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Overview

ID MAG04040
Name TLS3_bin.16
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Actinomycetota
Class Acidimicrobiia
Order Acidimicrobiales
Family Ilumatobacteraceae
Genus Sva-07
Species
Assembly information
Completeness (%) 94.14
Contamination (%) 1.04
GC content (%) 70.0
N50 (bp) 24,461
Genome size (bp) 3,679,342

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3354

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_101601_0 thiolester hydrolase activity K01990,K06889 GO:0008150,GO:0009987,GO:0051301 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 417.0
TLS3_k127_101601_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 394.0
TLS3_k127_101601_2 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001079 253.0
TLS3_k127_1022752_0 Periplasmic binding protein K01999 - - 7.93e-206 655.0
TLS3_k127_1022752_1 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009072 599.0
TLS3_k127_1022752_10 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001621 269.0
TLS3_k127_1022752_11 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000004278 227.0
TLS3_k127_1022752_12 beta-lactamase domain protein K13075 - 3.1.1.81 0.000000000000000000000000000000000002552 151.0
TLS3_k127_1022752_13 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000007997 134.0
TLS3_k127_1022752_14 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000001165 114.0
TLS3_k127_1022752_15 AP endonuclease family 2 C terminus - - - 0.00000000000000003217 95.0
TLS3_k127_1022752_16 - - - - 0.00000000000009936 78.0
TLS3_k127_1022752_2 Belongs to the UPF0261 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 488.0
TLS3_k127_1022752_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008105 457.0
TLS3_k127_1022752_4 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 411.0
TLS3_k127_1022752_5 Phosphoenolpyruvate hydrolase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 426.0
TLS3_k127_1022752_6 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 359.0
TLS3_k127_1022752_7 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006719 342.0
TLS3_k127_1022752_8 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 327.0
TLS3_k127_1022752_9 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001385 278.0
TLS3_k127_107263_0 Alpha beta hydrolase K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 499.0
TLS3_k127_107263_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 305.0
TLS3_k127_107263_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000002872 102.0
TLS3_k127_1084242_0 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 517.0
TLS3_k127_1084242_1 Cupin domain - - - 0.0000000000000000000000000005756 117.0
TLS3_k127_1084242_2 PFAM Methyltransferase type 11 - - - 0.00000000000002628 76.0
TLS3_k127_109728_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 5.353e-210 670.0
TLS3_k127_109728_1 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 575.0
TLS3_k127_109728_2 FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 317.0
TLS3_k127_109728_3 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003555 274.0
TLS3_k127_109728_4 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000004745 245.0
TLS3_k127_109728_5 Periplasmic binding protein domain K10543 - - 0.00000000000000000000000000000001195 132.0
TLS3_k127_1199316_0 Pyridoxal-phosphate dependent enzyme K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 581.0
TLS3_k127_1199316_1 Carboxylesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006915 478.0
TLS3_k127_1199316_2 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 293.0
TLS3_k127_1199316_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008745 289.0
TLS3_k127_1199316_4 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009968 277.0
TLS3_k127_1199316_5 JAB/MPN domain K21140 - 3.13.1.6 0.000000000000000000000000000000000000000000000000000001431 196.0
TLS3_k127_1199316_6 PFAM alpha beta hydrolase - - - 0.00000000000000000000000000000000002102 147.0
TLS3_k127_1214266_0 acyl-CoA dehydrogenase - - - 1.289e-230 716.0
TLS3_k127_1214266_1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 562.0
TLS3_k127_1214266_2 ammonium transporteR K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 427.0
TLS3_k127_1214266_3 Belongs to the P(II) protein family K04751 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000002983 183.0
TLS3_k127_1216858_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.0 1379.0
TLS3_k127_1233654_0 endonuclease activity K07451 - - 0.000000000000000000000000000000000000003419 153.0
TLS3_k127_1233654_1 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000272 106.0
TLS3_k127_1256626_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1572.0
TLS3_k127_1256626_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000002547 103.0
TLS3_k127_1256626_2 HhH-GPD superfamily base excision DNA repair protein - - - 0.0000000002601 61.0
TLS3_k127_1256626_3 - - - - 0.000002965 60.0
TLS3_k127_12913_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 356.0
TLS3_k127_12913_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000002101 59.0
TLS3_k127_1316023_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 365.0
TLS3_k127_1316023_1 Belongs to the binding-protein-dependent transport system permease family K10544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 365.0
TLS3_k127_1316023_2 ABC transporter K10545 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 340.0
TLS3_k127_1316023_3 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000005633 210.0
TLS3_k127_1316023_4 Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000000000822 174.0
TLS3_k127_1320817_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 3.151e-278 863.0
TLS3_k127_1320817_1 Predicted membrane protein (DUF2079) K07778 - 2.7.13.3 5.384e-212 670.0
TLS3_k127_1320817_10 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000008571 164.0
TLS3_k127_1320817_11 Lanthionine synthetase C family protein - - - 0.000000000000000000000000000000000000000002679 165.0
TLS3_k127_1320817_12 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000001984 139.0
TLS3_k127_1320817_13 2'-5' RNA ligase superfamily - - - 0.0000000000000000006716 94.0
TLS3_k127_1320817_14 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00008354 49.0
TLS3_k127_1320817_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 1.673e-209 675.0
TLS3_k127_1320817_3 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 554.0
TLS3_k127_1320817_4 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 483.0
TLS3_k127_1320817_5 Castor and Pollux, part of voltage-gated ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 491.0
TLS3_k127_1320817_6 Domain of unknown function (DUF222) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001769 276.0
TLS3_k127_1320817_7 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001351 264.0
TLS3_k127_1320817_8 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001061 255.0
TLS3_k127_1320817_9 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000019 192.0
TLS3_k127_1322257_0 VWA domain containing CoxE-like protein K07161 - - 1.635e-283 874.0
TLS3_k127_1322257_1 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 1.025e-274 858.0
TLS3_k127_1322257_2 Peptidase family S51 K05995 - 3.4.13.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 289.0
TLS3_k127_1322257_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000003568 246.0
TLS3_k127_1322257_4 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000001103 189.0
TLS3_k127_1322257_5 anaphase-promoting complex binding - - - 0.000000000000001259 90.0
TLS3_k127_1416129_0 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 4.515e-296 926.0
TLS3_k127_1416129_1 Methyltransferase domain K13307 - 2.1.1.235 0.00000000000000000000000000000000000000000000000000000000005042 214.0
TLS3_k127_1416129_2 adenylate kinase activity - - - 0.0000000000000000000000000000000000000000000000001181 184.0
TLS3_k127_1416129_3 Transcriptional regulator, TraR DksA family - - - 0.0000000000000000000000000000009437 125.0
TLS3_k127_1416129_4 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000005637 81.0
TLS3_k127_1416129_5 - - - - 0.000000000007246 67.0
TLS3_k127_14924_0 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 1.095e-271 850.0
TLS3_k127_14924_1 Alkyl sulfatase dimerisation - - - 0.00000000000000000000000000000000000000000000000000000000000005126 215.0
TLS3_k127_1614734_0 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 358.0
TLS3_k127_1614734_1 Sulfate permease family K03321 - - 0.000000000000000000000000011 113.0
TLS3_k127_1722374_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1589.0
TLS3_k127_1722374_1 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1121.0
TLS3_k127_1722374_10 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 9.871e-215 686.0
TLS3_k127_1722374_100 - - - - 0.0000000001028 74.0
TLS3_k127_1722374_101 COG0500 SAM-dependent methyltransferases - - - 0.00000001187 57.0
TLS3_k127_1722374_102 - - - - 0.0000421 55.0
TLS3_k127_1722374_103 peptidase activity - - - 0.0001318 46.0
TLS3_k127_1722374_104 Peptidoglycan-binding domain 1 protein - - - 0.000199 53.0
TLS3_k127_1722374_11 Transporter associated domain K03699 - - 1.395e-214 675.0
TLS3_k127_1722374_12 Carboxyl transferase domain - - - 1.847e-210 671.0
TLS3_k127_1722374_13 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.127e-208 653.0
TLS3_k127_1722374_14 Acyl transferase domain K00645 - 2.3.1.39 1.981e-200 630.0
TLS3_k127_1722374_15 Transporter associated domain - - - 5.24e-200 633.0
TLS3_k127_1722374_16 CoA-transferase family III K01796 - 5.1.99.4 3.633e-195 617.0
TLS3_k127_1722374_17 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 627.0
TLS3_k127_1722374_18 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 616.0
TLS3_k127_1722374_19 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006558 593.0
TLS3_k127_1722374_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1036.0
TLS3_k127_1722374_20 ComEC Rec2-related protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 593.0
TLS3_k127_1722374_21 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 574.0
TLS3_k127_1722374_22 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 566.0
TLS3_k127_1722374_23 competence protein COMEC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 597.0
TLS3_k127_1722374_24 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 563.0
TLS3_k127_1722374_25 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 573.0
TLS3_k127_1722374_26 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 544.0
TLS3_k127_1722374_27 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 547.0
TLS3_k127_1722374_28 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 497.0
TLS3_k127_1722374_29 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 494.0
TLS3_k127_1722374_3 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 3.831e-319 999.0
TLS3_k127_1722374_30 unsaturated fatty acid biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 485.0
TLS3_k127_1722374_31 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 473.0
TLS3_k127_1722374_32 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 476.0
TLS3_k127_1722374_33 Cytochrome b K03891 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 484.0
TLS3_k127_1722374_34 Belongs to the bacterial solute-binding protein 9 family K09818 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 468.0
TLS3_k127_1722374_35 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 458.0
TLS3_k127_1722374_36 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 448.0
TLS3_k127_1722374_37 dioxygenase K11159 GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008300,GO:0009056,GO:0009987,GO:0010436,GO:0016042,GO:0016108,GO:0016110,GO:0016115,GO:0016116,GO:0016118,GO:0016491,GO:0016701,GO:0016702,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0051213,GO:0055114,GO:0071704,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 439.0
TLS3_k127_1722374_38 dna polymerase III delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 432.0
TLS3_k127_1722374_39 ABC-type Mn2 Zn2 transport systems permease components K09819,K11602,K19975,K19976 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 426.0
TLS3_k127_1722374_4 PFAM AMP-dependent synthetase and ligase K00666,K01909 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008922,GO:0009058,GO:0009987,GO:0015645,GO:0016020,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016874,GO:0016877,GO:0016878,GO:0017076,GO:0019752,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0051704,GO:0070566,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 6.2.1.20 1.367e-313 973.0
TLS3_k127_1722374_40 LysM domain K01449 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 423.0
TLS3_k127_1722374_41 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000792 424.0
TLS3_k127_1722374_42 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 411.0
TLS3_k127_1722374_43 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005444 410.0
TLS3_k127_1722374_44 PAC2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 396.0
TLS3_k127_1722374_45 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 382.0
TLS3_k127_1722374_46 ABC transporter K09820,K11710,K19973 - 3.6.3.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 376.0
TLS3_k127_1722374_47 Tetratricopeptide repeat K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 370.0
TLS3_k127_1722374_48 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 363.0
TLS3_k127_1722374_49 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 376.0
TLS3_k127_1722374_5 Ribosomal protein S1-like RNA-binding domain K02945 - - 2.81e-252 785.0
TLS3_k127_1722374_50 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000613 356.0
TLS3_k127_1722374_51 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 353.0
TLS3_k127_1722374_52 abc transporter atp-binding protein K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 352.0
TLS3_k127_1722374_53 hydrolase activity, acting on ester bonds K01561 - 3.8.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 340.0
TLS3_k127_1722374_54 ANTAR K22010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 328.0
TLS3_k127_1722374_55 Belongs to the peptidase S51 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 340.0
TLS3_k127_1722374_56 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 305.0
TLS3_k127_1722374_57 methyltransferase K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 300.0
TLS3_k127_1722374_58 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 293.0
TLS3_k127_1722374_59 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002133 269.0
TLS3_k127_1722374_6 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 8.868e-243 779.0
TLS3_k127_1722374_60 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004001 277.0
TLS3_k127_1722374_61 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000832 270.0
TLS3_k127_1722374_62 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000004192 278.0
TLS3_k127_1722374_63 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000003283 263.0
TLS3_k127_1722374_64 Bacterial regulatory proteins, tetR family K22107 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001468 251.0
TLS3_k127_1722374_65 Bacterial PH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003902 238.0
TLS3_k127_1722374_66 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000721 234.0
TLS3_k127_1722374_67 FabA-like domain K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000002975 229.0
TLS3_k127_1722374_68 Competence protein ComEA K02237 - - 0.0000000000000000000000000000000000000000000000000000000000000005996 227.0
TLS3_k127_1722374_69 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000007107 224.0
TLS3_k127_1722374_7 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 3.078e-233 727.0
TLS3_k127_1722374_70 phosphoribosyltransferase K07100 - - 0.00000000000000000000000000000000000000000000000000000000001434 214.0
TLS3_k127_1722374_71 - - - - 0.00000000000000000000000000000000000000000000000000000000004491 223.0
TLS3_k127_1722374_72 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000007643 215.0
TLS3_k127_1722374_73 Phenylacetic acid-responsive transcriptional repressor K02616 - - 0.0000000000000000000000000000000000000000000000000000009878 217.0
TLS3_k127_1722374_74 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000004086 191.0
TLS3_k127_1722374_75 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000001096 200.0
TLS3_k127_1722374_76 Belongs to the glutathione peroxidase family K00432 GO:0003674,GO:0003824,GO:0004601,GO:0004602,GO:0005575,GO:0005623,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0042597,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 1.11.1.9 0.0000000000000000000000000000000000000000000000001308 183.0
TLS3_k127_1722374_77 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000003537 174.0
TLS3_k127_1722374_78 Rieske [2Fe-2S] domain K03890 - - 0.0000000000000000000000000000000000000000000003639 178.0
TLS3_k127_1722374_79 iron dependent repressor - - - 0.0000000000000000000000000000000000000000000003734 173.0
TLS3_k127_1722374_8 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 2.118e-227 709.0
TLS3_k127_1722374_80 - - - - 0.0000000000000000000000000000000000000000000003952 169.0
TLS3_k127_1722374_81 Binding-protein-dependent transport system inner membrane component K05846 - - 0.000000000000000000000000000000000000000000008766 183.0
TLS3_k127_1722374_83 Cytochrome C oxidase subunit II, periplasmic domain K02275 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.0000000000000000000000000000000000000000000495 175.0
TLS3_k127_1722374_84 cytochrome C K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000113 173.0
TLS3_k127_1722374_86 TIR domain - - - 0.00000000000000000000000000000000005785 149.0
TLS3_k127_1722374_87 belongs to the sigma-70 factor family, ECF subfamily - - - 0.000000000000000000000000000000000435 144.0
TLS3_k127_1722374_88 Substrate binding domain of ABC-type glycine betaine transport system K05845 - - 0.0000000000000000000000000000000004584 145.0
TLS3_k127_1722374_89 ABC transporter (Permease) K05846 - - 0.00000000000000000000000000000000269 145.0
TLS3_k127_1722374_9 Polysaccharide biosynthesis C-terminal domain K03980 - - 1.492e-221 701.0
TLS3_k127_1722374_90 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000001177 132.0
TLS3_k127_1722374_91 Heme copper-type cytochrome quinol oxidase subunit 3 K02276,K02299 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 0.00000000000000000000000000000007053 134.0
TLS3_k127_1722374_92 - - - - 0.000000000000000000000000000001856 134.0
TLS3_k127_1722374_93 - - - - 0.000000000000000000000000000005473 121.0
TLS3_k127_1722374_95 transcriptional regulator - - - 0.0000000000000000000000000002256 121.0
TLS3_k127_1722374_96 - - - - 0.000000000000000000000002814 120.0
TLS3_k127_1722374_97 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000004784 92.0
TLS3_k127_1722374_98 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.000000000000002171 87.0
TLS3_k127_1722374_99 - - - - 0.0000000000006211 80.0
TLS3_k127_1737331_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 1.184e-320 989.0
TLS3_k127_1737331_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 6.246e-219 704.0
TLS3_k127_1737331_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 3.548e-211 668.0
TLS3_k127_1737331_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 2.664e-199 631.0
TLS3_k127_1737331_4 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007658 437.0
TLS3_k127_1737331_5 Guanylate kinase homologues. K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005987 275.0
TLS3_k127_1737331_6 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.00000000000000000000000000000000000000008929 152.0
TLS3_k127_1737331_7 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000000009088 135.0
TLS3_k127_1748560_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.03e-257 802.0
TLS3_k127_1748560_1 ABC-type Fe3 transport system permease component K02011,K02063 - - 1.24e-218 690.0
TLS3_k127_1748560_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 488.0
TLS3_k127_1748560_3 endonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 452.0
TLS3_k127_1748560_4 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 418.0
TLS3_k127_1748560_5 ABC transporter, periplasmic binding protein, thiB subfamily K02064 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 430.0
TLS3_k127_1748560_6 Belongs to the ABC transporter superfamily K02052,K02062 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005726 266.0
TLS3_k127_1748560_7 THIamine pyrophosphokinase K00949 - 2.7.6.2 0.000000000000000000000000000000000000000000000000000000000000000001305 236.0
TLS3_k127_1748560_8 endonuclease activity - - - 0.0000000000000001237 85.0
TLS3_k127_1761252_0 Haemolysin-type calcium-binding repeat (2 copies) - - - 5.175e-199 679.0
TLS3_k127_1761252_1 HAD-superfamily subfamily IB hydrolase, TIGR01490 K15781 - 2.3.1.51,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 586.0
TLS3_k127_1761252_10 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 312.0
TLS3_k127_1761252_11 endonuclease activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 316.0
TLS3_k127_1761252_12 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001566 265.0
TLS3_k127_1761252_13 Fe-S protein K07140 - - 0.0000000000000000000000000000000000000000000000000000000000000000001438 242.0
TLS3_k127_1761252_14 - - - - 0.0000000000000000000000000000000000000003928 155.0
TLS3_k127_1761252_15 Domain of unknown function (DUF222) - - - 0.00000000000000000000000000000000007235 142.0
TLS3_k127_1761252_16 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000001651 137.0
TLS3_k127_1761252_17 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000001952 107.0
TLS3_k127_1761252_19 Protein of unknown function (DUF2630) - - - 0.000000000000000000176 95.0
TLS3_k127_1761252_2 diacylglycerol O-acyltransferase K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 580.0
TLS3_k127_1761252_20 COG2335 Secreted and surface protein containing fasciclin-like repeats K19519 - - 0.000000000003006 80.0
TLS3_k127_1761252_21 Domain of unknown function (DUF4328) - - - 0.0000000002654 71.0
TLS3_k127_1761252_23 COG2335 Secreted and surface protein containing fasciclin-like repeats K19519 - - 0.000001486 59.0
TLS3_k127_1761252_24 Host cell surface-exposed lipoprotein - - - 0.0005025 51.0
TLS3_k127_1761252_3 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 560.0
TLS3_k127_1761252_4 Modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009105 539.0
TLS3_k127_1761252_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 503.0
TLS3_k127_1761252_6 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 499.0
TLS3_k127_1761252_7 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 467.0
TLS3_k127_1761252_8 Zinc-binding dehydrogenase K19745 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 454.0
TLS3_k127_1761252_9 Zn-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 415.0
TLS3_k127_1807662_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1726.0
TLS3_k127_1807662_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0 1072.0
TLS3_k127_1807662_2 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 381.0
TLS3_k127_1807662_3 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 372.0
TLS3_k127_1807662_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 366.0
TLS3_k127_1807662_6 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000003631 173.0
TLS3_k127_1816105_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 312.0
TLS3_k127_1816105_1 Pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003617 282.0
TLS3_k127_1816105_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001614 273.0
TLS3_k127_1816105_3 N-terminal domain of galactosyltransferase - - - 0.000000000000000000000000000000000000000000000000008283 201.0
TLS3_k127_1816105_4 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase - - - 0.0000000000000000000000000000000000000000000000004365 188.0
TLS3_k127_1816105_5 Protein conserved in bacteria K20444 - - 0.0000000000001054 84.0
TLS3_k127_1816105_6 4Fe-4S binding domain - - - 0.00000000007142 71.0
TLS3_k127_182537_0 Vitamin B12 dependent methionine synthase activation K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1686.0
TLS3_k127_182537_1 protein synonym multiple resistance and pH homeostasis protein A K00341,K05565 - 1.6.5.3 0.0 1229.0
TLS3_k127_182537_10 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 407.0
TLS3_k127_182537_11 Phosphorylase superfamily K00757,K03784 - 2.4.2.1,2.4.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 377.0
TLS3_k127_182537_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 350.0
TLS3_k127_182537_13 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 350.0
TLS3_k127_182537_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 342.0
TLS3_k127_182537_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 316.0
TLS3_k127_182537_17 Major intrinsic protein K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001016 246.0
TLS3_k127_182537_18 Protein of unknown function (DUF520) K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006172 254.0
TLS3_k127_182537_19 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000001342 245.0
TLS3_k127_182537_2 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.0 1154.0
TLS3_k127_182537_21 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003133 243.0
TLS3_k127_182537_22 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000000367 224.0
TLS3_k127_182537_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000001462 210.0
TLS3_k127_182537_24 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors K12675 - 1.14.11.21 0.0000000000000000000000000000000000000000000000000799 190.0
TLS3_k127_182537_25 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit S4 paralog K04762 - - 0.000000000000000000000000000000000000000000000005649 174.0
TLS3_k127_182537_26 DinB superfamily - - - 0.0000000000000000000000000000000000000000000003149 177.0
TLS3_k127_182537_27 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000004059 165.0
TLS3_k127_182537_28 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000002453 176.0
TLS3_k127_182537_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000000001217 154.0
TLS3_k127_182537_3 Protein synonym NADH dehydrogenase I subunit M K00342 - 1.6.5.3 2.697e-285 882.0
TLS3_k127_182537_30 Transcriptional regulator, rpir family - - - 0.00000000000000000000000206 114.0
TLS3_k127_182537_31 Cytidine and deoxycytidylate deaminase zinc-binding region K11991 - 3.5.4.33 0.00000000000000000000001108 110.0
TLS3_k127_182537_32 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000002196 86.0
TLS3_k127_182537_33 - - - - 0.000008642 52.0
TLS3_k127_182537_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 2.754e-245 772.0
TLS3_k127_182537_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 5.132e-232 729.0
TLS3_k127_182537_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 565.0
TLS3_k127_182537_7 acr, cog1565 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 466.0
TLS3_k127_182537_8 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 432.0
TLS3_k127_182537_9 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 412.0
TLS3_k127_1826696_0 protein synonym multiple resistance and pH homeostasis protein A K00341,K05565,K14086 - 1.6.5.3 2.46e-276 881.0
TLS3_k127_1826696_1 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 2.838e-198 629.0
TLS3_k127_1826696_10 Multisubunit Na H antiporter MnhC subunit K05567 - - 0.000000000000000000000000000000000000397 153.0
TLS3_k127_1826696_11 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000002357 126.0
TLS3_k127_1826696_12 multisubunit Na H antiporter MnhE subunit K05569 - - 0.00000000000000000000000004976 124.0
TLS3_k127_1826696_13 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000001322 96.0
TLS3_k127_1826696_14 monovalent cation:proton antiporter activity K05571 - - 0.00000000000004552 81.0
TLS3_k127_1826696_15 Multisubunit Na H antiporter, MnhF subunit K05563 - - 0.0000003559 55.0
TLS3_k127_1826696_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 503.0
TLS3_k127_1826696_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 377.0
TLS3_k127_1826696_4 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 315.0
TLS3_k127_1826696_5 Diacylglycerol kinase K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001001 288.0
TLS3_k127_1826696_6 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001858 280.0
TLS3_k127_1826696_7 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000000000009938 185.0
TLS3_k127_1826696_8 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000000000000003053 166.0
TLS3_k127_1826696_9 Domain of Unknown Function (DUF1206) - - - 0.00000000000000000000000000000000000000005491 165.0
TLS3_k127_182939_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 2.436e-311 960.0
TLS3_k127_182939_1 Zinc-binding dehydrogenase K17829 - 1.3.1.86 7.383e-262 809.0
TLS3_k127_182939_10 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 492.0
TLS3_k127_182939_11 Polyprenyl synthetase K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 480.0
TLS3_k127_182939_12 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 474.0
TLS3_k127_182939_13 Calcineurin-like phosphoesterase K03651 - 3.1.4.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 464.0
TLS3_k127_182939_14 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 370.0
TLS3_k127_182939_15 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 353.0
TLS3_k127_182939_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 294.0
TLS3_k127_182939_17 IA, variant 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002515 256.0
TLS3_k127_182939_18 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008491 242.0
TLS3_k127_182939_19 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000003018 201.0
TLS3_k127_182939_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 8.516e-221 704.0
TLS3_k127_182939_20 BioY family K03523 - - 0.000000000000000000000000000000000000000000000466 177.0
TLS3_k127_182939_21 RDD family - - - 0.0000000000000000000000000000000000005003 154.0
TLS3_k127_182939_22 RDD family - - - 0.0000000000000000000000000000000007387 140.0
TLS3_k127_182939_24 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000005936 94.0
TLS3_k127_182939_3 Thiolase, C-terminal domain K00626 - 2.3.1.9 8.254e-209 653.0
TLS3_k127_182939_4 KaiC K04485 - - 2.963e-196 621.0
TLS3_k127_182939_5 response to copper ion K07156,K07245,K14166 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 580.0
TLS3_k127_182939_6 dna ligase - GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 559.0
TLS3_k127_182939_7 DisA bacterial checkpoint controller linker region K07067 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 543.0
TLS3_k127_182939_8 Glycosyl hydrolases family 18 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 503.0
TLS3_k127_182939_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 499.0
TLS3_k127_1837024_0 Peptidoglycan-binding domain 1 protein K07260,K21449 - 3.4.17.14 9.463e-295 949.0
TLS3_k127_1837024_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 570.0
TLS3_k127_1837024_2 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 565.0
TLS3_k127_1837024_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 465.0
TLS3_k127_1837024_4 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 418.0
TLS3_k127_1837024_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000001337 237.0
TLS3_k127_1837024_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000009725 209.0
TLS3_k127_1837024_7 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000004347 164.0
TLS3_k127_1837024_8 lipolytic protein G-D-S-L family - - - 0.0000000000181 74.0
TLS3_k127_184287_0 Activator of Hsp90 ATPase 1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001649 244.0
TLS3_k127_184287_1 regulatory protein, arsR - - - 0.0000000000000000000000000000000000000000000000008104 177.0
TLS3_k127_184287_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000006754 163.0
TLS3_k127_184287_3 glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.000000000000000000000000000000000004262 142.0
TLS3_k127_186972_0 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 601.0
TLS3_k127_186972_1 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 299.0
TLS3_k127_186972_2 PFAM Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002251 274.0
TLS3_k127_186972_3 DnaJ molecular chaperone homology domain K03686 - - 0.000000000000000000000000000000000000000000000000000000000005983 213.0
TLS3_k127_186972_4 translation release factor activity K02835,K15034 - - 0.000000000000000000000000000000000000000002082 167.0
TLS3_k127_1889759_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 2.673e-267 832.0
TLS3_k127_1889759_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 486.0
TLS3_k127_1897401_0 Circularly permuted ATP-grasp type 2 - - - 1.572e-241 758.0
TLS3_k127_1897401_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 536.0
TLS3_k127_1897401_2 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005656 292.0
TLS3_k127_1897401_3 Transglutaminase/protease-like homologues - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000005104 233.0
TLS3_k127_1902966_0 Aminotransferase class I and II - - - 1.062e-216 677.0
TLS3_k127_1902966_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 516.0
TLS3_k127_1902966_10 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 323.0
TLS3_k127_1902966_11 Cobinamide kinase / cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000000000000006279 203.0
TLS3_k127_1902966_12 Low temperature requirement - - - 0.0000000000000000000000000000000000000000000303 177.0
TLS3_k127_1902966_2 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 463.0
TLS3_k127_1902966_3 Class II aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 412.0
TLS3_k127_1902966_4 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 404.0
TLS3_k127_1902966_5 membrane K08974 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008515 401.0
TLS3_k127_1902966_6 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 402.0
TLS3_k127_1902966_7 endonuclease activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 375.0
TLS3_k127_1902966_8 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 365.0
TLS3_k127_1902966_9 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 333.0
TLS3_k127_1916478_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 460.0
TLS3_k127_1916478_1 ABC transporter K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 289.0
TLS3_k127_1916478_2 Protein of unknown function (DUF2786) - - - 0.00000000000000000000000000000000000000000000000000000000002063 214.0
TLS3_k127_1916478_4 transcriptional regulator - - - 0.00000000000000000000000007993 119.0
TLS3_k127_1916478_5 COG2801 Transposase and inactivated derivatives - - - 0.000000214 55.0
TLS3_k127_1933569_0 DNA Topoisomerase IV K02469 - 5.99.1.3 0.0 1334.0
TLS3_k127_1933569_1 TopoisomeraseII K02470 - 5.99.1.3 0.0 1113.0
TLS3_k127_1933569_10 DNA polymerase III beta subunit K02338 - 2.7.7.7 6.481e-198 620.0
TLS3_k127_1933569_11 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 610.0
TLS3_k127_1933569_12 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 596.0
TLS3_k127_1933569_13 Cysteine desulfurase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 597.0
TLS3_k127_1933569_14 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 546.0
TLS3_k127_1933569_15 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009594 538.0
TLS3_k127_1933569_16 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 533.0
TLS3_k127_1933569_17 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 504.0
TLS3_k127_1933569_18 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 510.0
TLS3_k127_1933569_19 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 482.0
TLS3_k127_1933569_2 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0 1041.0
TLS3_k127_1933569_20 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 487.0
TLS3_k127_1933569_21 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 472.0
TLS3_k127_1933569_22 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 446.0
TLS3_k127_1933569_23 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 449.0
TLS3_k127_1933569_24 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 460.0
TLS3_k127_1933569_25 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 423.0
TLS3_k127_1933569_26 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 430.0
TLS3_k127_1933569_27 60Kd inner membrane protein K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 425.0
TLS3_k127_1933569_28 FAD-linked oxidoreductase K00103 - 1.1.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 413.0
TLS3_k127_1933569_29 belongs to the sigma-70 factor family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 403.0
TLS3_k127_1933569_3 Putative diguanylate phosphodiesterase - - - 1.122e-270 854.0
TLS3_k127_1933569_30 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 373.0
TLS3_k127_1933569_32 polyphosphate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 363.0
TLS3_k127_1933569_33 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 353.0
TLS3_k127_1933569_34 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 336.0
TLS3_k127_1933569_35 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 321.0
TLS3_k127_1933569_36 Saccharopine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 337.0
TLS3_k127_1933569_37 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 320.0
TLS3_k127_1933569_38 Putative peptidoglycan binding domain K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 317.0
TLS3_k127_1933569_39 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 305.0
TLS3_k127_1933569_4 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 1.123e-250 779.0
TLS3_k127_1933569_40 Putative single-stranded nucleic acids-binding domain K06346 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009457 306.0
TLS3_k127_1933569_41 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 293.0
TLS3_k127_1933569_42 o-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 290.0
TLS3_k127_1933569_43 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 297.0
TLS3_k127_1933569_44 -acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 284.0
TLS3_k127_1933569_45 Arsenical pump membrane protein K03893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001469 291.0
TLS3_k127_1933569_46 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003188 269.0
TLS3_k127_1933569_47 Nudix hydrolase K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000001796 255.0
TLS3_k127_1933569_48 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002428 257.0
TLS3_k127_1933569_49 ParB-like nuclease domain K03497 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000007288 254.0
TLS3_k127_1933569_5 Protein synonym acyl-CoA synthetase K15868 - 6.2.1.7 1.045e-243 760.0
TLS3_k127_1933569_50 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003475 245.0
TLS3_k127_1933569_51 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000002621 240.0
TLS3_k127_1933569_52 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000006141 232.0
TLS3_k127_1933569_53 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000001088 229.0
TLS3_k127_1933569_54 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000000000000000000000001741 254.0
TLS3_k127_1933569_55 Family of unknown function (DUF5318) - - - 0.00000000000000000000000000000000000000000000000000000000000000001794 226.0
TLS3_k127_1933569_56 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000006944 226.0
TLS3_k127_1933569_57 Mazg nucleotide pyrophosphohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000001448 226.0
TLS3_k127_1933569_58 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000000002251 199.0
TLS3_k127_1933569_59 Binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000005765 186.0
TLS3_k127_1933569_6 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 2.15e-225 711.0
TLS3_k127_1933569_60 deazaflavin-dependent nitroreductase family protein - - - 0.0000000000000000000000000000000000000000000000002169 185.0
TLS3_k127_1933569_61 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000000000003864 178.0
TLS3_k127_1933569_62 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000008193 179.0
TLS3_k127_1933569_63 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000000000000000004724 170.0
TLS3_k127_1933569_64 PFAM Acetyltransferase (GNAT) family K03395 - 2.3.1.60 0.0000000000000000000000000000000000000007635 153.0
TLS3_k127_1933569_65 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0015037,GO:0015038,GO:0016020,GO:0016209,GO:0016491,GO:0016651,GO:0016657,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0022900,GO:0030312,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0080007,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000000001378 151.0
TLS3_k127_1933569_66 - - - - 0.00000000000000000000000000000000000002384 149.0
TLS3_k127_1933569_67 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000716 157.0
TLS3_k127_1933569_68 Ribosomal RNA small subunit methyltransferase G K03501 - 2.1.1.170 0.000000000000000000000000000000000006306 147.0
TLS3_k127_1933569_69 acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000001416 148.0
TLS3_k127_1933569_7 Protein kinase domain K08884,K12132 - 2.7.11.1 4e-220 698.0
TLS3_k127_1933569_71 - - - - 0.000000000000000000000000000000001058 144.0
TLS3_k127_1933569_72 YCII-related domain - - - 0.000000000000000000000000000000001079 137.0
TLS3_k127_1933569_73 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.000000000000000000000000000000005649 135.0
TLS3_k127_1933569_74 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000000001871 131.0
TLS3_k127_1933569_75 AntiSigma factor - - - 0.000000000000000000000000000006127 131.0
TLS3_k127_1933569_76 Putative stress-induced transcription regulator - - - 0.000000000000000000000000001837 125.0
TLS3_k127_1933569_77 Bacterial PH domain - - - 0.00000000000000000000001231 108.0
TLS3_k127_1933569_8 acyl-CoA dehydrogenase - - - 2.974e-210 659.0
TLS3_k127_1933569_80 Ribosomal protein L34 K02914 - - 0.0000000000008957 71.0
TLS3_k127_1933569_83 Colicin V production protein - - - 0.000000009622 67.0
TLS3_k127_1933569_84 Lytic murein transglycosylase K00786,K08305 - - 0.000001003 61.0
TLS3_k127_1933569_85 FR47-like protein K03789 - 2.3.1.128 0.00002968 57.0
TLS3_k127_1933569_9 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382,K17883 - 1.8.1.15,1.8.1.4 9.124e-203 642.0
TLS3_k127_1942758_0 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0 1173.0
TLS3_k127_1942758_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676,K01678,K03780 - 4.2.1.2,4.2.1.32 5.033e-308 949.0
TLS3_k127_1942758_11 Psort location Cytoplasmic, score - - - 0.0000000000000001472 91.0
TLS3_k127_1942758_12 Carbon-nitrogen hydrolase K01431 - 3.5.1.6 0.00000009516 54.0
TLS3_k127_1942758_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 3.855e-280 867.0
TLS3_k127_1942758_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 470.0
TLS3_k127_1942758_4 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 471.0
TLS3_k127_1942758_5 Initiation factor 2 subunit family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 388.0
TLS3_k127_1942758_6 Platelet-activating factor acetylhydrolase, isoform II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 377.0
TLS3_k127_1942758_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001751 267.0
TLS3_k127_1942758_8 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000002145 231.0
TLS3_k127_1942758_9 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000009177 153.0
TLS3_k127_1948900_0 Cell division protein FtsA K03569 - - 3.148e-202 631.0
TLS3_k127_1948900_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 569.0
TLS3_k127_1948900_2 Glutathione S-transferase K07393 - 1.8.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 494.0
TLS3_k127_1948900_3 Thioesterase-like superfamily K10805 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 477.0
TLS3_k127_1948900_4 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 436.0
TLS3_k127_1948900_5 RIO1 family K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000004135 201.0
TLS3_k127_1948900_6 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000005491 194.0
TLS3_k127_1987672_0 AMP-binding enzyme C-terminal domain K00666 - - 1.816e-277 861.0
TLS3_k127_1987672_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 569.0
TLS3_k127_1987672_10 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000001749 258.0
TLS3_k127_1987672_11 PFAM regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000001954 157.0
TLS3_k127_1987672_13 Belongs to the CinA family - - - 0.000000000000000003696 91.0
TLS3_k127_1987672_2 Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 519.0
TLS3_k127_1987672_3 beta-1,4-mannooligosaccharide phosphorylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 491.0
TLS3_k127_1987672_4 extracellular matrix structural constituent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 490.0
TLS3_k127_1987672_5 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006005 395.0
TLS3_k127_1987672_6 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 376.0
TLS3_k127_1987672_7 Belongs to the carbohydrate kinase PfkB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 353.0
TLS3_k127_1987672_8 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001508 288.0
TLS3_k127_1987672_9 Putative zinc-binding metallo-peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001323 276.0
TLS3_k127_2000064_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.899e-278 859.0
TLS3_k127_2000064_1 Protein of unknown function (DUF933) K06942 - - 2.614e-203 636.0
TLS3_k127_2000064_10 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 338.0
TLS3_k127_2000064_11 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 334.0
TLS3_k127_2000064_12 Protein conserved in bacteria K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 336.0
TLS3_k127_2000064_13 translation initiation factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001905 273.0
TLS3_k127_2000064_14 Domain of unknown function (DUF4157) - - - 0.000000000000000000000000000000000000000000000000000000001061 223.0
TLS3_k127_2000064_15 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000000002757 178.0
TLS3_k127_2000064_17 domain protein - - - 0.00000000000003273 82.0
TLS3_k127_2000064_18 - - - - 0.00000000000003412 85.0
TLS3_k127_2000064_19 Protein conserved in bacteria - - - 0.000000000004354 78.0
TLS3_k127_2000064_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 598.0
TLS3_k127_2000064_3 PHP domain K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 587.0
TLS3_k127_2000064_4 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 588.0
TLS3_k127_2000064_5 Membrane bound O-acyl transferase MBOAT family protein K03739,K19294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 406.0
TLS3_k127_2000064_6 Tetrapyrrole (Corrin/Porphyrin) Methylases K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009823 379.0
TLS3_k127_2000064_7 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 383.0
TLS3_k127_2000064_8 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 373.0
TLS3_k127_2000064_9 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 350.0
TLS3_k127_2002524_0 PFAM alpha amylase, catalytic K01182 - 3.2.1.10 1.059e-245 771.0
TLS3_k127_2002524_1 Pyridoxal-phosphate dependent enzyme K01505,K05396 - 3.5.99.7,4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 529.0
TLS3_k127_2002524_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002872 275.0
TLS3_k127_2031484_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0 1122.0
TLS3_k127_2031484_1 Seryl-tRNA synthetase N-terminal domain K01875 - 6.1.1.11 2.022e-209 659.0
TLS3_k127_2031484_10 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000000000006891 99.0
TLS3_k127_2031484_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 599.0
TLS3_k127_2031484_3 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02298 - 1.10.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007393 591.0
TLS3_k127_2031484_4 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02862 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 425.0
TLS3_k127_2031484_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 377.0
TLS3_k127_2031484_6 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 338.0
TLS3_k127_2031484_7 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0010181,GO:0016491,GO:0016614,GO:0016899,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032553,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042803,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 304.0
TLS3_k127_2031484_8 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000009619 244.0
TLS3_k127_2031484_9 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000003565 180.0
TLS3_k127_203265_0 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2587.0
TLS3_k127_203265_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1082.0
TLS3_k127_203265_10 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 9.234e-216 681.0
TLS3_k127_203265_11 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 2.577e-212 685.0
TLS3_k127_203265_12 FMN-dependent dehydrogenase K00101 - 1.1.2.3 7.119e-197 627.0
TLS3_k127_203265_13 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 2.014e-195 632.0
TLS3_k127_203265_14 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 602.0
TLS3_k127_203265_15 synthase III K00648,K22317 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 576.0
TLS3_k127_203265_16 chorismate binding enzyme K02552 - 5.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 528.0
TLS3_k127_203265_17 AAA domain K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000672 509.0
TLS3_k127_203265_18 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 508.0
TLS3_k127_203265_19 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 456.0
TLS3_k127_203265_2 synthetase K22319 - 6.1.3.1 6.57e-320 1017.0
TLS3_k127_203265_20 ATPase family associated with various cellular activities (AAA) K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 460.0
TLS3_k127_203265_21 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 430.0
TLS3_k127_203265_22 3-beta hydroxysteroid dehydrogenase isomerase K16045,K22320 GO:0000166,GO:0003674,GO:0003824,GO:0003854,GO:0004769,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016020,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016853,GO:0016860,GO:0016863,GO:0030283,GO:0033764,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901360,GO:1901363 1.1.1.145,1.1.1.412,5.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 424.0
TLS3_k127_203265_23 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 416.0
TLS3_k127_203265_24 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 401.0
TLS3_k127_203265_25 peptidase S58, DmpA K18572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 398.0
TLS3_k127_203265_26 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 387.0
TLS3_k127_203265_27 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 381.0
TLS3_k127_203265_28 COG3588 Fructose-1,6-bisphosphate aldolase K01623 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 386.0
TLS3_k127_203265_29 polyphosphate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 381.0
TLS3_k127_203265_3 helicase K03722 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.4.12 6.047e-314 972.0
TLS3_k127_203265_30 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 379.0
TLS3_k127_203265_31 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 379.0
TLS3_k127_203265_32 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 388.0
TLS3_k127_203265_33 UTRA K03710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 374.0
TLS3_k127_203265_34 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 364.0
TLS3_k127_203265_35 PFAM Metallo-beta-lactamase superfamily - GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 354.0
TLS3_k127_203265_36 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007114 376.0
TLS3_k127_203265_37 Acetyltransferase (isoleucine patch K00661 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 2.3.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 345.0
TLS3_k127_203265_38 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 330.0
TLS3_k127_203265_39 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 325.0
TLS3_k127_203265_4 AMP-dependent synthetase and ligase - - - 3.98e-290 900.0
TLS3_k127_203265_40 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 306.0
TLS3_k127_203265_41 low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 296.0
TLS3_k127_203265_42 hydrolase activity, acting on ester bonds K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 317.0
TLS3_k127_203265_43 formamidopyrimidine-DNA glycosylase K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 289.0
TLS3_k127_203265_44 transferase activity, transferring alkyl or aryl (other than methyl) groups K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001087 277.0
TLS3_k127_203265_45 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) K08680 - 4.2.99.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000004132 276.0
TLS3_k127_203265_46 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004734 282.0
TLS3_k127_203265_47 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007317 252.0
TLS3_k127_203265_48 Dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001001 266.0
TLS3_k127_203265_49 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000001679 250.0
TLS3_k127_203265_5 AMP-binding enzyme C-terminal domain K00666 - - 6.236e-271 858.0
TLS3_k127_203265_51 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000007015 209.0
TLS3_k127_203265_52 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000000000000007809 204.0
TLS3_k127_203265_53 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000007875 201.0
TLS3_k127_203265_54 Endo-1,4-beta-xylanase - - - 0.0000000000000000000000000000000000000000000000227 188.0
TLS3_k127_203265_55 LysM domain - - - 0.00000000000000000000000000000000000000000002084 171.0
TLS3_k127_203265_56 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000000000000000000000000000000000001042 151.0
TLS3_k127_203265_58 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000127 102.0
TLS3_k127_203265_59 - - - - 0.00000000000000000003039 93.0
TLS3_k127_203265_6 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 2.098e-269 831.0
TLS3_k127_203265_60 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.0000000000000001027 87.0
TLS3_k127_203265_62 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000001329 83.0
TLS3_k127_203265_63 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000009878 64.0
TLS3_k127_203265_64 CAAX protease self-immunity K07052 - - 0.0000001138 64.0
TLS3_k127_203265_65 Putative adhesin - - - 0.00000726 56.0
TLS3_k127_203265_66 Tetratricopeptide repeats - - - 0.00005225 54.0
TLS3_k127_203265_67 Protein of unknown function (DUF2510) - - - 0.00006023 55.0
TLS3_k127_203265_68 membrane protein TerC - - - 0.0002799 46.0
TLS3_k127_203265_7 ABC transporter transmembrane region K06147 - - 1.614e-239 769.0
TLS3_k127_203265_8 ABC transporter transmembrane region K06147 - - 1.402e-235 743.0
TLS3_k127_203265_9 glutamate synthase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 2.69e-226 710.0
TLS3_k127_2045072_0 Domain of unknown function (DUF4142) - - - 0.00000000000000000000000000000000000004089 161.0
TLS3_k127_2045072_1 PFAM Uncharacterised BCR, COG1937 K21600 - - 0.00000000000000000000000000000002584 128.0
TLS3_k127_2045072_2 CopC domain K07156,K14166 - - 0.0000000000000000000000000000165 136.0
TLS3_k127_2045072_3 Penicillinase repressor - - - 0.0000000000000000000005504 106.0
TLS3_k127_2058981_0 Catalyzes the synthesis of activated sulfate K00955 - 2.7.1.25,2.7.7.4 0.0 1061.0
TLS3_k127_2058981_1 - - - - 1.437e-282 888.0
TLS3_k127_2058981_10 transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000000000000001007 202.0
TLS3_k127_2058981_11 Pfam:DUF385 - - - 0.00000000000000000000000000000000000000000000000003691 192.0
TLS3_k127_2058981_12 - - - - 0.000000000000000000000000000000002512 135.0
TLS3_k127_2058981_13 Domain of unknown function (DUF222) - - - 0.000000000000000000000000000000002642 138.0
TLS3_k127_2058981_14 Belongs to the ompA family - - - 0.000000000001018 79.0
TLS3_k127_2058981_2 Sulfatase - - - 8.802e-255 797.0
TLS3_k127_2058981_3 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 1.353e-220 693.0
TLS3_k127_2058981_4 sulfate adenylyltransferase K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000677 550.0
TLS3_k127_2058981_5 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 430.0
TLS3_k127_2058981_6 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 388.0
TLS3_k127_2058981_7 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 344.0
TLS3_k127_2058981_8 taurine dioxygenase K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000003638 247.0
TLS3_k127_2058981_9 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000003407 230.0
TLS3_k127_2147309_0 MMPL family K06994 - - 2.299e-239 763.0
TLS3_k127_2147309_1 ACT domain K00928 - 2.7.2.4 5.412e-227 707.0
TLS3_k127_2147309_10 Antibiotic biosynthesis monooxygenase K21481 - 1.14.99.57 0.00000000000000000000000000000000000000000000000396 175.0
TLS3_k127_2147309_11 Phosphoribosyl-ATP pyrophosphohydrolase - - - 0.00000000000000000000000000000000000000000001695 163.0
TLS3_k127_2147309_12 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000006221 139.0
TLS3_k127_2147309_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 529.0
TLS3_k127_2147309_3 ATP-dependent DNA helicase activity K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 481.0
TLS3_k127_2147309_4 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 436.0
TLS3_k127_2147309_5 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 417.0
TLS3_k127_2147309_6 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009715 404.0
TLS3_k127_2147309_7 Helix-turn-helix domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 353.0
TLS3_k127_2147309_8 histidine kinase HAMP region domain protein K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000006374 267.0
TLS3_k127_2147309_9 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003435 263.0
TLS3_k127_2194846_0 Transglutaminase/protease-like homologues - - - 1.864e-243 792.0
TLS3_k127_2194846_1 Belongs to the glycosyl hydrolase 13 family K01214,K02438 - 3.2.1.196,3.2.1.68 7.634e-240 762.0
TLS3_k127_2194846_10 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 403.0
TLS3_k127_2194846_11 Enoyl-CoA hydratase/isomerase K01692,K13766 - 4.2.1.17,4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006401 409.0
TLS3_k127_2194846_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 371.0
TLS3_k127_2194846_13 Phytanoyl-CoA dioxygenase (PhyH) K00477,K18565 - 1.14.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 365.0
TLS3_k127_2194846_14 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 371.0
TLS3_k127_2194846_15 Protein of unknown function (DUF459) K09795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 365.0
TLS3_k127_2194846_16 basic membrane K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 362.0
TLS3_k127_2194846_17 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 342.0
TLS3_k127_2194846_18 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 361.0
TLS3_k127_2194846_19 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 337.0
TLS3_k127_2194846_2 ABC transporter K02056 - 3.6.3.17 2.157e-197 629.0
TLS3_k127_2194846_20 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 317.0
TLS3_k127_2194846_21 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 313.0
TLS3_k127_2194846_22 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007169 292.0
TLS3_k127_2194846_23 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001847 268.0
TLS3_k127_2194846_24 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005422 271.0
TLS3_k127_2194846_25 cysteine-type peptidase activity K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000000442 236.0
TLS3_k127_2194846_26 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000103 211.0
TLS3_k127_2194846_27 Protein of unknown function (DUF501) K09009 - - 0.000000000000000000000000000000000000000000000000826 192.0
TLS3_k127_2194846_28 XdhC and CoxI family - - - 0.000000000000000000000000000000000000000000000001818 175.0
TLS3_k127_2194846_29 Ppx GppA phosphatase - - - 0.0000000000000000000000000000000000000000002012 176.0
TLS3_k127_2194846_3 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 578.0
TLS3_k127_2194846_31 lysyltransferase activity K07027,K20468 - - 0.000000000000000000000000000000227 139.0
TLS3_k127_2194846_32 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.00000000000000000000001818 112.0
TLS3_k127_2194846_33 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000002643 90.0
TLS3_k127_2194846_34 PaaX-like protein K02616 - - 0.00003666 47.0
TLS3_k127_2194846_4 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 583.0
TLS3_k127_2194846_5 von Willebrand factor (vWF) type A domain K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 556.0
TLS3_k127_2194846_6 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 501.0
TLS3_k127_2194846_7 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 500.0
TLS3_k127_2194846_8 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 453.0
TLS3_k127_2194846_9 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 452.0
TLS3_k127_2210402_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472,K13015 - 1.1.1.136,1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 511.0
TLS3_k127_2210402_1 helicase activity - - - 0.0000000000000000000000000000000000000000000000000000000000009674 214.0
TLS3_k127_2210402_2 Major facilitator superfamily K08151 - - 0.00001587 57.0
TLS3_k127_2210402_3 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00004733 48.0
TLS3_k127_2297469_0 hydrolase, family 65, central catalytic K05342 - 2.4.1.64 0.0 1176.0
TLS3_k127_2297469_1 synthetase K18688 - 6.2.1.42 9.734e-283 876.0
TLS3_k127_2297469_10 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 317.0
TLS3_k127_2297469_11 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005342 267.0
TLS3_k127_2297469_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002561 246.0
TLS3_k127_2297469_13 Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000000000000000000000000005507 220.0
TLS3_k127_2297469_14 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000001322 216.0
TLS3_k127_2297469_15 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000000000000000000005707 207.0
TLS3_k127_2297469_16 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000000000003096 132.0
TLS3_k127_2297469_17 2-phosphosulpholactate phosphatase K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.0000000000000000000000000000001484 132.0
TLS3_k127_2297469_18 Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family K00561 - 2.1.1.184 0.0000000000000000000000000000001956 131.0
TLS3_k127_2297469_19 Nitroreductase family - - - 0.000000000000000000000000000004995 130.0
TLS3_k127_2297469_2 acyl-CoA dehydrogenase activity - - - 1.524e-194 615.0
TLS3_k127_2297469_3 acyl-CoA dehydrogenase K22027 - 1.14.13.235 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 535.0
TLS3_k127_2297469_4 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 485.0
TLS3_k127_2297469_5 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 448.0
TLS3_k127_2297469_6 PD-(D/E)XK nuclease superfamily K07465 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 419.0
TLS3_k127_2297469_7 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008383 385.0
TLS3_k127_2297469_8 short-chain dehydrogenase reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 383.0
TLS3_k127_2297469_9 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 317.0
TLS3_k127_231499_0 AMP-binding enzyme C-terminal domain - - - 3.332e-279 864.0
TLS3_k127_231499_1 Pyridoxal-dependent decarboxylase conserved domain K01580,K01634 - 4.1.1.15,4.1.2.27 2.578e-214 671.0
TLS3_k127_231499_2 Aminotransferase class-III K00596 - 4.1.1.64 6.009e-196 619.0
TLS3_k127_231499_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 574.0
TLS3_k127_231499_4 protein conserved in bacteria K09781 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 330.0
TLS3_k127_231499_5 acyl-CoA hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001514 295.0
TLS3_k127_231499_6 Guanylate cyclase - GO:0000287,GO:0003674,GO:0003824,GO:0004016,GO:0004383,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006182,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0007186,GO:0007187,GO:0007188,GO:0007189,GO:0008074,GO:0008150,GO:0008152,GO:0008179,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0010033,GO:0014070,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019899,GO:0019932,GO:0019933,GO:0019935,GO:0023052,GO:0030145,GO:0030425,GO:0031224,GO:0031226,GO:0031683,GO:0032991,GO:0033993,GO:0034641,GO:0034654,GO:0035556,GO:0035690,GO:0036477,GO:0042221,GO:0042493,GO:0042995,GO:0043005,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044444,GO:0044445,GO:0044459,GO:0044463,GO:0044464,GO:0044877,GO:0045121,GO:0046058,GO:0046068,GO:0046390,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0046982,GO:0046983,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052652,GO:0055086,GO:0061478,GO:0065007,GO:0070887,GO:0071236,GO:0071310,GO:0071396,GO:0071407,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097305,GO:0097306,GO:0097447,GO:0097458,GO:0098589,GO:0098805,GO:0098857,GO:0120025,GO:0120038,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901654,GO:1901655,GO:1901700,GO:1901701,GO:1904321,GO:1904322 - 0.000000000000000000000000000000000000000000000000000000000000003386 242.0
TLS3_k127_231499_7 MscS Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000004927 225.0
TLS3_k127_231499_8 Guanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000003502 207.0
TLS3_k127_231499_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000002569 84.0
TLS3_k127_241507_0 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 395.0
TLS3_k127_241507_1 PFAM bifunctional deaminase-reductase domain protein - - - 0.000000000000000000000000000000000002037 138.0
TLS3_k127_241507_2 F420H(2)-dependent quinone reductase - - - 0.00001992 49.0
TLS3_k127_249017_0 ABC transporter K01995 - - 0.0 1039.0
TLS3_k127_249017_1 penicillin-binding protein - - - 0.0 1011.0
TLS3_k127_249017_2 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 463.0
TLS3_k127_249017_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 330.0
TLS3_k127_249017_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009754 242.0
TLS3_k127_249017_5 alpha-ribazole phosphatase activity K02226,K15634,K22305,K22306,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.3,3.1.3.73,3.1.3.85,5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000006321 241.0
TLS3_k127_249017_6 - K07164,K22391 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000001314 222.0
TLS3_k127_249017_7 endonuclease activity - - - 0.00000000000000000000000000000000000002767 149.0
TLS3_k127_2593132_0 DNA polymerase alpha chain like domain K02337 - 2.7.7.7 0.0 2080.0
TLS3_k127_2593132_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1730.0
TLS3_k127_2593132_10 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 505.0
TLS3_k127_2593132_11 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 498.0
TLS3_k127_2593132_12 acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 488.0
TLS3_k127_2593132_13 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 469.0
TLS3_k127_2593132_14 Bacterial lipid A biosynthesis acyltransferase K22311 - 2.3.1.265 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 458.0
TLS3_k127_2593132_15 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 456.0
TLS3_k127_2593132_16 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 380.0
TLS3_k127_2593132_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 372.0
TLS3_k127_2593132_18 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 377.0
TLS3_k127_2593132_19 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 354.0
TLS3_k127_2593132_2 Putative diguanylate phosphodiesterase - - - 0.0 1057.0
TLS3_k127_2593132_20 Protein of unknown function (DUF3048) C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 347.0
TLS3_k127_2593132_21 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 286.0
TLS3_k127_2593132_22 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 288.0
TLS3_k127_2593132_23 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006387 276.0
TLS3_k127_2593132_24 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006302 274.0
TLS3_k127_2593132_25 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002063 269.0
TLS3_k127_2593132_26 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002263 275.0
TLS3_k127_2593132_27 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001727 261.0
TLS3_k127_2593132_28 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000006141 255.0
TLS3_k127_2593132_29 HIT domain K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000000000000000001287 253.0
TLS3_k127_2593132_3 Protein of unknown function, DUF255 K06888 - - 3.318e-297 931.0
TLS3_k127_2593132_30 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002461 250.0
TLS3_k127_2593132_31 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000000000003191 244.0
TLS3_k127_2593132_32 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000016 260.0
TLS3_k127_2593132_33 Alanine racemase, N-terminal domain K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000008078 228.0
TLS3_k127_2593132_34 regulation of cell shape - - - 0.0000000000000000000000000000000000000000000000000000000000000005029 234.0
TLS3_k127_2593132_36 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000000005909 205.0
TLS3_k127_2593132_37 Protein of unknown function (DUF2587) - - - 0.00000000000000000000000000000000000000000000000101 195.0
TLS3_k127_2593132_38 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 0.00000000000000000000000000000000000000000001569 177.0
TLS3_k127_2593132_4 Threonyl and Alanyl tRNA synthetase second additional domain K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 1.257e-227 722.0
TLS3_k127_2593132_40 Protein of unknown function (DUF2510) - - - 0.00004061 51.0
TLS3_k127_2593132_5 tRNA synthetases class I (C) catalytic domain K15526 - 6.3.1.13 4.262e-207 647.0
TLS3_k127_2593132_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 582.0
TLS3_k127_2593132_7 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 532.0
TLS3_k127_2593132_8 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006904 511.0
TLS3_k127_2593132_9 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 508.0
TLS3_k127_261397_0 Aminotransferase class-V - - - 1.828e-224 709.0
TLS3_k127_261397_1 2-nitropropane dioxygenase - - - 5.994e-203 637.0
TLS3_k127_261397_10 Glyoxalase-like domain K04750 - - 0.00000000000000000000000000000000000000000000001584 186.0
TLS3_k127_261397_11 - - - - 0.000000000000000000000000000009496 120.0
TLS3_k127_261397_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 483.0
TLS3_k127_261397_3 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005646 449.0
TLS3_k127_261397_4 E1-E2 ATPase K12952 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 387.0
TLS3_k127_261397_5 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 372.0
TLS3_k127_261397_6 heme binding K21471,K21472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 334.0
TLS3_k127_261397_7 regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006611 288.0
TLS3_k127_261397_8 Glycosyltransferase family 20 K00697,K16055 GO:0003674,GO:0003824,GO:0003825,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0030312,GO:0033554,GO:0034637,GO:0035251,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046527,GO:0046872,GO:0046914,GO:0047260,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:0071944,GO:1901576 2.4.1.15,2.4.1.347,3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000005492 256.0
TLS3_k127_261397_9 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000000003986 179.0
TLS3_k127_2628140_0 ATPase involved in DNA repair - - - 0.0 2562.0
TLS3_k127_2628140_1 ATP-dependent helicase K03578 - 3.6.4.13 0.0 1639.0
TLS3_k127_2628140_10 Thioesterase-like superfamily K10805 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 404.0
TLS3_k127_2628140_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 392.0
TLS3_k127_2628140_12 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 348.0
TLS3_k127_2628140_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003736 263.0
TLS3_k127_2628140_14 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000219 262.0
TLS3_k127_2628140_15 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000002963 246.0
TLS3_k127_2628140_16 - - - - 0.0000000000000000000000000000000000000000000000006398 182.0
TLS3_k127_2628140_17 DoxX family - - - 0.000000000000000000000000000000000003466 142.0
TLS3_k127_2628140_18 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000001622 128.0
TLS3_k127_2628140_19 sequence-specific DNA binding K15773 - - 0.000000000000000000000004867 105.0
TLS3_k127_2628140_2 peptidyl-serine autophosphorylation - - - 0.0 1150.0
TLS3_k127_2628140_20 - - - - 0.000000000000000000000533 108.0
TLS3_k127_2628140_21 GDSL-like Lipase/Acylhydrolase - - - 0.00000001844 66.0
TLS3_k127_2628140_3 ABC transporter transmembrane region K06147 - - 4.009e-299 941.0
TLS3_k127_2628140_4 - - - - 5.277e-279 909.0
TLS3_k127_2628140_5 Belongs to the long-chain O-acyltransferase family - - - 5.498e-256 801.0
TLS3_k127_2628140_6 ABC transporter transmembrane region K06147 - - 2.888e-253 803.0
TLS3_k127_2628140_7 Amidase K01426 - 3.5.1.4 3.025e-196 622.0
TLS3_k127_2628140_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 567.0
TLS3_k127_2628140_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 444.0
TLS3_k127_2638367_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000269 271.0
TLS3_k127_2638367_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000179 251.0
TLS3_k127_2638367_2 PIN domain K07064 - - 0.00000000000000000000000000000000000000000000000000000000000000003715 224.0
TLS3_k127_2638367_3 positive regulation of growth - - - 0.0000000000000000000000000000000000001776 145.0
TLS3_k127_2652040_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1382.0
TLS3_k127_2652040_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 3.349e-298 923.0
TLS3_k127_2652040_10 Oxidoreductase molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 468.0
TLS3_k127_2652040_11 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 450.0
TLS3_k127_2652040_12 heme binding K06401,K21472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 396.0
TLS3_k127_2652040_13 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 390.0
TLS3_k127_2652040_14 Histidine biosynthesis protein K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 361.0
TLS3_k127_2652040_15 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 394.0
TLS3_k127_2652040_16 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 355.0
TLS3_k127_2652040_17 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 349.0
TLS3_k127_2652040_18 PFAM Oxidoreductase, molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 336.0
TLS3_k127_2652040_19 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 333.0
TLS3_k127_2652040_2 Anthranilate synthase component I, N terminal region K01657 - 4.1.3.27 8.502e-288 892.0
TLS3_k127_2652040_20 LysM domain K01449 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 348.0
TLS3_k127_2652040_21 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 328.0
TLS3_k127_2652040_22 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 327.0
TLS3_k127_2652040_23 DNA alkylation repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 291.0
TLS3_k127_2652040_24 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001199 281.0
TLS3_k127_2652040_25 Aminomethyltransferase folate-binding domain K06980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006416 274.0
TLS3_k127_2652040_26 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005093 269.0
TLS3_k127_2652040_27 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000111 258.0
TLS3_k127_2652040_28 Oxidoreductase FAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008583 247.0
TLS3_k127_2652040_29 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000001575 234.0
TLS3_k127_2652040_3 Oligopeptidase F K08602 - - 5.14e-285 889.0
TLS3_k127_2652040_30 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000002703 217.0
TLS3_k127_2652040_31 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000006587 184.0
TLS3_k127_2652040_32 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000000001746 181.0
TLS3_k127_2652040_33 - K07018 - - 0.00000000000000000000000000000000000000000000000004812 186.0
TLS3_k127_2652040_34 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.0000000000000000000000000000000000000000000000006999 192.0
TLS3_k127_2652040_35 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000005686 172.0
TLS3_k127_2652040_37 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000011 164.0
TLS3_k127_2652040_38 - - - - 0.000000000000000000000000000000000000000000645 162.0
TLS3_k127_2652040_39 Anti-sigma-K factor rskA - - - 0.000000000000000000000000000000000000000001386 166.0
TLS3_k127_2652040_4 cytochrome P450 K20497 - 1.14.15.14 2.482e-205 645.0
TLS3_k127_2652040_41 Transcriptional regulator - - - 0.000000000000000000000000000000000003804 146.0
TLS3_k127_2652040_43 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000003399 119.0
TLS3_k127_2652040_44 Universal stress protein family - - - 0.00000000000000000000000004013 119.0
TLS3_k127_2652040_45 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000002319 109.0
TLS3_k127_2652040_46 Mycobacterial 4 TMS phage holin, superfamily IV - - - 0.00000000000000000003142 99.0
TLS3_k127_2652040_48 Ethyl tert-butyl ether degradation EthD - - - 0.0000000000000000883 85.0
TLS3_k127_2652040_49 Ion channel - - - 0.000000005677 66.0
TLS3_k127_2652040_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 9.57e-197 621.0
TLS3_k127_2652040_50 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0002943 53.0
TLS3_k127_2652040_6 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 567.0
TLS3_k127_2652040_7 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007741 563.0
TLS3_k127_2652040_8 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 543.0
TLS3_k127_2652040_9 Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol K15520 - 2.3.1.189 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 482.0
TLS3_k127_2667039_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 496.0
TLS3_k127_2667039_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 447.0
TLS3_k127_2667039_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 434.0
TLS3_k127_2667039_3 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 377.0
TLS3_k127_2667039_4 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 302.0
TLS3_k127_2667039_5 Replication protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 298.0
TLS3_k127_2667039_6 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18958 GO:0001101,GO:0008150,GO:0010033,GO:0033993,GO:0042221,GO:0046677,GO:0050896,GO:0070542,GO:1901700 - 0.000000000000000000000000000000000000000000000009436 178.0
TLS3_k127_2672025_0 Pfam:Zinicin_2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007128 619.0
TLS3_k127_2672025_1 Cell division protein FtsA K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 580.0
TLS3_k127_2672025_10 Major facilitator Superfamily - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000002809 233.0
TLS3_k127_2672025_11 phosphate binding protein K02040 - - 0.00000000000000000000000000000104 124.0
TLS3_k127_2672025_2 His Kinase A (phosphoacceptor) domain K07768 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006902 397.0
TLS3_k127_2672025_3 Epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 409.0
TLS3_k127_2672025_4 PhoU domain K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 368.0
TLS3_k127_2672025_5 ATPases associated with a variety of cellular activities K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 358.0
TLS3_k127_2672025_6 Transcriptional regulatory protein, C terminal K07776 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 346.0
TLS3_k127_2672025_7 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001697 277.0
TLS3_k127_2672025_8 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000004535 262.0
TLS3_k127_2672025_9 COG0581 ABC-type phosphate transport system, permease component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000001925 241.0
TLS3_k127_2712829_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 576.0
TLS3_k127_2712829_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 403.0
TLS3_k127_2712829_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 330.0
TLS3_k127_2712829_3 Mandelate Racemase Muconate Lactonizing - - - 0.000000000000000000000000000000000000000000000000000000000000000003906 236.0
TLS3_k127_2712829_4 Sterol carrier protein - - - 0.00000000000000000000000000000000000000000000000000000000009131 206.0
TLS3_k127_2712829_5 - - - - 0.000000002312 59.0
TLS3_k127_2729535_0 Penicillin amidase K07116 GO:0005575,GO:0005576 3.5.1.97 5.641e-314 992.0
TLS3_k127_2729535_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 6.967e-313 964.0
TLS3_k127_2729535_10 ABC 3 transport family K02075,K09819 - - 0.000000000000000000000000000000000000000000000000000000000001053 220.0
TLS3_k127_2729535_11 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.00000000000000000000000000000000000000000000000000000000001832 220.0
TLS3_k127_2729535_12 ABC transporter K11603 - - 0.00000000000000000000000000000000000000000000000001763 191.0
TLS3_k127_2729535_13 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000000000000000002692 192.0
TLS3_k127_2729535_14 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000002791 182.0
TLS3_k127_2729535_2 glutamine synthetase K01915 - 6.3.1.2 1.218e-254 790.0
TLS3_k127_2729535_3 Amidohydrolase family - - - 7.774e-249 780.0
TLS3_k127_2729535_4 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 516.0
TLS3_k127_2729535_5 YibE F family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 473.0
TLS3_k127_2729535_6 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 377.0
TLS3_k127_2729535_7 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008745 355.0
TLS3_k127_2729535_8 Belongs to the NUDIX hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 329.0
TLS3_k127_2729535_9 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000144 238.0
TLS3_k127_2751040_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 5.543e-290 895.0
TLS3_k127_2751040_1 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 473.0
TLS3_k127_2751040_2 COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component K02031,K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 446.0
TLS3_k127_2751040_3 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 348.0
TLS3_k127_2761639_0 DEAD-like helicases superfamily K03727 - - 0.0 1224.0
TLS3_k127_2761639_1 Pfam:DUF1446 - - - 8.122e-297 922.0
TLS3_k127_2761639_2 Carboxyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 511.0
TLS3_k127_2761639_3 Biotin carboxylase C-terminal domain K01959,K01965,K01968 - 6.4.1.1,6.4.1.3,6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 484.0
TLS3_k127_2761639_4 PFAM NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000000000001162 204.0
TLS3_k127_2761639_5 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000004732 170.0
TLS3_k127_2761639_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000001747 165.0
TLS3_k127_2761639_7 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000003532 142.0
TLS3_k127_2763366_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1089.0
TLS3_k127_2763366_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 7.012e-221 692.0
TLS3_k127_2763366_2 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000004281 237.0
TLS3_k127_2763366_3 protein conserved in bacteria - - - 0.0000000000000000001012 90.0
TLS3_k127_2763366_4 recombinase activity - - - 0.0001461 47.0
TLS3_k127_2769340_0 Von Willebrand factor K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006011 436.0
TLS3_k127_2769340_1 Toxic anion resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 368.0
TLS3_k127_2769340_2 - - - - 0.00000000000000008209 89.0
TLS3_k127_2769340_3 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000008418 59.0
TLS3_k127_2796428_0 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 518.0
TLS3_k127_2796428_1 protein conserved in bacteria K09927 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 483.0
TLS3_k127_2796428_2 Domain of unknown function DUF11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 360.0
TLS3_k127_2796428_3 Pfam Clp - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009502 297.0
TLS3_k127_2796428_4 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000006457 237.0
TLS3_k127_2796428_5 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000002403 201.0
TLS3_k127_2796428_6 Peptidoglycan-binding domain 1 protein K07260,K21449 - 3.4.17.14 0.0000000000000000000000000000000000000000000000004426 201.0
TLS3_k127_2796428_7 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000004173 186.0
TLS3_k127_2796428_8 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000005826 160.0
TLS3_k127_2796428_9 calcium- and calmodulin-responsive adenylate cyclase activity K07260 - 3.4.17.14 0.000000000000000000000000000000007287 148.0
TLS3_k127_2838998_0 Evidence 4 Homologs of previously reported genes of - - - 3.393e-235 736.0
TLS3_k127_2838998_1 Uncharacterized protein family (UPF0051) K09014 - - 1.472e-233 731.0
TLS3_k127_2838998_10 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 349.0
TLS3_k127_2838998_11 ATPases associated with a variety of cellular activities K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000000000000000003467 248.0
TLS3_k127_2838998_12 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136 - 0.00000000000000000000000000000000000000000000000000000000000002605 231.0
TLS3_k127_2838998_13 - - - - 0.000000000000000000000000000000000000000000000002103 189.0
TLS3_k127_2838998_14 - - - - 0.0000000000000000000000000000000000000005352 151.0
TLS3_k127_2838998_15 electron transfer activity K05337 GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.0000000000000000000000000000000000001249 147.0
TLS3_k127_2838998_16 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000000000000000000004828 143.0
TLS3_k127_2838998_17 Methylamine utilisation protein MauE - - - 0.00000000000000000000000000000000001557 145.0
TLS3_k127_2838998_18 - - - - 0.0000000000000000000000006204 105.0
TLS3_k127_2838998_19 nitrite transmembrane transporter activity K08177 - - 0.000000000000000000000002465 107.0
TLS3_k127_2838998_2 HpcH/HpaI aldolase/citrate lyase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 5.278e-211 659.0
TLS3_k127_2838998_20 Rieske-like [2Fe-2S] domain K05710 - - 0.00000000000000000007075 104.0
TLS3_k127_2838998_3 Peptidase, S9A B C family, catalytic domain protein K01354 - 3.4.21.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 579.0
TLS3_k127_2838998_4 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007778 498.0
TLS3_k127_2838998_5 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 467.0
TLS3_k127_2838998_6 Lysylphosphatidylglycerol synthase TM region K07027,K20468 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 473.0
TLS3_k127_2838998_7 endonuclease III K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 387.0
TLS3_k127_2838998_8 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 381.0
TLS3_k127_2838998_9 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 367.0
TLS3_k127_2862319_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1312.0
TLS3_k127_2862319_1 Glycosyltransferase like family 2 - - - 0.0 1297.0
TLS3_k127_2862319_10 ABC transporter transmembrane region K06147 - - 3.505e-277 862.0
TLS3_k127_2862319_11 ABC transporter transmembrane region K06147 - - 2.531e-275 860.0
TLS3_k127_2862319_12 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 3.418e-270 835.0
TLS3_k127_2862319_13 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 6.588e-258 804.0
TLS3_k127_2862319_14 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 2.478e-250 781.0
TLS3_k127_2862319_15 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 1.778e-232 726.0
TLS3_k127_2862319_16 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 5.317e-225 705.0
TLS3_k127_2862319_17 ThiF family - - - 3.443e-221 692.0
TLS3_k127_2862319_18 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 2.31e-214 686.0
TLS3_k127_2862319_19 e3 binding domain K00658 - 2.3.1.61 6.156e-204 646.0
TLS3_k127_2862319_2 Psort location CytoplasmicMembrane, score - - - 0.0 1220.0
TLS3_k127_2862319_20 polysaccharide biosynthetic process K01992 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0008150,GO:0009987,GO:0044764,GO:0046812,GO:0051704 - 1.54e-203 641.0
TLS3_k127_2862319_21 Aminotransferase class-III K01845 - 5.4.3.8 1.603e-199 630.0
TLS3_k127_2862319_22 DNA primase, small subunit - - - 3.134e-198 621.0
TLS3_k127_2862319_24 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 599.0
TLS3_k127_2862319_25 PFAM zinc finger SWIM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 591.0
TLS3_k127_2862319_26 glycosyl transferase group 1 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 567.0
TLS3_k127_2862319_27 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 537.0
TLS3_k127_2862319_28 VWA containing CoxE family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 544.0
TLS3_k127_2862319_29 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 532.0
TLS3_k127_2862319_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1036.0
TLS3_k127_2862319_30 Major facilitator Superfamily K08217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 514.0
TLS3_k127_2862319_31 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 503.0
TLS3_k127_2862319_32 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 489.0
TLS3_k127_2862319_33 Bacterial periplasmic substrate-binding proteins K02030,K10005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 487.0
TLS3_k127_2862319_34 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 474.0
TLS3_k127_2862319_35 acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 472.0
TLS3_k127_2862319_36 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 448.0
TLS3_k127_2862319_37 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 442.0
TLS3_k127_2862319_38 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 447.0
TLS3_k127_2862319_39 Malate dehydrogenase K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 432.0
TLS3_k127_2862319_4 Biotin carboxylase C-terminal domain K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 1.588e-309 957.0
TLS3_k127_2862319_40 permease, DMT superfamily K11939 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 422.0
TLS3_k127_2862319_41 amino acid transport K09970,K09971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 424.0
TLS3_k127_2862319_42 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 421.0
TLS3_k127_2862319_43 AAA domain, putative AbiEii toxin, Type IV TA system K02028,K09972,K10041 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008118 433.0
TLS3_k127_2862319_44 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 418.0
TLS3_k127_2862319_45 Cell envelope-related transcriptional attenuator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 410.0
TLS3_k127_2862319_46 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 395.0
TLS3_k127_2862319_47 Response regulator receiver K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 392.0
TLS3_k127_2862319_48 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 392.0
TLS3_k127_2862319_49 RmlD substrate binding domain K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 388.0
TLS3_k127_2862319_5 Non-essential cell division protein that could be required for efficient cell constriction - - - 2.696e-306 960.0
TLS3_k127_2862319_50 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 398.0
TLS3_k127_2862319_51 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 385.0
TLS3_k127_2862319_52 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 370.0
TLS3_k127_2862319_53 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 349.0
TLS3_k127_2862319_54 acyl-CoA hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 329.0
TLS3_k127_2862319_55 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 347.0
TLS3_k127_2862319_56 haloacid dehalogenase-like hydrolase K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009812 323.0
TLS3_k127_2862319_57 Belongs to the pirin family K06911 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 299.0
TLS3_k127_2862319_58 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 303.0
TLS3_k127_2862319_59 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004638 273.0
TLS3_k127_2862319_6 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.444e-298 921.0
TLS3_k127_2862319_60 DNA glycosylase K03649 - 3.2.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001841 278.0
TLS3_k127_2862319_61 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002734 276.0
TLS3_k127_2862319_62 dTDP-4-dehydrorhamnose 3,5-epimerase activity K00067,K01710,K01790 - 1.1.1.133,4.2.1.46,5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005251 267.0
TLS3_k127_2862319_63 Binding-protein-dependent transport system inner membrane component K02029,K10009,K17074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007702 285.0
TLS3_k127_2862319_64 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001899 261.0
TLS3_k127_2862319_65 nUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002787 258.0
TLS3_k127_2862319_66 GDP-mannose mannosyl hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007332 256.0
TLS3_k127_2862319_67 Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006104,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000001985 250.0
TLS3_k127_2862319_68 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000003198 239.0
TLS3_k127_2862319_7 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.105e-295 919.0
TLS3_k127_2862319_70 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000001852 229.0
TLS3_k127_2862319_71 - - - - 0.0000000000000000000000000000000000000000000000000000000000002116 214.0
TLS3_k127_2862319_72 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000003448 213.0
TLS3_k127_2862319_73 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000007084 191.0
TLS3_k127_2862319_74 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K14160 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - 0.000000000000000000000000000000000000000000000000231 184.0
TLS3_k127_2862319_75 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000006132 177.0
TLS3_k127_2862319_76 transporter K03298 - - 0.000000000000000000000000000000000000000000004938 177.0
TLS3_k127_2862319_77 endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000005329 167.0
TLS3_k127_2862319_78 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000249 181.0
TLS3_k127_2862319_79 flavin adenine dinucleotide binding - - - 0.0000000000000000000000000000000000000000006461 168.0
TLS3_k127_2862319_8 COG2015 Alkyl sulfatase and related hydrolases - - - 2.77e-291 907.0
TLS3_k127_2862319_81 Protein of unknown function (DUF4031) - - - 0.00000000000000000000000000000000000000001104 156.0
TLS3_k127_2862319_82 Acetyltransferase (GNAT) domain K03829 - - 0.00000000000000000000000000000000000000005152 158.0
TLS3_k127_2862319_83 PFAM regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000002462 172.0
TLS3_k127_2862319_84 arsenate reductase (glutaredoxin) activity K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.000000000000000000000000000000000000001292 149.0
TLS3_k127_2862319_86 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000331 126.0
TLS3_k127_2862319_88 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.0000000000000000000000007702 108.0
TLS3_k127_2862319_9 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 4.442e-291 902.0
TLS3_k127_2927730_0 Baseplate J-like protein - - - 1.59e-317 983.0
TLS3_k127_2927730_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.463e-294 909.0
TLS3_k127_2927730_10 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 578.0
TLS3_k127_2927730_11 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 567.0
TLS3_k127_2927730_12 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 556.0
TLS3_k127_2927730_13 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 547.0
TLS3_k127_2927730_14 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 463.0
TLS3_k127_2927730_15 PFAM AAA ATPase central domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 467.0
TLS3_k127_2927730_16 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 404.0
TLS3_k127_2927730_17 galactose-1-phosphate uridylyltransferase K00965 GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 388.0
TLS3_k127_2927730_18 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 379.0
TLS3_k127_2927730_19 TOBE domain K02017,K02018 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 357.0
TLS3_k127_2927730_2 Phage tail sheath C-terminal domain K06907 - - 1.613e-292 905.0
TLS3_k127_2927730_20 Protein of unknown function (DUF4255) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 336.0
TLS3_k127_2927730_21 Rhs element Vgr protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 349.0
TLS3_k127_2927730_22 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 324.0
TLS3_k127_2927730_23 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 293.0
TLS3_k127_2927730_24 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 283.0
TLS3_k127_2927730_25 Phage tail protein (Tail_P2_I) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001972 274.0
TLS3_k127_2927730_26 Pfam:DUF385 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001936 243.0
TLS3_k127_2927730_27 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000393 248.0
TLS3_k127_2927730_28 Molybdate ABC transporter K02017,K02018 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000001217 249.0
TLS3_k127_2927730_29 Domain of unknown function (DUF4157) - - - 0.000000000000000000000000000000000000000000000000000000000000000000384 261.0
TLS3_k127_2927730_3 Carboxypeptidase regulatory-like domain - - - 5.977e-273 879.0
TLS3_k127_2927730_30 Gene 25-like lysozyme K06903 - - 0.0000000000000000000000000000000000000000000000000000000000000000005961 235.0
TLS3_k127_2927730_31 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000000000000000000091 224.0
TLS3_k127_2927730_32 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000000000000009288 209.0
TLS3_k127_2927730_33 - - - - 0.00000000000000000000000000000000000000000000000000000000005171 209.0
TLS3_k127_2927730_34 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000006675 224.0
TLS3_k127_2927730_35 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 - 0.000000000000000000000000000000000000000000000000000000002098 209.0
TLS3_k127_2927730_36 3-methyladenine DNA glycosylase - - - 0.000000000000000000000000000000000000000000000000000000003485 217.0
TLS3_k127_2927730_37 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000000000004485 203.0
TLS3_k127_2927730_38 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000003072 211.0
TLS3_k127_2927730_39 - - - - 0.000000000000000000000000000000000000000000000000002135 185.0
TLS3_k127_2927730_4 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278,K00767 - 1.4.3.16,2.4.2.19 8.43e-271 843.0
TLS3_k127_2927730_40 Domain of unknown function (DUF4280) - - - 0.000000000000000000000000000000000000000000000004314 175.0
TLS3_k127_2927730_41 transcriptional regulator K19591 - - 0.000000000000000000000000000000000000000000003937 166.0
TLS3_k127_2927730_42 Septum formation - - - 0.00000000000000000000000000000000000000001805 164.0
TLS3_k127_2927730_43 Transcriptional regulator PadR-like family K10917 - - 0.0000000000000000000000000000000003394 138.0
TLS3_k127_2927730_45 - - - - 0.00000000000001588 81.0
TLS3_k127_2927730_46 mercury ion transmembrane transporter activity K07213 - - 0.0000000000002116 83.0
TLS3_k127_2927730_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 3.045e-265 822.0
TLS3_k127_2927730_6 Carboxypeptidase regulatory-like domain K20276 - - 2.443e-262 894.0
TLS3_k127_2927730_7 Heavy-metal-associated domain K17686 - 3.6.3.54 2.878e-236 758.0
TLS3_k127_2927730_8 ABC1 family - - - 3.102e-217 699.0
TLS3_k127_2927730_9 Carboxypeptidase regulatory-like domain - - - 2.388e-216 698.0
TLS3_k127_2931481_0 PFAM Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 368.0
TLS3_k127_2931481_1 Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009423 337.0
TLS3_k127_2931481_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000001479 218.0
TLS3_k127_2931481_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000457 202.0
TLS3_k127_2931481_4 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000003951 192.0
TLS3_k127_2931481_5 Belongs to the serpin family K13963 - - 0.0000000000000000000000000000000000004135 154.0
TLS3_k127_2931481_7 racemase K16841 - 5.1.99.3 0.0000008965 61.0
TLS3_k127_3020449_0 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007523 492.0
TLS3_k127_3020449_1 ABC transporter substrate-binding protein K02030,K02424,K17073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 429.0
TLS3_k127_3020449_2 amino acid ABC transporter K02029,K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 372.0
TLS3_k127_3020449_3 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.000000000000000001214 89.0
TLS3_k127_3020449_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000003306 83.0
TLS3_k127_3054788_0 AMP-binding enzyme C-terminal domain K00666 - - 4.093e-296 917.0
TLS3_k127_3054788_1 AAA domain, putative AbiEii toxin, Type IV TA system K02028,K02029 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 390.0
TLS3_k127_3054788_2 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016667,GO:0016684,GO:0019725,GO:0020012,GO:0030312,GO:0030682,GO:0042221,GO:0042592,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000001928 265.0
TLS3_k127_3054788_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000233 231.0
TLS3_k127_3054788_5 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000000000000004728 220.0
TLS3_k127_3054788_6 amino acid ABC transporter K02029,K02030 - - 0.000000000000000000000006397 101.0
TLS3_k127_3083081_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1124.0
TLS3_k127_3083081_1 LD-carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006293 529.0
TLS3_k127_3083081_2 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 481.0
TLS3_k127_3083081_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000003503 222.0
TLS3_k127_3083081_4 DoxX - - - 0.0000000000000000000000000000000000000007429 165.0
TLS3_k127_3083081_5 endonuclease activity - - - 0.0000005732 51.0
TLS3_k127_3091801_0 Rifampin ADP-ribosyl transferase K19062 - - 0.0000000000000000000000000000000000000000000000000000000000000001545 227.0
TLS3_k127_3091801_1 MOSC domain - - - 0.0000000000000000000000000000000000000000001839 167.0
TLS3_k127_3091801_2 endonuclease activity - - - 0.00000000000001215 78.0
TLS3_k127_3101649_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 7.081e-240 770.0
TLS3_k127_3101649_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 2.342e-230 716.0
TLS3_k127_3101649_10 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 339.0
TLS3_k127_3101649_11 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 327.0
TLS3_k127_3101649_12 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 324.0
TLS3_k127_3101649_13 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 304.0
TLS3_k127_3101649_14 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 289.0
TLS3_k127_3101649_15 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.0000000000000000000000000000000000000000000002029 178.0
TLS3_k127_3101649_16 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000003367 154.0
TLS3_k127_3101649_18 Lipoate-protein ligase - - - 0.0000000000000000000000000000000000000121 154.0
TLS3_k127_3101649_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.425e-222 701.0
TLS3_k127_3101649_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 5.062e-200 627.0
TLS3_k127_3101649_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 564.0
TLS3_k127_3101649_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 573.0
TLS3_k127_3101649_6 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007963 531.0
TLS3_k127_3101649_7 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 475.0
TLS3_k127_3101649_8 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 498.0
TLS3_k127_3101649_9 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 438.0
TLS3_k127_3137581_0 Glycosyl transferase family 2 K11936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 576.0
TLS3_k127_3137581_1 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 458.0
TLS3_k127_3137581_10 PFAM PHP domain K04477 - - 0.00000000000000000000000000000000000000000000000000015 200.0
TLS3_k127_3137581_11 adenylate kinase activity K00939 - 2.7.4.3 0.00000000000000000000000000000000000000003197 164.0
TLS3_k127_3137581_12 Sortase family - - - 0.0000000000000000000000000000000000000002364 158.0
TLS3_k127_3137581_13 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000000000000003965 156.0
TLS3_k127_3137581_14 Methyltransferase domain - - - 0.00000000000000000000000000000000124 143.0
TLS3_k127_3137581_15 Protein of unknown function (DUF4243) - - - 0.00000000000000002777 93.0
TLS3_k127_3137581_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 441.0
TLS3_k127_3137581_3 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 352.0
TLS3_k127_3137581_4 pyridoxamine 5-phosphate K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 331.0
TLS3_k127_3137581_5 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 298.0
TLS3_k127_3137581_6 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002681 285.0
TLS3_k127_3137581_7 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001862 278.0
TLS3_k127_3137581_8 ATP-grasp domain K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000001056 264.0
TLS3_k127_3137581_9 - - - - 0.00000000000000000000000000000000000000000000000000000003712 199.0
TLS3_k127_3138853_0 Homocysteine S-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 385.0
TLS3_k127_3138853_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000003618 224.0
TLS3_k127_3138853_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000002145 113.0
TLS3_k127_3138853_4 Pfam:Pyridox_oxidase - - - 0.0000000000000006375 86.0
TLS3_k127_3138853_5 Sugar efflux transporter for intercellular exchange K15383 - - 0.0000000000009422 74.0
TLS3_k127_3138853_6 Acetyltransferase (GNAT) domain - - - 0.0000000004681 68.0
TLS3_k127_3152142_0 Elongation factor G C-terminus K06207 - - 0.0 1030.0
TLS3_k127_3152142_1 Aminoacyl-tRNA editing domain K01881 - 6.1.1.15 6.449e-314 968.0
TLS3_k127_3152142_10 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 488.0
TLS3_k127_3152142_11 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 449.0
TLS3_k127_3152142_12 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 431.0
TLS3_k127_3152142_13 PFAM ExsB family protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000004459 246.0
TLS3_k127_3152142_14 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000000000000000000001575 220.0
TLS3_k127_3152142_15 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000006408 176.0
TLS3_k127_3152142_2 Protein synonym acyl-CoA synthetase K01897 - 6.2.1.3 3.483e-270 839.0
TLS3_k127_3152142_3 Participates in both transcription termination and antitermination K02600 - - 2.912e-217 696.0
TLS3_k127_3152142_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 613.0
TLS3_k127_3152142_5 geranylgeranyl reductase K21401 - 1.3.99.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 595.0
TLS3_k127_3152142_6 cytochrome p450 K16046 - 1.14.13.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 595.0
TLS3_k127_3152142_7 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 579.0
TLS3_k127_3152142_8 Alpha-L-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 584.0
TLS3_k127_3152142_9 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 469.0
TLS3_k127_340358_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 6.384e-275 867.0
TLS3_k127_340358_1 COGs COG1253 Hemolysins and related protein containing CBS domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 548.0
TLS3_k127_340358_10 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000005026 223.0
TLS3_k127_340358_11 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000002591 190.0
TLS3_k127_340358_12 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000002497 180.0
TLS3_k127_340358_13 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000001314 183.0
TLS3_k127_340358_14 YCII-related domain - - - 0.000000000000000000000000000000000000103 156.0
TLS3_k127_340358_15 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000008519 139.0
TLS3_k127_340358_16 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000007513 96.0
TLS3_k127_340358_17 Response regulator receiver modulated diguanylate cyclase phosphodiesterase - - - 0.0000000000000000005506 102.0
TLS3_k127_340358_18 - - - - 0.00000000000000002629 94.0
TLS3_k127_340358_19 response regulator K02479,K07684,K07685 - - 0.0000000000006043 82.0
TLS3_k127_340358_2 COGs COG1253 Hemolysins and related protein containing CBS domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007514 526.0
TLS3_k127_340358_20 SNARE associated Golgi protein K01077 - 3.1.3.1 0.000000001274 60.0
TLS3_k127_340358_3 phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000095 500.0
TLS3_k127_340358_4 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009474 437.0
TLS3_k127_340358_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 447.0
TLS3_k127_340358_6 rna polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 355.0
TLS3_k127_340358_7 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004797 340.0
TLS3_k127_340358_8 Glycosyl hydrolases family 16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 305.0
TLS3_k127_340358_9 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002362 260.0
TLS3_k127_3476681_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 402.0
TLS3_k127_3476681_1 Neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000001022 140.0
TLS3_k127_3493486_0 peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 360.0
TLS3_k127_3493486_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 305.0
TLS3_k127_3500893_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 8.8e-307 944.0
TLS3_k127_3507924_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 526.0
TLS3_k127_3507924_1 PAC2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 426.0
TLS3_k127_3507924_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 409.0
TLS3_k127_3534448_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008442 268.0
TLS3_k127_3534448_1 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000558 234.0
TLS3_k127_3534448_2 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000001389 79.0
TLS3_k127_3569065_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 624.0
TLS3_k127_3569065_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 450.0
TLS3_k127_3569065_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 373.0
TLS3_k127_3569065_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000003258 205.0
TLS3_k127_3569065_5 Sigma-70 region 2 - - - 0.000006082 55.0
TLS3_k127_3591965_0 C-terminal, D2-small domain, of ClpB protein K03695 - - 0.0 1415.0
TLS3_k127_3591965_1 Flavin-binding monooxygenase-like - - - 0.0 1281.0
TLS3_k127_3591965_10 ABC transporter (Permease) K02004 - - 1.189e-209 679.0
TLS3_k127_3591965_11 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 3.515e-209 657.0
TLS3_k127_3591965_12 drug exporters of the RND superfamily K06994 - - 3.355e-208 674.0
TLS3_k127_3591965_13 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 7.758e-200 642.0
TLS3_k127_3591965_14 SNF2 family N-terminal domain - - - 2.03e-196 653.0
TLS3_k127_3591965_15 Glycosyl transferase 4-like domain K15521 - 2.4.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 603.0
TLS3_k127_3591965_16 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 586.0
TLS3_k127_3591965_17 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 547.0
TLS3_k127_3591965_18 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009609 496.0
TLS3_k127_3591965_19 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 474.0
TLS3_k127_3591965_2 MMPL family K07003 - - 0.0 1227.0
TLS3_k127_3591965_20 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 470.0
TLS3_k127_3591965_21 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 464.0
TLS3_k127_3591965_22 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 452.0
TLS3_k127_3591965_23 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008004 442.0
TLS3_k127_3591965_24 transferase activity, transferring alkyl or aryl (other than methyl) groups K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 428.0
TLS3_k127_3591965_25 Thioesterase-like superfamily K10805 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 422.0
TLS3_k127_3591965_26 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 408.0
TLS3_k127_3591965_27 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 409.0
TLS3_k127_3591965_28 NAD FAD-dependent oxidoreductase K06955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 401.0
TLS3_k127_3591965_29 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 380.0
TLS3_k127_3591965_3 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 0.0 1093.0
TLS3_k127_3591965_30 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 362.0
TLS3_k127_3591965_31 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 357.0
TLS3_k127_3591965_32 FAD linked oxidases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 373.0
TLS3_k127_3591965_33 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 350.0
TLS3_k127_3591965_34 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 355.0
TLS3_k127_3591965_35 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 349.0
TLS3_k127_3591965_36 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 329.0
TLS3_k127_3591965_37 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 327.0
TLS3_k127_3591965_38 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 321.0
TLS3_k127_3591965_39 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 326.0
TLS3_k127_3591965_4 protein synonym multiple resistance and pH homeostasis protein A K00341,K05565,K14086 - 1.6.5.3 3.821e-293 922.0
TLS3_k127_3591965_40 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 322.0
TLS3_k127_3591965_41 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 314.0
TLS3_k127_3591965_42 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 302.0
TLS3_k127_3591965_43 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 306.0
TLS3_k127_3591965_44 transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 303.0
TLS3_k127_3591965_45 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 297.0
TLS3_k127_3591965_46 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 301.0
TLS3_k127_3591965_47 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001879 282.0
TLS3_k127_3591965_48 Protein of unknown function (DUF3445) K22342 - 1.14.13.238 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007236 281.0
TLS3_k127_3591965_49 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001002 290.0
TLS3_k127_3591965_5 monooxygenase - - - 9.527e-253 784.0
TLS3_k127_3591965_50 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002415 278.0
TLS3_k127_3591965_52 Protein of unknown function (DUF1349) K09702 - - 0.000000000000000000000000000000000000000000000000000000000000000000007961 239.0
TLS3_k127_3591965_53 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001078 229.0
TLS3_k127_3591965_55 Fatty acid hydroxylase superfamily K15746 - 1.14.15.24 0.0000000000000000000000000000000000000000000000000000000000002324 215.0
TLS3_k127_3591965_56 uroporphyrinogen-III synthase activity K01719,K01749,K02496,K13542,K13543 GO:0003674,GO:0003824,GO:0004852,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000004018 217.0
TLS3_k127_3591965_57 Putative bacterial sensory transduction regulator - - - 0.0000000000000000000000000000000000000000000000000000000003063 207.0
TLS3_k127_3591965_58 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000001527 202.0
TLS3_k127_3591965_59 - - - - 0.0000000000000000000000000000000000000000000000001126 180.0
TLS3_k127_3591965_6 Involved in the tonB-independent uptake of proteins - - - 1.035e-243 779.0
TLS3_k127_3591965_60 DNA-binding transcription factor activity K04096,K20421 - 2.1.1.303 0.0000000000000000000000000000000000000000000000003697 183.0
TLS3_k127_3591965_61 - - - - 0.000000000000000000000000000000000000000000000001451 182.0
TLS3_k127_3591965_62 protein phosphatase 2C domain protein - - - 0.000000000000000000000000000000000000000000005514 185.0
TLS3_k127_3591965_63 Multisubunit Na H antiporter MnhC subunit K05567 - - 0.00000000000000000000000000000000000000000002614 165.0
TLS3_k127_3591965_64 permease K03548 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000001208 174.0
TLS3_k127_3591965_65 Pfam Domain related to MnhB subunit of Na H antiporter K05565,K05566 - - 0.00000000000000000000000000000000000000001999 173.0
TLS3_k127_3591965_66 Putative zinc-finger - - - 0.0000000000000000000000000000001141 133.0
TLS3_k127_3591965_67 Na+/H+ ion antiporter subunit K05569 - - 0.00000000000000000000000002959 116.0
TLS3_k127_3591965_68 heme binding K06194,K21472 - - 0.00000000000000000000000991 110.0
TLS3_k127_3591965_69 monovalent cation:proton antiporter activity K05571 - - 0.00000000000000000002113 100.0
TLS3_k127_3591965_7 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 4.517e-226 721.0
TLS3_k127_3591965_70 Mo-molybdopterin cofactor metabolic process K03636,K21142 - 2.8.1.12 0.0000000000000005506 84.0
TLS3_k127_3591965_71 antiporter activity K05570 - - 0.000000000000009091 84.0
TLS3_k127_3591965_72 - - - - 0.0000000000000391 83.0
TLS3_k127_3591965_73 transcriptional regulator - - - 0.00000000002815 72.0
TLS3_k127_3591965_74 amine dehydrogenase activity - - - 0.0000000001117 74.0
TLS3_k127_3591965_76 PFAM peptidase - - - 0.000005097 59.0
TLS3_k127_3591965_77 Sigma-70 region 2 K03088 - - 0.000005917 57.0
TLS3_k127_3591965_8 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 4.249e-224 726.0
TLS3_k127_3591965_9 Aminotransferase class-III K01845 - 5.4.3.8 1.434e-214 676.0
TLS3_k127_3634849_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1172.0
TLS3_k127_3634849_1 DNA segregation ATPase FtsK SpoIIIE and related K03466 - - 4.664e-295 956.0
TLS3_k127_3634849_10 MerR, DNA binding K13639 - - 0.000000000000000000000000000000000000000000000000000000000001347 213.0
TLS3_k127_3634849_11 molybdopterin cofactor binding - - - 0.00000000000000000000000000000000000000000000000000000000001915 214.0
TLS3_k127_3634849_12 ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component - - - 0.000000000000000000000000000000000000000000002376 190.0
TLS3_k127_3634849_14 Ferric uptake regulator family K03711 - - 0.000000000000000000000008872 107.0
TLS3_k127_3634849_15 efflux transmembrane transporter activity K02004 - - 0.00002501 57.0
TLS3_k127_3634849_2 acyl-CoA dehydrogenase - - - 5.463e-213 668.0
TLS3_k127_3634849_3 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 568.0
TLS3_k127_3634849_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01459 - 3.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 421.0
TLS3_k127_3634849_5 PFAM Enoyl-CoA hydratase isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 357.0
TLS3_k127_3634849_6 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 362.0
TLS3_k127_3634849_7 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 316.0
TLS3_k127_3634849_8 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003454 239.0
TLS3_k127_3634849_9 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000001226 242.0
TLS3_k127_3635122_0 hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 302.0
TLS3_k127_3635122_1 HTH domain - - - 0.00000000000000000000000000000000000000000004773 168.0
TLS3_k127_3635122_2 PFAM Peptidase family M20 M25 M40 - - - 0.0000000000000000000000000000000000000000001989 168.0
TLS3_k127_3655770_0 nitrite transmembrane transporter activity K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 357.0
TLS3_k127_3655770_1 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005126 302.0
TLS3_k127_3655770_2 Aminoacyl-tRNA editing domain - - - 0.00000000000000000000000000000000000000000000000000000000000007044 220.0
TLS3_k127_3655770_3 - - - - 0.000000000000000000000000000000000000000000000000653 184.0
TLS3_k127_3655770_4 Phospholipase_D-nuclease N-terminal - - - 0.00000000000000000000000000000000000006684 145.0
TLS3_k127_3655770_5 FtsZ-dependent cytokinesis - - - 0.000000000000000000000000000000001119 143.0
TLS3_k127_3655770_6 transcriptional regulator - - - 0.00000000000006424 77.0
TLS3_k127_3655770_7 membrane protein of uknown function UCP014873 - - - 0.00002366 51.0
TLS3_k127_3705262_0 FAD binding domain K14672,K15972 - 1.14.13.200 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 478.0
TLS3_k127_3705262_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006781 261.0
TLS3_k127_3705262_2 Protein of unknown function (DUF2817) - - - 0.00000000000000000000000000000000000000006527 167.0
TLS3_k127_3705262_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000198 142.0
TLS3_k127_3705262_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000004263 84.0
TLS3_k127_3802149_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003359 274.0
TLS3_k127_3802149_1 Domain of unknown function (DUF3291) - - - 0.000000000000000000000000000000000000000000000000000003568 196.0
TLS3_k127_3822281_0 CoA binding domain - - - 8.319e-314 987.0
TLS3_k127_3822281_1 Peptidase dimerisation domain - - - 1.577e-231 725.0
TLS3_k127_3822281_10 transport, permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 367.0
TLS3_k127_3822281_11 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 329.0
TLS3_k127_3822281_12 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 316.0
TLS3_k127_3822281_13 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000718 302.0
TLS3_k127_3822281_14 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007677 258.0
TLS3_k127_3822281_15 PFAM globin K06886 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000006875 241.0
TLS3_k127_3822281_17 endonuclease activity - - - 0.0000000000000000000000004683 115.0
TLS3_k127_3822281_2 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K01661 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009844 548.0
TLS3_k127_3822281_3 acyl-CoA dehydrogenase K00248,K11410 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 536.0
TLS3_k127_3822281_4 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 505.0
TLS3_k127_3822281_5 DUF1704 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008458 457.0
TLS3_k127_3822281_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000718 409.0
TLS3_k127_3822281_7 formyltetrahydrofolate deformylase activity K00974,K01433 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006753,GO:0006760,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008864,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009256,GO:0009257,GO:0009259,GO:0009260,GO:0009396,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0034641,GO:0034654,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.72,3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006786 400.0
TLS3_k127_3822281_8 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 387.0
TLS3_k127_3822281_9 rRNA methyltransferase K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 371.0
TLS3_k127_3905806_0 PFAM binding-protein-dependent transport systems inner membrane component K10233 - - 9.578e-202 652.0
TLS3_k127_3905806_1 alpha amylase, catalytic K01187 - 3.2.1.20 3.558e-198 632.0
TLS3_k127_3905806_10 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 379.0
TLS3_k127_3905806_11 helix_turn _helix lactose operon repressor K05499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 376.0
TLS3_k127_3905806_12 Domain of unknown function (DUF4032) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 374.0
TLS3_k127_3905806_13 Periplasmic binding protein LacI transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 318.0
TLS3_k127_3905806_14 Bacterial extracellular solute-binding protein K15770 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007853 287.0
TLS3_k127_3905806_15 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000002731 239.0
TLS3_k127_3905806_2 Domain of unknown function (DUF4976) - - - 6.555e-198 622.0
TLS3_k127_3905806_3 ATPases associated with a variety of cellular activities K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 595.0
TLS3_k127_3905806_4 ABC transporter substrate-binding protein K10232 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 544.0
TLS3_k127_3905806_5 Beta-glucosidase K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 501.0
TLS3_k127_3905806_6 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K04091 - 1.14.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 484.0
TLS3_k127_3905806_7 PFAM binding-protein-dependent transport systems inner membrane component K10234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 469.0
TLS3_k127_3905806_8 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 438.0
TLS3_k127_3905806_9 inositol 2-dehydrogenase activity K00010 - 1.1.1.18,1.1.1.369 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 405.0
TLS3_k127_4027084_0 serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 1.515e-318 990.0
TLS3_k127_4027084_1 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 563.0
TLS3_k127_4027084_2 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 323.0
TLS3_k127_4027084_3 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 322.0
TLS3_k127_4027084_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001394 282.0
TLS3_k127_4027084_5 - - - - 0.000000000000000000000000000000006048 147.0
TLS3_k127_4027084_6 mevalonate kinase activity K00869,K00938,K16190 - 2.7.1.36,2.7.1.43,2.7.4.2 0.00000000000000000000001388 118.0
TLS3_k127_4027084_7 - - - - 0.0000000000000000001967 92.0
TLS3_k127_4027084_8 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000002251 88.0
TLS3_k127_4186036_0 CoA binding domain - - - 0.0 1106.0
TLS3_k127_4186036_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 5e-324 1002.0
TLS3_k127_4186036_10 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 427.0
TLS3_k127_4186036_11 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 325.0
TLS3_k127_4186036_12 transcriptional regulator K09017 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 306.0
TLS3_k127_4186036_13 homoserine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 300.0
TLS3_k127_4186036_14 Peptidase S16, lon domain protein K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000001405 259.0
TLS3_k127_4186036_15 Nickel-containing superoxide dismutase K00518 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001795 256.0
TLS3_k127_4186036_17 stress protein (general stress protein 26) - - - 0.00000000000000000000000000000000000000000000000000002369 203.0
TLS3_k127_4186036_18 thiolester hydrolase activity - - - 0.00000000000000000000000000000000008577 139.0
TLS3_k127_4186036_19 - - - - 0.000000000000000000000000000000009333 132.0
TLS3_k127_4186036_2 Oxidoreductase molybdopterin binding domain - - - 5.505e-200 638.0
TLS3_k127_4186036_20 - - - - 0.000000000000000000000000000003088 129.0
TLS3_k127_4186036_23 ThiS family K03154 - - 0.000000000000000001395 94.0
TLS3_k127_4186036_3 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 610.0
TLS3_k127_4186036_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 551.0
TLS3_k127_4186036_5 PP-loop family K21947 - 2.8.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 525.0
TLS3_k127_4186036_6 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006915 525.0
TLS3_k127_4186036_7 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 496.0
TLS3_k127_4186036_8 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 471.0
TLS3_k127_4186036_9 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 478.0
TLS3_k127_4265733_0 PFAM Major Facilitator Superfamily - - - 9.658e-226 711.0
TLS3_k127_4265733_1 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 534.0
TLS3_k127_4265733_10 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000005177 154.0
TLS3_k127_4265733_11 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000008483 147.0
TLS3_k127_4265733_12 triphosphatase activity - GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0050355 - 0.0000000000000000000000000000004411 139.0
TLS3_k127_4265733_13 Domain of unknown function (DUF1971) - - - 0.00000001574 64.0
TLS3_k127_4265733_14 - - - - 0.000006919 55.0
TLS3_k127_4265733_2 Domain of unknown function (DUF222) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 472.0
TLS3_k127_4265733_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 421.0
TLS3_k127_4265733_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008907 323.0
TLS3_k127_4265733_5 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 319.0
TLS3_k127_4265733_6 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000004341 267.0
TLS3_k127_4265733_7 Serine phosphatase RsbU, regulator of sigma subunit - - - 0.00000000000000000000000000000000000000000000000000000000001259 231.0
TLS3_k127_4265733_8 - - - - 0.000000000000000000000000000000000000000000000000000003037 207.0
TLS3_k127_4265733_9 CHAD - - - 0.00000000000000000000000000000000000000000000004212 188.0
TLS3_k127_4268799_0 hydrolase, family 3 K05349 - 3.2.1.21 0.0 1125.0
TLS3_k127_4268799_1 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.0 1005.0
TLS3_k127_4268799_10 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 412.0
TLS3_k127_4268799_11 Protein of unknown function (DUF418) K07148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 408.0
TLS3_k127_4268799_12 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 391.0
TLS3_k127_4268799_13 Virulence factor BrkB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 368.0
TLS3_k127_4268799_14 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 349.0
TLS3_k127_4268799_15 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 351.0
TLS3_k127_4268799_16 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009455 325.0
TLS3_k127_4268799_17 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 298.0
TLS3_k127_4268799_18 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001654 291.0
TLS3_k127_4268799_19 Electron transfer flavoprotein alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001883 256.0
TLS3_k127_4268799_2 Belongs to the N(4) N(6)-methyltransferase family K00571,K00590 - 2.1.1.113,2.1.1.72 1.382e-203 649.0
TLS3_k127_4268799_20 electron transfer flavoprotein-ubiquinone oxidoreductase - - - 0.00000000000000000000000000000000000006489 161.0
TLS3_k127_4268799_21 RNA polymerase sigma-24 subunit, ECF subfamily - - - 0.00000000000000000000000000000000003969 153.0
TLS3_k127_4268799_22 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000007521 140.0
TLS3_k127_4268799_23 PFAM extracellular solute-binding protein family 1 K11069 - - 0.00000000000000001218 88.0
TLS3_k127_4268799_3 Belongs to the aldehyde dehydrogenase family K00137 - 1.2.1.19 7.172e-194 629.0
TLS3_k127_4268799_4 heme binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006536 617.0
TLS3_k127_4268799_5 geranylgeranyl reductase activity K00313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 594.0
TLS3_k127_4268799_6 non-haem dioxygenase in morphine synthesis N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 546.0
TLS3_k127_4268799_7 1-aminocyclopropane-1-carboxylate deaminase K01505,K05396,K17950 - 3.5.99.7,4.4.1.15,4.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 453.0
TLS3_k127_4268799_8 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 430.0
TLS3_k127_4268799_9 Alanine racemase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 409.0
TLS3_k127_4343636_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096 2.7.7.59 0.0 1065.0
TLS3_k127_4343636_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.818e-259 808.0
TLS3_k127_4343636_10 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001584 287.0
TLS3_k127_4343636_11 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003556 249.0
TLS3_k127_4343636_12 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000007235 253.0
TLS3_k127_4343636_13 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000227 244.0
TLS3_k127_4343636_14 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000003349 195.0
TLS3_k127_4343636_15 ThiS family K03636 - - 0.000000000000000000000000000000000000002196 160.0
TLS3_k127_4343636_2 Glycerate kinase family K00865 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 451.0
TLS3_k127_4343636_3 PAC2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 446.0
TLS3_k127_4343636_4 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 396.0
TLS3_k127_4343636_5 Belongs to the peptidase S16 family K07177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 396.0
TLS3_k127_4343636_6 regulation of cell shape K04074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 370.0
TLS3_k127_4343636_7 Chlorite dismutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 340.0
TLS3_k127_4343636_8 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 345.0
TLS3_k127_4343636_9 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 316.0
TLS3_k127_4352001_0 PFAM Peptidoglycan-binding LysM - - - 4.611e-293 935.0
TLS3_k127_4352001_1 Type ii secretion system protein e K02283 - - 3.383e-221 706.0
TLS3_k127_4352001_13 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000002088 117.0
TLS3_k127_4352001_16 aspartic-type endopeptidase activity K02278,K02654 - 3.4.23.43 0.0000000000000000001643 97.0
TLS3_k127_4352001_2 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 413.0
TLS3_k127_4352001_3 Protein of unknown function (DUF429) K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 362.0
TLS3_k127_4352001_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008612 349.0
TLS3_k127_4352001_5 Type ii secretion system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 329.0
TLS3_k127_4352001_6 Type II secretion system (T2SS), protein F K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 294.0
TLS3_k127_4352001_7 SAF - - - 0.0000000000000000000000000000000000000000000000000000005773 203.0
TLS3_k127_4352001_8 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.00000000000000000000000000000000000000000000005639 173.0
TLS3_k127_4362114_0 alpha-galactosidase K07407 - 3.2.1.22 6.619e-307 952.0
TLS3_k127_4362114_1 HD domain K07814 - - 7.124e-270 860.0
TLS3_k127_4362114_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 386.0
TLS3_k127_4362114_11 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 398.0
TLS3_k127_4362114_12 transport, permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 381.0
TLS3_k127_4362114_13 Bacterial extracellular solute-binding protein K10117 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 378.0
TLS3_k127_4362114_14 PFAM binding-protein-dependent transport systems inner membrane component K10118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 339.0
TLS3_k127_4362114_15 ABC-type sugar transport system, permease component K02026,K10119,K17243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 322.0
TLS3_k127_4362114_16 Rubrerythrin K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 315.0
TLS3_k127_4362114_17 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 320.0
TLS3_k127_4362114_18 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 317.0
TLS3_k127_4362114_19 Esterase K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 309.0
TLS3_k127_4362114_2 Belongs to the glycosyl hydrolase 3 family - - - 5.919e-266 841.0
TLS3_k127_4362114_20 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002117 282.0
TLS3_k127_4362114_21 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000006184 253.0
TLS3_k127_4362114_22 Thioesterase K07107 - - 0.0000000000000000000000000000000000000000000000000000000000000005053 224.0
TLS3_k127_4362114_23 polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000003957 220.0
TLS3_k127_4362114_24 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.0000000000000000000000000000000000000000000000000000000004433 207.0
TLS3_k127_4362114_25 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.0000000000000000000000000000000000000000000000000000004641 212.0
TLS3_k127_4362114_26 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000155 199.0
TLS3_k127_4362114_27 permease K20469 - - 0.0000000000000000000000000000000000000000000000000004735 198.0
TLS3_k127_4362114_28 COG2513 PEP phosphonomutase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000007956 194.0
TLS3_k127_4362114_29 4fe-4S ferredoxin, iron-sulfur binding domain protein K03616 - - 0.0000000000000000000000000000000000000000000000000009397 190.0
TLS3_k127_4362114_3 Belongs to the thiolase family - - - 1.473e-223 696.0
TLS3_k127_4362114_30 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000005328 142.0
TLS3_k127_4362114_31 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000005235 143.0
TLS3_k127_4362114_32 Protein of unknown function (DUF3237) - - - 0.0000000000000000000000000000003545 127.0
TLS3_k127_4362114_33 Cobalamin B12-binding domain protein - - - 0.00000000000000000000000000001439 128.0
TLS3_k127_4362114_36 Bacterial regulatory proteins, tetR family - - - 0.00000000000000001297 91.0
TLS3_k127_4362114_37 - - - - 0.0000000000002811 83.0
TLS3_k127_4362114_38 Universal stress protein family - - - 0.000000000219 68.0
TLS3_k127_4362114_39 Protein of unknown function (DUF664) - - - 0.00004278 53.0
TLS3_k127_4362114_4 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008798 601.0
TLS3_k127_4362114_5 Daunorubicin resistance ABC transporter ATP-binding subunit K01990,K18232 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006558 444.0
TLS3_k127_4362114_6 FAD linked oxidase domain protein K00594 - 1.1.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 412.0
TLS3_k127_4362114_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 402.0
TLS3_k127_4362114_8 Short-chain dehydrogenase reductase sdr K14633 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 400.0
TLS3_k127_4362114_9 Peptidase family M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 396.0
TLS3_k127_4432504_0 E1-E2 ATPase K12952 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 479.0
TLS3_k127_4432504_1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950,K13940 - 2.7.6.3,4.1.2.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 404.0
TLS3_k127_4432504_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 346.0
TLS3_k127_4432504_3 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 305.0
TLS3_k127_4432504_4 alpha-ribazole phosphatase activity K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000003237 221.0
TLS3_k127_4432504_5 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000003165 173.0
TLS3_k127_4493012_0 Ion channel K10716 - - 1.233e-263 824.0
TLS3_k127_4493012_1 F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 524.0
TLS3_k127_4493012_2 Asp/Glu/Hydantoin racemase K01779 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000001201 268.0
TLS3_k127_4493012_3 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000006396 221.0
TLS3_k127_4493012_4 Cytochrome P450 - GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016125,GO:0016491,GO:0030312,GO:0044238,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901615 - 0.000000000000000000000000000000000000000008373 171.0
TLS3_k127_4493012_5 Ribosomal RNA adenine dimethylase - - - 0.0000000000000000000000000000000000000003565 152.0
TLS3_k127_4493012_6 Domain of unknown function (DUF1971) - - - 0.00000000000000000000891 94.0
TLS3_k127_4523401_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 537.0
TLS3_k127_4523401_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 368.0
TLS3_k127_4523401_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 357.0
TLS3_k127_4523401_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005097 238.0
TLS3_k127_4523401_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000000002444 222.0
TLS3_k127_4523401_5 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000000002312 210.0
TLS3_k127_4523401_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071944 - 0.00000000000000000000000000000001741 126.0
TLS3_k127_4523401_7 Ribosomal protein L36 K02919 - - 0.000000000000000007659 82.0
TLS3_k127_4538613_0 saccharopine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001273 270.0
TLS3_k127_4538613_1 Lysophospholipase K01048 - 3.1.1.5 0.0000000000000000001563 99.0
TLS3_k127_4556600_0 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 462.0
TLS3_k127_4556600_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000543 204.0
TLS3_k127_4556600_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000001255 187.0
TLS3_k127_4556600_3 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000004996 160.0
TLS3_k127_4556600_4 Small Multidrug Resistance protein K11741 - - 0.0000000000000000000000000000001887 128.0
TLS3_k127_4556600_5 Pfam:DUF1049 - - - 0.0002615 48.0
TLS3_k127_4680748_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 1.54e-260 811.0
TLS3_k127_4680748_1 Aminotransferase class I and II K14261 - - 1.002e-243 754.0
TLS3_k127_4680748_10 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 471.0
TLS3_k127_4680748_11 ROK family K00845,K00886 - 2.7.1.2,2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009442 456.0
TLS3_k127_4680748_12 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 452.0
TLS3_k127_4680748_13 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 434.0
TLS3_k127_4680748_14 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 390.0
TLS3_k127_4680748_15 RNA-binding protein containing a PIN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 387.0
TLS3_k127_4680748_16 endonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 324.0
TLS3_k127_4680748_17 GHMP kinases N terminal domain K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 301.0
TLS3_k127_4680748_18 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 290.0
TLS3_k127_4680748_19 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139,K01752,K01754 - 2.7.6.5,3.1.7.2,4.3.1.17,4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000361 266.0
TLS3_k127_4680748_2 EXOIII K02342 - 2.7.7.7 4.888e-227 715.0
TLS3_k127_4680748_20 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000001073 257.0
TLS3_k127_4680748_21 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000002952 224.0
TLS3_k127_4680748_23 PFAM Sporulation and spore germination - - - 0.00000000000000000000000000000000000000000000000003444 188.0
TLS3_k127_4680748_27 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000002458 130.0
TLS3_k127_4680748_29 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.00000000000000000000000000003695 119.0
TLS3_k127_4680748_3 Histidine kinase - - - 1.619e-222 700.0
TLS3_k127_4680748_32 - - - - 0.000000000000001671 80.0
TLS3_k127_4680748_33 - - - - 0.000002359 57.0
TLS3_k127_4680748_4 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 2.69e-200 636.0
TLS3_k127_4680748_5 Glycosyl transferases group 1 K13668 - 2.4.1.346 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000938 612.0
TLS3_k127_4680748_6 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 589.0
TLS3_k127_4680748_7 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 536.0
TLS3_k127_4680748_8 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 498.0
TLS3_k127_4680748_9 FAD linked K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 484.0
TLS3_k127_4757278_0 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 315.0
TLS3_k127_4757278_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K15942,K21172 - 2.1.1.288 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 323.0
TLS3_k127_4757278_2 COGs COG1819 Glycosyl transferase related to UDP-glucuronosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001491 239.0
TLS3_k127_4757278_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000002309 217.0
TLS3_k127_4757278_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000004192 190.0
TLS3_k127_4785420_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1253.0
TLS3_k127_4785420_1 FAD dependent oxidoreductase - - - 6.401e-237 748.0
TLS3_k127_4785420_10 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 339.0
TLS3_k127_4785420_11 phosphoribosyltransferase K07101 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 282.0
TLS3_k127_4785420_12 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001864 291.0
TLS3_k127_4785420_13 Product type t transporter K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002422 270.0
TLS3_k127_4785420_14 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000004946 255.0
TLS3_k127_4785420_15 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000001727 248.0
TLS3_k127_4785420_16 YjbR - - - 0.0000000000000000000000000000000000000000000000000000005538 198.0
TLS3_k127_4785420_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.891e-225 710.0
TLS3_k127_4785420_3 Luciferase-like monooxygenase - - - 9.365e-218 680.0
TLS3_k127_4785420_4 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 525.0
TLS3_k127_4785420_5 cytosine deaminase K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 513.0
TLS3_k127_4785420_6 Belongs to the peptidase M50B family - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 477.0
TLS3_k127_4785420_7 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 439.0
TLS3_k127_4785420_8 Creatininase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 418.0
TLS3_k127_4785420_9 Xanthine dehydrogenase iron-sulfur cluster and FAD-binding subunit A K13481 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 366.0
TLS3_k127_4801698_0 MMPL family K06994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 617.0
TLS3_k127_4801698_1 Predicted membrane protein (DUF2254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 431.0
TLS3_k127_4801698_10 glycerophosphodiester transmembrane transport K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008928 260.0
TLS3_k127_4801698_11 Alpha beta hydrolase fold K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000001416 248.0
TLS3_k127_4801698_12 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001661 250.0
TLS3_k127_4801698_13 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000247 235.0
TLS3_k127_4801698_14 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000157 225.0
TLS3_k127_4801698_15 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000008195 213.0
TLS3_k127_4801698_16 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000002184 169.0
TLS3_k127_4801698_17 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000007314 161.0
TLS3_k127_4801698_18 Histidine kinase - - - 0.00000000000000000000000000000000000000001034 176.0
TLS3_k127_4801698_19 Cupin - - - 0.00000000000000000000000000000000007269 137.0
TLS3_k127_4801698_2 ATPases associated with a variety of cellular activities K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 418.0
TLS3_k127_4801698_21 SnoaL-like domain - - - 0.0000000000000000002476 93.0
TLS3_k127_4801698_22 - - - - 0.000000000000000001507 94.0
TLS3_k127_4801698_23 glyoxalase III activity - - - 0.000000000001482 68.0
TLS3_k127_4801698_24 zinc ion binding K06204 - - 0.00000000001858 68.0
TLS3_k127_4801698_25 - - - - 0.00000006922 59.0
TLS3_k127_4801698_3 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 392.0
TLS3_k127_4801698_4 dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 352.0
TLS3_k127_4801698_5 PFAM extracellular solute-binding protein family 1 K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 327.0
TLS3_k127_4801698_6 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 296.0
TLS3_k127_4801698_7 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002668 258.0
TLS3_k127_4801698_8 Acetyltransferase (GNAT) domain K00663,K03790 - 2.3.1.128,2.3.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000003299 262.0
TLS3_k127_4801698_9 DeoR C terminal sensor domain K02081,K03436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004253 255.0
TLS3_k127_480789_0 Glycosyltransferases, probably involved in cell wall biogenesis - - - 7.218e-244 782.0
TLS3_k127_480789_1 DbpA RNA binding domain K05592,K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 1.654e-214 680.0
TLS3_k127_480789_10 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000007688 226.0
TLS3_k127_480789_11 Cyclase dehydrase - - - 0.000000000000000000000000000000000000000000000000000000000001948 216.0
TLS3_k127_480789_12 Cupin 4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000009343 224.0
TLS3_k127_480789_13 - - - - 0.0000000000000000000000000000000000000000000000000001639 205.0
TLS3_k127_480789_14 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000003172 189.0
TLS3_k127_480789_15 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000003919 159.0
TLS3_k127_480789_16 ferredoxin K05337 - - 0.000000000000000000000000002688 115.0
TLS3_k127_480789_18 CsbD-like - - - 0.000000000000001804 85.0
TLS3_k127_480789_19 Domain of unknown function (DUF3459) K01236 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016787,GO:0016798,GO:0030978,GO:0030980,GO:0033942,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0071704,GO:1901575,GO:1901576 3.2.1.141 0.00001781 51.0
TLS3_k127_480789_2 Malto-oligosyl trehalose synthase K06044 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576 5.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 561.0
TLS3_k127_480789_3 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 462.0
TLS3_k127_480789_4 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 407.0
TLS3_k127_480789_5 metal-dependent hydrolase of the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008225 397.0
TLS3_k127_480789_6 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 347.0
TLS3_k127_480789_7 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000001397 265.0
TLS3_k127_480789_8 pfkB family carbohydrate kinase K00882 - 2.7.1.56 0.00000000000000000000000000000000000000000000000000000000000000000001169 252.0
TLS3_k127_480789_9 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000000000000000000000000001382 234.0
TLS3_k127_4914014_0 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 335.0
TLS3_k127_4914014_1 transcriptional regulators - - - 0.000000000000000000000000000000000001418 142.0
TLS3_k127_4914014_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000002059 130.0
TLS3_k127_4914374_0 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001259 287.0
TLS3_k127_4914374_1 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008034 278.0
TLS3_k127_4914374_2 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003516 271.0
TLS3_k127_4914374_3 cAMP biosynthetic process K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000106 238.0
TLS3_k127_4914374_4 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000001497 225.0
TLS3_k127_4914374_5 YjbR - - - 0.0000000000000000000000000000000000000000000000000107 187.0
TLS3_k127_4914374_6 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000005319 158.0
TLS3_k127_4914374_7 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.000000000000000000004639 103.0
TLS3_k127_4914374_8 Domain of unknown function (DUF222) - - - 0.00000072 56.0
TLS3_k127_4921591_0 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000009118 228.0
TLS3_k127_4921591_1 amino acid transport K02030 - - 0.000000000000000000000000000000000000000000000000002071 194.0
TLS3_k127_4921591_2 Polar amino acid transport system K02028 - 3.6.3.21 0.00000000000000000000000000000000001534 139.0
TLS3_k127_495748_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1215.0
TLS3_k127_495748_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1015.0
TLS3_k127_495748_10 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 323.0
TLS3_k127_495748_11 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 294.0
TLS3_k127_495748_12 endonuclease activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006181 266.0
TLS3_k127_495748_13 Preprotein translocase subunit YajC K03210 - - 0.000000000000000000000000000000000000000008061 157.0
TLS3_k127_495748_14 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000003875 158.0
TLS3_k127_495748_16 single-stranded DNA binding K03111 - - 0.000000000000000000000001224 107.0
TLS3_k127_495748_2 Histidyl-tRNA synthetase K01892 - 6.1.1.21 5.138e-203 642.0
TLS3_k127_495748_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 3.803e-196 628.0
TLS3_k127_495748_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 581.0
TLS3_k127_495748_5 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000782 552.0
TLS3_k127_495748_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 446.0
TLS3_k127_495748_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 433.0
TLS3_k127_495748_8 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 394.0
TLS3_k127_495748_9 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 349.0
TLS3_k127_4960553_0 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006972 597.0
TLS3_k127_4960553_1 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 546.0
TLS3_k127_4960553_2 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 464.0
TLS3_k127_4960553_3 Anion-transporting ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 330.0
TLS3_k127_4960553_4 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000002884 194.0
TLS3_k127_5003104_0 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001054 259.0
TLS3_k127_5003104_1 endonuclease activity - - - 0.0000000000000000000000000000000000000000000000000000000000001611 231.0
TLS3_k127_5003104_2 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000009094 189.0
TLS3_k127_5003104_3 Domain of unknown function (DU1801) - - - 0.000000000000000000009675 93.0
TLS3_k127_5075745_0 Glycosyl transferase 4-like domain - - - 2.146e-244 758.0
TLS3_k127_5075745_1 PFAM Glycoside hydrolase 15-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 574.0
TLS3_k127_5075745_2 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 447.0
TLS3_k127_5075745_3 converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000003671 244.0
TLS3_k127_5075745_4 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000001541 213.0
TLS3_k127_5095485_0 Proline dehydrogenase K13821 - 1.2.1.88,1.5.5.2 0.0 1273.0
TLS3_k127_5095485_1 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1158.0
TLS3_k127_5095485_10 Transcriptional regulator - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0044419,GO:0044464,GO:0050789,GO:0050794,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 344.0
TLS3_k127_5095485_11 protein deglycation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 329.0
TLS3_k127_5095485_12 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 315.0
TLS3_k127_5095485_13 Mg2 transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000009365 246.0
TLS3_k127_5095485_14 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000004365 216.0
TLS3_k127_5095485_15 AsnC family - - - 0.000000000000000000000000000000000000000195 155.0
TLS3_k127_5095485_16 RNA polymerase sigma factor, sigma-70 family - - - 0.00000000000000000000000000000001723 144.0
TLS3_k127_5095485_17 UPF0126 domain - - - 0.00000000000000000000001676 110.0
TLS3_k127_5095485_18 Glyoxalase-like domain - - - 0.0000000000000000000008526 111.0
TLS3_k127_5095485_19 transcriptional regulator - - - 0.0000000000000000007929 92.0
TLS3_k127_5095485_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 GO:0000271,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901576 2.7.7.27 1.027e-227 709.0
TLS3_k127_5095485_20 - - - - 0.0000000000000003898 85.0
TLS3_k127_5095485_21 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000004976 78.0
TLS3_k127_5095485_22 Belongs to the peptidase S8 family - - - 0.0000008019 51.0
TLS3_k127_5095485_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 6.514e-195 634.0
TLS3_k127_5095485_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 589.0
TLS3_k127_5095485_5 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 475.0
TLS3_k127_5095485_6 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K03778 - 1.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 454.0
TLS3_k127_5095485_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 404.0
TLS3_k127_5095485_8 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 378.0
TLS3_k127_5095485_9 Alpha beta hydrolase K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 356.0
TLS3_k127_5119604_0 Rieske 2Fe-2S K14952 - - 1.121e-264 822.0
TLS3_k127_5119604_1 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 557.0
TLS3_k127_5119604_10 cellular response to DNA damage stimulus K07340 - - 0.00000000000000000000000000000000000000000000000000002412 194.0
TLS3_k127_5119604_11 Redoxin - - - 0.00000000000000000000000000000000000000000000000064 196.0
TLS3_k127_5119604_13 SMART regulatory protein LuxR - - - 0.0000000000000000000000000000000000309 142.0
TLS3_k127_5119604_14 Protein of unknown function (DUF2510) - - - 0.00000000000000000000006271 108.0
TLS3_k127_5119604_15 Required for disulfide bond formation in some proteins K03611 - - 0.000000000000000000002961 109.0
TLS3_k127_5119604_16 antisigma factor binding K04749 - - 0.0000000000000002916 85.0
TLS3_k127_5119604_17 sigma factor antagonist activity K04757 - 2.7.11.1 0.0000000000000006317 83.0
TLS3_k127_5119604_2 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 547.0
TLS3_k127_5119604_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 454.0
TLS3_k127_5119604_5 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 439.0
TLS3_k127_5119604_6 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 323.0
TLS3_k127_5119604_7 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 323.0
TLS3_k127_5119604_8 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000001448 280.0
TLS3_k127_5119604_9 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000007386 220.0
TLS3_k127_5127719_0 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 429.0
TLS3_k127_5127719_1 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.0000000000000000000000000000000000000000000000000000000000000000000822 252.0
TLS3_k127_5127719_2 Domain of unknown function (DUF222) - - - 0.0000000000000000000000000000000000000000000000000000000000001852 218.0
TLS3_k127_5127719_3 cytidine deaminase activity K01489 - 3.5.4.5 0.00000000000000000000000000000000000000000327 158.0
TLS3_k127_5127719_4 helix_turn_helix ASNC type - - - 0.000000000000000000000000001112 123.0
TLS3_k127_5165947_0 ABC transporter - - - 3.594e-282 873.0
TLS3_k127_5165947_1 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 2.97e-275 860.0
TLS3_k127_5165947_10 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 340.0
TLS3_k127_5165947_11 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 327.0
TLS3_k127_5165947_12 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007968 326.0
TLS3_k127_5165947_13 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002544 286.0
TLS3_k127_5165947_14 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000887 261.0
TLS3_k127_5165947_15 Putative FMN-binding domain K07734 - - 0.00000000000000000000000000000000000000000000000000000000000000001543 233.0
TLS3_k127_5165947_16 mechanosensitive ion channel activity K03282 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.000000000000000000000000000000000002666 141.0
TLS3_k127_5165947_18 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000009871 68.0
TLS3_k127_5165947_2 spermidine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 559.0
TLS3_k127_5165947_3 F420-dependent oxidoreductase, MSMEG_3544 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 469.0
TLS3_k127_5165947_4 Alpha/beta hydrolase family - GO:0000287,GO:0001676,GO:0002532,GO:0002538,GO:0002539,GO:0003008,GO:0003013,GO:0003674,GO:0003824,GO:0004301,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006725,GO:0006793,GO:0006796,GO:0006950,GO:0006952,GO:0006954,GO:0007600,GO:0008015,GO:0008150,GO:0008152,GO:0008217,GO:0009056,GO:0009810,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0015643,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016801,GO:0016803,GO:0018742,GO:0018904,GO:0019216,GO:0019218,GO:0019222,GO:0019233,GO:0019439,GO:0019752,GO:0030258,GO:0032501,GO:0032787,GO:0033559,GO:0042577,GO:0042578,GO:0042579,GO:0042592,GO:0042632,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043651,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045777,GO:0046272,GO:0046483,GO:0046839,GO:0046872,GO:0046983,GO:0048518,GO:0048878,GO:0050789,GO:0050877,GO:0050896,GO:0055088,GO:0055092,GO:0060255,GO:0062012,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090181,GO:0097176,GO:1900673,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 450.0
TLS3_k127_5165947_5 Sodium/hydrogen exchanger family K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 446.0
TLS3_k127_5165947_6 Daunorubicin resistance ABC transporter ATP-binding subunit K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 409.0
TLS3_k127_5165947_7 Beta propeller domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 389.0
TLS3_k127_5165947_8 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009023 377.0
TLS3_k127_5165947_9 Short-chain dehydrogenase reductase sdr K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 351.0
TLS3_k127_5168925_0 phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 1.212e-248 779.0
TLS3_k127_5168925_1 phytoene desaturase - - - 1.6e-199 632.0
TLS3_k127_5168925_10 Polyprenyl synthetase K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000006967 109.0
TLS3_k127_5168925_11 Domain of unknown function (DUF4440) - - - 0.00000000004925 74.0
TLS3_k127_5168925_12 Multicopper oxidase K04753 - - 0.000004001 54.0
TLS3_k127_5168925_2 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 501.0
TLS3_k127_5168925_3 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 461.0
TLS3_k127_5168925_4 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 438.0
TLS3_k127_5168925_5 spheroidene monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 332.0
TLS3_k127_5168925_6 Carotenoid biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 310.0
TLS3_k127_5168925_7 Aminoglycoside 3-N-acetyltransferase K00662 - 2.3.1.81 0.0000000000000000000000000000000000000000000000000000000000000000005396 243.0
TLS3_k127_5168925_8 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000177 234.0
TLS3_k127_5168925_9 peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000000000000000000000001537 134.0
TLS3_k127_5173467_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1316.0
TLS3_k127_5173467_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1106.0
TLS3_k127_5173467_10 hydrolase K01091 GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0071704,GO:0140096,GO:1901564 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000306 280.0
TLS3_k127_5173467_11 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001057 257.0
TLS3_k127_5173467_12 cell cycle K05589,K13052 - - 0.000000000000000000000000000000000000000000000000002621 186.0
TLS3_k127_5173467_13 - - - - 0.000000000000000000000000000000000000000000000000004042 188.0
TLS3_k127_5173467_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 1.444e-307 985.0
TLS3_k127_5173467_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 6.127e-231 745.0
TLS3_k127_5173467_4 MazG nucleotide pyrophosphohydrolase domain K02499 - - 5.328e-226 711.0
TLS3_k127_5173467_5 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 445.0
TLS3_k127_5173467_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 321.0
TLS3_k127_5173467_8 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 316.0
TLS3_k127_5173467_9 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003694 278.0
TLS3_k127_5193626_0 Peptidase family M1 domain K08776 - - 0.0 1219.0
TLS3_k127_5193626_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K01835,K01840 - 5.4.2.2,5.4.2.8 2.657e-247 774.0
TLS3_k127_5193626_2 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 494.0
TLS3_k127_5193626_3 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006285 267.0
TLS3_k127_5193626_4 Phytanoyl-CoA dioxygenase (PhyH) K00477,K18565 - 1.14.11.18 0.000000000000000000000000000000000000000000003239 174.0
TLS3_k127_5193626_5 transcriptional regulator (MarR - - - 0.0000000000000007425 87.0
TLS3_k127_5203501_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 547.0
TLS3_k127_5203501_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 298.0
TLS3_k127_5203501_2 Protein of unknown function (DUF3626) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008258 261.0
TLS3_k127_5203501_3 MDMPI C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000009491 240.0
TLS3_k127_5203501_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000005891 166.0
TLS3_k127_5203501_6 PFAM regulatory protein, MarR - - - 0.00000000000000000000000000001725 120.0
TLS3_k127_5203501_7 endonuclease activity - - - 0.00000000000003661 76.0
TLS3_k127_5219403_0 Histidine kinase K00936 - 2.7.13.3 7.881e-232 727.0
TLS3_k127_5219403_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 548.0
TLS3_k127_5219403_10 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K00441 - 1.12.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 285.0
TLS3_k127_5219403_11 Protein of unknown function (DUF3090) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001131 271.0
TLS3_k127_5219403_12 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000003891 251.0
TLS3_k127_5219403_13 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.00000000000000000000000000000000000000000000251 168.0
TLS3_k127_5219403_2 Electron transfer flavoprotein domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 528.0
TLS3_k127_5219403_3 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 505.0
TLS3_k127_5219403_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 497.0
TLS3_k127_5219403_5 alcohol dehydrogenase K13953,K18382 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 469.0
TLS3_k127_5219403_6 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 439.0
TLS3_k127_5219403_7 Phosphatidylinositol - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 370.0
TLS3_k127_5219403_8 Histidine phosphatase superfamily (branch 1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 362.0
TLS3_k127_5219403_9 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009041 344.0
TLS3_k127_5226411_0 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 372.0
TLS3_k127_5226411_1 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000002552 226.0
TLS3_k127_5226411_2 Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - - 0.0000000000000000000000000000000000000000000000000006326 190.0
TLS3_k127_5226411_3 lactoylglutathione lyase activity - - - 0.0000000003663 72.0
TLS3_k127_5226411_4 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000001201 57.0
TLS3_k127_5249779_0 Zn-dependent metallo-hydrolase RNA specificity domain K12574 - - 1.121e-310 960.0
TLS3_k127_5249779_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K14441 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 3.405e-218 688.0
TLS3_k127_5249779_10 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 312.0
TLS3_k127_5249779_11 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003613 277.0
TLS3_k127_5249779_12 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003272 268.0
TLS3_k127_5249779_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000001092 242.0
TLS3_k127_5249779_14 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000004594 210.0
TLS3_k127_5249779_15 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.0000000000000000000000000000000000000000000002278 174.0
TLS3_k127_5249779_2 Ftsk_gamma K03466 - - 3.61e-200 655.0
TLS3_k127_5249779_3 Competence-damaged protein K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 601.0
TLS3_k127_5249779_4 gluconolactonase activity K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 519.0
TLS3_k127_5249779_5 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 473.0
TLS3_k127_5249779_6 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 458.0
TLS3_k127_5249779_7 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 458.0
TLS3_k127_5249779_8 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 415.0
TLS3_k127_5249779_9 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 332.0
TLS3_k127_5259727_0 WD40-like Beta Propeller Repeat - - - 8.167e-319 998.0
TLS3_k127_5259727_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 1.712e-267 849.0
TLS3_k127_5259727_10 nuclease K01174,K07038 - 3.1.31.1 0.0000000000000000000000000000000000000000000000003722 180.0
TLS3_k127_5259727_11 positive regulation of acetylcholine metabolic process K06910 - - 0.000000000000000000000000000000000000000000000005399 185.0
TLS3_k127_5259727_12 protein conserved in bacteria K09781 - - 0.00000000000000000000000000000000000000000001088 164.0
TLS3_k127_5259727_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 1.286e-217 682.0
TLS3_k127_5259727_3 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 604.0
TLS3_k127_5259727_4 GlcNAc-PI de-N-acetylase K18455 - 3.5.1.115 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 489.0
TLS3_k127_5259727_5 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 446.0
TLS3_k127_5259727_6 NADH pyrophosphatase K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 380.0
TLS3_k127_5259727_7 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 323.0
TLS3_k127_5259727_8 Glucose-regulated metallo-peptidase M90 K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 317.0
TLS3_k127_5259727_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002336 228.0
TLS3_k127_5264486_0 Transport permease protein K09692 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 377.0
TLS3_k127_5264486_1 Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 348.0
TLS3_k127_5264486_2 ATPases associated with a variety of cellular activities K09693 - 3.6.3.40 0.0000000000000000000000000000000000000000000000000000000000000000008844 237.0
TLS3_k127_5264486_3 lipopolysaccharide metabolic process K08309,K19804 - - 0.00000000000000000000000000000001728 145.0
TLS3_k127_5264486_4 TIGRFAM conserved repeat domain - - - 0.00000000000002071 83.0
TLS3_k127_5272649_0 ABC1 family - - - 1.03e-255 795.0
TLS3_k127_5272649_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 9.46e-246 779.0
TLS3_k127_5272649_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003033 282.0
TLS3_k127_5272649_11 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005329 277.0
TLS3_k127_5272649_12 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002099 295.0
TLS3_k127_5272649_13 Inositol monophosphatase family K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004022 276.0
TLS3_k127_5272649_14 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000001277 261.0
TLS3_k127_5272649_15 Sterol carrier protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006445 246.0
TLS3_k127_5272649_17 Antibiotic biosynthesis monooxygenase K06996,K21481 - 1.14.99.57 0.00000000000000000000000000000000000000000000005974 175.0
TLS3_k127_5272649_18 zinc ion binding K06204 - - 0.000000002187 65.0
TLS3_k127_5272649_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008948 571.0
TLS3_k127_5272649_3 permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 552.0
TLS3_k127_5272649_4 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 482.0
TLS3_k127_5272649_5 phosphonate ABC transporter, inner membrane subunit K02042 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 494.0
TLS3_k127_5272649_6 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 392.0
TLS3_k127_5272649_8 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 329.0
TLS3_k127_5272649_9 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 329.0
TLS3_k127_5273018_0 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 437.0
TLS3_k127_5273018_1 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000005377 231.0
TLS3_k127_5273018_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000005275 54.0
TLS3_k127_5304524_0 B3/4 domain K01890 - 6.1.1.20 0.0 1225.0
TLS3_k127_5304524_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 4.416e-230 723.0
TLS3_k127_5304524_10 Uncharacterized protein conserved in bacteria (DUF2332) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 390.0
TLS3_k127_5304524_11 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 362.0
TLS3_k127_5304524_12 SpoU rRNA Methylase family K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 321.0
TLS3_k127_5304524_13 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 314.0
TLS3_k127_5304524_14 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 298.0
TLS3_k127_5304524_15 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 291.0
TLS3_k127_5304524_16 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001747 279.0
TLS3_k127_5304524_17 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003452 280.0
TLS3_k127_5304524_18 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003521 250.0
TLS3_k127_5304524_19 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000393 241.0
TLS3_k127_5304524_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 1.827e-199 645.0
TLS3_k127_5304524_20 Putative methyltransferase K00564 - 2.1.1.172 0.0000000000000000000000000000000000000000000000000000000003426 231.0
TLS3_k127_5304524_21 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000007811 203.0
TLS3_k127_5304524_22 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000000001161 193.0
TLS3_k127_5304524_23 acetyltransferase K03824 - - 0.000000000000000000000000000000000000000000000000000005079 197.0
TLS3_k127_5304524_24 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000001499 192.0
TLS3_k127_5304524_25 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000004444 199.0
TLS3_k127_5304524_26 - - - - 0.0000000000000000000000000000000000000005812 153.0
TLS3_k127_5304524_27 Transcriptional regulator, effector-binding domain component - - - 0.000000000000000000000000000000000001276 144.0
TLS3_k127_5304524_28 YCII-related domain - - - 0.0000000000000000000000000000000000129 141.0
TLS3_k127_5304524_29 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000005408 139.0
TLS3_k127_5304524_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 555.0
TLS3_k127_5304524_30 ACT domain K09964 - - 0.000000000000000000000000000000002188 134.0
TLS3_k127_5304524_31 enzyme binding K00567,K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 0.00000000000000000000000000000003461 134.0
TLS3_k127_5304524_32 - - - - 0.00000000000000000000000587 103.0
TLS3_k127_5304524_33 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000006548 91.0
TLS3_k127_5304524_35 Domain of unknown function (DUF4440) - - - 0.0000000000001777 79.0
TLS3_k127_5304524_36 - - - - 0.0000000000005094 74.0
TLS3_k127_5304524_37 - - - - 0.00000000000131 71.0
TLS3_k127_5304524_38 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000008465 70.0
TLS3_k127_5304524_39 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000001268 70.0
TLS3_k127_5304524_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 507.0
TLS3_k127_5304524_40 - - - - 0.000000001752 59.0
TLS3_k127_5304524_41 - - - - 0.0001325 51.0
TLS3_k127_5304524_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 497.0
TLS3_k127_5304524_6 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 482.0
TLS3_k127_5304524_7 Belongs to the sigma-70 factor family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 468.0
TLS3_k127_5304524_8 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 465.0
TLS3_k127_5304524_9 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004898 427.0
TLS3_k127_5311885_0 Glutamine amidotransferase domain K00820 - 2.6.1.16 0.0 1564.0
TLS3_k127_5311885_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1365.0
TLS3_k127_5311885_10 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 2.191e-217 686.0
TLS3_k127_5311885_11 Iron-sulfur cluster-binding domain - - - 2.512e-217 678.0
TLS3_k127_5311885_12 NADH:flavin oxidoreductase / NADH oxidase family - - - 3.346e-204 653.0
TLS3_k127_5311885_13 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090 - 2.547e-203 638.0
TLS3_k127_5311885_14 alcohol dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 625.0
TLS3_k127_5311885_15 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 578.0
TLS3_k127_5311885_16 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 518.0
TLS3_k127_5311885_17 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 511.0
TLS3_k127_5311885_18 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 495.0
TLS3_k127_5311885_19 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 498.0
TLS3_k127_5311885_2 Peptidase, M16 K07263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 4.71e-319 1004.0
TLS3_k127_5311885_20 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 474.0
TLS3_k127_5311885_21 Cell envelope-related transcriptional attenuator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 451.0
TLS3_k127_5311885_22 endonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 452.0
TLS3_k127_5311885_23 von Willebrand factor type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 451.0
TLS3_k127_5311885_24 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 419.0
TLS3_k127_5311885_25 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0008150,GO:0040007 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 406.0
TLS3_k127_5311885_26 PFAM ATPase associated with various cellular activities, AAA_5 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 408.0
TLS3_k127_5311885_27 tRNA threonylcarbamoyladenosine modification K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 391.0
TLS3_k127_5311885_28 Short-chain dehydrogenase reductase sdr K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 384.0
TLS3_k127_5311885_29 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 353.0
TLS3_k127_5311885_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.98e-309 953.0
TLS3_k127_5311885_30 NlpC/P60 family K21471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 362.0
TLS3_k127_5311885_31 PFAM Glycosyl transferases group 1 K03867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 356.0
TLS3_k127_5311885_32 Tetrapyrrole (Corrin/Porphyrin) Methylases K02303,K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 348.0
TLS3_k127_5311885_33 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 321.0
TLS3_k127_5311885_34 nUDIX hydrolase - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 302.0
TLS3_k127_5311885_36 PFAM Glycosyl transferase family 2 K00694 - 2.4.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002359 308.0
TLS3_k127_5311885_37 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000001085 280.0
TLS3_k127_5311885_38 carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002239 251.0
TLS3_k127_5311885_39 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003817 249.0
TLS3_k127_5311885_4 AMP-binding enzyme C-terminal domain - - - 2.634e-292 905.0
TLS3_k127_5311885_40 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000002393 244.0
TLS3_k127_5311885_41 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003164 241.0
TLS3_k127_5311885_42 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000000000000000000000000000000000000000117 234.0
TLS3_k127_5311885_43 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000000147 221.0
TLS3_k127_5311885_44 Ribosomal protein S9/S16 K02996 - - 0.00000000000000000000000000000000000000000000000000000004452 205.0
TLS3_k127_5311885_45 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000007829 181.0
TLS3_k127_5311885_46 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000000000001193 180.0
TLS3_k127_5311885_47 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000002607 164.0
TLS3_k127_5311885_49 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000002707 140.0
TLS3_k127_5311885_5 AAA domain - - - 1.213e-288 901.0
TLS3_k127_5311885_50 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 GO:0008150,GO:0040007 - 0.0000000000000000000007944 104.0
TLS3_k127_5311885_51 Elongator protein 3, MiaB family, Radical SAM - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000001771 91.0
TLS3_k127_5311885_6 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.645e-281 876.0
TLS3_k127_5311885_7 signal transduction protein containing a membrane domain an EAL and a GGDEF domain K21023 - 2.7.7.65 2.059e-275 869.0
TLS3_k127_5311885_8 Nitrite and sulphite reductase 4Fe-4S domain K00392 - 1.8.7.1 2.855e-273 854.0
TLS3_k127_5311885_9 synthetase K18688 - 6.2.1.42 6.024e-262 815.0
TLS3_k127_5313_0 Nonribosomal peptide synthetase - - - 0.0 1208.0
TLS3_k127_5313_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.0 1120.0
TLS3_k127_5313_10 TrkA-C domain K03499 - - 2.372e-200 633.0
TLS3_k127_5313_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 589.0
TLS3_k127_5313_12 Protein synonym peptidase M K01265 GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 575.0
TLS3_k127_5313_13 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 548.0
TLS3_k127_5313_14 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 529.0
TLS3_k127_5313_15 Cytochrome b/b6/petB K03891 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 503.0
TLS3_k127_5313_16 PFAM Fatty acid desaturase, type 2 K03921 - 1.14.19.11,1.14.19.2,1.14.19.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 499.0
TLS3_k127_5313_17 N-6 DNA Methylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 503.0
TLS3_k127_5313_18 (Pantothenic acid kinase)) K00867 GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 497.0
TLS3_k127_5313_19 Polyprenyl synthetase K00805 - 2.5.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 497.0
TLS3_k127_5313_2 protein synonym multiple resistance and pH homeostasis protein A K00341 - 1.6.5.3 1.565e-314 974.0
TLS3_k127_5313_20 FAD binding domain K21401 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016491,GO:0016627,GO:0030312,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 1.3.99.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 447.0
TLS3_k127_5313_21 Cytochrome b(C-terminal)/b6/petD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 424.0
TLS3_k127_5313_22 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 424.0
TLS3_k127_5313_23 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 422.0
TLS3_k127_5313_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 415.0
TLS3_k127_5313_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 375.0
TLS3_k127_5313_26 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 372.0
TLS3_k127_5313_27 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 358.0
TLS3_k127_5313_28 Belongs to the ATP-dependent AMP-binding enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 351.0
TLS3_k127_5313_29 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 331.0
TLS3_k127_5313_3 PFAM AMP-dependent synthetase and ligase K00666 - - 1.501e-278 866.0
TLS3_k127_5313_30 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 328.0
TLS3_k127_5313_31 Aminoglycoside/hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 345.0
TLS3_k127_5313_32 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 329.0
TLS3_k127_5313_33 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 299.0
TLS3_k127_5313_34 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004299 276.0
TLS3_k127_5313_35 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001306 265.0
TLS3_k127_5313_36 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001327 258.0
TLS3_k127_5313_37 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001227 236.0
TLS3_k127_5313_38 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000001297 219.0
TLS3_k127_5313_39 Putative ATP-dependant zinc protease - - - 0.0000000000000000000000000000000000000000000000000000000001257 208.0
TLS3_k127_5313_4 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 1.677e-259 805.0
TLS3_k127_5313_40 Macrocin-O-methyltransferase (TylF) - - - 0.00000000000000000000000000000000000000000000000000000001761 205.0
TLS3_k127_5313_41 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000002302 198.0
TLS3_k127_5313_42 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000000000000000000000002694 188.0
TLS3_k127_5313_43 dioxygenase activity K18056 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016706,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0046483,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:1901334,GO:1901336,GO:1901360,GO:1901362,GO:1901576 1.14.11.35 0.00000000000000000000000000000000000000000000000002163 192.0
TLS3_k127_5313_44 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.0000000000000000000000000000000000000000000000005416 202.0
TLS3_k127_5313_45 Mycolic acid cyclopropane synthetase K15942 - 2.1.1.288 0.0000000000000000000000000000000000000003019 163.0
TLS3_k127_5313_46 YbaK prolyl-tRNA synthetase associated region - - - 0.000000000000000000000000000000000003217 154.0
TLS3_k127_5313_47 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000003337 141.0
TLS3_k127_5313_48 Cytochrome c K02275 - 1.9.3.1 0.000000000000000000000000000008475 126.0
TLS3_k127_5313_49 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000001257 121.0
TLS3_k127_5313_5 Protein synonym NADH dehydrogenase I subunit M K00342 - 1.6.5.3 5.787e-255 821.0
TLS3_k127_5313_50 - - - - 0.000000000000000000000000000834 120.0
TLS3_k127_5313_51 Winged helix DNA-binding domain - - - 0.000000000000000000003398 97.0
TLS3_k127_5313_52 Mechanosensitive ion channel K22044 - - 0.00000000000000000003552 100.0
TLS3_k127_5313_53 A domain family that is part of the cupin metalloenzyme superfamily. - - - 0.00000000000000000006044 105.0
TLS3_k127_5313_54 HupE / UreJ protein - - - 0.000000000000000002317 100.0
TLS3_k127_5313_56 Histone methylation protein DOT1 - - - 0.0000000006981 71.0
TLS3_k127_5313_57 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.000001355 54.0
TLS3_k127_5313_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.774e-253 793.0
TLS3_k127_5313_7 Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA K03498 - - 5.52e-235 742.0
TLS3_k127_5313_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 3.617e-229 719.0
TLS3_k127_5313_9 Prokaryotic glutathione synthetase, ATP-grasp domain K05844 - - 1.863e-208 654.0
TLS3_k127_5370016_0 sugar transferase - - - 1.437e-205 671.0
TLS3_k127_5370016_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 523.0
TLS3_k127_5370016_10 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000001976 179.0
TLS3_k127_5370016_11 O-Antigen ligase - - - 0.00000000000000002455 95.0
TLS3_k127_5370016_2 Glycosyltransferase like family 2 K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 491.0
TLS3_k127_5370016_3 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 396.0
TLS3_k127_5370016_4 HhH-GPD superfamily base excision DNA repair protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 343.0
TLS3_k127_5370016_5 ATPases associated with a variety of cellular activities K01990,K09691,K09693 - 3.6.3.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 333.0
TLS3_k127_5370016_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 313.0
TLS3_k127_5370016_7 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000007275 222.0
TLS3_k127_5370016_8 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000008659 214.0
TLS3_k127_5370016_9 Glycosyl transferase, family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000002763 196.0
TLS3_k127_5388968_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1379.0
TLS3_k127_5388968_1 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 6.493e-252 786.0
TLS3_k127_5388968_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 443.0
TLS3_k127_5388968_11 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 411.0
TLS3_k127_5388968_12 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005252 383.0
TLS3_k127_5388968_13 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 325.0
TLS3_k127_5388968_14 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 327.0
TLS3_k127_5388968_15 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 312.0
TLS3_k127_5388968_16 Cytidylate kinase K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 301.0
TLS3_k127_5388968_17 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 297.0
TLS3_k127_5388968_18 Phosphoglycerate mutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001486 275.0
TLS3_k127_5388968_19 Protein of unknown function (DUF3151) - - - 0.000000000000000000000000000000000000000000000000000000000000000000004223 236.0
TLS3_k127_5388968_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 5.545e-220 686.0
TLS3_k127_5388968_20 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000000000000000000000000001845 228.0
TLS3_k127_5388968_21 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000108 235.0
TLS3_k127_5388968_22 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000000001326 217.0
TLS3_k127_5388968_23 Heat shock protein DnaJ domain protein K05516 - - 0.0000000000000000000000000000000000000000000162 171.0
TLS3_k127_5388968_24 molybdenum cofactor guanylyltransferase activity K03637,K03752,K13818 - 2.7.7.77,4.6.1.17 0.00000000000000000000000000000000000119 145.0
TLS3_k127_5388968_25 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.00000000000000000000000000000000000171 149.0
TLS3_k127_5388968_27 Rhodanese Homology Domain - - - 0.000000000000000000000000000001107 127.0
TLS3_k127_5388968_28 HIT domain K02503 - - 0.0000000000000000000000000008584 113.0
TLS3_k127_5388968_29 AAA domain - - - 0.00000000000000000000000001289 118.0
TLS3_k127_5388968_3 M18 family aminopeptidase K01267 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.21 8.641e-198 628.0
TLS3_k127_5388968_30 Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.00000000000000000000000004073 114.0
TLS3_k127_5388968_31 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000005341 112.0
TLS3_k127_5388968_33 - - - - 0.0000007645 51.0
TLS3_k127_5388968_4 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 606.0
TLS3_k127_5388968_5 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 595.0
TLS3_k127_5388968_6 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 567.0
TLS3_k127_5388968_7 3-dehydroquinate synthase K16020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 478.0
TLS3_k127_5388968_8 xylulose kinase K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 460.0
TLS3_k127_5388968_9 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 453.0
TLS3_k127_5410697_0 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000000000000000000000000009107 199.0
TLS3_k127_5410697_1 lipid-transfer protein - - - 0.00000000000000000000000000000000000000000000000000003935 196.0
TLS3_k127_5410697_2 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.00000000000000000000000000000000000000000000000000004825 191.0
TLS3_k127_5410697_3 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.000000001409 69.0
TLS3_k127_5498402_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0 1184.0
TLS3_k127_5498402_1 Cell division protein FtsA K03569 - - 7.525e-206 651.0
TLS3_k127_5498402_2 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 5.948e-203 639.0
TLS3_k127_5498402_3 Cell cycle protein K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 612.0
TLS3_k127_5498402_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 584.0
TLS3_k127_5498402_5 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 340.0
TLS3_k127_5498402_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000005111 258.0
TLS3_k127_5498402_7 - K03571 - - 0.000000000000000000000000000000000000000000000000000000002312 212.0
TLS3_k127_5588431_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008323 396.0
TLS3_k127_5588431_1 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 333.0
TLS3_k127_5588431_2 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 347.0
TLS3_k127_5588431_3 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003018 243.0
TLS3_k127_5588431_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000001473 217.0
TLS3_k127_5588431_5 glyoxalase bleomycin resistance protein dioxygenase - GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 - 0.000000000000000000000000000000000000000000000000000003656 195.0
TLS3_k127_5610880_0 Sigma factor PP2C-like phosphatases K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009398 470.0
TLS3_k127_5610880_1 Protein of unknown function (DUF2662) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 321.0
TLS3_k127_5610880_2 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000005633 221.0
TLS3_k127_5626929_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1033.0
TLS3_k127_5626929_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 1.93e-198 625.0
TLS3_k127_5626929_10 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000267 126.0
TLS3_k127_5626929_2 CoA-transferase family III K07749,K18313 - 2.8.3.16,2.8.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 552.0
TLS3_k127_5626929_3 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 512.0
TLS3_k127_5626929_4 Anion-transporting ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 416.0
TLS3_k127_5626929_5 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 374.0
TLS3_k127_5626929_6 COG0530 Ca2 Na antiporter K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 329.0
TLS3_k127_5626929_7 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 299.0
TLS3_k127_5626929_8 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002044 252.0
TLS3_k127_5626929_9 transcriptional - - - 0.000000000000000000000000000000000000127 152.0
TLS3_k127_5641900_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0 1007.0
TLS3_k127_5641900_1 Dehydratase family K01687 - 4.2.1.9 8.328e-306 968.0
TLS3_k127_5641900_10 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 284.0
TLS3_k127_5641900_11 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004917 280.0
TLS3_k127_5641900_12 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000009722 219.0
TLS3_k127_5641900_13 regulatory, ligand-binding protein related to C-terminal domains of K channels K07228 - - 0.0000000000000000000000000000000000000000000000000000000002082 209.0
TLS3_k127_5641900_14 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000000000000000000000000000002011 196.0
TLS3_k127_5641900_15 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.000000000000000000000000000000000000006229 151.0
TLS3_k127_5641900_16 YhhN family - - - 0.000000000000000000000000000000000001593 146.0
TLS3_k127_5641900_17 Protein of unknown function (DUF3054) - - - 0.000000000000000000000000000008112 123.0
TLS3_k127_5641900_18 Domain of unknown function (DUF4234) - - - 0.000000000000000000000000001082 123.0
TLS3_k127_5641900_2 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.235e-261 814.0
TLS3_k127_5641900_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 573.0
TLS3_k127_5641900_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 567.0
TLS3_k127_5641900_5 Pfam Sodium hydrogen exchanger K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000936 506.0
TLS3_k127_5641900_6 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006298 458.0
TLS3_k127_5641900_7 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 376.0
TLS3_k127_5641900_8 DNA-binding transcription factor activity K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 329.0
TLS3_k127_5641900_9 ACT domain K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 296.0
TLS3_k127_5644448_0 Glycine cleavage system P-protein K00281,K00283 - 1.4.4.2 0.0 1493.0
TLS3_k127_5644448_1 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0 1108.0
TLS3_k127_5644448_10 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 432.0
TLS3_k127_5644448_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 432.0
TLS3_k127_5644448_12 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 406.0
TLS3_k127_5644448_13 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 373.0
TLS3_k127_5644448_14 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 352.0
TLS3_k127_5644448_15 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 343.0
TLS3_k127_5644448_16 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 345.0
TLS3_k127_5644448_17 SOS response associated peptidase (SRAP) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 332.0
TLS3_k127_5644448_18 Belongs to the UPF0271 (lamB) family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 323.0
TLS3_k127_5644448_19 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009384 313.0
TLS3_k127_5644448_2 Proteasomal ATPase OB/ID domain K13527 - - 1.248e-307 956.0
TLS3_k127_5644448_20 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 300.0
TLS3_k127_5644448_21 allophanate hydrolase subunit 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009599 319.0
TLS3_k127_5644448_22 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 290.0
TLS3_k127_5644448_23 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000265 288.0
TLS3_k127_5644448_24 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009012 273.0
TLS3_k127_5644448_25 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001893 271.0
TLS3_k127_5644448_26 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006056 249.0
TLS3_k127_5644448_27 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.00000000000000000000000000000000000000000000000000000000000000000000001649 247.0
TLS3_k127_5644448_28 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000001489 226.0
TLS3_k127_5644448_29 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000007409 235.0
TLS3_k127_5644448_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 8.862e-297 915.0
TLS3_k127_5644448_31 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000005909 205.0
TLS3_k127_5644448_32 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.0000000000000000000000000000000000000000000000000000001097 215.0
TLS3_k127_5644448_33 Histidine triad (Hit) protein K02503 - - 0.00000000000000000000000000000000000000000000000000002339 190.0
TLS3_k127_5644448_34 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000004198 188.0
TLS3_k127_5644448_35 phosphatase activity K05967 - - 0.000000000000000000000000000000000000000000000000005794 199.0
TLS3_k127_5644448_37 - - - - 0.000000000000000000000000000000000000000000001163 170.0
TLS3_k127_5644448_38 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000000000000000000000000000000000000008057 163.0
TLS3_k127_5644448_39 lipid kinase activity - - - 0.00000000000000000000000000000000000000000003764 168.0
TLS3_k127_5644448_4 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 - 6.3.1.19 2.749e-284 874.0
TLS3_k127_5644448_41 transcriptional regulator - - - 0.00000000000000000000000000000000007298 154.0
TLS3_k127_5644448_42 ABC transporter (Permease K02042 - - 0.000000000000000000000000000000002198 139.0
TLS3_k127_5644448_43 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000002992 139.0
TLS3_k127_5644448_44 protein secretion K03116,K03117 GO:0003674,GO:0005215 - 0.00000000000000000000000000000006064 128.0
TLS3_k127_5644448_45 cyclic nucleotide binding - - - 0.0000000000000000000000000000001117 131.0
TLS3_k127_5644448_46 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000053 119.0
TLS3_k127_5644448_47 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation K13570 - - 0.0000000000000000000003454 98.0
TLS3_k127_5644448_49 helix_turn_helix, Lux Regulon - - - 0.00000000001525 69.0
TLS3_k127_5644448_5 Pup-ligase protein K20814 - 3.5.1.119 4.165e-280 865.0
TLS3_k127_5644448_50 - - - - 0.00000006972 62.0
TLS3_k127_5644448_6 DSHCT K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 1.794e-215 709.0
TLS3_k127_5644448_7 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 509.0
TLS3_k127_5644448_8 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 501.0
TLS3_k127_5644448_9 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 504.0
TLS3_k127_5665081_0 extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 501.0
TLS3_k127_5665081_1 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) - - - 0.00000000000000000000000000000003632 136.0
TLS3_k127_5665081_2 Prokaryotic N-terminal methylation motif - - - 0.0000000000000168 84.0
TLS3_k127_5665081_3 - - - - 0.000000000001629 78.0
TLS3_k127_5665081_4 - - - - 0.000000000008741 69.0
TLS3_k127_5701561_0 Pfam Sulfatase K01130 - 3.1.6.1 0.0 1230.0
TLS3_k127_5701561_1 Peroxidase K03782 - 1.11.1.21 0.0 1198.0
TLS3_k127_5701561_10 protein some members contain a von Willebrand factor type A vWA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 417.0
TLS3_k127_5701561_11 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 386.0
TLS3_k127_5701561_12 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 387.0
TLS3_k127_5701561_13 sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007963 372.0
TLS3_k127_5701561_14 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 358.0
TLS3_k127_5701561_15 iron ion homeostasis K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 343.0
TLS3_k127_5701561_16 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 334.0
TLS3_k127_5701561_17 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 318.0
TLS3_k127_5701561_18 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 312.0
TLS3_k127_5701561_19 Phosphorylase superfamily K01243 - 3.2.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000002961 256.0
TLS3_k127_5701561_2 Oligopeptide dipeptide ABC transporter domain protein K02031,K02032 - - 2.121e-223 709.0
TLS3_k127_5701561_20 DNA repair protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003357 244.0
TLS3_k127_5701561_21 acyl-CoA hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000006912 237.0
TLS3_k127_5701561_22 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000006168 225.0
TLS3_k127_5701561_23 LURP-one-related - - - 0.0000000000000000000000000000000000000000000000000000000002502 207.0
TLS3_k127_5701561_24 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000025 200.0
TLS3_k127_5701561_25 Ferric uptake regulator family K22297 - - 0.000000000000000000000000000000000000000000000000000002584 194.0
TLS3_k127_5701561_26 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000002524 205.0
TLS3_k127_5701561_27 Bacterial PH domain - - - 0.00000000000000000000000000000000000000000000000006826 185.0
TLS3_k127_5701561_28 Domain of unknown function (DUF4129) - - - 0.0000000000000000000000000000000000000000000005351 177.0
TLS3_k127_5701561_29 Belongs to the carbohydrate kinase PfkB family - - - 0.00000000000000000000000000000000000000000001763 179.0
TLS3_k127_5701561_3 Flavin-binding monooxygenase-like - - - 8.07e-203 645.0
TLS3_k127_5701561_30 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000004296 102.0
TLS3_k127_5701561_32 Dodecin K09165 - - 0.000000000001248 79.0
TLS3_k127_5701561_33 - - - - 0.000002118 58.0
TLS3_k127_5701561_4 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 558.0
TLS3_k127_5701561_5 Binding-protein-dependent transport systems inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 558.0
TLS3_k127_5701561_6 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 530.0
TLS3_k127_5701561_7 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 510.0
TLS3_k127_5701561_8 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 490.0
TLS3_k127_5701561_9 Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons K01563 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 479.0
TLS3_k127_5765463_0 - - - - 0.00000000000000000000000000000000000000000000000009981 186.0
TLS3_k127_5765463_1 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000007922 158.0
TLS3_k127_5765463_2 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000003673 156.0
TLS3_k127_5765463_3 Inner membrane component domain - - - 0.000000000000000000000000000000002358 132.0
TLS3_k127_5765463_4 dTDP-4-dehydrorhamnose reductase K00067 - 1.1.1.133 0.00000000000000272 81.0
TLS3_k127_5772222_0 alcohol dehydrogenase K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 317.0
TLS3_k127_5772222_1 Regulatory protein tetr - - - 0.00000000000000000000000000000000000000000000002081 177.0
TLS3_k127_5785031_0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006075 276.0
TLS3_k127_5785031_1 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000006582 267.0
TLS3_k127_5785031_2 Cytidylyltransferase K00983 - 2.7.7.43 0.000000000000000000000000000000000000000000000000000000000000000001602 245.0
TLS3_k127_5785031_3 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000000001772 210.0
TLS3_k127_5785031_4 RmlD substrate binding domain - - - 0.0000000000000002491 93.0
TLS3_k127_5789649_0 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 342.0
TLS3_k127_5845010_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 5.775e-282 880.0
TLS3_k127_5845010_1 Peptidase dimerisation domain - - - 2.63e-245 764.0
TLS3_k127_5845010_10 nuclease K01174 - 3.1.31.1 0.0000000000000000000005946 101.0
TLS3_k127_5845010_11 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000002162 77.0
TLS3_k127_5845010_12 Domain of unknown function (DUF222) - - - 0.000003682 48.0
TLS3_k127_5845010_2 DEAD-like helicases superfamily - - - 1.28e-214 683.0
TLS3_k127_5845010_3 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 389.0
TLS3_k127_5845010_4 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 360.0
TLS3_k127_5845010_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001326 244.0
TLS3_k127_5845010_6 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000008617 222.0
TLS3_k127_5845010_7 uridine kinase - - - 0.00000000000000000000000000000000000000003335 161.0
TLS3_k127_5845010_8 YGGT family - - - 0.00000000000000000000000001812 118.0
TLS3_k127_5845010_9 Divergent 4Fe-4S mono-cluster K05337 - - 0.00000000000000000000000264 115.0
TLS3_k127_5869617_0 Molydopterin dinucleotide binding domain K00122 - 1.17.1.9 7.01e-292 915.0
TLS3_k127_5869617_1 virion core protein, lumpy skin disease virus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 580.0
TLS3_k127_5869617_10 PFAM Activator of Hsp90 ATPase 1 family protein - - - 0.00000000000000000000000000000000000000000352 164.0
TLS3_k127_5869617_11 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000001158 151.0
TLS3_k127_5869617_12 belongs to the sigma-70 factor family K03090 GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000000000001999 151.0
TLS3_k127_5869617_13 arsR family - - - 0.000000000000000000000000000000000002631 142.0
TLS3_k127_5869617_14 PFAM helix-turn-helix HxlR type - - - 0.00000000000000000000000000001205 127.0
TLS3_k127_5869617_15 - - - - 0.000000000000000000001685 98.0
TLS3_k127_5869617_16 Conserved protein domain typically associated with flavoprotein oxygenases DIM6 NTAB family - - - 0.0000000000002489 71.0
TLS3_k127_5869617_17 AefR-like transcriptional repressor, C-terminal region - - - 0.0001499 45.0
TLS3_k127_5869617_2 bacterial-type flagellum-dependent swarming motility - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 520.0
TLS3_k127_5869617_3 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 449.0
TLS3_k127_5869617_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 400.0
TLS3_k127_5869617_5 taurine catabolism dioxygenase K22303 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016705,GO:0016706,GO:0051213,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 329.0
TLS3_k127_5869617_6 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001983 266.0
TLS3_k127_5869617_7 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000002494 233.0
TLS3_k127_5869617_8 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000002212 217.0
TLS3_k127_5869617_9 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000002439 164.0
TLS3_k127_5891725_0 Transglutaminase/protease-like homologues - - - 6.283e-224 725.0
TLS3_k127_5891725_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 443.0
TLS3_k127_5891725_2 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 401.0
TLS3_k127_5891725_3 Protein of unknown function (DUF3040) - - - 0.000000000000000000000000000000000000000000369 162.0
TLS3_k127_5891725_4 ROK family K00845 - 2.7.1.2 0.00000002806 58.0
TLS3_k127_5986149_0 DEAD-like helicases superfamily K03724,K06877 - - 0.0 1480.0
TLS3_k127_5986149_1 dTDP-4-dehydrorhamnose reductase K00067 - 1.1.1.133 0.00000000000000000000000007224 118.0
TLS3_k127_5997207_0 Uncharacterised protein family (UPF0182) K09118 - - 0.0 1266.0
TLS3_k127_5997207_1 ABC transporter transmembrane region K06147,K06148 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 398.0
TLS3_k127_5997207_2 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 333.0
TLS3_k127_5997207_3 regulation of cell shape K04074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 307.0
TLS3_k127_5997207_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007031 289.0
TLS3_k127_5997207_5 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001357 253.0
TLS3_k127_5997207_6 nuclear chromosome segregation K19765 - - 0.00000000000000002139 96.0
TLS3_k127_6026721_0 cAMP biosynthetic process K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000007313 229.0
TLS3_k127_6026721_1 SMART HNH nuclease - - - 0.0000000000000000000000000000000000000000000000000000005291 195.0
TLS3_k127_6026721_2 pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000000000000000005434 186.0
TLS3_k127_6047104_0 MDMPI C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002884 261.0
TLS3_k127_6047104_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003216 265.0
TLS3_k127_6047104_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003483 246.0
TLS3_k127_6047104_3 - - - - 0.0000000000000000000000004377 114.0
TLS3_k127_6047104_4 Pkd domain containing protein - - - 0.0000003791 59.0
TLS3_k127_6066599_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1165.0
TLS3_k127_6066599_1 Flavoprotein involved in K transport - - - 1.169e-228 723.0
TLS3_k127_6066599_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007898 405.0
TLS3_k127_6066599_11 PFAM SMP-30 Gluconolaconase K13874,K14274 - 3.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 347.0
TLS3_k127_6066599_12 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 334.0
TLS3_k127_6066599_13 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 322.0
TLS3_k127_6066599_14 inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 316.0
TLS3_k127_6066599_15 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 310.0
TLS3_k127_6066599_16 Bacterial extracellular solute-binding protein K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005009 279.0
TLS3_k127_6066599_17 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007599 274.0
TLS3_k127_6066599_18 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004285 272.0
TLS3_k127_6066599_19 glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008568 264.0
TLS3_k127_6066599_2 Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine K18912 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0055114,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.14.99.50 3.167e-194 627.0
TLS3_k127_6066599_20 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000008198 236.0
TLS3_k127_6066599_21 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000003741 205.0
TLS3_k127_6066599_22 DoxX K15977 - - 0.00000000000000000000000000000000000000000000000004036 185.0
TLS3_k127_6066599_23 - - - - 0.000000000000000000000000000000000000000000000001268 195.0
TLS3_k127_6066599_24 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000001089 155.0
TLS3_k127_6066599_25 Predicted metal-dependent hydrolase K07044 - - 0.000000000000000000000000000004007 139.0
TLS3_k127_6066599_26 Methyltransferase domain - - - 0.00000000000000000000000002499 112.0
TLS3_k127_6066599_27 PFAM AIG2 family protein - - - 0.0000000000000000000000000581 121.0
TLS3_k127_6066599_28 dehydrogenases and related proteins - - - 0.00000000000000000002663 103.0
TLS3_k127_6066599_29 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K00657,K06718,K18816 - 2.3.1.178,2.3.1.57,2.3.1.82 0.000000000000000536 83.0
TLS3_k127_6066599_3 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 588.0
TLS3_k127_6066599_30 COG2335 Secreted and surface protein containing fasciclin-like repeats K19519 - - 0.00000005275 62.0
TLS3_k127_6066599_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 508.0
TLS3_k127_6066599_5 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 481.0
TLS3_k127_6066599_6 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 479.0
TLS3_k127_6066599_7 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 416.0
TLS3_k127_6066599_8 F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 429.0
TLS3_k127_6066599_9 Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine K18911 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008213,GO:0008276,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0019439,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0036211,GO:0042398,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052707,GO:0052708,GO:0052709,GO:0052803,GO:0052805,GO:0071704,GO:0071944,GO:0097164,GO:0140096,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 407.0
TLS3_k127_6072779_0 - - - - 6.268e-203 637.0
TLS3_k127_6072779_1 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 557.0
TLS3_k127_6072779_10 Belongs to the binding-protein-dependent transport system permease family K01997,K11956 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 325.0
TLS3_k127_6072779_11 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 321.0
TLS3_k127_6072779_12 xylulose kinase K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000288 233.0
TLS3_k127_6072779_13 5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000002242 186.0
TLS3_k127_6072779_14 lipolytic protein G-D-S-L family - - - 0.00000000000000000000003059 114.0
TLS3_k127_6072779_15 - - - - 0.000000000000005155 88.0
TLS3_k127_6072779_16 N-acetylmuramoyl-L-alanine amidase - - - 0.0002124 53.0
TLS3_k127_6072779_2 Enoyl-CoA hydratase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007654 438.0
TLS3_k127_6072779_3 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 443.0
TLS3_k127_6072779_4 Short-chain dehydrogenase reductase sdr K00046,K00059 - 1.1.1.100,1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 396.0
TLS3_k127_6072779_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 379.0
TLS3_k127_6072779_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 375.0
TLS3_k127_6072779_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 351.0
TLS3_k127_6072779_8 Cytochrome oxidase assembly protein K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007733 352.0
TLS3_k127_6072779_9 alpha-ribazole phosphatase activity K02226,K15634 - 3.1.3.73,5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 346.0
TLS3_k127_6078727_0 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0 1266.0
TLS3_k127_6078727_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0 1086.0
TLS3_k127_6078727_10 L-valine transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000321 209.0
TLS3_k127_6078727_11 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000006641 187.0
TLS3_k127_6078727_12 Pfam Pyridoxamine 5'-phosphate - GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0030312,GO:0031406,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0070967,GO:0071944,GO:0097159,GO:0097367,GO:1901363 - 0.0000000000000000000000000000000000000000000000002819 187.0
TLS3_k127_6078727_13 - - - - 0.0000000000000000000000000000000004064 136.0
TLS3_k127_6078727_14 Branched-chain amino acid transport protein (AzlD) - - - 0.000000000000001464 85.0
TLS3_k127_6078727_2 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 569.0
TLS3_k127_6078727_3 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 527.0
TLS3_k127_6078727_4 Glycosylase K05522 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 469.0
TLS3_k127_6078727_5 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 457.0
TLS3_k127_6078727_6 C-terminal domain of 1-Cys peroxiredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 406.0
TLS3_k127_6078727_7 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 404.0
TLS3_k127_6078727_8 ADP-ribose pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 320.0
TLS3_k127_6078727_9 cytidyltransferase-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003997 238.0
TLS3_k127_6092085_0 PFAM glycoside hydrolase, family 10 - - - 7.564e-214 671.0
TLS3_k127_6092085_1 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 593.0
TLS3_k127_6092085_10 Domain of unknown function (DUF3817) - - - 0.000000000000000000000003506 115.0
TLS3_k127_6092085_11 membrane K09790 - - 0.0000000000000000007038 98.0
TLS3_k127_6092085_12 FG-GAP repeat - - - 0.00000001438 70.0
TLS3_k127_6092085_2 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 554.0
TLS3_k127_6092085_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 371.0
TLS3_k127_6092085_4 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000004857 229.0
TLS3_k127_6092085_5 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000000000000002201 209.0
TLS3_k127_6092085_6 pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000000000000000007135 195.0
TLS3_k127_6092085_7 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000001067 128.0
TLS3_k127_6092085_8 SnoaL-like domain - - - 0.000000000000000000000000008933 115.0
TLS3_k127_6092085_9 Belongs to the peptidase S8 family - - - 0.0000000000000000000000005258 125.0
TLS3_k127_6103090_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 533.0
TLS3_k127_6103090_1 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 370.0
TLS3_k127_6112753_0 Protein synonym hydantoin utilization protein A K01473 - 3.5.2.14 0.0 1063.0
TLS3_k127_6112753_1 Protein synonym hydantoin utilization protein B K01474 - 3.5.2.14 3.043e-272 880.0
TLS3_k127_6112753_10 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 382.0
TLS3_k127_6112753_11 endonuclease activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 394.0
TLS3_k127_6112753_12 drug resistance transporter, EmrB QacA subfamily - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 381.0
TLS3_k127_6112753_13 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 355.0
TLS3_k127_6112753_14 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 353.0
TLS3_k127_6112753_15 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 310.0
TLS3_k127_6112753_16 Belongs to the glycosyl hydrolase 68 family K00692,K01193 GO:0005575,GO:0005576 2.4.1.10,3.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 302.0
TLS3_k127_6112753_17 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008415 316.0
TLS3_k127_6112753_18 Activator of hsp90 atpase 1 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001456 261.0
TLS3_k127_6112753_19 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002997 278.0
TLS3_k127_6112753_2 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 4.427e-253 788.0
TLS3_k127_6112753_20 Activator of Hsp90 ATPase 1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001419 253.0
TLS3_k127_6112753_21 Transcriptional regulator K05799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001668 252.0
TLS3_k127_6112753_22 efflux transmembrane transporter activity K02004 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009405,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0051704,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000004593 253.0
TLS3_k127_6112753_23 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000001342 239.0
TLS3_k127_6112753_24 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000001096 230.0
TLS3_k127_6112753_25 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.0000000000000000000000000000000000000000000000000000000000000004288 235.0
TLS3_k127_6112753_26 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000003944 209.0
TLS3_k127_6112753_27 PFAM CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000000000000000000000000000001125 209.0
TLS3_k127_6112753_28 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000007649 202.0
TLS3_k127_6112753_29 transmembrane transport K01992 - - 0.0000000000000000000000000000000000000000000000000000002591 215.0
TLS3_k127_6112753_3 Rieske 2Fe-2S K00479 - - 6.11e-215 672.0
TLS3_k127_6112753_30 Cupin domain - - - 0.000000000000000000000000000000000000000000000000001043 203.0
TLS3_k127_6112753_31 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000006504 184.0
TLS3_k127_6112753_32 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000008805 176.0
TLS3_k127_6112753_33 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000001972 192.0
TLS3_k127_6112753_34 - - - - 0.00000000000000000000000000000000000000003264 158.0
TLS3_k127_6112753_35 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000002686 153.0
TLS3_k127_6112753_36 Pfam Methyltransferase - - - 0.0000000000000000000000000000000001123 147.0
TLS3_k127_6112753_37 Calx-beta domain - - - 0.0000000000000000000000000000000295 148.0
TLS3_k127_6112753_38 YjbR - - - 0.0000000000000000000000000000003128 137.0
TLS3_k127_6112753_39 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000048 140.0
TLS3_k127_6112753_4 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 596.0
TLS3_k127_6112753_40 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.00000000000000000000000000005172 124.0
TLS3_k127_6112753_41 Abortive infection protein K07052 - - 0.00000000000000000000000000008754 125.0
TLS3_k127_6112753_42 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000001031 124.0
TLS3_k127_6112753_43 - - - - 0.000000000000000000000002803 115.0
TLS3_k127_6112753_44 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000003198 88.0
TLS3_k127_6112753_45 domain protein K21688 GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016 - 0.00000000000006514 83.0
TLS3_k127_6112753_46 - - - - 0.0001164 46.0
TLS3_k127_6112753_5 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 584.0
TLS3_k127_6112753_6 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 518.0
TLS3_k127_6112753_7 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 501.0
TLS3_k127_6112753_8 Glycosyl hydrolase family 32 K01193 - 3.2.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 498.0
TLS3_k127_6112753_9 Alpha/beta-hydrolase family N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 446.0
TLS3_k127_6121576_0 protein secretion K20276,K21449 - - 0.0 1613.0
TLS3_k127_6121576_1 4Fe-4S dicluster domain - - - 0.0 1352.0
TLS3_k127_6121576_10 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700,K01236 - 2.4.1.18,3.2.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007802 530.0
TLS3_k127_6121576_11 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 492.0
TLS3_k127_6121576_12 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 484.0
TLS3_k127_6121576_13 DNA segregation ATPase FtsK SpoIIIE and related K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 512.0
TLS3_k127_6121576_14 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 489.0
TLS3_k127_6121576_15 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 378.0
TLS3_k127_6121576_16 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 359.0
TLS3_k127_6121576_17 Chalcone and stilbene synthases, C-terminal domain K16167 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 362.0
TLS3_k127_6121576_18 transmembrane transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 309.0
TLS3_k127_6121576_19 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 305.0
TLS3_k127_6121576_2 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 0.0 1128.0
TLS3_k127_6121576_20 zinc finger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004462 261.0
TLS3_k127_6121576_21 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000003367 275.0
TLS3_k127_6121576_22 SNF2 family N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004518 251.0
TLS3_k127_6121576_24 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000000003926 237.0
TLS3_k127_6121576_25 MgtC family K07507 - - 0.0000000000000000000000000000000000000000000000000000000000000008088 226.0
TLS3_k127_6121576_26 helix_turn_helix, mercury resistance K13640 - - 0.000000000000000000000000000000000000000000000000000000001455 203.0
TLS3_k127_6121576_27 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000007842 180.0
TLS3_k127_6121576_28 Membrane - - - 0.0000000000000000000000000000000000000000000000001146 188.0
TLS3_k127_6121576_29 Isoprenylcysteine carboxyl methyltransferase K16168 - - 0.0000000000000000000000000000000000000000006797 163.0
TLS3_k127_6121576_3 Heat shock 70 kDa protein K04043 - - 0.0 1086.0
TLS3_k127_6121576_30 PFAM CMP dCMP deaminase zinc-binding K01489 - 3.5.4.5 0.00000000000000000000000000000000000000001991 159.0
TLS3_k127_6121576_31 Transcriptional regulator, MarR family - - - 0.0000000000000000000000000000000000000002484 163.0
TLS3_k127_6121576_32 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000002854 137.0
TLS3_k127_6121576_33 cyclic nucleotide binding K10914 - - 0.00000000000000000000000005158 115.0
TLS3_k127_6121576_4 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 9.683e-314 976.0
TLS3_k127_6121576_5 metallocarboxypeptidase activity - - - 1.139e-260 815.0
TLS3_k127_6121576_6 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 7.109e-253 822.0
TLS3_k127_6121576_7 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 1.047e-208 669.0
TLS3_k127_6121576_8 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 523.0
TLS3_k127_6121576_9 metal ion transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 541.0
TLS3_k127_6125081_0 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.0 1069.0
TLS3_k127_6125081_1 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 420.0
TLS3_k127_6125081_2 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008404 415.0
TLS3_k127_6125081_3 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 402.0
TLS3_k127_6125081_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 349.0
TLS3_k127_6125081_5 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 348.0
TLS3_k127_6125081_6 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 310.0
TLS3_k127_6125081_7 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 312.0
TLS3_k127_6125081_9 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000006358 112.0
TLS3_k127_6134386_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1297.0
TLS3_k127_6134386_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1264.0
TLS3_k127_6134386_10 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000001081 143.0
TLS3_k127_6134386_11 Nucleic-acid-binding protein implicated in transcription termination K02600,K07742 - - 0.0000000000000000000007405 98.0
TLS3_k127_6134386_2 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009554 458.0
TLS3_k127_6134386_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 370.0
TLS3_k127_6134386_4 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 353.0
TLS3_k127_6134386_5 DSBA oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 305.0
TLS3_k127_6134386_6 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000359 248.0
TLS3_k127_6134386_7 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000007817 214.0
TLS3_k127_6134386_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000000000000006817 182.0
TLS3_k127_6134386_9 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000000000000000004238 175.0
TLS3_k127_6140501_0 Protein synonym acyl-CoA synthetase K01897 - 6.2.1.3 1.38e-295 912.0
TLS3_k127_6140501_1 Protein of unknown function (DUF512) - - - 2.299e-245 764.0
TLS3_k127_6140501_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 2.666e-219 688.0
TLS3_k127_6140501_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 2.738e-218 696.0
TLS3_k127_6140501_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 579.0
TLS3_k127_6140501_5 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000461 256.0
TLS3_k127_6140501_6 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000001458 239.0
TLS3_k127_6140501_8 Domain of unknown function (DUF222) - - - 0.0000000001759 63.0
TLS3_k127_6148220_0 Protein kinase domain K12132 - 2.7.11.1 2.69e-277 870.0
TLS3_k127_6148220_1 Cell cycle protein - - - 5.434e-237 741.0
TLS3_k127_6148220_10 DSBA oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002572 255.0
TLS3_k127_6148220_11 glyoxalase bleomycin resistance protein dioxygenase K06991 - - 0.000000000000000000000000000000000000000000000000000000000000000002682 234.0
TLS3_k127_6148220_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000005244 236.0
TLS3_k127_6148220_13 DNA-binding transcription factor activity K18996 - - 0.00000000000000000000000000000000000000000000000000000001386 201.0
TLS3_k127_6148220_14 CGNR zinc finger - - - 0.0000000000000000000000000000000000000000000000000000002776 199.0
TLS3_k127_6148220_15 - - - - 0.000000000000000000000000000000000000000000000000000001025 199.0
TLS3_k127_6148220_16 thiolester hydrolase activity K17362 - - 0.00000000000000000000000000000000000000000000000000008672 190.0
TLS3_k127_6148220_17 - - - - 0.00000000000000000000000000000000000000000001593 162.0
TLS3_k127_6148220_19 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000002146 97.0
TLS3_k127_6148220_2 Penicillin binding protein transpeptidase domain K05364 - - 1.271e-223 704.0
TLS3_k127_6148220_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 2.57e-199 627.0
TLS3_k127_6148220_4 Reductase C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 560.0
TLS3_k127_6148220_5 ABC transporter transmembrane region K06147,K06148 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006824 413.0
TLS3_k127_6148220_6 ABC transporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 352.0
TLS3_k127_6148220_7 Peptidase C26 K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006886 332.0
TLS3_k127_6148220_8 SpoU rRNA Methylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 335.0
TLS3_k127_6148220_9 Inosine-uridine preferring nucleoside hydrolase K01239 - 3.2.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 296.0
TLS3_k127_6155192_0 RecF/RecN/SMC N terminal domain K03529 - - 0.0 1616.0
TLS3_k127_6155192_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1133.0
TLS3_k127_6155192_10 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 367.0
TLS3_k127_6155192_11 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 302.0
TLS3_k127_6155192_12 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003406 283.0
TLS3_k127_6155192_13 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000000000000000004559 241.0
TLS3_k127_6155192_14 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000000000001626 218.0
TLS3_k127_6155192_15 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000000000000000000002463 222.0
TLS3_k127_6155192_16 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000003517 210.0
TLS3_k127_6155192_17 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000000000000009969 179.0
TLS3_k127_6155192_18 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000297 182.0
TLS3_k127_6155192_19 Ribosomal protein S16 K02959 - - 0.0000000000000000000000000000000000000006014 149.0
TLS3_k127_6155192_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1095.0
TLS3_k127_6155192_20 Ribosomal L27 protein K02899 - - 0.0000000000000000000000000000000004524 132.0
TLS3_k127_6155192_21 nuclease activity K07460 - - 0.000000000000000000000000000000001144 134.0
TLS3_k127_6155192_22 Belongs to the UPF0109 family K06960 GO:0008150,GO:0040007 - 0.000000000000000000000000000000004387 133.0
TLS3_k127_6155192_23 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000003703 128.0
TLS3_k127_6155192_24 Cold shock K03704 - - 0.000000000000000000000000000008944 120.0
TLS3_k127_6155192_25 Ribosomal L28 family K02902 - - 0.0000000000000000000000000002071 133.0
TLS3_k127_6155192_26 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000000000007925 108.0
TLS3_k127_6155192_27 Alkyl sulfatase dimerisation - - - 0.0001006 46.0
TLS3_k127_6155192_3 Dak1_2 K07030 - - 1.505e-257 806.0
TLS3_k127_6155192_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 2.483e-253 788.0
TLS3_k127_6155192_5 Acyl-CoA dehydrogenase, N-terminal domain - - - 1.466e-221 692.0
TLS3_k127_6155192_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 512.0
TLS3_k127_6155192_7 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 480.0
TLS3_k127_6155192_8 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 432.0
TLS3_k127_6155192_9 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 400.0
TLS3_k127_6159065_0 dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 577.0
TLS3_k127_6159065_1 Peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 344.0
TLS3_k127_6159065_2 PFAM Inositol monophosphatase K01092,K05602 - 3.1.3.15,3.1.3.25 0.00000000000000000000000000000000000000002133 162.0
TLS3_k127_6159065_3 - - - - 0.00000000000000000000000000000000655 136.0
TLS3_k127_6159065_4 alcohol dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000002253 109.0
TLS3_k127_6159065_6 Protein of unknown function (DUF1360) - - - 0.0006809 48.0
TLS3_k127_6202673_0 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 321.0
TLS3_k127_6202673_1 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 314.0
TLS3_k127_6202673_10 Transcriptional regulator - - - 0.00000000000000009801 90.0
TLS3_k127_6202673_11 InterPro IPR014922 - - - 0.00000000000182 72.0
TLS3_k127_6202673_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001798 272.0
TLS3_k127_6202673_3 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000005885 224.0
TLS3_k127_6202673_4 DeoR C terminal sensor domain - - - 0.00000000000000000000000000000000000000000000000000000000001577 214.0
TLS3_k127_6202673_5 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000004962 213.0
TLS3_k127_6202673_6 isomerase activity K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000006914 185.0
TLS3_k127_6202673_7 AefR-like transcriptional repressor, C-terminal region - - - 0.0000000000000000000000000000000000000000000007772 185.0
TLS3_k127_6202673_8 Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P K00845 - 2.7.1.2 0.00000000000000000000000000000000000007324 154.0
TLS3_k127_6202673_9 Histidine kinase K02484 - 2.7.13.3 0.000000000000000000000000000006971 122.0
TLS3_k127_6222655_0 indolepyruvate ferredoxin oxidoreductase K00179,K04090 - 1.2.7.8 0.0 1152.0
TLS3_k127_6222655_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 4.551e-280 886.0
TLS3_k127_6222655_10 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008004 527.0
TLS3_k127_6222655_11 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009843 535.0
TLS3_k127_6222655_12 peptidase K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 507.0
TLS3_k127_6222655_13 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 474.0
TLS3_k127_6222655_14 neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 482.0
TLS3_k127_6222655_15 Helix-turn-helix domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 460.0
TLS3_k127_6222655_16 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 438.0
TLS3_k127_6222655_17 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 426.0
TLS3_k127_6222655_18 WYL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 421.0
TLS3_k127_6222655_19 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 422.0
TLS3_k127_6222655_2 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 7.568e-280 866.0
TLS3_k127_6222655_20 RarD protein K05786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 402.0
TLS3_k127_6222655_21 transcriptional regulator K13573 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 406.0
TLS3_k127_6222655_22 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 404.0
TLS3_k127_6222655_23 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 391.0
TLS3_k127_6222655_24 Peptidoglycan-binding domain 1 protein K01227,K01448,K03791,K13277,K17733 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016787,GO:0017171,GO:0018104,GO:0019538,GO:0030203,GO:0030312,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.2.1.96,3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 379.0
TLS3_k127_6222655_25 ROK family K00845,K00886 - 2.7.1.2,2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 364.0
TLS3_k127_6222655_26 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 372.0
TLS3_k127_6222655_27 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 335.0
TLS3_k127_6222655_28 K -dependent Na Ca exchanger K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 324.0
TLS3_k127_6222655_29 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001051 265.0
TLS3_k127_6222655_3 Flavin-binding monooxygenase-like K03379,K18091 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0044237,GO:0044249,GO:0046483,GO:0055114,GO:0071704,GO:1901334,GO:1901336,GO:1901360,GO:1901362,GO:1901576 1.14.13.170,1.14.13.171,1.14.13.22 4.314e-271 846.0
TLS3_k127_6222655_30 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000004921 239.0
TLS3_k127_6222655_31 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000008562 239.0
TLS3_k127_6222655_32 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000002488 223.0
TLS3_k127_6222655_33 - - - - 0.0000000000000000000000000000000000000000000000000000000009464 212.0
TLS3_k127_6222655_34 Phosphoglucose isomerase K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000222 207.0
TLS3_k127_6222655_35 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000513 201.0
TLS3_k127_6222655_36 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000001455 192.0
TLS3_k127_6222655_37 Phospholipase_D-nuclease N-terminal - - - 0.000000000000000000000000000000000000000000005605 167.0
TLS3_k127_6222655_38 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.000000000000000000000000000000000000000009607 157.0
TLS3_k127_6222655_39 Domain of unknown function (DUF202) K00389 - - 0.000000000000000000000000000000000001876 145.0
TLS3_k127_6222655_4 Phosphoglucose isomerase K01810 - 5.3.1.9 1.76e-257 809.0
TLS3_k127_6222655_40 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000002498 132.0
TLS3_k127_6222655_41 Transglycosylase associated protein - - - 0.000000000000000000000000000008331 121.0
TLS3_k127_6222655_43 AMP binding - - - 0.000000000000000000000001041 109.0
TLS3_k127_6222655_44 Phosphate acyltransferases - - - 0.00000000000000000000002827 116.0
TLS3_k127_6222655_45 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000001932 110.0
TLS3_k127_6222655_46 DJ-1 PfpI family - - - 0.00000000000000000005033 99.0
TLS3_k127_6222655_48 Stress responsive A/B Barrel Domain - - - 0.000000000000000002264 91.0
TLS3_k127_6222655_5 Belongs to the argininosuccinate synthase family. Type K01940 - 6.3.4.5 2.051e-256 803.0
TLS3_k127_6222655_50 Ceramidase - - - 0.000000007122 69.0
TLS3_k127_6222655_51 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006355,GO:0006725,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010106,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019725,GO:0030003,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0040007,GO:0042262,GO:0042592,GO:0042594,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046916,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0060255,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090143,GO:0090304,GO:0097100,GO:0097159,GO:0098771,GO:0140110,GO:1901360,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000001599 55.0
TLS3_k127_6222655_6 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 6.016e-233 728.0
TLS3_k127_6222655_7 acyl-CoA dehydrogenase activity - - - 1.008e-220 692.0
TLS3_k127_6222655_8 ABC-type branched-chain amino acid transport - - - 1.579e-206 652.0
TLS3_k127_6222655_9 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 529.0
TLS3_k127_6244412_0 ABC transporter transmembrane region K06147 - - 7.637e-309 955.0
TLS3_k127_6244412_1 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 572.0
TLS3_k127_6244412_2 5'-3' exonuclease, C-terminal SAM fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 459.0
TLS3_k127_6244412_3 Phage-related minor tail protein K15771,K18642,K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008577 288.0
TLS3_k127_6244412_4 signal recognition particle binding K06398,K06945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000022 281.0
TLS3_k127_6244412_5 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000001229 206.0
TLS3_k127_6244412_7 Roadblock/LC7 domain K07131 - - 0.00000000000000000000000000000008915 130.0
TLS3_k127_6262380_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 556.0
TLS3_k127_6262380_1 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001093 290.0
TLS3_k127_6262380_2 transcriptional regulator - - - 0.0000000000000000000000000000000001513 152.0
TLS3_k127_6264925_0 Protein of unknown function (DUF1254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 434.0
TLS3_k127_6264925_1 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000000000000000000000000000000006871 241.0
TLS3_k127_6264925_2 Domain of unknown function (DUF222) - - - 0.00000000000000000000000000000000000000000000000004317 192.0
TLS3_k127_6271121_0 AAA domain - - - 0.0 1023.0
TLS3_k127_6271121_1 type III restriction enzyme, res subunit - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 2.708e-262 820.0
TLS3_k127_6271121_2 iron dependent repressor K03709 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 377.0
TLS3_k127_6271121_3 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000882 304.0
TLS3_k127_6274979_0 arsenical-resistance protein K03325,K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005894 527.0
TLS3_k127_6274979_1 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001314 257.0
TLS3_k127_6274979_10 helix_turn_helix, Lux Regulon - - - 0.000000000000000006466 91.0
TLS3_k127_6274979_11 Protein of unknown function (DUF3618) - - - 0.000000000000000008094 93.0
TLS3_k127_6274979_12 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0000000000000359 81.0
TLS3_k127_6274979_13 NAD binding domain of 6-phosphogluconate dehydrogenase - - - 0.00001748 50.0
TLS3_k127_6274979_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000001265 207.0
TLS3_k127_6274979_3 RNA polymerase sigma factor, sigma-70 family K03090 - - 0.000000000000000000000000000000000000000000000001527 183.0
TLS3_k127_6274979_4 Predicted membrane protein (DUF2243) - - - 0.0000000000000000000000000000000000000000001219 169.0
TLS3_k127_6274979_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000001224 165.0
TLS3_k127_6274979_6 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000001005 151.0
TLS3_k127_6274979_7 Histidine kinase - - - 0.0000000000000000000000000000000004774 150.0
TLS3_k127_6274979_8 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000000000000000000000007606 115.0
TLS3_k127_6274979_9 DNA-binding transcription factor activity - - - 0.0000000000000000000001611 112.0
TLS3_k127_6281445_0 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0 1063.0
TLS3_k127_6281445_1 Major facilitator Superfamily - - - 4.187e-254 793.0
TLS3_k127_6281445_10 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 457.0
TLS3_k127_6281445_11 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 437.0
TLS3_k127_6281445_12 endonuclease activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 409.0
TLS3_k127_6281445_13 Predicted membrane protein (DUF2254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 403.0
TLS3_k127_6281445_14 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 354.0
TLS3_k127_6281445_15 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 347.0
TLS3_k127_6281445_16 belongs to the sigma-70 factor family K03090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 313.0
TLS3_k127_6281445_17 - K07395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 306.0
TLS3_k127_6281445_18 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001938 275.0
TLS3_k127_6281445_19 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009947 264.0
TLS3_k127_6281445_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.549e-253 791.0
TLS3_k127_6281445_20 translation release factor activity K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001211 271.0
TLS3_k127_6281445_21 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000001128 257.0
TLS3_k127_6281445_22 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000006745 233.0
TLS3_k127_6281445_23 FR47-like protein - - - 0.000000000000000000000000000000000000000000000000000005344 197.0
TLS3_k127_6281445_24 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000002876 195.0
TLS3_k127_6281445_25 Molybdopterin oxidoreductase K00123 - 1.17.1.9 0.0000000000000000000000000005043 119.0
TLS3_k127_6281445_26 - - - - 0.000000000000000000000000574 118.0
TLS3_k127_6281445_28 Transcriptional regulator K10914 - - 0.0000000000000006346 86.0
TLS3_k127_6281445_29 - - - - 0.0000000000003568 70.0
TLS3_k127_6281445_3 Sulfatase - - - 1.398e-233 735.0
TLS3_k127_6281445_30 STAS domain K04749 - - 0.0000006745 57.0
TLS3_k127_6281445_32 Anti-sigma regulatory factor (Ser Thr protein kinase) - - - 0.0002773 49.0
TLS3_k127_6281445_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00122,K00335 - 1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 625.0
TLS3_k127_6281445_5 Oligopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 560.0
TLS3_k127_6281445_6 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 499.0
TLS3_k127_6281445_7 endonuclease activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 480.0
TLS3_k127_6281445_8 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 470.0
TLS3_k127_6281445_9 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 463.0
TLS3_k127_6306006_0 Dihydropyrimidinase K01464 - 3.5.2.2 8.272e-252 784.0
TLS3_k127_6306006_1 Carbon-nitrogen hydrolase K01431 - 3.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 321.0
TLS3_k127_6306006_2 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.000000000000000008526 83.0
TLS3_k127_6354274_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 360.0
TLS3_k127_6354274_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 355.0
TLS3_k127_6354274_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000008076 235.0
TLS3_k127_6354274_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000000002225 226.0
TLS3_k127_6354274_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000003173 203.0
TLS3_k127_6354274_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000006007 184.0
TLS3_k127_6354859_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1465.0
TLS3_k127_6354859_1 Deoxyribodipyrimidine photo-lyase-related protein K06876 - - 8.956e-247 770.0
TLS3_k127_6354859_10 ATPases associated with a variety of cellular activities K05780 - 2.7.8.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 316.0
TLS3_k127_6354859_11 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 299.0
TLS3_k127_6354859_12 Phytanoyl-CoA dioxygenase (PhyH) K21195 - 1.14.11.46 0.000000000000000000000000000000000000000000000000000000000000000000000000003471 272.0
TLS3_k127_6354859_13 organic phosphonate catabolic process K05781,K06163 GO:0005575,GO:0006793,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0019634,GO:0019637,GO:0019700,GO:0032991,GO:0044237,GO:0046434,GO:0071704,GO:1901575,GO:1902494,GO:1904176 4.7.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003663 268.0
TLS3_k127_6354859_14 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000006067 227.0
TLS3_k127_6354859_15 - - - - 0.00000000000000000000000000000000000000000004486 170.0
TLS3_k127_6354859_16 Phytanoyl-CoA dioxygenase (PhyH) K21195 - 1.14.11.46 0.0000000000000000000000000000000000000000001342 173.0
TLS3_k127_6354859_17 Protein of unknown function (DUF952) K00799,K01560,K21420 - 2.3.2.29,2.5.1.18,3.8.1.2 0.000000000000000000000000000000000000000001266 160.0
TLS3_k127_6354859_18 Type II secretion system (T2SS), protein F K12511 - - 0.00000000000000000000000000000000001191 151.0
TLS3_k127_6354859_19 Type ii secretion system K12510 - - 0.000000000000000000000000000000675 132.0
TLS3_k127_6354859_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 548.0
TLS3_k127_6354859_20 PFAM TadE family protein - - - 0.000000000000000000000000000001433 133.0
TLS3_k127_6354859_21 Phosphonate metabolism protein PhnG K06166 - 2.7.8.37 0.000000000000000000000000000485 118.0
TLS3_k127_6354859_22 - - - - 0.00000000000000000000000001813 111.0
TLS3_k127_6354859_23 UTRA K02043 - - 0.0000000000000000000008409 106.0
TLS3_k127_6354859_25 Bacterial phosphonate metabolism protein (PhnH) K06165 - 2.7.8.37 0.000000005781 66.0
TLS3_k127_6354859_26 Belongs to the anti-sigma-factor antagonist family K04749 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00006825 53.0
TLS3_k127_6354859_27 2Fe-2S -binding domain K02192 - - 0.00007035 49.0
TLS3_k127_6354859_3 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 451.0
TLS3_k127_6354859_4 Bacterial phosphonate metabolism protein (PhnI) K06164 - 2.7.8.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 445.0
TLS3_k127_6354859_5 replication factor c K02341,K02343,K09384 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 422.0
TLS3_k127_6354859_6 type II secretion system protein E K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 414.0
TLS3_k127_6354859_7 Phosphonate metabolism protein PhnJ K06163 - 4.7.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 384.0
TLS3_k127_6354859_8 Phosphonate metabolism K06162 - 3.6.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008892 372.0
TLS3_k127_6354859_9 Phosphonate K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 322.0
TLS3_k127_6412495_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1129.0
TLS3_k127_6412495_1 von Willebrand factor (vWF) type A domain - - - 0.0 1119.0
TLS3_k127_6412495_10 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.00000000000000000000000000000000000000007289 157.0
TLS3_k127_6412495_11 protein secretion K03116 - - 0.00000000004185 66.0
TLS3_k127_6412495_2 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 0.0 1000.0
TLS3_k127_6412495_3 beta-mannosidase K01192,K15855 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0071704,GO:1901575 3.2.1.165,3.2.1.25 2.98e-304 947.0
TLS3_k127_6412495_4 Mg-chelatase subunit ChlI K03405 - 6.6.1.1 5.472e-256 794.0
TLS3_k127_6412495_5 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 464.0
TLS3_k127_6412495_6 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 319.0
TLS3_k127_6412495_7 beta-glucosidase activity K00067,K05350 - 1.1.1.133,3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002368 280.0
TLS3_k127_6412495_8 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000000000000000000000000000000000000000000000000000008006 199.0
TLS3_k127_6412495_9 - - - - 0.00000000000000000000000000000000000000007155 153.0
TLS3_k127_645243_0 endonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 417.0
TLS3_k127_645243_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 376.0
TLS3_k127_645243_2 - - - - 0.0000000000000000000000000000000000000000000000000003308 201.0
TLS3_k127_645243_3 PFAM peptidase S51 dipeptidase E K05995 - 3.4.13.21 0.000000000000000000000000000000000001454 139.0
TLS3_k127_645243_4 Protein of unknown function (DUF1622) - - - 0.000000000000000000000000553 110.0
TLS3_k127_645243_5 Transcriptional regulator - - - 0.000000000000000000255 90.0
TLS3_k127_6466657_0 DEAD-like helicases superfamily K03724,K06877 - - 2.847e-239 746.0
TLS3_k127_6466657_1 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 368.0
TLS3_k127_6466657_2 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 324.0
TLS3_k127_6466657_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 302.0
TLS3_k127_6466657_4 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 296.0
TLS3_k127_6466657_6 CcmB protein K02194 - - 0.00001202 57.0
TLS3_k127_6494365_0 DegT/DnrJ/EryC1/StrS aminotransferase family K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 590.0
TLS3_k127_6494365_1 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 587.0
TLS3_k127_6494365_10 Acetyltransferase (GNAT) family K06977 - - 0.000000000000000000000000000000000000000000003611 169.0
TLS3_k127_6494365_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 456.0
TLS3_k127_6494365_3 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 450.0
TLS3_k127_6494365_4 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 370.0
TLS3_k127_6494365_5 diguanylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 328.0
TLS3_k127_6494365_6 transport, permease protein K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 329.0
TLS3_k127_6494365_7 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 310.0
TLS3_k127_6494365_8 transport, permease protein K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 295.0
TLS3_k127_6494365_9 LysM domain K12204 - - 0.0000000000000000000000000000000000000000000000000000000004575 222.0
TLS3_k127_651046_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 482.0
TLS3_k127_651046_1 PhoD-like phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000832 454.0
TLS3_k127_651046_2 Domain present in PSD-95, Dlg, and ZO-1/2. K08372 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 418.0
TLS3_k127_651046_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 353.0
TLS3_k127_651046_4 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000000000000002298 206.0
TLS3_k127_651046_5 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000004376 213.0
TLS3_k127_6523844_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1084.0
TLS3_k127_6523844_1 Ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.0 1062.0
TLS3_k127_6523844_10 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 553.0
TLS3_k127_6523844_11 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 545.0
TLS3_k127_6523844_12 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 486.0
TLS3_k127_6523844_13 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 494.0
TLS3_k127_6523844_14 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 475.0
TLS3_k127_6523844_15 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 410.0
TLS3_k127_6523844_16 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 394.0
TLS3_k127_6523844_17 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 391.0
TLS3_k127_6523844_18 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 376.0
TLS3_k127_6523844_19 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 376.0
TLS3_k127_6523844_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 2.386e-254 789.0
TLS3_k127_6523844_20 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 344.0
TLS3_k127_6523844_21 Thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 338.0
TLS3_k127_6523844_22 N-formylglutamate amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 341.0
TLS3_k127_6523844_23 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 318.0
TLS3_k127_6523844_24 Protein of unknown function (DUF2889) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 322.0
TLS3_k127_6523844_25 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 301.0
TLS3_k127_6523844_26 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 296.0
TLS3_k127_6523844_27 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 300.0
TLS3_k127_6523844_28 Haemolysin-III related K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 284.0
TLS3_k127_6523844_29 triphosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000155 285.0
TLS3_k127_6523844_3 Class-II DAHP synthetase family K01626 - 2.5.1.54 2.833e-249 773.0
TLS3_k127_6523844_30 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002855 280.0
TLS3_k127_6523844_31 precorrin-8X methylmutase activity K06042 - 5.4.99.60,5.4.99.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001013 284.0
TLS3_k127_6523844_32 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003865 277.0
TLS3_k127_6523844_34 NAD(P)H dehydrogenase (quinone) activity K00355 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000004599 254.0
TLS3_k127_6523844_35 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003988 239.0
TLS3_k127_6523844_37 NAD(P)H dehydrogenase (quinone) activity K00355 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000007283 233.0
TLS3_k127_6523844_38 - - - - 0.0000000000000000000000000000000000000000000000000000000000005277 229.0
TLS3_k127_6523844_39 Phosphoglycerate mutase family K02226 GO:0003674,GO:0003824,GO:0003993,GO:0005488,GO:0005515,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0042802,GO:0042803,GO:0044237,GO:0046983 3.1.3.73 0.00000000000000000000000000000000000000000000000000008917 205.0
TLS3_k127_6523844_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 9.789e-223 698.0
TLS3_k127_6523844_40 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000000000000006905 194.0
TLS3_k127_6523844_41 Protein of unknown function (DUF983) - - - 0.0000000000000000000000000000000000000000000005179 169.0
TLS3_k127_6523844_42 TOBE domain K10111 - - 0.0000000000000000000000000000000000000000000006494 185.0
TLS3_k127_6523844_44 Chorismate mutase K04092 - 5.4.99.5 0.000000000000000000000000000000000000000000008018 165.0
TLS3_k127_6523844_45 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000002678 156.0
TLS3_k127_6523844_46 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000001128 152.0
TLS3_k127_6523844_47 - - - - 0.000000000000000000000000000001089 138.0
TLS3_k127_6523844_5 Cytochrome P450 K20497 - 1.14.15.14 1.659e-220 691.0
TLS3_k127_6523844_50 ROK family K00845 - 2.7.1.2 0.00000000000000001333 93.0
TLS3_k127_6523844_51 LysM domain - - - 0.00000000000000001592 88.0
TLS3_k127_6523844_52 DNA integration - - - 0.00003149 46.0
TLS3_k127_6523844_53 - - - - 0.0003983 51.0
TLS3_k127_6523844_6 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 615.0
TLS3_k127_6523844_7 Ferredoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 597.0
TLS3_k127_6523844_8 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 584.0
TLS3_k127_6523844_9 Anaerobic c4-dicarboxylate membrane transporter K07792 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 557.0
TLS3_k127_6573476_0 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 406.0
TLS3_k127_6573476_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000689 179.0
TLS3_k127_6573476_2 Flavin-nucleotide-binding protein K07005 - - 0.000000000000000000000000000000000002232 143.0
TLS3_k127_6573476_3 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.00000000000000000000000000000008222 130.0
TLS3_k127_6573476_4 Putative stress-induced transcription regulator - - - 0.000000000000000000000000000001697 130.0
TLS3_k127_6573476_5 Domain of unknown function (DUF1330) - - - 0.00000000000000000005741 103.0
TLS3_k127_6573476_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000007154 69.0
TLS3_k127_6638179_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 3.411e-228 718.0
TLS3_k127_6638179_1 MgsA AAA+ ATPase C terminal K07478 - - 7.829e-224 702.0
TLS3_k127_6638179_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 305.0
TLS3_k127_6638179_3 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 300.0
TLS3_k127_6638179_4 nUDIX hydrolase K08311 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0033554,GO:0034353,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0043487,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0045935,GO:0046483,GO:0046700,GO:0046872,GO:0048518,GO:0048519,GO:0048522,GO:0050779,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000001406 207.0
TLS3_k127_6638179_7 - - - - 0.000001425 55.0
TLS3_k127_6656488_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 568.0
TLS3_k127_6656488_1 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 351.0
TLS3_k127_6656488_3 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000000000002145 126.0
TLS3_k127_6666506_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 1.581e-267 829.0
TLS3_k127_6666506_1 PFAM HNH endonuclease - - - 0.000000003965 63.0
TLS3_k127_6703846_0 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 9.594e-252 786.0
TLS3_k127_6703846_1 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 1.897e-245 766.0
TLS3_k127_6703846_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 384.0
TLS3_k127_6703846_11 peptidase activity K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 376.0
TLS3_k127_6703846_12 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 364.0
TLS3_k127_6703846_13 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 327.0
TLS3_k127_6703846_14 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009962 259.0
TLS3_k127_6703846_15 Guanylyl transferase CofC like K14941 - 2.7.7.68 0.00000000000000000000000000000000000000000000000000000000000000000003988 239.0
TLS3_k127_6703846_16 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000000000000000000000000000000000000000000000002938 207.0
TLS3_k127_6703846_18 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K18917 - 1.20.4.3 0.00000000000000000000000000000000000007302 145.0
TLS3_k127_6703846_19 Transcriptional regulator - - - 0.000000000002279 72.0
TLS3_k127_6703846_2 Creatinase/Prolidase N-terminal domain - - - 2.459e-194 612.0
TLS3_k127_6703846_20 - - - - 0.0000007423 62.0
TLS3_k127_6703846_3 Cys/Met metabolism PLP-dependent enzyme K01739 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 510.0
TLS3_k127_6703846_4 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 486.0
TLS3_k127_6703846_5 DNA polymerase LigD polymerase domain K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 501.0
TLS3_k127_6703846_6 F420-dependent oxidoreductase K04091 - 1.14.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 454.0
TLS3_k127_6703846_7 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 424.0
TLS3_k127_6703846_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 415.0
TLS3_k127_6730167_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 315.0
TLS3_k127_6907049_0 N-acyl-D-aspartate D-glutamate deacylase - - - 2.35e-276 861.0
TLS3_k127_6907049_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.356e-243 757.0
TLS3_k127_6907049_10 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000201 240.0
TLS3_k127_6907049_11 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000002418 239.0
TLS3_k127_6907049_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000000000000002304 228.0
TLS3_k127_6907049_13 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000000000000002083 192.0
TLS3_k127_6907049_14 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000008989 171.0
TLS3_k127_6907049_15 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000000001554 143.0
TLS3_k127_6907049_16 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000001352 126.0
TLS3_k127_6907049_17 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001252 116.0
TLS3_k127_6907049_18 ThiS family - - - 0.0000000000000000000000000002476 117.0
TLS3_k127_6907049_19 Ribosomal protein L30p/L7e K02907 - - 0.0000000000000000000002201 106.0
TLS3_k127_6907049_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 492.0
TLS3_k127_6907049_3 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 440.0
TLS3_k127_6907049_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 379.0
TLS3_k127_6907049_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 324.0
TLS3_k127_6907049_6 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009056 312.0
TLS3_k127_6907049_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 290.0
TLS3_k127_6907049_8 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006027 260.0
TLS3_k127_6907049_9 binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009558 248.0
TLS3_k127_690842_0 Alpha-1,2-mannosidase - - - 0.0 1131.0
TLS3_k127_690842_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 571.0
TLS3_k127_690842_2 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 463.0
TLS3_k127_690842_3 metallocarboxypeptidase activity K14054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 310.0
TLS3_k127_690842_4 protein conserved in bacteria K09966 - - 0.0000000000000000000000000000000000000000000000000000000000002433 218.0
TLS3_k127_690842_5 VIT family - - - 0.00000000000000000000000000000000000000000000000001213 193.0
TLS3_k127_690842_6 Nitroreductase - - - 0.00000000000000000000000000000000000002046 144.0
TLS3_k127_6938845_0 PFAM Glycoside hydrolase, family 38 - - - 3.243e-317 1017.0
TLS3_k127_6938845_1 Binding-protein-dependent transport systems inner membrane component - - - 5.892e-250 790.0
TLS3_k127_6938845_10 Rieske 2Fe-2S - - - 0.000000000000000000000000000000000000000000000000000000000000002706 246.0
TLS3_k127_6938845_11 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000000000000000000001183 214.0
TLS3_k127_6938845_12 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000000000000000004587 201.0
TLS3_k127_6938845_13 Putative zinc-finger - - - 0.00000000000000000000000000000000000000000000000005075 187.0
TLS3_k127_6938845_14 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K18983 - 5.5.1.27 0.00000000000000000000000000000000000000000000009558 187.0
TLS3_k127_6938845_15 dioxygenase activity K00477,K21195 - 1.14.11.18,1.14.11.46 0.000000000000000000000000000000000000000000004732 173.0
TLS3_k127_6938845_16 Universal stress protein family - - - 0.00000000000000000000000000000000000000000003875 173.0
TLS3_k127_6938845_17 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor - - - 0.000000000000000000000000000006807 126.0
TLS3_k127_6938845_18 Cupin domain - - - 0.0000000000000000000192 103.0
TLS3_k127_6938845_2 NMT1/THI5 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 596.0
TLS3_k127_6938845_3 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 517.0
TLS3_k127_6938845_4 PFAM ring hydroxylating dioxygenase, alpha subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008772 500.0
TLS3_k127_6938845_5 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 434.0
TLS3_k127_6938845_6 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 342.0
TLS3_k127_6938845_7 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001851 264.0
TLS3_k127_6938845_8 CHRD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007563 262.0
TLS3_k127_6938845_9 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000001032 239.0
TLS3_k127_6948310_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 386.0
TLS3_k127_6948310_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000005632 149.0
TLS3_k127_6963166_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 GO:0008150,GO:0040007 3.5.1.5 0.0 1014.0
TLS3_k127_6963166_1 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 1.845e-229 719.0
TLS3_k127_6963166_10 Rieske 2Fe-2S - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 418.0
TLS3_k127_6963166_11 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 413.0
TLS3_k127_6963166_12 o-methyltransferase K21377 - 2.1.1.302 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 411.0
TLS3_k127_6963166_13 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 362.0
TLS3_k127_6963166_14 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 341.0
TLS3_k127_6963166_15 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 323.0
TLS3_k127_6963166_16 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 313.0
TLS3_k127_6963166_17 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 286.0
TLS3_k127_6963166_18 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003352 266.0
TLS3_k127_6963166_19 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003872 251.0
TLS3_k127_6963166_2 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 3.219e-220 693.0
TLS3_k127_6963166_20 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000001071 247.0
TLS3_k127_6963166_21 Urease, gamma subunit K01430 - 3.5.1.5 0.000000000000000000000000000000000000000000000000000000000000000000002138 249.0
TLS3_k127_6963166_22 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002831 227.0
TLS3_k127_6963166_23 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000001792 220.0
TLS3_k127_6963166_24 nickel cation binding K03190 - - 0.00000000000000000000000000000000000000000000000000000000127 209.0
TLS3_k127_6963166_25 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.000000000000000000000000000000000000000000000000000005218 203.0
TLS3_k127_6963166_26 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000001591 192.0
TLS3_k127_6963166_27 Domain of unknown function (DUF1905) - - - 0.00000000000000000000000000000001863 132.0
TLS3_k127_6963166_28 SnoaL-like polyketide cyclase - - - 0.00000000000000000000002361 114.0
TLS3_k127_6963166_29 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000007267 94.0
TLS3_k127_6963166_3 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 3.585e-208 655.0
TLS3_k127_6963166_30 metallocarboxypeptidase activity K14054 - - 0.00000000001826 76.0
TLS3_k127_6963166_4 Acetamidase/Formamidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 575.0
TLS3_k127_6963166_5 mandelate racemase muconate lactonizing K18983 - 5.5.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 518.0
TLS3_k127_6963166_6 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 509.0
TLS3_k127_6963166_7 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 481.0
TLS3_k127_6963166_8 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 466.0
TLS3_k127_6963166_9 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 460.0
TLS3_k127_7049560_0 bifunctional deaminase-reductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001383 238.0
TLS3_k127_7049560_1 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000000000000000000002012 209.0
TLS3_k127_7049560_2 AefR-like transcriptional repressor, C-terminal region - - - 0.000000000000000000000000000000000000000000000001755 182.0
TLS3_k127_7049560_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.00000000000000000000000000000000000000000002328 166.0
TLS3_k127_7049560_4 COG1525 Micrococcal nuclease (thermonuclease) homologs K01174 - 3.1.31.1 0.00000000000000000000000000000000000119 145.0
TLS3_k127_7049560_5 Histidine phosphatase superfamily (branch 1) K15634 - 5.4.2.12 0.0000000000000000000000767 101.0
TLS3_k127_7102042_0 transcriptional regulator - - - 1.316e-299 940.0
TLS3_k127_7102042_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 6.73e-218 685.0
TLS3_k127_7102042_2 Ecdysteroid kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008668 405.0
TLS3_k127_7102042_3 GlcNAc-PI de-N-acetylase K22135 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 344.0
TLS3_k127_7102042_4 WHG domain - - - 0.0000000000000000000000000000000000000000000000008367 183.0
TLS3_k127_7102042_5 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000158 160.0
TLS3_k127_7102042_6 Transcriptional regulator - - - 0.000000000000000000000000000000000000001009 154.0
TLS3_k127_7102042_7 PFAM chorismate K01665,K03342 - 2.6.1.85,4.1.3.38 0.0000000000000000000000008436 106.0
TLS3_k127_7102042_8 Pfam:Pyridox_oxidase - - - 0.00000000000000000001952 98.0
TLS3_k127_7109576_0 Secretory lipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 613.0
TLS3_k127_7109576_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 503.0
TLS3_k127_7109576_2 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 489.0
TLS3_k127_7109576_3 Pfam Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000002766 208.0
TLS3_k127_7109576_4 Putative mono-oxygenase ydhR - - - 0.0000003963 57.0
TLS3_k127_7131096_0 helicase activity - - - 4.614e-315 978.0
TLS3_k127_7131096_1 Belongs to the cysteine synthase cystathionine beta- synthase family - - - 3.164e-269 836.0
TLS3_k127_7131096_10 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 440.0
TLS3_k127_7131096_11 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 422.0
TLS3_k127_7131096_12 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 418.0
TLS3_k127_7131096_13 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 415.0
TLS3_k127_7131096_14 Sigma-70 region 3 K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 410.0
TLS3_k127_7131096_15 mannose-6-phosphate isomerase K01809 - 5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 387.0
TLS3_k127_7131096_16 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009669 356.0
TLS3_k127_7131096_17 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000586 357.0
TLS3_k127_7131096_18 Conserved hypothetical protein (DUF2461) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 328.0
TLS3_k127_7131096_19 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 291.0
TLS3_k127_7131096_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.423e-223 698.0
TLS3_k127_7131096_20 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005016 259.0
TLS3_k127_7131096_21 - - - - 0.00000000000000000000000000000000000000000000000000000000002051 234.0
TLS3_k127_7131096_22 heme binding K08259,K21472 - 3.4.24.75 0.00000000000000000000000000000000000000000007194 176.0
TLS3_k127_7131096_24 - - - - 0.00000007464 63.0
TLS3_k127_7131096_3 alcohol dehydrogenase K00153 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.306 3.393e-200 628.0
TLS3_k127_7131096_4 PFAM magnesium chelatase ChlI subunit K07391 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 608.0
TLS3_k127_7131096_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 599.0
TLS3_k127_7131096_6 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 561.0
TLS3_k127_7131096_7 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 514.0
TLS3_k127_7131096_8 Ribosomal protein S2 K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 489.0
TLS3_k127_7131096_9 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 478.0
TLS3_k127_7148496_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 599.0
TLS3_k127_7148496_1 Nad-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 509.0
TLS3_k127_7148496_10 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000001073 244.0
TLS3_k127_7148496_11 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000003384 235.0
TLS3_k127_7148496_12 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000000000000000000000000000939 196.0
TLS3_k127_7148496_13 - - - - 0.0000000000000000000000000000006949 136.0
TLS3_k127_7148496_14 Uroporphyrinogen III synthase HEM4 K01719 - 4.2.1.75 0.000000003682 67.0
TLS3_k127_7148496_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 509.0
TLS3_k127_7148496_3 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 475.0
TLS3_k127_7148496_4 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 440.0
TLS3_k127_7148496_5 transcriptional regulator K01420,K10914,K21561,K21564 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 385.0
TLS3_k127_7148496_6 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 369.0
TLS3_k127_7148496_7 RNA 2'-O ribose methyltransferase substrate binding K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 357.0
TLS3_k127_7148496_8 Phosphoribulokinase / Uridine kinase family K00855,K00876 - 2.7.1.19,2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 334.0
TLS3_k127_7148496_9 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000782 312.0
TLS3_k127_7158511_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1351.0
TLS3_k127_7158511_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.162e-272 848.0
TLS3_k127_7158511_10 lycopene cyclase K06443 - 5.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 350.0
TLS3_k127_7158511_11 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008952 353.0
TLS3_k127_7158511_12 SURF1-like protein - GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002719 266.0
TLS3_k127_7158511_13 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001511 252.0
TLS3_k127_7158511_14 Domain of unknown function (DUF4262) - - - 0.000000000000000000000000000000000000000000000000000000000000003103 235.0
TLS3_k127_7158511_15 domain, Protein K01448,K13733 - 3.5.1.28 0.000000000000000000000000000000000000005171 167.0
TLS3_k127_7158511_16 formamidopyrimidine-DNA glycosylase K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000004519 93.0
TLS3_k127_7158511_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 5.299e-269 861.0
TLS3_k127_7158511_3 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 2.528e-212 664.0
TLS3_k127_7158511_4 Peptidase S9 prolyl oligopeptidase active site - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 545.0
TLS3_k127_7158511_5 Metallo-beta-lactamase superfamily K05555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 486.0
TLS3_k127_7158511_6 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 445.0
TLS3_k127_7158511_7 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 450.0
TLS3_k127_7158511_8 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 402.0
TLS3_k127_7158511_9 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 378.0
TLS3_k127_7176520_0 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 460.0
TLS3_k127_7176520_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000001885 194.0
TLS3_k127_7176520_2 COG1520 FOG WD40-like repeat - - - 0.0002721 53.0
TLS3_k127_7253654_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.865e-221 696.0
TLS3_k127_7253654_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 3.619e-207 649.0
TLS3_k127_7253654_2 Sir2 family K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000005452 235.0
TLS3_k127_7253654_3 PFAM acyltransferase 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001916 255.0
TLS3_k127_7253654_4 DNA integration - - - 0.00005575 51.0
TLS3_k127_7286554_0 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 293.0
TLS3_k127_7286554_1 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000001847 193.0
TLS3_k127_7286554_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000002284 161.0
TLS3_k127_7331292_0 Belongs to the peptidase S26 family K13280 - 3.4.21.89 0.000000000000000000000000000000000002377 148.0
TLS3_k127_7331292_1 - - - - 0.00000000000000000000005263 113.0
TLS3_k127_7340537_0 ABC-type dipeptide transport system, periplasmic component K02035 - - 3.85e-288 899.0
TLS3_k127_7340537_1 Phosphoglycerate kinase K00927 - 2.7.2.3 5.897e-202 646.0
TLS3_k127_7340537_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 525.0
TLS3_k127_7340537_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 430.0
TLS3_k127_7340537_4 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 383.0
TLS3_k127_7361015_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 3.114e-319 979.0
TLS3_k127_7387777_0 Peptidase dimerisation domain - - - 6.084e-221 693.0
TLS3_k127_7387777_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01740,K01761 - 2.5.1.48,2.5.1.49,4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 602.0
TLS3_k127_7387777_10 GCN5-related N-acetyl-transferase K06975 - - 0.000000000000005973 79.0
TLS3_k127_7387777_11 - - - - 0.0000000000006165 81.0
TLS3_k127_7387777_12 - - - - 0.0000002024 63.0
TLS3_k127_7387777_13 - - - - 0.00000422 59.0
TLS3_k127_7387777_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000531 485.0
TLS3_k127_7387777_3 Belongs to the enoyl-CoA hydratase isomerase family K01692,K13766 - 4.2.1.17,4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 394.0
TLS3_k127_7387777_4 NifU-like domain K07400 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 366.0
TLS3_k127_7387777_5 survival protein SurE K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 364.0
TLS3_k127_7387777_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 325.0
TLS3_k127_7387777_7 peptide-methionine (R)-S-oxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000002911 234.0
TLS3_k127_7387777_8 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000000000000005 146.0
TLS3_k127_7387777_9 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000006028 133.0
TLS3_k127_7400833_0 Belongs to the peptidase S8 family - - - 0.0 1367.0
TLS3_k127_7400833_1 ABC transporter - - - 0.0 1019.0
TLS3_k127_7400833_10 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 340.0
TLS3_k127_7400833_11 lactoylglutathione lyase activity K01759,K08234 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001734 276.0
TLS3_k127_7400833_12 Ecdysteroid kinase - - - 0.000000000000000000000000000000000000000000000000000000000000504 225.0
TLS3_k127_7400833_13 - - - - 0.00000000000000000000001214 112.0
TLS3_k127_7400833_14 FMN binding - - - 0.0000000000000000000004572 102.0
TLS3_k127_7400833_2 Peptidase family M41 - - - 5.512e-308 953.0
TLS3_k127_7400833_3 ABC1 family - - - 3.221e-271 847.0
TLS3_k127_7400833_4 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 1.954e-213 672.0
TLS3_k127_7400833_5 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 556.0
TLS3_k127_7400833_6 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 442.0
TLS3_k127_7400833_7 inositol monophosphatase K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 413.0
TLS3_k127_7400833_8 related to 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009131 419.0
TLS3_k127_7400833_9 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 405.0
TLS3_k127_74272_0 Domain of unknown function (DUF3367) K16648 - - 0.0 1130.0
TLS3_k127_74272_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.234e-317 977.0
TLS3_k127_74272_10 Prephenate dehydrogenase K00210,K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 451.0
TLS3_k127_74272_11 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 414.0
TLS3_k127_74272_12 UbiA prenyltransferase family K14136 - 2.4.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 411.0
TLS3_k127_74272_13 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 396.0
TLS3_k127_74272_14 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 376.0
TLS3_k127_74272_15 RNA pseudouridylate synthase K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 373.0
TLS3_k127_74272_16 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 353.0
TLS3_k127_74272_17 Xanthine dehydrogenase iron-sulfur cluster and FAD-binding subunit A K13481 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 351.0
TLS3_k127_74272_18 Glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 368.0
TLS3_k127_74272_19 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 364.0
TLS3_k127_74272_2 Domain of unknown function (DUF3367) - - - 1.959e-236 798.0
TLS3_k127_74272_20 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 359.0
TLS3_k127_74272_21 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 338.0
TLS3_k127_74272_22 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 316.0
TLS3_k127_74272_23 KR domain K16652 - 1.1.1.333 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 288.0
TLS3_k127_74272_24 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000135 246.0
TLS3_k127_74272_25 Evidence 5 No homology to any previously reported sequences K14340 - - 0.00000000000000000000000000000000000000000000000000000000000000000005467 255.0
TLS3_k127_74272_27 haloacid dehalogenase-like hydrolase K18697 - 3.1.3.27 0.00000000000000000000000000000000000000000000000000001594 209.0
TLS3_k127_74272_3 May be involved in recombinational repair of damaged DNA K03631 - - 2.501e-202 655.0
TLS3_k127_74272_4 FAD binding domain K16653 - 1.1.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 606.0
TLS3_k127_74272_5 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 592.0
TLS3_k127_74272_6 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 531.0
TLS3_k127_74272_7 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 510.0
TLS3_k127_74272_8 MATE efflux family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 498.0
TLS3_k127_74272_9 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 470.0
TLS3_k127_7440015_0 Ribonuclease BN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009659 356.0
TLS3_k127_7440015_1 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000000000000003462 173.0
TLS3_k127_7440015_2 - - - - 0.0001282 46.0
TLS3_k127_7463081_0 Acyl-CoA dehydrogenase, C-terminal domain K14448 - 1.3.8.12 1.316e-279 870.0
TLS3_k127_7463081_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 4.064e-226 711.0
TLS3_k127_7463081_10 phosphatase activity K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 318.0
TLS3_k127_7463081_11 inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 307.0
TLS3_k127_7463081_12 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000002812 217.0
TLS3_k127_7463081_13 Sap, sulfolipid-1-addressing protein - - - 0.0000000000000000000000000000000000000000000000000000000003058 210.0
TLS3_k127_7463081_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 616.0
TLS3_k127_7463081_3 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 582.0
TLS3_k127_7463081_4 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 574.0
TLS3_k127_7463081_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009119 558.0
TLS3_k127_7463081_6 Ribonucleotide reductase, barrel domain K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 488.0
TLS3_k127_7463081_7 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007253 426.0
TLS3_k127_7463081_8 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 392.0
TLS3_k127_7463081_9 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 373.0
TLS3_k127_7473435_0 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 0.0 1114.0
TLS3_k127_7473435_1 DNA polymerase K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 616.0
TLS3_k127_7473435_10 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000000000000000002928 191.0
TLS3_k127_7473435_2 Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 374.0
TLS3_k127_7473435_3 CcmB protein K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 343.0
TLS3_k127_7473435_5 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000004482 231.0
TLS3_k127_7473435_7 cell redox homeostasis K02199 - - 0.000000000000000000000000000000000000000000000000000000000000007271 225.0
TLS3_k127_7473435_8 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000003975 211.0
TLS3_k127_7473435_9 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000003522 188.0
TLS3_k127_7660753_0 FAD binding domain K21401 - 1.3.99.38 2.25e-206 650.0
TLS3_k127_7660753_1 beta-ketoacyl-acyl-carrier-protein synthase III activity K00648,K16872 - 2.3.1.180,2.3.1.207 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 582.0
TLS3_k127_7660753_10 - - - - 0.0000000000000815 79.0
TLS3_k127_7660753_2 abc transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 469.0
TLS3_k127_7660753_3 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 461.0
TLS3_k127_7660753_4 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 399.0
TLS3_k127_7660753_5 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 394.0
TLS3_k127_7660753_6 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 394.0
TLS3_k127_7660753_7 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 302.0
TLS3_k127_7660753_8 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008849 290.0
TLS3_k127_76981_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 591.0
TLS3_k127_76981_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 557.0
TLS3_k127_76981_10 Bacterial extracellular solute-binding protein K17329 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 361.0
TLS3_k127_76981_11 Binding-protein-dependent transport system inner membrane component K02026,K17331 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 349.0
TLS3_k127_76981_12 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 353.0
TLS3_k127_76981_13 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 324.0
TLS3_k127_76981_14 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion K02564 - 3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 317.0
TLS3_k127_76981_15 exopolysaccharide biosynthesis protein K19431 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 302.0
TLS3_k127_76981_16 Lipopolysaccharide biosynthesis protein K19424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008998 299.0
TLS3_k127_76981_17 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003597 277.0
TLS3_k127_76981_18 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001359 289.0
TLS3_k127_76981_19 Bacterial transferase hexapeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006922 270.0
TLS3_k127_76981_2 ABC transporter ATP-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 529.0
TLS3_k127_76981_20 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000134 273.0
TLS3_k127_76981_21 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001759 262.0
TLS3_k127_76981_22 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005547 273.0
TLS3_k127_76981_23 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006621 257.0
TLS3_k127_76981_24 Lipopolysaccharide biosynthesis protein K19424 - - 0.0000000000000000000000000000000000000000000000000000000000000000007704 244.0
TLS3_k127_76981_25 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000008599 238.0
TLS3_k127_76981_26 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000002345 239.0
TLS3_k127_76981_27 asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000001457 233.0
TLS3_k127_76981_28 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000004983 230.0
TLS3_k127_76981_29 Ribosomal protein L11 methyltransferase (PrmA) K11434 - 2.1.1.319 0.00000000000000000000000000000000000000000000000000000000000002539 228.0
TLS3_k127_76981_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 516.0
TLS3_k127_76981_30 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000001262 216.0
TLS3_k127_76981_31 Protein of unknown function (DUF4012) - - - 0.00000000000000000000000000000000000000000000000000002155 213.0
TLS3_k127_76981_32 - - - - 0.0000000000000000000000000000000000000000000000000008448 202.0
TLS3_k127_76981_33 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000001202 196.0
TLS3_k127_76981_34 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000005253 193.0
TLS3_k127_76981_35 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000813 197.0
TLS3_k127_76981_36 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000008689 189.0
TLS3_k127_76981_37 Sugar transferases involved in lipopolysaccharide synthesis - - - 0.0000000000000000000000000000000000000000000000001315 186.0
TLS3_k127_76981_38 Sugar-transfer associated ATP-grasp - - - 0.00000000000000000000000000000000000000000000007123 185.0
TLS3_k127_76981_39 Sugar-transfer associated ATP-grasp - - - 0.0000000000000000000000000000000000000000000002246 183.0
TLS3_k127_76981_4 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007449 465.0
TLS3_k127_76981_40 biosynthesis protein K08252,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000003703 168.0
TLS3_k127_76981_41 Malate/L-lactate dehydrogenase - - - 0.000000000000000000000000000000000001718 155.0
TLS3_k127_76981_42 TIGRFAM sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family K13006 - - 0.000000000000000000000000000000000002345 147.0
TLS3_k127_76981_43 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000001251 139.0
TLS3_k127_76981_44 amine dehydrogenase activity - - - 0.0000000000000000000000000000007818 138.0
TLS3_k127_76981_45 guanyl-nucleotide exchange factor activity K20276 - - 0.00000000000000000002129 100.0
TLS3_k127_76981_46 Mur ligase family, glutamate ligase domain - - - 0.0000000000000000002363 100.0
TLS3_k127_76981_47 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.000000000001911 80.0
TLS3_k127_76981_48 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.00000004805 66.0
TLS3_k127_76981_5 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 434.0
TLS3_k127_76981_6 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 434.0
TLS3_k127_76981_7 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 410.0
TLS3_k127_76981_8 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 383.0
TLS3_k127_76981_9 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 374.0
TLS3_k127_7742620_0 N-acyl-D-aspartate D-glutamate deacylase - - - 2.836e-300 930.0
TLS3_k127_7742620_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 545.0
TLS3_k127_7742620_2 Cation transport protein K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 411.0
TLS3_k127_7742620_3 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000002502 242.0
TLS3_k127_7742620_4 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000002628 211.0
TLS3_k127_7742620_7 Bacterial PH domain - - - 0.000008844 51.0
TLS3_k127_7787187_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 544.0
TLS3_k127_7787187_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 478.0
TLS3_k127_7787187_10 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000914 275.0
TLS3_k127_7787187_11 siderophore-interacting protein - - - 0.0000000000000000000000000000000000000000000000000005692 198.0
TLS3_k127_7787187_12 Helix-turn-helix - - - 0.00000000000000000519 93.0
TLS3_k127_7787187_2 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 482.0
TLS3_k127_7787187_3 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000701 458.0
TLS3_k127_7787187_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 450.0
TLS3_k127_7787187_5 Flavodoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 407.0
TLS3_k127_7787187_6 abc transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 382.0
TLS3_k127_7787187_7 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 310.0
TLS3_k127_7787187_8 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004659 276.0
TLS3_k127_7787187_9 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005469 299.0
TLS3_k127_7789916_0 endonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 441.0
TLS3_k127_7789916_1 Hypothetical methyltransferase - - - 0.000000000000000000000000000000000000000000000004044 180.0
TLS3_k127_7789916_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000004672 119.0
TLS3_k127_7789916_3 Protein of unknown function (DUF402) K07586 - - 0.0000000000000000004199 95.0
TLS3_k127_7798289_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1233.0
TLS3_k127_7798289_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1083.0
TLS3_k127_7798289_10 Protein of unknown function (DUF3097) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 451.0
TLS3_k127_7798289_11 Histidine kinase K07653 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 450.0
TLS3_k127_7798289_12 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 416.0
TLS3_k127_7798289_13 oxidoreductase activity K21883 - 1.1.1.401 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 406.0
TLS3_k127_7798289_14 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 399.0
TLS3_k127_7798289_15 succinate dehydrogenase K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 391.0
TLS3_k127_7798289_16 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 383.0
TLS3_k127_7798289_17 Transcriptional regulatory protein, C terminal K07669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 357.0
TLS3_k127_7798289_18 purine-nucleoside phosphorylase K00772,K03784 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 346.0
TLS3_k127_7798289_2 ATPases associated with a variety of cellular activities K15738 - - 1.861e-275 858.0
TLS3_k127_7798289_20 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009831 310.0
TLS3_k127_7798289_21 Belongs to the UPF0246 family K09861 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000578 279.0
TLS3_k127_7798289_22 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000003317 244.0
TLS3_k127_7798289_23 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000003376 243.0
TLS3_k127_7798289_24 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000002624 238.0
TLS3_k127_7798289_25 FMN binding - - - 0.00000000000000000000000000000000000000000000000000000000000000001378 228.0
TLS3_k127_7798289_26 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000000000000000000000000000001517 220.0
TLS3_k127_7798289_27 Copper resistance protein CopC K14166 - - 0.0000000000000000000000000000000000000000000000000000006005 214.0
TLS3_k127_7798289_29 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000002061 168.0
TLS3_k127_7798289_3 Acyltransferase family - - - 9.018e-256 807.0
TLS3_k127_7798289_30 META domain K03668 - - 0.00000000000000000000000000000000000003224 154.0
TLS3_k127_7798289_31 - - - - 0.0000000000000000000000000000000000002004 150.0
TLS3_k127_7798289_33 Domain of unknown function (DUF305) - - - 0.000000000000000000000000000000005327 136.0
TLS3_k127_7798289_34 membrane - - - 0.00000000000000000000000000005202 124.0
TLS3_k127_7798289_35 Ferredoxin K05337 - - 0.0000000000000000000000000109 121.0
TLS3_k127_7798289_36 Domain of unknown function (DUF4349) - - - 0.0000000000000000000005243 108.0
TLS3_k127_7798289_37 Domain of unkown function (DUF1775) K09796 - - 0.0000000000000000142 92.0
TLS3_k127_7798289_38 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000004969 84.0
TLS3_k127_7798289_39 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000002113 77.0
TLS3_k127_7798289_4 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 5.032e-252 785.0
TLS3_k127_7798289_5 cytochrome P450 - - - 1.786e-237 751.0
TLS3_k127_7798289_6 Acyltransferase family - - - 1.295e-227 723.0
TLS3_k127_7798289_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 3.184e-209 654.0
TLS3_k127_7798289_8 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 545.0
TLS3_k127_7798289_9 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 533.0
TLS3_k127_7830170_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1036.0
TLS3_k127_7830170_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.71e-232 738.0
TLS3_k127_7830170_10 Acetyltransferase (GNAT) domain K00663,K03790 - 2.3.1.128,2.3.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 307.0
TLS3_k127_7830170_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 310.0
TLS3_k127_7830170_12 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 301.0
TLS3_k127_7830170_13 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 295.0
TLS3_k127_7830170_14 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003708 249.0
TLS3_k127_7830170_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 5.205e-204 660.0
TLS3_k127_7830170_3 tRNA methyl transferase K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 556.0
TLS3_k127_7830170_4 Aminotransferase class-V K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 536.0
TLS3_k127_7830170_5 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 470.0
TLS3_k127_7830170_6 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 450.0
TLS3_k127_7830170_7 inositol monophosphatase K01092,K05602 - 3.1.3.15,3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 384.0
TLS3_k127_7830170_8 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 377.0
TLS3_k127_7830170_9 ThiJ PfpI - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 314.0
TLS3_k127_7868261_0 Rhodanese Homology Domain - - - 3.087e-230 721.0
TLS3_k127_7868261_1 Major facilitator Superfamily K07552,K19577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 419.0
TLS3_k127_7868261_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 333.0
TLS3_k127_7868261_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 328.0
TLS3_k127_7868261_4 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 306.0
TLS3_k127_7868261_5 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000001513 184.0
TLS3_k127_7868261_6 PFAM Glycoside hydrolase 15-related - - - 0.0000000009836 59.0
TLS3_k127_7872816_0 Carboxyl transferase domain - - - 9.922e-285 886.0
TLS3_k127_7872816_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 533.0
TLS3_k127_7872816_2 Epoxide hydrolase N terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 512.0
TLS3_k127_7872816_3 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 318.0
TLS3_k127_7872816_4 Mur ligase family, glutamate ligase domain K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000003507 267.0
TLS3_k127_7912514_0 Alpha-amylase domain K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 545.0
TLS3_k127_7912514_1 PFAM binding-protein-dependent transport systems inner membrane component K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 429.0
TLS3_k127_7912514_2 ABC transporter K15772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 312.0
TLS3_k127_7912514_4 AlkA N-terminal domain K13529 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000003154 226.0
TLS3_k127_7912514_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000001983 220.0
TLS3_k127_7912514_6 Bacterial extracellular solute-binding protein K15770 - - 0.0000000000000000000000000000001253 127.0
TLS3_k127_7917450_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1148.0
TLS3_k127_7917450_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 8.943e-238 752.0
TLS3_k127_7917450_2 Zc3h12a-like Ribonuclease NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 492.0
TLS3_k127_7917450_3 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 420.0
TLS3_k127_7917450_4 HAD-superfamily hydrolase subfamily IA, variant 3 K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 298.0
TLS3_k127_7917450_5 - - - - 0.0000000000000000008204 100.0
TLS3_k127_7921399_0 Domain of unknown function DUF87 K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007244 606.0
TLS3_k127_7944085_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.564e-274 865.0
TLS3_k127_7944085_1 potassium ion transmembrane transporter activity K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 8.764e-205 657.0
TLS3_k127_7944085_11 RibD C-terminal domain - - - 0.00000000000000000000000000648 110.0
TLS3_k127_7944085_12 Penicillinase repressor - - - 0.00000000000000000000000001446 113.0
TLS3_k127_7944085_13 - - - - 0.00000000000000000000003728 104.0
TLS3_k127_7944085_14 Chloramphenicol phosphotransferase-like protein K18554 - - 0.000000001284 68.0
TLS3_k127_7944085_2 Ammonium Transporter Family K03320 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 456.0
TLS3_k127_7944085_3 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 376.0
TLS3_k127_7944085_4 Hydrolases of the alpha beta superfamily K06889 - - 0.0000000000000000000000000000000000000000000000000000000000006551 230.0
TLS3_k127_7944085_5 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000004668 191.0
TLS3_k127_7944085_6 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000001393 195.0
TLS3_k127_7944085_7 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000000000003139 166.0
TLS3_k127_7944085_8 metalloendopeptidase activity - - - 0.000000000000000000000000000000000000000009558 166.0
TLS3_k127_7944085_9 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000004492 138.0
TLS3_k127_7956982_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 399.0
TLS3_k127_7956982_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 392.0
TLS3_k127_7956982_2 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000003012 233.0
TLS3_k127_7981129_0 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 413.0
TLS3_k127_7981129_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007265 263.0
TLS3_k127_7981129_2 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000003122 103.0
TLS3_k127_8046450_0 Glycosyl transferases group 1 K16148 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 565.0
TLS3_k127_8046450_1 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 404.0
TLS3_k127_8046450_10 ANTAR - - - 0.0000000000000000000000000000000000000005176 160.0
TLS3_k127_8046450_11 Domain of unknown function (DUF1772) - - - 0.0000000000000000000000000000000002609 141.0
TLS3_k127_8046450_12 - - - - 0.0000000000000000000000000000001321 133.0
TLS3_k127_8046450_13 protein, hemolysin III K11068 - - 0.00000000000000000000000000000976 127.0
TLS3_k127_8046450_14 AAA domain - - - 0.00000000000000000000000005519 115.0
TLS3_k127_8046450_15 - - - - 0.00000000000000004234 92.0
TLS3_k127_8046450_16 Bacterial regulatory proteins, tetR family - - - 0.000000000000007932 82.0
TLS3_k127_8046450_17 antisigma factor binding K04749,K05946,K06378 - 2.4.1.187 0.0000006266 59.0
TLS3_k127_8046450_2 Zinc-binding dehydrogenase K00001,K00344 - 1.1.1.1,1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 349.0
TLS3_k127_8046450_3 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 355.0
TLS3_k127_8046450_4 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 343.0
TLS3_k127_8046450_5 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 317.0
TLS3_k127_8046450_6 homoserine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 319.0
TLS3_k127_8046450_7 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001032 265.0
TLS3_k127_8046450_8 ANTAR domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000004151 233.0
TLS3_k127_8046450_9 Bacterial transcriptional repressor C-terminal - - - 0.0000000000000000000000000000000000000000000000000000003713 199.0
TLS3_k127_8104430_0 Esterase of the alpha-beta hydrolase superfamily - - - 1.095e-273 866.0
TLS3_k127_8104430_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 9.584e-237 752.0
TLS3_k127_8104430_10 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001863 249.0
TLS3_k127_8104430_11 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05845 - - 0.00000000000000000000000000000000000000000000000000004031 209.0
TLS3_k127_8104430_12 phosphoesterase, PA-phosphatase K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000001005 171.0
TLS3_k127_8104430_13 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000005378 160.0
TLS3_k127_8104430_14 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000002918 163.0
TLS3_k127_8104430_15 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000002261 145.0
TLS3_k127_8104430_16 Metal-dependent hydrolase - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - 0.000000000000000000000000000000001206 137.0
TLS3_k127_8104430_17 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.000000000000000000000000000001667 134.0
TLS3_k127_8104430_18 glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000000000000000000000000115 117.0
TLS3_k127_8104430_19 glyoxalase - - - 0.00000000000000000002017 96.0
TLS3_k127_8104430_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 7.286e-222 723.0
TLS3_k127_8104430_3 cellular response to dsDNA K11211,K19302 - 2.7.1.166,3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008746 573.0
TLS3_k127_8104430_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 419.0
TLS3_k127_8104430_5 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 337.0
TLS3_k127_8104430_6 Citrate synthase K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 327.0
TLS3_k127_8104430_7 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004794 295.0
TLS3_k127_8104430_8 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000233 264.0
TLS3_k127_8104430_9 pyridoxamine 5-phosphate K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003323 254.0
TLS3_k127_8111851_0 haloacid dehalogenase-like hydrolase - - - 0.0 1252.0
TLS3_k127_8111851_1 PFAM carboxyl transferase - - - 2.616e-293 910.0
TLS3_k127_8111851_10 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 479.0
TLS3_k127_8111851_11 Short-chain dehydrogenase reductase sdr K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 419.0
TLS3_k127_8111851_12 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 424.0
TLS3_k127_8111851_13 mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 372.0
TLS3_k127_8111851_14 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 305.0
TLS3_k127_8111851_15 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 295.0
TLS3_k127_8111851_16 transcriptional regulator K09017 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 292.0
TLS3_k127_8111851_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000002438 230.0
TLS3_k127_8111851_18 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000004453 219.0
TLS3_k127_8111851_2 sulfatase - - - 6.657e-278 864.0
TLS3_k127_8111851_3 Domain of unknown function (DUF2088) - - - 2.905e-269 839.0
TLS3_k127_8111851_4 UDP binding domain K00012 - 1.1.1.22 6.877e-212 687.0
TLS3_k127_8111851_5 Voltage gated chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 577.0
TLS3_k127_8111851_6 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 575.0
TLS3_k127_8111851_7 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 563.0
TLS3_k127_8111851_8 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 532.0
TLS3_k127_8111851_9 Methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 507.0
TLS3_k127_8136455_0 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.000000000000000000000000000000000000002774 163.0
TLS3_k127_8139933_0 Predicted Permease Membrane Region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 408.0
TLS3_k127_8139933_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006787 285.0
TLS3_k127_8139933_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000003948 237.0
TLS3_k127_8201304_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008388 524.0
TLS3_k127_8201304_1 Flavin containing amine oxidoreductase K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 513.0
TLS3_k127_8201304_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006084 283.0
TLS3_k127_8201304_3 Sortase family K07284 - 3.4.22.70 0.0000000000000000000000000000000000000000000009756 188.0
TLS3_k127_8201304_4 AAA domain - - - 0.0000000000000000004379 87.0
TLS3_k127_8201304_5 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000005334 67.0
TLS3_k127_8240235_0 PFAM Glycoside hydrolase, family 38 K01191 - 3.2.1.24 3.69e-260 835.0
TLS3_k127_8240235_1 DEAD-like helicases superfamily - - - 3.416e-204 646.0
TLS3_k127_8240235_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 593.0
TLS3_k127_8240235_3 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 531.0
TLS3_k127_8240235_4 PFAM Peptidase family M20 M25 M40 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 376.0
TLS3_k127_8240235_5 dna ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 354.0
TLS3_k127_8240235_6 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 365.0
TLS3_k127_8292956_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA - - - 2.839e-235 779.0
TLS3_k127_8292956_1 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 339.0
TLS3_k127_8292956_3 amine dehydrogenase activity - - - 0.00000000000000000001169 94.0
TLS3_k127_8292956_4 Protein of unknown function, DUF255 K06888 - - 0.0000000000000001976 91.0
TLS3_k127_8352253_0 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 466.0
TLS3_k127_8352253_1 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 323.0
TLS3_k127_8352253_2 COGs COG1819 Glycosyl transferase related to UDP-glucuronosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008269 243.0
TLS3_k127_8386960_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 321.0
TLS3_k127_8386960_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 308.0
TLS3_k127_8386960_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007807 325.0
TLS3_k127_8386960_3 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000002828 160.0
TLS3_k127_8386960_4 Subtilase family - - - 0.000000000000000000000000000009671 134.0
TLS3_k127_8585861_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1243.0
TLS3_k127_8585861_1 transporter K12942 - - 2.911e-196 630.0
TLS3_k127_8585861_10 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000142 86.0
TLS3_k127_8585861_11 - - - - 0.000000000000001345 84.0
TLS3_k127_8585861_2 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 552.0
TLS3_k127_8585861_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 491.0
TLS3_k127_8585861_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 407.0
TLS3_k127_8585861_5 Glutaminase K01425 - 3.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 390.0
TLS3_k127_8585861_6 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 322.0
TLS3_k127_8585861_7 Phosphotransferase enzyme family K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005233 295.0
TLS3_k127_8585861_8 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000004168 211.0
TLS3_k127_8585861_9 Cbs domain - - - 0.00000000000000000000000000000000000000000000000000001873 192.0
TLS3_k127_860629_0 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000007613 217.0
TLS3_k127_860629_1 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000003705 143.0
TLS3_k127_860629_2 Domain of unknown function (DUF427) - - - 0.0000000000000000000000001313 108.0
TLS3_k127_870280_0 AlkA N-terminal domain K13529 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 452.0
TLS3_k127_870280_1 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 445.0
TLS3_k127_870280_2 Transglutaminase/protease-like homologues - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000007404 184.0
TLS3_k127_870280_3 - - - - 0.0000000000000002597 89.0
TLS3_k127_870280_4 protein encoded in hypervariable junctions of pilus gene clusters - - - 0.0000000004585 68.0
TLS3_k127_879392_0 Bacterial transcriptional activator domain - - - 1.257e-284 914.0
TLS3_k127_879392_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 2.045e-238 741.0
TLS3_k127_879392_10 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 381.0
TLS3_k127_879392_11 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 359.0
TLS3_k127_879392_12 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 357.0
TLS3_k127_879392_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 331.0
TLS3_k127_879392_14 ABC transporter K02049,K10831,K15555 - 3.6.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 328.0
TLS3_k127_879392_15 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 322.0
TLS3_k127_879392_16 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 320.0
TLS3_k127_879392_17 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 313.0
TLS3_k127_879392_18 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001529 314.0
TLS3_k127_879392_19 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002796 281.0
TLS3_k127_879392_2 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008273 554.0
TLS3_k127_879392_20 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002462 275.0
TLS3_k127_879392_21 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007329 273.0
TLS3_k127_879392_22 A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics - - - 0.00000000000000000000000000000000000000000000000000000000000000000000147 253.0
TLS3_k127_879392_23 ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000008966 245.0
TLS3_k127_879392_24 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000004097 240.0
TLS3_k127_879392_25 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000007244 223.0
TLS3_k127_879392_26 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000006653 231.0
TLS3_k127_879392_27 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000002835 219.0
TLS3_k127_879392_28 Prokaryotic cytochrome b561 K12262 - - 0.00000000000000000000000000000000000000000000000000000000005182 216.0
TLS3_k127_879392_29 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000001493 216.0
TLS3_k127_879392_3 PFAM aldo keto reductase K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 526.0
TLS3_k127_879392_30 A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics - - - 0.000000000000000000000000000000000000000000000000000000002278 211.0
TLS3_k127_879392_31 PFAM Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000001261 199.0
TLS3_k127_879392_32 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000001625 191.0
TLS3_k127_879392_33 lactoylglutathione lyase activity K01759 GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 4.4.1.5 0.0000000000000000000000000000000000000000000000005247 183.0
TLS3_k127_879392_34 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000006939 179.0
TLS3_k127_879392_35 dehydratase - - - 0.0000000000000000000000000000000000000000000005484 181.0
TLS3_k127_879392_36 helix_turn_helix, cAMP Regulatory protein - - - 0.000000000000000000000000000000000000000003769 177.0
TLS3_k127_879392_37 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000005824 167.0
TLS3_k127_879392_38 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000043 153.0
TLS3_k127_879392_39 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000002603 147.0
TLS3_k127_879392_4 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 529.0
TLS3_k127_879392_40 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000001983 143.0
TLS3_k127_879392_41 Rho termination factor - - - 0.0000000000000000000000000000000003881 134.0
TLS3_k127_879392_42 ECF sigma factor K03088 - - 0.00000000000000000000000000000002707 133.0
TLS3_k127_879392_43 - - - - 0.00000000000000000000000000000003446 138.0
TLS3_k127_879392_44 YdjC-like protein K03478 - 3.5.1.105 0.00000000000000000000000005601 118.0
TLS3_k127_879392_45 AzlC protein - - - 0.0000000000000000000002717 106.0
TLS3_k127_879392_46 transcriptional regulator - - - 0.0000000000003311 79.0
TLS3_k127_879392_47 phosphorelay signal transduction system - - - 0.0000000000009078 82.0
TLS3_k127_879392_48 outer membrane autotransporter barrel domain K12685 - - 0.0000004699 65.0
TLS3_k127_879392_5 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 465.0
TLS3_k127_879392_6 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006621 467.0
TLS3_k127_879392_7 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009637 464.0
TLS3_k127_879392_8 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 453.0
TLS3_k127_879392_9 PFAM chorismate K01665,K03342 - 2.6.1.85,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 442.0
TLS3_k127_885013_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1514.0
TLS3_k127_885013_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 1.376e-195 614.0
TLS3_k127_885013_11 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000028 65.0
TLS3_k127_885013_2 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 458.0
TLS3_k127_885013_3 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 451.0
TLS3_k127_885013_4 ATPases associated with a variety of cellular activities K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 430.0
TLS3_k127_885013_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 304.0
TLS3_k127_885013_6 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001745 281.0
TLS3_k127_885013_7 competence protein K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000005329 243.0
TLS3_k127_885013_8 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000002238 232.0
TLS3_k127_885013_9 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000000000000000000000000000000444 134.0
TLS3_k127_925281_0 ABC transporter, transmembrane region K06147 - - 1.945e-238 753.0
TLS3_k127_925281_1 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 2.521e-220 692.0
TLS3_k127_925281_10 Redoxin - - - 0.00000000000000000000000000000000000000000005736 168.0
TLS3_k127_925281_11 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000902 158.0
TLS3_k127_925281_12 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000153 90.0
TLS3_k127_925281_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 586.0
TLS3_k127_925281_3 Cytochrome c biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 351.0
TLS3_k127_925281_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K00219,K01069 - 1.3.1.34,3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 340.0
TLS3_k127_925281_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 318.0
TLS3_k127_925281_6 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 303.0
TLS3_k127_925281_7 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003281 282.0
TLS3_k127_925281_8 Activator of Hsp90 ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004085 259.0
TLS3_k127_925281_9 Iron-sulphur cluster biosynthesis K13628 - - 0.0000000000000000000000000000000000000000000000000000002937 198.0
TLS3_k127_941064_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18 0.0 1023.0
TLS3_k127_941064_1 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 3.02e-289 906.0
TLS3_k127_941064_10 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 5.897e-222 713.0
TLS3_k127_941064_11 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 7.035e-220 694.0
TLS3_k127_941064_12 Homoserine dehydrogenase K00003 - 1.1.1.3 5.766e-217 684.0
TLS3_k127_941064_13 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 5.776e-215 677.0
TLS3_k127_941064_14 Arginyl-tRNA synthetase K01887 - 6.1.1.19 1.865e-208 664.0
TLS3_k127_941064_15 Major facilitator Superfamily K08369 - - 3.115e-207 664.0
TLS3_k127_941064_16 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 596.0
TLS3_k127_941064_17 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007189 554.0
TLS3_k127_941064_18 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 541.0
TLS3_k127_941064_19 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 541.0
TLS3_k127_941064_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.399e-289 893.0
TLS3_k127_941064_20 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 541.0
TLS3_k127_941064_21 PFAM Glycosyl transferase, group 1 K16150 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 544.0
TLS3_k127_941064_22 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 517.0
TLS3_k127_941064_23 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 520.0
TLS3_k127_941064_24 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 485.0
TLS3_k127_941064_25 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 479.0
TLS3_k127_941064_26 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 465.0
TLS3_k127_941064_27 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 461.0
TLS3_k127_941064_28 nucleoside hydrolase K01239,K01250,K10213 - 3.2.2.1,3.2.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 430.0
TLS3_k127_941064_29 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 421.0
TLS3_k127_941064_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 4.12e-273 847.0
TLS3_k127_941064_30 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 383.0
TLS3_k127_941064_31 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 382.0
TLS3_k127_941064_32 Methyltransferase small domain K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 370.0
TLS3_k127_941064_33 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 346.0
TLS3_k127_941064_34 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007068 353.0
TLS3_k127_941064_35 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 294.0
TLS3_k127_941064_36 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 300.0
TLS3_k127_941064_37 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001898 278.0
TLS3_k127_941064_38 - K09957 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005396 258.0
TLS3_k127_941064_39 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000005655 250.0
TLS3_k127_941064_4 Putative modulator of DNA gyrase K03568 - - 1.956e-254 794.0
TLS3_k127_941064_40 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002144 229.0
TLS3_k127_941064_41 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000001631 222.0
TLS3_k127_941064_42 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000162 216.0
TLS3_k127_941064_43 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000002408 205.0
TLS3_k127_941064_44 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000005775 201.0
TLS3_k127_941064_45 Thioesterase - - - 0.00000000000000000000000000000000000000000000000000223 185.0
TLS3_k127_941064_46 proton-transporting ATP synthase activity, rotational mechanism K02114 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000764 176.0
TLS3_k127_941064_47 PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - 0.000000000000000000000000000000000000000000000148 179.0
TLS3_k127_941064_48 Hydrolase of the alpha beta-hydrolase K07020 - - 0.000000000000000000000000000000000000000000002568 170.0
TLS3_k127_941064_49 endonuclease activity - - - 0.00000000000000000000000000000000000000000007026 160.0
TLS3_k127_941064_5 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.154e-243 767.0
TLS3_k127_941064_50 PHP-associated K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000001202 168.0
TLS3_k127_941064_52 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.00000000000000000000000000000000000000004944 158.0
TLS3_k127_941064_53 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000009195 168.0
TLS3_k127_941064_54 NifU-like domain - - - 0.000000000000000000000000000000000001384 139.0
TLS3_k127_941064_55 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000000000009175 145.0
TLS3_k127_941064_56 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000102 143.0
TLS3_k127_941064_57 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000002774 141.0
TLS3_k127_941064_59 Regulatory protein, FmdB family - - - 0.000000000000000000000003624 116.0
TLS3_k127_941064_6 Putative modulator of DNA gyrase K03592 - - 8.506e-241 751.0
TLS3_k127_941064_7 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 5.61e-230 719.0
TLS3_k127_941064_8 phosphorylase K00688 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.4.1.1 1.987e-229 736.0
TLS3_k127_941064_9 Threonine synthase K01733 - 4.2.3.1 2.659e-227 710.0