chorismate mutase type II K04093 - 5.4.99.5 0.000000000000000003003 88.0
TLS3_k127_4323670_18 Iron-binding zinc finger CDGSH type - - - 0.00000000000000000569 85.0
TLS3_k127_4323670_19 Belongs to the HesB IscA family K13628 - - 0.000000004419 62.0
TLS3_k127_4323670_2 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 395.0
TLS3_k127_4323670_20 helix_turn_helix, Lux Regulon - - - 0.00000002469 67.0
TLS3_k127_4323670_21 PFAM von Willebrand factor type A - - - 0.000003691 51.0
TLS3_k127_4323670_22 - - - - 0.000006807 57.0
TLS3_k127_4323670_23 helix_turn_helix ASNC type K03718 - - 0.000009455 53.0
TLS3_k127_4323670_25 Protein of unknown function (DUF1059) - - - 0.0001123 48.0
TLS3_k127_4323670_3 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 306.0
TLS3_k127_4323670_4 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001109 275.0
TLS3_k127_4323670_5 PFAM PSP1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000003416 250.0
TLS3_k127_4323670_6 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000000004517 188.0
TLS3_k127_4323670_7 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000001544 176.0
TLS3_k127_4323670_8 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000004172 168.0
TLS3_k127_4323670_9 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000005797 175.0
TLS3_k127_4342724_0 Acetyl-CoA acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 509.0
TLS3_k127_4342724_1 PFAM ComEC Rec2-related protein K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 349.0
TLS3_k127_4342724_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001553 280.0
TLS3_k127_4342724_3 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001398 261.0
TLS3_k127_4342724_4 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001372 255.0
TLS3_k127_4342724_5 Histidine kinase - - - 0.00000000000000000000000000000000000000001138 164.0
TLS3_k127_4342724_6 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.0000000000000000000000000000813 123.0
TLS3_k127_4342724_7 NYN domain - - - 0.0000000000000000000000000003614 121.0
TLS3_k127_4342724_8 Histidine triad (Hit) protein K02503 - - 0.0000000000002702 82.0
TLS3_k127_4355057_0 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000001586 223.0
TLS3_k127_4355057_1 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000001946 199.0
TLS3_k127_4355057_2 cluster binding protein K18929 - - 0.00000000000000000000000000000000000000000000001392 187.0
TLS3_k127_4355057_3 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000001646 135.0
TLS3_k127_4357545_0 acetyl-coa acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 562.0
TLS3_k127_4357545_1 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000009437 171.0
TLS3_k127_4357545_2 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000002003 152.0
TLS3_k127_4357545_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000001542 141.0
TLS3_k127_4357545_4 Protein of unknown function (DUF455) - - - 0.00000002999 59.0
TLS3_k127_4373710_0 Zinc-binding dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 534.0
TLS3_k127_4373710_1 Enoyl-CoA hydratase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 362.0
TLS3_k127_4373710_10 Formyl transferase - - - 0.0000000000000004594 82.0
TLS3_k127_4373710_11 PFAM blue (type 1) copper domain protein - - - 0.00000000000000993 86.0
TLS3_k127_4373710_2 pterin-4-alpha-carbinolamine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006617 353.0
TLS3_k127_4373710_3 formate dehydrogenase (NAD+) activity K00123,K05299 - 1.17.1.10,1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000008567 239.0
TLS3_k127_4373710_4 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000009548 169.0
TLS3_k127_4373710_5 PFAM Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000114 168.0
TLS3_k127_4373710_6 Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000009872 155.0
TLS3_k127_4373710_7 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000003195 126.0
TLS3_k127_4373710_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000114 112.0
TLS3_k127_4373710_9 Domain of unknown function (DUF4332) - - - 0.000000000000000001072 102.0
TLS3_k127_4407790_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 333.0
TLS3_k127_4407790_1 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004941 271.0
TLS3_k127_4407790_2 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000003884 164.0
TLS3_k127_4407790_3 TIGRFAM PAS domain S-box - - - 0.000000000000000000000000000000000000000002808 160.0
TLS3_k127_4407790_4 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000009485 103.0
TLS3_k127_4407790_5 CopG antitoxin of type II toxin-antitoxin system - - - 0.00000000000002886 77.0
TLS3_k127_4407790_6 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000003464 70.0
TLS3_k127_4432802_0 PFAM Transketolase central region K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 376.0
TLS3_k127_4432802_1 e3 binding domain K00627,K09699 - 2.3.1.12,2.3.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 332.0
TLS3_k127_4432802_2 Dehydrogenase E1 component K00166 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007269 279.0
TLS3_k127_4432802_3 dehydratase - - - 0.0000000000000000001771 101.0
TLS3_k127_4446725_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 418.0
TLS3_k127_4446725_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 379.0
TLS3_k127_4446725_2 CBS domain containing protein K03699 - - 0.000000000000000000000000000000000000000000000000000000000000002967 241.0
TLS3_k127_4473557_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 563.0
TLS3_k127_4473557_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 530.0
TLS3_k127_4473557_10 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K00657 - 2.3.1.57 0.00000000000001717 81.0
TLS3_k127_4473557_11 Methyltransferase domain - - - 0.0000000001028 68.0
TLS3_k127_4473557_13 - - - - 0.000000009923 59.0
TLS3_k127_4473557_14 Tellurite resistance protein TehB - - - 0.00000004144 59.0
TLS3_k127_4473557_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 431.0
TLS3_k127_4473557_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 388.0
TLS3_k127_4473557_4 succinate dehydrogenase K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001062 264.0
TLS3_k127_4473557_5 helix_turn_helix, Lux Regulon K02282 - - 0.0000000000000000000000000000000000000000000000000000001112 203.0
TLS3_k127_4473557_6 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000008802 160.0
TLS3_k127_4473557_7 Maf-like protein K06287 - - 0.000000000000000000000000000000000000003323 160.0
TLS3_k127_4473557_8 Psort location Cytoplasmic, score K01515 - 3.6.1.13 0.00000000000000000000000000000000000002392 154.0
TLS3_k127_4473557_9 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000008741 117.0
TLS3_k127_4474243_0 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 437.0
TLS3_k127_4474243_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 414.0
TLS3_k127_4474243_2 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 396.0
TLS3_k127_4474243_3 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001198 231.0
TLS3_k127_4474243_4 acyl-CoA dehydrogenase K22027 - 1.14.13.235 0.000000000000000000000000000000000000000000000000002268 195.0
TLS3_k127_4474243_5 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000001623 157.0
TLS3_k127_4522697_0 Phosphotriesterase K07048 - - 0.0000000000000000000000000000000000000000000000000007133 194.0
TLS3_k127_4522697_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000003319 179.0
TLS3_k127_4522697_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000001867 115.0
TLS3_k127_4522697_3 O-acyltransferase activity K03818 - - 0.0000355 51.0
TLS3_k127_4527375_0 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 471.0
TLS3_k127_4527375_1 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000003721 207.0
TLS3_k127_4527375_2 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000000002283 128.0
TLS3_k127_4527375_4 DNA-binding transcription factor activity - - - 0.00009202 45.0
TLS3_k127_4527375_5 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0009591 51.0
TLS3_k127_4534507_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 622.0
TLS3_k127_4534507_1 COGs COG2148 Sugar transferase involved in lipopolysaccharide synthesis - - - 0.00000000000000000000003471 103.0
TLS3_k127_4551649_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 626.0
TLS3_k127_4551649_1 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 526.0
TLS3_k127_4551649_10 PAP2 superfamily - - - 0.00000000000000000000000000000000004861 149.0
TLS3_k127_4551649_11 rRNA binding K02956 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000006041 124.0
TLS3_k127_4551649_12 Succinyl-CoA ligase like flavodoxin domain - - - 0.000000000000000000000000839 112.0
TLS3_k127_4551649_13 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000008908 92.0
TLS3_k127_4551649_14 Chromatin associated protein KTI12 - - - 0.00000000000003113 79.0
TLS3_k127_4551649_15 DinB superfamily - - - 0.000005201 55.0
TLS3_k127_4551649_16 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0005037 51.0
TLS3_k127_4551649_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 448.0
TLS3_k127_4551649_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 419.0
TLS3_k127_4551649_4 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 286.0
TLS3_k127_4551649_5 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000001332 262.0
TLS3_k127_4551649_6 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000001619 218.0
TLS3_k127_4551649_7 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000000000000000000000000000005222 216.0
TLS3_k127_4551649_8 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000007942 215.0
TLS3_k127_4551649_9 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000001261 151.0
TLS3_k127_4565103_0 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 456.0
TLS3_k127_4565103_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 404.0
TLS3_k127_4565103_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000002105 260.0
TLS3_k127_4565103_3 cyclic-guanylate-specific phosphodiesterase activity - - - 0.000000000000000000000000000000000000000000000007664 194.0
TLS3_k127_4565103_4 sirohydrochlorin cobaltochelatase activity K03795 - 4.99.1.3 0.000000000000000000000000000000000000000001036 161.0
TLS3_k127_4565103_5 HDOD domain - - - 0.0000000000000000000000000000000000000004653 161.0
TLS3_k127_4565103_6 PFAM cobalamin (vitamin B12) biosynthesis CbiX K03795 - 4.99.1.3 0.00000000000000004963 89.0
TLS3_k127_4565103_8 to Pantoea sp. At-9b, diguanylate cyclase with PAS PAC sensor (NCBI ZP_05729063.1) K21084 - 2.7.7.65 0.000000001013 68.0
TLS3_k127_4597900_0 ABC transporter K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 304.0
TLS3_k127_4597900_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003443 284.0
TLS3_k127_4597900_2 ABC-type Co2 transport system, permease component K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007078 249.0
TLS3_k127_4597900_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000002627 228.0
TLS3_k127_4597900_4 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000000000000000000000000000001168 198.0
TLS3_k127_4597900_5 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000002024 164.0
TLS3_k127_4597900_6 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000001565 158.0
TLS3_k127_4597900_7 PFAM Cyclic nucleotide-binding K10914 - - 0.0000000000000000001549 99.0
TLS3_k127_4597900_8 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000001068 78.0
TLS3_k127_4597900_9 Glycerophosphoryl diester phosphodiesterase family - - - 0.0000003846 60.0
TLS3_k127_4623943_0 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 342.0
TLS3_k127_4623943_1 Nad-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003345 261.0
TLS3_k127_4623943_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000002829 125.0
TLS3_k127_4623943_3 Thioredoxin-like - - - 0.000000000000000000000001372 111.0
TLS3_k127_4623943_4 Hint domain - - - 0.00000000000000000000004119 108.0
TLS3_k127_4653451_0 Cytochrome b subunit of the bc K00412,K02635 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 287.0
TLS3_k127_4653451_1 Cytochrome b(C-terminal)/b6/petD - - - 0.000000000000000000000000000000000000000001364 167.0
TLS3_k127_4653451_2 PFAM Rieske 2Fe-2S domain K02636 - 1.10.9.1 0.00000000000000000000001451 108.0
TLS3_k127_4653451_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000003666 70.0
TLS3_k127_4653451_4 Transglycosylase SLT domain - - - 0.00003489 57.0
TLS3_k127_4680589_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 2.648e-196 621.0
TLS3_k127_4680589_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 379.0
TLS3_k127_4680589_2 PFAM Family of - - - 0.000000000000000000000000000000000000000006012 166.0
TLS3_k127_4680589_3 nitrite transmembrane transporter activity K08177 - - 0.00000000000000000000000000000003914 133.0
TLS3_k127_4680589_4 Domain of unknown function (DUF4157) - - - 0.0000000000000000000000000001737 132.0
TLS3_k127_4710138_0 Protein of unknown function (DUF2961) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 434.0
TLS3_k127_4710138_1 Sulfate transporter K03321 GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 339.0
TLS3_k127_4710138_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005892 284.0
TLS3_k127_4710138_4 GHKL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000006432 260.0
TLS3_k127_4710138_5 Phage capsid family - - - 0.000000000000000000000000000000000000000000000000000001783 196.0
TLS3_k127_4710138_6 Phage capsid family - - - 0.00000000000000000000000000000000000000000000003142 176.0
TLS3_k127_4747093_0 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009489 430.0
TLS3_k127_4747093_1 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 385.0
TLS3_k127_4747093_10 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000001367 121.0
TLS3_k127_4747093_11 Protein of unknown function (DUF433) - - - 0.0000000001388 64.0
TLS3_k127_4747093_12 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.000002591 56.0
TLS3_k127_4747093_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 375.0
TLS3_k127_4747093_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 307.0
TLS3_k127_4747093_4 Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 299.0
TLS3_k127_4747093_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000008368 233.0
TLS3_k127_4747093_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000004927 190.0
TLS3_k127_4747093_7 Thymine DNA K20813 GO:0000122,GO:0000166,GO:0000287,GO:0000700,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003712,GO:0003824,GO:0004844,GO:0005080,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005886,GO:0006139,GO:0006220,GO:0006244,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006298,GO:0006304,GO:0006355,GO:0006357,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008263,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0017076,GO:0018130,GO:0019104,GO:0019219,GO:0019222,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0030554,GO:0030983,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031402,GO:0031404,GO:0031420,GO:0031974,GO:0031981,GO:0032091,GO:0032182,GO:0032183,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035510,GO:0035511,GO:0035561,GO:0035562,GO:0035639,GO:0036094,GO:0040029,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043393,GO:0043412,GO:0043621,GO:0043739,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044728,GO:0045008,GO:0045892,GO:0045934,GO:0045995,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051098,GO:0051100,GO:0051171,GO:0051172,GO:0051239,GO:0051252,GO:0051253,GO:0051336,GO:0051716,GO:0055086,GO:0055114,GO:0060255,GO:0065007,GO:0065009,GO:0070013,GO:0070988,GO:0070989,GO:0071704,GO:0071944,GO:0072527,GO:0072529,GO:0080090,GO:0080111,GO:0090304,GO:0097159,GO:0097367,GO:0097506,GO:0140097,GO:0140110,GO:1901135,GO:1901136,GO:1901265,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1902544,GO:1902679,GO:1903506,GO:1903507,GO:2000026,GO:2000112,GO:2000113,GO:2001141 3.2.2.29 0.00000000000000000000000000000002608 133.0
TLS3_k127_4747093_8 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000002938 133.0
TLS3_k127_4747093_9 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.00000000000000000000000002014 119.0
TLS3_k127_4752708_0 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00003916 57.0
TLS3_k127_4752708_1 - - - - 0.0002242 50.0
TLS3_k127_4783790_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 435.0
TLS3_k127_4783790_1 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001388 282.0
TLS3_k127_4783790_2 decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000002347 248.0
TLS3_k127_4783790_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000002365 192.0
TLS3_k127_4783790_4 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000006068 129.0
TLS3_k127_4783790_5 Metallo-beta-lactamase superfamily - GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0031974,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 - 0.00000000000000000000000000000072 131.0
TLS3_k127_4783790_6 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000001269 83.0
TLS3_k127_4783790_7 Pyridoxamine 5'-phosphate oxidase - - - 0.000001863 58.0
TLS3_k127_4783790_8 Diguanylate cyclase - - - 0.00005068 54.0
TLS3_k127_478450_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 343.0
TLS3_k127_478450_1 Histidine biosynthesis bifunctional protein HisIE K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000002652 132.0
TLS3_k127_478450_2 phosphatase - - - 0.00000000000000000000000000002334 128.0
TLS3_k127_478450_3 Protein of unknown function (DUF2905) - - - 0.00000000000116 76.0
TLS3_k127_48163_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 7.064e-195 627.0
TLS3_k127_48163_1 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004155 259.0
TLS3_k127_48163_10 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000009204 104.0
TLS3_k127_48163_11 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000001838 92.0
TLS3_k127_48163_12 FtsX-like permease family K02004 - - 0.0000003642 61.0
TLS3_k127_48163_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001481 245.0
TLS3_k127_48163_3 Beta-lactamase K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000003146 249.0
TLS3_k127_48163_4 Belongs to the peptidase S41A family K03797 GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000006729 236.0
TLS3_k127_48163_5 Belongs to the FPP GGPP synthase family K13787 GO:0000287,GO:0003674,GO:0003824,GO:0004161,GO:0004659,GO:0005488,GO:0005506,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0030145,GO:0033383,GO:0033384,GO:0033385,GO:0033386,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045337,GO:0045338,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000004729 214.0
TLS3_k127_48163_6 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000006501 193.0
TLS3_k127_48163_7 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000004911 162.0
TLS3_k127_48163_8 Sigma-70 region 3 K02405 - - 0.000000000000000000000000000000000000000001767 166.0
TLS3_k127_48163_9 Aminoglycoside/hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.00000000000000000000008086 109.0
TLS3_k127_4833912_0 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 327.0
TLS3_k127_4833912_1 transport, permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000176 266.0
TLS3_k127_4833912_2 Domain of unknown function (DUF4188) - - - 0.00000000000000000000000000000000000000000000000000000004858 201.0
TLS3_k127_4833912_3 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000001951 143.0
TLS3_k127_4833912_4 helix_turn_helix, mercury resistance - - - 0.000000000000000000000001301 109.0
TLS3_k127_4855971_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 9.695e-223 711.0
TLS3_k127_4855971_1 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.0000000000000000000000000000000000003179 162.0
TLS3_k127_4855971_2 PFAM isocitrate isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000008281 125.0
TLS3_k127_4863992_0 GMC oxidoreductase K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 452.0
TLS3_k127_4863992_1 Acetyl-CoA acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 407.0
TLS3_k127_4863992_10 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000001077 107.0
TLS3_k127_4863992_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004293 291.0
TLS3_k127_4863992_3 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002185 232.0
TLS3_k127_4863992_4 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000003587 233.0
TLS3_k127_4863992_5 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000002659 212.0
TLS3_k127_4863992_6 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000001449 176.0
TLS3_k127_4863992_7 - - - - 0.0000000000000000000000000000000000000000003159 164.0
TLS3_k127_4863992_8 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000004625 156.0
TLS3_k127_4863992_9 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000731 139.0
TLS3_k127_488246_0 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 447.0
TLS3_k127_488246_1 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000005642 219.0
TLS3_k127_488246_2 - - - - 0.0000000000000000000000000000000000000000000000000000005665 199.0
TLS3_k127_488246_3 glycerophosphoryl diester phosphodiesterase - - - 0.000000000000000000000000000000004547 138.0
TLS3_k127_488246_4 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000000000000001101 116.0
TLS3_k127_488246_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000002418 104.0
TLS3_k127_488246_6 HxlR-like helix-turn-helix - - - 0.00000000131 66.0
TLS3_k127_488246_7 Highly conserved protein containing a thioredoxin domain - - - 0.00000000511 68.0
TLS3_k127_488726_0 Penicillin-binding Protein dimerisation domain K03587,K08384 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 366.0
TLS3_k127_488726_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 359.0
TLS3_k127_488726_10 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000001377 213.0
TLS3_k127_488726_11 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000001143 188.0
TLS3_k127_488726_12 Cell division protein FtsQ K03589 - - 0.00000000000000006338 93.0
TLS3_k127_488726_13 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000001136 79.0
TLS3_k127_488726_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 338.0
TLS3_k127_488726_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 336.0
TLS3_k127_488726_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 327.0
TLS3_k127_488726_5 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 311.0
TLS3_k127_488726_6 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 306.0
TLS3_k127_488726_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 298.0
TLS3_k127_488726_8 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000007414 261.0
TLS3_k127_488726_9 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000001852 250.0
TLS3_k127_4902356_0 Carboxylesterase family - - - 0.000000000000000000000000000000000000000000001596 173.0
TLS3_k127_4902356_1 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000000000000000000009465 135.0
TLS3_k127_4902356_2 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000001517 122.0
TLS3_k127_4902356_3 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000001041 95.0
TLS3_k127_4902356_4 Sporulation protein YtfJ - - - 0.00000000000000000578 90.0
TLS3_k127_4930940_0 PGAP1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000005922 216.0
TLS3_k127_4930940_1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.0000000000000000000000000000000000000005858 151.0
TLS3_k127_4930940_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000004004 141.0
TLS3_k127_4930940_3 ECF sigma factor K03088 - - 0.00000000000000000000000792 108.0
TLS3_k127_4930940_4 Transcriptional regulator - - - 0.000000000000000000000008344 106.0
TLS3_k127_4930940_5 polyhydroxyalkanoic acid synthase, PhaR subunit - - - 0.00000000000000002369 87.0
TLS3_k127_4930940_6 Zn peptidase - - - 0.000000003435 69.0
TLS3_k127_497026_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 295.0
TLS3_k127_497026_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000001431 196.0
TLS3_k127_497026_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000003427 171.0
TLS3_k127_5008000_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 9.675e-197 635.0
TLS3_k127_5008000_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 482.0
TLS3_k127_5008000_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 435.0
TLS3_k127_5008000_3 Carbon-nitrogen hydrolase K01501 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 298.0
TLS3_k127_5008000_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000001143 202.0
TLS3_k127_5008000_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000165 102.0
TLS3_k127_5008000_6 SdpI/YhfL protein family - - - 0.0000000002502 65.0
TLS3_k127_5049147_0 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 283.0
TLS3_k127_5049147_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000001179 218.0
TLS3_k127_5049147_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000005002 150.0
TLS3_k127_5049147_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000001299 126.0
TLS3_k127_5096225_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K12952 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 422.0
TLS3_k127_5096225_1 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 329.0
TLS3_k127_5096225_2 alpha, beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003497 252.0
TLS3_k127_5096225_3 Polysaccharide deacetylase K22278 GO:0005575,GO:0016020 3.5.1.104 0.000000000000000000000000000000000000000000001512 175.0
TLS3_k127_5096225_4 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000000000000001827 106.0
TLS3_k127_5096225_5 pyridoxamine 5-phosphate - - - 0.00000000000000032 83.0
TLS3_k127_5096225_6 mRNA binding K07339 - - 0.0000001623 53.0
TLS3_k127_5096225_7 Periplasmic or secreted lipoprotein - - - 0.000001828 51.0
TLS3_k127_5099211_0 Enoyl-CoA hydratase/isomerase K07546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002627 259.0
TLS3_k127_5099211_1 Protein of unknown function (DUF402) - - - 0.00000001255 63.0
TLS3_k127_5099211_2 - - - - 0.0000003527 62.0
TLS3_k127_5100678_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 503.0
TLS3_k127_5100678_1 Alkyl sulfatase and related hydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004797 307.0
TLS3_k127_5100678_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000002844 263.0
TLS3_k127_5100678_3 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000001337 171.0
TLS3_k127_5100678_4 - - - - 0.0000000000000000002228 90.0
TLS3_k127_5100678_5 Protein of unknown function (DUF2283) - - - 0.0000000000000002777 80.0
TLS3_k127_5100678_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester - - - 0.0000000000002485 77.0
TLS3_k127_5117271_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 8.587e-204 647.0
TLS3_k127_5117271_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 591.0
TLS3_k127_5117271_10 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005146 264.0
TLS3_k127_5117271_11 Polyprenyl synthetase K00805,K02523 - 2.5.1.30,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000008327 245.0
TLS3_k127_5117271_12 TIGRFAM hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000186 208.0
TLS3_k127_5117271_13 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000002062 195.0
TLS3_k127_5117271_14 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000008087 188.0
TLS3_k127_5117271_15 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000009332 150.0
TLS3_k127_5117271_16 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.00000000000000000000000001267 115.0
TLS3_k127_5117271_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.00000000000000000000000001611 114.0
TLS3_k127_5117271_18 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000001542 107.0
TLS3_k127_5117271_19 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339,K05578 - 1.6.5.3 0.000000000000000000000003336 108.0
TLS3_k127_5117271_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009923 469.0
TLS3_k127_5117271_20 Haloacid dehalogenase domain protein hydrolase, type 3 - - - 0.000000000000000000000159 109.0
TLS3_k127_5117271_21 regulatory protein, FmdB family - - - 0.000005742 55.0
TLS3_k127_5117271_3 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 466.0
TLS3_k127_5117271_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 411.0
TLS3_k127_5117271_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 397.0
TLS3_k127_5117271_6 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342,K05575 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 397.0
TLS3_k127_5117271_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 389.0
TLS3_k127_5117271_8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 320.0
TLS3_k127_5117271_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001822 282.0
TLS3_k127_5133126_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 319.0
TLS3_k127_5133126_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000004517 231.0
TLS3_k127_5133126_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000002922 196.0
TLS3_k127_5133126_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000009215 189.0
TLS3_k127_5133126_4 Ribosomal protein L13 K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000003643 183.0
TLS3_k127_5133126_5 ribosomal protein l17 K02879 - - 0.00000000000000000000000000000000001519 144.0
TLS3_k127_5133126_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000004236 114.0
TLS3_k127_517589_0 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000001113 166.0
TLS3_k127_517589_1 Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000003116 138.0
TLS3_k127_517589_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000003587 89.0
TLS3_k127_517589_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000001679 68.0
TLS3_k127_5206671_0 Na H antiporter K05565 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008224 600.0
TLS3_k127_5206671_1 Proton-conducting membrane transporter K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 570.0
TLS3_k127_5206671_10 Major Facilitator Superfamily - - - 0.0000000000000003427 91.0
TLS3_k127_5206671_11 Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) K00010 - 1.1.1.18,1.1.1.369 0.000000000000007562 85.0
TLS3_k127_5206671_12 - K07234 - - 0.0000000001598 73.0
TLS3_k127_5206671_13 lactoylglutathione lyase activity - - - 0.0000000199 61.0
TLS3_k127_5206671_14 lactoylglutathione lyase activity - - - 0.00000004711 61.0
TLS3_k127_5206671_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 366.0
TLS3_k127_5206671_3 WYL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009277 267.0
TLS3_k127_5206671_4 Ecdysteroid kinase - - - 0.0000000000000000000000000000000000000000000000000001967 203.0
TLS3_k127_5206671_5 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000005131 152.0
TLS3_k127_5206671_6 Na H antiporter, MnhB K05566 - - 0.000000000000000000000000000000001131 134.0
TLS3_k127_5206671_7 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.000000000000000000000000000002254 124.0
TLS3_k127_5206671_8 Required for disulfide bond formation in some proteins K03611 - - 0.0000000000000000000000000006485 123.0
TLS3_k127_5206671_9 Glycosyltransferase like family 2 - - - 0.0000000000000000008934 97.0
TLS3_k127_5224899_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 389.0
TLS3_k127_5224899_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000002127 257.0
TLS3_k127_5224899_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.00000000000000000000000000001872 123.0
TLS3_k127_5224899_3 PFAM PIN domain - - - 0.000000000000000000000000008027 114.0
TLS3_k127_5224899_4 copG family - - - 0.00000009437 57.0
TLS3_k127_5263285_0 Belongs to the class-I aminoacyl-tRNA synthetase family K15526 - 6.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004626 340.0
TLS3_k127_5263285_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000002246 253.0
TLS3_k127_5263285_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000005797 230.0
TLS3_k127_5263285_3 response - - - 0.00000000000000000000000000000000000000000000000000000000004669 222.0
TLS3_k127_5263285_4 CoA-transferase family III - - - 0.00000000000004632 76.0
TLS3_k127_5263285_5 Bacterial regulatory proteins, tetR family - - - 0.00000004046 63.0
TLS3_k127_5289617_0 MreB/Mbl protein K04043 - - 3.377e-289 899.0
TLS3_k127_5289617_1 TIGRFAM gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.307e-242 760.0
TLS3_k127_5289617_10 Exonuclease K07502 - - 0.000000000000000000000000000000000000000000000634 182.0
TLS3_k127_5289617_11 aminoacyl-tRNA hydrolase activity K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000014 161.0
TLS3_k127_5289617_12 Protein of unknown function (DUF2851) - - - 0.000000000000000000000000000000000007167 151.0
TLS3_k127_5289617_13 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000000000000000000000000000000000009925 150.0
TLS3_k127_5289617_14 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000002082 144.0
TLS3_k127_5289617_15 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000001542 141.0
TLS3_k127_5289617_16 - - - - 0.00000000000000000000000000000006333 134.0
TLS3_k127_5289617_17 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000003389 115.0
TLS3_k127_5289617_18 acetyltransferase K00657 - 2.3.1.57 0.000000000000000000000008235 107.0
TLS3_k127_5289617_19 Anti-sigma-K factor rskA - - - 0.00000000000000000007289 98.0
TLS3_k127_5289617_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 514.0
TLS3_k127_5289617_20 Peptidase family M23 - - - 0.00000000000000000131 97.0
TLS3_k127_5289617_21 dehydratase K18122 - - 0.00000000000000007342 91.0
TLS3_k127_5289617_22 helix-turn-helix domain protein - - - 0.00000000003777 68.0
TLS3_k127_5289617_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 411.0
TLS3_k127_5289617_4 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 381.0
TLS3_k127_5289617_5 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00520 - 1.16.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002109 290.0
TLS3_k127_5289617_6 aldolase K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000001532 237.0
TLS3_k127_5289617_7 Membrane - - - 0.000000000000000000000000000000000000000000000000209 182.0
TLS3_k127_5289617_8 COG0863 DNA modification methylase - - - 0.000000000000000000000000000000000000000000000001399 181.0
TLS3_k127_5289617_9 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000003016 179.0
TLS3_k127_5312509_0 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 628.0
TLS3_k127_5312509_1 elongation factor G K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 580.0
TLS3_k127_5312509_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009367 360.0
TLS3_k127_5312509_3 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000003766 247.0
TLS3_k127_5312509_4 PFAM peptidase - - - 0.0000000000000000000000000000000000000000006518 165.0
TLS3_k127_5312509_5 lytic transglycosylase activity - - - 0.000000000000000000001729 110.0
TLS3_k127_5312509_6 Domain of unknown function (DUF4160) - - - 0.0000000000000000002121 90.0
TLS3_k127_5312509_7 Protein of unknown function (DUF2442) - - - 0.000000004052 59.0
TLS3_k127_532767_0 RmlD substrate binding domain K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000001007 225.0
TLS3_k127_532767_1 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000001554 139.0
TLS3_k127_532767_2 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000006505 131.0
TLS3_k127_532767_4 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.000000000000001142 88.0
TLS3_k127_532767_5 thiamine pyrophosphokinase K00949 - 2.7.6.2 0.000000000000002332 85.0
TLS3_k127_532767_6 - - - - 0.00000000021 72.0
TLS3_k127_532767_7 Part of a membrane complex involved in electron transport K03616 - - 0.00000003955 58.0
TLS3_k127_5328478_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009065 314.0
TLS3_k127_5328478_1 Inositol monophosphatase K01092 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000004582 253.0
TLS3_k127_5328478_2 Enoyl-(Acyl carrier protein) reductase K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000005939 209.0
TLS3_k127_5328478_3 PFAM HhH-GPD superfamily base excision DNA repair protein K01247 - 3.2.2.21 0.000000000165 64.0
TLS3_k127_5341099_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 363.0
TLS3_k127_5341099_1 CHAD domain containing protein - - - 0.000000000000000000000000000000000000002317 155.0
TLS3_k127_5341099_2 Protein of unknown function (DUF433) - - - 0.000000000000001465 78.0
TLS3_k127_5341099_3 - K01822 - 5.3.3.1 0.000000000009475 72.0
TLS3_k127_5350090_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 573.0
TLS3_k127_5350090_1 Cell division protein FtsA K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 427.0
TLS3_k127_5350090_2 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 376.0
TLS3_k127_5350090_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000003578 109.0
TLS3_k127_5350090_4 DNA alkylation repair enzyme - - - 0.0002845 44.0
TLS3_k127_5358207_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 353.0
TLS3_k127_5358207_1 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003307 258.0
TLS3_k127_5358207_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000008428 176.0
TLS3_k127_5358207_3 Alpha/beta hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000003205 181.0
TLS3_k127_5358207_5 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000273 57.0
TLS3_k127_5364531_0 elongation factor G K18220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008705 535.0
TLS3_k127_5364531_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000006355 147.0
TLS3_k127_5364531_2 retrograde transport, endosome to Golgi K07095 - - 0.000000000000000000000000000000002404 136.0
TLS3_k127_5364531_3 Major facilitator superfamily - - - 0.000000000000000000000000001388 127.0
TLS3_k127_5364531_5 Universal stress protein family - - - 0.0000004478 61.0
TLS3_k127_5370362_0 Peptidase family M1 domain K01256 - 3.4.11.2 7.917e-204 663.0
TLS3_k127_5370362_1 dipeptidyl peptidase K01278 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.4.14.5 6.353e-203 653.0
TLS3_k127_5370362_10 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000001024 170.0
TLS3_k127_5370362_11 WYL domain K13572 - - 0.000000000000000000000000000000000000000001588 168.0
TLS3_k127_5370362_12 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000000000000000000000002254 173.0
TLS3_k127_5370362_13 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000004952 144.0
TLS3_k127_5370362_14 Protein of unknown function (DUF3090) - - - 0.00000000000000000000000000005203 122.0
TLS3_k127_5370362_15 SNARE associated Golgi protein - - - 0.00000000000000000001297 102.0
TLS3_k127_5370362_17 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0001198 51.0
TLS3_k127_5370362_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 574.0
TLS3_k127_5370362_3 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 339.0
TLS3_k127_5370362_4 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 297.0
TLS3_k127_5370362_5 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000123 290.0
TLS3_k127_5370362_6 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000007641 248.0
TLS3_k127_5370362_7 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000009992 235.0
TLS3_k127_5370362_8 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000001115 207.0
TLS3_k127_5370362_9 form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.000000000000000000000000000000000000000000000000000000001611 209.0
TLS3_k127_53846_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 353.0
TLS3_k127_53846_1 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 300.0
TLS3_k127_53846_2 ABC-2 family transporter protein K01990,K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008603 266.0
TLS3_k127_53846_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000001597 207.0
TLS3_k127_53846_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000005579 156.0
TLS3_k127_53846_5 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000001943 65.0
TLS3_k127_53846_6 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.000005372 58.0
TLS3_k127_5425027_0 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 317.0
TLS3_k127_5425027_1 carnitine dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 311.0
TLS3_k127_5425027_2 Major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001471 259.0
TLS3_k127_5425027_3 CHAD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005666 251.0
TLS3_k127_5425027_4 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.000000000000000000000000000000000000000000000000000000000000001829 226.0
TLS3_k127_5425027_5 regulation of RNA biosynthetic process - - - 0.000000000000000000000000000000000000000000000000005233 185.0
TLS3_k127_5451177_0 Voltage gated chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 552.0
TLS3_k127_5451177_1 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000134 273.0
TLS3_k127_5451177_10 - - - - 0.0000001476 60.0
TLS3_k127_5451177_11 Sigma-70, region 4 type 2 - - - 0.0007114 47.0
TLS3_k127_5451177_2 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001864 271.0
TLS3_k127_5451177_3 PAC2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000005 232.0
TLS3_k127_5451177_4 ECF transporter, substrate-specific component K16927 - - 0.00000000000000000000000000000000000000000000000000000000000412 218.0
TLS3_k127_5451177_5 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000008001 196.0
TLS3_k127_5451177_6 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.000000000000000000000000000000002854 137.0
TLS3_k127_5451177_7 COG0023 Translation initiation factor 1 (eIF-1 SUI1) and related proteins K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000006366 108.0
TLS3_k127_5451177_8 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000001636 101.0
TLS3_k127_5451177_9 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000000000001962 84.0
TLS3_k127_547038_0 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003651 280.0
TLS3_k127_547038_1 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000002337 221.0
TLS3_k127_547038_2 PFAM regulatory protein, MerR K22491 - - 0.0000000000000000000000000000000000001309 153.0
TLS3_k127_547038_3 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000004202 96.0
TLS3_k127_5474219_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002856 279.0
TLS3_k127_5474219_1 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005543 269.0
TLS3_k127_5474219_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000001346 211.0
TLS3_k127_5474219_3 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000003176 102.0
TLS3_k127_5474219_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000003769 92.0
TLS3_k127_5474219_5 - - - - 0.00000000000008114 81.0
TLS3_k127_5474219_6 Peptidase, M23 family K21471 - - 0.000003708 59.0
TLS3_k127_5474219_7 PFAM RNA polymerase sigma factor 70, region 4 type 2 K03088 - - 0.000004003 56.0
TLS3_k127_5474657_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 548.0
TLS3_k127_5474657_1 Cation transport protein K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 298.0
TLS3_k127_5495738_0 Glutamate synthase central domain K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1296.0
TLS3_k127_5495738_1 COG0493 NADPH-dependent glutamate synthase beta chain and K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 437.0
TLS3_k127_5513401_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 562.0
TLS3_k127_5513401_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008191 511.0
TLS3_k127_5513401_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 404.0
TLS3_k127_5513401_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 379.0
TLS3_k127_5513401_4 Quinolinate phosphoribosyl transferase, N-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000007709 271.0
TLS3_k127_5513401_5 Domain present in PSD-95, Dlg, and ZO-1/2. K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002213 256.0
TLS3_k127_5513401_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000001683 164.0
TLS3_k127_5513401_7 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000009683 147.0
TLS3_k127_5513401_8 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.000000000000000000000001727 111.0
TLS3_k127_5513401_9 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000004488 100.0
TLS3_k127_5526014_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 312.0
TLS3_k127_5526014_1 Formyl transferase - - - 0.000000000000000000000000000000000000000000000002855 182.0
TLS3_k127_5526014_2 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.0003582 51.0
TLS3_k127_55317_0 Cytochrome P450 K05525,K20497 - 1.14.13.151,1.14.15.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 356.0
TLS3_k127_55317_1 Cytochrome P450 K15981 - 1.14.13.141 0.00000000000000000000000000000000000000000000000000004444 199.0
TLS3_k127_55317_2 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000002394 130.0
TLS3_k127_55317_3 Nitroreductase family - - - 0.00000000000000000000000001322 116.0
TLS3_k127_55317_5 Divergent 4Fe-4S mono-cluster K05337 - - 0.000000000004779 71.0
TLS3_k127_5556649_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 297.0
TLS3_k127_5556649_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001347 267.0
TLS3_k127_5556649_2 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000008245 271.0
TLS3_k127_5556649_3 DEAD DEAH box K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000326 246.0
TLS3_k127_5556649_4 Belongs to the FPG family K05522 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000005651 200.0
TLS3_k127_5556649_5 Protein of unknown function (DUF1461) - - - 0.0000000000000000000000003974 116.0
TLS3_k127_5556649_6 Tyrosine phosphatase family K01104 - 3.1.3.48 0.00000000000000000000001456 103.0
TLS3_k127_5556649_7 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 GO:0008150,GO:0040007 1.2.1.70 0.00000000000000004587 93.0
TLS3_k127_5556649_8 - - - - 0.00000000000002652 82.0
TLS3_k127_5556649_9 - - - - 0.0007093 49.0
TLS3_k127_5571652_0 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004042 267.0
TLS3_k127_5571652_1 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000003006 237.0
TLS3_k127_5571652_2 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000001223 177.0
TLS3_k127_5571652_3 guanyl-nucleotide exchange factor activity K05349,K13735,K18491,K20276 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.2.1.21 0.0000000000000000000000000000009969 137.0
TLS3_k127_5571652_4 Redoxin K02199 - - 0.00000000000000000000008732 101.0
TLS3_k127_5575322_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 314.0
TLS3_k127_5575322_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000009032 273.0
TLS3_k127_5575322_2 diguanylate cyclase - - - 0.000000000000000000000000000000588 134.0
TLS3_k127_5575322_3 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000000000000001838 138.0
TLS3_k127_5575322_4 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.000000000000000006289 93.0
TLS3_k127_5575322_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0001912 50.0
TLS3_k127_5587418_0 KR domain K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 344.0
TLS3_k127_5587418_1 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 293.0
TLS3_k127_5587418_2 Pyridoxal-phosphate dependent enzyme K01883,K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47,6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000002759 231.0
TLS3_k127_5587418_3 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000271 121.0
TLS3_k127_558801_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 481.0
TLS3_k127_558801_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 312.0
TLS3_k127_558801_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004904 264.0
TLS3_k127_558801_3 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000002907 228.0
TLS3_k127_558801_4 PFAM extracellular solute-binding protein family 5 K02035 - - 0.00000000000000000000000000000001144 145.0
TLS3_k127_558801_5 Transcriptional regulator - - - 0.00000000000000000000000000000001835 128.0
TLS3_k127_558801_6 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000002287 101.0
TLS3_k127_55899_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 9.649e-223 706.0
TLS3_k127_55899_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 554.0
TLS3_k127_55899_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 462.0
TLS3_k127_55899_3 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 315.0
TLS3_k127_55899_4 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000002086 212.0
TLS3_k127_55899_5 response regulator - - - 0.00000000000000000000000000000000000000000000000000000001168 207.0
TLS3_k127_55899_6 acetolactate synthase K01653,K16785 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000001011 193.0
TLS3_k127_55899_7 Histidine kinase - - - 0.0000000000000000000000005321 119.0
TLS3_k127_55899_8 - - - - 0.0000000000002371 77.0
TLS3_k127_55899_9 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000003251 53.0
TLS3_k127_5591805_0 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 355.0
TLS3_k127_5591805_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 340.0
TLS3_k127_5591805_10 Cell wall-associated hydrolase (invasion-associated protein) - - - 0.0004185 47.0
TLS3_k127_5591805_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 337.0
TLS3_k127_5591805_3 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000204 224.0
TLS3_k127_5591805_4 COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - - - 0.000000000000000000000000000000000000000000000000000000001018 212.0
TLS3_k127_5591805_5 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000001568 209.0
TLS3_k127_5591805_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000003916 168.0
TLS3_k127_5591805_7 translation release factor activity K03265 - - 0.00000000000000000000000102 117.0
TLS3_k127_5591805_8 PAP2 superfamily - - - 0.00000000000000000000001164 112.0
TLS3_k127_5591805_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.0000000000000000000004804 100.0
TLS3_k127_5615537_0 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 295.0
TLS3_k127_5615537_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000001008 160.0
TLS3_k127_5615537_2 Protein of unknown function (DUF402) - - - 0.000000000000000000000000000000000000002187 155.0
TLS3_k127_5657157_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 465.0
TLS3_k127_5657157_1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000001714 246.0
TLS3_k127_5657157_2 DNA packaging - - - 0.000000000000000000000000000000000000000000000000000000000000000008039 243.0
TLS3_k127_5657157_3 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000001275 194.0
TLS3_k127_5657157_4 ABC transporter K01992 - - 0.00000000000000000000000000000000000000000000558 172.0
TLS3_k127_5657157_5 Domain of unknown function (DUF4280) - - - 0.00000000000000000000000000000000000000001983 155.0
TLS3_k127_5657157_6 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00000000000001091 85.0
TLS3_k127_5657157_7 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000002484 85.0
TLS3_k127_5657157_8 - - - - 0.00000000004974 75.0
TLS3_k127_5662258_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 7.662e-297 930.0
TLS3_k127_5662258_1 Heavy metal transport detoxification protein K17686 - 3.6.3.54 1.169e-210 685.0
TLS3_k127_5662258_10 MOSC N-terminal beta barrel domain K07140 - - 0.0000000000000000000000000000000003375 141.0
TLS3_k127_5662258_11 Thioesterase K07107 - - 0.0000000000000000000000000002381 119.0
TLS3_k127_5662258_12 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000959 74.0
TLS3_k127_5662258_13 Heavy metal transport detoxification protein - - - 0.000000000005627 69.0
TLS3_k127_5662258_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.00000000004885 70.0
TLS3_k127_5662258_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 574.0
TLS3_k127_5662258_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 508.0
TLS3_k127_5662258_4 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141 299.0
TLS3_k127_5662258_5 III protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001156 284.0
TLS3_k127_5662258_6 PFAM SMP-30 Gluconolaconase LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000111 257.0
TLS3_k127_5662258_7 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000001785 229.0
TLS3_k127_5662258_8 PFAM Alpha beta hydrolase fold-3 domain protein K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000004208 174.0
TLS3_k127_5662258_9 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000002192 156.0
TLS3_k127_5662996_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 613.0
TLS3_k127_5662996_1 Acetyl-CoA acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 464.0
TLS3_k127_5662996_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 365.0
TLS3_k127_5662996_3 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 308.0
TLS3_k127_5662996_4 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 288.0
TLS3_k127_5662996_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000003291 279.0
TLS3_k127_5662996_6 transcriptional regulator - - - 0.0000000000000000000000000000000000000002675 156.0
TLS3_k127_5662996_7 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000002568 130.0
TLS3_k127_5662996_8 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000004409 130.0
TLS3_k127_5662996_9 lactoylglutathione lyase activity - - - 0.0000000003181 67.0
TLS3_k127_5691491_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1128.0
TLS3_k127_5691491_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 379.0
TLS3_k127_5691491_10 Bacterial transcription activator, effector binding domain K13652 - - 0.00000000000000002782 89.0
TLS3_k127_5691491_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 355.0
TLS3_k127_5691491_3 acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009504 331.0
TLS3_k127_5691491_4 Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK) K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001119 283.0
TLS3_k127_5691491_5 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000194 236.0
TLS3_k127_5691491_6 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000001158 203.0
TLS3_k127_5691491_7 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000005448 198.0
TLS3_k127_5691491_8 Cupin domain - - - 0.00000000000000000000000000000000000000000001461 170.0
TLS3_k127_5691491_9 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000000000000000000000000000000000743 171.0
TLS3_k127_5707830_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 518.0
TLS3_k127_5707830_1 PhoD-like phosphatase K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 411.0
TLS3_k127_5707830_2 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 320.0
TLS3_k127_5707830_4 Phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.0000000000008283 82.0
TLS3_k127_5707830_5 NTF2-like N-terminal transpeptidase domain K05515 - 3.4.16.4 0.000000006364 66.0
TLS3_k127_5708455_0 PFAM Rh family protein ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 423.0
TLS3_k127_5708455_1 Nitrogen regulatory protein P-II - - - 0.0000000000000000000000000000000000000001568 152.0
TLS3_k127_5708455_2 electron transfer flavoprotein K03521 - - 0.00000000000000000001828 94.0
TLS3_k127_5708455_3 response regulator - - - 0.000000005239 68.0
TLS3_k127_5721036_0 DEAD DEAH box K03724 - - 0.0 1288.0
TLS3_k127_5721036_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 329.0
TLS3_k127_5721036_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000003024 184.0
TLS3_k127_5721036_3 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.000000000000000000000000000000000000000000329 169.0
TLS3_k127_5721036_4 COG0563 Adenylate kinase and related - - - 0.0000000000000000000000000000000000000003956 155.0
TLS3_k127_5721036_5 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000001288 134.0
TLS3_k127_5721036_6 Serine aminopeptidase, S33 - - - 0.0000006914 60.0
TLS3_k127_5721036_7 Transglycosylase SLT domain - - - 0.000007246 56.0
TLS3_k127_5721036_8 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0002075 48.0
TLS3_k127_575441_0 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 6.452e-282 883.0
TLS3_k127_575441_1 Predicted methyltransferase regulatory domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000197 279.0
TLS3_k127_575441_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000002276 162.0
TLS3_k127_575441_3 COG3764 Sortase (surface protein transpeptidase) - - - 0.000007489 54.0
TLS3_k127_575441_4 - - - - 0.00004456 48.0
TLS3_k127_5759753_0 Subunit A of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 480.0
TLS3_k127_5759753_1 Proton-conducting membrane transporter K00342,K05575 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 435.0
TLS3_k127_5759753_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 331.0
TLS3_k127_5759753_3 Site-specific DNA-methyltransferase (adenine-specific) K06223 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000002036 233.0
TLS3_k127_5759753_4 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000008106 182.0
TLS3_k127_5759753_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000003103 113.0
TLS3_k127_5759753_6 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000006177 87.0
TLS3_k127_5771166_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 404.0
TLS3_k127_5771166_1 Ribosomal protein S3, C-terminal domain K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003654 282.0
TLS3_k127_5771166_10 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000002601 139.0
TLS3_k127_5771166_11 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000007642 124.0
TLS3_k127_5771166_12 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001972 117.0
TLS3_k127_5771166_13 Ribosomal proteins 50S L24/mitochondrial 39S L24 K02895 - - 0.0000000000000000000000000003881 117.0
TLS3_k127_5771166_14 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000008011 109.0
TLS3_k127_5771166_15 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000803 106.0
TLS3_k127_5771166_16 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000491 104.0
TLS3_k127_5771166_17 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000009727 54.0
TLS3_k127_5771166_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001492 252.0
TLS3_k127_5771166_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001497 247.0
TLS3_k127_5771166_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000002111 212.0
TLS3_k127_5771166_5 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000004274 199.0
TLS3_k127_5771166_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000002528 196.0
TLS3_k127_5771166_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000004363 179.0
TLS3_k127_5771166_8 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000003219 169.0
TLS3_k127_5771166_9 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000009221 162.0
TLS3_k127_5774810_0 transferase activity, transferring glycosyl groups K03271 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008968,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016866,GO:0016868,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 618.0
TLS3_k127_5774810_1 Carbamoyltransferase K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 611.0
TLS3_k127_5774810_10 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 334.0
TLS3_k127_5774810_11 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001123 288.0
TLS3_k127_5774810_12 PFAM glycosyl transferase family 9 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001548 290.0
TLS3_k127_5774810_13 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001829 283.0
TLS3_k127_5774810_14 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000148 267.0
TLS3_k127_5774810_15 HAD-hyrolase-like K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002208 245.0
TLS3_k127_5774810_16 Polynucleotide kinase 3 phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000009221 230.0
TLS3_k127_5774810_17 PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000001669 230.0
TLS3_k127_5774810_18 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000002183 165.0
TLS3_k127_5774810_19 CBS domain - - - 0.0000000000000000000000009535 113.0
TLS3_k127_5774810_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 506.0
TLS3_k127_5774810_3 D-arabinono-1,4-lactone oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 417.0
TLS3_k127_5774810_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 396.0
TLS3_k127_5774810_5 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 385.0
TLS3_k127_5774810_6 COG0405 Gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007552 352.0
TLS3_k127_5774810_7 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 358.0
TLS3_k127_5774810_8 ADP-L-glycero-beta-D-manno-heptose biosynthetic process K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 361.0
TLS3_k127_5774810_9 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 337.0
TLS3_k127_5831771_0 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001823 283.0
TLS3_k127_5831771_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001767 293.0
TLS3_k127_5831771_10 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000002269 63.0
TLS3_k127_5831771_11 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000276 54.0
TLS3_k127_5831771_2 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000003092 215.0
TLS3_k127_5831771_3 60Kd inner membrane protein K03217 - - 0.00000000000000000000000000000000000000000000000000745 192.0
TLS3_k127_5831771_4 Tetratricopeptide repeat K08309 - - 0.00000000000000000000000000000000000000000000009372 192.0
TLS3_k127_5831771_5 Putative single-stranded nucleic acids-binding domain K06346 - - 0.000000000000000000000000001027 126.0
TLS3_k127_5831771_6 PFAM PfkB domain protein - - - 0.00000000000000000000000192 114.0
TLS3_k127_5831771_7 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000005145 100.0
TLS3_k127_5831771_8 serine threonine protein kinase - - - 0.00000000000000003587 94.0
TLS3_k127_5831771_9 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000006779 64.0
TLS3_k127_5863775_0 HI0933-like protein K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 291.0
TLS3_k127_5863775_1 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000005595 206.0
TLS3_k127_5863775_2 diguanylate cyclase K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.000000000000000000000000000003778 132.0
TLS3_k127_5863775_3 Psort location Cytoplasmic, score - - - 0.0000000000000000000000001212 119.0
TLS3_k127_5863775_4 Diguanylate cyclase - - - 0.00000006498 63.0
TLS3_k127_5895569_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 540.0
TLS3_k127_5895569_1 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 422.0
TLS3_k127_5895569_2 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000000000000008879 220.0
TLS3_k127_5895569_3 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III - - - 0.000000000000000002053 93.0
TLS3_k127_5908500_0 PFAM response regulator receiver K07668 - - 0.00000000000000000000000000000000000000000000000000000000000000002248 230.0
TLS3_k127_5908500_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000007014 217.0
TLS3_k127_5908500_2 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000003076 186.0
TLS3_k127_5908500_3 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000008949 61.0
TLS3_k127_5919451_0 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 316.0
TLS3_k127_5919451_1 Belongs to the enoyl-CoA hydratase isomerase family K08299,K16426 GO:0003674,GO:0003824,GO:0004300,GO:0016829,GO:0016835,GO:0016836 4.2.1.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 295.0
TLS3_k127_5919451_2 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000004302 268.0
TLS3_k127_5919451_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000001973 253.0
TLS3_k127_5919451_4 PFAM helix-hairpin-helix motif K03575 - - 0.0000000000000000000000000000000000000000000000000000000000007221 222.0
TLS3_k127_5919451_5 - - - - 0.0000000000000000000000000000000000000000000000000003302 200.0
TLS3_k127_5919451_6 Protein phosphatase 2C K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000003152 143.0
TLS3_k127_5919451_7 RDD family - - - 0.00001877 54.0
TLS3_k127_5921579_0 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008442 412.0
TLS3_k127_5921579_1 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 296.0
TLS3_k127_5921579_2 III protein, CoA-transferase family K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000007582 179.0
TLS3_k127_5921579_3 Secreted and surface protein - - - 0.000000000000000000000000000000000000000004873 173.0
TLS3_k127_5921579_5 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000003558 78.0
TLS3_k127_5921579_6 mRNA binding - - - 0.00000001451 57.0
TLS3_k127_5959893_0 COG1063 Threonine dehydrogenase and related Zn-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 581.0
TLS3_k127_5959893_1 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000002002 117.0
TLS3_k127_5959893_2 COG0857 BioD-like N-terminal domain of phosphotransacetylase K06873 - - 0.0000000000000001493 91.0
TLS3_k127_5960185_0 PFAM NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008923 466.0
TLS3_k127_5960185_1 N,N-dimethylaniline monooxygenase activity K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 437.0
TLS3_k127_5960185_10 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000447 228.0
TLS3_k127_5960185_11 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000006839 197.0
TLS3_k127_5960185_12 Glycosyltransferase like family 2 K07011 - - 0.0000000000000000000000000000000000000000000000005643 186.0
TLS3_k127_5960185_13 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000003164 175.0
TLS3_k127_5960185_14 TIGRFAM molybdenum cofactor synthesis domain - - - 0.00000000000000000000000000000000000000000005498 165.0
TLS3_k127_5960185_15 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000003656 169.0
TLS3_k127_5960185_16 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000002416 158.0
TLS3_k127_5960185_17 PFAM Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000001447 154.0
TLS3_k127_5960185_18 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate - - - 0.000000000000000000000000000443 117.0
TLS3_k127_5960185_19 Putative restriction endonuclease - - - 0.0000000000000000000002162 107.0
TLS3_k127_5960185_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 426.0
TLS3_k127_5960185_20 AsnC family - - - 0.00000000000006336 78.0
TLS3_k127_5960185_21 Dual specificity phosphatase, catalytic domain - - - 0.00001359 54.0
TLS3_k127_5960185_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 372.0
TLS3_k127_5960185_4 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 376.0
TLS3_k127_5960185_5 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 324.0
TLS3_k127_5960185_6 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 320.0
TLS3_k127_5960185_7 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 311.0
TLS3_k127_5960185_8 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000219 262.0
TLS3_k127_5960185_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004061 263.0
TLS3_k127_5980363_0 thiamine transport K02063 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015234,GO:0015238,GO:0015893,GO:0016020,GO:0022857,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0045117,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071934,GO:0071944,GO:0072348,GO:0072531,GO:0090482,GO:1901474,GO:1901682 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008697 483.0
TLS3_k127_5980363_1 Bacterial extracellular solute-binding protein K02064 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 353.0
TLS3_k127_5980363_2 ABC transporter K02010,K02052,K02062 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000001582 233.0
TLS3_k127_5980363_3 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000003777 195.0
TLS3_k127_5980363_4 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000006097 181.0
TLS3_k127_5980363_5 diguanylate cyclase - - - 0.000001176 60.0
TLS3_k127_6022918_0 Biotin carboxylase C-terminal domain - - - 1.788e-211 677.0
TLS3_k127_6022918_1 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000002 200.0
TLS3_k127_6022918_2 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000174 145.0
TLS3_k127_6022918_3 NUDIX domain - - - 0.0000000000000000000000000001623 121.0
TLS3_k127_6022918_4 Alpha beta hydrolase K00433 - 1.11.1.10 0.000000000000000000000000002814 121.0
TLS3_k127_6022918_5 homoserine kinase activity K02204 - 2.7.1.39 0.0000000000000000000001264 111.0
TLS3_k127_6024798_0 Peptidase S15 K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 301.0
TLS3_k127_6024798_1 diguanylate cyclase - - - 0.00000000000000000000000000003261 130.0
TLS3_k127_6024798_2 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000001076 103.0
TLS3_k127_6024798_3 RDD family - - - 0.000007041 56.0
TLS3_k127_6049139_0 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 500.0
TLS3_k127_6049139_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 309.0
TLS3_k127_6049139_2 CoA-transferase family III - - - 0.0000000000000000000000000001726 128.0
TLS3_k127_6049139_3 Bacterial-like globin K06886 - - 0.0000000000000000000000000002194 119.0
TLS3_k127_6049139_4 Putative restriction endonuclease - - - 0.000000000000000000000000000281 121.0
TLS3_k127_6049139_5 methyltransferase - - - 0.000000000000000004971 87.0
TLS3_k127_6050237_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000006784 229.0
TLS3_k127_6050237_1 helix_turn_helix, Lux Regulon - - - 0.00000001873 62.0
TLS3_k127_6058823_0 PFAM ABC transporter related K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 449.0
TLS3_k127_6058823_1 PFAM binding-protein-dependent transport systems inner membrane component K10234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009904 337.0
TLS3_k127_6058823_10 transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000003398 196.0
TLS3_k127_6058823_11 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000419 191.0
TLS3_k127_6058823_12 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000005155 185.0
TLS3_k127_6058823_13 Phosphotransferase enzyme family K18817 - 2.7.1.163 0.000000000000000000000000000000000000000005877 168.0
TLS3_k127_6058823_14 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000002818 151.0
TLS3_k127_6058823_15 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000003504 152.0
TLS3_k127_6058823_16 Succinylglutamate desuccinylase aspartoacylase - - - 0.000000000000000000009915 103.0
TLS3_k127_6058823_17 Putative restriction endonuclease - - - 0.0000000000000000001182 96.0
TLS3_k127_6058823_18 Glutaredoxin-like domain (DUF836) - - - 0.000000000006809 69.0
TLS3_k127_6058823_19 helix_turn_helix, Lux Regulon - - - 0.00000004696 64.0
TLS3_k127_6058823_2 PFAM extracellular solute-binding protein family 1 K10232 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009592 313.0
TLS3_k127_6058823_21 TPR repeat - - - 0.0000007985 54.0
TLS3_k127_6058823_22 protein homooligomerization - - - 0.00001448 56.0
TLS3_k127_6058823_23 - - - - 0.00002949 57.0
TLS3_k127_6058823_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 305.0
TLS3_k127_6058823_4 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002877 287.0
TLS3_k127_6058823_5 Major facilitator Superfamily K08217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001108 287.0
TLS3_k127_6058823_6 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001729 281.0
TLS3_k127_6058823_7 PFAM CobB CobQ domain protein glutamine amidotransferase K07009 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009511 252.0
TLS3_k127_6058823_8 NADPH-dependent FMN reductase K19784 - - 0.00000000000000000000000000000000000000000000000000000000000000000001641 248.0
TLS3_k127_6058823_9 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000006304 208.0
TLS3_k127_6067309_0 Aminotransferase class-V K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 349.0
TLS3_k127_6067309_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 328.0
TLS3_k127_6067309_10 N-terminal half of MaoC dehydratase - - - 0.00007818 50.0
TLS3_k127_6067309_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 310.0
TLS3_k127_6067309_3 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001131 274.0
TLS3_k127_6067309_4 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000001383 239.0
TLS3_k127_6067309_5 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000001034 206.0
TLS3_k127_6067309_6 Na+/Pi-cotransporter - - - 0.0000000000000000000000000000000000000000002669 166.0
TLS3_k127_6067309_7 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000001198 63.0
TLS3_k127_6067309_8 Rieske-like [2Fe-2S] domain - - - 0.00000004686 63.0
TLS3_k127_6067309_9 N-terminal half of MaoC dehydratase - - - 0.00006241 52.0
TLS3_k127_6068554_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 4.754e-204 663.0
TLS3_k127_6068554_1 NADH dehydrogenase K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 479.0
TLS3_k127_6068554_10 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000000007477 199.0
TLS3_k127_6068554_11 - - - - 0.0000000000000000000000000000000000000000002383 167.0
TLS3_k127_6068554_12 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000003667 118.0
TLS3_k127_6068554_13 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000002302 111.0
TLS3_k127_6068554_14 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000001116 103.0
TLS3_k127_6068554_15 - - - - 0.000000003989 67.0
TLS3_k127_6068554_16 - - - - 0.00000001223 65.0
TLS3_k127_6068554_17 response regulator - - - 0.00000182 59.0
TLS3_k127_6068554_18 PFAM GCN5-related N-acetyltransferase - - - 0.00003018 54.0
TLS3_k127_6068554_2 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 466.0
TLS3_k127_6068554_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007664 409.0
TLS3_k127_6068554_4 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 364.0
TLS3_k127_6068554_5 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 379.0
TLS3_k127_6068554_6 Fumarate hydratase (Fumerase) K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 318.0
TLS3_k127_6068554_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006047 271.0
TLS3_k127_6068554_8 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006027 286.0
TLS3_k127_6068554_9 Hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000001026 236.0
TLS3_k127_6102560_0 SMART Glycosyl hydrolase, family 13, subfamily, catalytic domain K05343 - 3.2.1.1,5.4.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 599.0
TLS3_k127_6102560_2 transglycosylase associated protein - - - 0.00000000000000000000000000001001 121.0
TLS3_k127_6102560_3 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000002463 126.0
TLS3_k127_6102560_4 AI-2E family transporter - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000001042 98.0
TLS3_k127_6112102_0 UDP binding domain K02472 - 1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 343.0
TLS3_k127_6112102_1 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001506 292.0
TLS3_k127_6112102_2 Protein of unknown function (DUF559) - - - 0.00000000000000000000001088 104.0
TLS3_k127_6112102_3 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.00000000000000004885 85.0
TLS3_k127_6150276_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 373.0
TLS3_k127_6150276_1 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 301.0
TLS3_k127_6150276_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003315 269.0
TLS3_k127_6150276_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000002208 136.0
TLS3_k127_6150276_4 DegV family - - - 0.00000000001136 76.0
TLS3_k127_6150276_5 Protein of unknown function (DUF1572) - - - 0.0000000007464 67.0
TLS3_k127_6157463_0 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 527.0
TLS3_k127_6157463_1 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000135 280.0
TLS3_k127_6157463_10 NIL - - - 0.00000000000000006197 85.0
TLS3_k127_6157463_11 Putative restriction endonuclease - - - 0.000000000000005452 82.0
TLS3_k127_6157463_12 PFAM Plasmid stabilisation system protein - - - 0.000000000000007306 78.0
TLS3_k127_6157463_13 Biotin-lipoyl like - - - 0.000000000004853 74.0
TLS3_k127_6157463_14 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000002833 71.0
TLS3_k127_6157463_15 - - - - 0.0000000001155 69.0
TLS3_k127_6157463_17 - - - - 0.0000186 52.0
TLS3_k127_6157463_2 Family of unknown function (DUF5305) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003056 279.0
TLS3_k127_6157463_3 TrkA-C domain K03499 - - 0.000000000000000000000000000000000000000000000000003217 195.0
TLS3_k127_6157463_4 PFAM TrkA-N domain protein K03499 - - 0.000000000000000000000000000000000000000006778 162.0
TLS3_k127_6157463_5 Molybdopterin converting factor, small subunit K03636 - - 0.000000000000000000000000000001449 125.0
TLS3_k127_6157463_6 Addiction module toxin, RelE StbE family - - - 0.00000000000000000000000000007991 118.0
TLS3_k127_6157463_7 XdhC and CoxI family - - - 0.0000000000000000000000004469 108.0
TLS3_k127_6157463_8 - - - - 0.000000000000000000007593 96.0
TLS3_k127_6157463_9 Universal stress protein family - - - 0.0000000000000000007235 93.0
TLS3_k127_6171355_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 5.558e-236 754.0
TLS3_k127_6171355_1 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000005796 190.0
TLS3_k127_6171355_2 PFAM Peptidase family M23 - - - 0.000000000000000000000000976 116.0
TLS3_k127_6171355_3 Major Facilitator Superfamily - - - 0.0000000000000000000005221 102.0
TLS3_k127_6171355_5 Cytochrome oxidase assembly protein K02259 - - 0.000000000000002226 80.0
TLS3_k127_6186426_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000003506 177.0
TLS3_k127_6186426_1 competence protein COMEC - - - 0.0000000000000000000000000000001057 137.0
TLS3_k127_6186426_2 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.0000000000000000000000000000001645 138.0
TLS3_k127_6205472_0 ACT domain K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 481.0
TLS3_k127_6205472_1 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 441.0
TLS3_k127_6205472_10 Belongs to the Dps family K04047 - - 0.00000000000000000000000000005536 123.0
TLS3_k127_6205472_2 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002398 270.0
TLS3_k127_6205472_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005797 246.0
TLS3_k127_6205472_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000006389 226.0
TLS3_k127_6205472_5 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000001288 232.0
TLS3_k127_6205472_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000002194 233.0
TLS3_k127_6205472_7 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000002342 213.0
TLS3_k127_6205472_8 Transposase - - - 0.000000000000000000000000000001065 127.0
TLS3_k127_6212002_0 Acyl-CoA dehydrogenase type 2 domain K00249 - 1.3.8.7 9.05e-199 625.0
TLS3_k127_6212002_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 387.0
TLS3_k127_6212002_10 Flavin reductase like domain - - - 0.0000000000000000000000000006175 123.0
TLS3_k127_6212002_11 Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate K01647 - 2.3.3.1 0.0000000000000000000000001265 106.0
TLS3_k127_6212002_12 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000117 109.0
TLS3_k127_6212002_13 PFAM Peptidase M22, glycoprotease K14742 GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.0000000000000378 81.0
TLS3_k127_6212002_14 Helix-turn-helix XRE-family like proteins - - - 0.000002563 57.0
TLS3_k127_6212002_15 helix_turn_helix, Lux Regulon K07685 - - 0.000002738 58.0
TLS3_k127_6212002_16 Putative zinc- or iron-chelating domain K06940 - - 0.000452 51.0
TLS3_k127_6212002_2 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 341.0
TLS3_k127_6212002_3 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000706 235.0
TLS3_k127_6212002_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000001564 202.0
TLS3_k127_6212002_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000001266 186.0
TLS3_k127_6212002_6 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000003792 179.0
TLS3_k127_6212002_7 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000008247 148.0
TLS3_k127_6212002_8 PFAM Uncharacterised protein family UPF0079, ATPase K06925 - - 0.00000000000000000000000000000000272 135.0
TLS3_k127_6212002_9 regulatory protein TetR - - - 0.00000000000000000000000000000002565 133.0
TLS3_k127_6215046_0 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 294.0
TLS3_k127_6215046_1 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000042 282.0
TLS3_k127_6215046_2 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000117 273.0
TLS3_k127_6215046_3 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000001141 184.0
TLS3_k127_6215046_4 Methyltransferase domain K07003 - - 0.00000000000000000000000008261 119.0
TLS3_k127_6215046_5 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000003622 109.0
TLS3_k127_6215046_6 Rhodanese Homology Domain - - - 0.00000000000001721 80.0
TLS3_k127_6239263_0 PFAM DNA RNA tunnel of bacterial DNA dependent RNA polymerase - - - 0.0000000000000000000000000000000000000000000000000000000001874 214.0
TLS3_k127_6239263_1 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000199 126.0
TLS3_k127_6239263_2 Psort location Cytoplasmic, score 8.87 - - - 0.000007813 55.0
TLS3_k127_6247492_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 293.0
TLS3_k127_6247492_1 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 294.0
TLS3_k127_6247492_2 metal-dependent phosphohydrolase, HD sub domain K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001889 295.0
TLS3_k127_6247492_3 Domain of unknown function (DUF4389) - - - 0.000000000000000000000000000000009603 136.0
TLS3_k127_6247492_4 Yqey-like protein K09117 - - 0.0000000000000000000000000000001503 131.0
TLS3_k127_6247492_5 Domain of unknown function (DUF4389) - - - 0.00000000000000000000002054 115.0
TLS3_k127_6247492_6 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.0000000000000000004308 96.0
TLS3_k127_6247492_7 Protein of unknown function (DUF805) - - - 0.00000000000002643 80.0
TLS3_k127_6247492_8 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000002781 64.0
TLS3_k127_6247492_9 RDD family - - - 0.0001325 51.0
TLS3_k127_6258327_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 621.0
TLS3_k127_6261245_0 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 299.0
TLS3_k127_6261245_1 Protein of unknown function (DUF2889) K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000009919 170.0
TLS3_k127_6261245_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000001506 135.0
TLS3_k127_6261245_3 4Fe-4S binding domain - - - 0.00000000000000000000000000004244 119.0
TLS3_k127_6285743_0 aminoglycoside hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 288.0
TLS3_k127_6285743_1 exodeoxyribonuclease I activity - - - 0.00000000000000000000000000000199 129.0
TLS3_k127_6285743_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000005101 132.0
TLS3_k127_6285743_3 Carboxypeptidase K21464 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.4.1.129,3.4.16.4 0.0000000000004154 83.0
TLS3_k127_6316345_0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 301.0
TLS3_k127_6316345_1 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 295.0
TLS3_k127_6316345_10 Flagellar basal body rod protein K02392 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.000000000000000000000002762 108.0
TLS3_k127_6316345_12 peptidase C60 sortase A and B K07284 - 3.4.22.70 0.0000000000000001864 89.0
TLS3_k127_6316345_13 flagellar protein fliS K02422 GO:0001539,GO:0003674,GO:0005198,GO:0006928,GO:0008150,GO:0009987,GO:0040011,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - 0.0000000000005358 75.0
TLS3_k127_6316345_14 Anti-sigma-28 factor, FlgM K02398 - - 0.0004414 48.0
TLS3_k127_6316345_15 factor, FlgM K02398 - - 0.0006682 47.0
TLS3_k127_6316345_2 TIGRFAM Flagellar hook-associated protein, FlgK K02396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009178 278.0
TLS3_k127_6316345_3 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.000000000000000000000000000000000000000000000000000000000000000000002078 256.0
TLS3_k127_6316345_4 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.000000000000000000000000000000000000000000000000000000000000000000002096 263.0
TLS3_k127_6316345_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000000006098 230.0
TLS3_k127_6316345_6 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000003554 202.0
TLS3_k127_6316345_7 Belongs to the bacterial flagellin family K02397 - - 0.000000000000000000000000000000000000000007377 171.0
TLS3_k127_6316345_8 flagellar basal-body rod protein FlgG K02392 - - 0.0000000000000000000000000000000000000008972 157.0
TLS3_k127_6316345_9 Carboxylesterase family - - - 0.00000000000000000000000002215 117.0
TLS3_k127_6334668_0 protein refolding K04077 GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 - 7.737e-203 645.0
TLS3_k127_6334668_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001004 271.0
TLS3_k127_6334668_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000002364 158.0
TLS3_k127_6334668_4 Pfam:DUF385 - - - 0.00000000000000000000000000002806 121.0
TLS3_k127_6334668_5 Winged helix-turn-helix DNA-binding - - - 0.0000000000000000000000002278 108.0
TLS3_k127_6334668_6 nuclease activity K06218 - - 0.000000002439 61.0
TLS3_k127_6334668_7 helix_turn_helix, Lux Regulon - - - 0.000001406 61.0
TLS3_k127_6334668_8 - - - - 0.0000276 54.0
TLS3_k127_6403456_0 acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 340.0
TLS3_k127_6403456_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 337.0
TLS3_k127_6403456_10 dehydratase - - - 0.000000009902 64.0
TLS3_k127_6403456_11 Yip1 domain - - - 0.000000392 59.0
TLS3_k127_6403456_2 acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 322.0
TLS3_k127_6403456_3 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 301.0
TLS3_k127_6403456_4 COG0657 Esterase lipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002775 250.0
TLS3_k127_6403456_5 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000002673 131.0
TLS3_k127_6403456_6 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000002171 126.0
TLS3_k127_6403456_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000009352 127.0
TLS3_k127_6403456_8 Major Facilitator Superfamily - - - 0.0000000000000000000000000468 122.0
TLS3_k127_6403456_9 Phosphotransferase enzyme family - - - 0.00000000000003027 83.0
TLS3_k127_6418865_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000002739 132.0
TLS3_k127_6418865_1 - - - - 0.0007009 52.0
TLS3_k127_6481701_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 398.0
TLS3_k127_6481701_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 328.0
TLS3_k127_6481701_10 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000001923 76.0
TLS3_k127_6481701_2 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000174 277.0
TLS3_k127_6481701_3 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000001265 212.0
TLS3_k127_6481701_4 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000001153 131.0
TLS3_k127_6481701_5 MFS_1 like family - - - 0.00000000000000000000000000000003347 139.0
TLS3_k127_6481701_6 Shikimate kinase - - - 0.00000000000000000000000000000003914 133.0
TLS3_k127_6481701_7 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 0.0000000000000000000000000000001527 132.0
TLS3_k127_6481701_8 PFAM DSBA oxidoreductase - - - 0.00000000000000000000000002205 121.0
TLS3_k127_6481701_9 Membrane - - - 0.000000000000000005648 94.0
TLS3_k127_6485962_0 MBOAT, membrane-bound O-acyltransferase family K03739,K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 443.0
TLS3_k127_6485962_1 diaminopimelate decarboxylase activity K01586,K12526 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4,4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 428.0
TLS3_k127_6485962_10 Protein of unknown function (DUF459) K09795 - - 0.0000000000000000000002897 108.0
TLS3_k127_6485962_11 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.0000007263 62.0
TLS3_k127_6485962_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 347.0
TLS3_k127_6485962_3 COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000000006109 228.0
TLS3_k127_6485962_4 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000004531 214.0
TLS3_k127_6485962_5 Serine aminopeptidase, S33 K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000003691 212.0
TLS3_k127_6485962_6 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000004333 203.0
TLS3_k127_6485962_7 Benzoate membrane transport protein K05782 - - 0.000000000000000000000000000000000000000001253 173.0
TLS3_k127_6485962_8 Protein of unknown function (DUF459) K09795 - - 0.000000000000000000000000000000000000000002402 169.0
TLS3_k127_6485962_9 Belongs to the ClpS family K06891 - - 0.0000000000000000000000000001935 118.0
TLS3_k127_6516851_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000005346 152.0
TLS3_k127_6516851_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000001362 88.0
TLS3_k127_6516851_2 Helix-turn-helix domain - - - 0.000000000000000389 89.0
TLS3_k127_6516851_3 Putative regulatory protein - - - 0.000003599 53.0
TLS3_k127_6521731_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 561.0
TLS3_k127_6521731_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 386.0
TLS3_k127_6521731_10 Guanylate cyclase - GO:0000287,GO:0003674,GO:0003824,GO:0004016,GO:0004383,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006182,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0007186,GO:0007187,GO:0007188,GO:0007189,GO:0008074,GO:0008150,GO:0008152,GO:0008179,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0010033,GO:0014070,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019899,GO:0019932,GO:0019933,GO:0019935,GO:0023052,GO:0030145,GO:0030425,GO:0031224,GO:0031226,GO:0031683,GO:0032991,GO:0033993,GO:0034641,GO:0034654,GO:0035556,GO:0035690,GO:0036477,GO:0042221,GO:0042493,GO:0042995,GO:0043005,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044444,GO:0044445,GO:0044459,GO:0044463,GO:0044464,GO:0044877,GO:0045121,GO:0046058,GO:0046068,GO:0046390,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0046982,GO:0046983,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052652,GO:0055086,GO:0061478,GO:0065007,GO:0070887,GO:0071236,GO:0071310,GO:0071396,GO:0071407,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097305,GO:0097306,GO:0097447,GO:0097458,GO:0098589,GO:0098805,GO:0098857,GO:0120025,GO:0120038,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901654,GO:1901655,GO:1901700,GO:1901701,GO:1904321,GO:1904322 - 0.0000002202 65.0
TLS3_k127_6521731_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 365.0
TLS3_k127_6521731_3 Binding-protein-dependent transport system inner membrane component K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 314.0
TLS3_k127_6521731_4 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 300.0
TLS3_k127_6521731_5 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 302.0
TLS3_k127_6521731_6 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006894 291.0
TLS3_k127_6521731_7 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004506 276.0
TLS3_k127_6521731_8 Peptidoglycan-binding domain 1 protein K17733 - - 0.00000000000000000000000000000000000000000000000000000000000004487 241.0
TLS3_k127_6521731_9 response regulator - - - 0.00000000000000000000000009353 111.0
TLS3_k127_6533098_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 539.0
TLS3_k127_6533098_1 Belongs to the ABC transporter superfamily K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 483.0
TLS3_k127_6533098_10 Belongs to the UPF0235 family K09131 - - 0.000000000000005922 77.0
TLS3_k127_6533098_11 (FHA) domain - - - 0.0000000000003911 80.0
TLS3_k127_6533098_12 PFAM Forkhead-associated protein - - - 0.000000000002908 73.0
TLS3_k127_6533098_13 glycerophosphoryl diester phosphodiesterase - - - 0.0003469 52.0
TLS3_k127_6533098_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 458.0
TLS3_k127_6533098_3 Belongs to the ABC transporter superfamily K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 455.0
TLS3_k127_6533098_4 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 321.0
TLS3_k127_6533098_5 PFAM penicillin-binding protein transpeptidase K05364 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004748 293.0
TLS3_k127_6533098_6 Belongs to the SEDS family K03588 GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 0.000000000000000000000000000000000000000000000000000000000000000000301 247.0
TLS3_k127_6533098_7 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000006853 220.0
TLS3_k127_6533098_8 Modulates RecA activity K03565 - - 0.000000000000000000009182 101.0
TLS3_k127_6533098_9 ATP-dependent transcriptional regulator K03556 - - 0.0000000000000008151 86.0
TLS3_k127_6542016_0 SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008547 287.0
TLS3_k127_6542016_1 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000002514 219.0
TLS3_k127_6542016_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000002933 82.0
TLS3_k127_6580198_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1177.0
TLS3_k127_6580198_1 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 301.0
TLS3_k127_6580198_2 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000535 256.0
TLS3_k127_6580198_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000001016 243.0
TLS3_k127_6580198_4 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000002611 140.0
TLS3_k127_6580806_0 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000004164 178.0
TLS3_k127_6580806_1 CGNR zinc finger - - - 0.0000000000000000000008665 100.0
TLS3_k127_6580806_2 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000001403 96.0
TLS3_k127_6580806_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000003726 80.0
TLS3_k127_6580806_4 Acetyltransferase (GNAT) domain - - - 0.00000001375 63.0
TLS3_k127_6683338_0 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 445.0
TLS3_k127_6683338_1 cellular response to dsDNA K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000002128 193.0
TLS3_k127_6698380_0 flavoprotein involved in K transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 617.0
TLS3_k127_6698380_1 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 308.0
TLS3_k127_6698380_10 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000002037 138.0
TLS3_k127_6698380_11 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000002128 134.0
TLS3_k127_6698380_12 PFAM PIN domain - - - 0.00000000000000000000000000000001117 133.0
TLS3_k127_6698380_13 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.0000000000000000000000000000001239 128.0
TLS3_k127_6698380_14 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000001774 124.0
TLS3_k127_6698380_15 cell envelope-related transcriptional attenuator - - - 0.000000000000000000000000008865 125.0
TLS3_k127_6698380_16 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.00000000000000000000001905 105.0
TLS3_k127_6698380_17 Metal dependent phosphohydrolases with conserved 'HD' motif. K00969 - 2.7.7.18 0.00000000000000000001623 99.0
TLS3_k127_6698380_18 SpoVT / AbrB like domain - - - 0.0000000000008078 72.0
TLS3_k127_6698380_19 PFAM Flavin - - - 0.0000001117 63.0
TLS3_k127_6698380_2 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 303.0
TLS3_k127_6698380_20 Rhodanese Homology Domain - - - 0.00001248 47.0
TLS3_k127_6698380_21 Psort location CytoplasmicMembrane, score - - - 0.0009201 45.0
TLS3_k127_6698380_3 beta-N-acetylhexosaminidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001453 292.0
TLS3_k127_6698380_4 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001241 278.0
TLS3_k127_6698380_5 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000001074 236.0
TLS3_k127_6698380_6 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000006766 231.0
TLS3_k127_6698380_7 N-terminal half of MaoC dehydratase K17865 - 4.2.1.55 0.0000000000000000000000000000000000000000000000009579 179.0
TLS3_k127_6698380_8 TIGRFAM deazaflavin-dependent nitroreductase family protein - - - 0.000000000000000000000000000000000000000000000001021 178.0
TLS3_k127_6698380_9 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000007721 143.0
TLS3_k127_6701817_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.708e-242 769.0
TLS3_k127_6701817_1 COG4263 Nitrous oxide reductase K00376 - 1.7.2.4 8.704e-201 645.0
TLS3_k127_6701817_10 Cupredoxin-like domain - - - 0.000359 49.0
TLS3_k127_6701817_2 type II secretion system protein E K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 481.0
TLS3_k127_6701817_3 Transcriptional regulator, Crp Fnr family K10914,K21563 - - 0.0000000000000000000000000000000000004447 149.0
TLS3_k127_6701817_4 Type II secretion system (T2SS), protein F K12510 - - 0.0000000000000000000000000000000000859 153.0
TLS3_k127_6701817_5 PFAM type II secretion system K12511 - - 0.000000000000000000000000000000002161 140.0
TLS3_k127_6701817_6 Belongs to the heme-copper respiratory oxidase family - - - 0.00000000000000000000000000008212 131.0
TLS3_k127_6701817_7 Type II secretion system (T2SS), protein F K12511 - - 0.00000000000000000002271 107.0
TLS3_k127_6701817_8 Pfam:DUF59 - - - 0.0000000000006647 81.0
TLS3_k127_6701817_9 peptidase K02654 - 3.4.23.43 0.000007703 57.0
TLS3_k127_6710941_0 PFAM peptidase S49 K04773,K04774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005558 265.0
TLS3_k127_6710941_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000002716 247.0
TLS3_k127_6710941_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000002696 135.0
TLS3_k127_6710941_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K00640,K07062 - 2.3.1.30 0.000000000000000000000000000006443 123.0
TLS3_k127_6710941_4 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000002137 118.0
TLS3_k127_6710941_5 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000002655 59.0
TLS3_k127_6710941_6 homoserine kinase activity - - - 0.0001451 54.0
TLS3_k127_6710941_7 toxin-antitoxin pair type II binding - - - 0.0001549 52.0
TLS3_k127_6710941_8 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0002229 48.0
TLS3_k127_6710941_9 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0006758 48.0
TLS3_k127_6714471_0 unusual protein kinase - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009803 378.0
TLS3_k127_6714471_1 TrkA-C domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 381.0
TLS3_k127_6714471_2 Methyltransferase small domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 332.0
TLS3_k127_6714471_3 L-lysine catabolic process to acetate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 299.0
TLS3_k127_6714471_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000253 148.0
TLS3_k127_6714471_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.00000000000000000000001069 104.0
TLS3_k127_6714471_6 Serine aminopeptidase, S33 - - - 0.0000000007394 63.0
TLS3_k127_6720775_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.855e-231 726.0
TLS3_k127_6720775_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 307.0
TLS3_k127_6720775_10 PFAM YeeE YedE family (DUF395) K07112 - - 0.000000000000000000000000000002925 128.0
TLS3_k127_6720775_11 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K02282 - - 0.000000000000000000000000000004305 133.0
TLS3_k127_6720775_12 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000002061 115.0
TLS3_k127_6720775_13 transmembrane transporter activity K02445 - - 0.000000000000000000000001418 117.0
TLS3_k127_6720775_14 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000001529 115.0
TLS3_k127_6720775_15 transporter K07112 - - 0.0000000000000000000002609 108.0
TLS3_k127_6720775_16 Psort location Cytoplasmic, score - - - 0.00000000006132 72.0
TLS3_k127_6720775_17 Belongs to the ParA family K03609 - - 0.00002835 50.0
TLS3_k127_6720775_18 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0001428 50.0
TLS3_k127_6720775_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001218 284.0
TLS3_k127_6720775_3 - - - - 0.000000000000000000000000000000000000000000000000000000000006927 216.0
TLS3_k127_6720775_4 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000012 184.0
TLS3_k127_6720775_5 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000000000005441 167.0
TLS3_k127_6720775_6 Protein of unknown function (DUF402) K09145 - - 0.00000000000000000000000000000000000006013 149.0
TLS3_k127_6720775_7 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000001789 156.0
TLS3_k127_6720775_8 LuxR family transcriptional regulator - - - 0.00000000000000000000000000000001987 139.0
TLS3_k127_6720775_9 Transcriptional regulator - - - 0.00000000000000000000000000000102 134.0
TLS3_k127_6748739_0 Thiolase, C-terminal domain K00626,K02615 - 2.3.1.174,2.3.1.223,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 303.0
TLS3_k127_6748739_1 YceI-like domain - - - 0.00000000000000000000001595 109.0
TLS3_k127_6748739_2 DJ-1/PfpI family - - - 0.00000000006874 63.0
TLS3_k127_6748739_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000151 62.0
TLS3_k127_6783968_0 Glycolate oxidase subunit GlcD K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 483.0
TLS3_k127_6783968_1 Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 331.0
TLS3_k127_6783968_2 PFAM FAD linked oxidase domain protein K00104,K11472 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000001003 233.0
TLS3_k127_6783968_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000001883 195.0
TLS3_k127_6783968_4 SUF system FeS assembly protein K04488 - - 0.00000000000000000000000000000000000000001049 159.0
TLS3_k127_6783968_5 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000000001811 143.0
TLS3_k127_6783968_6 metal-sulfur cluster biosynthetic enzyme K02612 - - 0.0000000000000000000000000006551 117.0
TLS3_k127_6806844_0 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 403.0
TLS3_k127_6806844_1 PFAM Translin K07477 - - 0.000000000000000000000000000000000000000000000000000000007215 204.0
TLS3_k127_6806844_2 Dehydrogenase K00030,K00052 - 1.1.1.41,1.1.1.85 0.0000000000000000000000000000000000001805 144.0
TLS3_k127_6806844_3 - - - - 0.00000000000000000000000000000001463 132.0
TLS3_k127_6806844_4 Electron transfer DM13 - - - 0.0000000000000001116 87.0
TLS3_k127_6806844_5 Putative regulatory protein - - - 0.0000000000005343 73.0
TLS3_k127_6810992_0 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 411.0
TLS3_k127_6810992_1 Tryptophan synthase alpha chain K01694,K10882 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000005023 256.0
TLS3_k127_6810992_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000524 168.0
TLS3_k127_6810992_3 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000009911 163.0
TLS3_k127_6810992_4 chorismate mutase K06208 - 5.4.99.5 0.0000000000000000000000000000000000000009576 153.0
TLS3_k127_6810992_5 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944 - 0.000000000000001143 81.0
TLS3_k127_6810992_6 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000004535 75.0
TLS3_k127_6810992_7 CAAX protease self-immunity K07052 - - 0.0000000004681 68.0
TLS3_k127_681787_0 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000004569 206.0
TLS3_k127_681787_1 beta-lactamase - - - 0.000000000000000000000000003452 119.0
TLS3_k127_685816_0 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009204 454.0
TLS3_k127_685816_1 Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 323.0
TLS3_k127_685816_2 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000008559 74.0
TLS3_k127_685816_3 Secreted repeat of unknown function - - - 0.0000000306 66.0
TLS3_k127_6866486_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001,K14446 - 1.1.1.1,1.3.1.85 2.652e-195 617.0
TLS3_k127_6866486_1 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 582.0
TLS3_k127_6866486_2 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 431.0
TLS3_k127_6866486_3 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000001183 218.0
TLS3_k127_6866486_4 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000001976 209.0
TLS3_k127_6866486_5 exodeoxyribonuclease I activity - - - 0.00000000000000000000000000000000000001708 149.0
TLS3_k127_6866486_6 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.000000000000000000000000002763 125.0
TLS3_k127_6866486_7 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.0000000000000000000000000247 117.0
TLS3_k127_6866486_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000001541 108.0
TLS3_k127_6866486_9 peroxisomal hydratase-dehydrogenase-epimerase K14729 - - 0.0000001381 63.0
TLS3_k127_6880912_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 604.0
TLS3_k127_6880912_1 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000008855 231.0
TLS3_k127_6880912_10 Plasmid stability protein K21495 - - 0.00000000304 61.0
TLS3_k127_6880912_2 Lysophospholipase L1 and related esterases - - - 0.00000000000000000000000000026 115.0
TLS3_k127_6880912_3 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000151 119.0
TLS3_k127_6880912_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000002857 106.0
TLS3_k127_6880912_6 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000004878 79.0
TLS3_k127_6880912_7 DinB family - - - 0.00000000000002711 78.0
TLS3_k127_6880912_8 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000001226 74.0
TLS3_k127_6880912_9 SPTR D1C1B9 DinB family protein - - - 0.0000000000003004 76.0
TLS3_k127_6883920_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 536.0
TLS3_k127_6883920_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 353.0
TLS3_k127_6883920_10 - - - - 0.000000000000000002941 90.0
TLS3_k127_6883920_11 May be involved in recombinational repair of damaged DNA K03631 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000001753 64.0
TLS3_k127_6883920_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 299.0
TLS3_k127_6883920_3 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000001409 229.0
TLS3_k127_6883920_4 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000001322 214.0
TLS3_k127_6883920_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000005984 208.0
TLS3_k127_6883920_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000005131 206.0
TLS3_k127_6883920_7 PFAM UbiA prenyltransferase - - - 0.000000000000000000000000000000000000000000000000000002154 204.0
TLS3_k127_6883920_8 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000002078 137.0
TLS3_k127_6883920_9 Protein of unknown function (DUF433) - - - 0.0000000000000000004907 90.0
TLS3_k127_6904823_0 Copper amine oxidase, enzyme domain K00276 - 1.4.3.21 1.085e-244 771.0
TLS3_k127_6904823_1 Luciferase-like monooxygenase - - - 6.548e-204 644.0
TLS3_k127_6904823_10 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000004846 59.0
TLS3_k127_6904823_2 Belongs to the TPP enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009663 552.0
TLS3_k127_6904823_3 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 374.0
TLS3_k127_6904823_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 364.0
TLS3_k127_6904823_5 PFAM type II secretion system K12511 - - 0.00000000000000000000000000000000000000000000000001808 190.0
TLS3_k127_6904823_6 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000018 129.0
TLS3_k127_6904823_7 Acetyltransferase - - - 0.000000000000000000000284 100.0
TLS3_k127_6904823_8 SnoaL-like domain K06893 - - 0.0000000000000000000004308 104.0
TLS3_k127_6904823_9 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000005572 66.0
TLS3_k127_6907405_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 347.0
TLS3_k127_6907405_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 323.0
TLS3_k127_6907405_10 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000007204 111.0
TLS3_k127_6907405_11 Dehydrogenase - - - 0.000003172 49.0
TLS3_k127_6907405_2 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 306.0
TLS3_k127_6907405_3 PFAM EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003253 298.0
TLS3_k127_6907405_4 polyphosphate glucokinase K00845,K00886 - 2.7.1.2,2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000006404 242.0
TLS3_k127_6907405_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000001693 184.0
TLS3_k127_6907405_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000001733 169.0
TLS3_k127_6907405_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.0000000000000000000000000000000001137 141.0
TLS3_k127_6907405_8 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000004857 128.0
TLS3_k127_6907405_9 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.0000000000000000000000005258 109.0
TLS3_k127_6912904_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1181.0
TLS3_k127_6912904_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 6.381e-194 622.0
TLS3_k127_6934814_0 RecQ zinc-binding K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 443.0
TLS3_k127_6934814_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003697 224.0
TLS3_k127_6934814_2 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000001024 202.0
TLS3_k127_6934814_3 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000001251 136.0
TLS3_k127_6945533_0 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 458.0
TLS3_k127_6945533_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 410.0
TLS3_k127_6945533_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000002652 270.0
TLS3_k127_6945533_3 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000002329 211.0
TLS3_k127_6945533_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000001194 75.0
TLS3_k127_6962035_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 291.0
TLS3_k127_6962035_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001546 246.0
TLS3_k127_6962035_2 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000004774 202.0
TLS3_k127_6962035_3 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000000000000001651 147.0
TLS3_k127_6962035_4 Domain of unknown function (DUF4180) - - - 0.0000000000000000000001641 101.0
TLS3_k127_6962035_5 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000001733 76.0
TLS3_k127_696720_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1149.0
TLS3_k127_696720_1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 436.0
TLS3_k127_696720_2 Endonuclease/Exonuclease/phosphatase family - - - 0.00000004417 64.0
TLS3_k127_6972447_0 PFAM Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 365.0
TLS3_k127_6972447_1 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 364.0
TLS3_k127_6972447_2 Tetrapyrrole (Corrin/Porphyrin) Methylases K01719,K01749,K02303,K13542,K13543 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 374.0
TLS3_k127_6972447_3 sirohydrochlorin cobaltochelatase activity K03795 - 4.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000006383 264.0
TLS3_k127_6972447_4 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000007959 101.0
TLS3_k127_6979498_0 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 502.0
TLS3_k127_6979498_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000005841 226.0
TLS3_k127_6979498_2 glyoxalase K07032 - - 0.000000000000000000000000000000000000000000000000000000000000524 212.0
TLS3_k127_6979498_3 FMN binding - - - 0.000000000000000000002781 100.0
TLS3_k127_6979498_4 -acetyltransferase - - - 0.00000002914 64.0
TLS3_k127_6979498_5 Acetyltransferase (GNAT) family - - - 0.00001823 56.0
TLS3_k127_698408_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 3.655e-296 926.0
TLS3_k127_698408_1 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 5.667e-216 694.0
TLS3_k127_7016342_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1464.0
TLS3_k127_7016342_1 ERAP1-like C-terminal domain K01256,K08776 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007842 417.0
TLS3_k127_7016342_10 Acetyltransferase K22476 - 2.3.1.1 0.00002729 53.0
TLS3_k127_7016342_11 DnaJ molecular chaperone homology domain K09523 - - 0.0001232 53.0
TLS3_k127_7016342_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006008 403.0
TLS3_k127_7016342_3 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K01955,K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 391.0
TLS3_k127_7016342_4 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 365.0
TLS3_k127_7016342_5 Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000006243 218.0
TLS3_k127_7016342_6 Pfam:Pyridox_oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000491 213.0
TLS3_k127_7016342_7 TIGRFAM clan AA aspartic protease, AF_0612 family - - - 0.000000000000000000000000000000000000000000009647 166.0
TLS3_k127_7016342_8 Oxidoreductase NAD-binding domain K02823 - - 0.000000000000000000000000000000000002526 153.0
TLS3_k127_7016342_9 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000009101 121.0
TLS3_k127_703985_0 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002711 265.0
TLS3_k127_703985_1 formyl-CoA transferase activity - - - 0.00000000000000000000000000000000000000000000000000000009868 210.0
TLS3_k127_703985_2 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.0000000000000004077 91.0
TLS3_k127_703985_3 Copper binding proteins, plastocyanin/azurin family - - - 0.00003749 53.0
TLS3_k127_7103792_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 412.0
TLS3_k127_7103792_1 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 321.0
TLS3_k127_7103792_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 317.0
TLS3_k127_7103792_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001856 250.0
TLS3_k127_7103792_4 tRNA nucleotidyltransferase domain 2 putative K00970 - 2.7.7.19 0.000000000000000000000000000000002161 140.0
TLS3_k127_7103792_5 lactoylglutathione lyase activity - - - 0.000000000000000000001288 104.0
TLS3_k127_7103792_6 Preprotein translocase subunit K03210 - - 0.0000001793 57.0
TLS3_k127_71212_0 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 368.0
TLS3_k127_71212_1 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001419 280.0
TLS3_k127_71212_2 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000007714 202.0
TLS3_k127_71212_3 Aspartyl protease - - - 0.00000001459 62.0
TLS3_k127_71212_4 - - - - 0.0000004555 58.0
TLS3_k127_7123079_0 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001474 276.0
TLS3_k127_7123079_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000004659 119.0
TLS3_k127_7123079_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000003073 88.0
TLS3_k127_7131184_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 338.0
TLS3_k127_7131184_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007916 267.0
TLS3_k127_7131184_2 PFAM luciferase family protein - - - 0.00000000000000000000000000000000000000000000000000005448 198.0
TLS3_k127_7141395_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001335 256.0
TLS3_k127_7141395_1 Belongs to the LDH2 MDH2 oxidoreductase family K13574 - - 0.000007682 55.0
TLS3_k127_7175606_0 L-lactate permease K03303 - - 5.779e-206 654.0
TLS3_k127_7175606_1 metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 453.0
TLS3_k127_7175606_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 338.0
TLS3_k127_7175606_3 Nitronate monooxygenase - - - 0.000000000433 63.0
TLS3_k127_7179404_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 442.0
TLS3_k127_7179404_1 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000745 255.0
TLS3_k127_7179404_10 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000004619 57.0
TLS3_k127_7179404_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000001078 237.0
TLS3_k127_7179404_3 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000003322 189.0
TLS3_k127_7179404_4 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000005841 155.0
TLS3_k127_7179404_5 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000165 146.0
TLS3_k127_7179404_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000002868 132.0
TLS3_k127_7179404_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000006179 104.0
TLS3_k127_7179404_8 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000001203 78.0
TLS3_k127_7179404_9 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000001192 74.0
TLS3_k127_7204081_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 439.0
TLS3_k127_7204081_1 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 404.0
TLS3_k127_7204081_2 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000005285 254.0
TLS3_k127_7204081_3 CoA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000003465 215.0
TLS3_k127_7204081_4 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000007456 218.0
TLS3_k127_7204081_5 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000006325 216.0
TLS3_k127_7204081_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000001162 183.0
TLS3_k127_7204081_7 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000002536 148.0
TLS3_k127_7204081_8 polysaccharide biosynthetic process - - - 0.000000000000000000000000000001709 138.0
TLS3_k127_7204081_9 Glycosyl transferase WecB/TagA/CpsF family K05946 - 2.4.1.187 0.000000000000005172 77.0
TLS3_k127_7217330_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002965 246.0
TLS3_k127_7217330_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000002835 216.0
TLS3_k127_7217330_2 Haloacid dehalogenase-like hydrolase - GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0044237,GO:0050308,GO:0050309 - 0.000000000000000000000000000002392 129.0
TLS3_k127_7240949_0 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000001638 220.0
TLS3_k127_7240949_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000873 173.0
TLS3_k127_7240949_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000007407 162.0
TLS3_k127_7240949_3 Ferric uptake regulator family K03711 - - 0.000000000000000000000001388 107.0
TLS3_k127_7240949_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000000000005105 104.0
TLS3_k127_72433_0 elongation factor Tu domain 2 protein K06207 - - 4.557e-205 651.0
TLS3_k127_72433_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 511.0
TLS3_k127_72433_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 462.0
TLS3_k127_72433_3 Ferric reductase like transmembrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 319.0
TLS3_k127_72433_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000004781 267.0
TLS3_k127_72433_5 PFAM peptidase S1 and S6, chymotrypsin Hap K08070 - 1.3.1.74 0.000000000000000000000000000000000000000000000000000000001258 218.0
TLS3_k127_72433_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000009041 130.0
TLS3_k127_72433_7 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000002846 122.0
TLS3_k127_7246994_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 419.0
TLS3_k127_7246994_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 305.0
TLS3_k127_7246994_10 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000004665 158.0
TLS3_k127_7246994_11 Protein of unknown function (DUF402) K09145 - - 0.00000000000000000000000000000000000007779 152.0
TLS3_k127_7246994_12 protein with SCP PR1 domains - - - 0.0000000000000000000000000002409 120.0
TLS3_k127_7246994_14 - - - - 0.00000000000000000000007207 102.0
TLS3_k127_7246994_15 bis(5'-adenosyl)-triphosphatase activity - - - 0.000000000000000000003625 96.0
TLS3_k127_7246994_16 PFAM Peptidase family M23 K21471 - - 0.00000004149 64.0
TLS3_k127_7246994_17 Putative regulatory protein - - - 0.00005907 49.0
TLS3_k127_7246994_2 PFAM DAHP synthetase I K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000001015 273.0
TLS3_k127_7246994_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004796 230.0
TLS3_k127_7246994_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000001051 207.0
TLS3_k127_7246994_5 belongs to the thioredoxin family K03671,K05838 - - 0.0000000000000000000000000000000000000000000000000000000002291 217.0
TLS3_k127_7246994_6 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000003757 214.0
TLS3_k127_7246994_7 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000004632 202.0
TLS3_k127_7246994_8 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000002525 169.0
TLS3_k127_7246994_9 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000001608 157.0
TLS3_k127_7253284_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 4.376e-233 736.0
TLS3_k127_7253284_1 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000001078 276.0
TLS3_k127_7253284_10 domain protein - - - 0.0009281 50.0
TLS3_k127_7253284_2 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000000000000000000000000004905 233.0
TLS3_k127_7253284_3 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001244 228.0
TLS3_k127_7253284_4 Acetyltransferase (GNAT) domain K00657,K00663 - 2.3.1.57,2.3.1.82 0.0000000000000000000000000000000000000000006042 167.0
TLS3_k127_7253284_5 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III - - - 0.00000000000000000000000001661 123.0
TLS3_k127_7253284_6 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000004005 119.0
TLS3_k127_7253284_7 KR domain - - - 0.0000000000000001362 84.0
TLS3_k127_7253284_8 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.0000001197 55.0
TLS3_k127_7258349_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 588.0
TLS3_k127_7258349_1 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.0000000000000000000000000000000000000000000009372 185.0
TLS3_k127_7258349_2 PFAM Peptidase family M23 - - - 0.0000000000000000000000000002556 129.0
TLS3_k127_7258349_3 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000002801 62.0
TLS3_k127_7269252_0 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 304.0
TLS3_k127_7269252_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007402 284.0
TLS3_k127_7269252_10 Tetratricopeptide repeat - - - 0.00000000000000005607 91.0
TLS3_k127_7269252_11 AntiSigma factor - - - 0.000001657 59.0
TLS3_k127_7269252_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000112 192.0
TLS3_k127_7269252_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000004456 171.0
TLS3_k127_7269252_4 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000004052 167.0
TLS3_k127_7269252_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000138 158.0
TLS3_k127_7269252_6 arsR family - - - 0.00000000000000000000000000000000000000001638 155.0
TLS3_k127_7269252_7 glyoxalase III activity - - - 0.0000000000000000000000000000000000000002069 155.0
TLS3_k127_7269252_8 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000002887 169.0
TLS3_k127_7269252_9 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000009153 149.0
TLS3_k127_7312065_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 8.713e-229 715.0
TLS3_k127_7312065_1 Thi4 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 531.0
TLS3_k127_7312065_10 COG4635 Flavodoxin K00230 - 1.3.5.3 0.0000000000000000000000000000000000000000000265 168.0
TLS3_k127_7312065_11 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.00000000000000000000000000000000001184 139.0
TLS3_k127_7312065_13 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000004107 133.0
TLS3_k127_7312065_14 Small integral membrane protein - - - 0.00000000000000000000000001273 114.0
TLS3_k127_7312065_15 Domain of unknown function (DUF4287) - - - 0.000000000000000000000001732 105.0
TLS3_k127_7312065_16 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000000000001186 104.0
TLS3_k127_7312065_17 Predicted membrane protein (DUF2231) - - - 0.000000000000000000003927 100.0
TLS3_k127_7312065_18 PFAM Cysteine-rich secretory protein family - - - 0.000000000000000002845 96.0
TLS3_k127_7312065_19 - - - - 0.00000001266 61.0
TLS3_k127_7312065_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 423.0
TLS3_k127_7312065_20 Cupin domain - - - 0.000579 49.0
TLS3_k127_7312065_3 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 352.0
TLS3_k127_7312065_4 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001552 271.0
TLS3_k127_7312065_5 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008562 243.0
TLS3_k127_7312065_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000283 234.0
TLS3_k127_7312065_7 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000003485 215.0
TLS3_k127_7312065_8 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000001565 199.0
TLS3_k127_7312065_9 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.0000000000000000000000000000000000000000000000000001709 189.0
TLS3_k127_7313004_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 347.0
TLS3_k127_7313004_1 Alpha mannosidase, middle domain K01191,K15524,K16869 GO:0003674,GO:0003824,GO:0004553,GO:0004559,GO:0005975,GO:0005996,GO:0006013,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015923,GO:0016787,GO:0016798,GO:0019318,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0071704,GO:1901135,GO:1901564 2.3.1.204,3.2.1.170,3.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 306.0
TLS3_k127_7317227_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 382.0
TLS3_k127_7317227_1 PFAM Alcohol dehydrogenase, zinc-binding K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 339.0
TLS3_k127_7317227_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000233 268.0
TLS3_k127_7317227_3 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000001582 232.0
TLS3_k127_7317227_4 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000001297 219.0
TLS3_k127_7317227_5 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000009299 171.0
TLS3_k127_7317227_6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000003607 112.0
TLS3_k127_7317227_7 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000001141 99.0
TLS3_k127_7317227_8 KH domain K06960 - - 0.0000000000000000136 84.0
TLS3_k127_7317674_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 2.725e-256 812.0
TLS3_k127_7317674_1 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000006507 238.0
TLS3_k127_7317674_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000002538 222.0
TLS3_k127_7317674_3 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000002817 185.0
TLS3_k127_7317674_4 acetyltransferase - - - 0.00000000000000000000000000000000000000000000006157 173.0
TLS3_k127_7317674_5 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.0000000000000000000000000000006143 128.0
TLS3_k127_7332792_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K00058,K03977 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 433.0
TLS3_k127_7332792_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 313.0
TLS3_k127_7332792_10 protein with SCP PR1 domains - - - 0.0000000000002918 79.0
TLS3_k127_7332792_11 YbbR-like protein - - - 0.00000008756 65.0
TLS3_k127_7332792_2 ATPase with chaperone activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000202 293.0
TLS3_k127_7332792_3 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000002373 226.0
TLS3_k127_7332792_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000005283 214.0
TLS3_k127_7332792_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000006213 138.0
TLS3_k127_7332792_6 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000000000006541 142.0
TLS3_k127_7332792_7 NUDIX domain - - - 0.000000000000000000000000000000002695 136.0
TLS3_k127_7332792_8 Kelch - - - 0.0000000000000000000000004052 115.0
TLS3_k127_7332792_9 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000003621 87.0
TLS3_k127_7372423_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 6.122e-278 863.0
TLS3_k127_7372423_1 Amylo-alpha-1,6-glucosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009873 461.0
TLS3_k127_7372423_2 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004693 258.0
TLS3_k127_7372423_3 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000001028 203.0
TLS3_k127_7372423_4 4-alpha-D-((1- 4)-alpha-D-glucano)trehalose trehalohydrolase K01236 - 3.2.1.141 0.0000000000000000000000000000000000000005017 155.0
TLS3_k127_7399307_0 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 485.0
TLS3_k127_7399307_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 447.0
TLS3_k127_7399307_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 324.0
TLS3_k127_7399307_3 glucan 1,4-alpha-glucosidase activity K05989,K20541 - 3.2.1.40 0.0000000000000000000000000000000000000000002787 173.0
TLS3_k127_7399307_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000188 139.0
TLS3_k127_7399307_5 membrane K08972 - - 0.00000000000000000192 90.0
TLS3_k127_7399307_6 Domain of unknown function (DUF4388) - - - 0.0000000000000007989 88.0
TLS3_k127_7399307_7 histidine kinase HAMP region domain protein K03406 - - 0.0000006963 61.0
TLS3_k127_7399307_8 Protein of unknown function (DUF4242) - - - 0.000002799 53.0
TLS3_k127_7399307_9 Helix-turn-helix domain - - - 0.0002536 51.0
TLS3_k127_7431345_0 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 388.0
TLS3_k127_7431345_1 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000004806 238.0
TLS3_k127_760273_0 MMPL family K06994,K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 457.0
TLS3_k127_760273_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 415.0
TLS3_k127_760273_2 Transcriptional regulator, AraC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 325.0
TLS3_k127_760273_3 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 295.0
TLS3_k127_760273_4 PFAM Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001934 260.0
TLS3_k127_760273_5 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000003384 125.0
TLS3_k127_760273_6 Protein of unknown function (DUF454) K09790 - - 0.000000000000000000000000001477 119.0
TLS3_k127_760273_7 nUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.00000000004724 75.0
TLS3_k127_760273_8 EamA-like transporter family K03298 - - 0.0000000001522 73.0
TLS3_k127_760273_9 NUDIX domain - - - 0.0000000001942 73.0
TLS3_k127_7688618_0 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 337.0
TLS3_k127_7688618_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 295.0
TLS3_k127_7688618_2 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001508 282.0
TLS3_k127_7688618_3 - - - - 0.0000000000000000000000271 105.0
TLS3_k127_7688618_4 ABC-type multidrug transport system, permease component K01992 - - 0.0005146 47.0
TLS3_k127_7745255_0 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 1.329e-200 638.0
TLS3_k127_7745255_1 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 437.0
TLS3_k127_7745255_10 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000001976 178.0
TLS3_k127_7745255_11 - - - - 0.00000000000000000000000000000000000000000005527 178.0
TLS3_k127_7745255_12 HDOD domain - - - 0.0000000000000000000000000000001 136.0
TLS3_k127_7745255_13 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000001953 112.0
TLS3_k127_7745255_14 PAP2 superfamily - - - 0.00000000000000000000006141 110.0
TLS3_k127_7745255_15 cell adhesion K06236 - - 0.000000003263 70.0
TLS3_k127_7745255_16 cell adhesion - - - 0.00000001722 68.0
TLS3_k127_7745255_17 Transcriptional regulator - - - 0.000003447 59.0
TLS3_k127_7745255_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009918 369.0
TLS3_k127_7745255_3 KR domain K00059,K18337 - 1.1.1.100,1.1.1.173,1.1.1.377,1.1.1.378 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 328.0
TLS3_k127_7745255_4 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 304.0
TLS3_k127_7745255_5 Sterol carrier protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 302.0
TLS3_k127_7745255_6 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000001018 267.0
TLS3_k127_7745255_7 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003652 231.0
TLS3_k127_7745255_8 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.000000000000000000000000000000000000000000000000000000003339 209.0
TLS3_k127_7745255_9 Superoxide dismutase K00518 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000002048 188.0
TLS3_k127_7755446_0 Secreted repeat of unknown function - - - 0.000000000000000000000001716 110.0
TLS3_k127_7755446_1 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) - - - 0.00000000000000003077 91.0
TLS3_k127_7755446_2 helix_turn_helix, Lux Regulon - - - 0.000001072 59.0
TLS3_k127_7762505_0 Belongs to the sigma-70 factor family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 562.0
TLS3_k127_7762505_1 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 543.0
TLS3_k127_7762505_2 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 319.0
TLS3_k127_7762505_3 PFAM DGPFAETKE family protein - - - 0.000000000000000000000000000000000000000000000000000000008698 205.0
TLS3_k127_7762505_4 PFAM DGPFAETKE family protein - - - 0.0000000000000000000000000000000000000000000000000001909 190.0
TLS3_k127_7762505_5 protein, possibly involved in aromatic compounds catabolism K02614 - - 0.0000000000000000000000000002045 119.0
TLS3_k127_7780271_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K11177 - 1.17.1.4 2.496e-213 683.0
TLS3_k127_7780271_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009716 433.0
TLS3_k127_7780271_2 Alpha beta hydrolase K01563,K22318 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 311.0
TLS3_k127_7780271_3 COG0842 ABC-type multidrug transport system, permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003697 271.0
TLS3_k127_7796375_0 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 471.0
TLS3_k127_7796375_1 catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 440.0
TLS3_k127_7796375_2 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009955 352.0
TLS3_k127_7796375_3 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007135 282.0
TLS3_k127_7796375_4 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001273 256.0
TLS3_k127_7796375_5 Peptidase M1, membrane alanine aminopeptidase - - - 0.0000006331 63.0
TLS3_k127_7799727_0 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit K11779 - 2.5.1.77 0.0 1128.0
TLS3_k127_7799727_1 Carbamoyl-phosphate synthetase large chain domain protein K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 542.0
TLS3_k127_7799727_10 Toxic component of a toxin-antitoxin (TA) module. An RNase K19686 - - 0.0000000000000000000000000000000000000000002994 161.0
TLS3_k127_7799727_11 phosphoprotein phosphatase activity - - - 0.00000000000000000000000000000000000000004041 160.0
TLS3_k127_7799727_12 Protein of unknown function (DUF2889) K07053 - 3.1.3.97 0.000000000000000000000000000000000000002268 155.0
TLS3_k127_7799727_13 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000007375 156.0
TLS3_k127_7799727_14 G5 domain protein - - - 0.000000000000000000000000000000000000008603 162.0
TLS3_k127_7799727_15 PFAM S23 ribosomal protein - - - 0.0000000000000000000000000000000003646 135.0
TLS3_k127_7799727_16 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000001494 122.0
TLS3_k127_7799727_17 SnoaL-like domain - - - 0.00000000000000000000000001546 115.0
TLS3_k127_7799727_18 Phosphoglycerate mutase family - - - 0.00000000000000000000000001677 117.0
TLS3_k127_7799727_19 PFAM Rv0623 family protein transcription factor K19687 - - 0.00000000000000000000002516 104.0
TLS3_k127_7799727_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 546.0
TLS3_k127_7799727_20 Biotin-requiring enzyme - - - 0.00000000000008789 79.0
TLS3_k127_7799727_22 - - - - 0.0000000034 62.0
TLS3_k127_7799727_23 helix_turn_helix, Lux Regulon - - - 0.00000001314 63.0
TLS3_k127_7799727_24 - - - - 0.0000004035 58.0
TLS3_k127_7799727_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 493.0
TLS3_k127_7799727_4 AAA ATPase, central domain protein K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 437.0
TLS3_k127_7799727_5 ATPase associated with various cellular activities AAA_5 K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 362.0
TLS3_k127_7799727_6 von Willebrand factor (vWF) type A domain K02448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 346.0
TLS3_k127_7799727_7 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 322.0
TLS3_k127_7799727_8 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000004199 207.0
TLS3_k127_7799727_9 Bifunctional coenzyme A synthase K02318 GO:0000003,GO:0001667,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002165,GO:0003006,GO:0003674,GO:0003824,GO:0004140,GO:0004595,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005759,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006928,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007300,GO:0007303,GO:0007444,GO:0007472,GO:0007476,GO:0007552,GO:0007560,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0009987,GO:0010631,GO:0015936,GO:0015937,GO:0016020,GO:0016301,GO:0016310,GO:0016477,GO:0016482,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019867,GO:0019953,GO:0022412,GO:0022414,GO:0030154,GO:0030707,GO:0030855,GO:0031090,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040011,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0046390,GO:0046483,GO:0046907,GO:0048468,GO:0048477,GO:0048513,GO:0048563,GO:0048569,GO:0048609,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0048869,GO:0048870,GO:0048878,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0055086,GO:0055088,GO:0055090,GO:0060429,GO:0060562,GO:0065007,GO:0065008,GO:0070013,GO:0070328,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090130,GO:0090132,GO:0090407,GO:0098588,GO:0098805,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24,2.7.7.3 0.000000000000000000000000000000000000000000000001038 187.0
TLS3_k127_7811605_0 carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 378.0
TLS3_k127_7811605_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 302.0
TLS3_k127_7811605_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000115 256.0
TLS3_k127_7811605_3 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000005105 188.0
TLS3_k127_7811605_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000001281 181.0
TLS3_k127_7811605_5 PA domain K19701 - 3.4.11.10,3.4.11.6 0.000000000000000000000000000000000000000000001705 182.0
TLS3_k127_7811605_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000001501 130.0
TLS3_k127_7811605_7 Rdx family K07401 - - 0.0000000000000000005673 92.0
TLS3_k127_7811605_8 Lysin motif - - - 0.000000006531 65.0
TLS3_k127_7815865_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.145e-261 839.0
TLS3_k127_7815865_1 cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000001319 219.0
TLS3_k127_7815865_2 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.00000000000007643 85.0
TLS3_k127_7829560_0 Thi4 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001803 252.0
TLS3_k127_7829560_1 PKD domain - - - 0.000000000000000004318 99.0
TLS3_k127_7859587_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 2.063e-230 717.0
TLS3_k127_7859587_1 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 323.0
TLS3_k127_7859587_2 CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000145 277.0
TLS3_k127_7859587_3 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000008773 199.0
TLS3_k127_7859587_4 hydrolase K07025 - - 0.00000000000000000000000000000000000007422 153.0
TLS3_k127_7859587_5 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000549 89.0
TLS3_k127_7859587_6 Protein of unknown function (DUF433) - - - 0.000000000002633 70.0
TLS3_k127_7859587_7 - - - - 0.00000000001099 70.0
TLS3_k127_7876109_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.525e-220 700.0
TLS3_k127_7876109_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 6.508e-210 663.0
TLS3_k127_7876109_10 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 320.0
TLS3_k127_7876109_11 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 311.0
TLS3_k127_7876109_12 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009853 284.0
TLS3_k127_7876109_13 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009557 278.0
TLS3_k127_7876109_14 Amidinotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001147 271.0
TLS3_k127_7876109_15 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573,K03183,K07003 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259 2.1.1.163,2.1.1.201,2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000001852 274.0
TLS3_k127_7876109_16 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000001569 216.0
TLS3_k127_7876109_17 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000003171 207.0
TLS3_k127_7876109_18 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000002172 207.0
TLS3_k127_7876109_19 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000002 191.0
TLS3_k127_7876109_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 598.0
TLS3_k127_7876109_20 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000031 181.0
TLS3_k127_7876109_21 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000001046 167.0
TLS3_k127_7876109_22 THIoesterase K18700 - 3.1.2.29 0.0000000000000000000003994 102.0
TLS3_k127_7876109_23 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000002873 89.0
TLS3_k127_7876109_24 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000002786 82.0
TLS3_k127_7876109_26 Cupredoxin-like domain - - - 0.000000006915 62.0
TLS3_k127_7876109_27 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000008651 59.0
TLS3_k127_7876109_28 - - - - 0.0001148 53.0
TLS3_k127_7876109_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 525.0
TLS3_k127_7876109_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 489.0
TLS3_k127_7876109_5 aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 480.0
TLS3_k127_7876109_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 464.0
TLS3_k127_7876109_7 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 406.0
TLS3_k127_7876109_8 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005169 366.0
TLS3_k127_7876109_9 SAICAR synthetase K01923,K01945,K03566 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 335.0
TLS3_k127_7879242_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K11177 - 1.17.1.4 1.664e-290 913.0
TLS3_k127_7879242_1 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003316 301.0
TLS3_k127_7879242_2 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000003572 234.0
TLS3_k127_7879242_3 COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519,K11178 - 1.17.1.4,1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001598 241.0
TLS3_k127_7879242_4 -phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000005319 126.0
TLS3_k127_7879242_5 ThiS family K03636 - - 0.000000004176 60.0
TLS3_k127_7879242_6 domain, Protein - - - 0.000002715 56.0
TLS3_k127_789083_0 Carboxyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 390.0
TLS3_k127_789083_1 Endoglucanase K01179 - 3.2.1.4 0.00000000000000000000000000001243 134.0
TLS3_k127_7901468_0 PFAM Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 412.0
TLS3_k127_7901468_1 Prolyl oligopeptidase family K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000125 227.0
TLS3_k127_7933059_0 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 404.0
TLS3_k127_7933059_1 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000007253 186.0
TLS3_k127_7937294_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 469.0
TLS3_k127_7937294_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 415.0
TLS3_k127_7958697_0 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 515.0
TLS3_k127_7958697_1 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 347.0
TLS3_k127_7958697_10 glycosyl transferase family 2 - - - 0.00000000000000000000000000000002038 141.0
TLS3_k127_7958697_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000803 106.0
TLS3_k127_7958697_12 - - - - 0.00000000000000000000001383 102.0
TLS3_k127_7958697_13 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000004348 105.0
TLS3_k127_7958697_14 Belongs to the bacterial ribosomal protein bL33 family K02913 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000005922 70.0
TLS3_k127_7958697_15 Carotene biosynthesis associated membrane protein K14337,K14339 - - 0.0000000002167 73.0
TLS3_k127_7958697_16 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00000003083 66.0
TLS3_k127_7958697_17 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00003138 53.0
TLS3_k127_7958697_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 293.0
TLS3_k127_7958697_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002588 265.0
TLS3_k127_7958697_4 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000002729 224.0
TLS3_k127_7958697_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000002099 210.0
TLS3_k127_7958697_6 Protein of unknown function (DUF998) - - - 0.00000000000000000000000000000000000000000000000003151 188.0
TLS3_k127_7958697_7 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000002908 186.0
TLS3_k127_7958697_8 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000401 181.0
TLS3_k127_7958697_9 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000004653 143.0
TLS3_k127_7981779_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 451.0
TLS3_k127_7981779_1 elongation factor G K18220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007263 264.0
TLS3_k127_7981779_10 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000001281 104.0
TLS3_k127_7981779_11 MOSC domain - - - 0.00000000000000112 78.0
TLS3_k127_7981779_12 Protein of unknown function (DUF1761) - - - 0.000000000009369 70.0
TLS3_k127_7981779_2 carboxylic ester hydrolase activity K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000002239 234.0
TLS3_k127_7981779_3 Belongs to the peptidase S1B family - - - 0.000000000000000000000000000000000000000000000000000000002125 210.0
TLS3_k127_7981779_4 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000000004638 205.0
TLS3_k127_7981779_5 stress protein (general stress protein 26) - - - 0.000000000000000000000000000000000000000001194 160.0
TLS3_k127_7981779_6 arsR family - - - 0.00000000000000000000000000000006662 128.0
TLS3_k127_7981779_7 coenzyme F420 binding - - - 0.00000000000000000000000000002056 124.0
TLS3_k127_7981779_8 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000004422 120.0
TLS3_k127_7981779_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000007145 106.0
TLS3_k127_7982435_0 Flavoprotein involved in K transport - - - 3.194e-280 866.0
TLS3_k127_7982435_1 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 617.0
TLS3_k127_7982435_2 Nad-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 381.0
TLS3_k127_7982435_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 307.0
TLS3_k127_7982435_4 NADPH-dependent FMN reductase K00299 - 1.5.1.38 0.000000000000000000000000000000000000000000000000003323 192.0
TLS3_k127_7982435_5 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000001168 120.0
TLS3_k127_7982435_6 MFS/sugar transport protein - - - 0.000000000000000000000000003876 125.0
TLS3_k127_7982435_7 hemerythrin HHE cation binding domain - - - 0.00008974 52.0
TLS3_k127_8007746_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000004616 163.0
TLS3_k127_8007746_1 Phosphohydrolase-associated domain K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000001334 101.0
TLS3_k127_8007746_2 sh3 domain protein K01448,K04771,K08884 - 2.7.11.1,3.4.21.107,3.5.1.28 0.0006336 52.0
TLS3_k127_8038631_0 helix_turn_helix, Lux Regulon - - - 1.432e-218 700.0
TLS3_k127_8039567_0 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 378.0
TLS3_k127_8039567_1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000006967 155.0
TLS3_k127_8039567_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000003037 119.0
TLS3_k127_8039567_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000372 100.0
TLS3_k127_8097070_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.424e-217 686.0
TLS3_k127_8097070_1 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 430.0
TLS3_k127_8097070_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 347.0
TLS3_k127_8097070_3 Trypsin-like serine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008787 316.0
TLS3_k127_8097070_4 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000001033 196.0
TLS3_k127_8097070_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K20459 - - 0.00000000000000000000000000000000000000000000000001022 193.0
TLS3_k127_8097070_6 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000001219 169.0
TLS3_k127_8097070_7 reversible hydration of carbon dioxide - - - 0.00000000000003212 79.0
TLS3_k127_8097070_8 helix_turn_helix, Lux Regulon - - - 0.00000004156 64.0
TLS3_k127_8097070_9 Phosphotriesterase family K07048 - - 0.00001818 50.0
TLS3_k127_8120199_0 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003753 239.0
TLS3_k127_8120199_1 AzlC protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003223 227.0
TLS3_k127_8120199_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000006976 147.0
TLS3_k127_8120199_4 transcriptional regulator - - - 0.00004051 55.0
TLS3_k127_8121139_0 alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 565.0
TLS3_k127_8121139_1 PFAM MgtC SapB transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 376.0
TLS3_k127_8121139_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000468 288.0
TLS3_k127_8121139_3 Aminoglycoside/hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001813 277.0
TLS3_k127_8121139_4 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000616 202.0
TLS3_k127_8121139_5 PFAM DSBA oxidoreductase - - - 0.0000000000000000000000000005049 122.0
TLS3_k127_8121139_6 Dodecin - - - 0.00000000000000000000007031 101.0
TLS3_k127_8121139_7 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00001047 60.0
TLS3_k127_8121139_8 histidine kinase A domain protein - - - 0.00002386 59.0
TLS3_k127_8159397_0 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K00657,K07023 - 2.3.1.57 0.000000000000000000000000000000000000000000000000000000007461 203.0
TLS3_k127_8159397_1 copper resistance D domain protein K14166 - - 0.000000000000000000000000000000000000009657 166.0
TLS3_k127_8159397_2 - - - - 0.0000000000008742 76.0
TLS3_k127_8159397_3 cytochrome c K00405,K07245 - - 0.000000005013 70.0
TLS3_k127_8159397_4 CopC domain K07156,K14166 - - 0.000000743 59.0
TLS3_k127_8175695_0 Nitrite and sulphite reductase 4Fe-4S domain K00366,K00381 - 1.7.7.1,1.8.1.2 1.061e-241 759.0
TLS3_k127_8175695_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 467.0
TLS3_k127_8175695_2 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 440.0
TLS3_k127_8175695_3 Belongs to the PAPS reductase family. CysH subfamily K00390,K00860 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8,2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000001951 268.0
TLS3_k127_8175695_4 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000003056 228.0
TLS3_k127_8175695_5 Na+/Pi-cotransporter - - - 0.000000000000000000000000000000000000000000000000004591 192.0
TLS3_k127_8194985_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000322 250.0
TLS3_k127_8217907_0 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 367.0
TLS3_k127_8217907_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 366.0
TLS3_k127_8217907_10 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000003846 96.0
TLS3_k127_8217907_11 Protein of unknown function (DUF664) - - - 0.00000000000000001654 91.0
TLS3_k127_8217907_12 Universal stress protein family - - - 0.0000000000003489 76.0
TLS3_k127_8217907_13 Protein of unknown function (DUF1697) - - - 0.0000000000005587 76.0
TLS3_k127_8217907_14 PAC2 family - - - 0.0000000118 59.0
TLS3_k127_8217907_15 Domain of unknown function DUF11 - - - 0.0000002596 64.0
TLS3_k127_8217907_2 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 334.0
TLS3_k127_8217907_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006811 246.0
TLS3_k127_8217907_4 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000001079 244.0
TLS3_k127_8217907_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000002041 218.0
TLS3_k127_8217907_6 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000003073 171.0
TLS3_k127_8217907_7 Limonene-1,2-epoxide hydrolase - - - 0.0000000000000000000000000000000000000006677 152.0
TLS3_k127_8217907_8 - - - - 0.000000000000000000000000000000007266 132.0
TLS3_k127_8217907_9 Tyrosine phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000003397 122.0
TLS3_k127_8240959_0 Prolyl oligopeptidase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000189 243.0
TLS3_k127_8240959_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000002411 222.0
TLS3_k127_8268310_0 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000001252 224.0
TLS3_k127_8268310_1 soluble inorganic pyrophosphatase K01507 GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 3.6.1.1 0.0000000000000000000000000000000000000000000000000000003878 205.0
TLS3_k127_8268310_2 Cobalt transport protein K16785 - - 0.0000000000000000000000000000000000007691 153.0
TLS3_k127_8268310_3 - - - - 0.000000000000000000000000000175 122.0
TLS3_k127_8268310_4 Prenyltransferase and squalene oxidase repeat - - - 0.0000000000000000000000000483 121.0
TLS3_k127_8268310_5 MobA-like NTP transferase domain K07281,K07291 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0016780 2.7.7.74,2.7.8.34 0.0000000000000000000000006014 113.0
TLS3_k127_8268310_6 pathogenesis - - - 0.0000000000000000001829 104.0
TLS3_k127_8268310_7 MobA-like NTP transferase domain K07281 - 2.7.7.74 0.00000000000001494 79.0
TLS3_k127_8276203_0 NTF2-like N-terminal transpeptidase domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001901 282.0
TLS3_k127_8276203_1 Protein of unknown function (DUF1679) - - - 0.00000000000000000000000000000000000000000000000000000000001238 221.0
TLS3_k127_8276203_2 - - - - 0.00000000000000000000000000000000000000000000044 173.0
TLS3_k127_8276203_3 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000001462 155.0
TLS3_k127_8276203_4 Enoyl-CoA hydratase K01692,K18383 - 4.1.2.41,4.2.1.101,4.2.1.17 0.000000000000000000299 95.0
TLS3_k127_8276203_5 FAD dependent oxidoreductase - - - 0.0001665 45.0
TLS3_k127_827736_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 460.0
TLS3_k127_827736_1 PFAM aminotransferase, class I K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 460.0
TLS3_k127_827736_10 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000006709 147.0
TLS3_k127_827736_12 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000003286 124.0
TLS3_k127_827736_13 Trehalose utilisation K09992 - - 0.00000000000000000000000003872 118.0
TLS3_k127_827736_14 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000002123 91.0
TLS3_k127_827736_15 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K05606 - 4.4.1.5,5.1.99.1 0.00000000000000001297 91.0
TLS3_k127_827736_16 transcriptional regulator - - - 0.000000000000000466 85.0
TLS3_k127_827736_17 Protein of unknown function (DUF1679) - - - 0.0000000005868 64.0
TLS3_k127_827736_18 Copper binding proteins, plastocyanin/azurin family - - - 0.00000001111 66.0
TLS3_k127_827736_19 - - - - 0.00009968 53.0
TLS3_k127_827736_2 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 361.0
TLS3_k127_827736_20 PFAM Sporulation and spore germination - - - 0.0002182 53.0
TLS3_k127_827736_3 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 354.0
TLS3_k127_827736_4 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 332.0
TLS3_k127_827736_5 PFAM GTP cyclohydrolase I Nitrile oxidoreductase K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000004217 241.0
TLS3_k127_827736_6 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000001088 227.0
TLS3_k127_827736_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000001498 224.0
TLS3_k127_827736_8 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000000000000005548 223.0
TLS3_k127_827736_9 - - - - 0.000000000000000000000000000000000000003091 158.0
TLS3_k127_8283105_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 297.0
TLS3_k127_8283105_1 CheR methyltransferase, SAM binding domain protein K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000007053 177.0
TLS3_k127_8283105_2 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000001444 150.0
TLS3_k127_8283105_3 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000003004 128.0
TLS3_k127_8283105_4 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.000000000000000000000000009765 117.0
TLS3_k127_8312087_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 485.0
TLS3_k127_8312087_1 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000008216 227.0
TLS3_k127_8312087_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000133 174.0
TLS3_k127_8312087_3 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.000000000000000000000000006906 119.0
TLS3_k127_8312087_4 Protein of unknown function (DUF1706) - - - 0.0000000002 67.0
TLS3_k127_8312087_5 Required for chromosome condensation and partitioning K03529 - - 0.0000000546 55.0
TLS3_k127_8357029_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000003728 248.0
TLS3_k127_8357029_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000002565 231.0
TLS3_k127_8357029_2 bacterial-type flagellum-dependent cell motility K02390 GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - 0.00000000000000000000000000000000000000000008252 165.0
TLS3_k127_8357029_3 Cytochrome D1 heme domain - - - 0.000000000000000002193 97.0
TLS3_k127_8357029_4 ABC-type dipeptide transport system periplasmic component K02035 - - 0.0000000002703 70.0
TLS3_k127_8368577_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000001087 233.0
TLS3_k127_8368577_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000883 205.0
TLS3_k127_8368577_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000007604 213.0
TLS3_k127_8368577_3 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000002722 103.0
TLS3_k127_8413180_0 Aminotransferase class I and II K10206 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 523.0
TLS3_k127_8413180_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 385.0
TLS3_k127_8413180_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 326.0
TLS3_k127_8413180_3 fad dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000003862 214.0
TLS3_k127_8413180_4 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000001024 196.0
TLS3_k127_8413180_5 Helix-turn-helix XRE-family like proteins K21498 - - 0.000000000000000000000000000000003941 132.0
TLS3_k127_8413180_6 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000000000000000006024 106.0
TLS3_k127_8413180_7 PFAM L-carnitine dehydratase bile acid-inducible protein F K07544,K07749 - 2.8.3.15,2.8.3.16 0.0000009963 51.0
TLS3_k127_8413180_8 COG2133 Glucose sorbosone dehydrogenases - - - 0.000001887 59.0
TLS3_k127_8413180_9 helix_turn_helix, Lux Regulon K07782 - - 0.00003795 56.0
TLS3_k127_8432491_0 succinate dehydrogenase K00239,K00278 - 1.3.5.1,1.3.5.4,1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 499.0
TLS3_k127_8432491_1 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004105 376.0
TLS3_k127_8432491_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 308.0
TLS3_k127_8436739_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 589.0
TLS3_k127_8436739_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 400.0
TLS3_k127_8436739_10 histidine kinase A domain protein K07646 - 2.7.13.3 0.00000000000000000000000000000002039 136.0
TLS3_k127_8436739_11 Alpha/beta hydrolase family - - - 0.00000000000000000000000491 104.0
TLS3_k127_8436739_12 DNA-binding transcription factor activity - - - 0.000000000000000000001589 97.0
TLS3_k127_8436739_13 Lactoylglutathione lyase and related lyases - - - 0.000000008854 62.0
TLS3_k127_8436739_14 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000001161 64.0
TLS3_k127_8436739_15 PFAM major facilitator superfamily MFS_1 - - - 0.0000001934 63.0
TLS3_k127_8436739_16 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00001001 53.0
TLS3_k127_8436739_2 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 377.0
TLS3_k127_8436739_3 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 312.0
TLS3_k127_8436739_4 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 296.0
TLS3_k127_8436739_5 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000001415 230.0
TLS3_k127_8436739_6 Histidine phosphatase superfamily (branch 1) K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000001939 230.0
TLS3_k127_8436739_7 PFAM Cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000002854 163.0
TLS3_k127_8436739_8 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000009973 158.0
TLS3_k127_8436739_9 nUDIX hydrolase - - - 0.00000000000000000000000000000000005463 141.0
TLS3_k127_8497129_0 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 0.00000000000000000000001497 117.0
TLS3_k127_8497129_1 FtsX-like permease family K02004 - - 0.000008556 57.0
TLS3_k127_8508467_0 NAD synthase K01916 - 6.3.1.5 1.616e-194 623.0
TLS3_k127_8508467_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 441.0
TLS3_k127_8508467_2 Nitroreductase family - - - 0.00000000000000000000000000005948 123.0
TLS3_k127_8508467_3 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.00000000000000000000002021 107.0
TLS3_k127_8508467_4 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000105 102.0
TLS3_k127_8508467_5 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000001324 82.0
TLS3_k127_8508467_6 Protein of unknown function (DUF2283) - - - 0.0000000000004701 70.0
TLS3_k127_8521875_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 2.025e-283 896.0
TLS3_k127_8581350_0 gluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002251 278.0
TLS3_k127_8581350_1 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000005906 226.0
TLS3_k127_8581350_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000000000000000000000000000000000000216 171.0
TLS3_k127_8581350_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000001775 132.0
TLS3_k127_8581350_4 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000000000000003497 115.0
TLS3_k127_87454_0 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006033 274.0
TLS3_k127_87454_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000002405 100.0
TLS3_k127_87454_2 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000005805 81.0
TLS3_k127_884309_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 8.936e-262 824.0
TLS3_k127_884309_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 305.0
TLS3_k127_884309_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001188 283.0
TLS3_k127_884309_3 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000004718 231.0
TLS3_k127_884309_4 Acetyl-CoA hydrolase/transferase N-terminal domain K18122 - - 0.00000000000000000000000000000000000000000000000000000000001565 224.0
TLS3_k127_884309_5 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000004129 215.0
TLS3_k127_884309_6 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000001075 178.0
TLS3_k127_884309_7 COG1352 Methylase of chemotaxis methyl-accepting proteins K00575 - 2.1.1.80 0.0000000000000000000001089 99.0
TLS3_k127_884309_8 AraC-like ligand binding domain - - - 0.00000000000000009368 86.0
TLS3_k127_888588_0 PFAM molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 374.0
TLS3_k127_888588_1 PFAM amidohydrolase 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 317.0
TLS3_k127_888588_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 306.0
TLS3_k127_8945_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000004347 231.0
TLS3_k127_8945_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000002933 189.0
TLS3_k127_8945_2 - - - - 0.00000000000000000000000000000000001552 149.0
TLS3_k127_8945_3 SnoaL-like polyketide cyclase - - - 0.000000004948 62.0
TLS3_k127_912581_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 493.0
TLS3_k127_912581_1 Carboxyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 339.0
TLS3_k127_91809_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 620.0
TLS3_k127_91809_1 3-demethylubiquinone-9 3-O-methyltransferase activity K13611,K13612,K13613,K15675,K15676,K18827 - 2.1.1.294,2.7.1.181 0.00000000000000000000000000000000000000000000000005658 188.0
TLS3_k127_970637_0 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 347.0
TLS3_k127_970637_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 330.0
TLS3_k127_970637_2 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000007808 246.0
TLS3_k127_970637_3 carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000004151 233.0
TLS3_k127_970637_4 CoA-transferase family III K07543 - 2.8.3.15 0.00000000000000000000000000000000000000005042 165.0
TLS3_k127_970637_5 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000006387 147.0
TLS3_k127_970637_6 Putative TM nitroreductase - - - 0.000000000000005213 85.0
TLS3_k127_970637_7 Phage integrase family - - - 0.00000000001005 70.0
TLS3_k127_977052_0 Peptidase family M3 K01392 - 3.4.24.15 3.202e-223 709.0
TLS3_k127_977052_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 325.0
TLS3_k127_977052_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 321.0
TLS3_k127_977052_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006478 277.0
TLS3_k127_977052_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000001982 207.0
TLS3_k127_977052_5 - - - - 0.00000000000000000000003578 101.0
TLS3_k127_977052_6 thiamine pyrophosphate binding K12261 GO:0001561,GO:0003674,GO:0003824,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015031,GO:0015833,GO:0016042,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0019395,GO:0019752,GO:0019842,GO:0022607,GO:0030258,GO:0030976,GO:0031907,GO:0031974,GO:0032787,GO:0033036,GO:0033365,GO:0034440,GO:0034613,GO:0036094,GO:0042579,GO:0042802,GO:0042886,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046907,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0051259,GO:0051641,GO:0051649,GO:0055114,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072329,GO:0072594,GO:0072662,GO:0072663,GO:0097159,GO:1901363,GO:1901575,GO:1901681 - 0.000000000000000002443 87.0
TLS3_k127_977052_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000002884 64.0
TLS3_k127_977052_8 - - - - 0.0000003937 58.0
TLS3_k127_977052_9 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 0.0008097 47.0