Overview

ID MAG04041
Name TLS3_bin.17
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Actinomycetota
Class Acidimicrobiia
Order Acidimicrobiales
Family UBA8139
Genus
Species
Assembly information
Completeness (%) 87.12
Contamination (%) 4.05
GC content (%) 69.0
N50 (bp) 4,319
Genome size (bp) 3,150,394

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3241

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1022634_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 354.0
TLS3_k127_1022634_1 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002061 251.0
TLS3_k127_1022634_2 stress protein (general stress protein 26) - - - 0.000000003929 57.0
TLS3_k127_1027536_0 Protein of unknown function (DUF1214) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004757 276.0
TLS3_k127_1027536_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000003097 116.0
TLS3_k127_1035796_0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 500.0
TLS3_k127_1035796_1 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 300.0
TLS3_k127_1035796_2 ABC-2 type transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008475 290.0
TLS3_k127_1035796_3 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000002188 246.0
TLS3_k127_1035796_4 Domain of unknown function (DUF4397) - - - 0.0008097 47.0
TLS3_k127_1056815_0 - - - - 0.00000000000000000000000000000000000000000000000002391 188.0
TLS3_k127_1056815_1 HIT domain K19710 - 2.7.7.53 0.0000000000000000000000000000000000001706 143.0
TLS3_k127_105800_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 365.0
TLS3_k127_105800_1 PFAM helix-turn-helix domain protein - - - 0.000000000000000000000000000000000000000000000000000000001942 205.0
TLS3_k127_105800_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.0000000000000000000000000000003513 131.0
TLS3_k127_1064557_0 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008676 504.0
TLS3_k127_1064557_1 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 350.0
TLS3_k127_1064557_2 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000174 205.0
TLS3_k127_1064557_3 tetR family - - - 0.000000000000003437 83.0
TLS3_k127_1077461_0 Belongs to the ABC transporter superfamily K02017,K02018 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 352.0
TLS3_k127_1077461_1 Molybdate ABC transporter K02017,K02018 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001076 274.0
TLS3_k127_1077461_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005046 254.0
TLS3_k127_1077461_3 - - - - 0.000000000000000000000000000000000000000000000000000001598 200.0
TLS3_k127_1077461_4 - - - - 0.000000000000000000000000006322 113.0
TLS3_k127_1091691_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 4.592e-253 789.0
TLS3_k127_1095046_0 Belongs to the long-chain O-acyltransferase family K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 458.0
TLS3_k127_1095046_1 DNA alkylation repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009281 247.0
TLS3_k127_1095046_2 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000000000000000000000000192 210.0
TLS3_k127_1095046_3 Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006104,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000002144 203.0
TLS3_k127_1095046_4 Protein of unknown function (DUF429) - - - 0.00000000000000000000000000000000009477 146.0
TLS3_k127_1095046_5 Large family of predicted nucleotide-binding domains K07175 - - 0.0000000000000184 76.0
TLS3_k127_1110779_0 PFAM Amidohydrolase 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 598.0
TLS3_k127_1110779_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 464.0
TLS3_k127_1110779_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000002449 187.0
TLS3_k127_1111241_0 AMP-binding enzyme C-terminal domain K18687 - 6.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 563.0
TLS3_k127_1118249_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 390.0
TLS3_k127_1118249_1 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 351.0
TLS3_k127_1118249_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007923 274.0
TLS3_k127_1118249_3 Pfam SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000009242 238.0
TLS3_k127_1118249_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000002431 100.0
TLS3_k127_1118249_5 - - - - 0.0000000002791 71.0
TLS3_k127_1118249_6 PEP-utilising enzyme, mobile domain - - - 0.0000000958 58.0
TLS3_k127_1122421_0 Cytochrome P450 - GO:0003674,GO:0003824,GO:0004497,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0046164,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 509.0
TLS3_k127_1122421_1 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 399.0
TLS3_k127_1122421_2 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 325.0
TLS3_k127_1122421_3 PFAM YibE F-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003832 262.0
TLS3_k127_1122421_4 - - - - 0.000000000000000000000000000000001666 140.0
TLS3_k127_1122421_5 Abortive infection protein K07052 - - 0.0000000000000000000004614 101.0
TLS3_k127_1122421_6 PFAM GGDEF domain containing protein - - - 0.00000000000000003197 92.0
TLS3_k127_1122421_7 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000001108 57.0
TLS3_k127_1127920_0 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 291.0
TLS3_k127_1127920_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008155 278.0
TLS3_k127_1154577_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 390.0
TLS3_k127_1158773_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 496.0
TLS3_k127_1158773_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008841 432.0
TLS3_k127_1158773_10 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000002142 182.0
TLS3_k127_1158773_11 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.00000000000000000000000000000000000001363 156.0
TLS3_k127_1158773_12 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000004221 147.0
TLS3_k127_1158773_13 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000000000007966 130.0
TLS3_k127_1158773_14 Protein of unknown function (DUF3445) K22342 - 1.14.13.238 0.0000000000000000000000000000004539 129.0
TLS3_k127_1158773_15 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000142 132.0
TLS3_k127_1158773_16 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000002057 110.0
TLS3_k127_1158773_17 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001445 112.0
TLS3_k127_1158773_18 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000001196 81.0
TLS3_k127_1158773_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 293.0
TLS3_k127_1158773_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002774 287.0
TLS3_k127_1158773_4 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000409 271.0
TLS3_k127_1158773_5 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001255 251.0
TLS3_k127_1158773_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000000000004827 233.0
TLS3_k127_1158773_7 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000002315 240.0
TLS3_k127_1158773_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001919 202.0
TLS3_k127_1158773_9 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000000000000001407 180.0
TLS3_k127_1171807_0 transferase activity, transferring glycosyl groups K20444 - - 4.774e-318 1009.0
TLS3_k127_1171807_1 PFAM ABC transporter related K01990,K09691,K09693 - 3.6.3.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 409.0
TLS3_k127_1171807_2 glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009638 273.0
TLS3_k127_1171807_3 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000009912 229.0
TLS3_k127_1171807_4 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000003499 213.0
TLS3_k127_1171807_5 Predicted membrane protein (DUF2142) - - - 0.000000000000000000000000000000000000000000000000004184 198.0
TLS3_k127_1171807_6 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000009719 181.0
TLS3_k127_1178908_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 607.0
TLS3_k127_1178908_1 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 459.0
TLS3_k127_1178908_2 B12 binding domain K14447 - 5.4.99.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 386.0
TLS3_k127_1178908_3 Calcineurin-like phosphoesterase K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 347.0
TLS3_k127_1178908_4 GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002318 275.0
TLS3_k127_1178908_5 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000000001074 181.0
TLS3_k127_1195200_0 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 - 6.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 479.0
TLS3_k127_1195200_1 WYL domain K13573 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001021 285.0
TLS3_k127_1195200_2 WYL domain K13572,K13573 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000055 240.0
TLS3_k127_1199273_0 Polyprenyl synthetase K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009236 343.0
TLS3_k127_1199273_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001215 260.0
TLS3_k127_1199273_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000001794 66.0
TLS3_k127_1199329_0 drug exporters of the RND superfamily K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009098 533.0
TLS3_k127_120286_0 GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 438.0
TLS3_k127_120286_1 Acyl-CoA dehydrogenase, C-terminal domain K00248,K14448 - 1.3.8.1,1.3.8.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 377.0
TLS3_k127_120286_2 endonuclease III K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007595 302.0
TLS3_k127_120286_3 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001379 256.0
TLS3_k127_120286_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000007386 201.0
TLS3_k127_1212798_0 helix_turn_helix, Deoxyribose operon repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 370.0
TLS3_k127_1212798_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 347.0
TLS3_k127_1212798_2 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA - - - 0.00000000000000000000000000000000000000000000007082 177.0
TLS3_k127_1212798_3 PFAM Uncharacterised protein family UPF0182 K09118 - - 0.000000000000000000000000000000000000000000002972 177.0
TLS3_k127_1212798_4 OsmC-like protein - - - 0.000000000000000000000000000000000004443 139.0
TLS3_k127_1221_0 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 547.0
TLS3_k127_1221_1 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000001886 119.0
TLS3_k127_1221_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000003836 108.0
TLS3_k127_1224027_0 Belongs to the binding-protein-dependent transport system permease family - - - 6.678e-274 854.0
TLS3_k127_1224027_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000001332 223.0
TLS3_k127_1224027_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000001015 78.0
TLS3_k127_122540_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0 1235.0
TLS3_k127_122540_1 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000001889 126.0
TLS3_k127_122540_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000001029 52.0
TLS3_k127_1242382_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 3.062e-204 640.0
TLS3_k127_1242382_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 518.0
TLS3_k127_1242382_2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000001482 246.0
TLS3_k127_1242382_3 Tryptophan synthase alpha chain K01695 - 4.2.1.20 0.000000000000004534 79.0
TLS3_k127_1249223_0 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 481.0
TLS3_k127_1249223_1 Belongs to the ABC transporter superfamily K02031,K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 470.0
TLS3_k127_1249223_2 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 352.0
TLS3_k127_1249223_3 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000215 255.0
TLS3_k127_1249223_4 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K00567,K01247 - 2.1.1.63,3.2.2.21 0.000000000000000000000000000000000000000000000000001586 191.0
TLS3_k127_1249223_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000002785 186.0
TLS3_k127_1249223_6 Bacterial regulatory proteins, tetR family - - - 0.00000000000000001495 91.0
TLS3_k127_1249223_7 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000136 50.0
TLS3_k127_1254910_0 PFAM regulatory protein LuxR K03556 - - 1.008e-296 946.0
TLS3_k127_1254910_1 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004682 280.0
TLS3_k127_1254910_2 Domain of unknown function (DUF4386) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006108 260.0
TLS3_k127_1254910_3 - - - - 0.00000000000000000000003164 104.0
TLS3_k127_1273713_0 Cation transport protein K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 433.0
TLS3_k127_1273713_1 TrkA-C domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000005887 237.0
TLS3_k127_1276223_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008172 597.0
TLS3_k127_1276223_1 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000000000003471 181.0
TLS3_k127_1276223_2 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000004276 175.0
TLS3_k127_1276223_3 Mannose-6-phosphate isomerase K01809,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000002225 152.0
TLS3_k127_1281269_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 381.0
TLS3_k127_1281269_1 DnaJ molecular chaperone homology domain - - - 0.000000625 58.0
TLS3_k127_1283407_0 AMP-dependent synthetase - - - 8.767e-214 683.0
TLS3_k127_1305664_0 PFAM amine oxidase - - - 1.655e-234 736.0
TLS3_k127_1305664_1 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009783 430.0
TLS3_k127_1305664_2 Domain of unknown function (DUF3367) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 356.0
TLS3_k127_1305664_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007231 276.0
TLS3_k127_1305664_4 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000006164 216.0
TLS3_k127_1305664_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000001104 106.0
TLS3_k127_1305664_6 Uncharacterized conserved protein (DUF2304) K09153 - - 0.00000000000000001378 89.0
TLS3_k127_1322785_0 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 532.0
TLS3_k127_1322785_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000006202 100.0
TLS3_k127_1322785_2 pfam chad - - - 0.000000000005943 71.0
TLS3_k127_1325585_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 358.0
TLS3_k127_1325585_1 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001305 260.0
TLS3_k127_1325585_2 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000006147 218.0
TLS3_k127_1325585_3 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000000000000000000000000000000001506 217.0
TLS3_k127_1325585_5 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000008836 101.0
TLS3_k127_1325585_6 - - - - 0.000000000000000003639 95.0
TLS3_k127_1325585_7 Glycosyl transferase 4-like domain - - - 0.00000000000000007085 84.0
TLS3_k127_1329798_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1017.0
TLS3_k127_1329798_1 TIGRFAM Malto-oligosyltrehalose synthase K06044 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576 5.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 514.0
TLS3_k127_1329798_2 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 304.0
TLS3_k127_1329798_3 Universal stress protein family - - - 0.0001416 44.0
TLS3_k127_1331298_0 Protein of unknown function (DUF1298) K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 442.0
TLS3_k127_1331298_1 Rieske 2Fe-2S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000434 281.0
TLS3_k127_1336785_0 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 549.0
TLS3_k127_1336785_1 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.00000000000000000000000000000000000000000000004732 176.0
TLS3_k127_1336785_2 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833,K19563 - 2.6.1.105,2.6.1.62 0.0000000000000000000000000000000000000000000002521 179.0
TLS3_k127_1336785_3 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000001886 103.0
TLS3_k127_1338492_0 cytochrome P450 - - - 1.179e-213 679.0
TLS3_k127_1338492_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 557.0
TLS3_k127_1338492_2 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 533.0
TLS3_k127_1338492_3 dihydrodipicolinate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 505.0
TLS3_k127_1338492_4 NADPH quinone K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 393.0
TLS3_k127_1338492_5 Enoyl-CoA hydratase/isomerase K08299 - 4.2.1.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 304.0
TLS3_k127_1338492_6 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000004675 213.0
TLS3_k127_1353978_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 410.0
TLS3_k127_1353978_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009837 288.0
TLS3_k127_1381876_0 phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 427.0
TLS3_k127_1381876_1 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 339.0
TLS3_k127_1381876_2 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 304.0
TLS3_k127_1401497_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 4.904e-211 660.0
TLS3_k127_1401497_1 cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001111 250.0
TLS3_k127_1416747_0 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008192 416.0
TLS3_k127_1420498_0 Predicted membrane protein (DUF2254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 456.0
TLS3_k127_1420498_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000002444 195.0
TLS3_k127_1420498_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000000001431 169.0
TLS3_k127_1420498_4 helix_turn_helix, mercury resistance - - - 0.000000000000000000000002891 109.0
TLS3_k127_1420498_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000001757 97.0
TLS3_k127_1420498_6 STAS domain K04749 - - 0.0000000000000296 78.0
TLS3_k127_1420498_7 ANTAR - - - 0.000000007035 57.0
TLS3_k127_1425729_0 Sulfatase K01137 - 3.1.6.14 0.000000000000000000000000000000000000008271 169.0
TLS3_k127_1425729_1 Sulfatase K01137 - 3.1.6.14 0.0000000000000000000000000000000000001323 164.0
TLS3_k127_1425729_2 Putative Ig domain - - - 0.00000000000000000000000000003108 138.0
TLS3_k127_1425729_3 Immunoglobulin like K12567 GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951 2.7.11.1 0.0000000000005951 83.0
TLS3_k127_1425729_4 cellulase activity - - - 0.00001878 59.0
TLS3_k127_1428264_0 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 512.0
TLS3_k127_1428264_1 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 344.0
TLS3_k127_1428264_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000005424 84.0
TLS3_k127_143443_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 308.0
TLS3_k127_145431_0 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 343.0
TLS3_k127_145431_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000001144 194.0
TLS3_k127_145431_2 Cytidylyltransferase - - - 0.0000000000000000000000000000000000000000001361 167.0
TLS3_k127_145431_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000001767 169.0
TLS3_k127_145431_4 Glycosyltransferase like family 2 K12988 - - 0.000000000000000000000000000000000001115 151.0
TLS3_k127_145431_5 COG0363 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase K01057 - 3.1.1.31 0.00000000000000000000000000004107 132.0
TLS3_k127_145431_6 Glycosyl transferase, family 2 K07011 - - 0.000003869 56.0
TLS3_k127_1465101_0 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 309.0
TLS3_k127_1465101_1 Reductase C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000905 237.0
TLS3_k127_1465101_2 YhhN family - - - 0.00000000000000000000000000000000000000000006945 176.0
TLS3_k127_1484112_0 Belongs to the pirin family K06911 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 310.0
TLS3_k127_1484112_1 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000002315 136.0
TLS3_k127_1484112_2 Belongs to the UPF0312 family - - - 0.00000000000000003765 85.0
TLS3_k127_148449_0 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 356.0
TLS3_k127_148449_1 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007271 329.0
TLS3_k127_148449_2 acetylesterase activity K01046 - 3.1.1.3 0.0000000000000000000000000000000000000000000004945 187.0
TLS3_k127_1488728_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 307.0
TLS3_k127_1488728_1 - - - - 0.000004154 56.0
TLS3_k127_1489073_0 AMP-binding enzyme - - - 1.138e-218 694.0
TLS3_k127_1489073_1 Cytochrome c oxidase subunit IV - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000002863 58.0
TLS3_k127_1489073_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.000007112 48.0
TLS3_k127_1495662_0 transglutaminase - - - 0.00000000000000000000000000000000000000000000000000000000000000003694 230.0
TLS3_k127_1495662_1 Right handed beta helix region - - - 0.000000000000000000000000000000000000000000003725 181.0
TLS3_k127_1495662_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000006361 48.0
TLS3_k127_1508010_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 2.201e-226 707.0
TLS3_k127_1508010_1 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.0000000000000000000000000000000000000006356 165.0
TLS3_k127_1508010_2 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.000000000000000000000000000000000000008217 147.0
TLS3_k127_1508010_3 RDD family - - - 0.00001817 58.0
TLS3_k127_1511945_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 512.0
TLS3_k127_1511945_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000002227 216.0
TLS3_k127_1511945_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000000044 189.0
TLS3_k127_1511945_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000003205 129.0
TLS3_k127_1511945_4 ABC transporter, ATP-binding protein K01990 - - 0.00000000006253 67.0
TLS3_k127_1514479_0 Mg2 transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 339.0
TLS3_k127_1514479_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000006969 196.0
TLS3_k127_1514479_2 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000000000000009576 153.0
TLS3_k127_1514479_3 Protein of unknown function (DUF1697) - - - 0.00000000000000000000000000000003939 138.0
TLS3_k127_1514479_4 Protein of unknown function (DUF1269) - - - 0.00000415 51.0
TLS3_k127_1555447_0 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 505.0
TLS3_k127_1555447_1 Platelet-activating factor acetylhydrolase, isoform II - - - 0.0000000000000000000000000000000000000000000000000000001314 220.0
TLS3_k127_1555447_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000001754 211.0
TLS3_k127_1555447_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000001542 177.0
TLS3_k127_1555447_4 SnoaL-like domain - - - 0.00000000000000000000000000000000000000002049 163.0
TLS3_k127_1556845_0 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 306.0
TLS3_k127_1556845_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000009167 252.0
TLS3_k127_1560104_0 haloacid dehalogenase-like hydrolase - - - 8.707e-297 925.0
TLS3_k127_1560104_1 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 402.0
TLS3_k127_1560104_2 transcriptional regulator K09017 - - 0.0000000000000000000000000000000000000000003669 165.0
TLS3_k127_1560104_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000001177 80.0
TLS3_k127_1560104_4 Virulence factor BrkB - - - 0.0000000000000004066 89.0
TLS3_k127_1568930_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 428.0
TLS3_k127_1568930_1 Haloacid dehalogenase-like hydrolase K20866 - 3.1.3.10 0.0000000000000000000000000000000000000000000000000000005183 199.0
TLS3_k127_1568930_2 ATPases associated with a variety of cellular activities K09812 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000002504 142.0
TLS3_k127_1570286_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 289.0
TLS3_k127_1570286_1 - - - - 0.0000000000000000000000000000000000000001003 157.0
TLS3_k127_1570286_2 ErfK YbiS YcfS YnhG family protein - - - 0.0000000004954 60.0
TLS3_k127_159729_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 604.0
TLS3_k127_159729_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.0000000000000000001491 89.0
TLS3_k127_1598525_0 FAD linked oxidases, C-terminal domain K00104 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 592.0
TLS3_k127_1598525_1 Belongs to the TPP enzyme family K01652 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0030312,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 392.0
TLS3_k127_1603776_0 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008922 526.0
TLS3_k127_1603776_1 acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 505.0
TLS3_k127_1603776_2 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 307.0
TLS3_k127_1603776_3 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000006698 225.0
TLS3_k127_1603776_4 regulatory protein, tetR - - - 0.0000000000000000000000000000000002914 152.0
TLS3_k127_1603776_5 - - - - 0.0000000000001353 78.0
TLS3_k127_1609880_0 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000002152 92.0
TLS3_k127_1609880_1 DNA RNA non-specific endonuclease - - - 0.00000000001919 75.0
TLS3_k127_1624775_0 C-terminal domain of 1-Cys peroxiredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 359.0
TLS3_k127_1624775_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000001071 58.0
TLS3_k127_1624775_2 - - - - 0.00001029 52.0
TLS3_k127_1659070_0 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 486.0
TLS3_k127_1661784_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.909e-220 694.0
TLS3_k127_1661784_1 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 9.157e-210 657.0
TLS3_k127_1661784_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 405.0
TLS3_k127_1661784_3 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000007262 170.0
TLS3_k127_1661784_5 Alpha beta hydrolase - - - 0.0000000000003174 70.0
TLS3_k127_1713496_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 1.558e-228 712.0
TLS3_k127_1713496_1 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 364.0
TLS3_k127_1713496_2 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000634 219.0
TLS3_k127_1724228_0 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000001995 227.0
TLS3_k127_1724228_1 Oxidoreductase FAD-binding domain K00529,K02613 GO:0000166,GO:0003674,GO:0005488,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0036094,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0097159,GO:0098754,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 1.18.1.3 0.000000000000000000000000000000000000000001285 166.0
TLS3_k127_1724228_2 Universal stress protein family - - - 0.0000000000001075 83.0
TLS3_k127_1724228_3 MDMPI C-terminal domain - - - 0.00007828 46.0
TLS3_k127_1749483_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 4.061e-288 908.0
TLS3_k127_1749483_1 alcohol dehydrogenase K13953,K18382 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 511.0
TLS3_k127_1749483_11 RDD family - - - 0.0001918 54.0
TLS3_k127_1749483_2 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 349.0
TLS3_k127_1749483_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000001173 231.0
TLS3_k127_1749483_4 response to copper ion - - - 0.0000000000000000000000000000000000000000000000000003664 196.0
TLS3_k127_1749483_6 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000005328 106.0
TLS3_k127_1749483_7 transferase activity, transferring glycosyl groups - - - 0.000000000000000000001013 108.0
TLS3_k127_1749483_8 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000005135 102.0
TLS3_k127_1749483_9 Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system - - - 0.000000000000000001826 93.0
TLS3_k127_1750957_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 334.0
TLS3_k127_1750957_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 334.0
TLS3_k127_1750957_2 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000009571 177.0
TLS3_k127_1769533_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 343.0
TLS3_k127_1769533_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000635 223.0
TLS3_k127_1769533_2 Copper resistance protein CopC K14166 - - 0.000000000000000000000000000000000000000000000000000000000624 227.0
TLS3_k127_1769533_3 Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000005228 196.0
TLS3_k127_1769533_4 ECF sigma factor K03088 - - 0.00000000000000000000000000000000002836 143.0
TLS3_k127_1769533_5 integral membrane protein - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000255 120.0
TLS3_k127_1769533_6 Domain of unkown function (DUF1775) - - - 0.000000000000000005591 95.0
TLS3_k127_1769533_7 domain, Protein - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000003858 86.0
TLS3_k127_1770679_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.504e-219 686.0
TLS3_k127_1770679_1 Phosphoribosylglycinamide synthetase, C domain K01945,K11788 GO:0008150,GO:0040007 6.3.3.1,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001114 276.0
TLS3_k127_1771560_0 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 376.0
TLS3_k127_1771560_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000001829 120.0
TLS3_k127_1771560_2 Belongs to the 'phage' integrase family K04763 - - 0.00000001255 62.0
TLS3_k127_1772563_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.067e-278 865.0
TLS3_k127_1772563_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 290.0
TLS3_k127_1772563_2 NUDIX domain - - - 0.0000000000000000000000000000000000000000000178 171.0
TLS3_k127_1772563_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000002371 162.0
TLS3_k127_1772563_4 Ion channel - - - 0.0000000000000000000000002838 117.0
TLS3_k127_1772563_5 Alpha beta hydrolase - - - 0.0000000000000000000001292 98.0
TLS3_k127_1772899_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 591.0
TLS3_k127_1772899_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 529.0
TLS3_k127_1772899_2 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000009406 231.0
TLS3_k127_1772899_3 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000001043 105.0
TLS3_k127_1779324_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 561.0
TLS3_k127_1779324_1 transferase activity, transferring glycosyl groups K03208 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 478.0
TLS3_k127_1779324_2 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 379.0
TLS3_k127_1779324_3 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 336.0
TLS3_k127_1779324_4 4-epimerase K01710,K01784 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.46,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 327.0
TLS3_k127_1779324_5 F420-0:Gamma-glutamyl ligase K12234 GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 298.0
TLS3_k127_1779324_6 Helix-turn-helix - - - 0.00000000000000000000000000000000000002642 148.0
TLS3_k127_1779324_8 Glycosyl transferases group 1 - - - 0.000000000000000000000000001867 115.0
TLS3_k127_1802888_0 acyl-CoA dehydrogenase activity - - - 1.029e-198 626.0
TLS3_k127_1802888_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 390.0
TLS3_k127_1802888_2 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 298.0
TLS3_k127_1802888_3 Methyltransferase small domain K00564 - 2.1.1.172 0.0000000000000000000000000000000000000000000000000000000000000000000005812 243.0
TLS3_k127_1802888_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000002203 216.0
TLS3_k127_1802888_5 SpoU rRNA Methylase family K00556 - 2.1.1.34 0.0000000000000000000000000000000000000000000006379 173.0
TLS3_k127_1802888_6 Probable molybdopterin binding domain - - - 0.000000000001523 69.0
TLS3_k127_1802888_7 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000001686 54.0
TLS3_k127_1814055_0 Cytochrome P450 K21119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 418.0
TLS3_k127_1814055_1 acyl-CoA hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000461 215.0
TLS3_k127_1814055_2 SnoaL-like domain - - - 0.0000000000000000000000000000000009149 133.0
TLS3_k127_1818081_0 Evidence 5 No homology to any previously reported sequences K07284 - 3.4.22.70 0.00000000000000000000000000000000000000000000000000000000804 211.0
TLS3_k127_1818081_1 Enoyl-CoA hydratase/isomerase K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.00000000000000000002101 93.0
TLS3_k127_1818081_2 - - - - 0.0000000000000603 81.0
TLS3_k127_1822450_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 524.0
TLS3_k127_1822450_1 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000002615 143.0
TLS3_k127_1822450_2 Participates in both transcription termination and antitermination K02600 - - 0.0001224 52.0
TLS3_k127_1822716_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.369e-253 792.0
TLS3_k127_1822716_1 alpha/beta hydrolase fold K01046 - 3.1.1.3 0.000000000000000000000002771 110.0
TLS3_k127_1825682_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 604.0
TLS3_k127_1825682_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 471.0
TLS3_k127_1825682_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 GO:0000287,GO:0003674,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0034641,GO:0042558,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0046653,GO:0046872,GO:0051186,GO:0071704,GO:1901360,GO:1901564 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000378 247.0
TLS3_k127_1837778_0 Putative modulator of DNA gyrase K03568 - - 1.071e-197 623.0
TLS3_k127_1837778_1 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 542.0
TLS3_k127_1837778_2 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006839 460.0
TLS3_k127_1837778_3 PFAM SAF domain K02279 - - 0.000002407 57.0
TLS3_k127_1843152_0 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000004377 231.0
TLS3_k127_1843152_1 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000002157 241.0
TLS3_k127_185045_0 Belongs to the DegT DnrJ EryC1 family K12452,K13328 - 1.17.1.1,4.2.1.164 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 332.0
TLS3_k127_185045_1 uridine kinase K00876 - 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 307.0
TLS3_k127_185045_2 Thioesterase - - - 0.0000000000000000000000000000000000000000000000000000001737 201.0
TLS3_k127_1856079_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 333.0
TLS3_k127_1856079_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000002677 192.0
TLS3_k127_1857065_0 N-acyl-D-aspartate D-glutamate deacylase - - - 2.823e-210 673.0
TLS3_k127_1857065_1 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 404.0
TLS3_k127_1857065_2 Phosphopantetheine attachment site - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007163 321.0
TLS3_k127_1857065_3 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 288.0
TLS3_k127_1857065_4 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001069 284.0
TLS3_k127_1857065_5 COG0655 Multimeric flavodoxin WrbA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002457 272.0
TLS3_k127_1857065_6 cyclase dehydrase - - - 0.000000000000000000000000000000000000000000000000000000000000000002377 229.0
TLS3_k127_1857065_7 Iron-containing redox enzyme - - - 0.00000000000000000000000000000000006799 146.0
TLS3_k127_1857065_8 sigma factor antagonist activity K04757 - 2.7.11.1 0.0000000000000000000000000006326 125.0
TLS3_k127_1857065_9 sigma factor antagonist activity - - - 0.00000000000000001537 88.0
TLS3_k127_1859113_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 428.0
TLS3_k127_1859113_1 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 329.0
TLS3_k127_1859113_2 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000009056 229.0
TLS3_k127_1859113_3 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000005203 174.0
TLS3_k127_1860207_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 376.0
TLS3_k127_1860207_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 343.0
TLS3_k127_1860207_2 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 290.0
TLS3_k127_1860207_3 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001831 271.0
TLS3_k127_1861483_0 alcohol dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 476.0
TLS3_k127_1861483_1 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 338.0
TLS3_k127_1861483_2 Belongs to the aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 328.0
TLS3_k127_1861483_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006393 243.0
TLS3_k127_1861483_4 acetyltransferase - - - 0.00000000000000000000000000000000000000000003583 164.0
TLS3_k127_1863975_0 von Willebrand factor (vWF) type A domain - - - 1.791e-282 882.0
TLS3_k127_1863975_1 Formiminotransferase domain, N-terminal subdomain K00603 - 2.1.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000245 247.0
TLS3_k127_1863975_2 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000009736 191.0
TLS3_k127_1863975_3 Sigma-70, region 4 K03088 GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.0000000000000000000000000000000000000000000000000005742 189.0
TLS3_k127_1863975_4 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.0000000000000000000000000000000000003086 144.0
TLS3_k127_1863975_5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000001515 78.0
TLS3_k127_1863975_6 protein secretion K03116 - - 0.0000000007394 63.0
TLS3_k127_1864956_0 Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 496.0
TLS3_k127_1864956_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 327.0
TLS3_k127_1864956_2 Epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000008055 195.0
TLS3_k127_1864956_3 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000004176 196.0
TLS3_k127_1864956_4 Peptidase s1 and s6 chymotrypsin hap K08372 - - 0.000000000000000000000000001795 130.0
TLS3_k127_1866531_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 507.0
TLS3_k127_1866531_1 Cell cycle protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 371.0
TLS3_k127_1866531_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 338.0
TLS3_k127_1866531_3 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000702 263.0
TLS3_k127_1866531_4 Protein of unknown function (DUF2662) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002919 239.0
TLS3_k127_1866531_6 Forkhead associated domain - - - 0.0000000000000000000000000000007671 126.0
TLS3_k127_1881633_0 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 540.0
TLS3_k127_1881633_1 Di-haem oxidoreductase, putative peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 434.0
TLS3_k127_1881633_2 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 377.0
TLS3_k127_1881633_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 340.0
TLS3_k127_1881633_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 309.0
TLS3_k127_1881633_5 mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000003247 244.0
TLS3_k127_1881633_6 Evidence 5 No homology to any previously reported sequences K13687 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000000000000000001006 217.0
TLS3_k127_1881633_7 Electron transfer DM13 - - - 0.00000000000000000000000000000000000000000000007093 176.0
TLS3_k127_1881633_8 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000001316 106.0
TLS3_k127_1881633_9 - - - - 0.0000000000000000000001829 101.0
TLS3_k127_1882076_0 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 413.0
TLS3_k127_1882076_1 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 391.0
TLS3_k127_1882076_2 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002163 289.0
TLS3_k127_1882076_3 Maf-like protein K06287 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000001192 202.0
TLS3_k127_1882076_4 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000118 184.0
TLS3_k127_1887391_0 Class II release factor RF3, C-terminal domain K02837 - - 9.937e-249 776.0
TLS3_k127_1887391_1 beta-propeller repeat - - - 1.125e-206 656.0
TLS3_k127_1887391_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 381.0
TLS3_k127_1887391_3 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 368.0
TLS3_k127_1887391_4 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000000007806 152.0
TLS3_k127_1887391_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0001416 53.0
TLS3_k127_1891393_0 GXGXG motif K00265 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 528.0
TLS3_k127_1891393_1 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 404.0
TLS3_k127_1891393_2 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 306.0
TLS3_k127_1891393_3 histone deacetylation - - - 0.0000000000006216 81.0
TLS3_k127_1894221_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 442.0
TLS3_k127_1894221_1 PAC2 family - - - 0.0000000000000000000000000000000000000001039 156.0
TLS3_k127_1904272_0 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003385 265.0
TLS3_k127_1904272_1 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000004629 109.0
TLS3_k127_1906069_0 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007344 373.0
TLS3_k127_1906069_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 316.0
TLS3_k127_1906069_2 PFAM Protein kinase domain - - - 0.000000000000000000000000000000000000000000000002045 191.0
TLS3_k127_1906069_3 DNA glycosylase K03649 - 3.2.2.28 0.0000000000000000000000000000007724 135.0
TLS3_k127_1906069_4 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000002924 98.0
TLS3_k127_1907886_0 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 439.0
TLS3_k127_1907886_1 Ribosome-associated protein Y (PSrp-1) - - - 0.000000000000000000000000000000000000000000000000000001531 200.0
TLS3_k127_1907886_2 E1-E2 ATPase K12952 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 - 0.0000000000000000000000000000000000000000000000000001751 190.0
TLS3_k127_1907886_3 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000001814 134.0
TLS3_k127_1907886_4 Universal stress protein family - - - 0.0000000000000000000000000505 118.0
TLS3_k127_1907886_5 Putative peptidoglycan binding domain - - - 0.0000005584 60.0
TLS3_k127_1941365_0 ERAP1-like C-terminal domain K01256,K08776 - 3.4.11.2 2.044e-231 744.0
TLS3_k127_1941365_1 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 511.0
TLS3_k127_1941365_2 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 358.0
TLS3_k127_1941365_3 COG0524 Sugar kinases, ribokinase family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 362.0
TLS3_k127_1941365_4 membrane protein terC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006435 341.0
TLS3_k127_1941365_5 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000321 111.0
TLS3_k127_1941365_6 Acetyltransferase (GNAT) domain - - - 0.0000000000009751 69.0
TLS3_k127_1941365_8 Universal stress protein - - - 0.00004134 56.0
TLS3_k127_1944832_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 574.0
TLS3_k127_1944832_1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000002372 228.0
TLS3_k127_1954852_0 Aminotransferase K00830,K00839 - 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 488.0
TLS3_k127_1954852_1 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 459.0
TLS3_k127_1954852_10 Protein of unknown function (DUF501) K09009 - - 0.0000000000000000000000000000000000000000000000000475 185.0
TLS3_k127_1954852_11 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.000000000000000000000000000000000005017 145.0
TLS3_k127_1954852_12 - - - - 0.0000000000000000000000000777 112.0
TLS3_k127_1954852_2 Phosphate acyltransferases - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 366.0
TLS3_k127_1954852_3 carbon monoxide dehydrogenase K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001533 271.0
TLS3_k127_1954852_4 Enoyl-CoA hydratase/isomerase K01692 GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000005198 278.0
TLS3_k127_1954852_5 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000006513 271.0
TLS3_k127_1954852_6 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000000000000000004613 252.0
TLS3_k127_1954852_7 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000001489 243.0
TLS3_k127_1954852_8 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000002424 237.0
TLS3_k127_1954852_9 carbon monoxide dehydrogenase subunit G K09386 - - 0.0000000000000000000000000000000000000000000000000000000001001 219.0
TLS3_k127_195849_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 430.0
TLS3_k127_195849_1 Belongs to the glycosyl hydrolase family 6 - - - 0.00000000000000000000000000000000000000000000000000000000000000002927 252.0
TLS3_k127_195849_2 PFAM Haemolysin-type calcium-binding repeat - - - 0.00000000000000000000000000000000000000000000000000004434 213.0
TLS3_k127_195849_3 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000009305 195.0
TLS3_k127_195849_4 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000002978 73.0
TLS3_k127_1961578_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008288 408.0
TLS3_k127_1961578_1 Bacterial extracellular solute-binding protein K10232 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009885 372.0
TLS3_k127_1961578_2 COG1175 ABC-type sugar transport systems permease components K10233 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007337 281.0
TLS3_k127_1970139_0 Binding-protein-dependent transport system inner membrane component K02029,K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001339 261.0
TLS3_k127_1970139_1 ABC transporter, ATP-binding protein K02028,K17076 - 3.6.3.21 0.0000000000000000000000000000000000000000000000001146 196.0
TLS3_k127_1970139_2 Belongs to the bacterial solute-binding protein 3 family K02030 - - 0.0000000000000000000000000000000000000000001355 165.0
TLS3_k127_1975511_0 ABC-type Fe3 transport system permease component K02011,K02063 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 349.0
TLS3_k127_1975511_1 ABC transporter, periplasmic binding protein, thiB subfamily K02064 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 334.0
TLS3_k127_1985131_0 - - - - 0.00000000000000000000000000000000000000000000000002026 194.0
TLS3_k127_1985131_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000163 163.0
TLS3_k127_1985131_2 peptidase M15B and M15C DD-carboxypeptidase VanY endolysin K07260 - 3.4.17.14 0.0000000000000000000000000000000000000002461 153.0
TLS3_k127_2000916_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 3.344e-237 739.0
TLS3_k127_2000916_1 Scavenger mRNA decapping enzyme C-term binding K19710 GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 0.000008375 58.0
TLS3_k127_200717_0 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009025 449.0
TLS3_k127_200717_1 ubiquinone biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 401.0
TLS3_k127_200717_2 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003315 278.0
TLS3_k127_200717_3 Alpha/beta-hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001346 274.0
TLS3_k127_200717_4 DNA alkylation repair - - - 0.000000000000000000000000000000000000000000000000000000006091 213.0
TLS3_k127_200717_5 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000003412 132.0
TLS3_k127_200717_6 Amidohydrolase family - - - 0.00000000889 58.0
TLS3_k127_200942_0 glycyl-radical enzyme activating activity K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 578.0
TLS3_k127_200942_1 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007617 280.0
TLS3_k127_200942_2 pfam ammecr1 K09141 - - 0.0000000000000000000000000000000001471 139.0
TLS3_k127_2013041_0 bifunctional deaminase-reductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004398 226.0
TLS3_k127_2013041_1 GAF domain - - - 0.00000000000000000000000000000000000000000000001309 190.0
TLS3_k127_2013041_2 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000000000000000000000005819 131.0
TLS3_k127_2013041_3 MerR, DNA binding - - - 0.00000000000000000001057 97.0
TLS3_k127_2013041_4 sigma factor antagonist activity K04757 - 2.7.11.1 0.00000000000001968 78.0
TLS3_k127_2024942_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009238 439.0
TLS3_k127_2024942_1 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 416.0
TLS3_k127_2024942_10 Iron-sulphur cluster biosynthesis K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564 - 0.0000000000000000000000000000000000000005081 161.0
TLS3_k127_2024942_11 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000002637 149.0
TLS3_k127_2024942_12 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18958 GO:0001101,GO:0008150,GO:0010033,GO:0033993,GO:0042221,GO:0046677,GO:0050896,GO:0070542,GO:1901700 - 0.0000000000000000000000000001385 125.0
TLS3_k127_2024942_13 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.11 0.00000000000000000000001933 101.0
TLS3_k127_2024942_14 Cytochrome C biogenesis protein - - - 0.00000000000000000000008739 112.0
TLS3_k127_2024942_2 Aldo/keto reductase family - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 368.0
TLS3_k127_2024942_3 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000001397 257.0
TLS3_k127_2024942_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000006607 237.0
TLS3_k127_2024942_5 Replication protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002434 228.0
TLS3_k127_2024942_6 2 iron, 2 sulfur cluster binding K00087,K03518,K07302 - 1.17.1.4,1.2.5.3,1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000006438 226.0
TLS3_k127_2024942_7 SERine Proteinase INhibitors K13963 - - 0.000000000000000000000000000000000000000000000000000000000000002348 235.0
TLS3_k127_2024942_8 Cytochrome c biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000001732 224.0
TLS3_k127_2024942_9 Acyl-ACP thioesterase - - - 0.000000000000000000000000000000000000000000000000723 188.0
TLS3_k127_20267_0 Retinal pigment epithelial membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006629 300.0
TLS3_k127_20267_1 Phospholipase K07001 - - 0.0000000000000000000000000003156 121.0
TLS3_k127_20267_2 Phosphopantetheine attachment site - - - 0.0000000000000000000000000005044 133.0
TLS3_k127_20267_3 protoporphyrinogen oxidase activity K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000008615 115.0
TLS3_k127_2029263_0 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 451.0
TLS3_k127_2029263_1 oxidoreductase - - - 0.0000000000000000000009769 101.0
TLS3_k127_2038253_0 ABC transporter transmembrane region K06147 - - 3.459e-226 722.0
TLS3_k127_2038253_1 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 289.0
TLS3_k127_2038253_2 ABC-type multidrug transport system, ATPase and permease K06147 - - 0.000000000000000000000002859 104.0
TLS3_k127_2040011_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002264 277.0
TLS3_k127_2040011_1 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000005113 158.0
TLS3_k127_2040011_2 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000002474 156.0
TLS3_k127_2041999_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003284 241.0
TLS3_k127_2041999_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000004953 215.0
TLS3_k127_2041999_2 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000005991 163.0
TLS3_k127_2041999_3 Oxidoreductase K13327 - 1.1.1.384 0.0000000003737 72.0
TLS3_k127_2053397_0 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 485.0
TLS3_k127_2053397_1 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 391.0
TLS3_k127_2053397_2 DNA repair protein - - - 0.000000000000000000000000000000000000000000000000002169 190.0
TLS3_k127_2053397_3 - - - - 0.0000000000001163 77.0
TLS3_k127_2053397_4 Major Facilitator Superfamily - - - 0.0000001777 56.0
TLS3_k127_2065519_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000002442 188.0
TLS3_k127_2074616_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K04091 - 1.14.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 534.0
TLS3_k127_2074616_1 Glycosyl transferase 4-like domain K15521 - 2.4.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 442.0
TLS3_k127_2074616_11 - - - - 0.000000000000000000000002561 113.0
TLS3_k127_2074616_12 Mo-molybdopterin cofactor metabolic process K03636,K21142 - 2.8.1.12 0.00000000000000000003779 92.0
TLS3_k127_2074616_2 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 316.0
TLS3_k127_2074616_3 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005998 271.0
TLS3_k127_2074616_4 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000001093 258.0
TLS3_k127_2074616_5 Belongs to the phosphoglycerate mutase family K15640 - - 0.0000000000000000000000000000000000000000000000000000001147 200.0
TLS3_k127_2074616_6 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000001335 190.0
TLS3_k127_2074616_7 Helix-turn-helix XRE-family like proteins - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000001637 164.0
TLS3_k127_2074616_8 Putative bacterial sensory transduction regulator - - - 0.00000000000000000000000000000000000000005199 170.0
TLS3_k127_2074616_9 aldo keto reductase - - - 0.00000000000000000000000000000000000001881 146.0
TLS3_k127_2093541_0 N-acyl-D-aspartate D-glutamate deacylase - - - 1.756e-251 787.0
TLS3_k127_2093541_1 Pfam Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000003015 189.0
TLS3_k127_2116886_0 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 433.0
TLS3_k127_2116886_1 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 362.0
TLS3_k127_2116886_2 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000007949 206.0
TLS3_k127_2116886_3 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000000000000000000001197 192.0
TLS3_k127_2116886_4 N-formylglutamate amidohydrolase - - - 0.0000000001154 64.0
TLS3_k127_2135711_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1057.0
TLS3_k127_2152803_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 441.0
TLS3_k127_2152803_1 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 342.0
TLS3_k127_2152803_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000003039 195.0
TLS3_k127_2156441_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006671 599.0
TLS3_k127_2156441_1 Protein of unknown function (DUF402) K09146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002535 265.0
TLS3_k127_2156441_2 Protein of unknown function (DUF402) K09146 - - 0.00000000000000000000000000001729 123.0
TLS3_k127_2157027_0 acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 524.0
TLS3_k127_2158780_0 FAD binding domain K21401 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016491,GO:0016627,GO:0030312,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 1.3.99.38 2.413e-202 636.0
TLS3_k127_2158780_1 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 509.0
TLS3_k127_2158780_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 488.0
TLS3_k127_2158780_3 Cytochrome c - - - 0.0000000000000000000000000000000000162 143.0
TLS3_k127_2158780_4 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000005729 126.0
TLS3_k127_2159072_0 MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 365.0
TLS3_k127_2159072_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 338.0
TLS3_k127_2159072_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000001841 195.0
TLS3_k127_2159072_3 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.0000000000000000000000000000000000000000007154 164.0
TLS3_k127_2172644_0 Type II secretion system (T2SS), protein F K02653 - - 8.439e-221 689.0
TLS3_k127_2172644_1 type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 520.0
TLS3_k127_2172644_2 Type IV leader peptidase family K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 326.0
TLS3_k127_217643_0 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 500.0
TLS3_k127_217643_1 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 483.0
TLS3_k127_217643_2 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 458.0
TLS3_k127_217643_3 NADP-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000004923 231.0
TLS3_k127_217643_4 KR domain K00059 - 1.1.1.100 0.0000000000002526 83.0
TLS3_k127_2191624_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 467.0
TLS3_k127_2191624_1 DisA bacterial checkpoint controller nucleotide-binding K07067 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 403.0
TLS3_k127_2191624_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00001175 58.0
TLS3_k127_2204949_0 Protein of unknown function (DUF2855) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 314.0
TLS3_k127_2204949_1 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000001293 198.0
TLS3_k127_2204949_2 - - - - 0.000000000000000000000000001021 123.0
TLS3_k127_2212522_0 Monoamine oxidase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 484.0
TLS3_k127_2212522_1 - - - - 0.000000000000000000000000000305 122.0
TLS3_k127_2225152_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 582.0
TLS3_k127_2225152_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009859 286.0
TLS3_k127_2225152_2 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000001784 214.0
TLS3_k127_2225152_3 group 2 family protein - - - 0.000000000000000000000000000000000000000000000000000000175 206.0
TLS3_k127_2225152_4 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000001098 136.0
TLS3_k127_2225528_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 3.255e-206 653.0
TLS3_k127_2225528_1 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0001282 46.0
TLS3_k127_2230739_0 Cytochrome b/b6/petB K03891 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 579.0
TLS3_k127_2230739_1 Rieske [2Fe-2S] domain K03890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 301.0
TLS3_k127_2230739_2 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02351,K07245 - - 0.000000000000000000000000000000000000000000000000000000000000005919 229.0
TLS3_k127_2230739_3 Cytochrome c K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000003284 225.0
TLS3_k127_2230739_4 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000001075 162.0
TLS3_k127_2244445_0 amidohydrolase - - - 7.288e-210 659.0
TLS3_k127_2244445_1 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 497.0
TLS3_k127_2244445_2 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 447.0
TLS3_k127_2244445_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 381.0
TLS3_k127_2244445_4 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 317.0
TLS3_k127_226960_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 446.0
TLS3_k127_226960_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003428 287.0
TLS3_k127_2270830_0 Sodium/hydrogen exchanger family K11105 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 477.0
TLS3_k127_2270830_1 Universal stress protein family - - - 0.0000000000000000000000000006125 118.0
TLS3_k127_2270830_2 - - - - 0.00000000000000000000000008019 116.0
TLS3_k127_2270830_3 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000003223 91.0
TLS3_k127_2270830_4 regulatory, ligand-binding protein related to C-terminal domains of K channels K07228 - - 0.00000001183 63.0
TLS3_k127_2271200_0 Protein of unknown function (DUF933) K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 375.0
TLS3_k127_2271200_1 Domain of Unknown Function (DUF1206) - - - 0.000000000000000000000000000000000000000000000002153 183.0
TLS3_k127_2271200_2 3-methyladenine DNA glycosylase - - - 0.00000000000000000000000000000000001327 137.0
TLS3_k127_2274954_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 497.0
TLS3_k127_2274954_1 peptidase A24A prepilin type IV K02654 - 3.4.23.43 0.00000000000000000000001879 108.0
TLS3_k127_2274954_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000265 97.0
TLS3_k127_2274954_3 peptidyl-tyrosine sulfation - - - 0.00000000003432 75.0
TLS3_k127_2353559_0 Penicillin amidase K07116 GO:0005575,GO:0005576 3.5.1.97 4.148e-259 822.0
TLS3_k127_2353559_1 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 491.0
TLS3_k127_2353559_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000706 395.0
TLS3_k127_2353559_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 359.0
TLS3_k127_2353559_4 FCD - - - 0.000000000000000000000000000000000000000000000000000000002219 211.0
TLS3_k127_2353559_5 Protein of unknown function (DUF3225) - - - 0.0000000000000000000000000000000008696 134.0
TLS3_k127_2356654_0 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 527.0
TLS3_k127_2356654_1 cytochrome p450 - GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 366.0
TLS3_k127_2356654_2 Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004151 248.0
TLS3_k127_2356654_3 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000003201 175.0
TLS3_k127_2356654_4 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000000003233 99.0
TLS3_k127_2356654_5 Activator of Hsp90 ATPase 1 family - - - 0.000000000000000005235 84.0
TLS3_k127_2356654_6 Dehydrogenase - - - 0.00000000000000007174 89.0
TLS3_k127_2358167_0 STAS domain K03321 - - 1.95e-239 752.0
TLS3_k127_2358167_1 PFAM Polyphosphate kinase 2 K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008246 409.0
TLS3_k127_2358167_2 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000000000000000000000008247 213.0
TLS3_k127_2358167_3 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000164 198.0
TLS3_k127_2358167_4 Membrane - - - 0.00000000000000000000000000000000000000000000000000046 187.0
TLS3_k127_2358167_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000005317 78.0
TLS3_k127_2360990_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0008150,GO:0040007 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 419.0
TLS3_k127_2360990_1 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 414.0
TLS3_k127_2360990_2 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008362 411.0
TLS3_k127_2360990_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 362.0
TLS3_k127_2360990_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 328.0
TLS3_k127_2360990_5 Belongs to the MraZ family K03925 - - 0.00000000000000000000000005248 113.0
TLS3_k127_2367457_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 486.0
TLS3_k127_2367457_1 Domain of unknown function (DUF4439) - - - 0.00006137 54.0
TLS3_k127_2376211_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 1.514e-312 983.0
TLS3_k127_2376211_1 beta-mannosidase K01192,K15855 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0071704,GO:1901575 3.2.1.165,3.2.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 625.0
TLS3_k127_2376211_2 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 452.0
TLS3_k127_2376211_3 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003434 263.0
TLS3_k127_2376211_4 PFAM ATP-binding region, ATPase domain protein domain protein - - - 0.00000000611 67.0
TLS3_k127_2435657_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 395.0
TLS3_k127_2435657_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000005171 85.0
TLS3_k127_244102_0 Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 302.0
TLS3_k127_244102_1 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000004306 191.0
TLS3_k127_244102_2 Thioesterase - - - 0.00000000000000000000000000000008316 129.0
TLS3_k127_244102_3 Domain of unknown function (DUF4185) - - - 0.0005317 53.0
TLS3_k127_2445608_0 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000002736 220.0
TLS3_k127_2445608_1 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000746 165.0
TLS3_k127_2445608_2 Sulfotransferase family - - - 0.000000000000000000000000000000000000001515 156.0
TLS3_k127_2445608_3 Glycosyltransferase like family 2 K16870 - 2.4.1.289 0.0008535 47.0
TLS3_k127_2452013_0 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 392.0
TLS3_k127_2452013_1 Predicted membrane protein (DUF2142) - - - 0.0000000000000000000000000000000004173 145.0
TLS3_k127_2452013_2 functions in conversion of succinate to propionate K01847 - 5.4.99.2 0.0000000239 55.0
TLS3_k127_246641_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 7e-201 632.0
TLS3_k127_246641_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000009718 189.0
TLS3_k127_2467148_0 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 355.0
TLS3_k127_2467148_1 Sulfotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 293.0
TLS3_k127_2467148_2 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001486 270.0
TLS3_k127_2467148_3 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000005189 173.0
TLS3_k127_2467148_4 arsR family - - - 0.000000000000000000000000000000000001254 139.0
TLS3_k127_2467148_5 hydrolase activity, acting on ester bonds K07017 - - 0.00000000000000000000000000001903 128.0
TLS3_k127_2467148_6 Beta-lactamase enzyme family K01467,K17836 - 3.5.2.6 0.00000000003357 74.0
TLS3_k127_2476206_0 Alcohol dehydrogenase GroES-associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 580.0
TLS3_k127_2476206_1 Glutaminase K01425 - 3.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 452.0
TLS3_k127_2476206_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008511 365.0
TLS3_k127_2479312_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 347.0
TLS3_k127_2479312_1 Phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.0000000000000000003766 100.0
TLS3_k127_2479312_2 - - - - 0.000000000000000008765 94.0
TLS3_k127_2479312_3 His Kinase A (phosphoacceptor) domain K07653 - 2.7.13.3 0.0000000000001816 70.0
TLS3_k127_2479312_4 PhoD-like phosphatase K01113 - 3.1.3.1 0.0000001681 61.0
TLS3_k127_2506695_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K08299 - 4.2.1.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004038 296.0
TLS3_k127_2506695_1 Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002661 261.0
TLS3_k127_2506695_2 enoyl-CoA hydratase K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.000000000000000000000000000000000000000000000001239 184.0
TLS3_k127_2506695_3 Protein of unknown function (DUF1211) - - - 0.00000000000000000007842 97.0
TLS3_k127_2520944_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 527.0
TLS3_k127_2520944_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000003596 124.0
TLS3_k127_2525739_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003278 268.0
TLS3_k127_2536729_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 601.0
TLS3_k127_2536729_1 ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 509.0
TLS3_k127_2536729_2 Belongs to the P(II) protein family K04751 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000003576 177.0
TLS3_k127_2554246_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 596.0
TLS3_k127_2554246_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001866 287.0
TLS3_k127_257263_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1015.0
TLS3_k127_257263_1 PFAM AMP-dependent synthetase and ligase K00666,K01909 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008922,GO:0009058,GO:0009987,GO:0015645,GO:0016020,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016874,GO:0016877,GO:0016878,GO:0017076,GO:0019752,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0051704,GO:0070566,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 6.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002421 278.0
TLS3_k127_2582074_0 Zinc-binding dehydrogenase K17829 - 1.3.1.86 5.416e-227 722.0
TLS3_k127_2582074_1 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007746 586.0
TLS3_k127_2582074_10 - - - - 0.00009429 51.0
TLS3_k127_2582074_2 Thiolase, C-terminal domain K00626 GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044403,GO:0044419,GO:0044464,GO:0046395,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:0075136,GO:1901575 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 541.0
TLS3_k127_2582074_3 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 454.0
TLS3_k127_2582074_4 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007856 359.0
TLS3_k127_2582074_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006949 317.0
TLS3_k127_2582074_6 domain protein K14194 - - 0.00000000000000000000000000000000000000000000000000000000005435 224.0
TLS3_k127_2582074_7 Glyoxalase-like domain K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000000000002661 199.0
TLS3_k127_2582074_8 - - - - 0.00000000000000000000000004409 126.0
TLS3_k127_2582074_9 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000001275 76.0
TLS3_k127_2582559_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 402.0
TLS3_k127_2582559_1 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 374.0
TLS3_k127_2582559_2 Inositol monophosphatase K01092 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000005103 243.0
TLS3_k127_259178_0 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 302.0
TLS3_k127_259178_1 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000007086 197.0
TLS3_k127_259178_2 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000001026 146.0
TLS3_k127_259178_3 Ribosomal L27 protein K02899 - - 0.000000000000000000000000000000002619 130.0
TLS3_k127_2602095_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 334.0
TLS3_k127_2602095_1 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001679 243.0
TLS3_k127_2602095_2 PFAM Rubrerythrin - - - 0.000000000000000000007858 91.0
TLS3_k127_2602095_3 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.0000000000000000004199 95.0
TLS3_k127_2605732_0 Nitronate monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 571.0
TLS3_k127_2605732_1 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 415.0
TLS3_k127_2605732_3 GCN5-related N-acetyl-transferase K06975 - - 0.00009764 46.0
TLS3_k127_2617091_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 337.0
TLS3_k127_2617091_1 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001181 284.0
TLS3_k127_2617091_2 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000002294 162.0
TLS3_k127_2617091_3 Belongs to the FGGY kinase family K00854 - 2.7.1.17 0.0000000000000000000758 90.0
TLS3_k127_2625743_0 ACT domain K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 525.0
TLS3_k127_2625743_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004182 270.0
TLS3_k127_2630943_0 IMP dehydrogenase / GMP reductase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 462.0
TLS3_k127_2630943_1 Coenzyme A transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005633 276.0
TLS3_k127_2635201_0 Domain of unknown function (DUF3367) - - - 0.0000000000000000000000000000000000000000000000000001741 201.0
TLS3_k127_2635201_1 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000004623 190.0
TLS3_k127_2635201_2 COG3209 Rhs family protein - - - 0.000000000000516 82.0
TLS3_k127_2639098_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520,K19820 - 1.2.5.3,1.5.99.4 0.0 1028.0
TLS3_k127_2639098_1 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 582.0
TLS3_k127_2639098_2 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 380.0
TLS3_k127_2639098_3 2Fe-2S -binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000009917 246.0
TLS3_k127_2639098_4 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000005739 242.0
TLS3_k127_2639098_5 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000128 209.0
TLS3_k127_2639098_6 NAD(P)H-dependent FMN reductase K00299 - 1.5.1.38 0.000000000000000000000000000000000000000001623 162.0
TLS3_k127_2639098_7 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000007225 152.0
TLS3_k127_2639098_8 Luciferase-like monooxygenase - - - 0.0002839 44.0
TLS3_k127_2639821_0 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 327.0
TLS3_k127_2639821_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002325 281.0
TLS3_k127_2639821_2 ATP- GTP-binding protein K06945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007909 260.0
TLS3_k127_2639821_3 Roadblock/LC7 domain K07131 - - 0.000000000000000000000000000000000000000001048 160.0
TLS3_k127_2639821_4 Transcriptional regulator - - - 0.0000000000000000000000004479 107.0
TLS3_k127_2640308_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 642.0
TLS3_k127_2640308_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 608.0
TLS3_k127_2640308_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 314.0
TLS3_k127_2640308_3 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004439 268.0
TLS3_k127_2640308_4 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000001187 99.0
TLS3_k127_2640308_5 PFAM N-acetylmuramoyl-L-alanine amidase, family 2 - - - 0.00000000002214 77.0
TLS3_k127_264664_0 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006954 281.0
TLS3_k127_2650422_0 Zn peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001322 268.0
TLS3_k127_2650422_1 Domain of unknown function (DUF2017) - - - 0.00000000000000001207 86.0
TLS3_k127_2654727_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1189.0
TLS3_k127_2654727_1 VirC1 protein K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003348 268.0
TLS3_k127_2654727_2 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000001156 201.0
TLS3_k127_2654727_3 - - - - 0.000000000000000000000000000009833 120.0
TLS3_k127_2654727_4 - - - - 0.00001333 56.0
TLS3_k127_2660010_0 CoA binding domain - - - 8.895e-204 647.0
TLS3_k127_2660010_1 PP-loop family K21947 - 2.8.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 448.0
TLS3_k127_2660010_10 transcriptional regulator K09017 - - 0.000000000414 61.0
TLS3_k127_2660010_11 Colicin V production protein - - - 0.000000009466 68.0
TLS3_k127_2660010_12 Domain of unknown function (DUF4190) - - - 0.0000002024 64.0
TLS3_k127_2660010_2 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 350.0
TLS3_k127_2660010_3 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009753 296.0
TLS3_k127_2660010_4 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003633 247.0
TLS3_k127_2660010_5 beta-N-acetylglucosaminidase K01197 - 3.2.1.35 0.000000000000000000000000000000000000000000000000000001885 207.0
TLS3_k127_2660010_6 Peptidase S16, lon domain protein K01338,K07157 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000003834 194.0
TLS3_k127_2660010_7 ferredoxin K05337 - - 0.0000000000000000000000000000000006105 137.0
TLS3_k127_2660010_8 ThiS family K03154 - - 0.000000000000001446 78.0
TLS3_k127_2660010_9 - - - - 0.00000000000002618 78.0
TLS3_k127_2662127_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 649.0
TLS3_k127_2662127_1 RHS Repeat - - - 0.000000000000000000000000000000000000003924 166.0
TLS3_k127_2665181_0 protein conserved in bacteria K09781 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 393.0
TLS3_k127_2665181_1 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000316 269.0
TLS3_k127_2665181_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.17.4.1 0.000000000005658 66.0
TLS3_k127_2666870_0 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 490.0
TLS3_k127_2666870_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.000000000000000000000000001735 112.0
TLS3_k127_2666870_2 long-chain fatty acid transport protein - - - 0.0000000006756 61.0
TLS3_k127_2671165_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.4.4.2 0.0 1294.0
TLS3_k127_2671165_1 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009795 452.0
TLS3_k127_2671165_2 Monooxygenase K14733 - 1.14.13.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 361.0
TLS3_k127_2676230_0 ACT domain K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009114 545.0
TLS3_k127_2676230_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 334.0
TLS3_k127_2676563_0 Right handed beta helix region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004796 282.0
TLS3_k127_2676563_1 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000008683 253.0
TLS3_k127_2676563_2 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000004404 105.0
TLS3_k127_2676563_4 PFAM blue (type 1) copper domain protein - - - 0.000000000001368 78.0
TLS3_k127_2688741_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 432.0
TLS3_k127_2688741_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 360.0
TLS3_k127_2689964_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 425.0
TLS3_k127_2689964_1 NUDIX domain - - - 0.00000000000002943 76.0
TLS3_k127_2695492_0 dioxygenase K11159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 379.0
TLS3_k127_2695492_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000001487 148.0
TLS3_k127_2697458_0 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 340.0
TLS3_k127_2697458_1 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000901 208.0
TLS3_k127_2697458_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000006619 112.0
TLS3_k127_2699151_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 501.0
TLS3_k127_2714114_0 ABC transporter, ATP-binding protein K16786,K16787 - - 1.759e-209 674.0
TLS3_k127_2714114_1 cobalt transport K16785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 347.0
TLS3_k127_2714114_2 ABC transporter (Permease) K16927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 301.0
TLS3_k127_2714114_3 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 304.0
TLS3_k127_2714114_4 Fructosamine kinase - GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 - 0.00000000000000000000000000000000000000000000000000000000000001528 224.0
TLS3_k127_2714114_5 Low molecular weight phosphatase family K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000147 173.0
TLS3_k127_2714114_7 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00058 - 1.1.1.26,1.1.1.399,1.1.1.95 0.00000000000000002124 85.0
TLS3_k127_2722613_0 Class-II DAHP synthetase family K01626 - 2.5.1.54 1.329e-211 664.0
TLS3_k127_2722613_1 Nitrite and sulphite reductase 4Fe-4S domain K00362,K00366,K00381,K00392 - 1.7.1.15,1.7.7.1,1.8.1.2,1.8.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007783 473.0
TLS3_k127_2722613_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 366.0
TLS3_k127_2722613_3 Reduction of activated sulfate into sulfite K00390 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004604,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016667,GO:0016671,GO:0019344,GO:0019752,GO:0040007,GO:0043436,GO:0043866,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000002532 189.0
TLS3_k127_2727450_0 cytochrome p450 K16046 - 1.14.13.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 448.0
TLS3_k127_2727450_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 370.0
TLS3_k127_2727450_2 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000006961 161.0
TLS3_k127_2727450_3 Single-stranded DNA-binding protein K03111 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000001964 153.0
TLS3_k127_2727450_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000003325 142.0
TLS3_k127_2727450_5 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000003174 106.0
TLS3_k127_2729172_0 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000441 285.0
TLS3_k127_2729172_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000001091 254.0
TLS3_k127_2729172_2 May be involved in recombinational repair of damaged DNA K03631 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000001003 118.0
TLS3_k127_2729172_3 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000001817 106.0
TLS3_k127_2730651_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.0 1605.0
TLS3_k127_2730651_1 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 292.0
TLS3_k127_2731191_0 F420-dependent oxidoreductase, MSMEG_3544 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 347.0
TLS3_k127_2731191_1 Short-chain dehydrogenase reductase sdr K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 296.0
TLS3_k127_2731191_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000004444 180.0
TLS3_k127_2732332_0 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 372.0
TLS3_k127_2732332_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 308.0
TLS3_k127_2732332_2 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.000000000000000000000000000000000000000000000000000002113 203.0
TLS3_k127_2732332_3 pyridoxamine 5-phosphate - - - 0.00000000000000000000000000000000000000000000000008374 179.0
TLS3_k127_2733301_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000006021 197.0
TLS3_k127_2741407_0 ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000061 261.0
TLS3_k127_2741407_1 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000000000000001486 146.0
TLS3_k127_2741407_2 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000001209 143.0
TLS3_k127_2741407_3 4Fe-4S dicluster domain - - - 0.000007264 52.0
TLS3_k127_2744375_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 614.0
TLS3_k127_2744375_1 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 456.0
TLS3_k127_2744375_2 Enoyl-CoA hydratase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009255 374.0
TLS3_k127_2744375_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 364.0
TLS3_k127_2744375_4 PFAM NAD dependent epimerase dehydratase family K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000001076 183.0
TLS3_k127_2744375_5 PFAM DsrC family protein K11179 - - 0.0000000000000000000000000002829 117.0
TLS3_k127_2744375_6 Oxidoreductase molybdopterin binding domain K00387 - 1.8.3.1 0.000000006668 57.0
TLS3_k127_2744965_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 364.0
TLS3_k127_2744965_1 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004542 249.0
TLS3_k127_2750102_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00122 - 1.17.1.9 7.66e-269 848.0
TLS3_k127_2750102_1 PFAM Sulfotransferase K01014 - 2.8.2.1 0.000000000000001616 78.0
TLS3_k127_2754773_0 Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004412 259.0
TLS3_k127_2754773_1 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000811 216.0
TLS3_k127_2754773_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000003569 115.0
TLS3_k127_2771243_0 ABC-type dipeptide oligopeptide nickel transport system, permease component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 400.0
TLS3_k127_2771243_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 370.0
TLS3_k127_2771243_2 ABC-type dipeptide oligopeptide nickel transport K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 358.0
TLS3_k127_2774080_0 Pfam Sodium hydrogen exchanger K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 381.0
TLS3_k127_2774080_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000131 287.0
TLS3_k127_2774080_2 - - - - 0.00000000000000000000000000000000000000000000000000000004594 214.0
TLS3_k127_2774080_3 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000000000000002607 169.0
TLS3_k127_2774080_4 domain, Protein K07228 - - 0.000000000000000000000000000000000000000004305 161.0
TLS3_k127_2774080_5 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000005024 132.0
TLS3_k127_2774080_6 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K13940 GO:0008150,GO:0040007 1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8 0.00000000000000000000000000009724 121.0
TLS3_k127_2776246_0 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 355.0
TLS3_k127_2776246_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 300.0
TLS3_k127_2776246_2 unsaturated fatty acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000105 310.0
TLS3_k127_2776246_3 Phenylacetic acid-responsive transcriptional repressor K02616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004376 248.0
TLS3_k127_2776246_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000001969 176.0
TLS3_k127_2776246_5 Thioesterase superfamily - - - 0.000000000000000000000000000002293 127.0
TLS3_k127_2776246_6 protein conserved in bacteria K09984 - - 0.000000000000003407 83.0
TLS3_k127_2787300_0 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 295.0
TLS3_k127_2787300_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000009362 230.0
TLS3_k127_2787300_2 Fructose-1,6-bisphosphatase K02446 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.00000000000005343 72.0
TLS3_k127_2787300_3 general secretion pathway protein K02457,K02458,K02650,K10926,K10930,K10931 GO:0003674,GO:0005198,GO:0005575,GO:0005623,GO:0008150,GO:0009289,GO:0009405,GO:0009987,GO:0016043,GO:0030030,GO:0042995,GO:0044419,GO:0044464,GO:0051704,GO:0071840 - 0.0000003311 63.0
TLS3_k127_2787300_4 Domain of unknown function (DUF4328) - - - 0.00002202 57.0
TLS3_k127_2797592_0 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 495.0
TLS3_k127_2797592_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K14441 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 429.0
TLS3_k127_2797592_2 CDP-alcohol phosphatidyltransferase K00995,K08744 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000002084 171.0
TLS3_k127_2801075_0 Flavoprotein involved in K transport K14520 - 1.14.13.84 1.599e-269 844.0
TLS3_k127_2801075_1 AMP-binding enzyme C-terminal domain - - - 9.998e-231 747.0
TLS3_k127_2801075_2 dUTP biosynthetic process K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008617 496.0
TLS3_k127_2801075_3 Pirin C-terminal cupin domain K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000001871 230.0
TLS3_k127_2801075_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000004235 203.0
TLS3_k127_2802058_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 395.0
TLS3_k127_2802058_1 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 344.0
TLS3_k127_2802058_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009261 310.0
TLS3_k127_2802058_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000002857 205.0
TLS3_k127_2802058_4 proton-transporting ATP synthase activity, rotational mechanism K02114 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000276 106.0
TLS3_k127_2803272_0 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 316.0
TLS3_k127_2803272_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000001185 222.0
TLS3_k127_2803272_2 Acetoacetate decarboxylase (ADC) - - - 0.0000000000000000000000000000000000000000018 165.0
TLS3_k127_2803272_3 Beta-propeller repeat - - - 0.0000000000000000000008419 108.0
TLS3_k127_2803272_5 Belongs to the glycosyl hydrolase 32 family K01212,K03332 - 3.2.1.65,3.2.1.80 0.0000002594 63.0
TLS3_k127_2812403_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00341 - 1.6.5.3 7.757e-233 741.0
TLS3_k127_2812403_1 Belongs to the complex I 49 kDa subunit family K00333 - 1.6.5.3 6.267e-211 672.0
TLS3_k127_2812403_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00342 - 1.6.5.3 2.914e-200 632.0
TLS3_k127_2812403_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 396.0
TLS3_k127_2812403_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003541 274.0
TLS3_k127_2812403_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000001441 218.0
TLS3_k127_2812403_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000005635 217.0
TLS3_k127_2812403_7 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.00000000000000000000000000000000000000009253 158.0
TLS3_k127_2812403_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000003987 139.0
TLS3_k127_2814993_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 472.0
TLS3_k127_2814993_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004224 270.0
TLS3_k127_2814993_2 Nucleotidyl transferase K00966,K00992 - 2.7.7.13,2.7.7.99 0.0000000000000000000000000000000000000000000000000000003867 203.0
TLS3_k127_2814993_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000002234 85.0
TLS3_k127_28154_0 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 414.0
TLS3_k127_28154_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009791 362.0
TLS3_k127_28154_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 302.0
TLS3_k127_28154_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000522 89.0
TLS3_k127_28154_4 Lipase (class 2) - - - 0.00008575 52.0
TLS3_k127_2815654_0 HELICc2 K03722 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 542.0
TLS3_k127_2815654_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 332.0
TLS3_k127_2826725_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 5.041e-221 694.0
TLS3_k127_2826725_1 PFAM SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 326.0
TLS3_k127_2826725_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001301 287.0
TLS3_k127_2826725_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000003144 175.0
TLS3_k127_2826725_4 Phosphoribosylglycinamide synthetase, C domain K01945,K11788 GO:0008150,GO:0040007 6.3.3.1,6.3.4.13 0.000000000000000000000000000001313 124.0
TLS3_k127_2826725_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01923,K01952 - 6.3.2.6,6.3.5.3 0.0000000000000000000000004194 115.0
TLS3_k127_2836220_0 Fibronectin type III domain K12567 - 2.7.11.1 0.0000000000000000000000000000000000000007917 171.0
TLS3_k127_2846569_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001017 226.0
TLS3_k127_2846569_1 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000001293 210.0
TLS3_k127_2846569_2 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.0000000000000000000000000000000000000001355 169.0
TLS3_k127_2846784_0 PFAM Glycoside hydrolase, family 38 K01191,K15524 - 3.2.1.170,3.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008909 549.0
TLS3_k127_2846784_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000001916 215.0
TLS3_k127_2846784_2 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000005267 177.0
TLS3_k127_2846784_3 GYD domain - - - 0.00000000000000000000000000001197 120.0
TLS3_k127_2848338_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 421.0
TLS3_k127_2848338_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000002717 200.0
TLS3_k127_2854277_0 glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 368.0
TLS3_k127_2861314_0 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 315.0
TLS3_k127_2861314_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000598 156.0
TLS3_k127_2861314_2 Metal-sensitive transcriptional repressor - - - 0.00000000000000000000000000000000001495 138.0
TLS3_k127_28625_0 Acetyl-CoA acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 533.0
TLS3_k127_28625_1 Acyl-CoA dehydrogenase, middle domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 486.0
TLS3_k127_28625_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000005735 226.0
TLS3_k127_28625_3 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.00000000000000000000000000000000000000000001668 165.0
TLS3_k127_28625_4 6-phosphogluconate dehydrogenase (Decarboxylating) K00033 - 1.1.1.343,1.1.1.44 0.0003133 43.0
TLS3_k127_2864145_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1161.0
TLS3_k127_2864145_1 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 347.0
TLS3_k127_2864145_2 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000005542 261.0
TLS3_k127_2864145_3 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.0000001318 55.0
TLS3_k127_2873959_0 Dienelactone hydrolase family - - - 9.278e-220 704.0
TLS3_k127_2873959_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 2.039e-213 677.0
TLS3_k127_2873959_2 Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000004679 144.0
TLS3_k127_2873959_3 SCO1 SenC K07152 - - 0.00000000000000000000000000000000000969 140.0
TLS3_k127_2873959_4 PFAM blue (type 1) copper domain protein - - - 0.000000000000006221 84.0
TLS3_k127_2875618_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 419.0
TLS3_k127_2875618_1 helicase superfamily c-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 413.0
TLS3_k127_2875618_2 Phospholipase_D-nuclease N-terminal - - - 0.000000000000000000000001301 109.0
TLS3_k127_2875618_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006355,GO:0006725,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010106,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019725,GO:0030003,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0040007,GO:0042262,GO:0042592,GO:0042594,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046916,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0060255,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090143,GO:0090304,GO:0097100,GO:0097159,GO:0098771,GO:0140110,GO:1901360,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000001979 96.0
TLS3_k127_2876584_0 Sulfatase - - - 8.421e-238 761.0
TLS3_k127_2876584_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 353.0
TLS3_k127_2877882_0 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 485.0
TLS3_k127_2877882_1 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 439.0
TLS3_k127_2877882_2 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009014 407.0
TLS3_k127_2877882_3 NADPH quinone K00344 - 1.6.5.5 0.00000000000000000000000000000001085 129.0
TLS3_k127_2877882_4 Glyoxalase-like domain - - - 0.0000000000003104 71.0
TLS3_k127_2881309_0 ABC transporter substrate-binding protein PnrA-like K02058,K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 510.0
TLS3_k127_2881309_1 Isochorismatase family K09020 - 3.5.1.110 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 402.0
TLS3_k127_2881309_2 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000706 270.0
TLS3_k127_2881309_3 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000008502 277.0
TLS3_k127_2881309_4 Isochorismatase family - - - 0.00000000000000000000000000361 120.0
TLS3_k127_2881721_0 Protein of unknown function (DUF1214) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 410.0
TLS3_k127_2881721_1 Protein of unknown function (DUF4230) - - - 0.000000000000000000000000000000000000000009982 162.0
TLS3_k127_2881721_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 GO:0003674,GO:0003824,GO:0004016,GO:0005488,GO:0005504,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0031406,GO:0033293,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046058,GO:0046390,GO:0046483,GO:0052652,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.1 0.00000000000000000000006388 109.0
TLS3_k127_2892974_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 4.928e-290 917.0
TLS3_k127_2892974_1 Ammonium Transporter Family K03320 - - 1.479e-195 623.0
TLS3_k127_2892974_2 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000002843 194.0
TLS3_k127_2902624_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 577.0
TLS3_k127_2902624_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000854 372.0
TLS3_k127_2902624_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000005685 150.0
TLS3_k127_2912098_0 Major facilitator Superfamily K08369 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 333.0
TLS3_k127_2912098_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 312.0
TLS3_k127_2912098_2 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000004686 175.0
TLS3_k127_2930530_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008142 327.0
TLS3_k127_2930530_1 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000005865 188.0
TLS3_k127_2930530_2 Acyl-CoA thioesterase K10805 - - 0.000000003523 57.0
TLS3_k127_293344_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 434.0
TLS3_k127_293344_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.3.4.2 0.0000000000000000000000000000000000000000319 164.0
TLS3_k127_293520_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00341 - 1.6.5.3 1.756e-214 685.0
TLS3_k127_293520_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 514.0
TLS3_k127_293520_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K12143 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 328.0
TLS3_k127_293520_3 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944 1.6.5.3 0.00000000000000000000000000000000001584 145.0
TLS3_k127_293520_4 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000002513 134.0
TLS3_k127_293520_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000003498 125.0
TLS3_k127_293520_6 Protein synonym NADH dehydrogenase I subunit M K00342 - 1.6.5.3 0.00000001133 61.0
TLS3_k127_2943997_0 FAD dependent oxidoreductase - - - 4.511e-214 679.0
TLS3_k127_2943997_1 Activator of Hsp90 ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000007108 220.0
TLS3_k127_2943997_2 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000001642 203.0
TLS3_k127_2943997_3 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000004257 191.0
TLS3_k127_2943997_4 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000002384 186.0
TLS3_k127_2943997_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000002851 155.0
TLS3_k127_2943997_6 ParB-like nuclease domain - - - 0.00000000000000001823 88.0
TLS3_k127_2956602_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 412.0
TLS3_k127_2956602_1 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009964 387.0
TLS3_k127_2956602_2 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 340.0
TLS3_k127_2956602_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000005528 174.0
TLS3_k127_2956602_4 pyridoxamine 5-phosphate - - - 0.00000000000000000000000000000000000000001857 158.0
TLS3_k127_2956602_5 TOBE domain - - - 0.0000000000000000000000000000000000002136 145.0
TLS3_k127_2956602_6 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000007687 137.0
TLS3_k127_2956602_7 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000009154 132.0
TLS3_k127_2956602_8 molybdate-binding protein K02020 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 - 0.00000000000000000000002039 111.0
TLS3_k127_2957159_0 Sulfatase K01130 - 3.1.6.1 1.194e-228 724.0
TLS3_k127_2957159_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 632.0
TLS3_k127_2957159_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 358.0
TLS3_k127_2957159_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007567 344.0
TLS3_k127_2957159_4 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 289.0
TLS3_k127_2957159_5 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001214 274.0
TLS3_k127_2957159_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002096 276.0
TLS3_k127_2957159_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001514 266.0
TLS3_k127_2966339_0 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 412.0
TLS3_k127_2966339_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000003983 110.0
TLS3_k127_2966339_2 diguanylate cyclase - - - 0.00001315 51.0
TLS3_k127_2968768_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000899 334.0
TLS3_k127_2968768_1 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000003499 245.0
TLS3_k127_2984695_0 Acyl-CoA dehydrogenase, middle domain - - - 2.22e-198 625.0
TLS3_k127_2984695_1 enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 417.0
TLS3_k127_2984695_2 Enoyl-CoA hydratase carnithine racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 345.0
TLS3_k127_2984695_3 AMP-binding enzyme C-terminal domain - - - 0.000000000000000009698 90.0
TLS3_k127_2990323_0 Sulfatase - - - 1.966e-205 651.0
TLS3_k127_2990323_1 potassium ion transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 555.0
TLS3_k127_2990323_10 helix_turn_helix, cAMP Regulatory protein - - - 0.0000000000000001118 91.0
TLS3_k127_2990323_2 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 407.0
TLS3_k127_2990323_3 GlcNAc-PI de-N-acetylase K18455 GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010126,GO:0010127,GO:0016137,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0071704,GO:0098754,GO:1901135,GO:1901657 3.5.1.115 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 331.0
TLS3_k127_2990323_4 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000001518 185.0
TLS3_k127_2990323_5 helix_turn_helix, cAMP Regulatory protein - - - 0.00000000000000000000000000000000006092 142.0
TLS3_k127_2990323_6 AAA ATPase domain - - - 0.00000000000000000000000000000002491 141.0
TLS3_k127_2990323_7 AAA ATPase domain - - - 0.00000000000000000000000000000263 140.0
TLS3_k127_2990323_8 Phosphatidylethanolamine-binding protein K06910 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000002616 107.0
TLS3_k127_2990323_9 cellular response to DNA damage stimulus K07340 - - 0.00000000000000000005315 96.0
TLS3_k127_2994994_0 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 403.0
TLS3_k127_2994994_1 Tetratricopeptide repeat K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006661 289.0
TLS3_k127_2994994_2 PAC2 family - - - 0.0000000000000000058 89.0
TLS3_k127_3010230_0 Aminotransferase class-V K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 335.0
TLS3_k127_3010230_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000003313 166.0
TLS3_k127_3012556_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 377.0
TLS3_k127_3012556_1 DUF218 domain - - - 0.0000000000000000000000000000000000000000000001387 181.0
TLS3_k127_3023757_0 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 529.0
TLS3_k127_3026862_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 326.0
TLS3_k127_3026862_1 Dihydrodipicolinate reductase, N-terminus - - - 0.00000000000000000000000000002103 119.0
TLS3_k127_3029252_0 PFAM Aminotransferase class I and II K00812,K14267 - 2.6.1.1,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 444.0
TLS3_k127_3029252_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 441.0
TLS3_k127_3049707_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 478.0
TLS3_k127_3049707_1 Short-chain dehydrogenase reductase sdr K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 390.0
TLS3_k127_3049707_2 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 364.0
TLS3_k127_3049707_3 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006815 240.0
TLS3_k127_3049707_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000002873 173.0
TLS3_k127_3051091_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 591.0
TLS3_k127_3051091_1 Peptidase family M50 - - - 0.0000000000000000000000000000004421 134.0
TLS3_k127_305758_0 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 398.0
TLS3_k127_305758_1 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.00000000000000000000000000000003582 134.0
TLS3_k127_305758_2 regulatory protein, FmdB family - - - 0.0000000000000000000000001505 109.0
TLS3_k127_3078681_0 PFAM acyl-CoA dehydrogenase domain protein - - - 8.099e-226 705.0
TLS3_k127_3078681_1 zinc transporter K07238 - - 0.0000000000000000000000000000000000000000000000000000000000004576 218.0
TLS3_k127_3078681_2 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000003257 200.0
TLS3_k127_3078681_3 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000001769 190.0
TLS3_k127_3078681_4 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000000000000000000000000000005218 158.0
TLS3_k127_3078681_5 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000008686 113.0
TLS3_k127_3079745_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 534.0
TLS3_k127_3079745_1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 481.0
TLS3_k127_3079745_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 469.0
TLS3_k127_3079745_3 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 364.0
TLS3_k127_3079745_4 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001966 252.0
TLS3_k127_3079745_5 Septum formation - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000001003 147.0
TLS3_k127_3083811_0 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 452.0
TLS3_k127_3083811_1 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 301.0
TLS3_k127_3083811_2 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000001809 198.0
TLS3_k127_3083811_3 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000004055 181.0
TLS3_k127_3094366_0 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 392.0
TLS3_k127_3094366_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006743 314.0
TLS3_k127_3094366_2 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000000000000235 234.0
TLS3_k127_3094366_3 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000001104 156.0
TLS3_k127_3094366_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000009213 123.0
TLS3_k127_3095404_0 Cell envelope-related transcriptional attenuator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000006264 234.0
TLS3_k127_3095404_1 Fungal trichothecene efflux pump (TRI12) - - - 0.0000003057 58.0
TLS3_k127_3095404_2 Transcriptional regulator, MarR family - - - 0.00004399 53.0
TLS3_k127_3177979_0 penicillin-binding protein - GO:0001666,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006950,GO:0008144,GO:0008150,GO:0008658,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0033218,GO:0033293,GO:0033554,GO:0036094,GO:0036293,GO:0036294,GO:0042221,GO:0042597,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0050896,GO:0051716,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0097159,GO:1901363,GO:1901681 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 458.0
TLS3_k127_3177979_1 Family of unknown function (DUF5318) - - - 0.00000000000000000000000000000005677 129.0
TLS3_k127_3194421_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 289.0
TLS3_k127_3194421_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000002433 179.0
TLS3_k127_3194421_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576 2.7.6.1 0.00000000000000000000000000000000000000009202 152.0
TLS3_k127_3194421_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000001814 153.0
TLS3_k127_320282_0 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 526.0
TLS3_k127_320282_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000004988 259.0
TLS3_k127_320282_2 ChrR Cupin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002367 235.0
TLS3_k127_3208125_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 3.08e-200 633.0
TLS3_k127_3208125_1 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 571.0
TLS3_k127_3208125_10 nUDIX hydrolase K01515,K15634 - 3.6.1.13,5.4.2.12 0.0000000000000000000000000000000000000002841 163.0
TLS3_k127_3208125_11 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000003465 128.0
TLS3_k127_3208125_12 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000006 108.0
TLS3_k127_3208125_13 Protein of unknown function (DUF983) - - - 0.0000000000000000000552 100.0
TLS3_k127_3208125_14 - - - - 0.00000000000000824 83.0
TLS3_k127_3208125_15 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000008271 80.0
TLS3_k127_3208125_16 Thioesterase-like superfamily - - - 0.00000000004942 73.0
TLS3_k127_3208125_17 serine-type aminopeptidase activity K14475 - - 0.00007383 51.0
TLS3_k127_3208125_2 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 498.0
TLS3_k127_3208125_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 328.0
TLS3_k127_3208125_4 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 303.0
TLS3_k127_3208125_5 Acetyl-CoA acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 283.0
TLS3_k127_3208125_6 Protein of unknown function (DUF3376) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002834 294.0
TLS3_k127_3208125_7 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000003558 248.0
TLS3_k127_3208125_8 Uncharacterized protein conserved in bacteria (DUF2332) - - - 0.00000000000000000000000000000000000000000000000000000003879 212.0
TLS3_k127_3208125_9 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000002313 183.0
TLS3_k127_3210052_0 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07684 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 285.0
TLS3_k127_3210052_1 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000363 230.0
TLS3_k127_3210052_2 Type ii secretion system K12510 - - 0.00000000000000000000000000000000000000000000000000001849 209.0
TLS3_k127_3210052_3 Histidine kinase K07778 - 2.7.13.3 0.00000000000000000000000000000000000000000000000001774 188.0
TLS3_k127_3210052_4 PFAM type II secretion system K12511 - - 0.0000000000000000000000000000000000000000000000006723 200.0
TLS3_k127_3210052_5 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000007116 147.0
TLS3_k127_3210052_6 Flp/Fap pilin component K02651 - - 0.000006976 50.0
TLS3_k127_3211803_0 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 589.0
TLS3_k127_3211803_1 endonuclease activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008091 302.0
TLS3_k127_3211803_2 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000003573 233.0
TLS3_k127_3211803_3 oxidation-reduction process K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000001569 161.0
TLS3_k127_3230844_0 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 493.0
TLS3_k127_3230844_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000004328 144.0
TLS3_k127_3255942_0 Steryl acetyl hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 369.0
TLS3_k127_3255942_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 308.0
TLS3_k127_3255942_2 Glyoxalase-like domain K08234 - - 0.00000000000000000000000000000000000000000000000000000000006734 213.0
TLS3_k127_3260406_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 546.0
TLS3_k127_3271528_0 Activator of hsp90 atpase 1 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 299.0
TLS3_k127_3271528_1 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000000000004754 175.0
TLS3_k127_3271528_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000001658 139.0
TLS3_k127_3271528_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000005673 114.0
TLS3_k127_3271528_5 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.000686 44.0
TLS3_k127_3281739_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 437.0
TLS3_k127_3281739_1 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001351 269.0
TLS3_k127_3281739_2 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001471 249.0
TLS3_k127_3281739_3 Allophanate hydrolase subunit 2 K01941 - 6.3.4.6 0.0000000000002376 73.0
TLS3_k127_3299145_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 375.0
TLS3_k127_3299145_1 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 310.0
TLS3_k127_3299145_2 PFAM Glycoside hydrolase 15-related - - - 0.00000000000000000000000000000000000000000000000000000001526 203.0
TLS3_k127_3300939_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 9.375e-209 657.0
TLS3_k127_3300939_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000002353 222.0
TLS3_k127_3304657_0 PFAM AMP-dependent synthetase and ligase K18661 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008661 407.0
TLS3_k127_3304657_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002657 248.0
TLS3_k127_3304657_2 Zinc-binding dehydrogenase K19745 - - 0.000000000000000000000000000000000000000000000000000000000000013 219.0
TLS3_k127_3337168_0 ATPase component of ABC transporters with duplicated ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 527.0
TLS3_k127_3337168_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 357.0
TLS3_k127_3337168_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000001031 181.0
TLS3_k127_3337168_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000001758 173.0
TLS3_k127_3379559_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 2.943e-194 612.0
TLS3_k127_3379559_1 Enoyl-(Acyl carrier protein) reductase K00038 - 1.1.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001507 281.0
TLS3_k127_3379559_2 sigma-70 region 2 K03088 - - 0.000000000612 63.0
TLS3_k127_343863_0 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 296.0
TLS3_k127_343863_1 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.000000000000000000002234 109.0
TLS3_k127_343863_2 AMP-dependent synthetase - - - 0.000007298 50.0
TLS3_k127_3441100_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 316.0
TLS3_k127_3441100_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 290.0
TLS3_k127_3441100_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001639 291.0
TLS3_k127_3441100_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002089 288.0
TLS3_k127_3441100_4 Is able to cleave peptidoglycan and affects clumping and separation of bacterial cells - - - 0.000121 52.0
TLS3_k127_3442810_0 Type ii secretion system protein e K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006779 251.0
TLS3_k127_3442810_1 Domain of unknown function (DUF1998) K06877 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003628 244.0
TLS3_k127_3442810_2 Type II secretion system (T2SS), protein F K12511 - - 0.000000000000000000005809 107.0
TLS3_k127_3442810_3 PFAM TadE family protein - - - 0.00000000001205 72.0
TLS3_k127_3442810_5 Type II secretion system (T2SS), protein F K12510 - - 0.000002867 58.0
TLS3_k127_3444651_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 451.0
TLS3_k127_3444651_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 329.0
TLS3_k127_3444651_10 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000001388 188.0
TLS3_k127_3444651_11 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000009422 190.0
TLS3_k127_3444651_12 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000000000000000000000003819 159.0
TLS3_k127_3444651_13 Evidence 4 Homologs of previously reported genes of K09700 - - 0.000000000000000000000000000000000000000003896 158.0
TLS3_k127_3444651_14 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000006671 142.0
TLS3_k127_3444651_15 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0008150,GO:0040007 5.4.2.10 0.000000000000000000000000000009784 122.0
TLS3_k127_3444651_16 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000000844 76.0
TLS3_k127_3444651_2 Encapsulating protein for peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 295.0
TLS3_k127_3444651_3 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 289.0
TLS3_k127_3444651_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000001207 228.0
TLS3_k127_3444651_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000002974 230.0
TLS3_k127_3444651_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000004761 218.0
TLS3_k127_3444651_7 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000000000002996 211.0
TLS3_k127_3444651_8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000029 192.0
TLS3_k127_3444651_9 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000001293 185.0
TLS3_k127_3446678_0 Protein of unknown function (DUF4012) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006016 284.0
TLS3_k127_3446678_1 biosynthesis protein K08252,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000001208 190.0
TLS3_k127_3446678_2 - - - - 0.0000000000000000000009746 104.0
TLS3_k127_3447866_0 Acyclic terpene utilisation family protein AtuA - - - 2.586e-204 652.0
TLS3_k127_3447866_1 carboxylase K01965,K01968 - 6.4.1.3,6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 582.0
TLS3_k127_3447866_2 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 288.0
TLS3_k127_3454616_0 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 601.0
TLS3_k127_3454616_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 407.0
TLS3_k127_3454616_2 TIGRFAM conserved repeat domain - - - 0.0000000924 61.0
TLS3_k127_3480443_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 467.0
TLS3_k127_3480443_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 284.0
TLS3_k127_3480443_2 Zn-ribbon protein, possibly nucleic acid-binding K07164 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000003843 172.0
TLS3_k127_3480443_3 - - - - 0.0000000000000000000000000000001723 134.0
TLS3_k127_3483883_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 364.0
TLS3_k127_3483883_1 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 338.0
TLS3_k127_3483883_2 Chromate K07240 - - 0.00000006123 56.0
TLS3_k127_3490658_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 2.742e-221 709.0
TLS3_k127_3490658_1 Nitronate monooxygenase - - - 2.141e-216 674.0
TLS3_k127_3490658_10 Carboxylesterase family - - - 0.0000000000000000000000002457 106.0
TLS3_k127_3490658_2 COGs COG1253 Hemolysins and related protein containing CBS domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009943 543.0
TLS3_k127_3490658_3 COGs COG1253 Hemolysins and related protein containing CBS domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 514.0
TLS3_k127_3490658_4 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 379.0
TLS3_k127_3490658_5 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000000000000000000000000000006769 243.0
TLS3_k127_3490658_6 glyoxalase bleomycin resistance protein dioxygenase - GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 - 0.00000000000000000000000000000000000000000000000000000000005171 209.0
TLS3_k127_3490658_7 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000000000000007019 173.0
TLS3_k127_3490658_8 transcriptional regulator K03892 - - 0.00000000000000000000000000000000001047 138.0
TLS3_k127_3490658_9 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000005352 132.0
TLS3_k127_3492571_0 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 384.0
TLS3_k127_3492571_1 ABC 3 transport family K09816,K09819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 332.0
TLS3_k127_3492571_2 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003216 265.0
TLS3_k127_3492571_3 Zinc-uptake complex component A periplasmic K02077,K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002141 259.0
TLS3_k127_3494013_0 Pfam Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 364.0
TLS3_k127_3494013_1 Alpha beta hydrolase K01563 - 3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 358.0
TLS3_k127_3494013_2 NIPSNAP family containing protein - - - 0.0000000000889 67.0
TLS3_k127_3499719_0 Alkyl sulfatase dimerisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 423.0
TLS3_k127_3499719_1 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002552 268.0
TLS3_k127_3500837_0 Cytochrome P450 K20497 - 1.14.15.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 469.0
TLS3_k127_3500837_1 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000003104 254.0
TLS3_k127_3500837_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772,K19696 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28,2.4.2.44 0.00000000000000000000000000000000000000000000000007732 188.0
TLS3_k127_3505375_0 Aldehyde dehydrogenase family - - - 3.768e-203 640.0
TLS3_k127_3505375_1 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 419.0
TLS3_k127_3508241_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 603.0
TLS3_k127_3508241_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 321.0
TLS3_k127_3508241_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 310.0
TLS3_k127_3508241_3 alpha beta - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000297 230.0
TLS3_k127_3508241_4 6-pyruvoyl tetrahydropterin synthase K01737 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0070497,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000008749 183.0
TLS3_k127_3516095_0 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 389.0
TLS3_k127_3516095_1 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 302.0
TLS3_k127_3516095_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000002034 196.0
TLS3_k127_3516724_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 290.0
TLS3_k127_3516724_1 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000002974 226.0
TLS3_k127_3516724_2 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000003445 99.0
TLS3_k127_3519140_0 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 300.0
TLS3_k127_3519140_1 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 307.0
TLS3_k127_3519140_2 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005628 284.0
TLS3_k127_3519140_3 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000003981 191.0
TLS3_k127_3519140_4 E1-E2 ATPase K12952 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 - 0.0000000000000000000000000000000008868 134.0
TLS3_k127_3519140_5 Universal stress protein - - - 0.000000000000000000000000000000005548 140.0
TLS3_k127_3519140_6 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000741 121.0
TLS3_k127_3519140_7 sigma factor antagonist activity K04757 - 2.7.11.1 0.0000000003746 68.0
TLS3_k127_3522141_0 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 477.0
TLS3_k127_3522141_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 333.0
TLS3_k127_3522141_10 Psort location Cytoplasmic, score - - - 0.0000005351 61.0
TLS3_k127_3522141_11 - - - - 0.000001943 49.0
TLS3_k127_3522141_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 326.0
TLS3_k127_3522141_3 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002422 259.0
TLS3_k127_3522141_4 Dehydrogenase - GO:0003674,GO:0003824,GO:0004799,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008168,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016740,GO:0016741,GO:0019889,GO:0032259,GO:0033554,GO:0034599,GO:0042083,GO:0042221,GO:0042558,GO:0044237,GO:0046483,GO:0047040,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071704,GO:1901360,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000007622 251.0
TLS3_k127_3522141_5 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000001297 234.0
TLS3_k127_3522141_6 KR domain - - - 0.000000000000000000000000000000000000000000000001582 185.0
TLS3_k127_3522141_7 integral membrane protein - - - 0.000000000000000000000000000000000000000000004746 186.0
TLS3_k127_3522141_8 EthD domain - - - 0.0000000000000000000000000000000003383 137.0
TLS3_k127_3522141_9 SnoaL-like domain - - - 0.00000000000000000000000002937 126.0
TLS3_k127_3524488_0 GIY-YIG type nucleases (URI domain) K02342 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 528.0
TLS3_k127_3524488_1 Calx-beta domain K01179,K01183 - 3.2.1.14,3.2.1.4 0.0000000000000000000000000000000000004534 157.0
TLS3_k127_3524488_2 YacP-like NYN domain - - - 0.00000000000000000000000002539 124.0
TLS3_k127_3524488_3 - - - - 0.00000000000000000000005169 101.0
TLS3_k127_3536115_0 ABC transporter - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 2.051e-289 895.0
TLS3_k127_3536115_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234 2.7.1.25,2.7.7.4 9.061e-204 639.0
TLS3_k127_3536115_2 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 590.0
TLS3_k127_3536115_3 Zc3h12a-like Ribonuclease NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 302.0
TLS3_k127_3536115_4 Catalyzes the synthesis of activated sulfate K00955,K00956 GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006124 279.0
TLS3_k127_3536115_5 hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000007164 211.0
TLS3_k127_3538830_0 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 611.0
TLS3_k127_3538830_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 413.0
TLS3_k127_3541303_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 392.0
TLS3_k127_3541303_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 346.0
TLS3_k127_3541303_2 cytochrome p450 K16046 - 1.14.13.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 315.0
TLS3_k127_3541303_3 PFAM MaoC like domain - - - 0.0000000000000000000000007316 113.0
TLS3_k127_3541303_4 dehydrogenases and related proteins - - - 0.0000000000000000000000164 117.0
TLS3_k127_3541303_5 Calx-beta domain - - - 0.000000000008841 76.0
TLS3_k127_3541303_6 Bacterial regulatory proteins, tetR family - - - 0.00000009658 61.0
TLS3_k127_3546288_0 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000002729 212.0
TLS3_k127_3546288_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000004022 163.0
TLS3_k127_3546288_2 NIPSNAP family containing protein - - - 0.00000000000000000000000000000000008911 145.0
TLS3_k127_3546288_3 Protein of unknown function (DUF2855) - - - 0.0000000000000000000000000001972 117.0
TLS3_k127_3552290_0 NADH:flavin oxidoreductase / NADH oxidase family K00317 - 1.5.8.1,1.5.8.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 504.0
TLS3_k127_3552290_1 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 468.0
TLS3_k127_3552290_2 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000006624 234.0
TLS3_k127_3552290_3 SnoaL-like domain - - - 0.0000000000000000000000000001376 120.0
TLS3_k127_3552290_4 Acyl-CoA dehydrogenase, middle domain - - - 0.0007844 42.0
TLS3_k127_3555319_0 ferredoxin oxidoreductase, beta subunit K00175 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016625,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0047553,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.2.7.11,1.2.7.3 4.997e-203 649.0
TLS3_k127_3555319_1 ferredoxin oxidoreductase K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 494.0
TLS3_k127_3564935_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.092e-201 636.0
TLS3_k127_3564935_1 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 539.0
TLS3_k127_3564935_2 - - - - 0.0000000000000000000007793 97.0
TLS3_k127_3564935_3 cell cycle K05589,K13052 - - 0.000000008711 67.0
TLS3_k127_3572938_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 456.0
TLS3_k127_3572938_1 Formamidopyrimidine-DNA glycosylase H2TH domain K05522 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.000000000000000000000000000000000000002628 151.0
TLS3_k127_3572938_2 Nuclear transport factor 2 (NTF2) domain K01822 - 5.3.3.1 0.000000000000000000000001388 107.0
TLS3_k127_3572938_3 helix_turn_helix, Lux Regulon - - - 0.000000003359 66.0
TLS3_k127_3599920_0 alcohol dehydrogenase K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 392.0
TLS3_k127_3600313_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 390.0
TLS3_k127_3600313_1 Thiamine pyrophosphate enzyme, central domain - - - 0.00000000000000000000000000000000000000000000000000000000004037 222.0
TLS3_k127_3600313_2 - - - - 0.000000000000002613 85.0
TLS3_k127_3610655_0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001059 282.0
TLS3_k127_3610655_1 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000002045 217.0
TLS3_k127_3617411_0 Carboxylesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 357.0
TLS3_k127_3617411_1 Belongs to the long-chain O-acyltransferase family K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007632 338.0
TLS3_k127_3617411_2 Metal-dependent hydrolase K07044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002265 261.0
TLS3_k127_3627069_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 2.21e-215 681.0
TLS3_k127_3627393_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 347.0
TLS3_k127_3627393_1 Belongs to the DegT DnrJ EryC1 family K12452,K13328 - 1.17.1.1,4.2.1.164 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003289 270.0
TLS3_k127_3628962_0 Belongs to the thiolase family - - - 1.863e-196 626.0
TLS3_k127_3628962_1 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 381.0
TLS3_k127_3628962_2 Short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 319.0
TLS3_k127_3628962_3 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003987 287.0
TLS3_k127_3628962_4 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.000000000000000000000000000000000000000000000000000001091 196.0
TLS3_k127_3628962_5 - - - - 0.00000000125 64.0
TLS3_k127_3628962_6 helix_turn_helix, Lux Regulon - - - 0.000000057 64.0
TLS3_k127_3629788_0 Acyl-CoA dehydrogenase N terminal K20035 - - 1.73e-208 666.0
TLS3_k127_3629788_1 cytochrome P-450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 410.0
TLS3_k127_3629788_10 Ring hydroxylating beta subunit - - - 0.000000000000000000000000000000000000000002819 159.0
TLS3_k127_3629788_11 Phosphotransferase enzyme family - - - 0.00000000000000000000000001323 122.0
TLS3_k127_3629788_12 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000000000001014 89.0
TLS3_k127_3629788_13 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000001796 74.0
TLS3_k127_3629788_14 PFAM regulatory protein TetR - - - 0.00000005194 60.0
TLS3_k127_3629788_2 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008902 381.0
TLS3_k127_3629788_3 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 391.0
TLS3_k127_3629788_4 NAD dependent epimerase dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 374.0
TLS3_k127_3629788_5 KR domain K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 352.0
TLS3_k127_3629788_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 295.0
TLS3_k127_3629788_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002616 291.0
TLS3_k127_3629788_8 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000004396 214.0
TLS3_k127_3629788_9 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000809 216.0
TLS3_k127_3633924_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 381.0
TLS3_k127_3633924_1 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006488 279.0
TLS3_k127_3633924_2 - - - - 0.000000009016 66.0
TLS3_k127_3642606_0 Belongs to the GPI family K01810 - 5.3.1.9 3.399e-232 728.0
TLS3_k127_3642606_1 Aldose 1-epimerase - - - 0.00000000000000000000000000000000006157 138.0
TLS3_k127_3646516_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 1.206e-253 790.0
TLS3_k127_3646516_1 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008778 279.0
TLS3_k127_3646516_2 PFAM RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005176 274.0
TLS3_k127_3646516_3 membrane - - - 0.00000000000000000000000000000000000000149 168.0
TLS3_k127_3646570_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 598.0
TLS3_k127_3646570_1 - - - - 0.0000000000000000000000000000000000000000000000000000006269 205.0
TLS3_k127_3646570_2 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000006516 120.0
TLS3_k127_3646570_3 Domain of unknown function (DUF4397) - - - 0.000000000000000000007711 100.0
TLS3_k127_3652047_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 521.0
TLS3_k127_3652047_1 KR domain K00059 GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 383.0
TLS3_k127_3655847_0 Rieske 2Fe-2S - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 599.0
TLS3_k127_3655847_1 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 529.0
TLS3_k127_3655847_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000204 257.0
TLS3_k127_3655847_3 - - - - 0.000000000000000000000000000000000000003981 155.0
TLS3_k127_3660580_0 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 408.0
TLS3_k127_3660580_1 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001747 279.0
TLS3_k127_3660580_2 Domain of unknown function (DUF1731) K07071 - - 0.0000003243 53.0
TLS3_k127_3661232_0 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 379.0
TLS3_k127_3661232_1 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006972 308.0
TLS3_k127_3661232_2 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000005556 228.0
TLS3_k127_3661232_3 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000001301 202.0
TLS3_k127_3661232_4 protein some members contain a von Willebrand factor type A vWA domain - - - 0.0000000000000000000000000000000002347 147.0
TLS3_k127_3668684_0 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 490.0
TLS3_k127_3668684_1 chorismate binding enzyme K02552 - 5.4.4.2 0.0000000000000000000000000000000003296 133.0
TLS3_k127_3669777_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 4.355e-251 785.0
TLS3_k127_3669777_1 Protein of unknown function (DUF503) K09764 - - 0.00000000000006419 75.0
TLS3_k127_3685177_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009554 593.0
TLS3_k127_3685177_1 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 398.0
TLS3_k127_3690140_0 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 494.0
TLS3_k127_3690140_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 329.0
TLS3_k127_3690140_2 - - - - 0.00000000000000000000000000000000000000000000000000004308 195.0
TLS3_k127_3690140_5 - - - - 0.00000000000001199 82.0
TLS3_k127_3690140_7 Psort location Cytoplasmic, score - - - 0.0009052 47.0
TLS3_k127_3695371_0 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 6.499e-217 680.0
TLS3_k127_3695371_1 Carboxyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 334.0
TLS3_k127_3695371_2 Phenazine biosynthesis-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007306 277.0
TLS3_k127_3698622_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1977.0
TLS3_k127_3698622_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000002844 81.0
TLS3_k127_37000_0 SNF2 family N-terminal domain - - - 5.4e-323 1004.0
TLS3_k127_3704487_0 bifunctional deaminase-reductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 319.0
TLS3_k127_3704487_1 HNH endonuclease - - - 0.0000000000000000001349 97.0
TLS3_k127_3704928_0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K00441 - 1.12.98.1 1.746e-205 652.0
TLS3_k127_3704928_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 529.0
TLS3_k127_3704928_2 FAD linked oxidase domain protein K00103 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0016491,GO:0016627,GO:0016632,GO:0019752,GO:0019852,GO:0019853,GO:0030312,GO:0042364,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046364,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:0080049,GO:1901576 1.1.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 359.0
TLS3_k127_3704928_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 323.0
TLS3_k127_3704928_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 302.0
TLS3_k127_3704928_5 Histidine phosphatase superfamily (branch 1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003713 281.0
TLS3_k127_3704928_6 Phosphatidylinositol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000111 256.0
TLS3_k127_3704928_7 Protein of unknown function (DUF3090) - - - 0.000000000000000000000000000000002427 141.0
TLS3_k127_3714472_0 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 364.0
TLS3_k127_3714472_1 - - - - 0.0003711 53.0
TLS3_k127_3723111_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 342.0
TLS3_k127_3750883_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 380.0
TLS3_k127_3750883_1 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008414 252.0
TLS3_k127_3750883_2 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000001831 206.0
TLS3_k127_3750883_3 Ferric uptake regulator family K22297 - - 0.000000000000000000000000000000000000000000000003056 178.0
TLS3_k127_3757215_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 321.0
TLS3_k127_3757215_1 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000002227 237.0
TLS3_k127_3757215_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000003146 187.0
TLS3_k127_3757215_3 HNH endonuclease - - - 0.0000000000000000000000001531 116.0
TLS3_k127_3757215_4 hydrolase of the alpha beta K07018 - - 0.000007758 52.0
TLS3_k127_3760118_0 Lipase (class 2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 301.0
TLS3_k127_3760118_1 Belongs to the agmatine deiminase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005084 279.0
TLS3_k127_3763648_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 451.0
TLS3_k127_3763648_1 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 398.0
TLS3_k127_3763648_2 Bacterial extracellular solute-binding protein - - - 0.000000000000005388 85.0
TLS3_k127_3763648_3 2OG-Fe(II) oxygenase - - - 0.000004127 48.0
TLS3_k127_3768274_0 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000001671 208.0
TLS3_k127_3768274_1 Alcohol dehydrogenase, class IV K00217 - 1.3.1.32 0.0000000000000000000000000000000000000000000000000000002063 212.0
TLS3_k127_3768274_2 PFAM LmbE family protein - - - 0.0000000000000000000001949 100.0
TLS3_k127_3769057_0 Flavin-binding monooxygenase-like K03379,K18091 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0044237,GO:0044249,GO:0046483,GO:0055114,GO:0071704,GO:1901334,GO:1901336,GO:1901360,GO:1901362,GO:1901576 1.14.13.170,1.14.13.171,1.14.13.22 1.335e-198 627.0
TLS3_k127_3769057_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000006689 215.0
TLS3_k127_3770180_1 translation initiation factor activity - - - 0.0000000000000000000000000000000000000000000000000000000002562 209.0
TLS3_k127_3770180_2 HNH endonuclease - - - 0.000000000000000000000000000000000009418 140.0
TLS3_k127_3770180_3 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000005042 94.0
TLS3_k127_3770928_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 313.0
TLS3_k127_3770928_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002848 259.0
TLS3_k127_3782463_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 495.0
TLS3_k127_3782463_1 Glycosyl transferase family 4 K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 410.0
TLS3_k127_3782463_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004653 285.0
TLS3_k127_3782463_3 - - - - 0.0000000000000000000000000000000000002648 146.0
TLS3_k127_3782463_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation - - - 0.000000000000000000000000000003459 125.0
TLS3_k127_3782463_5 ATP synthesis coupled proton transport K02109 - - 0.000000000000433 75.0
TLS3_k127_3796367_0 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 573.0
TLS3_k127_3796367_1 dihydrodipicolinate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 420.0
TLS3_k127_3796367_2 metal-dependent hydrolase of the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 336.0
TLS3_k127_3796367_3 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000000000000000007394 106.0
TLS3_k127_3835482_0 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 506.0
TLS3_k127_3835482_1 impB/mucB/samB family K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 505.0
TLS3_k127_3835482_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 362.0
TLS3_k127_3835482_3 Protein of unknown function (DUF1211) - GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022840,GO:0022841,GO:0022842,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000009023 240.0
TLS3_k127_3835482_4 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division - GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000004542 151.0
TLS3_k127_3835482_5 - - - - 0.00000000000000000000001664 103.0
TLS3_k127_3835482_6 VirC1 protein K03496 - - 0.00000002262 55.0
TLS3_k127_3835529_0 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 591.0
TLS3_k127_3842198_0 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 313.0
TLS3_k127_3842198_1 Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000000000000000000009631 202.0
TLS3_k127_3842198_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000004945 61.0
TLS3_k127_3845612_0 Belongs to the anti-sigma-factor antagonist family K04749 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000006809 105.0
TLS3_k127_3845612_2 Domain of unknown function (DUF1998) K06877 - - 0.00000000000000006763 91.0
TLS3_k127_3845612_3 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000005126 66.0
TLS3_k127_3859958_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000001142 188.0
TLS3_k127_3859958_1 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.0000000001452 61.0
TLS3_k127_3867123_0 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 456.0
TLS3_k127_3867123_1 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 312.0
TLS3_k127_3867123_2 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000000000000002698 162.0
TLS3_k127_3867123_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000002607 153.0
TLS3_k127_3884022_0 ABC transporter - - - 4.933e-307 945.0
TLS3_k127_3884022_1 zinc transporter K07238 - - 0.0000000000607 66.0
TLS3_k127_3894974_0 Domain of unknown function (DUF4388) - - - 0.00000000000009294 80.0
TLS3_k127_3894974_1 Nitrate and nitrite sensing - - - 0.00000007401 64.0
TLS3_k127_3894974_2 Host cell surface-exposed lipoprotein - - - 0.0003987 44.0
TLS3_k127_38989_0 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 338.0
TLS3_k127_38989_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002908 259.0
TLS3_k127_3906385_0 cytochrome P450 - - - 0.00000000000000000000000000000000000000000004801 177.0
TLS3_k127_3906565_0 Acyl-CoA dehydrogenase, middle domain K09456 - - 5.362e-220 695.0
TLS3_k127_3906565_1 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 304.0
TLS3_k127_3906565_2 cAMP biosynthetic process K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000001306 233.0
TLS3_k127_3906565_3 - - - - 0.0000000000000000000000000000000000000000000000000000007175 205.0
TLS3_k127_3906565_4 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000004803 89.0
TLS3_k127_3929203_0 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 374.0
TLS3_k127_3929203_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000004728 233.0
TLS3_k127_3929203_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000009744 213.0
TLS3_k127_3929203_3 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000000000002513 172.0
TLS3_k127_3929203_4 - - - - 0.000000000000000000000001047 107.0
TLS3_k127_3932065_0 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity K08080,K14952 - 1.14.18.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 482.0
TLS3_k127_3932065_1 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000909 130.0
TLS3_k127_3932065_2 PFAM Sporulation and spore germination - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000007001 59.0
TLS3_k127_3949012_0 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 508.0
TLS3_k127_3949012_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 393.0
TLS3_k127_3949012_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001381 273.0
TLS3_k127_3949012_3 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001327 262.0
TLS3_k127_3949012_4 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000007792 224.0
TLS3_k127_3949012_5 Aldolase K01628,K03077,K22130 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019324,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 4.1.1.104,4.1.2.17,5.1.3.4 0.0000000000000000000000000000000000000000000000000000000002122 215.0
TLS3_k127_3949012_6 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000004959 203.0
TLS3_k127_3949012_7 Electron transfer flavoprotein FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000009563 190.0
TLS3_k127_3949012_8 - - - - 0.00000000000000005296 87.0
TLS3_k127_396337_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 308.0
TLS3_k127_396337_1 Domain of unknown function (DUF4397) - - - 0.000000008824 66.0
TLS3_k127_396337_2 Domain of unknown function (DUF4397) - - - 0.00000587 57.0
TLS3_k127_3991426_0 NAD(P)-binding Rossmann-like domain K03379 - 1.14.13.22 2.363e-224 701.0
TLS3_k127_3991426_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 581.0
TLS3_k127_3991426_2 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 440.0
TLS3_k127_3991426_3 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000000000001241 161.0
TLS3_k127_4007301_0 helicase superfamily c-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 520.0
TLS3_k127_4014021_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 340.0
TLS3_k127_4014021_1 PLD-like domain - - - 0.00002678 52.0
TLS3_k127_4017593_0 pilus organization - - - 0.00000000000000005936 94.0
TLS3_k127_4021177_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 321.0
TLS3_k127_4021177_1 Domain of unknown function (DUF2520) - - - 0.0000000000000000000000000000000000000000000001785 174.0
TLS3_k127_4021177_2 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000003926 156.0
TLS3_k127_4021177_3 Fumarate reductase flavoprotein C-term K00278,K00767 GO:0008150,GO:0040007 1.4.3.16,2.4.2.19 0.000000001211 60.0
TLS3_k127_4022672_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008702 428.0
TLS3_k127_4022672_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000001847 157.0
TLS3_k127_4022672_2 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000004989 99.0
TLS3_k127_402712_0 Zn-dependent metallo-hydrolase RNA specificity domain K12574 - - 2.982e-227 718.0
TLS3_k127_402712_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 463.0
TLS3_k127_402712_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000001659 268.0
TLS3_k127_402712_3 Belongs to the FtsK SpoIIIE SftA family K03466 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000004718 91.0
TLS3_k127_4045724_0 phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 318.0
TLS3_k127_4045724_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 325.0
TLS3_k127_4045724_2 phosphate transport system permease K02038 - - 0.0000000000000000001145 95.0
TLS3_k127_4048899_0 PFAM PKD domain containing protein - - - 2.995e-294 954.0
TLS3_k127_4048899_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000002177 80.0
TLS3_k127_4053399_0 B12 binding domain K00548 - 2.1.1.13 3.929e-202 636.0
TLS3_k127_4053399_1 DNA polymerase LigD polymerase domain K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000001252 138.0
TLS3_k127_4053399_2 PFAM blue (type 1) copper domain protein - - - 0.0000000000000006517 89.0
TLS3_k127_4058430_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 368.0
TLS3_k127_4058430_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000003971 263.0
TLS3_k127_4058430_2 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000004227 169.0
TLS3_k127_4061124_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.089e-289 902.0
TLS3_k127_4061124_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 554.0
TLS3_k127_4061124_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 416.0
TLS3_k127_4061124_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 336.0
TLS3_k127_4061124_4 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 321.0
TLS3_k127_4061124_5 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000278 291.0
TLS3_k127_4061124_6 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004358 245.0
TLS3_k127_4061124_7 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000925 181.0
TLS3_k127_4061124_8 Acetyltransferase (Isoleucine patch superfamily) K00633,K00661 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008374,GO:0008925,GO:0009987,GO:0016043,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0022607,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840 2.3.1.18,2.3.1.79 0.00000000003825 64.0
TLS3_k127_4091399_0 hydrolase, family 25 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 449.0
TLS3_k127_4091399_2 isomerase activity - - - 0.00000000000000000004923 105.0
TLS3_k127_4110560_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 327.0
TLS3_k127_4110560_1 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 305.0
TLS3_k127_4110560_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000004345 211.0
TLS3_k127_4110560_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000003913 168.0
TLS3_k127_4110560_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000006883 165.0
TLS3_k127_413779_0 Chromosome Partitioning - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 318.0
TLS3_k127_413779_1 pfam chad - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000101 284.0
TLS3_k127_413779_2 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.00000000000000000000000000000000000000001073 155.0
TLS3_k127_413779_3 ACT domain - - - 0.0000000000005257 75.0
TLS3_k127_4140578_0 phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 463.0
TLS3_k127_4140578_1 Polyprenyl synthetase K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 338.0
TLS3_k127_4140578_2 lycopene cyclase - - - 0.0000000000000000000000000000000000147 139.0
TLS3_k127_4140578_3 overlaps another CDS with the same product name - - - 0.0000000000000000000000000000000009929 139.0
TLS3_k127_4140578_4 Sulfatase - - - 0.0000000000000000000000000000175 127.0
TLS3_k127_4140578_5 Fatty acid hydroxylase superfamily K15746 - 1.14.15.24 0.0000000000000000000000000001215 129.0
TLS3_k127_4196261_0 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 310.0
TLS3_k127_4196261_1 Acetyltransferase (isoleucine patch K00661 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 2.3.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000008084 252.0
TLS3_k127_4196261_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001086 245.0
TLS3_k127_4196261_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000001051 147.0
TLS3_k127_4196261_4 heat shock protein binding K03686,K05516 - - 0.0000000001388 70.0
TLS3_k127_4207246_0 Acetyltransferase (GNAT) domain K03825 - - 0.00000000000000000000000000000000000000001287 159.0
TLS3_k127_4207246_1 Sigma-70, region 4 - - - 0.00000000000000000000000002675 119.0
TLS3_k127_4207246_2 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.00000000000001473 84.0
TLS3_k127_4207246_3 DNA replication proofreading K02336,K06877,K07501 - 2.7.7.7 0.0001817 53.0
TLS3_k127_4218547_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000001482 109.0
TLS3_k127_4218547_1 ABC-2 family transporter protein - - - 0.000000000000000000001334 109.0
TLS3_k127_4230662_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 455.0
TLS3_k127_4230662_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007598 371.0
TLS3_k127_4230662_2 Prephenate dehydrogenase K00210,K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 352.0
TLS3_k127_4230662_3 RNA pseudouridylate synthase K06178,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 304.0
TLS3_k127_4230662_4 Cytidylate kinase K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000547 208.0
TLS3_k127_4230662_5 Phosphohydrolase - - - 0.000000000000000000000000000000000000000000000000000000001883 206.0
TLS3_k127_4230662_6 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000002462 193.0
TLS3_k127_4230662_7 Chorismate mutase type I K06208 - 5.4.99.5 0.0000000000000000000000000000000000000000000003564 169.0
TLS3_k127_425823_0 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 501.0
TLS3_k127_425823_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 488.0
TLS3_k127_425823_2 Uncharacterized conserved protein (DUF2267) - - - 0.0000000000000002777 80.0
TLS3_k127_4263630_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 563.0
TLS3_k127_4263630_1 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 396.0
TLS3_k127_4263630_2 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000001344 89.0
TLS3_k127_4265191_0 PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain K01941 - 6.3.4.6 0.0 1352.0
TLS3_k127_4265191_1 ABC transporter, substrate-binding protein, aliphatic sulfonates family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 372.0
TLS3_k127_4265191_2 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 317.0
TLS3_k127_4265191_3 Domain of unknown function (DUF1989) K09967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 294.0
TLS3_k127_4265191_4 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000351 207.0
TLS3_k127_429553_0 Putative peptidoglycan binding domain K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000001373 182.0
TLS3_k127_429553_1 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0015037,GO:0015038,GO:0016020,GO:0016209,GO:0016491,GO:0016651,GO:0016657,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0022900,GO:0030312,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0080007,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000000000000009498 144.0
TLS3_k127_4303509_0 ABC transporter K01995 - - 0.0 1026.0
TLS3_k127_4303509_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000003503 67.0
TLS3_k127_4310043_0 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000001034 231.0
TLS3_k127_4310043_1 Capsular exopolysaccharide family K08253 - 2.7.10.2 0.000000000000000000000000000000000000000000000000000000006821 221.0
TLS3_k127_4310043_2 Polysaccharide biosynthesis protein - - - 0.000000000000001188 87.0
TLS3_k127_4312593_0 PFAM AMP-dependent synthetase K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 477.0
TLS3_k127_4312593_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 390.0
TLS3_k127_4312593_2 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 348.0
TLS3_k127_4312593_3 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 325.0
TLS3_k127_4312593_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001726 279.0
TLS3_k127_4313053_0 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 324.0
TLS3_k127_4313053_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 334.0
TLS3_k127_4313053_2 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000003314 171.0
TLS3_k127_4313053_3 heme binding - - - 0.0000000000000000000000002679 119.0
TLS3_k127_4315877_0 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 421.0
TLS3_k127_4315877_1 HD domain - - - 0.0000000000000000000000000000000000000000000000000006138 191.0
TLS3_k127_4315877_2 N-Acetylmuramoyl-L-alanine amidase K01448 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008745,GO:0016787,GO:0016810,GO:0016811,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0061783 3.5.1.28 0.00000000000000000000000000002357 134.0
TLS3_k127_4315877_3 GCN5-related N-acetyl-transferase K02346,K06975 - 2.7.7.7 0.000000000000000000000001212 106.0
TLS3_k127_4315877_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000004757 95.0
TLS3_k127_4318939_0 RecF/RecN/SMC N terminal domain K03529 - - 0.0 1056.0
TLS3_k127_4318939_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 377.0
TLS3_k127_4318939_10 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000004554 92.0
TLS3_k127_4318939_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000001353 248.0
TLS3_k127_4318939_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000001595 233.0
TLS3_k127_4318939_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000003743 222.0
TLS3_k127_4318939_5 ATP synthesis coupled proton transport - - - 0.000000000000000000000000000000000000000000001733 179.0
TLS3_k127_4318939_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000000000009638 154.0
TLS3_k127_4318939_7 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000005106 149.0
TLS3_k127_4318939_8 Uncharacterized ACR, COG1399 K07040 GO:0008150,GO:0040007 - 0.00000000000000000000000000001129 126.0
TLS3_k127_4319428_0 DNA polymerase alpha chain like domain K02337 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.7 0.0 1617.0
TLS3_k127_4319428_2 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000003162 225.0
TLS3_k127_4319639_0 Thiolase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 400.0
TLS3_k127_4319639_1 TIM-barrel fold metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000001281 236.0
TLS3_k127_4319639_2 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000045 175.0
TLS3_k127_4319639_3 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.00000000000000000000000000001152 130.0
TLS3_k127_4319639_4 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000001077 117.0
TLS3_k127_4319639_5 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0000000000000000000001641 101.0
TLS3_k127_4328514_0 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 351.0
TLS3_k127_4328514_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 286.0
TLS3_k127_4328514_2 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000002336 208.0
TLS3_k127_4328514_3 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000007216 165.0
TLS3_k127_4328514_4 transcriptional regulator K13643 - - 0.0000000000000000000000003912 108.0
TLS3_k127_4334921_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.3.14 4.389e-238 751.0
TLS3_k127_4334921_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000002764 177.0
TLS3_k127_4334921_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000002736 154.0
TLS3_k127_4334921_3 ATP synthesis coupled proton transport K02109,K02113 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000002713 112.0
TLS3_k127_4336418_0 FAD dependent oxidoreductase K15736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001155 275.0
TLS3_k127_4336418_1 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004831 278.0
TLS3_k127_4336418_2 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000002379 221.0
TLS3_k127_4352776_0 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008249 428.0
TLS3_k127_4352776_1 N-acetylglucosaminylinositol deacetylase activity K01463 - - 0.00000000000000000000000000000000000000000000000000000000000002432 224.0
TLS3_k127_4352776_2 Cytochrome b/b6/petB K03891 - - 0.000000000000000000000000000000000001376 143.0
TLS3_k127_4352776_3 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000000000000000001971 125.0
TLS3_k127_4354567_0 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 312.0
TLS3_k127_4354567_1 Acetyltransferase (GNAT) domain K02348 - - 0.00000000000000000000000000000000001161 146.0
TLS3_k127_4354567_2 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000001897 53.0
TLS3_k127_4357207_0 GDP-mannose mannosyl hydrolase activity K03574,K06889 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 299.0
TLS3_k127_4357207_1 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000004377 262.0
TLS3_k127_4357207_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096 2.7.7.59 0.0000000000000000006948 92.0
TLS3_k127_436176_0 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 291.0
TLS3_k127_436176_1 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001888 264.0
TLS3_k127_436176_2 MDMPI C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000109 195.0
TLS3_k127_4365928_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000293 162.0
TLS3_k127_4365928_1 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000005655 100.0
TLS3_k127_4371220_0 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000002295 164.0
TLS3_k127_4371220_1 Sulfotransferase family - - - 0.000000000000000003526 100.0
TLS3_k127_4371220_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000006132 72.0
TLS3_k127_4372365_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 294.0
TLS3_k127_4372365_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000005284 239.0
TLS3_k127_4372365_2 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000003916 206.0
TLS3_k127_4372365_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000000000000000000000001107 172.0
TLS3_k127_4372365_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000001488 126.0
TLS3_k127_4372365_5 - - - - 0.00000000000000000000000000004672 131.0
TLS3_k127_4377253_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 581.0
TLS3_k127_4377253_1 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000001262 135.0
TLS3_k127_4382067_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 433.0
TLS3_k127_4382067_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000007115 176.0
TLS3_k127_4382084_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000024 250.0
TLS3_k127_4382084_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0030312,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.2.1.6 0.000000000000000000000000000000000000009999 147.0
TLS3_k127_4382084_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000009279 150.0
TLS3_k127_4382084_3 acetyl-CoA hydrolase K18122 - - 0.000000000000004721 77.0
TLS3_k127_4382349_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 509.0
TLS3_k127_4382349_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 355.0
TLS3_k127_4382349_2 - - - - 0.0000000000000000000000000000000000000000000005773 187.0
TLS3_k127_4382349_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000006344 155.0
TLS3_k127_4384936_0 Aminotransferase class-III - - - 3.388e-202 638.0
TLS3_k127_4384936_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 547.0
TLS3_k127_4384936_2 helix_turn_helix ASNC type K03718 - - 0.0000000000000000000000000000000000000000000000000000001462 203.0
TLS3_k127_4384936_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.00000000000003265 76.0
TLS3_k127_4384936_4 inner membrane component K11070 - - 0.00002812 46.0
TLS3_k127_4391820_0 MOSC domain - - - 0.000000000000000000000000000000000000000000000007068 186.0
TLS3_k127_4391820_1 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.0000000000000000000000000000000000000000000000102 188.0
TLS3_k127_4391820_2 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.0000000000000000000000000000000000004001 141.0
TLS3_k127_4391820_3 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000001691 136.0
TLS3_k127_4391820_4 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000002636 128.0
TLS3_k127_4392660_0 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 474.0
TLS3_k127_4392660_1 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 353.0
TLS3_k127_4392660_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 340.0
TLS3_k127_4392660_3 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006572 299.0
TLS3_k127_4392660_4 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001326 271.0
TLS3_k127_4392660_5 Peptidase s1 and s6 chymotrypsin hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000002197 227.0
TLS3_k127_442528_0 FAD binding domain K05898 - 1.3.99.4 5.544e-203 646.0
TLS3_k127_442528_1 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 525.0
TLS3_k127_442528_2 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 514.0
TLS3_k127_442528_3 peptidase M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002062 271.0
TLS3_k127_442528_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001627 254.0
TLS3_k127_442528_6 PFAM regulatory protein TetR - - - 0.00001221 48.0
TLS3_k127_4429760_0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain - - - 3.078e-266 826.0
TLS3_k127_4429760_1 PFAM regulatory protein AsnC Lrp family - - - 0.0000000000000000000000000003354 115.0
TLS3_k127_4432136_0 Sulfate transporter K03321 - - 3.745e-204 652.0
TLS3_k127_4432136_1 COG3119 Arylsulfatase A and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 489.0
TLS3_k127_4432136_2 Ecdysteroid kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 319.0
TLS3_k127_4432136_3 - - - - 0.0000000000000000001456 104.0
TLS3_k127_4432136_4 Bacterial regulatory proteins, tetR family K22295 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000226 95.0
TLS3_k127_4432136_5 transcriptional regulator - - - 0.0005698 52.0
TLS3_k127_4458046_0 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 436.0
TLS3_k127_4458046_1 Branched-chain amino acid ATP-binding cassette transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003209 248.0
TLS3_k127_4458046_2 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000000000003227 181.0
TLS3_k127_4477008_0 AMP-binding enzyme C-terminal domain - - - 1.01e-212 679.0
TLS3_k127_4477008_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 373.0
TLS3_k127_4477008_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 357.0
TLS3_k127_4477008_3 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009271 289.0
TLS3_k127_4477008_4 amidohydrolase - - - 0.00000000000000000000000000000000000000188 151.0
TLS3_k127_4501976_0 N-4 methylation of cytosine K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009429 492.0
TLS3_k127_4511855_0 Belongs to the complex I 49 kDa subunit family K00333 - 1.6.5.3 7.2e-212 667.0
TLS3_k127_4511855_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009295 394.0
TLS3_k127_4511855_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000003464 221.0
TLS3_k127_4511855_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000007855 97.0
TLS3_k127_4524746_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 608.0
TLS3_k127_4524746_1 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 507.0
TLS3_k127_4524746_2 CoA-transferase family III K01796 - 5.1.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 458.0
TLS3_k127_4524746_3 Cytochrome P450 K15981 - 1.14.13.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 445.0
TLS3_k127_4524746_4 Belongs to the long-chain O-acyltransferase family - GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 449.0
TLS3_k127_4524746_5 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 429.0
TLS3_k127_4524746_6 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 401.0
TLS3_k127_4524746_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000626 262.0
TLS3_k127_4524746_8 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005304 267.0
TLS3_k127_4529269_0 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000003412 157.0
TLS3_k127_4529269_1 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000005017 155.0
TLS3_k127_4529269_2 - - - - 0.000000000000000000000000000000000009716 136.0
TLS3_k127_4529269_3 Peptidase family M23 K21472 - - 0.000000000000002594 79.0
TLS3_k127_4544533_1 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000006431 203.0
TLS3_k127_4544533_2 ubiquinone biosynthetic process - - - 0.000000000000000000000000000000000000000000000000001252 191.0
TLS3_k127_4544533_3 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000000000005129 132.0
TLS3_k127_4550801_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 451.0
TLS3_k127_4550801_1 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 405.0
TLS3_k127_4550801_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000005367 237.0
TLS3_k127_4550801_3 - - - - 0.000000000000000000000000000000000000000000000003308 182.0
TLS3_k127_4550801_4 cyclic nucleotide binding K10914 - - 0.000000000000000000000000000000000000001721 151.0
TLS3_k127_4567431_0 Heavy metal translocating P-type atpase K01533,K17686 - 3.6.3.4,3.6.3.54 4.335e-227 717.0
TLS3_k127_4567431_1 Peptidase family M48 - - - 0.0000000000000000000000000000785 120.0
TLS3_k127_4570350_0 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 464.0
TLS3_k127_4572143_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 2.7e-206 649.0
TLS3_k127_4572143_1 oligosaccharyl transferase activity - - - 0.0000000000000000000000001984 121.0
TLS3_k127_4604526_0 4Fe-4S dicluster domain - - - 5.209e-194 608.0
TLS3_k127_4604526_1 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.0000000003201 68.0
TLS3_k127_4626634_0 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 357.0
TLS3_k127_4626634_1 Transglycosylase associated protein - - - 0.0000000000000000000000000004871 116.0
TLS3_k127_4627521_0 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 383.0
TLS3_k127_4627521_1 Protein of unknown function (DUF3151) - - - 0.0000000000000000000000000000000000000000000000962 175.0
TLS3_k127_4627521_2 sulfurtransferase - - - 0.0000000000000000000000000005079 119.0
TLS3_k127_4627521_3 Glyoxalase-like domain - - - 0.00000000000000000000000582 111.0
TLS3_k127_4627521_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000005409 97.0
TLS3_k127_4627521_5 Sulfite exporter TauE/SafE K07090 - - 0.0000001587 55.0
TLS3_k127_4642642_0 COG0433 Predicted ATPase K06915 - - 3.546e-225 711.0
TLS3_k127_4642642_1 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 374.0
TLS3_k127_4642642_2 Putative exonuclease SbcCD, C subunit K03546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 385.0
TLS3_k127_4664858_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 505.0
TLS3_k127_4664858_1 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 374.0
TLS3_k127_4666705_0 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 599.0
TLS3_k127_4666705_1 Belongs to the MIP aquaporin (TC 1.A.8) family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000176 269.0
TLS3_k127_4666705_2 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000003719 203.0
TLS3_k127_4666705_3 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000001405 132.0
TLS3_k127_4666705_4 nucleic-acid-binding protein containing a zn-ribbon K07068 - - 0.0000000000000000000000000003708 119.0
TLS3_k127_467522_0 Enoyl-CoA hydratase/isomerase K01692,K13766 - 4.2.1.17,4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 338.0
TLS3_k127_467522_1 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 316.0
TLS3_k127_467522_2 Lon protease (S16) C-terminal proteolytic domain K07177 - - 0.00000000000000000000000000000000000000000000000007312 192.0
TLS3_k127_467522_3 PBS lyase HEAT-like repeat - - - 0.000000000000000000000000000000000000000000000528 176.0
TLS3_k127_467522_4 regulation of cell shape K04074 - - 0.00000000000000003387 94.0
TLS3_k127_467522_5 Branched-chain amino acid transport system / permease component K01998 - - 0.0000004489 54.0
TLS3_k127_4687501_0 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 334.0
TLS3_k127_4687501_1 diacylglycerol O-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004354 265.0
TLS3_k127_4687501_2 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.0000000000000000000000000000000000000000171 174.0
TLS3_k127_4687501_3 MaoC like domain - - - 0.00000000000000000000000000000000000001782 149.0
TLS3_k127_4687501_4 RIO1 family - - - 0.0000000000000000000000000000001001 143.0
TLS3_k127_4687501_5 EamA-like transporter family - - - 0.0000000000000002391 92.0
TLS3_k127_4688575_0 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000003473 176.0
TLS3_k127_4688575_1 Protein of unknown function (DUF3445) K22342 - 1.14.13.238 0.000000000000000000000000000000000000000000000006814 183.0
TLS3_k127_4688575_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000005066 163.0
TLS3_k127_4702856_0 Major Facilitator Superfamily - - - 2.061e-200 634.0
TLS3_k127_4702856_1 Pyridoxal-dependent decarboxylase conserved domain K01580 - 4.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000436 241.0
TLS3_k127_4719206_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 386.0
TLS3_k127_4719206_1 PFAM bifunctional deaminase-reductase domain protein - - - 0.000000000000000000000000000000000000000000000000001736 183.0
TLS3_k127_4719206_2 Protein of unknown function (DUF1622) - - - 0.0000000000000000000006047 102.0
TLS3_k127_4719206_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000005753 52.0
TLS3_k127_4721989_0 Belongs to the aldehyde dehydrogenase family - - - 6.947e-200 643.0
TLS3_k127_4721989_1 synthetase K00666,K18688 GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009605,GO:0009607,GO:0009987,GO:0015645,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0030312,GO:0032787,GO:0042546,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051087,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:0075136,GO:1901576 6.2.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 617.0
TLS3_k127_4721989_2 Enoyl-CoA hydratase K01692,K18383 - 4.1.2.41,4.2.1.101,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 329.0
TLS3_k127_4721989_3 Belongs to the long-chain O-acyltransferase family K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000001127 261.0
TLS3_k127_4726045_0 tRNA synthetases class I (C) catalytic domain K01883,K15526 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16,6.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 309.0
TLS3_k127_4726045_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 302.0
TLS3_k127_4726045_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000009403 257.0
TLS3_k127_4743862_0 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 390.0
TLS3_k127_4743862_1 ACT domain - - - 0.00000000000003661 76.0
TLS3_k127_4746116_0 helix_turn_helix, cAMP Regulatory protein K01420,K10914,K21561,K21564 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002453 271.0
TLS3_k127_4746116_1 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001864 245.0
TLS3_k127_4746116_2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000009719 199.0
TLS3_k127_4746116_3 Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000001881 82.0
TLS3_k127_4776178_0 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000004783 241.0
TLS3_k127_4776178_1 - - - - 0.000000000000000000004121 98.0
TLS3_k127_478117_0 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 386.0
TLS3_k127_478117_1 Glycosyl transferase - - - 0.00000000000000000000000000002708 120.0
TLS3_k127_4784060_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.078e-195 625.0
TLS3_k127_4784060_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 517.0
TLS3_k127_4784060_2 Isocitrate/isopropylmalate dehydrogenase K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 456.0
TLS3_k127_4784060_4 - - - - 0.000007264 57.0
TLS3_k127_4792200_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090 - 0.0 1286.0
TLS3_k127_4809691_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 365.0
TLS3_k127_4809691_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000004542 234.0
TLS3_k127_4809691_2 Transcriptional regulator - - - 0.00000000002275 64.0
TLS3_k127_4813334_0 Proton-conducting membrane transporter K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 509.0
TLS3_k127_4813334_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000000000001165 235.0
TLS3_k127_4813334_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904 - 0.00000000000000000000000000000000000000000000008498 172.0
TLS3_k127_4813334_3 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.000000000000000000000000000000000002917 149.0
TLS3_k127_4813334_4 Multisubunit Na H antiporter MnhC subunit K05567 - - 0.0000000000000000000000000002796 120.0
TLS3_k127_4813334_5 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000002371 86.0
TLS3_k127_4813334_6 Na+/H+ ion antiporter subunit K05569 - - 0.0000000000000542 83.0
TLS3_k127_4813334_7 monovalent cation:proton antiporter activity K05571 - - 0.00000000001892 72.0
TLS3_k127_4813334_8 - - - - 0.00000008827 63.0
TLS3_k127_4813334_9 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.0004606 51.0
TLS3_k127_4820731_0 metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 296.0
TLS3_k127_4820731_1 ABC-type transport system involved in Fe-S cluster assembly, ATPase component K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001548 265.0
TLS3_k127_4820731_2 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000000000000003065 221.0
TLS3_k127_4820731_3 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000001479 209.0
TLS3_k127_4820731_4 - - - - 0.0000000000000000000000000000000000000003408 152.0
TLS3_k127_4820731_5 Protein of unknown function (DUF3237) - - - 0.0000000000000000000000000000006377 127.0
TLS3_k127_4820731_6 PFAM Rieske 2Fe-2S K05710 - - 0.000000000000000000000000008471 122.0
TLS3_k127_4820731_7 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000291 113.0
TLS3_k127_4820731_8 - - - - 0.00000002886 65.0
TLS3_k127_4821048_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007519 527.0
TLS3_k127_4821048_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K13252 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 326.0
TLS3_k127_4821048_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000001605 213.0
TLS3_k127_4821048_3 Arginine repressor, DNA binding domain K03402 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000001452 189.0
TLS3_k127_4821048_4 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000004068 168.0
TLS3_k127_4828959_0 Glycogen debranching enzyme - - - 2.445e-206 664.0
TLS3_k127_4828959_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 347.0
TLS3_k127_4828959_2 - - - - 0.0000000000000000000000000000002673 131.0
TLS3_k127_4828959_3 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000000000000000008142 98.0
TLS3_k127_4828959_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.000000001166 67.0
TLS3_k127_4856464_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 402.0
TLS3_k127_4856464_1 methionine sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000002532 168.0
TLS3_k127_4856464_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000002018 108.0
TLS3_k127_4856464_3 - - - - 0.0006783 51.0
TLS3_k127_4865002_0 Domain of unknown function (DUF4842) - - - 0.0000000000000002652 93.0
TLS3_k127_4876417_0 Pterin binding enzyme K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000001264 264.0
TLS3_k127_4876417_1 ComEC Rec2-related protein K02238 - - 0.00000000000000000000000000000000000000000000000007234 195.0
TLS3_k127_488771_0 PhoH-like protein K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 424.0
TLS3_k127_488771_1 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 380.0
TLS3_k127_488771_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 374.0
TLS3_k127_488771_3 HELICc2 K03722 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.4.12 0.0000000000000000000000000000000000000000000000001386 179.0
TLS3_k127_488771_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000005066 142.0
TLS3_k127_488771_5 Helix-turn-helix domain - - - 0.000000000000000115 82.0
TLS3_k127_4897294_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.018e-253 791.0
TLS3_k127_4897294_1 L-lactate permease K03303 - - 6.461e-217 688.0
TLS3_k127_4897294_2 L-lactate permease K03303 - - 3.016e-199 634.0
TLS3_k127_4897294_3 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000000003899 152.0
TLS3_k127_4897294_5 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0002559 44.0
TLS3_k127_4908192_0 Sodium:sulfate symporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 451.0
TLS3_k127_4908192_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 415.0
TLS3_k127_4908192_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000002064 209.0
TLS3_k127_4913372_0 Serine aminopeptidase, S33 K01563 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 438.0
TLS3_k127_4913372_1 amine dehydrogenase activity K07004,K21449 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000221 174.0
TLS3_k127_4913372_3 Transcriptional regulator - - - 0.0000000000000000000000000001616 125.0
TLS3_k127_4913372_4 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 0.000000000000000007963 83.0
TLS3_k127_4913372_5 response to pH - - - 0.000000000000008592 82.0
TLS3_k127_4913372_6 protein homooligomerization - - - 0.00000001638 66.0
TLS3_k127_4921115_0 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 332.0
TLS3_k127_4921115_1 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000002189 209.0
TLS3_k127_4921115_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000007359 149.0
TLS3_k127_4921115_3 - - - - 0.0000000000000000000000000002381 119.0
TLS3_k127_4921115_4 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000001689 53.0
TLS3_k127_4934935_0 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 353.0
TLS3_k127_4934935_1 Glycosyl transferase family 2 K13693 - 2.4.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 305.0
TLS3_k127_4934935_2 ThiS family K03636 - - 0.00000000000000000000000000007532 120.0
TLS3_k127_4954081_0 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 408.0
TLS3_k127_4979519_0 Drug exporters of the RND superfamily K06994 - - 2.326e-207 668.0
TLS3_k127_4979519_1 Steryl acetyl hydrolase - - - 0.0000000000000000000002003 99.0
TLS3_k127_4981284_0 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 612.0
TLS3_k127_4981284_1 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000106 283.0
TLS3_k127_4981284_2 CAAX protease self-immunity K07052 - - 0.00000000000000000000001133 112.0
TLS3_k127_5003842_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 568.0
TLS3_k127_5003842_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 451.0
TLS3_k127_5003842_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 313.0
TLS3_k127_5003842_3 acr, cog1565 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001821 302.0
TLS3_k127_5003842_4 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000588 246.0
TLS3_k127_5012185_0 Type ii secretion system protein e K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 556.0
TLS3_k127_5012185_1 NUBPL iron-transfer P-loop NTPase K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008073 400.0
TLS3_k127_5012185_2 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.0000000005388 70.0
TLS3_k127_5030386_0 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 452.0
TLS3_k127_5036209_0 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 609.0
TLS3_k127_5036209_1 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000006871 158.0
TLS3_k127_5036209_2 DEAD-like helicases superfamily - - - 0.00000000000000000000000003147 113.0
TLS3_k127_5050127_0 Alpha-amylase domain K01187 - 3.2.1.20 2.314e-216 684.0
TLS3_k127_5050127_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 301.0
TLS3_k127_5050127_2 Carbamoyltransferase C-terminus K00612 - - 0.00000000000000000000000000000000000000002476 156.0
TLS3_k127_5050127_3 PFAM ChaB family protein - - - 0.000000000000000000000000000000000004723 147.0
TLS3_k127_5050127_4 SNARE associated Golgi protein - - - 0.000000000000000000000000002983 124.0
TLS3_k127_5050127_5 AMP binding - - - 0.000000000000000000000001134 111.0
TLS3_k127_5075789_0 Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 346.0
TLS3_k127_5075789_1 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 310.0
TLS3_k127_5075789_2 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000001835 219.0
TLS3_k127_5075789_3 - - - - 0.0000000000001841 72.0
TLS3_k127_5096471_0 Thioredoxin reductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 391.0
TLS3_k127_5096471_1 Flavin-binding monooxygenase-like K03379,K18091 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0044237,GO:0044249,GO:0046483,GO:0055114,GO:0071704,GO:1901334,GO:1901336,GO:1901360,GO:1901362,GO:1901576 1.14.13.170,1.14.13.171,1.14.13.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000001924 263.0
TLS3_k127_5104687_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002778 269.0
TLS3_k127_5104687_1 ANTAR K22010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008401 261.0
TLS3_k127_5104687_2 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000003513 188.0
TLS3_k127_5104687_3 - - - - 0.00000000001127 74.0
TLS3_k127_5104687_4 Protein of unknown function (DUF3105) - - - 0.000334 50.0
TLS3_k127_5125720_0 Uncharacterised protein family (UPF0182) K09118 - - 0.00000000000000000000000000000000000000000000000000000000000002451 223.0
TLS3_k127_5125720_1 regulation of cell shape K04074 - - 0.00000000000000000000000000000000000000000008145 177.0
TLS3_k127_5130244_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 317.0
TLS3_k127_5130244_1 survival protein SurE K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009896 289.0
TLS3_k127_5132752_0 metal-dependent hydrolase of the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009996 477.0
TLS3_k127_5132752_1 acetyltransferase - - - 0.0000000001142 74.0
TLS3_k127_513765_0 Belongs to the aldehyde dehydrogenase family K00137 - 1.2.1.19 2.019e-247 787.0
TLS3_k127_513765_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 447.0
TLS3_k127_513765_2 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 426.0
TLS3_k127_513765_3 Aminotransferase K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 434.0
TLS3_k127_513765_4 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000195 245.0
TLS3_k127_5162631_0 PFAM FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 471.0
TLS3_k127_5162631_1 polysaccharide deacetylase - - - 0.00000000000000000000691 110.0
TLS3_k127_5162631_2 Hemerythrin HHE cation binding domain - - - 0.0000000000000004296 88.0
TLS3_k127_5162631_3 chitin binding K01183 - 3.2.1.14 0.000000000000004976 91.0
TLS3_k127_5162631_4 pyridoxamine 5-phosphate - - - 0.00000000171 64.0
TLS3_k127_5162631_5 Pfam:Pyridox_oxidase - - - 0.0000001179 61.0
TLS3_k127_5173775_0 phosphorelay sensor kinase activity K03406,K07673,K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000000000001957 201.0
TLS3_k127_5173775_1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07684 - - 0.000000000000000000000000000000000000000000000001407 177.0
TLS3_k127_5174377_0 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 580.0
TLS3_k127_5174377_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 414.0
TLS3_k127_5174377_2 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000000003399 147.0
TLS3_k127_5174377_3 Protein of unknown function (DUF3235) K21687,K21691 - - 0.000000000000002381 84.0
TLS3_k127_5176061_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00055 - 1.1.1.90 0.000000000000000000000000000000000000000000000000000000000000006533 221.0
TLS3_k127_5176061_1 - - - - 0.0000000000000000000000000000000000000001299 170.0
TLS3_k127_5176061_2 COG1233 Phytoene dehydrogenase and related proteins - - - 0.000877 44.0
TLS3_k127_5177316_0 F420-dependent oxidoreductase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 464.0
TLS3_k127_5177316_1 Fructosamine kinase - GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 - 0.0000000000000000000000000000000000000000000000000000004205 198.0
TLS3_k127_5177316_2 cytochrome p450 K16046 - 1.14.13.221 0.00000000000000000000000000000005789 127.0
TLS3_k127_5177316_3 Pfam:DUF385 - - - 0.000000000000000000000000000006098 122.0
TLS3_k127_5186602_0 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004772 559.0
TLS3_k127_5186602_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 391.0
TLS3_k127_5186602_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000003161 120.0
TLS3_k127_5187899_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000009904 250.0
TLS3_k127_5187899_1 Protein of unknown function (DUF3040) - - - 0.0000000000000000000002307 100.0
TLS3_k127_520542_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1957.0
TLS3_k127_5212835_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 3.082e-259 808.0
TLS3_k127_5212835_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 380.0
TLS3_k127_5212835_2 Bacterial phospho-glucose isomerase C-terminal SIS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 318.0
TLS3_k127_5212835_3 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.000000000000000000000002184 107.0
TLS3_k127_521721_0 gluconolactonase activity K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 355.0
TLS3_k127_521721_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K14441 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000001775 220.0
TLS3_k127_521721_2 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000003374 191.0
TLS3_k127_5218346_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009535 407.0
TLS3_k127_5218346_1 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 285.0
TLS3_k127_5218346_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000001748 230.0
TLS3_k127_5218346_3 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000002968 224.0
TLS3_k127_5218346_4 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000001375 203.0
TLS3_k127_5218346_5 hydrolase - - - 0.000000000000000000000000000000000000005149 151.0
TLS3_k127_5221165_0 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000000002279 184.0
TLS3_k127_5221165_1 BetI-type transcriptional repressor, C-terminal - - - 0.00000000000000000000000000002512 125.0
TLS3_k127_5221165_2 cell envelope-related transcriptional attenuator - - - 0.000000002587 66.0
TLS3_k127_5221165_3 Major facilitator superfamily - - - 0.00007036 55.0
TLS3_k127_5221835_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 558.0
TLS3_k127_5221835_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 315.0
TLS3_k127_5221835_2 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000001085 160.0
TLS3_k127_5221835_3 Domain of unknown function (DUF305) - - - 0.0000000000000000000000000000000000001656 149.0
TLS3_k127_5221835_4 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000000049 110.0
TLS3_k127_5223851_0 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 338.0
TLS3_k127_5223851_1 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003098 244.0
TLS3_k127_5223851_2 acyl-CoA dehydrogenase - - - 0.0000000294 56.0
TLS3_k127_5226632_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 359.0
TLS3_k127_5226632_1 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000002377 202.0
TLS3_k127_5226632_3 Ribosomal protein L33 K02913 - - 0.000000000000000000006986 92.0
TLS3_k127_5226632_4 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000001109 90.0
TLS3_k127_5227435_0 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000004487 269.0
TLS3_k127_5227435_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007373 252.0
TLS3_k127_5227435_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000006954 137.0
TLS3_k127_5227461_0 PFAM Cupin 2 conserved barrel domain protein K05913 - 1.13.11.41 0.00000000000000000000000000000000000000000000000000000009394 200.0
TLS3_k127_5227461_1 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000005793 189.0
TLS3_k127_5227461_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000006239 108.0
TLS3_k127_5227461_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000001558 74.0
TLS3_k127_5227461_4 lipolytic protein G-D-S-L family - - - 0.0000002546 62.0
TLS3_k127_5236453_0 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 597.0
TLS3_k127_5236453_1 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 472.0
TLS3_k127_5236453_2 Inositol monophosphatase family K01092,K05602 - 3.1.3.15,3.1.3.25 0.00000000000000000000000000000000000000000002485 173.0
TLS3_k127_5236453_3 AMP-binding enzyme C-terminal domain - - - 0.000000000007843 67.0
TLS3_k127_5237087_0 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 336.0
TLS3_k127_5237087_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000002877 197.0
TLS3_k127_5237087_2 iron dependent repressor - - - 0.00000000000000000000000000000000000000000001934 169.0
TLS3_k127_5237087_3 Inositol monophosphatase family K01082 - 3.1.3.7 0.000000000000000000000000000000000002363 138.0
TLS3_k127_5238637_0 Glycosyl hydrolases family 15 - - - 3.574e-221 703.0
TLS3_k127_5238637_1 Amino acid permease - - - 1.099e-211 676.0
TLS3_k127_5238637_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 449.0
TLS3_k127_5238637_3 PFAM TrkA-N domain protein K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000004953 233.0
TLS3_k127_5238637_4 Portal protein K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000001652 160.0
TLS3_k127_5238637_5 Histidine phosphatase superfamily (branch 1) - - - 0.00000000000000000000000000000000000000002018 158.0
TLS3_k127_5241043_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0 1047.0
TLS3_k127_5241043_1 NAD(P)-binding Rossmann-like domain K03379 - 1.14.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 331.0
TLS3_k127_5241043_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000001784 173.0
TLS3_k127_5241043_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000001476 137.0
TLS3_k127_5241043_4 Enoyl-CoA hydratase - - - 0.0000001316 53.0
TLS3_k127_5244288_0 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 534.0
TLS3_k127_5244288_1 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004371 248.0
TLS3_k127_5244585_0 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000001686 246.0
TLS3_k127_5244585_1 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000001395 192.0
TLS3_k127_5246973_0 Initiation factor 2 subunit family - - - 0.000000000000000000000000000000000000000000000000009014 190.0
TLS3_k127_5246973_1 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000000000000002245 172.0
TLS3_k127_5246973_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000001769 157.0
TLS3_k127_5266057_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 6.816e-288 906.0
TLS3_k127_5266057_1 Sulfate permease family K03321 - - 9.959e-209 664.0
TLS3_k127_5266057_2 Acyl-CoA synthetase (NDP forming) - - - 4.78e-196 666.0
TLS3_k127_5266057_3 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000004073 151.0
TLS3_k127_5266057_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000001362 89.0
TLS3_k127_5266476_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 535.0
TLS3_k127_5266476_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 514.0
TLS3_k127_5266476_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000007542 192.0
TLS3_k127_5266476_3 Protein of unknown function (DUF3151) - - - 0.000000000000000000000000000000000000000000001285 173.0
TLS3_k127_5266476_4 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000002684 174.0
TLS3_k127_5266476_5 Phosphoglycerate mutase - - - 0.00000000000000000000000000000000000000000343 162.0
TLS3_k127_5266476_6 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000003084 152.0
TLS3_k127_5266476_7 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000003144 63.0
TLS3_k127_5266476_8 - - - - 0.0000000291 61.0
TLS3_k127_5284773_0 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007312 473.0
TLS3_k127_5284773_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 452.0
TLS3_k127_5284773_2 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000005211 74.0
TLS3_k127_5298260_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1110.0
TLS3_k127_5298260_1 Alpha beta hydrolase K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000005315 188.0
TLS3_k127_5298260_2 Protein of unknown function (DUF2804) - - - 0.000000000000000000000000000000000004668 138.0
TLS3_k127_5299269_0 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000001248 248.0
TLS3_k127_5299269_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000001112 161.0
TLS3_k127_5303977_0 ABC transporter K02049,K10831,K15555 - 3.6.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 357.0
TLS3_k127_5303977_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 346.0
TLS3_k127_5303977_2 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000001352 180.0
TLS3_k127_5303977_3 Enoyl-(Acyl carrier protein) reductase K19548 - 1.1.1.385 0.0000000000002981 78.0
TLS3_k127_5304441_0 Starch synthase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 497.0
TLS3_k127_5304441_1 phosphoheptose isomerase K03271,K15669 - 2.7.7.71,5.3.1.28 0.00000000000000000000000000000000000000000000000000000002335 208.0
TLS3_k127_5304441_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000007954 130.0
TLS3_k127_5305214_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 5.643e-245 764.0
TLS3_k127_5305279_0 Helix-turn-helix domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001006 274.0
TLS3_k127_5305279_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000003021 195.0
TLS3_k127_5305279_2 PFAM CBS domain containing protein K06213 - - 0.0000000000000001095 92.0
TLS3_k127_5314826_0 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000007872 247.0
TLS3_k127_5314826_1 Methyltransferase domain - - - 0.00000000000000000000000000000252 121.0
TLS3_k127_5314826_2 GtrA-like protein - - - 0.000000000000000000002919 107.0
TLS3_k127_5331663_0 Pfam Sulfatase K01130 - 3.1.6.1 9.986e-233 732.0
TLS3_k127_5331663_1 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000002675 70.0
TLS3_k127_5336067_0 transferase activity, transferring alkyl or aryl (other than methyl) groups K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 304.0
TLS3_k127_5336067_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000006789 267.0
TLS3_k127_5336067_2 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001827 254.0
TLS3_k127_5336067_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000004216 201.0
TLS3_k127_5336067_4 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000009606 196.0
TLS3_k127_5336067_5 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000296 131.0
TLS3_k127_5336067_6 Helix-turn-helix domain - - - 0.000000000000008112 78.0
TLS3_k127_5336067_7 peptidase inhibitor activity - - - 0.0000000000000242 85.0
TLS3_k127_5343404_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 327.0
TLS3_k127_5343404_1 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006976 297.0
TLS3_k127_5347111_0 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.000000000000000000000000000000000001347 153.0
TLS3_k127_5347111_1 ROK family K00845,K00886 - 2.7.1.2,2.7.1.63 0.00000000000000000000001476 112.0
TLS3_k127_5347111_2 AAA domain - - - 0.0006389 51.0
TLS3_k127_5348258_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 392.0
TLS3_k127_5348258_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 295.0
TLS3_k127_5348258_2 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.000000000000000000000000000000000008746 148.0
TLS3_k127_5348258_3 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 0.00000000000000000000123 106.0
TLS3_k127_5348258_4 Methyltransferase domain - - - 0.0002789 50.0
TLS3_k127_5352731_0 beta-1,4-mannooligosaccharide phosphorylase - - - 7.66e-207 662.0
TLS3_k127_5352731_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 509.0
TLS3_k127_5352731_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 482.0
TLS3_k127_5352731_3 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 408.0
TLS3_k127_5352731_4 Cold shock protein K03704 - - 0.000000000000000000000000004723 111.0
TLS3_k127_5352731_5 Endoribonuclease L-PSP - - - 0.00001494 50.0
TLS3_k127_5358047_0 Proteasomal ATPase OB/ID domain K13527 - - 5.06e-269 838.0
TLS3_k127_5358047_1 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.000000000000000000000009618 102.0
TLS3_k127_5360490_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 535.0
TLS3_k127_5360490_1 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 338.0
TLS3_k127_5360490_2 Cytochrome c oxidase subunit III K02276,K02299 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000009116 227.0
TLS3_k127_5360490_3 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000006572 231.0
TLS3_k127_5360490_4 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000001145 64.0
TLS3_k127_5363327_0 HpcH/HpaI aldolase/citrate lyase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009539 487.0
TLS3_k127_5363327_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 453.0
TLS3_k127_5363327_2 phosphatidylinositol metabolic process K13671 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005249 295.0
TLS3_k127_5363327_3 PFAM Protein kinase K08282,K08884,K12132 - 2.7.11.1 0.00000000000335 76.0
TLS3_k127_5364054_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 484.0
TLS3_k127_5364054_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000003971 263.0
TLS3_k127_5364054_2 SMART Diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000001517 184.0
TLS3_k127_5367456_0 Ecdysteroid kinase - - - 0.000000000000000000000000000000000000000001063 170.0
TLS3_k127_5367456_1 Predicted metal-dependent hydrolase K07044 - - 0.00000000000000000000000000000000000001072 156.0
TLS3_k127_5394040_0 COG0366 Glycosidases K01187 - 3.2.1.20 2.078e-199 633.0
TLS3_k127_5394040_1 GTP-binding protein TypA K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 482.0
TLS3_k127_5394040_2 membrane transporter protein K07090 - - 0.0000000000000000000000002463 115.0
TLS3_k127_5395868_0 PFAM Amidohydrolase 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 500.0
TLS3_k127_5395868_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000001652 190.0
TLS3_k127_5395868_2 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000009457 119.0
TLS3_k127_5399711_0 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 342.0
TLS3_k127_5399711_1 Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme. - - - 0.00000000000000000000000000000000003239 156.0
TLS3_k127_5399711_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000001341 97.0
TLS3_k127_5415254_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 520.0
TLS3_k127_5415254_1 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000002934 215.0
TLS3_k127_5415254_2 Thiamine pyrophosphate enzyme, central domain K01652 GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030312,GO:0030976,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 0.000000000000000000000000000000000000000000000005858 173.0
TLS3_k127_5417788_0 drug exporters of the RND superfamily K06994 - - 4.816e-304 946.0
TLS3_k127_5417788_1 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 388.0
TLS3_k127_5423139_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 0.0 1339.0
TLS3_k127_5423139_1 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 1.613e-219 701.0
TLS3_k127_5423139_2 exo-alpha-(2->6)-sialidase activity K01186 - 3.2.1.18 0.00000000000000000000001477 101.0
TLS3_k127_5423139_3 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 0.0000000000000000000383 99.0
TLS3_k127_5432966_0 PFAM FAD linked oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 464.0
TLS3_k127_5432966_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 430.0
TLS3_k127_5432966_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 302.0
TLS3_k127_5432966_3 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 309.0
TLS3_k127_5432966_4 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000001002 226.0
TLS3_k127_5444531_0 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000001585 210.0
TLS3_k127_5444531_1 Transcriptional regulator - - - 0.0000000000000000000000007509 108.0
TLS3_k127_5444531_2 antisigma factor binding K04749 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000008787 74.0
TLS3_k127_5444531_3 CsbD-like - - - 0.0000000004143 63.0
TLS3_k127_545497_0 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 401.0
TLS3_k127_545497_1 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 370.0
TLS3_k127_545497_2 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 334.0
TLS3_k127_5464975_0 - K09957 - - 0.00000000000000000000000000000000000000000000000000000000001878 211.0
TLS3_k127_5464975_1 MerR, DNA binding K13639 - - 0.0000000000000000000000000000000000000000000000000000001925 202.0
TLS3_k127_5464975_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000001256 162.0
TLS3_k127_5502077_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 490.0
TLS3_k127_5502077_1 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007472 259.0
TLS3_k127_5502077_2 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000004738 194.0
TLS3_k127_5502077_3 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000003087 138.0
TLS3_k127_5505661_0 FAD linked K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 549.0
TLS3_k127_5505661_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.0000000000000000000000000002957 118.0
TLS3_k127_5505661_2 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000001855 72.0
TLS3_k127_551103_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 516.0
TLS3_k127_551103_1 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 501.0
TLS3_k127_5516288_0 Molybdenum Cofactor Synthesis C K03639 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 440.0
TLS3_k127_5516288_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000002816 251.0
TLS3_k127_5516288_2 Aldo/keto reductase family - - - 0.000000000000000000000000001716 117.0
TLS3_k127_5516288_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000000000000000003483 105.0
TLS3_k127_5516583_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 2.143e-194 611.0
TLS3_k127_5516583_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000002781 214.0
TLS3_k127_5516583_2 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000003845 210.0
TLS3_k127_5516583_3 Protein of unknown function (DUF520) K09767 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000323 209.0
TLS3_k127_5516583_4 phosphatidylinositol transporter activity - - - 0.00000000000000002417 88.0
TLS3_k127_5530638_0 glutamine synthetase K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 1.823e-300 927.0
TLS3_k127_5530638_1 RDD family - - - 0.00000000000000000000000000000005361 130.0
TLS3_k127_5559347_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006915 351.0
TLS3_k127_5559347_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090 - 0.00000000000000000000000000000000000000000000000006837 178.0
TLS3_k127_5559347_2 Glycosyl transferase, family 2 - - - 0.00007681 55.0
TLS3_k127_5565794_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 362.0
TLS3_k127_5565794_1 transcriptional regulator K22107 - - 0.00000000000000000000000000000000000000001464 160.0
TLS3_k127_5565794_2 Protein of unknown function (DUF983) - - - 0.00000000000000000000000000000000105 149.0
TLS3_k127_5565794_3 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000347 91.0
TLS3_k127_5565794_4 myo-inosose-2 dehydratase activity - - - 0.0003006 46.0
TLS3_k127_5573836_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 384.0
TLS3_k127_5573836_1 Transposase - - - 0.00000000000000000000000003818 119.0
TLS3_k127_5573836_2 - - - - 0.00001306 51.0
TLS3_k127_5576645_0 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 409.0
TLS3_k127_5576645_1 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 316.0
TLS3_k127_5576645_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000001642 173.0
TLS3_k127_5576645_3 - - - - 0.0000000000000000000000000002377 121.0
TLS3_k127_5576645_4 Cold-shock' K03704 - - 0.0008529 50.0
TLS3_k127_5581324_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 291.0
TLS3_k127_5581324_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000001704 250.0
TLS3_k127_5581324_2 membrane-anchored protein conserved in bacteria - - - 0.000000000000000000000000000000000000009922 159.0
TLS3_k127_5581324_3 overlaps another CDS with the same product name K16649 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008378,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016757,GO:0016758,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.4.1.287 0.00000000000007066 85.0
TLS3_k127_5586884_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 310.0
TLS3_k127_5589532_0 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 402.0
TLS3_k127_5589532_1 cellular modified histidine biosynthetic process - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006036 328.0
TLS3_k127_5589532_2 Beta-lactamase - - - 0.00000000000000000000006187 100.0
TLS3_k127_5610580_0 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 482.0
TLS3_k127_5610580_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008038 398.0
TLS3_k127_5610580_10 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000003013 91.0
TLS3_k127_5610580_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 365.0
TLS3_k127_5610580_3 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 336.0
TLS3_k127_5610580_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 329.0
TLS3_k127_5610580_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001606 282.0
TLS3_k127_5610580_6 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000000000000000000000000000000000011 166.0
TLS3_k127_5610580_7 Linear amide C-N hydrolases, choloylglycine hydrolase family - - - 0.000000000000000000000000000000000000001789 155.0
TLS3_k127_5610580_8 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases K03641 - - 0.0000000000000000000000000000000000006431 156.0
TLS3_k127_5610580_9 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000000000000000005022 123.0
TLS3_k127_5614352_0 Helix-hairpin-helix domain K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 399.0
TLS3_k127_5614352_1 YjbR - - - 0.000000000000000000000000000000000000000000007075 166.0
TLS3_k127_5619742_0 Fumarate reductase flavoprotein C-term K00278,K00767 GO:0008150,GO:0040007 1.4.3.16,2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 550.0
TLS3_k127_5619742_1 Quinolinate phosphoribosyl transferase, N-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 333.0
TLS3_k127_5619742_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 304.0
TLS3_k127_5619742_3 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003824 290.0
TLS3_k127_5623032_0 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 306.0
TLS3_k127_5629528_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 613.0
TLS3_k127_5629528_1 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes K00658,K09699 - 2.3.1.168,2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000001078 226.0
TLS3_k127_5634388_0 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000006608 230.0
TLS3_k127_5634388_1 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000936 111.0
TLS3_k127_5634388_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000002073 81.0
TLS3_k127_5634388_3 Transcriptional regulator - - - 0.00000000001635 70.0
TLS3_k127_5675511_0 tRNA threonylcarbamoyladenosine modification K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000001454 261.0
TLS3_k127_5675511_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000006612 192.0
TLS3_k127_5675511_2 peptidase S58, DmpA - - - 0.000000000000000000000000000000000000000000000001704 179.0
TLS3_k127_5675511_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000001311 139.0
TLS3_k127_5675511_4 FR47-like protein K03789 GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.00000000000000000000000000000005386 143.0
TLS3_k127_5675614_0 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 516.0
TLS3_k127_5675614_1 acyl-CoA dehydrogenase K22027 - 1.14.13.235 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 361.0
TLS3_k127_5675614_2 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000113 259.0
TLS3_k127_5740646_0 radical SAM K06871 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 583.0
TLS3_k127_5740646_1 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 459.0
TLS3_k127_5740646_2 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000028 274.0
TLS3_k127_5740646_3 binding-protein-dependent transport systems inner membrane component K02050,K15554 - - 0.000000000000000000000000000000000000000000000000000000000000000008203 232.0
TLS3_k127_5740646_4 membrane protein of uknown function UCP014873 - - - 0.0000000000000000000000000000000000000000000005138 177.0
TLS3_k127_5740646_5 Pyridoxal-dependent decarboxylase conserved domain K01580 - 4.1.1.15 0.00000000000000000002905 93.0
TLS3_k127_5746076_0 PFAM PKD domain containing protein - - - 9.827e-303 990.0
TLS3_k127_5746076_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000000000000000000000001748 234.0
TLS3_k127_5746076_2 biosynthesis protein K08252,K16692 - 2.7.10.1 0.0000000000000000000000000004147 126.0
TLS3_k127_5746076_3 Glycosyltransferase K12996 - - 0.0000000000000006696 78.0
TLS3_k127_5746076_4 - - - - 0.00000005286 63.0
TLS3_k127_5748200_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000005413 158.0
TLS3_k127_5748200_1 Sulfotransferase family - - - 0.00004024 51.0
TLS3_k127_575127_0 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 394.0
TLS3_k127_575127_1 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 299.0
TLS3_k127_575127_2 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.0000000000000000000000000000000000000000000000000000001173 196.0
TLS3_k127_575127_3 ATP-dependent DNA ligase - - - 0.000000000000000000000000000000000000000000003443 167.0
TLS3_k127_5768973_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 2.521e-230 737.0
TLS3_k127_5768973_1 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K05565,K14086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 578.0
TLS3_k127_5768973_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008991 389.0
TLS3_k127_5768973_3 AlkA N-terminal domain K13529 - 3.2.2.21 0.00000000000000000000000000000008168 125.0
TLS3_k127_5772465_0 transporter mgtE K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 491.0
TLS3_k127_5772465_1 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 355.0
TLS3_k127_5772465_2 - - - - 0.0000000000000000000005008 95.0
TLS3_k127_5776299_0 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000006812 165.0
TLS3_k127_5776299_1 Protein of unknown function (DUF459) K09795 - - 0.00000000000000000000003184 108.0
TLS3_k127_5776950_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 601.0
TLS3_k127_5776950_1 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01847 - 5.4.99.2 0.0000000000001251 71.0
TLS3_k127_5776950_2 Biotin carboxylase C-terminal domain K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 0.0000008019 51.0
TLS3_k127_578634_0 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000003912 231.0
TLS3_k127_578634_1 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000002241 126.0
TLS3_k127_578634_2 Protein of unknown function DUF58 - - - 0.00000000000004158 80.0
TLS3_k127_579272_0 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000499 492.0
TLS3_k127_579272_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 473.0
TLS3_k127_579272_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 319.0
TLS3_k127_579272_3 peroxidase activity K00435 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 306.0
TLS3_k127_579272_4 PFAM ExsB family protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003384 260.0
TLS3_k127_579272_5 Domain of unknown function (DUF427) - - - 0.000000000000000000000000000000000000000000000000000000000000000386 223.0
TLS3_k127_579272_6 - - - - 0.00000001045 59.0
TLS3_k127_579272_7 Nitrogen regulatory protein P-II K04751 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0006524 42.0
TLS3_k127_5793832_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 607.0
TLS3_k127_5793832_1 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 426.0
TLS3_k127_5809649_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01740,K01761 - 2.5.1.48,2.5.1.49,4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 525.0
TLS3_k127_5809649_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 525.0
TLS3_k127_5809649_2 N-6 DNA Methylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004747 282.0
TLS3_k127_5809649_3 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002102 252.0
TLS3_k127_5809649_4 Phosphoenolpyruvate phosphomutase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000001155 252.0
TLS3_k127_5809649_5 Domain of unknown function (DUF4328) - - - 0.0001709 52.0
TLS3_k127_5823167_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 341.0
TLS3_k127_5823167_1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001952 276.0
TLS3_k127_5823167_2 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001269 293.0
TLS3_k127_5823167_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002885 244.0
TLS3_k127_5823167_4 chain release factor K15034 - - 0.000000000000000000000000001247 117.0
TLS3_k127_5823167_5 GGDEF domain - - - 0.0000000000000000000000005293 113.0
TLS3_k127_5823167_6 Domain of unknown function (DUF3367) - - - 0.00002678 52.0
TLS3_k127_5826260_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K18688 - 6.2.1.42 2.464e-241 760.0
TLS3_k127_5826260_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 413.0
TLS3_k127_5826260_2 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 360.0
TLS3_k127_5833505_0 Tetrapyrrole (Corrin/Porphyrin) Methylases K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008024 278.0
TLS3_k127_5833505_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000004091 220.0
TLS3_k127_5833505_2 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000001842 121.0
TLS3_k127_5833505_3 Protein of unknown function, DUF488 - - - 0.000003302 53.0
TLS3_k127_5846260_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 2.951e-197 623.0
TLS3_k127_5846260_1 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 400.0
TLS3_k127_5846260_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 340.0
TLS3_k127_5846260_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000002154 266.0
TLS3_k127_5846260_4 Belongs to the peptidase S8 family K14645 - - 0.00000246 60.0
TLS3_k127_5846260_5 Acyltransferase family - - - 0.000003848 58.0
TLS3_k127_5850176_0 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 459.0
TLS3_k127_5850176_1 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001264 256.0
TLS3_k127_5850176_2 Acyl-CoA thioesterase K10805 - - 0.000000000000000000000000000000000000000000000000000000000000625 217.0
TLS3_k127_5854259_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.494e-218 704.0
TLS3_k127_5854259_1 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 555.0
TLS3_k127_5854259_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000001009 233.0
TLS3_k127_5861888_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 3.43e-206 646.0
TLS3_k127_5861888_1 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 532.0
TLS3_k127_5861888_2 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000001869 268.0
TLS3_k127_5865039_0 synthetase K00666 - - 4.662e-208 660.0
TLS3_k127_5865039_1 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000007029 197.0
TLS3_k127_5865039_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000398 140.0
TLS3_k127_5865472_0 Pup-ligase protein K20814 - 3.5.1.119 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 484.0
TLS3_k127_5865472_1 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation K13570 - - 0.000000000000000004582 85.0
TLS3_k127_5865472_2 Recombination endonuclease VII - - - 0.00000000000000003062 87.0
TLS3_k127_5913219_0 Fungal trichothecene efflux pump (TRI12) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 371.0
TLS3_k127_5913219_1 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 337.0
TLS3_k127_5913219_2 Pfam Pyridoxamine 5'-phosphate - - - 0.0000000000000000000000000176 110.0
TLS3_k127_5950121_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 424.0
TLS3_k127_5950121_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 318.0
TLS3_k127_5950121_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002186 283.0
TLS3_k127_5950121_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000094 287.0
TLS3_k127_5950121_4 His Kinase A (phosphoacceptor) domain K07636,K07768 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002394 277.0
TLS3_k127_5950121_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000007135 101.0
TLS3_k127_5950121_6 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000005384 49.0
TLS3_k127_5961068_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000000000000000000000000000000001203 219.0
TLS3_k127_5961068_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000003264 165.0
TLS3_k127_5961068_2 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000001696 163.0
TLS3_k127_5961068_3 MDMPI C-terminal domain - - - 0.00000000005437 71.0
TLS3_k127_5978285_0 - K07395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 314.0
TLS3_k127_5978285_1 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000008306 153.0
TLS3_k127_5978285_2 protein phosphatase 2C domain protein - - - 0.0000000000000000000000000000001378 136.0
TLS3_k127_5978285_3 GCN5-related N-acetyl-transferase K06975 - - 0.0000000000000004903 80.0
TLS3_k127_5991278_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 373.0
TLS3_k127_5991278_1 Acyl transferase domain K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000002752 265.0
TLS3_k127_5991278_2 reductase K00059,K11610 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0018454,GO:0019752,GO:0030497,GO:0032787,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046459,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0070402,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000002171 153.0
TLS3_k127_5992785_0 AAA ATPase domain - - - 0.00000000000000000002134 107.0
TLS3_k127_5992785_1 Diacylglycerol kinase catalytic domain - - - 0.000001235 51.0
TLS3_k127_5996888_0 Anthranilate synthase component I, N terminal region K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000001377 166.0
TLS3_k127_5996888_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000002285 156.0
TLS3_k127_5996888_2 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000003758 151.0
TLS3_k127_5996888_3 - K07018 - - 0.000000000000000001041 96.0
TLS3_k127_6003979_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 464.0
TLS3_k127_6003979_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 428.0
TLS3_k127_6003979_2 Methyltransferase domain - - - 0.00000000000000000000002054 113.0
TLS3_k127_6003979_3 Acyltransferase - - - 0.00000000000000000000007353 114.0
TLS3_k127_6030172_0 dihydrodipicolinate reductase K21672 - 1.4.1.12,1.4.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 341.0
TLS3_k127_6030172_1 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 324.0
TLS3_k127_6030172_2 Thioesterase-like superfamily K10805 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 312.0
TLS3_k127_6030172_3 RNA polymerase sigma-24 subunit, ECF subfamily - - - 0.0000003819 63.0
TLS3_k127_603022_0 Acyl-CoA dehydrogenase, C-terminal domain K00248,K14448 - 1.3.8.1,1.3.8.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 451.0
TLS3_k127_603022_1 Large extracellular alpha-helical protein - - - 0.00000000000000004865 95.0
TLS3_k127_6038281_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 5.327e-208 655.0
TLS3_k127_6038281_1 PFAM Amidohydrolase 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 292.0
TLS3_k127_6038281_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001461 278.0
TLS3_k127_6038281_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000001864 132.0
TLS3_k127_6042254_0 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits K16881 - 2.7.7.13,5.4.2.8 7.608e-275 868.0
TLS3_k127_6042254_1 Highly conserved protein containing a thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009767 278.0
TLS3_k127_6042254_2 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000005054 189.0
TLS3_k127_6042254_3 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000000000000000000000007768 192.0
TLS3_k127_6042254_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000435 175.0
TLS3_k127_6042254_5 Histidine triad (Hit) protein K02503 - - 0.00000000000000000000000000000000000000000000371 186.0
TLS3_k127_6042254_6 membrane protein (DUF2079) - - - 0.00000000000000000000000000000000001455 154.0
TLS3_k127_6042254_7 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000941 136.0
TLS3_k127_6042254_8 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000007631 118.0
TLS3_k127_6050353_1 Transcriptional regulatory protein, C terminal K07669,K07672 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 332.0
TLS3_k127_6050353_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 323.0
TLS3_k127_6050353_3 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 293.0
TLS3_k127_6050353_4 His Kinase A (phosphoacceptor) domain K07653 - 2.7.13.3 0.00000000000000000000000000000000000000000002474 179.0
TLS3_k127_6050353_5 efflux transmembrane transporter activity K02004 - - 0.000000000002582 71.0
TLS3_k127_6052333_0 PFAM Nucleotidyl transferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 358.0
TLS3_k127_6052333_1 Polysaccharide biosynthesis protein K01709 - 4.2.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 323.0
TLS3_k127_6059968_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 473.0
TLS3_k127_6059968_1 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 310.0
TLS3_k127_6059968_2 dTDP-4-dehydrorhamnose 3,5-epimerase activity K00067,K01710,K01790 - 1.1.1.133,4.2.1.46,5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 302.0
TLS3_k127_6059968_3 PFAM Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002747 276.0
TLS3_k127_6059968_4 Predicted membrane protein (DUF2142) - - - 0.00000000000000000000000000000000000000000000000000000001842 217.0
TLS3_k127_6059968_5 chitin binding - - - 0.00000000000000000000000000000000000000001184 158.0
TLS3_k127_6059968_6 DnaJ molecular chaperone homology domain - - - 0.00002002 55.0
TLS3_k127_6059968_7 transferase activity, transferring glycosyl groups K07011,K13659 - 2.4.1.264 0.00006949 48.0
TLS3_k127_6070376_0 UvrD-like helicase C-terminal domain K03657 GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 582.0
TLS3_k127_6070376_1 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 306.0
TLS3_k127_6070376_2 ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000001722 210.0
TLS3_k127_6070376_3 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000001562 186.0
TLS3_k127_6070376_4 Bacterial PH domain - - - 0.000000000000000000000000000000000000000000008169 170.0
TLS3_k127_6070376_5 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000000000004502 153.0
TLS3_k127_6070376_7 DSBA-like thioredoxin domain - - - 0.00000000000000000000000001734 115.0
TLS3_k127_6070376_8 in E. coli it is non essential for cell viability K07301 - - 0.00000003371 59.0
TLS3_k127_6070420_0 Rieske (2fe-2S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 426.0
TLS3_k127_6070420_1 acetoacetate decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 325.0
TLS3_k127_6070420_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000008366 57.0
TLS3_k127_6078858_0 ATPases associated with a variety of cellular activities K15738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 479.0
TLS3_k127_6079074_0 Aminotransferase class-V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 420.0
TLS3_k127_6079074_1 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009027 371.0
TLS3_k127_6079074_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000002093 168.0
TLS3_k127_6079074_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000002499 156.0
TLS3_k127_6079074_4 Rhomboid family K19225 - 3.4.21.105 0.000000000000000000000000000000000003309 141.0
TLS3_k127_6079074_5 tRNA methyl transferase K00566 - 2.8.1.13 0.000000000000868 80.0
TLS3_k127_6079074_6 - - - - 0.0000001174 57.0
TLS3_k127_6079074_7 Inositol monophosphatase family K01092 - 3.1.3.25 0.0003208 52.0
TLS3_k127_6081254_0 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 333.0
TLS3_k127_6081254_1 Sortase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003832 243.0
TLS3_k127_6081254_2 S-layer homology domain - - - 0.000000000000000000000000000000000000004715 168.0
TLS3_k127_6084325_0 ATP-dependent Clp protease K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 0.0 1229.0
TLS3_k127_6088789_0 Glycosyl transferases group 1 K13668 GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.346 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 326.0
TLS3_k127_6088789_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000004746 150.0
TLS3_k127_6088789_2 - - - - 0.000000000009894 75.0
TLS3_k127_6088789_3 AAA domain K01551 - 3.6.3.16 0.00000000001989 65.0
TLS3_k127_6089223_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 457.0
TLS3_k127_6089223_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 309.0
TLS3_k127_6089223_2 PFAM Phosphotransferase enzyme family - - - 0.00000000000000000000000000005617 120.0
TLS3_k127_6090611_0 Histidine kinase K00936 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 494.0
TLS3_k127_6090611_1 anion-transporting ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 497.0
TLS3_k127_6090611_2 Pfam Anion-transporting ATPase - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006477 393.0
TLS3_k127_6090611_3 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007682 266.0
TLS3_k127_6090611_4 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000002616 151.0
TLS3_k127_6090611_5 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000000000000000000000000002939 147.0
TLS3_k127_6090611_6 ATP-binding protein - - - 0.0000001177 61.0
TLS3_k127_6097306_0 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000008965 190.0
TLS3_k127_6097306_1 Tfp pilus assembly protein FimV - - - 0.0000002388 64.0
TLS3_k127_6099282_0 Protein of unknown function (DUF512) - - - 8.868e-202 646.0
TLS3_k127_6099282_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 372.0
TLS3_k127_6099282_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000003142 240.0
TLS3_k127_6103390_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 401.0
TLS3_k127_6103390_1 Protein of unknown function (DUF3089) - - - 0.0000000000000000000000000000001255 126.0
TLS3_k127_6115961_0 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 313.0
TLS3_k127_6115961_1 - - - - 0.00000000000000000000004497 111.0
TLS3_k127_6115961_2 PEP-utilising enzyme, mobile domain - - - 0.000000000000000000008621 100.0
TLS3_k127_6115961_3 SCP-2 sterol transfer family - - - 0.0005558 48.0
TLS3_k127_6123457_0 PFAM carboxyl transferase - - - 1.182e-254 801.0
TLS3_k127_6123457_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001332 281.0
TLS3_k127_6123457_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000007317 93.0
TLS3_k127_6130249_0 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 1.322e-248 779.0
TLS3_k127_6130249_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 435.0
TLS3_k127_6130249_2 Transketolase, pyrimidine binding domain K00615 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.2.1.1 0.00000000000000000000000000000000000000000000000005431 182.0
TLS3_k127_6130249_3 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000001144 141.0
TLS3_k127_6138774_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 2.5e-323 1008.0
TLS3_k127_6138774_1 TopoisomeraseII K02470 - 5.99.1.3 5.815e-279 872.0
TLS3_k127_6138774_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000002005 119.0
TLS3_k127_6138774_3 Protein of unknown function (DUF721) - - - 0.00000000000000003709 85.0
TLS3_k127_6138774_4 domain, Protein - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000002722 58.0
TLS3_k127_6144917_0 DEAD-like helicases superfamily K03724,K06877 - - 0.0 1841.0
TLS3_k127_6144917_1 Formamidopyrimidine-DNA glycosylase H2TH domain K05522 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.000000000000000000000000000000000000005731 151.0
TLS3_k127_6146871_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 441.0
TLS3_k127_6146871_1 Peptidase, M20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 433.0
TLS3_k127_6146871_2 lipid kinase activity - - - 0.000000000000000000000000303 117.0
TLS3_k127_6146871_3 DEAD-like helicases superfamily K03727 - - 0.000000000000000000000000841 107.0
TLS3_k127_6148895_0 Alcohol dehydrogenase GroES-associated - - - 0.00000000000000000000000000000000000000000003827 161.0
TLS3_k127_6148895_1 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000001807 137.0
TLS3_k127_6148895_2 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000245 112.0
TLS3_k127_6148895_4 Transcriptional regulator, TraR DksA family - - - 0.0000000000004919 76.0
TLS3_k127_6154008_0 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000001009 209.0
TLS3_k127_6154008_1 - - - - 0.000000000000000000002068 102.0
TLS3_k127_6157656_0 Uncharacterized protein family (UPF0051) K09014 - - 3.786e-242 756.0
TLS3_k127_6157656_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000006424 77.0
TLS3_k127_6162059_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472,K13015 - 1.1.1.136,1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 583.0
TLS3_k127_6162059_1 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000006911 84.0
TLS3_k127_6162225_0 Part of the ABC transporter FtsEX involved in cellular division K09811 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000002028 224.0
TLS3_k127_6162225_1 PFAM Peptidase M23 K21471 - - 0.000000000000000000000000000000000001244 153.0
TLS3_k127_6162225_2 ATPases associated with a variety of cellular activities K09812 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000005008 101.0
TLS3_k127_6170980_0 Elongator protein 3, MiaB family, Radical SAM - - - 4.268e-320 997.0
TLS3_k127_6170980_1 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 453.0
TLS3_k127_6170980_2 Cell division protein FtsA K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 375.0
TLS3_k127_6170980_3 Cell cycle protein K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 319.0
TLS3_k127_6170980_4 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.00000000000000000000000000000000000000000000000000000000001576 215.0
TLS3_k127_6170980_5 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.0000000000000000001289 96.0
TLS3_k127_6170980_6 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000001664 80.0
TLS3_k127_6181838_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 309.0
TLS3_k127_6181838_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 300.0
TLS3_k127_6181838_2 Bacterial transferase hexapeptide (six repeats) K02617 - - 0.00000000000000000000000000000000000000000000000000000000000000002656 228.0
TLS3_k127_6181838_3 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000001621 195.0
TLS3_k127_6181838_4 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000002719 152.0
TLS3_k127_6181838_5 endonuclease III K03575 - - 0.00000000000000000000000000001716 123.0
TLS3_k127_6181838_6 Protein of unknown function (DUF2752) - - - 0.0000000000000000001424 96.0
TLS3_k127_6182069_0 B12 binding domain K00548 - 2.1.1.13 0.0 1037.0
TLS3_k127_6182069_1 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000001013 235.0
TLS3_k127_6182069_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000001611 157.0
TLS3_k127_6184911_0 Pfam Sulfatase K01130 - 3.1.6.1 1.431e-255 810.0
TLS3_k127_6184911_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000001968 161.0
TLS3_k127_6184911_2 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000001536 132.0
TLS3_k127_6189941_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 393.0
TLS3_k127_6189941_1 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004786 276.0
TLS3_k127_6189941_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000001055 254.0
TLS3_k127_6189941_3 Siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000843 151.0
TLS3_k127_6192947_0 Belongs to the TPP enzyme family K01652 GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 1.493e-228 725.0
TLS3_k127_6192947_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 403.0
TLS3_k127_6192947_2 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002292 244.0
TLS3_k127_6192947_3 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000001147 250.0
TLS3_k127_6192947_4 - - - - 0.00000004275 66.0
TLS3_k127_6199536_0 glutamate synthase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 526.0
TLS3_k127_6199536_1 - - - - 0.000004039 55.0
TLS3_k127_6206765_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.071e-221 700.0
TLS3_k127_6206765_1 - - - - 0.0000497 55.0
TLS3_k127_6208163_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 454.0
TLS3_k127_6208163_1 VanW like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 327.0
TLS3_k127_6208163_2 diacylglycerol O-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000001249 227.0
TLS3_k127_6208163_3 dehydratase - - - 0.00000000000000000000000000000000000000000000004768 177.0
TLS3_k127_6212656_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000804 535.0
TLS3_k127_6212656_1 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 469.0
TLS3_k127_6212656_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000004685 216.0
TLS3_k127_6213603_0 transferase activity, transferring glycosyl groups - - - 6.474e-229 729.0
TLS3_k127_6217050_0 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 448.0
TLS3_k127_6217050_1 dioxygenase K11159 - - 0.000000000000000000000000000000000000000000000000000000005815 203.0
TLS3_k127_6217050_2 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000003444 183.0
TLS3_k127_6217050_3 WHG domain - - - 0.0000000000000000000000000000000000000001853 158.0
TLS3_k127_6217050_4 cytochrome p450 - - - 0.00000000000000000008944 89.0
TLS3_k127_6220527_0 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 427.0
TLS3_k127_6220527_1 Aminotransferase class I and II K00652,K01906 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030312,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.47,6.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 392.0
TLS3_k127_6220527_2 AAA domain - - - 0.000000000000000000000000000000000000000000000000003754 197.0
TLS3_k127_6220527_3 CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.00009766 53.0
TLS3_k127_6223229_0 2 iron, 2 sulfur cluster binding K00087,K03518,K07302 - 1.17.1.4,1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 319.0
TLS3_k127_6223229_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 303.0
TLS3_k127_6223229_2 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007619 273.0
TLS3_k127_6223229_3 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000000000000000000003056 134.0
TLS3_k127_6225070_0 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 475.0
TLS3_k127_6225070_1 Protein of unknown function (DUF2804) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001511 241.0
TLS3_k127_6225111_0 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 489.0
TLS3_k127_6225111_1 DUF1704 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008782 468.0
TLS3_k127_6225111_2 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 319.0
TLS3_k127_6225111_3 PFAM OsmC-like protein K04063 - - 0.00000000000000000000000000000000000000000000000000000000009308 207.0
TLS3_k127_6225111_4 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000000000000006057 147.0
TLS3_k127_6225111_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000008827 153.0
TLS3_k127_6225111_6 GDSL-like Lipase/Acylhydrolase - - - 0.0000005089 58.0
TLS3_k127_6228190_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 478.0
TLS3_k127_6228190_1 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 496.0
TLS3_k127_6228190_2 acyl-CoA hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009035 321.0
TLS3_k127_6228190_3 Sulfatase K01130 - 3.1.6.1 0.00000000000000000000001747 102.0
TLS3_k127_6238175_0 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000915 425.0
TLS3_k127_6238175_1 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 424.0
TLS3_k127_6238175_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000001189 188.0
TLS3_k127_6238175_3 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000004894 177.0
TLS3_k127_6238175_4 D-arabinono-1,4-lactone oxidase K00103 - 1.1.3.8 0.0000000000000000000000000002549 119.0
TLS3_k127_6240456_0 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 356.0
TLS3_k127_6240456_1 Belongs to the MenA family. Type 1 subfamily K02548 GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 316.0
TLS3_k127_6240456_2 alpha/beta hydrolase fold K08680 - 4.2.99.20 0.00000000000000000000000000000000000000000000000000000000000000000000001066 258.0
TLS3_k127_6240456_3 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.2.1.9 0.0000000000000000000000000000000000000000000000000000000701 199.0
TLS3_k127_6240456_4 PAS fold - - - 0.0000000005644 66.0
TLS3_k127_6243070_0 cytochrome p450 K16046 - 1.14.13.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 449.0
TLS3_k127_6243070_1 Mur ligase, middle domain protein - - - 0.00000004734 59.0
TLS3_k127_6243070_2 Acyltransferase family - - - 0.0000002897 61.0
TLS3_k127_6244783_0 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 602.0
TLS3_k127_6244783_1 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000000008369 228.0
TLS3_k127_6244783_2 tetR family - - - 0.00000000000000000000000000000000000000000000000007723 190.0
TLS3_k127_6244783_3 - - - - 0.0000000000000000000000000000000000000000000001043 175.0
TLS3_k127_6244783_4 Amidohydrolase - - - 0.00000000000000000000000000001679 117.0
TLS3_k127_6244783_5 Dehydrogenase - - - 0.000000000000000000000000000643 119.0
TLS3_k127_6244783_6 sequence-specific DNA binding K15773 - - 0.00000000001595 72.0
TLS3_k127_6244783_7 - - - - 0.0003991 53.0
TLS3_k127_6246567_0 Heat shock 70 kDa protein K04043 GO:0000302,GO:0000303,GO:0000305,GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016310,GO:0019222,GO:0019538,GO:0019899,GO:0030112,GO:0030162,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031975,GO:0031982,GO:0032268,GO:0032270,GO:0033554,GO:0034599,GO:0034614,GO:0035375,GO:0036211,GO:0040007,GO:0042221,GO:0042603,GO:0043170,GO:0043226,GO:0043227,GO:0043230,GO:0043388,GO:0043412,GO:0044044,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046677,GO:0046688,GO:0046777,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051099,GO:0051101,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070613,GO:0070887,GO:0071450,GO:0071451,GO:0071704,GO:0071944,GO:0080090,GO:0097691,GO:1901564,GO:1901700,GO:1901701,GO:1903317,GO:1903319,GO:1903561,GO:2000677,GO:2000679 - 3.699e-314 972.0
TLS3_k127_6246567_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 405.0
TLS3_k127_6246567_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000003979 129.0
TLS3_k127_6246567_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 331.0
TLS3_k127_6246567_3 of an ABC-type transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 289.0
TLS3_k127_6246567_4 Binding-protein-dependent transport system inner membrane component K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000001205 237.0
TLS3_k127_6246567_5 ammonium transporteR K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000001129 228.0
TLS3_k127_6246567_6 ABC transporter (Permease) K05846 - - 0.0000000000000000000000000000000000000000000001394 188.0
TLS3_k127_6246567_7 Nitrogen regulatory protein P-II K04751 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000001785 160.0
TLS3_k127_6246567_8 helix_turn_helix, mercury resistance K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000002275 142.0
TLS3_k127_6246567_9 PFAM ABC transporter related K05847 - - 0.00000000000000000000000000000001471 133.0
TLS3_k127_6260154_0 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 472.0
TLS3_k127_6260154_1 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000000000000000000000000000000000000000000000000002823 194.0
TLS3_k127_6260154_2 - - - - 0.0000000000000000000000000000000000000000000000004534 181.0
TLS3_k127_6264890_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 GO:0008150,GO:0040007 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 409.0
TLS3_k127_6264890_1 ArgK protein K07588 - - 0.000000000000000000000000000000002694 132.0
TLS3_k127_6264890_2 NifU-like domain - - - 0.0000000000000000000000000406 109.0
TLS3_k127_6267020_0 ADP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 532.0
TLS3_k127_626984_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 0.0 1859.0
TLS3_k127_626984_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.506e-309 963.0
TLS3_k127_626984_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002842 254.0
TLS3_k127_626984_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000005514 222.0
TLS3_k127_626984_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000002381 183.0
TLS3_k127_6270296_0 Bacterial extracellular solute-binding protein K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002036 274.0
TLS3_k127_6270296_1 Bacterial extracellular solute-binding protein K05813 - - 0.000000000000000000000000000000000000000000000000000000000000000000002922 247.0
TLS3_k127_6271033_0 D-arabinono-1,4-lactone oxidase K16653 - 1.1.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 568.0
TLS3_k127_6271033_1 UbiA prenyltransferase family K14136 - 2.4.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001361 286.0
TLS3_k127_6271033_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009772 276.0
TLS3_k127_6271033_3 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) K16652 - 1.1.1.333 0.000000000000000000000000000000000000000000000000000000000000000000000000000003552 274.0
TLS3_k127_6271033_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000003857 192.0
TLS3_k127_6271108_0 Thiolase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 545.0
TLS3_k127_6271108_1 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000003517 210.0
TLS3_k127_6271108_2 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000000000000000000007752 164.0
TLS3_k127_6273166_0 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 429.0
TLS3_k127_6273166_1 alcohol dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000118 271.0
TLS3_k127_6273166_2 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000001788 176.0
TLS3_k127_6285300_0 Belongs to the enoyl-CoA hydratase isomerase family K08299 - 4.2.1.149 0.000000000000000000000000000000000000000000000005837 182.0
TLS3_k127_6285300_2 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.0000002655 59.0
TLS3_k127_6289980_0 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 454.0
TLS3_k127_6289980_1 Xaa-Pro aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 450.0
TLS3_k127_6289980_2 Creatinase/Prolidase N-terminal domain K08688 - 3.5.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 306.0
TLS3_k127_6290978_0 Pfam:Zinicin_2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 388.0
TLS3_k127_6290978_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 289.0
TLS3_k127_6290978_2 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001214 281.0
TLS3_k127_6290978_3 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000007585 226.0
TLS3_k127_6290978_4 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000007477 214.0
TLS3_k127_6290978_5 Putative zinc-finger - - - 0.00000000000000000004572 92.0
TLS3_k127_6299121_0 CoA-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 360.0
TLS3_k127_6299121_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000366 280.0
TLS3_k127_6299121_2 PFAM EAL domain protein - - - 0.000000000000000000000000000000000000000000003178 185.0
TLS3_k127_6299121_3 dehydratase - - - 0.000000000000000000000000000000005251 133.0
TLS3_k127_6319167_0 E1-E2 ATPase K12952 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 477.0
TLS3_k127_6333302_0 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 520.0
TLS3_k127_6333302_1 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 323.0
TLS3_k127_6333302_2 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000001625 69.0
TLS3_k127_6365409_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 606.0
TLS3_k127_6365409_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000001386 74.0
TLS3_k127_6365409_2 Acetyltransferase (GNAT) domain K17840 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008080,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016020,GO:0016137,GO:0016139,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017001,GO:0017144,GO:0030647,GO:0030649,GO:0034069,GO:0044237,GO:0044248,GO:0044464,GO:0047921,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658 2.3.1.59 0.0004362 43.0
TLS3_k127_6369036_0 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 324.0
TLS3_k127_6369036_1 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000001041 220.0
TLS3_k127_6369036_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000008355 192.0
TLS3_k127_6369036_3 Protein of unknown function (DUF2469) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000005072 133.0
TLS3_k127_6369036_4 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000000000000000005574 124.0
TLS3_k127_6369036_5 Belongs to the UPF0109 family K06960 GO:0008150,GO:0040007 - 0.0000000000000000000000001367 113.0
TLS3_k127_6369036_6 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000001993 95.0
TLS3_k127_6369036_7 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.0000000000000001038 89.0
TLS3_k127_6370609_0 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000001436 219.0
TLS3_k127_6370609_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000001472 190.0
TLS3_k127_6370609_2 Acyltransferase family - - - 0.00000000000000000000000000000000008088 138.0
TLS3_k127_6385088_0 COG2015 Alkyl sulfatase and related hydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 332.0
TLS3_k127_6385088_1 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 297.0
TLS3_k127_6385088_2 PFAM monooxygenase FAD-binding K16022,K20943 - 1.14.13.219 0.0000000000000000000000000000000000000000000000000000000000000000000000002011 256.0
TLS3_k127_6385088_3 transcriptional regulator - - - 0.0000000000000000000000000000000000007176 148.0
TLS3_k127_6389051_0 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 521.0
TLS3_k127_6389051_1 chitin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 329.0
TLS3_k127_6389051_2 Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 325.0
TLS3_k127_6389051_3 PFAM glycoside hydrolase family 25 K07273 - - 0.0000000000000000000000000000000000000000000000000000000000003735 233.0
TLS3_k127_6389051_4 polysaccharide biosynthetic process K01992 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0008150,GO:0009987,GO:0044764,GO:0046812,GO:0051704 - 0.00000000000000000000000000000000000001254 154.0
TLS3_k127_6419288_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 1.129e-216 683.0
TLS3_k127_6432152_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009099 569.0
TLS3_k127_6432152_1 but contains a N-term CheY-like response regulator receiver domain and C-term adenylyl guanylyl cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 380.0
TLS3_k127_6432152_2 polysaccharide catabolic process K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 315.0
TLS3_k127_6432152_3 nuclease K01174,K07038 - 3.1.31.1 0.0000000000000000000000000000000002859 139.0
TLS3_k127_6432152_4 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000004272 145.0
TLS3_k127_6451666_0 - - - - 0.00000000000000000000000000000000000000000000000002451 188.0
TLS3_k127_6451666_1 DNA helicase - - - 0.00000000000000000000000000000000000000000000000005767 199.0
TLS3_k127_6451666_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000001485 164.0
TLS3_k127_6453439_0 Conserved Protein - - - 0.000000000000000000000000000000000000000000000000000000002097 216.0
TLS3_k127_6453439_1 - - - - 0.00000000000000000000000000002965 119.0
TLS3_k127_6456831_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.7.7.8 9.652e-207 655.0
TLS3_k127_6456831_1 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000002883 250.0
TLS3_k127_6467401_0 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 354.0
TLS3_k127_6467401_1 PFAM SMP-30 Gluconolaconase K20952 - - 0.00000000009463 70.0
TLS3_k127_6467401_2 Histidine kinase - - - 0.0007338 47.0
TLS3_k127_6471432_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 1.962e-206 652.0
TLS3_k127_6471432_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 462.0
TLS3_k127_6471432_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139,K01752,K01754 - 2.7.6.5,3.1.7.2,4.3.1.17,4.3.1.19 0.00000000000000000000000000000000000005945 152.0
TLS3_k127_6471432_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000004234 124.0
TLS3_k127_6471432_4 Histidine kinase - - - 0.000000000000000000002805 94.0
TLS3_k127_6486969_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000005222 244.0
TLS3_k127_6486969_1 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000007278 199.0
TLS3_k127_6491131_0 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000678 502.0
TLS3_k127_6491131_1 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 354.0
TLS3_k127_6491131_2 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000001617 163.0
TLS3_k127_6491131_3 Limonene-12-epoxide hydrolase K10533 - 3.3.2.8 0.00000000000000000000000000000000000000001972 156.0
TLS3_k127_6491131_4 Beta-lactamase - - - 0.00000000000000000000000000000000000005194 148.0
TLS3_k127_6508317_0 Creatinase/Prolidase N-terminal domain K01262,K01271 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 297.0
TLS3_k127_6508317_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006709 284.0
TLS3_k127_6508317_2 Catalyzes a trans-dehydration via an enolate intermediate K03786,K16021 - 4.2.1.10 0.0000000000000000000000000000000000002964 143.0
TLS3_k127_6508317_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000001296 128.0
TLS3_k127_6508317_4 Septum formation - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000001723 101.0
TLS3_k127_6516078_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 445.0
TLS3_k127_6516078_1 Carboxylesterase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009392 377.0
TLS3_k127_6516078_2 transmembrane transport K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 326.0
TLS3_k127_6524069_0 Ribonucleotide reductase, barrel domain K00525 - 1.17.4.1 8.404e-231 725.0
TLS3_k127_6524069_1 Lecithin:cholesterol acyltransferase - - - 0.000000000000000000000000000000000001114 150.0
TLS3_k127_6524069_2 Pyrimidine reductase, riboflavin biosynthesis K00082 - 1.1.1.193 0.000000000000000000000000000000000002969 158.0
TLS3_k127_6550089_0 Dak1_2 K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 376.0
TLS3_k127_6550089_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 304.0
TLS3_k127_6550089_2 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.00000000000000000000000000000000000000000000000000937 183.0
TLS3_k127_6550089_3 Ribosomal L28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000001942 115.0
TLS3_k127_6550089_4 Cold shock K03704 - - 0.0000000000000000000000008884 109.0
TLS3_k127_6567146_0 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 438.0
TLS3_k127_6567146_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000002963 204.0
TLS3_k127_6567146_2 Bacterial extracellular solute-binding protein K05813 - - 0.000000000004183 69.0
TLS3_k127_6577489_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 1.409e-252 799.0
TLS3_k127_6577489_1 Transmembrane secretion effector K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 364.0
TLS3_k127_6577489_2 replication factor c K02341,K02343,K09384 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007568 296.0
TLS3_k127_6577489_3 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000145 212.0
TLS3_k127_6577489_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000001083 209.0
TLS3_k127_6579174_0 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 331.0
TLS3_k127_6579174_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000004004 217.0
TLS3_k127_6579174_2 Protein of unknown function (DUF3097) - - - 0.00000000000000000000000000000006064 128.0
TLS3_k127_6585757_0 Elongation factor G, domain IV K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 1.113e-217 696.0
TLS3_k127_6585757_1 Glycosyltransferase Family 4 K08256 GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 436.0
TLS3_k127_6585757_2 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 332.0
TLS3_k127_6585757_3 Bacterial lipid A biosynthesis acyltransferase K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.265 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 300.0
TLS3_k127_6585757_4 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000003735 233.0
TLS3_k127_6585757_5 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000001136 230.0
TLS3_k127_6585757_6 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000003355 203.0
TLS3_k127_6585757_7 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000000000000000000000000002501 180.0
TLS3_k127_6585757_8 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.0000000000000000000000000000108 120.0
TLS3_k127_6592043_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 349.0
TLS3_k127_6592043_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008919 313.0
TLS3_k127_6592043_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000003277 71.0
TLS3_k127_6592043_3 Preprotein translocase subunit YajC K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000001467 65.0
TLS3_k127_6632588_0 Alanine racemase, N-terminal domain K06997 - - 0.000000000000000000000000000000000000000000000000001258 195.0
TLS3_k127_6632588_1 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000004504 158.0
TLS3_k127_6632588_2 Multi-copper polyphenol oxidoreductase laccase K05810 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944 - 0.0000000000000000000000000000000000002677 147.0
TLS3_k127_6632588_4 regulation of cell shape - - - 0.0000000001248 73.0
TLS3_k127_6657012_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 369.0
TLS3_k127_6657012_1 Short-chain alcohol dehydrogenase K16066 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.381 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005567 305.0
TLS3_k127_6657012_2 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000585 267.0
TLS3_k127_6657012_3 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000001218 179.0
TLS3_k127_6664319_0 Transcriptional regulator sugar kinase K00845,K00886 - 2.7.1.2,2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000447 282.0
TLS3_k127_6664319_1 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000001337 236.0
TLS3_k127_6671358_0 diacylglycerol O-acyltransferase K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 386.0
TLS3_k127_6671358_1 PD-(D/E)XK nuclease superfamily K07465 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006293 295.0
TLS3_k127_6671358_2 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001085 263.0
TLS3_k127_6671358_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000001373 216.0
TLS3_k127_6671358_4 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000000001976 154.0
TLS3_k127_6685532_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 2.71e-288 895.0
TLS3_k127_6685532_1 DNA-directed DNA polymerase activity K02340 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000008054 177.0
TLS3_k127_6685532_2 Binds directly to 16S ribosomal RNA K02968 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000003841 94.0
TLS3_k127_6692928_0 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 316.0
TLS3_k127_6692928_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 299.0
TLS3_k127_6692928_2 ATPases associated with a variety of cellular activities K15738 - - 0.0000000000000000000000000000000000000000378 156.0
TLS3_k127_6692928_3 - - - - 0.00000000000000000000000000000008204 134.0
TLS3_k127_6716834_0 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 331.0
TLS3_k127_6716834_1 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000198 268.0
TLS3_k127_6716834_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K00219,K01069 - 1.3.1.34,3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000027 234.0
TLS3_k127_6716834_3 WHG domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005439 228.0
TLS3_k127_6716834_4 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000001089 160.0
TLS3_k127_6716834_5 FxsA cytoplasmic membrane protein K07113 - - 0.000000000000000000000000000002127 127.0
TLS3_k127_6716834_6 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000000000000000000000004857 112.0
TLS3_k127_6750904_0 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 366.0
TLS3_k127_6750904_1 PFAM MaoC like domain - - - 0.000000000006823 71.0
TLS3_k127_6765279_0 acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000387 167.0
TLS3_k127_6765279_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000001903 61.0
TLS3_k127_6765279_2 Acyltransferase - - - 0.00000001414 59.0
TLS3_k127_6786110_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000008178 229.0
TLS3_k127_6786110_1 Sterol carrier protein - - - 0.00000000000000000000000000000000000000000000009621 173.0
TLS3_k127_6786110_2 Psort location CytoplasmicMembrane, score K12132 - 2.7.11.1 0.000000000000000002798 91.0
TLS3_k127_679379_0 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 440.0
TLS3_k127_679379_2 Putative RNA methylase family UPF0020 K07444 - - 0.000000000000000000000000000000002475 134.0
TLS3_k127_679379_3 dioxygenase activity - - - 0.000000000000000000007964 101.0
TLS3_k127_6831049_0 protoporphyrinogen oxidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 431.0
TLS3_k127_6831049_1 Phytanoyl-CoA dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001652 282.0
TLS3_k127_683400_0 PFAM bifunctional deaminase-reductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 378.0
TLS3_k127_683400_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000006577 206.0
TLS3_k127_683400_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000004769 207.0
TLS3_k127_6861853_0 ABC transporter transmembrane region K06147 - - 4.76e-233 736.0
TLS3_k127_688556_0 PFAM Glycosyl transferase, group 1 K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 454.0
TLS3_k127_688556_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000008722 150.0
TLS3_k127_688556_2 Heparinase II/III N-terminus - - - 0.00000000001335 71.0
TLS3_k127_688556_3 - - - - 0.0000003972 62.0
TLS3_k127_6888429_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000002131 207.0
TLS3_k127_6888429_1 GDP-mannose mannosyl hydrolase activity K08310 - 3.6.1.67 0.000000000000000000000000000000000000000000000000004171 185.0
TLS3_k127_6888429_2 IMP dehydrogenase activity - - - 0.0000000000000000000000000000002461 130.0
TLS3_k127_6888850_0 DNA ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 470.0
TLS3_k127_6888850_1 DNA ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 475.0
TLS3_k127_6888850_2 Fungalysin metallopeptidase (M36) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003505 299.0
TLS3_k127_6888850_3 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000006252 222.0
TLS3_k127_6888850_4 Transcriptional regulator - - - 0.000000004038 66.0
TLS3_k127_6888850_5 - - - - 0.00000002236 69.0
TLS3_k127_6888907_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 546.0
TLS3_k127_6888907_1 Cell division protein FtsQ K03589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.00002357 53.0
TLS3_k127_6894611_0 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000004504 213.0
TLS3_k127_6894611_1 Nitroreductase family - - - 0.0000000000000000000000000000000004514 141.0
TLS3_k127_6894611_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000002993 104.0
TLS3_k127_6901901_0 Bacterial regulatory proteins, tetR family - - - 0.0000000000003853 81.0
TLS3_k127_6901901_1 SMART Tetratricopeptide domain protein - - - 0.00000007175 64.0
TLS3_k127_6916001_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02021,K06147,K16786,K16787 - - 8.336e-203 649.0
TLS3_k127_6916001_1 ABC transporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 520.0
TLS3_k127_6916001_2 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 414.0
TLS3_k127_6916001_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007951 371.0
TLS3_k127_6919876_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 578.0
TLS3_k127_6919876_1 thiolester hydrolase activity K01990,K06889 GO:0008150,GO:0009987,GO:0051301 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001412 262.0
TLS3_k127_6919876_2 PFAM HhH-GPD family protein - - - 0.000000000000000000000000000000000000000000000000000000000000006676 222.0
TLS3_k127_6919876_4 - - - - 0.0000000001545 68.0
TLS3_k127_6921354_0 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 302.0
TLS3_k127_6921354_1 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001115 263.0
TLS3_k127_6935711_0 C-terminal, D2-small domain, of ClpB protein K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 9.687e-265 824.0
TLS3_k127_6935711_1 Polyprenyl synthetase K00805 - 2.5.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 335.0
TLS3_k127_6935711_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 295.0
TLS3_k127_6935711_3 Evidence 5 No homology to any previously reported sequences K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001069 274.0
TLS3_k127_6935711_4 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000004694 248.0
TLS3_k127_6935711_5 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000007444 93.0
TLS3_k127_6935711_6 Putative adhesin - - - 0.00002378 57.0
TLS3_k127_6943851_0 NIPSNAP family containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 326.0
TLS3_k127_6943851_1 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000434 201.0
TLS3_k127_6943851_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000002139 121.0
TLS3_k127_6943851_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000004887 119.0
TLS3_k127_6953645_0 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 475.0
TLS3_k127_6953645_1 alkaline phosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 420.0
TLS3_k127_6953645_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 311.0
TLS3_k127_6953645_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009961 305.0
TLS3_k127_6953645_4 DNA polymerase LigD polymerase domain K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005736 282.0
TLS3_k127_6953645_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000005353 219.0
TLS3_k127_6953645_6 HNH endonuclease - - - 0.0000000000002194 72.0
TLS3_k127_6961241_0 Pfam Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 595.0
TLS3_k127_6961241_1 Belongs to the aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 476.0
TLS3_k127_6961241_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003817 249.0
TLS3_k127_6972354_0 Circularly permuted ATP-grasp type 2 K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 540.0
TLS3_k127_6972354_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 419.0
TLS3_k127_6972354_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 324.0
TLS3_k127_6972354_3 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000677 301.0
TLS3_k127_6972354_4 Protein of unknown function (DUF2817) - - - 0.00000000000000000000000000000000000000000000000000000008948 211.0
TLS3_k127_6972354_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06991 - - 0.00000000000000000000000000000000000000000000000000009198 205.0
TLS3_k127_6972354_6 - - - - 0.000000000000000000000000000000000000000004348 165.0
TLS3_k127_6982038_0 C-terminal, D2-small domain, of ClpB protein K03695 - - 0.0 1060.0
TLS3_k127_6996335_0 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000002061 222.0
TLS3_k127_6996335_1 belongs to the sigma-70 factor family K03090 GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141 - 0.0000000000000000000000000000000000000000000007028 176.0
TLS3_k127_6996335_2 - - - - 0.0000000000000000000007841 101.0
TLS3_k127_7006736_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 462.0
TLS3_k127_7006736_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 374.0
TLS3_k127_7006736_2 Lipopolysaccharide biosynthesis protein K19424 - - 0.000000000000000000000000000000000000000000000001998 185.0
TLS3_k127_7009546_0 Carboxyl transferase domain - - - 2.751e-250 780.0
TLS3_k127_7009546_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 297.0
TLS3_k127_7009546_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 314.0
TLS3_k127_7009546_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 303.0
TLS3_k127_7009546_4 stage II sporulation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002083 263.0
TLS3_k127_7015911_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 5.14e-196 616.0
TLS3_k127_7015911_1 Belongs to the aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 580.0
TLS3_k127_7015911_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07812 - 1.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 332.0
TLS3_k127_7016034_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009253 385.0
TLS3_k127_7016034_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008764 333.0
TLS3_k127_7016034_2 - - - - 0.000000000000000000000000001709 117.0
TLS3_k127_7016034_3 SpoU rRNA Methylase family K00556 - 2.1.1.34 0.000000000000000000000008222 102.0
TLS3_k127_7017517_0 NADP-dependent oxidoreductase K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009177 403.0
TLS3_k127_7017517_1 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 326.0
TLS3_k127_7017517_2 Alkanesulfonate monooxygenase K04091 - 1.14.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000011 250.0
TLS3_k127_7017517_3 Formaldehyde-activating enzyme (Fae) K10713 - 4.2.1.147 0.000000000000000000000000000000000000000000000000006048 192.0
TLS3_k127_7017517_4 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000006047 162.0
TLS3_k127_7017517_5 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000005945 151.0
TLS3_k127_7035729_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 527.0
TLS3_k127_7035729_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 382.0
TLS3_k127_7040960_0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 454.0
TLS3_k127_7040960_1 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008163 303.0
TLS3_k127_7040960_2 Adenylate cyclase regulatory domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000004684 213.0
TLS3_k127_7040960_3 PFAM Glycoside hydrolase 15-related - - - 0.00000000000000000000000000000000000000000000000002493 206.0
TLS3_k127_7040960_4 nucleotidyltransferase activity K14941 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 0.0000000000000000000000000000000000000000004093 164.0
TLS3_k127_7040994_0 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 576.0
TLS3_k127_7040994_1 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 543.0
TLS3_k127_7040994_2 PFAM Chalcone and stilbene synthases, N-terminal domain K16167 - - 0.0000000000000000000000000000000000000000000000000000000000000000001222 246.0
TLS3_k127_7040994_3 SURF1 family - GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 - 0.000000000000000000000000000000000000000000000000000003026 200.0
TLS3_k127_7040994_5 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000001545 106.0
TLS3_k127_7066122_1 - - - - 0.0000000000001835 78.0
TLS3_k127_7066548_0 Heavy metal translocating P-type atpase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 401.0
TLS3_k127_7066548_1 Domain of unknown function (DUF305) - - - 0.0000000000000000000000000000000000000000000001878 177.0
TLS3_k127_7066548_2 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000001117 156.0
TLS3_k127_7066548_3 glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000000000000000000000000006203 125.0
TLS3_k127_7074413_0 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 550.0
TLS3_k127_7080675_0 Penicillin binding protein transpeptidase domain K05364 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 487.0
TLS3_k127_7080675_1 Serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 439.0
TLS3_k127_7080675_2 Peptidase C26 K01658,K01664 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007659 276.0
TLS3_k127_7080675_3 Cell cycle protein - - - 0.0000000000000000000000000000000000000001154 153.0
TLS3_k127_7103116_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009111 263.0
TLS3_k127_7103116_1 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000001275 125.0
TLS3_k127_7103116_2 - - - - 0.000000000000284 78.0
TLS3_k127_7113090_0 GTP-binding protein TypA K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000104 269.0
TLS3_k127_7113090_1 HNH nucleases - - - 0.000009918 57.0
TLS3_k127_7114844_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 588.0
TLS3_k127_7114844_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 415.0
TLS3_k127_7114844_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000002759 240.0
TLS3_k127_7121010_0 Regulator of chromosome condensation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008652 385.0
TLS3_k127_7121010_1 Bacterial extracellular solute-binding protein K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009742 278.0
TLS3_k127_7121010_2 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008455 225.0
TLS3_k127_7121010_3 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000005261 213.0
TLS3_k127_7121010_4 CHASE2 K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000146 223.0
TLS3_k127_7121010_5 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000004048 224.0
TLS3_k127_7121010_6 Protein of unknown function (DUF2834) - - - 0.0000000000000000000000000000000000000000001952 164.0
TLS3_k127_7121010_7 - - - - 0.00001629 57.0
TLS3_k127_7121010_8 PFAM FecR protein - - - 0.00002008 57.0
TLS3_k127_7124941_0 UvrD/REP helicase N-terminal domain - - - 0.0 1138.0
TLS3_k127_7124941_1 PD-(D/E)XK nuclease superfamily - - - 4.791e-250 797.0
TLS3_k127_7124941_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 320.0
TLS3_k127_7124941_3 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 302.0
TLS3_k127_7124941_4 Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 302.0
TLS3_k127_7124941_5 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000006818 198.0
TLS3_k127_7124941_6 Anti-sigma-K factor rskA - - - 0.00000000000000000000002966 110.0
TLS3_k127_7126909_0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 456.0
TLS3_k127_7128620_0 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 366.0
TLS3_k127_7128620_1 CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004904 260.0
TLS3_k127_7128620_2 ABC transporter related K06147 - - 0.00000000000000000000000000000000004757 147.0
TLS3_k127_7134038_0 Protein of unknown function, DUF255 K06888 - - 2.131e-235 750.0
TLS3_k127_7134038_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 474.0
TLS3_k127_7134038_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 302.0
TLS3_k127_7134038_3 Platelet-activating factor acetylhydrolase, isoform II - - - 0.0000000000000000000000000000000000002841 153.0
TLS3_k127_7134038_4 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.0000000000000000000001696 103.0
TLS3_k127_7139188_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 545.0
TLS3_k127_7139188_1 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 349.0
TLS3_k127_7139188_3 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001637 281.0
TLS3_k127_7139188_5 Antibiotic biosynthesis monooxygenase K06996,K21481 - 1.14.99.57 0.0000000000000000000000000008909 120.0
TLS3_k127_7139188_6 - - - - 0.000000000000000000000000003097 119.0
TLS3_k127_7139188_7 Type ii secretion system protein e K02283 - - 0.000005245 57.0
TLS3_k127_7158536_0 Domain of unknown function (DUF3367) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006725 600.0
TLS3_k127_7163234_0 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 340.0
TLS3_k127_7163234_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001188 268.0
TLS3_k127_7163234_2 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000000000000000000002312 249.0
TLS3_k127_7163234_3 PFAM Oxidoreductase FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000005151 185.0
TLS3_k127_7163234_4 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000005105 163.0
TLS3_k127_7168063_0 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000009227 179.0
TLS3_k127_7168063_2 Methionine biosynthesis protein MetW - - - 0.00004872 46.0
TLS3_k127_7171487_0 amidohydrolase - - - 3.468e-232 723.0
TLS3_k127_7171487_1 amidohydrolase - - - 3.831e-223 698.0
TLS3_k127_7171487_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 422.0
TLS3_k127_7171487_3 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 364.0
TLS3_k127_7171487_4 acetoacetate decarboxylase K01574 - 4.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009121 362.0
TLS3_k127_7171487_5 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000000002743 167.0
TLS3_k127_7179116_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 426.0
TLS3_k127_7179116_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676,K01678,K03780 - 4.2.1.2,4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 397.0
TLS3_k127_7183669_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 1.947e-230 727.0
TLS3_k127_7183669_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000003691 212.0
TLS3_k127_7183669_2 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02351,K07245 - - 0.00000000000000000001221 94.0
TLS3_k127_7189358_0 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 3.217e-250 799.0
TLS3_k127_7189358_1 UTRA K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000001066 237.0
TLS3_k127_7189358_2 Domain of unknown function (DUF4190) - - - 0.00000000002815 72.0
TLS3_k127_7189358_3 Methylamine utilisation protein MauE - - - 0.00002823 53.0
TLS3_k127_7191753_0 PFAM Xylose isomerase domain protein TIM barrel K01805 - 5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 508.0
TLS3_k127_7191753_1 xylulose kinase K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 389.0
TLS3_k127_7191753_2 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 0.00000000000000000000000000000000000000001355 158.0
TLS3_k127_7194372_0 Biotin carboxylase C-terminal domain K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 5.539e-258 806.0
TLS3_k127_7194372_1 UDP binding domain K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 546.0
TLS3_k127_7194372_2 Acyl-CoA dehydrogenase, C-terminal domain K00248,K11410 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 516.0
TLS3_k127_7194372_3 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 458.0
TLS3_k127_7194372_4 PFAM chorismate K01665,K03342 - 2.6.1.85,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 412.0
TLS3_k127_7194372_5 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 374.0
TLS3_k127_7194372_6 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 327.0
TLS3_k127_7194372_7 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004004 264.0
TLS3_k127_7194372_8 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000000000000000000000003155 236.0
TLS3_k127_7194372_9 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000001033 176.0
TLS3_k127_7215997_0 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 383.0
TLS3_k127_7215997_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 319.0
TLS3_k127_7215997_2 lysyltransferase activity K07027,K20468 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001661 259.0
TLS3_k127_7215997_3 Rieske 2Fe-2S - - - 0.00000000000000000000000000000000000000004087 154.0
TLS3_k127_72175_0 belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 494.0
TLS3_k127_72175_1 stress protein (general stress protein 26) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002601 232.0
TLS3_k127_7230065_0 dioxygenase K11159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 479.0
TLS3_k127_7230065_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 454.0
TLS3_k127_7230065_2 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 312.0
TLS3_k127_7230065_3 acyl-CoA hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005417 280.0
TLS3_k127_7230065_4 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009456 250.0
TLS3_k127_7230065_5 Transcriptional regulator - - - 0.00000000005044 71.0
TLS3_k127_7245289_0 Peptidase S9, prolyl oligopeptidase active site domain protein K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 407.0
TLS3_k127_7258529_0 Transketolase, pyrimidine binding domain K00615 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.2.1.1 1.017e-197 630.0
TLS3_k127_7258529_1 PFAM FIST C domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002216 276.0
TLS3_k127_7258529_2 transcriptional regulator K09017 - - 0.0000000000000000000000000000000000000000000000000000000001998 209.0
TLS3_k127_7265945_0 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 313.0
TLS3_k127_7265945_1 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000005428 220.0
TLS3_k127_727056_0 ABC transporter (Permease) K02004 - - 0.00000000000000000000000000000000000000000003806 172.0
TLS3_k127_727056_1 Bacterial regulatory proteins, tetR family K18939 - - 0.000000000000000000000000000000000004888 143.0
TLS3_k127_727056_2 Acetyltransferase (GNAT) family - - - 0.000131 49.0
TLS3_k127_7287170_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 610.0
TLS3_k127_7287170_1 Divergent 4Fe-4S mono-cluster K05337 - - 0.00000000000000000000000000157 112.0
TLS3_k127_7287170_2 Serine aminopeptidase, S33 - - - 0.00000000000000000000000001897 111.0
TLS3_k127_7287504_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 404.0
TLS3_k127_7287504_1 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.00000000000000000000000000000000000000000000000001871 185.0
TLS3_k127_7287504_2 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000006645 122.0
TLS3_k127_7288598_0 Thiamine pyrophosphate enzyme, central domain K00158 - 1.2.3.3 4.49e-295 920.0
TLS3_k127_7288598_1 PFAM Conserved region in glutamate synthase - - - 5.992e-254 793.0
TLS3_k127_7288598_10 dihydrodipicolinate reductase - - - 0.000000000000000000000000001312 122.0
TLS3_k127_7288598_12 Putative zinc-finger - - - 0.000000000000009597 78.0
TLS3_k127_7288598_13 DoxX - - - 0.0000000004433 72.0
TLS3_k127_7288598_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 597.0
TLS3_k127_7288598_3 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 594.0
TLS3_k127_7288598_4 Fe-S protein K07140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 290.0
TLS3_k127_7288598_5 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000112 222.0
TLS3_k127_7288598_6 Sigma-70 region 2 - - - 0.0000000000000000000000000000000000000000000000000000000005727 223.0
TLS3_k127_7288598_7 Transcriptional regulator - - - 0.000000000000000000000000000000000001895 144.0
TLS3_k127_7288598_8 - - - - 0.000000000000000000000000000000502 128.0
TLS3_k127_7288598_9 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000001252 118.0
TLS3_k127_7326039_0 belongs to the sigma-70 factor family K03090 - - 0.000000000000000000000000000000000000000000000000004484 191.0
TLS3_k127_7326039_1 PAS domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000002626 190.0
TLS3_k127_7326039_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000003258 148.0
TLS3_k127_7326039_3 SMART protein phosphatase 2C domain protein - - - 0.00000000000000003709 85.0
TLS3_k127_7326039_4 anti-sigma regulatory factor K04757 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036094,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 2.7.11.1 0.0000000001637 68.0
TLS3_k127_7329536_0 Sulfatase K01130 - 3.1.6.1 1.797e-258 801.0
TLS3_k127_7329536_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003526 248.0
TLS3_k127_7339354_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 454.0
TLS3_k127_7339354_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009101 449.0
TLS3_k127_7339354_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000002965 243.0
TLS3_k127_7339354_3 Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol K15520 - 2.3.1.189 0.0000000000000000000000000000000000000000000000000000001028 203.0
TLS3_k127_7339354_4 collagen metabolic process K01179 - 3.2.1.4 0.00000000000000000000000001898 122.0
TLS3_k127_7365063_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.272e-209 654.0
TLS3_k127_7365063_1 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001917 274.0
TLS3_k127_7371747_0 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 421.0
TLS3_k127_7371747_1 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 307.0
TLS3_k127_7371747_2 DNA helicase - - - 0.000000000000000000000000000000000001231 143.0
TLS3_k127_7393396_0 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 481.0
TLS3_k127_7393396_1 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 406.0
TLS3_k127_7403874_0 Beta propeller domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 321.0
TLS3_k127_7403874_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000009216 209.0
TLS3_k127_7403874_2 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000002447 188.0
TLS3_k127_740515_0 1-deoxy-D-xylulose-5-phosphate synthase K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008364 418.0
TLS3_k127_740515_1 Transketolase, pyrimidine binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 413.0
TLS3_k127_740515_2 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 368.0
TLS3_k127_740515_3 Cupin superfamily (DUF985) K09705 - - 0.000000000000000000000000000000000000000000000000000000000009774 211.0
TLS3_k127_740515_4 Trehalose utilisation K09992 - - 0.0000000000000000000000000000000000000000000000003992 186.0
TLS3_k127_740515_5 deazaflavin-dependent nitroreductase family protein - - - 0.0000000000000000000000000000000000000006263 154.0
TLS3_k127_7415754_0 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 363.0
TLS3_k127_7415754_1 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 306.0
TLS3_k127_7415754_2 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003024 262.0
TLS3_k127_7415754_3 acetyltransferase component of pyruvate dehydrogenase complex K00627,K00658 - 2.3.1.12,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000001209 230.0
TLS3_k127_7415754_4 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000267 209.0
TLS3_k127_7415754_5 membrane - - - 0.000000000000000000000000000000000000000000000000000000002076 210.0
TLS3_k127_7415754_6 Belongs to the thioredoxin family K00384,K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000003805 181.0
TLS3_k127_7415754_7 PFAM peptidase M50 - - - 0.0000000000000000000000001621 121.0
TLS3_k127_7415754_8 RDD family - - - 0.000000000000006584 81.0
TLS3_k127_7415754_9 Phosphopantetheine attachment site - - - 0.00001021 56.0
TLS3_k127_7440583_0 FG-GAP repeat protein - - - 0.0000000001931 73.0
TLS3_k127_7440583_1 Glycosyl transferase 4-like domain - - - 0.000003628 59.0
TLS3_k127_7466741_0 Pyridoxal-dependent decarboxylase conserved domain K01580,K01634 - 4.1.1.15,4.1.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 541.0
TLS3_k127_7466741_1 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.0001727 45.0
TLS3_k127_7529514_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 1.359e-238 750.0
TLS3_k127_7529514_1 Amidohydrolase - - - 1.396e-231 721.0
TLS3_k127_7529514_2 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 564.0
TLS3_k127_7529514_3 Dehydrogenase reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 407.0
TLS3_k127_7529514_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008746 416.0
TLS3_k127_7529514_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 353.0
TLS3_k127_7529514_6 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 349.0
TLS3_k127_7529514_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 307.0
TLS3_k127_7529514_8 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001629 269.0
TLS3_k127_7556573_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 4.383e-196 626.0
TLS3_k127_7556573_1 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002871 247.0
TLS3_k127_7556573_2 - - - - 0.00000004314 55.0
TLS3_k127_7584979_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007946 599.0
TLS3_k127_7584979_1 UTRA K03710 - - 0.000000000000000000000151 112.0
TLS3_k127_7589026_0 Integral membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 336.0
TLS3_k127_7589026_1 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000007688 226.0
TLS3_k127_7589026_2 Glycosyltransferase family 87 - - - 0.00003609 55.0
TLS3_k127_7676618_0 NeuB family K01654,K15898 - 2.5.1.56,2.5.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 376.0
TLS3_k127_7676618_1 WxcM-like, C-terminal - - - 0.000000000000000000000000000000000000000000000000000000001165 208.0
TLS3_k127_7676618_2 Sulfotransferase domain - - - 0.0000000000000000000000000000000004784 145.0
TLS3_k127_7676618_3 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000013 142.0
TLS3_k127_7676618_4 3-deoxy-manno-octulosonate-8-phosphatase activity K00983,K03270 - 2.7.7.43,3.1.3.45 0.000000000005849 67.0
TLS3_k127_7692163_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 382.0
TLS3_k127_7692163_1 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000009395 213.0
TLS3_k127_7692163_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000001982 169.0
TLS3_k127_7711688_0 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 546.0
TLS3_k127_7711688_1 dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 402.0
TLS3_k127_7711688_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 293.0
TLS3_k127_771349_0 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000161 258.0
TLS3_k127_771349_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000005448 126.0
TLS3_k127_771349_2 Protein conserved in bacteria K09764 - - 0.0002298 44.0
TLS3_k127_7736486_0 domain, Protein - - - 0.00000000222 71.0
TLS3_k127_774028_0 Anion-transporting ATPase - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 332.0
TLS3_k127_774028_1 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 320.0
TLS3_k127_7745157_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00140,K00823 - 1.2.1.18,1.2.1.27,2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 526.0
TLS3_k127_7745157_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 292.0
TLS3_k127_7745157_2 Dehydrogenase K00140 - 1.2.1.18,1.2.1.27 0.0000000000000001144 79.0
TLS3_k127_7752576_0 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 328.0
TLS3_k127_7752576_1 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000008888 252.0
TLS3_k127_7762223_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 350.0
TLS3_k127_7762223_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007168 244.0
TLS3_k127_7762223_2 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000001396 195.0
TLS3_k127_7762223_3 Ecdysteroid kinase - - - 0.000000000000000000000000000000000000000000001028 174.0
TLS3_k127_7762223_4 Short-chain dehydrogenase reductase sdr K19548 - 1.1.1.385 0.000000000000000000000000000000000000004214 148.0
TLS3_k127_7762223_5 4Fe-4S binding domain - - - 0.000000000000000000004037 96.0
TLS3_k127_7766321_0 Thiamine pyrophosphate enzyme, central domain K01652 GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030312,GO:0030976,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 7.083e-274 851.0
TLS3_k127_7766321_1 GMC oxidoreductase K03333 - 1.1.3.6 2.271e-254 826.0
TLS3_k127_7766321_2 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 501.0
TLS3_k127_7766321_3 Dehydratase family K01687 - 4.2.1.9 0.0000000000000000000000000001804 115.0
TLS3_k127_7778253_0 PFAM Copper amine oxidase K00276 - 1.4.3.21 2.118e-204 661.0
TLS3_k127_7778253_1 Short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005773 273.0
TLS3_k127_7778253_2 Aminopeptidase I zinc metalloprotease (M18) K01267 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.21 0.0000000000000000000000000000000000000000000000000000007653 196.0
TLS3_k127_7778253_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000001417 158.0
TLS3_k127_7784357_0 flavoprotein involved in K transport - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 3.209e-200 637.0
TLS3_k127_7784357_1 SnoaL-like polyketide cyclase - - - 0.000000000003263 75.0
TLS3_k127_7784357_2 oxidation-reduction process - - - 0.000000214 55.0
TLS3_k127_7789849_0 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001014 256.0
TLS3_k127_7789849_1 META domain K03668 - - 0.0000000000000000000000000000000000000000000000000000002052 208.0
TLS3_k127_7789849_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 - 3.5.4.1,3.5.4.33 0.0000000000000000000000000000000000000000000000000005273 187.0
TLS3_k127_7791086_0 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000001197 239.0
TLS3_k127_7791086_1 Jacalin-like lectin domain - - - 0.00000000000000000000000000000000000000000000000000000000006658 221.0
TLS3_k127_7793424_0 Domain of unknown function (DUF4162) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 330.0
TLS3_k127_7793424_1 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000001009 219.0
TLS3_k127_7793424_2 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000001961 206.0
TLS3_k127_7793424_3 Belongs to the UPF0312 family - - - 0.000000000000007998 80.0
TLS3_k127_7809559_0 Ftsk_gamma K03466 - - 3.445e-214 680.0
TLS3_k127_7809559_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000007303 124.0
TLS3_k127_781100_0 Activator of Hsp90 ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006409 242.0
TLS3_k127_781100_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000007196 217.0
TLS3_k127_781100_2 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000003201 175.0
TLS3_k127_781100_3 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000000205 145.0
TLS3_k127_7816694_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 5.456e-279 871.0
TLS3_k127_7816694_1 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000000000000000000000006492 109.0
TLS3_k127_7828839_0 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 555.0
TLS3_k127_7828839_1 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 302.0
TLS3_k127_7828839_2 Putative serine esterase (DUF676) - - - 0.0000000000000000000000000000000000000000592 164.0
TLS3_k127_7828839_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000001582 93.0
TLS3_k127_7829849_0 Putative diguanylate phosphodiesterase - GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009165,GO:0009166,GO:0009187,GO:0009190,GO:0009214,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0052621,GO:0055086,GO:0071111,GO:0071704,GO:0071944,GO:0090407,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 370.0
TLS3_k127_7829849_1 Mg-chelatase subunit ChlI K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009891 291.0
TLS3_k127_7839800_0 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 621.0
TLS3_k127_7839800_1 Belongs to the FGGY kinase family K00854,K00862,K00880 - 2.7.1.17,2.7.1.215,2.7.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 591.0
TLS3_k127_7839800_2 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 310.0
TLS3_k127_7839800_3 - - - - 0.00000000000446 79.0
TLS3_k127_7842554_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 2.61e-240 763.0
TLS3_k127_7842554_1 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 310.0
TLS3_k127_7842554_2 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000002393 207.0
TLS3_k127_7842554_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000009407 129.0
TLS3_k127_7842554_4 Glycosyl transferases group 1 - - - 0.00000000000000000008504 102.0
TLS3_k127_7842554_5 Asparagine synthase K01953 - 6.3.5.4 0.000000000001193 73.0
TLS3_k127_7842554_6 - - - - 0.00001216 59.0
TLS3_k127_7843612_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 304.0
TLS3_k127_7843612_1 Uncharacterised protein, DegV family COG1307 - - - 0.0001621 46.0
TLS3_k127_7847320_0 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 340.0
TLS3_k127_7847320_1 Peptidase family M50 - - - 0.0000000000000000000000000000001801 137.0
TLS3_k127_7851829_0 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 576.0
TLS3_k127_7851829_1 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 345.0
TLS3_k127_7851829_2 Protein of unknown function (DUF2630) - - - 0.000000000000000004824 86.0
TLS3_k127_7869569_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 553.0
TLS3_k127_7869569_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008676 408.0
TLS3_k127_7875650_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 1.688e-296 927.0
TLS3_k127_7875650_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 370.0
TLS3_k127_7875650_2 - - - - 0.000000000009369 70.0
TLS3_k127_7877063_0 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 1.31e-228 718.0
TLS3_k127_7877063_1 AMP-binding enzyme C-terminal domain K00666,K18687 - 6.2.1.41 2.333e-201 640.0
TLS3_k127_7877063_2 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 522.0
TLS3_k127_788059_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 456.0
TLS3_k127_788059_1 Guanylate kinase homologues. K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000008482 191.0
TLS3_k127_788059_2 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.6 0.000000000000000000001603 97.0
TLS3_k127_788059_3 integration host factor - - - 0.0000000000008017 68.0
TLS3_k127_7883453_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 443.0
TLS3_k127_7883453_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 295.0
TLS3_k127_7883453_10 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000005695 70.0
TLS3_k127_7883453_2 transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000000000000000000000000000000564 239.0
TLS3_k127_7883453_3 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001677 245.0
TLS3_k127_7883453_4 Protein of unknown function (DUF2587) - GO:0000502,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0016020,GO:0016043,GO:0019222,GO:0022607,GO:0022624,GO:0030162,GO:0030312,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032991,GO:0042176,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0044877,GO:0045732,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0060255,GO:0061136,GO:0065003,GO:0065007,GO:0070628,GO:0071840,GO:0071944,GO:0080090,GO:1901800,GO:1902494,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000002783 180.0
TLS3_k127_7883453_5 zinc ion binding K06204 - - 0.0000000000000000000000000000000000003384 147.0
TLS3_k127_7883453_6 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000008958 136.0
TLS3_k127_7883453_7 Large family of predicted nucleotide-binding domains - GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0070482,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.0000000000000000000000000000002862 128.0
TLS3_k127_7883453_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000001109 129.0
TLS3_k127_7883453_9 DNA polymerase alpha chain like domain K02337 - 2.7.7.7 0.0000000000004479 70.0
TLS3_k127_7914692_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000007144 263.0
TLS3_k127_7914692_1 synthase K00697 - 2.4.1.15,2.4.1.347 0.000000000000000000000000000000000000000000000000000000000000002885 225.0
TLS3_k127_7914692_2 trehalose biosynthetic process K01087 - 3.1.3.12 0.0000000000000000000000000000000000000005876 165.0
TLS3_k127_7914692_3 PFAM Glycosyl transferase, family 20 K00697 - 2.4.1.15,2.4.1.347 0.0000000000000000000000001207 109.0
TLS3_k127_7914692_4 Protein of unknown function (DUF3263) - - - 0.00000000000000000000004926 105.0
TLS3_k127_7914692_5 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000003172 49.0
TLS3_k127_7914692_6 LytR cell envelope-related transcriptional attenuator - - - 0.000799 49.0
TLS3_k127_7918865_0 Evidence 5 No homology to any previously reported sequences K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005084 279.0
TLS3_k127_7918865_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000351 237.0
TLS3_k127_7918865_2 Electron transfer flavoprotein FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000006122 221.0
TLS3_k127_7918865_3 Thioesterase superfamily - - - 0.000000000000000000000000000001919 126.0
TLS3_k127_7920787_0 FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 307.0
TLS3_k127_7920787_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 298.0
TLS3_k127_7920787_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000001523 190.0
TLS3_k127_7920787_3 Aminotransferase class-V K11717 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000663 193.0
TLS3_k127_7960624_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 363.0
TLS3_k127_7960624_1 Phosphoglycerate kinase K00927,K01803 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007409 284.0
TLS3_k127_7960624_2 Preprotein translocase SecG subunit K03075 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000001357 96.0
TLS3_k127_7960624_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000002404 79.0
TLS3_k127_796409_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 4.039e-263 828.0
TLS3_k127_796409_1 Trypsin K04771,K08372 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003816 284.0
TLS3_k127_796409_2 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000002745 159.0
TLS3_k127_796409_3 - - - - 0.000000000000000000000000005599 113.0
TLS3_k127_796409_4 CYTH - - - 0.0000000000000000000000002436 117.0
TLS3_k127_7972599_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 322.0
TLS3_k127_7972599_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000001966 250.0
TLS3_k127_7972599_2 Flavin containing amine oxidoreductase K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000005143 181.0
TLS3_k127_7972918_0 Cytochrome b(C-terminal)/b6/petD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 339.0
TLS3_k127_7972918_1 Rieske 2Fe-2S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 317.0
TLS3_k127_7972918_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000008546 109.0
TLS3_k127_7976544_0 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 362.0
TLS3_k127_7976544_1 TIGRFAM stage V sporulation protein E, cell division protein FtsW K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 330.0
TLS3_k127_7976544_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002157 281.0
TLS3_k127_7976544_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000003512 146.0
TLS3_k127_7985728_0 Lipase (class 2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008001 581.0
TLS3_k127_7985728_1 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009709 413.0
TLS3_k127_7985728_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000004092 151.0
TLS3_k127_7985728_3 Linear amide C-N hydrolases, choloylglycine hydrolase family - - - 0.000000000000000000000000000001468 131.0
TLS3_k127_8004052_0 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002819 258.0
TLS3_k127_8004052_1 - - - - 0.0000000000000000000001208 106.0
TLS3_k127_8004052_2 Multicopper oxidase K22349 - 1.16.3.3 0.0000000000000105 82.0
TLS3_k127_8006674_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1291.0
TLS3_k127_8006674_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000006517 86.0
TLS3_k127_8024280_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 469.0
TLS3_k127_8024280_1 60Kd inner membrane protein K03217 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000004142 229.0
TLS3_k127_8024280_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000001651 104.0
TLS3_k127_8024280_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000008716 100.0
TLS3_k127_8024280_4 Ribosomal protein L34 K02914 - - 0.0000000003201 68.0
TLS3_k127_8024280_5 ribonuclease P activity K03536,K08998 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.00000002113 62.0
TLS3_k127_8035269_0 Von Willebrand factor, type A - - - 1.793e-196 632.0
TLS3_k127_8035269_1 MviN-like protein K03980 GO:0003674,GO:0005215,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 353.0
TLS3_k127_8035269_2 - - - - 0.000000000000000000000000000000000000000000001852 173.0
TLS3_k127_8035269_3 Phage shock protein A K03969 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000006207 166.0
TLS3_k127_8043064_0 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 314.0
TLS3_k127_8043064_1 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004671 277.0
TLS3_k127_8043064_2 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000003786 166.0
TLS3_k127_8047505_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 584.0
TLS3_k127_8047505_1 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 512.0
TLS3_k127_8047505_2 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.00000000000000000000000000000000000437 142.0
TLS3_k127_8074351_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 528.0
TLS3_k127_8074351_1 DNA-binding transcription factor activity K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003254 254.0
TLS3_k127_8075544_0 Sap, sulfolipid-1-addressing protein - - - 0.0000000000000000000000000000000000000000000000000000000002599 207.0
TLS3_k127_8075544_1 - - - - 0.00000000000000000004652 97.0
TLS3_k127_8075544_2 response regulator - - - 0.0000000009318 68.0
TLS3_k127_8105348_0 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 481.0
TLS3_k127_8105348_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 338.0
TLS3_k127_8105348_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001033 270.0
TLS3_k127_8123467_0 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 463.0
TLS3_k127_8123467_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000001658 224.0
TLS3_k127_8123467_2 Platelet-activating factor acetylhydrolase, isoform II - - - 0.00000000000000000000000000000003786 136.0
TLS3_k127_8123467_3 protein with SCP PR1 domains - - - 0.000000000000001101 87.0
TLS3_k127_8123467_4 molybdenum cofactor guanylyltransferase activity K03752 - 2.7.7.77 0.00003588 48.0
TLS3_k127_8184824_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 391.0
TLS3_k127_8184824_1 Melibiase K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003273 292.0
TLS3_k127_8184824_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003273 269.0
TLS3_k127_8184824_3 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004537 259.0
TLS3_k127_8184824_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002336 246.0
TLS3_k127_8184824_5 Platelet-activating factor acetylhydrolase, isoform II - - - 0.0000000000000000000000000000000000000000000000000000000000003299 226.0
TLS3_k127_8184824_6 Transcriptional regulatory protein, C terminal - - - 0.000000000000000005395 88.0
TLS3_k127_8184824_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000004086 57.0
TLS3_k127_8201276_0 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 538.0
TLS3_k127_8220537_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005914 543.0
TLS3_k127_8220537_1 Peptidase C26 K01658,K07010 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000001055 258.0
TLS3_k127_8220537_2 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000008197 155.0
TLS3_k127_8220537_3 Mitochondrial biogenesis AIM24 - - - 0.00000000005502 68.0
TLS3_k127_8227991_0 DNA alkylation repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 312.0
TLS3_k127_8227991_1 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002432 279.0
TLS3_k127_8227991_2 collagen K19719,K19720,K19721 GO:0001101,GO:0001501,GO:0001654,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005581,GO:0005583,GO:0005588,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0007275,GO:0007423,GO:0008150,GO:0009653,GO:0009719,GO:0009887,GO:0009987,GO:0010033,GO:0010243,GO:0010470,GO:0012505,GO:0016043,GO:0022603,GO:0030198,GO:0030199,GO:0031012,GO:0031974,GO:0032501,GO:0032502,GO:0032991,GO:0042221,GO:0043062,GO:0043200,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043588,GO:0043933,GO:0044420,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045595,GO:0045596,GO:0045992,GO:0045995,GO:0046332,GO:0048513,GO:0048519,GO:0048523,GO:0048592,GO:0048731,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051093,GO:0051239,GO:0051241,GO:0051716,GO:0062023,GO:0065007,GO:0070013,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0071840,GO:0090596,GO:0097435,GO:0098643,GO:0098644,GO:0099080,GO:0099081,GO:0099512,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1903224,GO:1903225,GO:2000026,GO:2000542 - 0.000000000000000000000000000002909 132.0
TLS3_k127_8227991_3 CAAX protease self-immunity K07052 - - 0.000000000000000104 91.0
TLS3_k127_8255400_0 Glycosyl transferase 4-like domain K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 489.0
TLS3_k127_8255400_1 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000001586 192.0
TLS3_k127_8255400_2 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000002525 68.0
TLS3_k127_8256766_0 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000004211 241.0
TLS3_k127_8256766_1 TOBE domain - - - 0.0000000000000000000000000000000000009834 144.0
TLS3_k127_8256766_2 Bacterial extracellular solute-binding protein K02020 - - 0.000002034 58.0
TLS3_k127_8316928_0 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000007547 214.0
TLS3_k127_8316928_1 - - - - 0.0000000000007413 77.0
TLS3_k127_8340624_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 483.0
TLS3_k127_8340624_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 355.0
TLS3_k127_8340624_2 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000006352 243.0
TLS3_k127_8340624_3 Secreted repeat of unknown function - - - 0.0000000000000000000000000009825 119.0
TLS3_k127_8351310_0 Belongs to the FGGY kinase family K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 475.0
TLS3_k127_8351310_1 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 391.0
TLS3_k127_8351310_2 KR domain - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000104 269.0
TLS3_k127_8351310_3 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000000000000000000000000001221 233.0
TLS3_k127_8351310_4 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000005105 162.0
TLS3_k127_8351310_5 Domain of unknown function (DUF4870) K09940 - - 0.0000000000000000000000000000001089 130.0
TLS3_k127_8351310_6 Ring hydroxylating beta subunit - - - 0.00000000000000005334 88.0
TLS3_k127_8351310_7 Short-chain dehydrogenase reductase sdr - - - 0.0008146 43.0
TLS3_k127_8352685_0 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 344.0
TLS3_k127_8352685_1 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000006999 225.0
TLS3_k127_8352685_2 bis(5'-adenosyl)-triphosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000001546 210.0
TLS3_k127_8352685_3 sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000001722 210.0
TLS3_k127_8352685_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000003622 57.0
TLS3_k127_8456623_0 UvrD-like helicase C-terminal domain K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 2.643e-306 955.0
TLS3_k127_8456623_1 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 526.0
TLS3_k127_8456623_2 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000003926 201.0
TLS3_k127_8456623_3 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000003488 192.0
TLS3_k127_8456623_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.2.1.5 0.000000000000000000000000000000000000000001189 158.0
TLS3_k127_846226_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 532.0
TLS3_k127_846226_1 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000002611 240.0
TLS3_k127_846226_2 PFAM globin K06886 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000009027 150.0
TLS3_k127_846226_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000006919 118.0
TLS3_k127_846226_4 FabA-like domain K02372 - 4.2.1.59 0.0000000000000001729 88.0
TLS3_k127_8527754_0 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 441.0
TLS3_k127_8527754_1 PFAM Antibiotic biosynthesis monooxygenase K21481 - 1.14.99.57 0.0000000000000000000000000000000000000000001329 162.0
TLS3_k127_8527754_2 - - - - 0.000000000000007758 76.0
TLS3_k127_861002_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001039 278.0
TLS3_k127_861002_1 cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000378 226.0
TLS3_k127_861002_2 CcmB protein K02194 - - 0.0000000000000000000000000000000000000000000000000000000002762 213.0
TLS3_k127_861002_3 Cytochrome c-type biogenesis protein CcmF K02198 - - 0.00000000000000000000000000000000000002223 148.0
TLS3_k127_861002_4 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.0000000000000005353 87.0
TLS3_k127_868495_0 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 536.0
TLS3_k127_868495_1 Bacterial transcriptional repressor C-terminal - - - 0.000000000000000000000000000000000000000000000001102 183.0
TLS3_k127_875300_0 Alpha-amylase domain - - - 2.188e-207 656.0
TLS3_k127_885707_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 370.0
TLS3_k127_885707_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005961 235.0
TLS3_k127_885707_2 Belongs to the DegT DnrJ EryC1 family K13017 - 2.6.1.98 0.0000000000000000000000000000000001602 147.0
TLS3_k127_885707_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000001508 81.0
TLS3_k127_895940_0 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain K21023 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 409.0
TLS3_k127_895940_1 PFAM FAD linked oxidase domain protein K00803 - 2.5.1.26 0.00000000000000000000000000000000000000000000000000002933 192.0
TLS3_k127_895940_2 - K01611 - 4.1.1.50 0.00000000000000000000000000000000000001507 147.0
TLS3_k127_895940_3 Acyl-homoserine-lactone synthase - - - 0.00000000000000000005642 102.0
TLS3_k127_895940_4 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon - - - 0.000000002553 63.0
TLS3_k127_900485_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000001239 211.0
TLS3_k127_900485_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000001852 176.0
TLS3_k127_900485_2 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000001946 139.0
TLS3_k127_900485_3 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000002711 80.0
TLS3_k127_904746_0 protoporphyrinogen oxidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 328.0
TLS3_k127_904746_1 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000001928 214.0
TLS3_k127_904746_2 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000002976 168.0
TLS3_k127_904746_3 CoA binding domain - - - 0.000000000000000000000000000000000001026 147.0
TLS3_k127_904746_4 A circularly permuted ATPgrasp - - - 0.00000000000000000000000000000002473 127.0
TLS3_k127_91037_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 546.0
TLS3_k127_91037_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000007837 217.0
TLS3_k127_91037_2 - - - - 0.00000000000000000000003394 108.0
TLS3_k127_917209_0 ABC-type Fe3 transport system permease component K02011,K02063 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 594.0
TLS3_k127_917209_1 ABC transporter, periplasmic binding protein, thiB subfamily K02064 - - 0.00000000000000000000000000000235 122.0
TLS3_k127_918266_0 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000000000005216 204.0
TLS3_k127_918266_1 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000002342 174.0
TLS3_k127_918266_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000006851 175.0
TLS3_k127_918266_3 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000004276 137.0
TLS3_k127_918266_4 helix_turn_helix, mercury resistance - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000004231 110.0
TLS3_k127_918266_5 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.1.2.10 0.00000001712 57.0
TLS3_k127_918266_6 Bacterial regulatory proteins, tetR family - - - 0.000051 54.0
TLS3_k127_919231_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 347.0
TLS3_k127_919231_1 Cytochrome oxidase assembly protein K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001277 252.0
TLS3_k127_919231_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02298 - 1.10.3.10 0.000000000000000000000000000000000000000000000000000000009591 218.0
TLS3_k127_919231_3 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.0000000000000000000000000000000000003716 156.0
TLS3_k127_919231_4 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000005004 147.0
TLS3_k127_919231_5 - - - - 0.00000000000000001202 93.0
TLS3_k127_921126_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 4.942e-199 630.0
TLS3_k127_921126_1 PFAM Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 335.0
TLS3_k127_921126_2 AIR synthase related protein, C-terminal domain K01933 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016882,GO:0044424,GO:0044444,GO:0044464 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 306.0
TLS3_k127_921126_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000001048 219.0
TLS3_k127_921126_4 phosphatase activity K07025 - - 0.0000000000000000000000000000000000000000000000000001534 196.0
TLS3_k127_921898_0 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 406.0
TLS3_k127_921898_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000001907 238.0
TLS3_k127_921898_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000123 203.0
TLS3_k127_921898_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000007871 112.0
TLS3_k127_921898_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000004955 87.0
TLS3_k127_921898_5 amine dehydrogenase activity - - - 0.000007388 58.0
TLS3_k127_92862_0 Anion-transporting ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 403.0
TLS3_k127_92862_1 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000002254 153.0
TLS3_k127_92862_2 STAS domain - - - 0.0000000000000000000000000000000003545 134.0
TLS3_k127_92862_3 Belongs to the 'phage' integrase family - - - 0.0000000002149 65.0
TLS3_k127_94934_0 Cytochrome b subunit of the bc complex K03891 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 9.714e-315 969.0
TLS3_k127_94934_1 PFAM Rieske 2Fe-2S domain K03890 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 611.0
TLS3_k127_94934_2 PFAM cytochrome c K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 421.0
TLS3_k127_94934_3 PFAM cytochrome c oxidase subunit III K02276,K02299 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 337.0
TLS3_k127_954686_0 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002786 285.0
TLS3_k127_954686_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000118 223.0
TLS3_k127_95669_0 Mg-chelatase subunit ChlI K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 488.0
TLS3_k127_95669_1 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 305.0
TLS3_k127_95669_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000016 170.0
TLS3_k127_95669_3 beta-glucosidase activity K05350 - 3.2.1.21 0.0000000000000000000000000003239 115.0
TLS3_k127_968686_0 Ppx GppA phosphatase K01524 GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 459.0
TLS3_k127_968686_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000001786 229.0
TLS3_k127_968686_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000001277 171.0
TLS3_k127_984445_0 COG2217 Cation transport ATPase K17686 - 3.6.3.54 1.936e-307 954.0
TLS3_k127_993052_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000001068 247.0
TLS3_k127_993052_1 Copper chaperone PCu(A)C K09796 - - 0.000000000000000007756 91.0
TLS3_k127_993052_2 SCO1 SenC K07152 - - 0.00000000000001898 78.0
TLS3_k127_999104_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000004186 225.0
TLS3_k127_999104_1 DEAD DEAH box helicase K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000002312 177.0
TLS3_k127_999104_2 protein secretion K03116,K03117 GO:0003674,GO:0005215 - 0.00000001959 63.0