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Overview

ID MAG04045
Name TLS3_bin.22
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Blastocatellia
Order Pyrinomonadales
Family Pyrinomonadaceae
Genus PSRF01
Species
Assembly information
Completeness (%) 56.42
Contamination (%) 0.9
GC content (%) 55.0
N50 (bp) 4,182
Genome size (bp) 2,467,070

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2247

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1005447_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 299.0
TLS3_k127_1005447_1 ZIP Zinc transporter K07238,K11021,K16267 - - 0.00000000000000000000000000000000000000000000000000000000004374 214.0
TLS3_k127_1005447_2 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000004894 177.0
TLS3_k127_1005447_3 nucleotidyltransferase activity - - - 0.000000000000000000000001483 108.0
TLS3_k127_1005447_4 TPM domain K06872 - - 0.0000000000000000000005701 108.0
TLS3_k127_1005447_5 Penicillin-binding protein, transpeptidase domain protein K03587,K08384 - 3.4.16.4 0.0000105 52.0
TLS3_k127_1014538_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 575.0
TLS3_k127_1014538_1 argininosuccinate lyase K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 317.0
TLS3_k127_1014538_2 Mo-molybdopterin cofactor biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000022 272.0
TLS3_k127_1014538_3 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000008013 98.0
TLS3_k127_1014538_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000002602 49.0
TLS3_k127_1021987_0 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 338.0
TLS3_k127_1021987_1 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000004811 151.0
TLS3_k127_1021987_2 Bacterial regulatory proteins, luxR family - - - 0.000000000000000000000000000000000000005023 158.0
TLS3_k127_1021987_3 Two component regulator propeller - - - 0.0000000000001371 79.0
TLS3_k127_1025900_0 Leucine-rich repeat K13730 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008603 355.0
TLS3_k127_1025900_1 Protein of unknown function (DUF2847) - - - 0.0000000000000000003503 91.0
TLS3_k127_1025900_2 - K07004 - - 0.000000000000001187 86.0
TLS3_k127_1035887_0 ATPase associated with various cellular K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 380.0
TLS3_k127_1035887_1 Phosphate acyltransferases K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 342.0
TLS3_k127_1035887_2 Protein of unknown function DUF58 - - - 0.000000000000989 76.0
TLS3_k127_1035887_3 Pfam:N_methyl_2 - - - 0.0000007428 58.0
TLS3_k127_1041082_0 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 2.602e-262 818.0
TLS3_k127_1041082_1 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000368 123.0
TLS3_k127_1046543_0 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 497.0
TLS3_k127_1046543_1 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 487.0
TLS3_k127_1046543_2 Cytochrome c K08685 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284 417.0
TLS3_k127_1046543_3 - - - - 0.00000000000002561 85.0
TLS3_k127_1046543_4 peptidyl-tyrosine sulfation - - - 0.000001974 59.0
TLS3_k127_1046543_5 Beta-lactamase - - - 0.000002012 61.0
TLS3_k127_1056734_0 Two component regulator propeller - - - 1.083e-207 679.0
TLS3_k127_1056734_1 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 480.0
TLS3_k127_1056734_2 epoxide hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008991 423.0
TLS3_k127_1056734_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 308.0
TLS3_k127_1056734_4 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009226 300.0
TLS3_k127_1056734_5 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000001602 200.0
TLS3_k127_1056734_6 Histidine kinase - - - 0.000000000000000000002469 111.0
TLS3_k127_1056734_7 Transglutaminase-like superfamily - - - 0.00000000004086 69.0
TLS3_k127_1058867_0 CHASE3 domain - - - 1.02e-244 772.0
TLS3_k127_1058867_1 PFAM Response regulator receiver domain K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 454.0
TLS3_k127_1058867_2 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000001384 202.0
TLS3_k127_1058867_3 BON domain - - - 0.0000000000000000000000000000000000000000000000002923 183.0
TLS3_k127_1058867_4 Universal stress protein family - - - 0.00000000000000000000000000199 116.0
TLS3_k127_1064923_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 429.0
TLS3_k127_1064923_1 epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 304.0
TLS3_k127_1064923_2 Male sterility protein K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000003188 169.0
TLS3_k127_1064923_3 Putative esterase K07214 - - 0.0000000009317 72.0
TLS3_k127_1065963_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.644e-292 920.0
TLS3_k127_1065963_1 enoyl-coa hydratase carnithine racemase K15513 - 4.1.2.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 346.0
TLS3_k127_1065963_2 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 317.0
TLS3_k127_1067349_0 WD40 repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000141 284.0
TLS3_k127_1067349_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000009672 221.0
TLS3_k127_1073039_0 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009196 292.0
TLS3_k127_1073039_1 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000502 130.0
TLS3_k127_1073039_2 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000001054 121.0
TLS3_k127_1073039_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000003842 61.0
TLS3_k127_1073039_4 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000004684 57.0
TLS3_k127_1086333_0 PFAM Alanine dehydrogenase PNT, C-terminal domain K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 379.0
TLS3_k127_1086333_1 - - - - 0.000000000000000002009 88.0
TLS3_k127_1086333_2 Phage integrase family - - - 0.000000000000002824 77.0
TLS3_k127_109068_0 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 609.0
TLS3_k127_109068_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0046686,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 354.0
TLS3_k127_109068_2 Xylose isomerase-like TIM barrel K06606 - 5.3.99.11 0.00000000000000000000000000000000000000000000000000000000000002746 224.0
TLS3_k127_1093961_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 307.0
TLS3_k127_1093961_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.0000000000000000000000000000000000000000000000000000000003021 209.0
TLS3_k127_111327_0 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 2.574e-263 824.0
TLS3_k127_111327_1 Belongs to the aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 383.0
TLS3_k127_1125989_0 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000003354 178.0
TLS3_k127_1125989_1 Zn peptidase K21686 - - 0.000000000000000000000000001444 119.0
TLS3_k127_1125989_2 sequence-specific DNA binding - - - 0.00008729 50.0
TLS3_k127_112766_0 Soluble lytic murein transglycosylase-like protein - - - 0.000000000000000000000000000000000006425 148.0
TLS3_k127_112766_1 - - - - 0.0000001168 62.0
TLS3_k127_113966_0 SpoIVB peptidase S55 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 372.0
TLS3_k127_113966_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.00000000000000000000000000002653 126.0
TLS3_k127_113966_2 Alpha beta hydrolase - - - 0.00001554 55.0
TLS3_k127_1140828_0 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 451.0
TLS3_k127_1140828_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000001011 159.0
TLS3_k127_1140828_2 von Willebrand factor, type A - - - 0.0000000000000000000006732 108.0
TLS3_k127_1140828_3 PFAM plasmid - - - 0.0000000009636 63.0
TLS3_k127_1142183_0 Gluconolactonase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 327.0
TLS3_k127_1142183_1 D-proline reductase, PrdB subunit K10794 - 1.21.4.1 0.0000000000000000001316 98.0
TLS3_k127_1142183_3 Domain of unknown function (DUF309) K09763 - - 0.0000001262 57.0
TLS3_k127_1144401_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008475 338.0
TLS3_k127_1144401_1 Phosphoribosyl transferase domain K00760,K15780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000003245 230.0
TLS3_k127_1144401_2 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.00000000000000000005348 101.0
TLS3_k127_1144401_3 PFAM plasmid - - - 0.00000000007678 66.0
TLS3_k127_1144401_4 Putative addiction module component - - - 0.00002409 48.0
TLS3_k127_1173816_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 342.0
TLS3_k127_1173816_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 327.0
TLS3_k127_1173816_2 - - - - 0.000000000000000000000001739 106.0
TLS3_k127_1173816_3 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000669 95.0
TLS3_k127_1181189_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000008012 187.0
TLS3_k127_1181189_1 Mo-molybdopterin cofactor metabolic process K03148,K03636,K21029,K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.73,2.7.7.80,2.8.1.11 0.000000000000000000000000000289 118.0
TLS3_k127_1181189_2 - - - - 0.0000000000000000000000002838 117.0
TLS3_k127_1186602_0 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000009027 181.0
TLS3_k127_1186602_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000002655 140.0
TLS3_k127_1186602_2 Protein of unknown function (DUF2662) - - - 0.0001761 52.0
TLS3_k127_119315_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1084.0
TLS3_k127_119315_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000001637 248.0
TLS3_k127_119315_2 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000001676 76.0
TLS3_k127_119617_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 337.0
TLS3_k127_1197486_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 466.0
TLS3_k127_1197486_1 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001728 279.0
TLS3_k127_1197486_2 PAS domain containing protein K02030 - - 0.000000000000000000000000000000000000000000005645 184.0
TLS3_k127_1197486_3 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000004754 147.0
TLS3_k127_1197486_4 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000001133 123.0
TLS3_k127_1205021_0 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 428.0
TLS3_k127_1205021_1 phosphorelay sensor kinase activity K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000002024 188.0
TLS3_k127_1212623_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002545 263.0
TLS3_k127_1212623_1 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000009781 225.0
TLS3_k127_1212623_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000001673 219.0
TLS3_k127_1212623_3 Polysaccharide biosynthesis protein K12454 - 5.1.3.10 0.000000000000000000000000006587 121.0
TLS3_k127_1232489_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000002245 229.0
TLS3_k127_1232489_1 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000185 190.0
TLS3_k127_1232489_2 Branched-chain amino acid transport K01996 - - 0.000000000001625 69.0
TLS3_k127_1235288_0 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 385.0
TLS3_k127_1235288_1 SnoaL-like domain K06893 - - 0.000000000000000000000000000000000007174 140.0
TLS3_k127_1235288_2 Thioredoxin-like - - - 0.00000000000000000000001642 112.0
TLS3_k127_1235288_3 Belongs to the ompA family K03640 - - 0.00003416 54.0
TLS3_k127_1249195_0 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 546.0
TLS3_k127_1249195_1 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008023 407.0
TLS3_k127_1249195_2 lysyltransferase activity K07027 - - 0.00001576 56.0
TLS3_k127_1253672_0 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 296.0
TLS3_k127_1253672_1 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000005308 159.0
TLS3_k127_1253672_3 response to heat K07090 - - 0.00000000000000000000005862 100.0
TLS3_k127_1253672_4 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000001561 64.0
TLS3_k127_1305792_0 glycosyl transferase group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 408.0
TLS3_k127_1305792_1 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004976 240.0
TLS3_k127_1321716_0 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 445.0
TLS3_k127_1321716_1 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000004346 226.0
TLS3_k127_1321716_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000009565 130.0
TLS3_k127_1321716_3 MgtE intracellular N domain - - - 0.00000000000000000000000000008733 119.0
TLS3_k127_1354945_0 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.000000000000000000000000000000000000001046 153.0
TLS3_k127_1354945_1 iron ion homeostasis - - - 0.00005168 56.0
TLS3_k127_1359980_0 PFAM glycoside hydrolase family 1 K05350 - 3.2.1.21 3.8e-224 703.0
TLS3_k127_1359980_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000006276 194.0
TLS3_k127_1359980_2 redox protein, regulator of disulfide bond formation K04063 - - 0.00000000000000000000002093 102.0
TLS3_k127_1403772_0 periplasmic or secreted lipoprotein - - - 0.00000000000000000006223 93.0
TLS3_k127_1403772_1 Tetratricopeptide repeat - - - 0.00007774 55.0
TLS3_k127_1403912_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 469.0
TLS3_k127_1403912_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002129 292.0
TLS3_k127_1403912_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000002055 205.0
TLS3_k127_1403912_3 Winged helix DNA-binding domain K09927 - - 0.0000000000000000000000000000000000000005002 150.0
TLS3_k127_1419106_0 E1-E2 ATPase - - - 0.0000000000000000000000000003061 114.0
TLS3_k127_1419106_1 serine threonine protein kinase - - - 0.00005948 56.0
TLS3_k127_1420012_0 PFAM NUDIX hydrolase - - - 0.0000000000000002178 91.0
TLS3_k127_1420012_1 Methionine biosynthesis protein MetW K00570 - 2.1.1.17,2.1.1.71 0.0000000000000003499 88.0
TLS3_k127_1420012_2 Glucose-1-phosphate thymidyltransferase K00973 - 2.7.7.24 0.00000000001315 76.0
TLS3_k127_1420012_3 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000002758 63.0
TLS3_k127_143355_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1213.0
TLS3_k127_143355_1 PFAM Amino acid permease K03294 - - 6.31e-222 705.0
TLS3_k127_143355_2 5TM C-terminal transporter carbon starvation CstA K06200 - - 1.206e-215 685.0
TLS3_k127_143355_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 564.0
TLS3_k127_143355_4 PFAM BioY protein K03523 - - 0.000000000000000000000000000000000000000008459 160.0
TLS3_k127_143355_5 PFAM Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000002834 143.0
TLS3_k127_143355_6 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.0000000000000000000000000000002698 127.0
TLS3_k127_143355_7 AMP binding - - - 0.000000000000000006218 94.0
TLS3_k127_143355_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000003619 60.0
TLS3_k127_1450621_0 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005016 261.0
TLS3_k127_1450621_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000003018 137.0
TLS3_k127_1450621_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00001476 48.0
TLS3_k127_146065_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 367.0
TLS3_k127_146065_1 Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000736 179.0
TLS3_k127_147601_0 SMART PDZ DHR GLGF domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000004914 237.0
TLS3_k127_147601_1 Enoyl-CoA hydratase/isomerase K01715,K13767 GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000002713 226.0
TLS3_k127_1487731_0 transferase activity, transferring glycosyl groups K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 340.0
TLS3_k127_1487731_1 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003036 276.0
TLS3_k127_1487731_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004751 262.0
TLS3_k127_1487731_3 Peptidase family M9 N-terminal K01387 - 3.4.24.3 0.000000000000004048 90.0
TLS3_k127_1487731_4 ig-like, plexins, transcription factors - - - 0.000002517 60.0
TLS3_k127_1487731_5 Endonuclease/Exonuclease/phosphatase family - - - 0.0001033 54.0
TLS3_k127_1487731_6 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0001501 55.0
TLS3_k127_1492383_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 487.0
TLS3_k127_1492383_1 - - - - 0.0000000347 58.0
TLS3_k127_149578_0 FAD linked oxidase domain protein - - - 3.605e-208 655.0
TLS3_k127_149578_1 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 465.0
TLS3_k127_149578_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000005989 126.0
TLS3_k127_149578_3 AAA ATPase domain - - - 0.0000000000001051 72.0
TLS3_k127_149578_4 AMP binding - - - 0.00000000001313 76.0
TLS3_k127_149578_5 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000003614 70.0
TLS3_k127_149578_6 DNA-templated transcription, initiation K03088 - - 0.0003359 49.0
TLS3_k127_1499139_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 360.0
TLS3_k127_1499139_1 Domain of unknown function (DUF4956) - - - 0.0000000000002602 79.0
TLS3_k127_1512058_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009743 270.0
TLS3_k127_1512058_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000008001 145.0
TLS3_k127_1564166_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 542.0
TLS3_k127_1564166_1 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH K22136 - - 0.000004675 49.0
TLS3_k127_1567819_0 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000003613 217.0
TLS3_k127_1567819_1 Universal stress protein - - - 0.000000000000000000000005495 108.0
TLS3_k127_1567819_2 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000569 94.0
TLS3_k127_1567819_3 Membrane - GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0032505,GO:0043093,GO:0044464,GO:0051301,GO:0071944 - 0.00000000000000001371 91.0
TLS3_k127_1577036_0 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 421.0
TLS3_k127_1577036_1 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000006674 166.0
TLS3_k127_1577036_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000005344 149.0
TLS3_k127_1582464_0 Ankyrin repeat domain-containing protein K21440 GO:0002262,GO:0002376,GO:0002520,GO:0003674,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005783,GO:0005829,GO:0005856,GO:0005886,GO:0005938,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006887,GO:0006888,GO:0006996,GO:0007010,GO:0007163,GO:0007275,GO:0008092,GO:0008093,GO:0008104,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010638,GO:0012505,GO:0014731,GO:0015672,GO:0016020,GO:0016043,GO:0016192,GO:0016323,GO:0016528,GO:0016529,GO:0018130,GO:0019438,GO:0019899,GO:0030011,GO:0030016,GO:0030017,GO:0030018,GO:0030097,GO:0030099,GO:0030154,GO:0030218,GO:0030424,GO:0030507,GO:0030673,GO:0030674,GO:0030863,GO:0031252,GO:0031253,GO:0031256,GO:0031430,GO:0031672,GO:0031674,GO:0032501,GO:0032502,GO:0032589,GO:0032940,GO:0033013,GO:0033014,GO:0033036,GO:0033043,GO:0033267,GO:0034101,GO:0034613,GO:0034641,GO:0035088,GO:0035090,GO:0042383,GO:0042592,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043292,GO:0044237,GO:0044249,GO:0044271,GO:0044304,GO:0044422,GO:0044424,GO:0044425,GO:0044444,GO:0044448,GO:0044449,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045197,GO:0045199,GO:0045202,GO:0045211,GO:0046483,GO:0046903,GO:0046907,GO:0048193,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048534,GO:0048731,GO:0048821,GO:0048856,GO:0048869,GO:0048872,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0051117,GO:0051128,GO:0051130,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0051641,GO:0051649,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0060090,GO:0061245,GO:0061515,GO:0065007,GO:0065008,GO:0070727,GO:0071704,GO:0071840,GO:0071944,GO:0072657,GO:0072659,GO:0097060,GO:0097458,GO:0098590,GO:0098771,GO:0098794,GO:0099080,GO:0099081,GO:0099512,GO:0099568,GO:0120025,GO:0120038,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1990778 - 0.00000005869 64.0
TLS3_k127_1582464_1 Polysaccharide biosynthesis/export protein K01991 - - 0.0001815 51.0
TLS3_k127_159116_0 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 394.0
TLS3_k127_159116_1 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 310.0
TLS3_k127_159116_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 312.0
TLS3_k127_159116_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000009603 244.0
TLS3_k127_159116_4 topology modulation protein - - - 0.00000000000000000000000000000000000000000000000000000000002517 209.0
TLS3_k127_159116_5 YndJ-like protein - - - 0.000000000000000000000000000000000000000352 162.0
TLS3_k127_159116_6 YceI-like domain - - - 0.00000000000000000000000000000000007371 143.0
TLS3_k127_159116_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000001013 105.0
TLS3_k127_159116_8 Involved in formation and maintenance of cell shape K03570 - - 0.000000006751 61.0
TLS3_k127_159116_9 shape-determining protein MreD K03571 - - 0.0000527 53.0
TLS3_k127_1627122_0 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 336.0
TLS3_k127_1627122_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 321.0
TLS3_k127_1627122_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000001047 252.0
TLS3_k127_1627122_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000001164 87.0
TLS3_k127_1634745_0 A-macroglobulin complement component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008539 480.0
TLS3_k127_1634745_1 Protein of unknown function (DUF2891) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002461 250.0
TLS3_k127_1648_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000004547 216.0
TLS3_k127_1648_1 - - - - 0.0000000504 63.0
TLS3_k127_1648_2 Putative zinc-finger - GO:0005575,GO:0016020 - 0.0002437 51.0
TLS3_k127_1664913_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000001608 166.0
TLS3_k127_1664913_1 Penicillinase repressor - - - 0.000000000000000000003041 101.0
TLS3_k127_1664913_2 Zn-dependent protease with chaperone function - - - 0.0001602 52.0
TLS3_k127_1697586_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 510.0
TLS3_k127_1697586_2 von Willebrand factor, type A - - - 0.0000000000000000000000000005984 125.0
TLS3_k127_1697586_3 cell redox homeostasis - - - 0.00000000000004307 80.0
TLS3_k127_1697586_4 Protein conserved in bacteria - - - 0.000001244 59.0
TLS3_k127_1715210_0 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000001608 176.0
TLS3_k127_1715210_1 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000007919 171.0
TLS3_k127_1715210_2 Belongs to the peptidase M10A family K07761,K07999 GO:0001101,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009628,GO:0009651,GO:0009719,GO:0009725,GO:0009753,GO:0010033,GO:0010035,GO:0010038,GO:0016020,GO:0016787,GO:0019538,GO:0031224,GO:0031225,GO:0032502,GO:0040007,GO:0042221,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046686,GO:0048519,GO:0048580,GO:0048583,GO:0048589,GO:0048831,GO:0050789,GO:0050793,GO:0050896,GO:0051093,GO:0051239,GO:0051241,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080186,GO:0140096,GO:1900055,GO:1900056,GO:1901564,GO:1901700,GO:1905622,GO:2000024,GO:2000026,GO:2000028,GO:2000241 - 0.0001207 55.0
TLS3_k127_1720683_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 9.95e-207 655.0
TLS3_k127_1720683_1 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 303.0
TLS3_k127_1720683_2 decarboxylase K00486,K01593 - 1.14.13.9,4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003855 286.0
TLS3_k127_1720683_3 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000002737 99.0
TLS3_k127_172636_0 Voltage-dependent anion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 408.0
TLS3_k127_172636_1 oxidoreductase activity, acting on diphenols and related substances as donors - - - 0.00000000000000000000000000005784 119.0
TLS3_k127_172636_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000008184 103.0
TLS3_k127_1727755_0 Phosphoglucose isomerase K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 557.0
TLS3_k127_1727755_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009614 424.0
TLS3_k127_1727755_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281,K12132 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 0.0000000000000000000000000000000000000000000000000000001643 202.0
TLS3_k127_1727755_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000002505 151.0
TLS3_k127_1732157_0 Sodium:sulfate symporter transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000125 301.0
TLS3_k127_1732157_1 NnrU protein K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000001789 222.0
TLS3_k127_1735791_0 Domain of unknown function (DUF5110) K01187 - 3.2.1.20 5.108e-198 644.0
TLS3_k127_1735791_1 Glucodextranase, domain N K01178 - 3.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 386.0
TLS3_k127_1735791_3 Glucokinase K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000001415 233.0
TLS3_k127_1736996_0 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007041 378.0
TLS3_k127_1736996_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007259 250.0
TLS3_k127_1736996_2 NADPH-dependent FMN reductase K19784 - - 0.000000000000000000000000000000000000000000000002934 174.0
TLS3_k127_1736996_3 Zinc-binding dehydrogenase - - - 0.0000000000000000000007888 96.0
TLS3_k127_1736996_4 Histidine kinase K07678 - 2.7.13.3 0.00000000000000004417 88.0
TLS3_k127_1736996_5 Calcineurin-like phosphoesterase K14379 - 3.1.3.2 0.000000000001875 70.0
TLS3_k127_1736996_6 - - - - 0.00000005669 59.0
TLS3_k127_1737738_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002606 285.0
TLS3_k127_1737738_1 Actin K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001288 258.0
TLS3_k127_1737738_2 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000001076 198.0
TLS3_k127_1737738_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.00000000000000000000000000000000000000000000000003712 188.0
TLS3_k127_1742520_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 440.0
TLS3_k127_1742520_1 Aldehyde dehydrogenase family K22445 - 1.2.99.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 374.0
TLS3_k127_1742520_2 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000534 241.0
TLS3_k127_1742743_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 610.0
TLS3_k127_1742743_1 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 537.0
TLS3_k127_1742743_2 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000009344 178.0
TLS3_k127_1744604_0 Ribonuclease HII K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 379.0
TLS3_k127_1744604_1 PFAM Cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000002917 167.0
TLS3_k127_1744604_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.000000000000000121 84.0
TLS3_k127_1747937_0 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 511.0
TLS3_k127_1756010_0 serine-type exopeptidase activity K01322 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 5.361e-306 955.0
TLS3_k127_1764452_0 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 293.0
TLS3_k127_1764452_1 SPFH Band 7 PHB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008612 251.0
TLS3_k127_1782136_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 477.0
TLS3_k127_1782136_1 CheC inhibitor of MCP methylation K03410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002551 255.0
TLS3_k127_1782136_2 Methyltransferase, chemotaxis proteins K00575,K13486 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000489 199.0
TLS3_k127_1782136_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000005842 161.0
TLS3_k127_1782136_4 Response regulator receiver domain K03413 - - 0.000000000000000000000000000000000194 136.0
TLS3_k127_1782136_5 Response regulator receiver K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000003602 130.0
TLS3_k127_1797336_0 Pyridoxamine 5'-phosphate oxidase like - - - 0.000000000000000000000000000000000000000000000000000000000002309 213.0
TLS3_k127_1797336_1 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.00000000000000000000000000000000000000000000000000000000005673 208.0
TLS3_k127_1797336_2 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000002039 169.0
TLS3_k127_17980_0 Phosphate acyltransferases K00655,K01897 - 2.3.1.51,6.2.1.3 0.00000000000000000000000000000000000000000000000000000000002418 221.0
TLS3_k127_17980_1 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000337 144.0
TLS3_k127_17980_2 Universal stress protein family - - - 0.0000000000000000000001355 104.0
TLS3_k127_1805389_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 318.0
TLS3_k127_1805389_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006398 248.0
TLS3_k127_1805389_2 DNA-templated transcription, initiation K02405 - - 0.000000000000000000000000000000000000000000000000001018 188.0
TLS3_k127_1805389_3 - - - - 0.0000000002271 70.0
TLS3_k127_1810383_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002482 299.0
TLS3_k127_1810383_1 - - - - 0.00007285 51.0
TLS3_k127_1812909_0 Disulphide isomerase - - - 0.0000000000000000000000000000000000000000000000000000003685 196.0
TLS3_k127_1812909_1 - - - - 0.000000000000000000000000000006856 123.0
TLS3_k127_1812909_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000004051 106.0
TLS3_k127_1812909_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000003387 106.0
TLS3_k127_1816362_0 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 457.0
TLS3_k127_1816362_1 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 415.0
TLS3_k127_1816362_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 315.0
TLS3_k127_1816362_3 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000004281 126.0
TLS3_k127_1834055_0 Pilus assembly protein PilX K02673 - - 0.0000000000000001006 94.0
TLS3_k127_1834055_1 AAA ATPase domain - - - 0.000000000007295 71.0
TLS3_k127_1834055_2 Prokaryotic N-terminal methylation motif K02671 - - 0.00008333 51.0
TLS3_k127_1843546_0 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000009552 201.0
TLS3_k127_1843546_1 cell redox homeostasis K22278 - 3.5.1.104 0.00000000000000000000000486 116.0
TLS3_k127_1843546_2 Thioredoxin-like - - - 0.000000000000000000005455 106.0
TLS3_k127_1843546_3 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000003211 79.0
TLS3_k127_1843546_4 Thioredoxin-like - - - 0.0000002962 58.0
TLS3_k127_1849317_0 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 355.0
TLS3_k127_1849317_1 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003251 255.0
TLS3_k127_1849317_2 dUTP metabolic process K01520,K13886,K21286 GO:0000166,GO:0000287,GO:0001889,GO:0003674,GO:0003824,GO:0004170,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0006139,GO:0006163,GO:0006195,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006259,GO:0006260,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010469,GO:0010646,GO:0010648,GO:0014070,GO:0015949,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0023051,GO:0023057,GO:0030545,GO:0030547,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032552,GO:0032556,GO:0034404,GO:0034641,GO:0034645,GO:0034654,GO:0034655,GO:0035862,GO:0035863,GO:0035870,GO:0036094,GO:0042221,GO:0042975,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043393,GO:0043497,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048732,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051259,GO:0051260,GO:0055086,GO:0061008,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0072529,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:0098772,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:2000272 3.5.1.122,3.6.1.23 0.00000000000000000000000000000000000000001439 157.0
TLS3_k127_1849317_3 - - - - 0.0000000000000002306 89.0
TLS3_k127_1850215_0 arylformamidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 301.0
TLS3_k127_1850215_1 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002716 254.0
TLS3_k127_1850215_2 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000005559 216.0
TLS3_k127_1850215_3 ABC transporter permease K02066 - - 0.00000000000000000000005058 102.0
TLS3_k127_1850215_4 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000006559 81.0
TLS3_k127_1851304_0 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 497.0
TLS3_k127_1851304_1 Glucose inhibited division protein A - - - 0.00000000000000002845 93.0
TLS3_k127_1864468_0 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 505.0
TLS3_k127_1864468_1 YjbR - - - 0.00000000000000000000000000000000000000005535 153.0
TLS3_k127_1864468_2 peroxiredoxin activity K03564 - 1.11.1.15 0.000000000000003649 79.0
TLS3_k127_1891419_0 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 470.0
TLS3_k127_1891419_1 Oxidoreductase family, NAD-binding Rossmann fold - GO:0005575,GO:0005576,GO:0008150,GO:0009987,GO:0016043,GO:0030198,GO:0031012,GO:0043062,GO:0044421,GO:0071840 - 0.0002688 48.0
TLS3_k127_1895287_0 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 609.0
TLS3_k127_1895287_1 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000003104 172.0
TLS3_k127_1895287_2 Putative zinc-finger - - - 0.0000000000000000000000000000000000000000107 163.0
TLS3_k127_1895287_3 Glucose / Sorbosone dehydrogenase - - - 0.00000002863 58.0
TLS3_k127_190113_0 COG0635 Coproporphyrinogen III oxidase and related Fe-S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 412.0
TLS3_k127_190113_1 COG0644 Dehydrogenases (flavoproteins) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 293.0
TLS3_k127_1902037_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 1.053e-275 873.0
TLS3_k127_190652_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 499.0
TLS3_k127_190652_1 Domain of unknown function (DUF1972) K12996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004591 407.0
TLS3_k127_190652_2 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005257 275.0
TLS3_k127_190652_3 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000001148 267.0
TLS3_k127_190652_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000002379 155.0
TLS3_k127_190652_5 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000006354 110.0
TLS3_k127_190652_6 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000007793 97.0
TLS3_k127_190652_7 - - - - 0.0000000000000000371 83.0
TLS3_k127_190652_8 KH domain K06960 - - 0.000000000000001003 80.0
TLS3_k127_190652_9 Tetratricopeptide repeat - - - 0.000000000001175 81.0
TLS3_k127_1912144_0 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000457 205.0
TLS3_k127_1912144_1 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000001048 188.0
TLS3_k127_1912191_0 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 615.0
TLS3_k127_1912191_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 404.0
TLS3_k127_1912191_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001201 276.0
TLS3_k127_1912191_3 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000004296 214.0
TLS3_k127_1912191_4 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.000000000000000000004379 101.0
TLS3_k127_1912962_0 - K05826 - - 0.0000000006944 61.0
TLS3_k127_1912962_1 von Willebrand factor, type A K07114 - - 0.000000002859 69.0
TLS3_k127_1912962_2 Major facilitator superfamily - - - 0.00006486 53.0
TLS3_k127_1916725_0 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 486.0
TLS3_k127_1916725_1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000002002 89.0
TLS3_k127_1916725_2 PD-(D/E)XK nuclease superfamily - - - 0.000000001652 72.0
TLS3_k127_1916825_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000002454 177.0
TLS3_k127_1916825_1 Belongs to the peptidase S41A family K06399 - 3.4.21.116 0.0001078 53.0
TLS3_k127_1925727_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 409.0
TLS3_k127_1925727_1 Peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 377.0
TLS3_k127_1927117_0 typically periplasmic contain C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002579 289.0
TLS3_k127_1927117_1 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001868 276.0
TLS3_k127_1931450_0 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 492.0
TLS3_k127_1931450_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 483.0
TLS3_k127_1931450_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 454.0
TLS3_k127_1931450_3 Protein of unknown function (DUF1698) K15257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 351.0
TLS3_k127_1931450_4 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 348.0
TLS3_k127_1931450_5 PFAM Phosphoglycerate mutase - - - 0.00000000000000000000000000000000000000000000001598 178.0
TLS3_k127_1931450_6 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000001185 152.0
TLS3_k127_1931450_7 - - - - 0.000000000000000003196 93.0
TLS3_k127_1963306_0 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000008605 242.0
TLS3_k127_1963306_1 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000001221 238.0
TLS3_k127_1963306_2 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000001916 203.0
TLS3_k127_1968737_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 422.0
TLS3_k127_1974915_0 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.00000000000000000000000000000000003447 142.0
TLS3_k127_1974915_1 PFAM D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0000000000000004151 85.0
TLS3_k127_1974915_2 Tetratricopeptide repeat - - - 0.0000001726 63.0
TLS3_k127_1974915_3 aspartic-type endopeptidase activity - - - 0.0000203 57.0
TLS3_k127_1982126_0 Carboxypeptidase regulatory-like domain - - - 4.679e-265 846.0
TLS3_k127_1982126_1 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000001626 172.0
TLS3_k127_1989823_0 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001591 266.0
TLS3_k127_1989823_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000003388 215.0
TLS3_k127_1989823_2 Hemolysin III K11068 - - 0.0009687 42.0
TLS3_k127_2015839_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000002223 254.0
TLS3_k127_2015839_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000003627 129.0
TLS3_k127_2015839_2 Preprotein translocase subunit K03210 - - 0.00000000000000008817 84.0
TLS3_k127_2017428_0 Male sterility protein K01897 - 6.2.1.3 3.845e-194 625.0
TLS3_k127_2025483_0 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 472.0
TLS3_k127_2025483_1 Domain of unknown function (DUF1990) - - - 0.000000000000000000000000000000000000000004677 158.0
TLS3_k127_2029316_0 RmlD substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 433.0
TLS3_k127_2029316_1 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 366.0
TLS3_k127_2029316_2 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000003781 224.0
TLS3_k127_2029316_3 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000007302 206.0
TLS3_k127_2029316_4 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000003043 115.0
TLS3_k127_2031993_0 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000005062 248.0
TLS3_k127_2031993_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000007599 221.0
TLS3_k127_2031993_3 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00004802 47.0
TLS3_k127_206410_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.288e-194 629.0
TLS3_k127_206410_1 Hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002955 266.0
TLS3_k127_2073177_0 Belongs to the HpcH HpaI aldolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 469.0
TLS3_k127_2073177_1 membrane protein, TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009452 319.0
TLS3_k127_2073177_2 PFAM bifunctional deaminase-reductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 293.0
TLS3_k127_2073177_3 UPF0314 protein - - - 0.0000000000000000000000000000000000000002196 156.0
TLS3_k127_207824_0 mechanosensitive ion channel K05802 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 391.0
TLS3_k127_207824_1 - - - - 0.00005738 49.0
TLS3_k127_210026_0 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000408 258.0
TLS3_k127_2101971_0 Zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 411.0
TLS3_k127_2101971_1 HlyD family secretion protein K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 321.0
TLS3_k127_2101971_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003135 252.0
TLS3_k127_2101971_3 - - - - 0.000000000000000000000000000000000000000000000000000000000001925 216.0
TLS3_k127_2101971_4 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000002133 162.0
TLS3_k127_2101971_5 von Willebrand factor, type A - - - 0.00000000000000000000000002467 121.0
TLS3_k127_2101971_6 ribosomal large subunit export from nucleus - - - 0.000000000000000000000001549 110.0
TLS3_k127_2101971_7 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000001868 76.0
TLS3_k127_2101971_8 Universal stress protein family - - - 0.00002678 52.0
TLS3_k127_210595_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 354.0
TLS3_k127_210595_2 Polymer-forming cytoskeletal - - - 0.00000000000000002769 90.0
TLS3_k127_210595_3 HEAT repeats - - - 0.0008169 49.0
TLS3_k127_2143868_0 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000000000001073 225.0
TLS3_k127_2143868_1 Alpha/beta hydrolase family K07020 - - 0.00000000000000000000000000000000000000000006488 168.0
TLS3_k127_2143868_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000119 114.0
TLS3_k127_2143868_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00004235 54.0
TLS3_k127_2188145_0 TIGRFAM MazG family protein K02428,K04765 - 3.6.1.66,3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000628 260.0
TLS3_k127_2188145_1 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.0000000000000000000000000000000001233 138.0
TLS3_k127_2188145_2 Domain of unknown function (DUF1844) - - - 0.0000000000003229 77.0
TLS3_k127_2221486_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 292.0
TLS3_k127_2221486_1 AcrB/AcrD/AcrF family - - - 0.0000000000000000000000000000000000000000000000000000000000000004844 223.0
TLS3_k127_223005_0 transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 467.0
TLS3_k127_223005_1 chorismate binding enzyme K01665,K03342 - 2.6.1.85,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 393.0
TLS3_k127_2247494_0 Belongs to the aldehyde dehydrogenase family K00141,K22187 - 1.2.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 616.0
TLS3_k127_2247494_1 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 466.0
TLS3_k127_2247494_2 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 316.0
TLS3_k127_2247494_3 Bacteriocin-protection protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001281 230.0
TLS3_k127_2247494_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000001668 192.0
TLS3_k127_2247494_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000002669 65.0
TLS3_k127_2250030_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008408 533.0
TLS3_k127_2250030_1 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000005197 179.0
TLS3_k127_2250137_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 513.0
TLS3_k127_2292404_0 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 1.353e-222 696.0
TLS3_k127_2292404_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000005931 180.0
TLS3_k127_2292404_2 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000004474 128.0
TLS3_k127_2292404_3 phosphorelay signal transduction system - - - 0.00001817 49.0
TLS3_k127_2319756_0 ThiS family K21029,K21147 - 2.7.7.80,2.8.1.11 2.585e-197 625.0
TLS3_k127_2319756_1 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 403.0
TLS3_k127_2319756_2 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 370.0
TLS3_k127_2319756_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002135 266.0
TLS3_k127_2319756_4 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009836 260.0
TLS3_k127_2319756_5 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000001609 183.0
TLS3_k127_2335404_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 353.0
TLS3_k127_2335404_1 endonuclease exonuclease phosphatase K07004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 313.0
TLS3_k127_233844_0 Peptidase M1, membrane alanine aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 358.0
TLS3_k127_233844_1 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 310.0
TLS3_k127_233844_2 PFAM Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 313.0
TLS3_k127_233844_3 Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001672 295.0
TLS3_k127_233844_4 Tetratricopeptide repeat - - - 0.000002141 61.0
TLS3_k127_234679_0 Flavin-binding monooxygenase-like - - - 2.105e-229 719.0
TLS3_k127_234679_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 381.0
TLS3_k127_234679_2 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.0000000000000000000000000000000000008198 147.0
TLS3_k127_234679_3 CoA binding domain K06929 - - 0.000000000000000000000000000007648 121.0
TLS3_k127_2370559_0 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 525.0
TLS3_k127_2370559_1 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000004067 141.0
TLS3_k127_2370736_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 448.0
TLS3_k127_2394235_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 496.0
TLS3_k127_2394235_1 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 336.0
TLS3_k127_2394235_2 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004908 283.0
TLS3_k127_2394235_3 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000006872 229.0
TLS3_k127_2394235_4 - - - - 0.000000003856 66.0
TLS3_k127_2450060_0 Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 306.0
TLS3_k127_2450060_1 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000000000000000000000002993 191.0
TLS3_k127_246531_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 294.0
TLS3_k127_246531_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000003527 177.0
TLS3_k127_246531_2 Preprotein translocase SecG subunit K03075 - - 0.0000004135 56.0
TLS3_k127_2479664_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005501 258.0
TLS3_k127_2479664_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002725 261.0
TLS3_k127_2479664_2 Mut7-C RNAse domain - - - 0.0000000000000000000000000000001245 127.0
TLS3_k127_2479664_3 - - - - 0.0000000000000000000000000000002579 129.0
TLS3_k127_2479664_4 Protein of unknown function (DUF433) - - - 0.0000000000000000000000000614 109.0
TLS3_k127_250528_0 Tricorn protease C1 domain K03797 - 3.4.21.102 0.000000000000000000000000000000000003538 154.0
TLS3_k127_250528_1 SMART metal-dependent phosphohydrolase, HD K06885 - - 0.000000000000000000000000000004923 127.0
TLS3_k127_250528_2 MgtE intracellular N domain - - - 0.0000000000000001436 80.0
TLS3_k127_250528_3 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0004807 51.0
TLS3_k127_2515321_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000004248 235.0
TLS3_k127_2515321_1 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000006727 199.0
TLS3_k127_2515321_2 D-alanyl-d-alanine carboxypeptidase K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000001032 170.0
TLS3_k127_2515321_3 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000001109 114.0
TLS3_k127_2515321_4 DinB family - - - 0.00000000007262 69.0
TLS3_k127_253631_0 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000002528 243.0
TLS3_k127_253631_1 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000007364 112.0
TLS3_k127_253631_2 Tetratricopeptide TPR_2 repeat protein - - - 0.00000008892 64.0
TLS3_k127_253631_3 - - - - 0.0000004772 62.0
TLS3_k127_253631_4 Domain of unknown function (DUF4388) - - - 0.0000009195 60.0
TLS3_k127_253631_5 COG3209 Rhs family protein - - - 0.0000431 55.0
TLS3_k127_2545489_0 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000001263 208.0
TLS3_k127_2545489_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000003858 156.0
TLS3_k127_2545489_2 - - - - 0.0000000000000000000000000414 113.0
TLS3_k127_255126_0 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000003787 147.0
TLS3_k127_255126_1 Type II secretion system (T2SS), protein G K02456 - - 0.00003601 55.0
TLS3_k127_2594995_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.181e-289 905.0
TLS3_k127_2594995_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000006419 229.0
TLS3_k127_2594995_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000001309 227.0
TLS3_k127_2594995_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000002259 86.0
TLS3_k127_2600029_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 400.0
TLS3_k127_2600029_1 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 327.0
TLS3_k127_2600029_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000005298 192.0
TLS3_k127_2603265_0 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 362.0
TLS3_k127_2603265_1 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009826 294.0
TLS3_k127_2603265_2 SEC-C domain protein K09858 - - 0.000000000000000000000000000000000000000000002007 169.0
TLS3_k127_2607109_0 PFAM Type II secretion system protein E K02652 - - 1.623e-216 687.0
TLS3_k127_2607109_1 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000000000000000000000000000000000000002616 201.0
TLS3_k127_2607109_2 Belongs to the GSP D family K02453 - - 0.000000000000009763 85.0
TLS3_k127_2610204_0 efflux transmembrane transporter activity K02004 - - 1.459e-198 644.0
TLS3_k127_2610204_1 Glycoside hydrolase family 16 K01216 - 3.2.1.73 0.0000000000000000000000009534 104.0
TLS3_k127_2611802_0 Protein of unknown function (DUF819) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 512.0
TLS3_k127_2611802_1 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 445.0
TLS3_k127_2611802_2 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000001747 201.0
TLS3_k127_2611802_3 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.000000000000000000000000000000000003266 145.0
TLS3_k127_2613870_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 2.688e-249 778.0
TLS3_k127_2613870_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 282.0
TLS3_k127_2613870_2 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000032 269.0
TLS3_k127_2613870_3 Psort location Cytoplasmic, score K07586 - - 0.0000000000000000685 86.0
TLS3_k127_2613874_0 UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 471.0
TLS3_k127_2614002_0 Glutamine cyclotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005455 278.0
TLS3_k127_2614002_1 Domain of unknown function (DUF3488) - - - 0.000000000000000000000000000000000000000000000000005219 199.0
TLS3_k127_2618219_0 Homoserine dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007509 280.0
TLS3_k127_2618219_1 Xylose isomerase-like TIM barrel K06606 - 5.3.99.11 0.00000000000000000000000000000000000000000000000000000000000007338 222.0
TLS3_k127_2618219_2 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000001244 191.0
TLS3_k127_2618811_0 asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 439.0
TLS3_k127_2618811_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 372.0
TLS3_k127_2618811_2 Belongs to the ATCase OTCase family K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 341.0
TLS3_k127_2618811_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002374 287.0
TLS3_k127_2618811_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000001022 260.0
TLS3_k127_2618811_5 Pfam Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000001298 215.0
TLS3_k127_2618811_6 - - - - 0.00000000000000000000000000001904 125.0
TLS3_k127_2618811_7 Helix-hairpin-helix DNA-binding, class 1 K02347 - - 0.0000000000000000000000000001443 120.0
TLS3_k127_2626287_0 Phage tail sheath protein K06907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 436.0
TLS3_k127_2626287_1 Protein of unknown function (DUF4255) - - - 0.00000000000000000000000000000000000000000000000000000005377 205.0
TLS3_k127_2634255_0 Adenylate cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001287 263.0
TLS3_k127_2634255_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006009 243.0
TLS3_k127_2634255_2 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000008458 227.0
TLS3_k127_2634255_3 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000000000001362 151.0
TLS3_k127_2634255_4 cAMP biosynthetic process K03641 - - 0.000000000000000000001488 95.0
TLS3_k127_2634255_5 Thioredoxin-like - - - 0.00000000000000000001867 106.0
TLS3_k127_2637913_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 8.946e-206 651.0
TLS3_k127_2637913_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000001865 236.0
TLS3_k127_2639039_0 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 357.0
TLS3_k127_2639039_1 Peptidase dimerization domain protein - - - 0.0000000000000000000000000000000000000000000000000000000007404 205.0
TLS3_k127_2639039_2 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000001862 200.0
TLS3_k127_2647240_0 Carboxymethylenebutenolidase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000096 454.0
TLS3_k127_2647240_1 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 302.0
TLS3_k127_2647240_2 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000244 247.0
TLS3_k127_2647240_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000007552 95.0
TLS3_k127_2649119_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 352.0
TLS3_k127_2659957_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 329.0
TLS3_k127_2659957_1 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 312.0
TLS3_k127_2659957_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000000001983 156.0
TLS3_k127_2659957_3 peptidyl-prolyl isomerase K01802,K03769 - 5.2.1.8 0.000000000000004467 85.0
TLS3_k127_2671510_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 467.0
TLS3_k127_2671510_1 cAMP biosynthetic process K00870,K12132 - 2.7.1.37,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 437.0
TLS3_k127_2671510_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002871 290.0
TLS3_k127_2671510_3 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000000003864 227.0
TLS3_k127_2671510_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000006729 160.0
TLS3_k127_2671510_5 COG1012 NAD-dependent aldehyde - - - 0.0009687 42.0
TLS3_k127_2682947_0 PNKP adenylyltransferase domain, ligase domain - - - 0.0 1162.0
TLS3_k127_2682947_1 RNA repair, ligase-Pnkp-associating, region of Hen1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 406.0
TLS3_k127_2711201_0 Chlorite dismutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004488 282.0
TLS3_k127_2711201_1 - - - - 0.000002775 60.0
TLS3_k127_2716890_0 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 337.0
TLS3_k127_2716890_1 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008716 304.0
TLS3_k127_2716890_2 Protein of unknown function (DUF3311) - - - 0.00000000000007158 74.0
TLS3_k127_2720744_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000764 417.0
TLS3_k127_2720744_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000001076 233.0
TLS3_k127_2720744_2 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000325 132.0
TLS3_k127_2720744_3 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000007793 105.0
TLS3_k127_2720744_4 multi-organism process K03195 - - 0.0000000000000003535 90.0
TLS3_k127_27236_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000006464 205.0
TLS3_k127_27236_1 maltose O-acetyltransferase activity - - - 0.00000000000000000000000000000000000000000000000001144 189.0
TLS3_k127_27236_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000009258 125.0
TLS3_k127_2730335_0 oxidoreductase activity, acting on CH-OH group of donors K13237 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 297.0
TLS3_k127_2730335_1 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000001948 243.0
TLS3_k127_2730335_2 Inositol monophosphatase family K01092,K05602 - 3.1.3.15,3.1.3.25 0.0000000000000000000000000000000000000000000004928 169.0
TLS3_k127_2730335_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000002462 177.0
TLS3_k127_2738948_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002464 287.0
TLS3_k127_2738948_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000003937 172.0
TLS3_k127_2738948_2 PFAM von Willebrand factor type A - - - 0.000000000000000007267 89.0
TLS3_k127_2759889_0 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 370.0
TLS3_k127_2759889_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000003926 264.0
TLS3_k127_2759889_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000009581 169.0
TLS3_k127_2759889_3 outer membrane autotransporter barrel domain protein - - - 0.00000000000000000000002816 105.0
TLS3_k127_2761238_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009534 476.0
TLS3_k127_2761238_1 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 429.0
TLS3_k127_2761238_2 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009906 264.0
TLS3_k127_2761238_3 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000006889 119.0
TLS3_k127_2761238_4 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.000000000000000000000000000008234 129.0
TLS3_k127_2761303_0 UPF0210 protein K09157 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 426.0
TLS3_k127_2761303_1 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000329 234.0
TLS3_k127_2761303_2 Low affinity iron permease - - - 0.00000000000000000000000000000000000000000000000007595 183.0
TLS3_k127_2761303_3 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000008623 182.0
TLS3_k127_2761303_4 Carbon dioxide concentrating mechanism carboxysome shell protein - - - 0.000000000000000000000000000002824 123.0
TLS3_k127_2765397_0 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000334 149.0
TLS3_k127_2765397_1 Tetratricopeptide repeat - - - 0.0005556 51.0
TLS3_k127_2770193_0 choline dehydrogenase activity - - - 7.652e-258 802.0
TLS3_k127_2770193_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 462.0
TLS3_k127_2770193_2 lipopolysaccharide transport K22110 - - 0.0000000000000000000764 93.0
TLS3_k127_2779417_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 617.0
TLS3_k127_2779417_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 498.0
TLS3_k127_2779417_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 516.0
TLS3_k127_2779417_3 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 331.0
TLS3_k127_2779417_4 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000001031 257.0
TLS3_k127_2780329_0 Male sterility protein K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 603.0
TLS3_k127_2780329_1 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 532.0
TLS3_k127_2793538_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.000000000000000000000000000000001882 134.0
TLS3_k127_2793538_1 Fatty acid desaturase K00508 - 1.14.19.3 0.000000000000000000000000005962 110.0
TLS3_k127_2793538_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.000000000000000009698 90.0
TLS3_k127_2801128_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 4.939e-309 963.0
TLS3_k127_2801128_1 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 315.0
TLS3_k127_2801128_2 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001386 250.0
TLS3_k127_2801128_3 AI-2E family transporter - - - 0.000000000000000000000000000000001014 145.0
TLS3_k127_2803682_0 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 413.0
TLS3_k127_2803682_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000004271 270.0
TLS3_k127_2803682_2 PspA/IM30 family K03969 - - 0.000000000000000000000000000000000000001363 156.0
TLS3_k127_2803682_3 - - - - 0.000000000000137 81.0
TLS3_k127_2811328_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000003656 208.0
TLS3_k127_2811328_1 NIPSNAP - - - 0.0000000000000000000000007082 108.0
TLS3_k127_2811328_3 ATPase kinase involved in NAD metabolism - - - 0.000000001919 63.0
TLS3_k127_281654_0 Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate K00294 - 1.2.1.88 1.016e-213 676.0
TLS3_k127_281654_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001162 276.0
TLS3_k127_281770_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000001346 182.0
TLS3_k127_281770_1 BMC - - - 0.00000000000000000000000000000000000007849 146.0
TLS3_k127_281770_2 PFAM Aldehyde dehydrogenase - - - 0.00000000000000000005235 92.0
TLS3_k127_281770_3 Helix-turn-helix domain K15539 - - 0.000000000001142 75.0
TLS3_k127_2820_0 NADH oxidase - - - 2.252e-203 644.0
TLS3_k127_2820_1 Aminotransferase class-V K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 473.0
TLS3_k127_2820_2 NADH flavin oxidoreductase NADH oxidase K09461 - 1.14.13.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 371.0
TLS3_k127_2820_3 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000008406 108.0
TLS3_k127_2827155_0 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007629 366.0
TLS3_k127_2827155_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000001855 222.0
TLS3_k127_28366_0 PFAM amidohydrolase - - - 7.233e-290 903.0
TLS3_k127_28366_1 PFAM Leukotriene A4 hydrolase, C-terminal - - - 1.095e-213 681.0
TLS3_k127_28366_2 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 352.0
TLS3_k127_2837076_0 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006577 257.0
TLS3_k127_2842435_0 Common central domain of tyrosinase - - - 4.269e-292 923.0
TLS3_k127_287403_0 Phosphoenolpyruvate carboxykinase K01610 - 4.1.1.49 1.135e-212 673.0
TLS3_k127_287403_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008418 492.0
TLS3_k127_287403_2 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.000000000000000000000000000000000000008309 147.0
TLS3_k127_287403_3 - - - - 0.000000000000000001491 88.0
TLS3_k127_2881629_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 327.0
TLS3_k127_2881629_1 TPR repeat - - - 0.0000000000000000000000000000000000000000000002007 182.0
TLS3_k127_2881629_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000008905 76.0
TLS3_k127_2885418_0 Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000001128 228.0
TLS3_k127_2885418_1 BON domain - - - 0.000000000000000000000000004053 126.0
TLS3_k127_2885418_2 PFAM UspA domain protein - - - 0.0001233 46.0
TLS3_k127_2888531_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.054e-289 906.0
TLS3_k127_2888531_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000001875 224.0
TLS3_k127_2888531_2 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000003611 76.0
TLS3_k127_2890122_0 hydrolase, family 3 K05349 - 3.2.1.21 3.459e-258 818.0
TLS3_k127_2890122_1 AMP-binding enzyme K00666,K12426,K12427,K12428,K21059 - 2.7.7.95,6.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 621.0
TLS3_k127_2890122_2 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009199 451.0
TLS3_k127_289169_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 448.0
TLS3_k127_289169_1 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000008461 99.0
TLS3_k127_289169_2 Transglutaminase-like superfamily K22452 - 2.3.2.13 0.0001259 47.0
TLS3_k127_2912868_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009 505.0
TLS3_k127_2912868_1 Winged helix DNA-binding domain K09927 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 410.0
TLS3_k127_2912868_2 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 330.0
TLS3_k127_2923287_1 Belongs to the N(4) N(6)-methyltransferase family K07316 - 2.1.1.72 0.000000000000000000000000000000002053 132.0
TLS3_k127_2923287_2 - - - - 0.0000000000001171 78.0
TLS3_k127_2923287_3 similarity to EGAD 6135 - - - 0.00004346 49.0
TLS3_k127_2927086_0 ATPase associated with various cellular activities, AAA_5 K02584 - - 5.339e-203 649.0
TLS3_k127_2927086_1 Dehydrogenase - - - 0.000000000000000000000000000000004575 145.0
TLS3_k127_2927086_2 OsmC-like protein - - - 0.0000000000000000000002384 100.0
TLS3_k127_2932972_0 4Fe-4S dicluster domain K00184 - - 1.04e-214 694.0
TLS3_k127_293755_0 HELICc2 K03722 - 3.6.4.12 1.313e-201 647.0
TLS3_k127_293755_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 484.0
TLS3_k127_293755_2 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000003873 134.0
TLS3_k127_293755_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000002062 101.0
TLS3_k127_293755_4 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.000000006154 58.0
TLS3_k127_2942080_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 584.0
TLS3_k127_2942080_1 NifU-like N terminal domain K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - 0.000000000000000000000000000000000000000000000000000001969 194.0
TLS3_k127_2942080_2 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000004137 109.0
TLS3_k127_2943840_0 Wzt C-terminal domain K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 402.0
TLS3_k127_2943840_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 290.0
TLS3_k127_2943840_2 3-demethylubiquinone-9 3-O-methyltransferase activity K18827 - 2.1.1.294,2.7.1.181 0.000000000000000000000000000000000051 148.0
TLS3_k127_300142_0 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 586.0
TLS3_k127_300142_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 471.0
TLS3_k127_300142_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 420.0
TLS3_k127_300142_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003197 252.0
TLS3_k127_300142_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000001752 173.0
TLS3_k127_300142_5 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000003569 153.0
TLS3_k127_300142_6 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000001106 134.0
TLS3_k127_300142_7 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000008621 136.0
TLS3_k127_300142_8 Ribosomal protein L17 K02879 - - 0.00000000000000000000000001158 116.0
TLS3_k127_300142_9 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000001331 99.0
TLS3_k127_302952_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 396.0
TLS3_k127_3036048_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 402.0
TLS3_k127_3036048_1 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003854 249.0
TLS3_k127_3037994_0 TIGRFAM acetaldehyde dehydrogenase (acetylating) K00132 - 1.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004557 281.0
TLS3_k127_3037994_1 UPF0210 protein K09157 - - 0.00000000000000000000000000000000000000000000000000008927 191.0
TLS3_k127_3037994_2 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.00000000000000000000000006021 111.0
TLS3_k127_3037994_3 Belongs to the UPF0237 family K07166 - - 0.00000000000000001294 92.0
TLS3_k127_3047357_0 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000003039 133.0
TLS3_k127_3047357_1 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA - - - 0.0000000000000000000001998 107.0
TLS3_k127_3047357_2 coenzyme F390 K01912 - 6.2.1.30 0.0000002827 57.0
TLS3_k127_3059803_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 366.0
TLS3_k127_3059803_1 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000006582 108.0
TLS3_k127_3060180_0 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 299.0
TLS3_k127_3060180_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000006111 145.0
TLS3_k127_3060180_2 ABC transporter, ATP-binding protein K02003 - - 0.0004604 43.0
TLS3_k127_3090320_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.853e-231 724.0
TLS3_k127_3090320_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000001444 249.0
TLS3_k127_3090320_2 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000006083 125.0
TLS3_k127_3090320_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000001415 119.0
TLS3_k127_3090691_0 Carboxypeptidase regulatory-like domain - - - 5.797e-252 814.0
TLS3_k127_3090691_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 563.0
TLS3_k127_3090691_2 Sigma-70 region 2 - - - 0.000000000000000007488 98.0
TLS3_k127_3141731_0 Glycosyl hydrolase family 3 N-terminal domain protein K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000009146 179.0
TLS3_k127_3141731_1 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000006968 115.0
TLS3_k127_317834_0 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 291.0
TLS3_k127_317834_1 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000007517 193.0
TLS3_k127_317834_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000178 188.0
TLS3_k127_317834_3 SnoaL-like polyketide cyclase - - - 0.000000000000000000000009275 103.0
TLS3_k127_3191232_0 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005603 274.0
TLS3_k127_3191232_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000006424 239.0
TLS3_k127_3191232_2 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.0000000000000000000000000000000000000000000000000000005501 202.0
TLS3_k127_3204218_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 578.0
TLS3_k127_3204218_1 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008437 467.0
TLS3_k127_3204218_2 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000247 235.0
TLS3_k127_3204218_3 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000001866 212.0
TLS3_k127_3204218_4 PFAM Major Facilitator Superfamily - - - 0.00000000007797 67.0
TLS3_k127_3223956_0 HD domain K07023 - - 0.00000000000000000000000000000000000006495 149.0
TLS3_k127_3223956_1 - - - - 0.000000000000000000000000000004133 124.0
TLS3_k127_3223956_2 ABC transporter K02003 - - 0.0000000002863 62.0
TLS3_k127_3223956_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0006616 52.0
TLS3_k127_3235496_0 Transposase domain (DUF772) K07487 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 485.0
TLS3_k127_3235496_1 Nacht domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 391.0
TLS3_k127_3235496_2 Nacht domain - - - 0.0000000000008206 70.0
TLS3_k127_3235496_3 Nacht domain - - - 0.0000000001218 66.0
TLS3_k127_3238797_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 311.0
TLS3_k127_3238797_1 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000001746 98.0
TLS3_k127_3238797_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0004391 44.0
TLS3_k127_3266423_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 1.203e-258 810.0
TLS3_k127_3266423_1 Beta-eliminating lyase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 420.0
TLS3_k127_3266423_2 protein tyrosine kinase activity K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 368.0
TLS3_k127_3266423_3 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.00000000000000000000000000005343 123.0
TLS3_k127_3266423_4 Iron-sulphur cluster biosynthesis - - - 0.0000000000409 65.0
TLS3_k127_3280426_0 thiol-disulfide - - - 0.000000000000000000000000000000000000000000002676 169.0
TLS3_k127_3280426_1 Domain of unknown function (DUF4112) - - - 0.00000000000000000000000000319 117.0
TLS3_k127_3280426_2 Peptidase family M1 domain - - - 0.0000000000008086 75.0
TLS3_k127_3293021_0 DEAD/H associated K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 618.0
TLS3_k127_3321303_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0 1071.0
TLS3_k127_3321303_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 432.0
TLS3_k127_3321303_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001435 236.0
TLS3_k127_3321303_3 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000001373 216.0
TLS3_k127_3321303_4 PHP domain protein - - - 0.0000000000000000000000000000000000155 150.0
TLS3_k127_3321303_5 Stress responsive A/B Barrel Domain - - - 0.000000000000002774 79.0
TLS3_k127_3390273_0 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000003113 85.0
TLS3_k127_3390273_1 nucleic acid-binding protein K07066 - - 0.000000000000003859 79.0
TLS3_k127_3390273_2 Domain of unknown function (DUF4263) - - - 0.00000000002553 72.0
TLS3_k127_3390273_4 PBS lyase HEAT-like repeat - - - 0.0001086 45.0
TLS3_k127_3390273_5 Uncharacterised protein family (UPF0175) - - - 0.0005155 46.0
TLS3_k127_3390273_6 - - - - 0.0006373 44.0
TLS3_k127_3416192_0 phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 393.0
TLS3_k127_3416192_1 very-long-chain-acyl-CoA dehydrogenase activity K17880,K18817 - 2.7.1.119,2.7.1.163 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002489 284.0
TLS3_k127_3416192_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000277 238.0
TLS3_k127_3416192_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000007444 175.0
TLS3_k127_3416192_4 protein serine/threonine phosphatase activity - - - 0.00000000000000000000000001909 118.0
TLS3_k127_3416192_5 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000001051 67.0
TLS3_k127_3416192_6 PFAM YcfA-like protein - - - 0.0000001454 56.0
TLS3_k127_3423789_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 460.0
TLS3_k127_3423789_1 RDD family - - - 0.00000000000000000000000000000000000000007371 163.0
TLS3_k127_3423789_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000003726 109.0
TLS3_k127_3441263_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 340.0
TLS3_k127_3441263_1 PFAM Mur ligase K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 297.0
TLS3_k127_3441263_2 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000003489 188.0
TLS3_k127_3441263_3 nudix family K01515 - 3.6.1.13 0.000000000000000000000000000000000000001005 155.0
TLS3_k127_3441263_4 COG1233 Phytoene dehydrogenase and related proteins - - - 0.00000000000001673 82.0
TLS3_k127_3441263_5 metal-dependent membrane protease K07052 - - 0.0000001774 62.0
TLS3_k127_3441263_6 PFAM FAD dependent oxidoreductase K09835 - 5.2.1.13 0.000003616 57.0
TLS3_k127_3444066_0 Putative glucoamylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 589.0
TLS3_k127_3444066_1 Beta-xylosidase K01198 - 3.2.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 578.0
TLS3_k127_3444066_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 374.0
TLS3_k127_3444066_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000003296 127.0
TLS3_k127_3444066_4 Belongs to the peptidase S51 family K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.00000000001892 65.0
TLS3_k127_3457535_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 459.0
TLS3_k127_3457535_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 369.0
TLS3_k127_3457535_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000051 278.0
TLS3_k127_3457535_3 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000004609 201.0
TLS3_k127_3458463_0 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000093 571.0
TLS3_k127_3458463_1 protein conserved in bacteria K04750 - - 0.000000000000000000000000000000000000000000000000000001256 204.0
TLS3_k127_3458463_2 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000001462 188.0
TLS3_k127_3458463_3 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000347 179.0
TLS3_k127_3458463_4 phosphoserine phosphatase activity K07315,K16928 - 3.1.3.3 0.000000000000000000000000000000000000000000002863 170.0
TLS3_k127_3468157_0 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 376.0
TLS3_k127_3468157_1 PFAM short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001823 250.0
TLS3_k127_3468157_10 Protein of unknown function (DUF721) - - - 0.00001778 53.0
TLS3_k127_3468157_2 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000003716 234.0
TLS3_k127_3468157_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000143 214.0
TLS3_k127_3468157_4 septum formation protein Maf K06287 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - 0.000000000000000000000000000000000000000000000000000073 193.0
TLS3_k127_3468157_5 phosphatase - - - 0.0000000000000000000000000000000000000000001279 164.0
TLS3_k127_3468157_6 Bacterial regulatory proteins, tetR family K09017 - - 0.000000000000000000000000000000000001424 146.0
TLS3_k127_3468157_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000034 73.0
TLS3_k127_3468157_8 self proteolysis - - - 0.000000000006383 68.0
TLS3_k127_3468157_9 Phenylacetate-CoA oxygenase K15512 - 1.14.13.208 0.00000000004236 63.0
TLS3_k127_3472095_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 2.627e-313 980.0
TLS3_k127_3472095_1 PFAM Tetratricopeptide TPR_4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 583.0
TLS3_k127_3472095_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 469.0
TLS3_k127_3472095_3 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000001489 153.0
TLS3_k127_3472095_4 methyltransferase activity K21310 - 2.1.1.334 0.00000000000000000000000001655 111.0
TLS3_k127_3472095_5 - - - - 0.0000000000000000000000001105 118.0
TLS3_k127_3479470_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.215e-202 639.0
TLS3_k127_3479470_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000003024 246.0
TLS3_k127_3479470_2 PFAM Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000005419 181.0
TLS3_k127_3479470_3 PFAM Fibronectin, type III domain K01179,K06882 - 3.2.1.4 0.0000000000007043 80.0
TLS3_k127_3505665_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 574.0
TLS3_k127_3505665_1 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 308.0
TLS3_k127_3510962_0 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 356.0
TLS3_k127_3510962_1 - - - - 0.00000000000000000000000000000000000000105 149.0
TLS3_k127_3510962_2 hydroperoxide reductase activity K01607 - 4.1.1.44 0.00000000000000000000000000000000004078 135.0
TLS3_k127_3510962_3 oxidoreductase activity K07114 - - 0.0000000000001277 82.0
TLS3_k127_3522018_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - - 3.782e-291 930.0
TLS3_k127_3522018_1 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000004335 172.0
TLS3_k127_3522018_2 Fibrobacter succinogenes major domain (Fib_succ_major) - - - 0.0000000000000001708 87.0
TLS3_k127_3525657_0 iron-sulfur cluster assembly - - - 0.000000000000000000000000000000000000000000000000000000009084 204.0
TLS3_k127_3525657_1 PFAM GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000004826 184.0
TLS3_k127_3525657_2 glycosyl transferase group 1 K00754 - - 0.00000000000008145 72.0
TLS3_k127_3525657_3 Metallo-beta-lactamase superfamily - - - 0.0001496 44.0
TLS3_k127_3534845_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 337.0
TLS3_k127_3534845_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000001374 184.0
TLS3_k127_3542718_0 Belongs to the GSP D family K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001455 294.0
TLS3_k127_3542718_1 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.00000000000000000000000000000000000000000000000000001105 200.0
TLS3_k127_3542718_2 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000004235 76.0
TLS3_k127_3553011_0 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000000001099 158.0
TLS3_k127_3553011_1 Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000004739 123.0
TLS3_k127_3553011_2 - - - - 0.00000000000000000000003997 109.0
TLS3_k127_3553011_3 COG0500 SAM-dependent methyltransferases K03183 - 2.1.1.163,2.1.1.201 0.0000000000104 74.0
TLS3_k127_3578198_0 Belongs to the glycosyl hydrolase 13 family K21575 - 3.2.1.135 9.983e-280 876.0
TLS3_k127_3578198_1 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000002266 199.0
TLS3_k127_3584006_0 TIGRFAM magnesium chelatase, H subunit K03403 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 540.0
TLS3_k127_3584006_1 PFAM CobN Magnesium Chelatase K02230,K03403 - 6.6.1.1,6.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008888 399.0
TLS3_k127_3584006_2 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000003554 168.0
TLS3_k127_3584006_3 cell redox homeostasis K03671 - - 0.000000000000003016 79.0
TLS3_k127_3589074_0 COG0226 ABC-type phosphate transport system periplasmic K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 449.0
TLS3_k127_3589074_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 344.0
TLS3_k127_3589074_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000238 259.0
TLS3_k127_3589074_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000002476 67.0
TLS3_k127_3589185_0 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 354.0
TLS3_k127_3589185_1 TOBE domain K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 306.0
TLS3_k127_3589185_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000008495 96.0
TLS3_k127_3596489_0 alpha-L-arabinofuranosidase K01209 - 3.2.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 592.0
TLS3_k127_3596489_1 Cellulase (glycosyl hydrolase family 5) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 512.0
TLS3_k127_3596489_2 Tetratricopeptide repeat - - - 0.000001527 59.0
TLS3_k127_3598152_0 Polysaccharide biosynthesis protein K17947 - 5.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008493 430.0
TLS3_k127_3598152_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 292.0
TLS3_k127_3598152_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000004833 181.0
TLS3_k127_3604387_0 Fumarate reductase flavoprotein C-term K00239 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.5.1,1.3.5.4 1.331e-272 851.0
TLS3_k127_3604387_1 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000005773 222.0
TLS3_k127_3604387_2 succinate dehydrogenase K00241 - - 0.0000000000000000007769 90.0
TLS3_k127_3606636_0 - - - - 0.00000001836 67.0
TLS3_k127_3606636_1 Universal stress protein family - - - 0.00000003677 55.0
TLS3_k127_360958_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003059 244.0
TLS3_k127_360958_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000005603 185.0
TLS3_k127_3615410_0 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 404.0
TLS3_k127_3615410_1 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 342.0
TLS3_k127_3615410_2 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000007131 221.0
TLS3_k127_3615410_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000006551 184.0
TLS3_k127_3632303_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 371.0
TLS3_k127_3632303_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01707 - 4.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 311.0
TLS3_k127_3632303_2 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003951 276.0
TLS3_k127_3632303_3 LUD domain K18929 - - 0.000000000000000000000000000000000000000000001163 170.0
TLS3_k127_3661651_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.014e-300 952.0
TLS3_k127_3661651_1 peptidyl-prolyl cis-trans isomerase activity K03769,K03771 - 5.2.1.8 0.000000000000002385 83.0
TLS3_k127_3664481_0 ATP dependent DNA ligase C terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 574.0
TLS3_k127_3664481_1 peptidyl-tyrosine sulfation K03217,K06872 - - 0.00000000000000000000000000000000000481 150.0
TLS3_k127_3664481_2 dna ligase - - - 0.000000000000000000000000000000003794 129.0
TLS3_k127_3664481_3 Plasmid stabilization system - - - 0.00000000000000000000000000000003042 127.0
TLS3_k127_3664481_5 InterPro IPR007367 - - - 0.000000146 55.0
TLS3_k127_3664481_6 DNA-binding helix-turn-helix protein - - - 0.0004646 47.0
TLS3_k127_3665330_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 564.0
TLS3_k127_3665330_1 - - - - 0.0000000000000000000000000001511 128.0
TLS3_k127_3678471_0 AMP-binding enzyme C-terminal domain - - - 6.209e-208 679.0
TLS3_k127_3682455_0 Putative glucoamylase K13688 - - 0.0 1769.0
TLS3_k127_3682455_1 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 475.0
TLS3_k127_3682455_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000003487 175.0
TLS3_k127_3682455_3 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000001498 153.0
TLS3_k127_3691446_0 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 386.0
TLS3_k127_3691446_1 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000001056 231.0
TLS3_k127_3691446_2 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000001558 145.0
TLS3_k127_37037_0 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 616.0
TLS3_k127_37037_1 Circadian clock protein KaiC K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 441.0
TLS3_k127_37037_2 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 449.0
TLS3_k127_37037_3 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 288.0
TLS3_k127_3712397_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 3.166e-310 979.0
TLS3_k127_3712397_1 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 338.0
TLS3_k127_3712397_2 Signal peptidase (SPase) II K03101 - 3.4.23.36 0.0000000000000000000000000000000003521 138.0
TLS3_k127_3712397_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000003009 77.0
TLS3_k127_3712397_4 gas vesicle protein - - - 0.000007097 54.0
TLS3_k127_3714125_0 Belongs to the ClpA ClpB family K03696 - - 1.746e-210 663.0
TLS3_k127_3714125_1 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0015031,GO:0015399,GO:0015405,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022804,GO:0022857,GO:0031224,GO:0032991,GO:0033036,GO:0042157,GO:0042160,GO:0042623,GO:0042626,GO:0042886,GO:0042953,GO:0043170,GO:0043190,GO:0043492,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901564,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000001429 154.0
TLS3_k127_373600_0 Alanine-glyoxylate amino-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007975 437.0
TLS3_k127_373600_1 4-Hydroxyphenylpyruvate dioxygenase K00457,K16421 GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27,1.13.11.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 357.0
TLS3_k127_373600_2 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 304.0
TLS3_k127_373600_3 TIGRFAM type 2 lantibiotic, mersacidin lichenicidin family - - - 0.00000000000002515 76.0
TLS3_k127_373600_4 TIGRFAM type 2 lantibiotic, mersacidin lichenicidin family - - - 0.000000000001305 70.0
TLS3_k127_3739414_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 368.0
TLS3_k127_3739414_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 347.0
TLS3_k127_3739414_2 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 290.0
TLS3_k127_3739414_3 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000001596 178.0
TLS3_k127_3739414_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000003485 144.0
TLS3_k127_3739414_5 chromosome segregation K03497 - - 0.0000000000000007036 79.0
TLS3_k127_374250_0 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002413 282.0
TLS3_k127_374250_1 BadF BadG BcrA BcrD - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000004386 161.0
TLS3_k127_374250_2 LysR substrate binding domain - - - 0.00000000000000000000000005449 112.0
TLS3_k127_3748682_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 462.0
TLS3_k127_3748682_1 AcrB/AcrD/AcrF family K03296 - - 0.0000000000000000000000000005243 126.0
TLS3_k127_3748682_2 Belongs to the phosphoglycerate kinase family K00927 GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 0.00000000000000000000000008406 108.0
TLS3_k127_3761317_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 380.0
TLS3_k127_3761317_1 Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000001509 183.0
TLS3_k127_3761317_2 radical SAM domain protein - - - 0.0000000000000000000000000000001481 125.0
TLS3_k127_3766941_0 Peptidase family M3 K01284 - 3.4.15.5 2.197e-230 723.0
TLS3_k127_3766941_1 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 301.0
TLS3_k127_3766941_2 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000001531 179.0
TLS3_k127_3800666_0 cellulose binding - - - 0.0 1295.0
TLS3_k127_3800666_1 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 506.0
TLS3_k127_3800666_2 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000001362 249.0
TLS3_k127_3800666_3 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000006659 190.0
TLS3_k127_3809868_0 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 501.0
TLS3_k127_3809868_1 'ABC-type proline glycine betaine transport K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004603 312.0
TLS3_k127_3809868_2 Histidine-specific methyltransferase, SAM-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 297.0
TLS3_k127_3809868_3 Protein tyrosine kinase K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000002412 215.0
TLS3_k127_3809868_4 Tyrosine phosphatase family - - - 0.000000000000000000000000000009838 126.0
TLS3_k127_3809868_5 Protein of unknown function (DUF3616) - - - 0.00000000000000000000000008148 118.0
TLS3_k127_3809868_6 VWA domain containing CoxE-like protein - - - 0.0008765 51.0
TLS3_k127_3814563_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 1.557e-315 994.0
TLS3_k127_3814563_1 Filamentation induced by cAMP protein fic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 344.0
TLS3_k127_382414_0 triphosphatase activity - - - 0.00000000000000000000000002855 115.0
TLS3_k127_382414_1 Protein of unknown function (DUF3298) - - - 0.00000000000000000000000004487 121.0
TLS3_k127_382414_2 Protein of unknown function (DUF2911) - - - 0.0000000000000001183 86.0
TLS3_k127_382414_3 Sugar (and other) transporter K08151 - - 0.0001516 48.0
TLS3_k127_3859061_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006662 394.0
TLS3_k127_3859061_1 PFAM TonB-dependent Receptor Plug - - - 0.00000000000000000000000000000000003324 142.0
TLS3_k127_3904489_0 PEP-utilising enzyme, mobile domain - - - 0.0 1069.0
TLS3_k127_3904489_1 Succinyl-CoA ligase like flavodoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 557.0
TLS3_k127_3904489_2 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005699 273.0
TLS3_k127_39047_0 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 573.0
TLS3_k127_39047_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000113 156.0
TLS3_k127_3917229_0 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007097 591.0
TLS3_k127_4002876_0 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 387.0
TLS3_k127_4002876_1 Transposase IS200 like - - - 0.0000000000000000000000000005952 113.0
TLS3_k127_4002876_2 - - - - 0.00000000000000001131 92.0
TLS3_k127_4018098_0 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 312.0
TLS3_k127_4018098_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000002119 99.0
TLS3_k127_4018098_2 transcriptional regulator, XRE family - - - 0.00004683 51.0
TLS3_k127_4018098_3 Helix-turn-helix XRE-family like proteins - - - 0.000458 48.0
TLS3_k127_4018490_0 lipopolysaccharide-transporting ATPase activity K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 312.0
TLS3_k127_4018490_1 RNA polymerase sigma-54 factor K03092 - - 0.00000000000004383 79.0
TLS3_k127_4018490_2 lipopolysaccharide transport K09774 - - 0.0000002544 57.0
TLS3_k127_4034172_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 317.0
TLS3_k127_4077030_0 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000002895 222.0
TLS3_k127_4077030_1 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02342,K03763 - 2.7.7.7 0.0000000000000000000000000000000000000008003 158.0
TLS3_k127_4077030_2 PFAM SNARE associated protein - - - 0.000000012 60.0
TLS3_k127_409681_0 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000001193 199.0
TLS3_k127_409681_1 sigma factor antagonist activity K04757 - 2.7.11.1 0.00000000000006134 78.0
TLS3_k127_409681_2 antisigma factor binding - - - 0.000000004948 62.0
TLS3_k127_409681_3 Protein of unknown function (DUF2662) - - - 0.000006488 57.0
TLS3_k127_410353_0 Amidohydrolase family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009432 549.0
TLS3_k127_410353_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005527 260.0
TLS3_k127_410353_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000003846 153.0
TLS3_k127_410353_3 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000000000000000000000003311 119.0
TLS3_k127_410353_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000001508 112.0
TLS3_k127_410353_5 SnoaL-like domain - - - 0.00000003535 63.0
TLS3_k127_410353_6 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.0003761 47.0
TLS3_k127_4111440_0 electron transfer activity K00428 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005806 282.0
TLS3_k127_4111440_1 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000009823 238.0
TLS3_k127_4111440_2 Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747 - 0.00000000000000000000000000000000000000000000214 170.0
TLS3_k127_4111440_3 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000001564 146.0
TLS3_k127_4111440_4 deaminated base DNA N-glycosylase activity K21929 - 3.2.2.27 0.00000000000000000000000000000000000008247 149.0
TLS3_k127_4111440_5 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000009358 149.0
TLS3_k127_4111440_6 Iron-sulphur cluster biosynthesis - - - 0.000000000000000000000000000001591 122.0
TLS3_k127_4111440_7 Glycine cleavage system T protein K00302,K00605 - 1.5.3.1,2.1.2.10 0.000000000002174 74.0
TLS3_k127_4111440_8 membrane - - - 0.00000001777 62.0
TLS3_k127_4137897_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005379 273.0
TLS3_k127_4137897_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001842 252.0
TLS3_k127_4137897_2 Domain of unknown function (DUF5117) - - - 0.00000000000000000000000000000000000000000000000000000000000169 218.0
TLS3_k127_4147531_0 peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 523.0
TLS3_k127_4147531_1 Tricorn protease C1 domain K08676 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 421.0
TLS3_k127_4147531_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 311.0
TLS3_k127_4147531_3 acetyltransferase - - - 0.0000000000000000000000000000000000000000002507 163.0
TLS3_k127_417454_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 572.0
TLS3_k127_417454_1 MacB-like periplasmic core domain - - - 0.00000000000000000000001213 102.0
TLS3_k127_4208094_0 dna ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 567.0
TLS3_k127_4208094_1 H( )-stimulated, divalent metal cation uptake system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 407.0
TLS3_k127_4208094_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000159 152.0
TLS3_k127_4208094_3 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.3.3.1 0.00004049 56.0
TLS3_k127_421994_0 Membrane-bound serine protease (ClpP class) K07403 - - 0.00000000000000000000000000000000000000000000000000000000001718 217.0
TLS3_k127_421994_1 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000002188 182.0
TLS3_k127_421994_2 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000002579 134.0
TLS3_k127_421994_3 AMP binding K06149 - - 0.00000000000001662 85.0
TLS3_k127_421994_4 Universal stress protein family - - - 0.00000000000009473 83.0
TLS3_k127_4227833_0 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000008993 213.0
TLS3_k127_426205_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 329.0
TLS3_k127_426205_1 protein methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000005125 190.0
TLS3_k127_4282948_0 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 378.0
TLS3_k127_4282948_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 379.0
TLS3_k127_4282948_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006853 355.0
TLS3_k127_4282948_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 327.0
TLS3_k127_4282948_4 PFAM peptidase K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 329.0
TLS3_k127_4282948_5 PFAM Aminotransferase, class I K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000003417 252.0
TLS3_k127_4282948_6 Belongs to the DapB family K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000009629 188.0
TLS3_k127_4282948_7 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000175 125.0
TLS3_k127_4308312_0 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 426.0
TLS3_k127_4308312_1 SAM-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 355.0
TLS3_k127_4314046_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 319.0
TLS3_k127_4314046_1 Enoyl-(Acyl carrier protein) reductase K00034,K03366 - 1.1.1.304,1.1.1.47,1.1.1.76 0.00000000000000000000000000000000000000000000000000001966 196.0
TLS3_k127_4314046_2 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.0000000000000000000000000000000001512 148.0
TLS3_k127_4318784_0 Chaperone of endosialidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 310.0
TLS3_k127_4318784_1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase - - - 0.0000000000000000000000000000000000000000000000006045 181.0
TLS3_k127_4318784_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.0000000000000000000000000000000000000001995 149.0
TLS3_k127_4318784_3 cell wall surface anchor family protein - - - 0.000000000000000000000000001596 128.0
TLS3_k127_4318890_0 amino acid transport K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 511.0
TLS3_k127_4318890_1 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 339.0
TLS3_k127_4318890_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00007896 53.0
TLS3_k127_43237_0 Amidohydrolase family - - - 6.122e-217 681.0
TLS3_k127_43237_1 2OG-Fe(II) oxygenase superfamily K07394 - - 0.0000000000000000000000000000000000000000000000217 179.0
TLS3_k127_43237_2 - - - - 0.0000000000000000000000006456 111.0
TLS3_k127_43237_3 Uncharacterized conserved protein (DUF2277) - - - 0.000000005139 57.0
TLS3_k127_4327945_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 421.0
TLS3_k127_4327945_1 zinc-ribbon domain - - - 0.00000000000000001043 92.0
TLS3_k127_4327945_2 PFAM Phosphomethylpyrimidine kinase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000001792 50.0
TLS3_k127_4332542_0 COGs COG3321 Polyketide synthase modules and related protein - - - 1.342e-203 641.0
TLS3_k127_4332542_1 Non-ribosomal peptide synthetase modules and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 344.0
TLS3_k127_4332542_2 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K00836,K06136,K06137,K06138 GO:0005575,GO:0005576 1.3.3.11,2.6.1.76 0.000000000000000000000000000000000000000000000000000000000001141 218.0
TLS3_k127_434008_0 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 406.0
TLS3_k127_434008_1 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004175 257.0
TLS3_k127_4344987_0 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 314.0
TLS3_k127_4344987_1 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000006977 265.0
TLS3_k127_4344987_2 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000004301 140.0
TLS3_k127_4344987_3 TIGRFAM diguanylate cyclase (GGDEF) domain K21019 - 2.7.7.65 0.00000000000000000000169 108.0
TLS3_k127_4344987_4 Tetratricopeptide repeat - - - 0.00001651 53.0
TLS3_k127_4348744_0 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 587.0
TLS3_k127_4349993_0 Belongs to the glycosyl hydrolase 2 family - - - 1.282e-253 794.0
TLS3_k127_4349993_1 PFAM UDP-galactopyranose mutase, C-terminal K01854 - 5.4.99.9 4.659e-205 643.0
TLS3_k127_4349993_2 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 410.0
TLS3_k127_4349993_3 PFAM UDP-galactopyranose mutase, C-terminal K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 362.0
TLS3_k127_4349993_4 conserved protein (COG2071) K09166 - - 0.00000000000000000000000000000000000000000000000000000002537 207.0
TLS3_k127_4349993_5 Predicted membrane protein (DUF2231) - - - 0.00000000000000000000000000000000000000000000000000003376 193.0
TLS3_k127_4360978_0 domain protein - - - 3.376e-303 957.0
TLS3_k127_4360978_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 301.0
TLS3_k127_4370792_0 phosphorylase K00688 - 2.4.1.1 4.322e-210 667.0
TLS3_k127_4370792_1 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000002838 206.0
TLS3_k127_4372484_0 Glycosyl transferase, family 2 K10012,K12999,K13670 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 387.0
TLS3_k127_4372484_1 WbqC-like protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 338.0
TLS3_k127_4372484_2 PFAM ABC transporter related K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 338.0
TLS3_k127_4372484_3 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002884 270.0
TLS3_k127_4372484_4 trans-aconitate 2-methyltransferase activity K02169 GO:0002682,GO:0002683,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0031347,GO:0031348,GO:0035821,GO:0043207,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046467,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0071704,GO:0075136,GO:0080134,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000001625 249.0
TLS3_k127_4372484_5 beta-fructofuranosidase activity - - - 0.00000000000000000000005898 101.0
TLS3_k127_4378162_0 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 363.0
TLS3_k127_4393091_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 424.0
TLS3_k127_4393091_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 412.0
TLS3_k127_4393091_2 SCO1/SenC K07152,K08976 - - 0.0000000000000000000000000000000000000000000000000000000000007695 217.0
TLS3_k127_4393091_3 SCO1/SenC K07152,K08976 - - 0.00000000000000000000000000000000000000000000000000000001009 209.0
TLS3_k127_4393091_4 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000002652 200.0
TLS3_k127_4393091_5 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000002353 69.0
TLS3_k127_4393091_6 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.0004148 51.0
TLS3_k127_4400510_0 nucleotide-excision repair K03701 - - 4.704e-268 847.0
TLS3_k127_4402828_0 PFAM NAD-dependent epimerase dehydratase K12454 - 5.1.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 483.0
TLS3_k127_4402828_1 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 392.0
TLS3_k127_4402828_2 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 347.0
TLS3_k127_4402828_3 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 336.0
TLS3_k127_4402828_4 CRP FNR family - - - 0.0000000000000000000000000000000000000000000000009398 184.0
TLS3_k127_4402828_5 SEC-C motif - - - 0.000000000000000001204 91.0
TLS3_k127_4405018_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004567,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010412,GO:0015923,GO:0016052,GO:0016787,GO:0016798,GO:0016985,GO:0016998,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046355,GO:0071554,GO:0071704,GO:1901575 3.2.1.78 0.000000000000000000000000000000000000000000000000000000335 212.0
TLS3_k127_4405018_1 elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000001536 192.0
TLS3_k127_4406766_0 lipopolysaccharide heptosyltransferase K02841,K02843 - - 0.0000000000000000000000000000000000000000000000000004013 198.0
TLS3_k127_4406766_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000002421 180.0
TLS3_k127_4406766_2 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000002671 161.0
TLS3_k127_4419677_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 596.0
TLS3_k127_4419677_1 cellulase activity - - - 0.0000000321 66.0
TLS3_k127_4421825_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 419.0
TLS3_k127_4421825_1 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K22024 - 1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 291.0
TLS3_k127_4421825_2 TIGRFAM YD repeat protein - - - 0.00000000000000000000000000000000003379 158.0
TLS3_k127_4421825_3 Hfq protein - - - 0.000000000000000000000009045 106.0
TLS3_k127_4421825_4 Histidine kinase - - - 0.00000000000000003243 87.0
TLS3_k127_4421825_5 Type II secretion system (T2SS), protein G K02456 - - 0.00004975 54.0
TLS3_k127_4421951_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 3.77e-204 644.0
TLS3_k127_4421951_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 406.0
TLS3_k127_4421951_2 Arginase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005799 255.0
TLS3_k127_4421951_3 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000434 143.0
TLS3_k127_4421951_4 - - - - 0.00001732 52.0
TLS3_k127_4424668_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 415.0
TLS3_k127_4424668_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.000000000000002812 86.0
TLS3_k127_4438924_0 Major Facilitator Superfamily K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002353 289.0
TLS3_k127_4438924_1 protease with the C-terminal PDZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001016 243.0
TLS3_k127_4438924_2 DoxX K15977 - - 0.00000000000000000000008514 103.0
TLS3_k127_4443567_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 308.0
TLS3_k127_4443567_1 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000001033 233.0
TLS3_k127_4443567_2 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000007311 196.0
TLS3_k127_4443567_3 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000001008 193.0
TLS3_k127_4443567_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000004042 130.0
TLS3_k127_4443567_5 Probable zinc-ribbon domain - - - 0.000000000000000000000004697 104.0
TLS3_k127_4447003_0 Alcohol dehydrogenase GroES-like domain K00008,K00148,K18369 - 1.1.1.14,1.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 577.0
TLS3_k127_4447003_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 314.0
TLS3_k127_4447003_2 Universal stress protein family - - - 0.000000000000000000000000000000000009006 148.0
TLS3_k127_4447003_3 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000007412 129.0
TLS3_k127_4447003_4 SPTR Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein K07005 - - 0.00000000000000000001111 97.0
TLS3_k127_4447003_5 AMP binding - - - 0.0000000000000000001145 96.0
TLS3_k127_4447003_6 DnaK suppressor protein K06204 - - 0.00000008218 62.0
TLS3_k127_4447003_7 Universal stress protein - - - 0.00005887 53.0
TLS3_k127_4447761_0 PFAM NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 474.0
TLS3_k127_4447761_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 418.0
TLS3_k127_4447761_2 Rubrerythrin K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 282.0
TLS3_k127_4447761_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000008148 200.0
TLS3_k127_4447761_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000726 134.0
TLS3_k127_4447761_5 membrane protein (homolog of Drosophila rhomboid) K19225 - 3.4.21.105 0.0000000000000000000000000000002523 138.0
TLS3_k127_4447761_6 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000001596 65.0
TLS3_k127_4448322_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 321.0
TLS3_k127_4448322_1 Formyl transferase K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000001959 196.0
TLS3_k127_4448322_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000001611 63.0
TLS3_k127_4448336_0 Arsenical pump-driving ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000002543 205.0
TLS3_k127_4448336_1 Gas vesicle synthesis protein GvpL/GvpF - - - 0.000000000000000000000000000000000006238 147.0
TLS3_k127_4448336_2 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure - - - 0.0000000000000000000000000000001938 125.0
TLS3_k127_4448336_3 Gas vesicle protein K - - - 0.00000000000000000000000000002343 121.0
TLS3_k127_4448336_4 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth - - - 0.000000000000000000000000008027 114.0
TLS3_k127_4448336_5 Gas vesicle synthesis protein GvpL/GvpF - - - 0.000000000000000008282 93.0
TLS3_k127_4448336_6 gas vesicle protein - - - 0.00000000000838 68.0
TLS3_k127_4457507_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 419.0
TLS3_k127_4457507_1 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 390.0
TLS3_k127_4457507_2 TIR domain - - - 0.00000000000000000000000009816 119.0
TLS3_k127_4462534_0 PFAM Prolyl oligopeptidase family - - - 1.26e-285 890.0
TLS3_k127_4462534_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000003663 250.0
TLS3_k127_4462569_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 497.0
TLS3_k127_4462569_1 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 296.0
TLS3_k127_4462569_2 Beta-lactamase - - - 0.00000000000000001913 93.0
TLS3_k127_4475643_0 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007856 319.0
TLS3_k127_4477701_0 Carboxypeptidase regulatory-like domain - - - 7.656e-214 700.0
TLS3_k127_4477701_1 Lanthionine synthetase C-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 486.0
TLS3_k127_4477701_2 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 372.0
TLS3_k127_4477701_3 Participates in transcription elongation, termination and antitermination - - - 0.00000000000000000000000000000000000000000000000000000001003 213.0
TLS3_k127_4484477_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 549.0
TLS3_k127_4484477_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 296.0
TLS3_k127_4484477_2 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001914 263.0
TLS3_k127_4491162_0 PFAM Organic solvent tolerance protein K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005132 281.0
TLS3_k127_4491162_1 Reprolysin (M12B) family zinc metalloprotease - - - 0.000000000000001697 88.0
TLS3_k127_4491404_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 576.0
TLS3_k127_4491404_1 Cyclomaltodextrinase, N-terminal K21575 - 3.2.1.135 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 426.0
TLS3_k127_4491404_2 Aamy_C - - - 0.00004319 48.0
TLS3_k127_4501646_0 Vault protein inter-alpha-trypsin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007989 412.0
TLS3_k127_4501646_1 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000002135 187.0
TLS3_k127_4501646_2 - - - - 0.00000000000000000000000000024 120.0
TLS3_k127_450727_0 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 471.0
TLS3_k127_450727_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 386.0
TLS3_k127_450727_2 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000002547 163.0
TLS3_k127_450727_3 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000009675 93.0
TLS3_k127_450727_4 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000012 102.0
TLS3_k127_4521136_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.955e-228 714.0
TLS3_k127_4521136_1 - - - - 0.0000000000000000000000000000000000000000000166 166.0
TLS3_k127_4532627_0 Zinc carboxypeptidase - - - 5.405e-218 700.0
TLS3_k127_4532627_1 iron-nicotianamine transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000003879 233.0
TLS3_k127_4536735_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 431.0
TLS3_k127_4536735_1 Hsp70 protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 354.0
TLS3_k127_4542668_0 Glycosyltransferase 36 associated - - - 2.283e-298 929.0
TLS3_k127_4553429_0 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000000000000000000001307 225.0
TLS3_k127_4553429_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000001356 210.0
TLS3_k127_4553429_2 HAD-superfamily hydrolase subfamily IA, variant 3 K01091,K01838 - 3.1.3.18,5.4.2.6 0.00000000000000000000000000000000008893 141.0
TLS3_k127_4553429_3 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000002426 94.0
TLS3_k127_4553563_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1113.0
TLS3_k127_4553563_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 379.0
TLS3_k127_4553563_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000003443 115.0
TLS3_k127_4553563_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000003466 96.0
TLS3_k127_4553563_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.0000000000000000002065 96.0
TLS3_k127_4557182_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008261 400.0
TLS3_k127_4557182_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000003423 61.0
TLS3_k127_4560470_0 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000002607 234.0
TLS3_k127_4560470_1 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000001948 239.0
TLS3_k127_4560470_2 Pilus assembly protein, PilO K02664 - - 0.000000002131 67.0
TLS3_k127_4581521_0 PLD-like domain K06131 - - 8.882e-212 668.0
TLS3_k127_4581521_1 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001423 264.0
TLS3_k127_4581521_2 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003397 263.0
TLS3_k127_4581521_3 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000003164 151.0
TLS3_k127_4586749_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000007965 246.0
TLS3_k127_4586749_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000007997 173.0
TLS3_k127_4589862_0 Sortilin, neurotensin receptor 3, - - - 0.0 1231.0
TLS3_k127_4589862_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000004863 217.0
TLS3_k127_45910_0 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 423.0
TLS3_k127_45910_1 Aldehyde dehydrogenase family K22445 - 1.2.99.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 421.0
TLS3_k127_4627237_0 ABC transporter K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 481.0
TLS3_k127_4627237_1 response regulator receiver K02483,K07658 - - 0.00000000000000000000000000000000000000000000000000000007218 203.0
TLS3_k127_4627237_2 Belongs to the ompA family - - - 0.0000000000000000000000000133 118.0
TLS3_k127_4627237_3 YicC domain protein - - - 0.00000000000302 68.0
TLS3_k127_4632905_0 AAA domain (dynein-related subfamily) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 479.0
TLS3_k127_4632905_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 463.0
TLS3_k127_4632905_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 460.0
TLS3_k127_4632905_3 Radical SAM superfamily K06139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 344.0
TLS3_k127_4632905_4 - - - - 0.0000000000000000000000000000000000001356 161.0
TLS3_k127_4632905_5 - - - - 0.00000000000000000000000000008182 120.0
TLS3_k127_4632905_6 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000005256 84.0
TLS3_k127_4650883_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004813 265.0
TLS3_k127_4650883_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000906 76.0
TLS3_k127_4656418_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008366 397.0
TLS3_k127_4656418_1 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000001119 114.0
TLS3_k127_4658884_0 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009677 608.0
TLS3_k127_4658884_1 Highly conserved protein containing a thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 308.0
TLS3_k127_4662320_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000001084 186.0
TLS3_k127_4662320_1 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.000000000000000000000007892 113.0
TLS3_k127_4662320_2 Lipopolysaccharide-assembly - - - 0.0000000000001505 78.0
TLS3_k127_4679914_0 Replicative DNA helicase K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 435.0
TLS3_k127_4679914_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000002717 200.0
TLS3_k127_4679914_2 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000001992 150.0
TLS3_k127_4679914_3 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000001147 114.0
TLS3_k127_4679914_4 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000004139 96.0
TLS3_k127_4679914_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K07263 - - 0.00000000002599 76.0
TLS3_k127_4693211_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 398.0
TLS3_k127_4693211_1 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000002429 222.0
TLS3_k127_4693211_2 diguanylate cyclase - - - 0.000000000000000000000001483 108.0
TLS3_k127_4716999_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000004597 177.0
TLS3_k127_472776_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1169.0
TLS3_k127_4730168_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31,3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 323.0
TLS3_k127_4730168_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.000000000000000000004305 94.0
TLS3_k127_4739673_0 TonB-dependent Receptor Plug Domain K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 371.0
TLS3_k127_4751169_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 312.0
TLS3_k127_4751169_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000001881 240.0
TLS3_k127_4754833_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000004259 261.0
TLS3_k127_4754833_1 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000354 242.0
TLS3_k127_4754833_2 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000005094 148.0
TLS3_k127_4754833_3 - - - - 0.0000000000000000000000000000001704 125.0
TLS3_k127_4754833_4 methyltransferase - - - 0.0000000000000009008 88.0
TLS3_k127_4756217_0 Belongs to the xylose isomerase family K01805 - 5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 603.0
TLS3_k127_4756217_1 Condensation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 509.0
TLS3_k127_4756217_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 334.0
TLS3_k127_4756217_3 Clostripain family - - - 0.0000000000000000000000004294 121.0
TLS3_k127_4756217_4 ABC transporter transmembrane region K06160 - - 0.000000000001602 72.0
TLS3_k127_4756217_5 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - 0.0000000001508 68.0
TLS3_k127_4780208_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003918 273.0
TLS3_k127_4780208_1 TPM domain K06872 - - 0.000000009407 68.0
TLS3_k127_4799910_0 Glycosyl hydrolase family 47 K01230 - 3.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 553.0
TLS3_k127_4828252_0 Phage tail protein (Tail_P2_I) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 501.0
TLS3_k127_4828252_1 Tail protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001878 284.0
TLS3_k127_4830334_0 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009551 492.0
TLS3_k127_4830334_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006134 303.0
TLS3_k127_4831061_0 PFAM FAD dependent oxidoreductase - - - 4.791e-203 646.0
TLS3_k127_4831061_1 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 421.0
TLS3_k127_4831061_2 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 391.0
TLS3_k127_4831061_3 heat shock protein binding K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 332.0
TLS3_k127_4831061_4 Actin K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001769 276.0
TLS3_k127_4831061_5 Plasmid stabilization - - - 0.000000000000000000000000003972 112.0
TLS3_k127_4831061_6 - - - - 0.0000000000000005877 80.0
TLS3_k127_4831061_7 - - - - 0.000000003385 61.0
TLS3_k127_4836569_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 336.0
TLS3_k127_4836569_1 PepSY-associated TM region - - - 0.000000000000000273 85.0
TLS3_k127_4862195_0 cellulose binding - - - 2.008e-221 692.0
TLS3_k127_4862195_1 PFAM beta-lactamase K17836 - 3.5.2.6 0.00000000000000000000000000000000000000005329 154.0
TLS3_k127_4862195_2 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.00000000000000000000000000000000000001574 147.0
TLS3_k127_4862195_3 Transposase IS200 like K07491 - - 0.0000000008459 68.0
TLS3_k127_4880323_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 387.0
TLS3_k127_4880323_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006513 379.0
TLS3_k127_4880323_2 Multicopper oxidase - - - 0.00000000000000000000000000000003748 132.0
TLS3_k127_4913304_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 504.0
TLS3_k127_4913304_1 Mur ligase middle domain K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 315.0
TLS3_k127_4913304_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000002986 147.0
TLS3_k127_4972343_0 AMP-binding enzyme K04110 - 6.2.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006762 387.0
TLS3_k127_4972343_1 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000002373 166.0
TLS3_k127_4984427_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 395.0
TLS3_k127_4984427_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 353.0
TLS3_k127_4984427_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 306.0
TLS3_k127_4984427_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000000001064 207.0
TLS3_k127_4984427_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - 0.00005419 51.0
TLS3_k127_4994957_0 PFAM Pyridoxal-dependent decarboxylase conserved domain K01580,K01593,K13745 - 4.1.1.105,4.1.1.15,4.1.1.28,4.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 578.0
TLS3_k127_4994957_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 330.0
TLS3_k127_4994957_2 3'(2'),5'-bisphosphate nucleotidase activity K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000001848 239.0
TLS3_k127_4994957_3 Protein of unknown function (DUF962) - - - 0.00000000000000000000000000000000002959 138.0
TLS3_k127_4994957_4 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000008779 95.0
TLS3_k127_5019341_0 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 376.0
TLS3_k127_5019341_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002937 281.0
TLS3_k127_5019341_2 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 GO:0000726,GO:0003674,GO:0003824,GO:0003953,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006464,GO:0006471,GO:0006476,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016787,GO:0016798,GO:0016799,GO:0019213,GO:0019538,GO:0030312,GO:0033554,GO:0033558,GO:0034641,GO:0034979,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070213,GO:0071214,GO:0071478,GO:0071479,GO:0071704,GO:0071944,GO:0090304,GO:0098732,GO:0104004,GO:0140096,GO:1901360,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000001035 225.0
TLS3_k127_5019341_3 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000002526 75.0
TLS3_k127_502354_0 Lipocalin-like domain K03098 - - 0.00000000000000000000000000000000000000000000001935 177.0
TLS3_k127_502354_1 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000000000000000000001823 171.0
TLS3_k127_502354_2 Histone methylation protein DOT1 - - - 0.00000000000000000000005592 102.0
TLS3_k127_502354_3 META domain - - - 0.0000000000000000002156 100.0
TLS3_k127_502397_0 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 453.0
TLS3_k127_502397_1 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002904 256.0
TLS3_k127_502397_2 4fe-4S ferredoxin, iron-sulfur binding domain protein K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0016625,GO:0016903,GO:0043873,GO:0050896,GO:0055114 1.2.7.1 0.000000000000000000000000000000000000000000000000000001787 194.0
TLS3_k127_5027388_0 Bacterial regulatory proteins, tetR family K13770 - - 0.0000000000000000000000000000000000000000000000001377 184.0
TLS3_k127_5027388_1 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000002805 178.0
TLS3_k127_5027388_2 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000006914 69.0
TLS3_k127_5110873_0 IgA Peptidase M64 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 562.0
TLS3_k127_5110873_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005084 273.0
TLS3_k127_512428_0 GAF domain - - - 0.000000000000000000000000000000000000000005584 174.0
TLS3_k127_512428_1 FecR protein - - - 0.0001173 54.0
TLS3_k127_5130616_0 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000003538 176.0
TLS3_k127_5130616_1 Protease prsW family - - - 0.00004516 48.0
TLS3_k127_5130616_2 Tetratricopeptide repeat - - - 0.0006747 52.0
TLS3_k127_5163310_0 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 306.0
TLS3_k127_5163310_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 285.0
TLS3_k127_5163310_2 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000001274 95.0
TLS3_k127_5179104_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.311e-224 703.0
TLS3_k127_5179104_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 479.0
TLS3_k127_5179104_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 396.0
TLS3_k127_5179104_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 336.0
TLS3_k127_5179104_4 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000001993 195.0
TLS3_k127_5179104_5 - - - - 0.0000000000000000000000000000000000000001701 154.0
TLS3_k127_5179104_6 - - - - 0.000000000000000000000000000002026 125.0
TLS3_k127_5179104_7 Predicted membrane protein (DUF2243) - - - 0.0000000000000363 75.0
TLS3_k127_5186254_0 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 424.0
TLS3_k127_5186254_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005334 258.0
TLS3_k127_5186254_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000005552 94.0
TLS3_k127_5186254_3 DnaJ molecular chaperone homology domain K09523 - - 0.000000000005048 73.0
TLS3_k127_5186254_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000003711 57.0
TLS3_k127_5211592_0 Large extracellular alpha-helical protein K06894 - - 0.0000000000000000000000000000000000000000000000000000000000000000003952 246.0
TLS3_k127_5224165_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 3.122e-257 811.0
TLS3_k127_5236566_0 Exodeoxyribonuclease iii K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 295.0
TLS3_k127_5236566_1 Peptidase dimerisation domain K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 295.0
TLS3_k127_5236566_2 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.00000000000000000000000000000000000000000002679 163.0
TLS3_k127_5236566_3 4Fe-4S dicluster domain K17723 - 1.3.1.1 0.00000000000000000000000000000000003786 138.0
TLS3_k127_5263222_0 actin binding - - - 0.000000000000000000000000000000000000000000009428 180.0
TLS3_k127_5264059_0 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 463.0
TLS3_k127_5264059_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000006725 238.0
TLS3_k127_5264059_2 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0008668 42.0
TLS3_k127_5265401_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K18331 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008582 403.0
TLS3_k127_5265401_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000024 260.0
TLS3_k127_5265401_2 2 iron, 2 sulfur cluster binding K00334,K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000002104 193.0
TLS3_k127_5269715_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 555.0
TLS3_k127_5269715_1 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007454 510.0
TLS3_k127_5269715_2 Peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 389.0
TLS3_k127_5269715_3 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000009271 192.0
TLS3_k127_5269715_4 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000002859 100.0
TLS3_k127_5269715_5 protocatechuate 3,4-dioxygenase activity - - - 0.0002316 45.0
TLS3_k127_5271629_0 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component K09014 - - 5.048e-252 784.0
TLS3_k127_5271629_1 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 491.0
TLS3_k127_5271629_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 329.0
TLS3_k127_5271629_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004626 283.0
TLS3_k127_5271629_4 Phosphoribulokinase / Uridine kinase family K00855,K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000006143 252.0
TLS3_k127_5271629_5 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000001259 173.0
TLS3_k127_5271629_6 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.00000000000000000000000000000000000000000002462 166.0
TLS3_k127_5271629_7 Transcriptional regulator - - - 0.00000000000000000000005407 104.0
TLS3_k127_5271629_8 Peptidase, M56 - - - 0.000001434 60.0
TLS3_k127_5272282_0 MFS/sugar transport protein K16211 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 348.0
TLS3_k127_5272282_1 Alpha amylase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 303.0
TLS3_k127_5276004_0 Pfam:N_methyl_2 K02456 - - 0.000000000000000000000000001088 117.0
TLS3_k127_5276004_1 General secretion pathway protein K02453 - - 0.000000000006773 78.0
TLS3_k127_5276004_2 Pilus assembly protein K02662 - - 0.000001378 59.0
TLS3_k127_5277928_0 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000001273 246.0
TLS3_k127_5277928_1 Unusual protein kinase - - - 0.000000000000000000000000000000001948 138.0
TLS3_k127_5279375_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003584 262.0
TLS3_k127_5279375_1 Putative adhesin - - - 0.0000000117 68.0
TLS3_k127_5286994_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 394.0
TLS3_k127_5286994_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000002096 68.0
TLS3_k127_5289223_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008404 325.0
TLS3_k127_5289223_1 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000203 221.0
TLS3_k127_5289223_2 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000007839 191.0
TLS3_k127_5289223_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000001776 186.0
TLS3_k127_5289223_4 LemA family K03744 - - 0.0000000000000000000000000000000000000000000002204 174.0
TLS3_k127_5289223_5 BMC K04027 - - 0.0000000000000000000000000000000001892 133.0
TLS3_k127_5289223_6 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.0000000000000000000000000000584 119.0
TLS3_k127_5289223_7 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.00000000000000000000004688 100.0
TLS3_k127_5289223_8 Ethanolamine utilisation protein EutN/carboxysome K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.0000000000001918 73.0
TLS3_k127_5289223_9 nucleotidyltransferase activity - - - 0.00000000003637 68.0
TLS3_k127_5296839_0 ATPases associated with a variety of cellular activities K10823,K10824 - 3.6.3.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 433.0
TLS3_k127_5296839_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 402.0
TLS3_k127_5296839_2 'ABC-type dipeptide oligopeptide nickel transport K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 357.0
TLS3_k127_5296839_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K15581 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000004693 61.0
TLS3_k127_5296839_4 Sensory domain found in PocR - - - 0.0000001693 59.0
TLS3_k127_5302438_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.537e-234 735.0
TLS3_k127_5302438_1 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 505.0
TLS3_k127_5302438_2 virion core protein, lumpy skin disease virus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 395.0
TLS3_k127_5302438_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 295.0
TLS3_k127_5302438_4 Methyltransferase domain - - - 0.0000000000000000000000000000009727 130.0
TLS3_k127_5302438_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000004146 117.0
TLS3_k127_5302438_6 VanZ like family - - - 0.00000000000000000000000002582 114.0
TLS3_k127_5302438_7 Belongs to the ParB family K03497 - - 0.000000000005925 70.0
TLS3_k127_5302438_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000006415 70.0
TLS3_k127_5302438_9 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000003657 55.0
TLS3_k127_5311331_0 PFAM D-aminoacylase, C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 538.0
TLS3_k127_5311331_1 esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001957 279.0
TLS3_k127_5311331_2 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000004858 194.0
TLS3_k127_5311331_3 cellulose binding - - - 0.0000000000000000000000000000000003087 135.0
TLS3_k127_5311331_4 Protein of unknown function (DUF433) - - - 0.000000000000000000000003846 103.0
TLS3_k127_5311331_5 - - - - 0.000007018 51.0
TLS3_k127_5311331_6 - - - - 0.00007463 45.0
TLS3_k127_5332064_0 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000008387 196.0
TLS3_k127_5332064_1 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000009575 153.0
TLS3_k127_5332064_2 Extradiol ring-cleavage dioxygenase class III protein subunit B K06990,K09141 - - 0.0000000000000000000000000003133 120.0
TLS3_k127_534006_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 437.0
TLS3_k127_534006_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000874 265.0
TLS3_k127_534006_2 Subtilase family - - - 0.0000000000000000000000000000000000000000001547 171.0
TLS3_k127_5341617_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 554.0
TLS3_k127_5341617_1 Conserved hypothetical protein 95 - - - 0.00000000000000000000000000000000000000000001021 169.0
TLS3_k127_5341617_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000001094 123.0
TLS3_k127_5369165_0 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 481.0
TLS3_k127_5369165_1 YtkA-like - - - 0.0000000000002022 72.0
TLS3_k127_5371140_0 class II (D K K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 602.0
TLS3_k127_5371140_1 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 287.0
TLS3_k127_5371140_2 PFAM aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.00000000000000000000000000000000001062 149.0
TLS3_k127_5371140_3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01476,K01480 GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 3.5.3.1,3.5.3.11 0.00000000002669 65.0
TLS3_k127_5371140_4 Nucleotide-diphospho-sugar transferase K03240 GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005851,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0019222,GO:0019538,GO:0019899,GO:0031323,GO:0031326,GO:0032045,GO:0032268,GO:0032991,GO:0034248,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051020,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0080090,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.00001668 51.0
TLS3_k127_5373248_0 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000128 254.0
TLS3_k127_5373248_1 Tetratricopeptide repeat - - - 0.00000000000000000000345 107.0
TLS3_k127_5373248_2 DinB superfamily - - - 0.0000000000002844 74.0
TLS3_k127_5379149_0 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009979 392.0
TLS3_k127_5379149_1 PFAM Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 373.0
TLS3_k127_5392179_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000003995 217.0
TLS3_k127_5392179_1 peptidase M15B and M15C DD-carboxypeptidase VanY - - - 0.00000000000000000000003983 110.0
TLS3_k127_5392179_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000002816 83.0
TLS3_k127_5392179_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000009751 69.0
TLS3_k127_5397282_0 FGGY family of carbohydrate kinases, C-terminal domain K00851 - 2.7.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 366.0
TLS3_k127_5398396_0 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 413.0
TLS3_k127_5398396_1 PFAM Glycosyl transferase, family K00756 - 2.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007547 405.0
TLS3_k127_5398396_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000005206 175.0
TLS3_k127_5398396_3 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.00000000000000000000000000000000000000000000007952 177.0
TLS3_k127_5398396_4 - - - - 0.0000000000000000000000000000000000000000000002513 171.0
TLS3_k127_5398396_5 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000001001 101.0
TLS3_k127_5398396_6 Protein of unknown function, DUF393 - - - 0.00000000000000000000002084 102.0
TLS3_k127_5405600_0 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003041 264.0
TLS3_k127_5405600_1 Peptidase family M50 K06402 - - 0.000000000000000000000000000000000000132 148.0
TLS3_k127_5407684_0 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000005647 214.0
TLS3_k127_5407684_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000006049 198.0
TLS3_k127_5407684_2 Histidine kinase K02668,K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000227 183.0
TLS3_k127_5407684_3 PFAM Outer membrane efflux protein - - - 0.00000000000000004548 96.0
TLS3_k127_5411035_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 529.0
TLS3_k127_5411035_1 Zn-dependent hydrolase, glyoxylase - - - 0.00000000000000000000000000000000000000000000000001963 192.0
TLS3_k127_5411035_2 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000002827 135.0
TLS3_k127_5411035_3 C4-type zinc ribbon domain K07164,K22391 - 3.5.4.16 0.0000000000000000000003276 106.0
TLS3_k127_5411035_4 NAD(P)H-binding K01784,K12448 - 5.1.3.2,5.1.3.5 0.0000001244 57.0
TLS3_k127_5424847_0 Domain of unknown function (DUF5117) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 538.0
TLS3_k127_544048_0 PFAM Formiminotransferase domain K00603,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000008158 254.0
TLS3_k127_544048_1 Stage II sporulation protein M - - - 0.000000000000000000000000000000000000000000000000000000000000000000004403 253.0
TLS3_k127_5463191_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.5 0.00000000000000000000000000000000000001426 153.0
TLS3_k127_5463191_1 LysM domain K01185,K02030,K04043 - 3.2.1.17 0.0000000003865 71.0
TLS3_k127_5463191_2 - - - - 0.0000001493 54.0
TLS3_k127_5463191_3 cobalamin-transporting ATPase activity - - - 0.0001442 51.0
TLS3_k127_5468952_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 310.0
TLS3_k127_5468952_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000003589 207.0
TLS3_k127_5468952_2 von Willebrand factor, type A - - - 0.0002844 47.0
TLS3_k127_5503368_0 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 499.0
TLS3_k127_5503368_1 Oxidoreductase NAD-binding domain - - - 0.0000004717 55.0
TLS3_k127_5506204_0 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 439.0
TLS3_k127_5506204_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 401.0
TLS3_k127_5506204_10 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000002346 82.0
TLS3_k127_5506204_2 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 366.0
TLS3_k127_5506204_3 response regulator receiver K03413 - - 0.00000000000000000000000000000000000000000000000000000000006984 216.0
TLS3_k127_5506204_4 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000002759 196.0
TLS3_k127_5506204_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000001896 184.0
TLS3_k127_5506204_6 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000002525 154.0
TLS3_k127_5506204_7 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000000002584 134.0
TLS3_k127_5506204_8 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.00000000000000000000008737 107.0
TLS3_k127_5506204_9 cell redox homeostasis K02199 - - 0.000000000000000000002938 102.0
TLS3_k127_5509485_0 Belongs to the GSP D family K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004325 284.0
TLS3_k127_5509485_1 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.000000000000000000000000000000000000000000000001529 185.0
TLS3_k127_5509485_2 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000002022 105.0
TLS3_k127_5509485_3 Type IV leader peptidase family K02278 - 3.4.23.43 0.0000009727 54.0
TLS3_k127_5519721_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 456.0
TLS3_k127_5519721_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 406.0
TLS3_k127_5519721_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000007103 169.0
TLS3_k127_5521639_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000226 216.0
TLS3_k127_5521639_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000279 173.0
TLS3_k127_5521639_2 Protein of unknown function (DUF2892) - - - 0.000000000000000001048 89.0
TLS3_k127_5524500_0 carbamoyl transferase, NodU family K00612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 354.0
TLS3_k127_5524500_1 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000003913 158.0
TLS3_k127_5524500_2 transferase activity, transferring glycosyl groups - - - 0.0005303 44.0
TLS3_k127_5526164_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 379.0
TLS3_k127_5526164_1 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 330.0
TLS3_k127_5526164_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000114 147.0
TLS3_k127_5533236_0 copper resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 340.0
TLS3_k127_5533236_1 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000001161 144.0
TLS3_k127_5533236_2 Protein of unknown function with PCYCGC motif - - - 0.0000000000000000001182 94.0
TLS3_k127_5542698_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.24e-263 831.0
TLS3_k127_5542698_1 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000002236 89.0
TLS3_k127_5557000_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 1.13e-223 724.0
TLS3_k127_5557000_1 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000003015 234.0
TLS3_k127_5559828_0 Belongs to the PEP-utilizing enzyme family K01006,K01007 - 2.7.9.1,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 404.0
TLS3_k127_5559828_1 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000004545 189.0
TLS3_k127_5564771_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008414 278.0
TLS3_k127_5564771_1 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001295 260.0
TLS3_k127_5564771_2 Transport permease protein K09690 - - 0.000000000000000000000000000000000000000000000000000000000812 211.0
TLS3_k127_5564771_3 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00001036 48.0
TLS3_k127_5566389_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000008341 271.0
TLS3_k127_5566389_1 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000001481 173.0
TLS3_k127_5590477_0 Pfam Ion transport protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 343.0
TLS3_k127_5590477_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 335.0
TLS3_k127_5590477_2 von Willebrand factor, type A - - - 0.000000000000000000000000000003506 137.0
TLS3_k127_5590477_3 Lanthionine synthetase C family protein - - - 0.000000000000003314 89.0
TLS3_k127_5599246_0 cellulose binding - - - 3.466e-216 691.0
TLS3_k127_5601918_0 Associated with various cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 378.0
TLS3_k127_5601918_1 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009282 354.0
TLS3_k127_5601918_2 COGs COG1975 Xanthine and CO dehydrogenase maturation factor XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000001155 244.0
TLS3_k127_5601918_3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000009693 163.0
TLS3_k127_5601918_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 0.0000000000000000000000000000009527 121.0
TLS3_k127_5601918_5 XdhC and CoxI family K07402 - - 0.0005723 46.0
TLS3_k127_5612568_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1280.0
TLS3_k127_5612635_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 423.0
TLS3_k127_5612635_1 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003884 248.0
TLS3_k127_5612635_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0003133 43.0
TLS3_k127_561940_0 efflux transmembrane transporter activity K02004 - - 1.112e-234 754.0
TLS3_k127_561940_1 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000000486 174.0
TLS3_k127_561940_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000002797 100.0
TLS3_k127_5636409_0 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 465.0
TLS3_k127_5636409_1 acetyltransferase - - - 0.00000000000000001052 84.0
TLS3_k127_5660183_0 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 464.0
TLS3_k127_5660183_1 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000001814 191.0
TLS3_k127_5700197_0 PFAM DNA mismatch repair protein MutS domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 526.0
TLS3_k127_5700197_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005008 272.0
TLS3_k127_5700197_2 enterobactin catabolic process - - - 0.00000000000000000008318 94.0
TLS3_k127_5706532_0 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 368.0
TLS3_k127_5706532_1 - - - - 0.00000000000000603 87.0
TLS3_k127_5706532_2 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000001004 73.0
TLS3_k127_5706532_3 Type IV pilus biogenesis K02656 - - 0.000000132 62.0
TLS3_k127_5706532_4 Domain of unknown function (DUF4129) - - - 0.000001866 59.0
TLS3_k127_5744298_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 426.0
TLS3_k127_5744298_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001058 249.0
TLS3_k127_5744298_2 PFAM penicillin-binding protein transpeptidase - - - 0.00000000000000000000000000000000000000000000000000000009198 217.0
TLS3_k127_5744298_3 Cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.0000000000000002012 87.0
TLS3_k127_575879_0 PFAM TonB-dependent Receptor Plug - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 314.0
TLS3_k127_575879_1 PFAM D-aminoacylase, C-terminal region K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000003966 234.0
TLS3_k127_575879_2 Glycosyl hydrolase-like 10 - - - 0.000000000000000000000000000000000000000000006231 177.0
TLS3_k127_5778736_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 595.0
TLS3_k127_5778736_1 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 455.0
TLS3_k127_5778736_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000001993 94.0
TLS3_k127_5778736_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000003349 51.0
TLS3_k127_5812599_0 helicase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 558.0
TLS3_k127_5812599_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000008505 181.0
TLS3_k127_5824055_0 chaperone-mediated protein folding - - - 0.00000000000000000000000000000000000000000000000000000000000002738 238.0
TLS3_k127_5824055_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000002814 144.0
TLS3_k127_5824055_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000002497 114.0
TLS3_k127_5837587_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 316.0
TLS3_k127_5837587_1 Tetratricopeptide repeat - - - 0.000000000000008185 87.0
TLS3_k127_5905523_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 3.766e-233 736.0
TLS3_k127_5905523_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000003558 237.0
TLS3_k127_5948810_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1164.0
TLS3_k127_5948810_1 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000001792 197.0
TLS3_k127_5948810_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.000000000000000000000000000000000000000000003475 180.0
TLS3_k127_5948810_3 - - - - 0.00000000000000000000000001229 116.0
TLS3_k127_5948810_4 Outer membrane efflux protein K15725 - - 0.00000000000000000000001309 115.0
TLS3_k127_5948810_5 - - - - 0.00000001143 63.0
TLS3_k127_5950074_0 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000001639 153.0
TLS3_k127_5950074_1 Bacterial PH domain K08981 - - 0.0000000004579 68.0
TLS3_k127_5950074_2 Putative peptidoglycan binding domain - - - 0.000001175 55.0
TLS3_k127_5954260_0 N-acetyldiaminopimelate deacetylase activity K12941 - - 2.797e-236 740.0
TLS3_k127_5954260_1 Transporter-associated region K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 531.0
TLS3_k127_5954260_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 477.0
TLS3_k127_6020257_0 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000002142 163.0
TLS3_k127_6020257_1 - - - - 0.00000000000000009898 83.0
TLS3_k127_6020257_2 serine-type aminopeptidase activity K02030,K14475 - - 0.000000000000211 76.0
TLS3_k127_6020257_3 Peptidase M28 - - - 0.000003531 54.0
TLS3_k127_6020257_4 Ferredoxin K04755 - - 0.0001728 51.0
TLS3_k127_6026146_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000002808 156.0
TLS3_k127_6026146_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000003741 143.0
TLS3_k127_6026146_2 O-antigen ligase like membrane protein - - - 0.00000000000000000000001104 115.0
TLS3_k127_6031601_0 Polysaccharide biosynthesis protein K17947 - 5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 541.0
TLS3_k127_6031601_1 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000302 293.0
TLS3_k127_6031601_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002083 251.0
TLS3_k127_6031601_3 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000006567 236.0
TLS3_k127_6031601_4 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000498 112.0
TLS3_k127_6032222_0 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 627.0
TLS3_k127_6032222_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 477.0
TLS3_k127_6032222_2 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 381.0
TLS3_k127_6032222_3 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001593 255.0
TLS3_k127_6032222_4 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000002878 196.0
TLS3_k127_6032222_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000002199 187.0
TLS3_k127_6032222_6 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000000004742 106.0
TLS3_k127_6032222_7 mRNA binding - - - 0.00000000000000287 76.0
TLS3_k127_6033741_0 - - - - 0.0000000000000000000000000000000000000000000000000000002041 210.0
TLS3_k127_6033741_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K07291 - 2.7.8.34 0.000000000000000000000000000000000000000000000000000000231 201.0
TLS3_k127_6033741_2 Protein of unknown function (DUF1572) - - - 0.0000000000000000000000000000000009147 140.0
TLS3_k127_6033741_3 - - - - 0.0000000000000000000000000003053 115.0
TLS3_k127_6033741_4 Protein of unknown function (DUF971) - - - 0.0000000000000000000000007634 107.0
TLS3_k127_6054803_0 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 578.0
TLS3_k127_6054803_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009255 520.0
TLS3_k127_6054803_2 Haem-degrading - - - 0.0000000000000000582 91.0
TLS3_k127_6067270_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 513.0
TLS3_k127_6067270_1 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 454.0
TLS3_k127_6067270_2 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000002304 49.0
TLS3_k127_6084800_0 CHASE3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 353.0
TLS3_k127_6084800_1 Sigma-54 factor interaction domain-containing protein K07713 - - 0.0000000000000000000000001414 113.0
TLS3_k127_6087496_0 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 476.0
TLS3_k127_6087496_1 Isocitrate lyase K01637 - 4.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 385.0
TLS3_k127_6088036_0 Tetratricopeptide repeat - - - 0.0000000008312 71.0
TLS3_k127_6091203_0 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 445.0
TLS3_k127_6091203_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850,K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 406.0
TLS3_k127_6091203_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000002055 184.0
TLS3_k127_6091203_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000002937 162.0
TLS3_k127_6091203_4 - - - - 0.0000001514 56.0
TLS3_k127_6091203_5 - - - - 0.00002815 49.0
TLS3_k127_6095817_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 453.0
TLS3_k127_60965_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 323.0
TLS3_k127_60965_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 316.0
TLS3_k127_60965_2 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000000000000000000007589 147.0
TLS3_k127_60965_3 - K01992 - - 0.00000000000000101 90.0
TLS3_k127_6099894_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 3.53e-254 793.0
TLS3_k127_6099894_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009402 518.0
TLS3_k127_6099894_2 Ornithine cyclodeaminase/mu-crystallin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 324.0
TLS3_k127_6099894_3 sequence-specific DNA binding K01697,K01738 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000002145 248.0
TLS3_k127_6099894_4 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000001912 235.0
TLS3_k127_6137034_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 381.0
TLS3_k127_6137034_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000008208 215.0
TLS3_k127_6137034_2 MerR HTH family regulatory protein K13640 - - 0.0000000000000000000000000000000000004649 143.0
TLS3_k127_6137034_3 Heat shock 70 kDa protein K04043 - - 0.0000000000106 68.0
TLS3_k127_6137182_0 Glycoside hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006263 292.0
TLS3_k127_6143535_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1151.0
TLS3_k127_6143535_1 COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K02619 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008696,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 4.1.3.38 0.000000000000000000005482 97.0
TLS3_k127_6152048_0 Oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001943 271.0
TLS3_k127_6152048_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000005689 239.0
TLS3_k127_6152048_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000002747 192.0
TLS3_k127_6157780_0 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 502.0
TLS3_k127_6157780_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 354.0
TLS3_k127_6157780_2 Protein of unknown function (DUF445) - - - 0.0000000006143 66.0
TLS3_k127_6163297_0 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 395.0
TLS3_k127_6163297_1 Capsular exopolysaccharide family K08252 - 2.7.10.1 0.00000000000000000000000000000000000004089 156.0
TLS3_k127_6163297_2 AAA domain K02450 - - 0.00000000000000000000000002976 114.0
TLS3_k127_6163297_3 PFAM Polysaccharide export protein K01991 - - 0.0000000000000000000005504 106.0
TLS3_k127_6163297_4 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000007499 103.0
TLS3_k127_6180769_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 597.0
TLS3_k127_6180769_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009672 302.0
TLS3_k127_6180769_2 amine dehydrogenase activity - - - 0.000000000627 70.0
TLS3_k127_6182044_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 5.168e-207 663.0
TLS3_k127_6182044_1 peptidase M20 K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 381.0
TLS3_k127_6182044_2 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000006934 173.0
TLS3_k127_6182044_3 Histidine kinase - - - 0.000000000000000000000000000000001601 141.0
TLS3_k127_6182044_4 Bacterial regulatory protein, Fis family - - - 0.000007562 48.0
TLS3_k127_6182044_5 - - - - 0.0003772 49.0
TLS3_k127_6186631_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000271 280.0
TLS3_k127_6186631_1 Methyltransferase domain - - - 0.0001778 53.0
TLS3_k127_6196080_0 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 398.0
TLS3_k127_6196080_1 Dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 297.0
TLS3_k127_6196080_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000001672 139.0
TLS3_k127_6213336_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000002042 274.0
TLS3_k127_6213336_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000005323 255.0
TLS3_k127_6213336_2 Serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0008612 50.0
TLS3_k127_6220021_0 AcrB/AcrD/AcrF family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 447.0
TLS3_k127_6220021_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000005055 232.0
TLS3_k127_6220021_2 Predicted nucleotide-binding protein containing TIR-like domain - - - 0.00000000000000000000000000000000000000000000000000004762 199.0
TLS3_k127_6220021_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000004927 168.0
TLS3_k127_6227774_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 540.0
TLS3_k127_6227774_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 327.0
TLS3_k127_6227774_2 Oxidoreductase, molybdopterin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001279 271.0
TLS3_k127_6227774_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000009715 164.0
TLS3_k127_6227774_4 PFAM DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000005126 141.0
TLS3_k127_6227774_5 Domain of unknown function (DUF4870) - - - 0.0000000000000000000000007286 109.0
TLS3_k127_6227774_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000002575 101.0
TLS3_k127_6227774_7 VKc - - - 0.000000001608 64.0
TLS3_k127_6242647_0 PFAM Glycosyl hydrolase family 3 C terminal domain - - - 7.966e-262 827.0
TLS3_k127_6242647_1 Putative carbohydrate binding domain K12373 - 3.2.1.52 2.573e-229 727.0
TLS3_k127_6242647_2 Lactonase, 7-bladed beta-propeller K07404 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 415.0
TLS3_k127_6242647_3 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 302.0
TLS3_k127_6242647_4 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007182 276.0
TLS3_k127_6260315_0 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 389.0
TLS3_k127_6260315_1 Transcriptional regulator, AbiEi antitoxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 322.0
TLS3_k127_6260315_2 self proteolysis - - - 0.00008326 45.0
TLS3_k127_6260315_3 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively - - - 0.0001514 48.0
TLS3_k127_6260315_4 TIGRFAM amino acid adenylation domain - - - 0.0005763 44.0
TLS3_k127_6261606_0 Peptidase family M49 - - - 3.418e-205 654.0
TLS3_k127_6261606_1 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000002828 124.0
TLS3_k127_6261606_2 Abhydrolase domain containing 18 - - - 0.000000000000000000000000000001449 125.0
TLS3_k127_6276110_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 532.0
TLS3_k127_6276110_1 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 305.0
TLS3_k127_6276110_2 Uracil DNA glycosylase superfamily K03649 - 3.2.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000003301 259.0
TLS3_k127_6276110_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001054 267.0
TLS3_k127_6276110_4 oxidoreductase activity - - - 0.00000000000000000000000000000000000000007631 173.0
TLS3_k127_6276110_5 protein histidine kinase activity - - - 0.0000000000000000000001718 102.0
TLS3_k127_6276110_6 PFAM Adenylate cyclase K05873 - 4.6.1.1 0.0000000000000000000601 101.0
TLS3_k127_6276280_0 Putative glutamine amidotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 379.0
TLS3_k127_6276280_1 Plasmid stabilization system - - - 0.0002187 46.0
TLS3_k127_6276280_2 Putative addiction module component - - - 0.0002902 47.0
TLS3_k127_6281689_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 536.0
TLS3_k127_6281689_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 485.0
TLS3_k127_6281689_2 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 404.0
TLS3_k127_6281689_3 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000001092 226.0
TLS3_k127_6295664_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000745 230.0
TLS3_k127_6295664_1 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000000000000000154 218.0
TLS3_k127_6295664_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000001471 178.0
TLS3_k127_6295664_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000666 126.0
TLS3_k127_6295664_4 Tfp pilus assembly protein FimV - - - 0.00000000001247 74.0
TLS3_k127_6295664_5 Dioxygenase - - - 0.0000000007917 63.0
TLS3_k127_6297097_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 430.0
TLS3_k127_6297097_1 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 360.0
TLS3_k127_6297097_2 conserved protein, contains double-stranded beta-helix domain - - - 0.0000000000000000000000000000000000000000000000000003355 187.0
TLS3_k127_6297097_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000006451 172.0
TLS3_k127_6338744_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.031e-281 876.0
TLS3_k127_6338744_1 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005399 259.0
TLS3_k127_6338744_2 Uncharacterised nucleotidyltransferase - - - 0.000000000000000000000000000000607 128.0
TLS3_k127_6360782_0 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 474.0
TLS3_k127_6360782_1 cellulase activity - - - 0.0000000000000000002378 103.0
TLS3_k127_6360782_2 Outer membrane protein (OmpH-like) K06142 - - 0.000002754 57.0
TLS3_k127_6368623_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 378.0
TLS3_k127_6368623_1 NAD-dependent K08678 - 4.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 297.0
TLS3_k127_6368623_2 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000001249 63.0
TLS3_k127_6395640_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 418.0
TLS3_k127_6395640_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000001986 232.0
TLS3_k127_6395640_2 Formyl transferase K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000002554 218.0
TLS3_k127_6395640_3 domain protein K02238 - - 0.0000000000000000000000000000000000000000000000000001041 200.0
TLS3_k127_6403128_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 389.0
TLS3_k127_6403128_1 Belongs to the ClpA ClpB family K03695,K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007685 279.0
TLS3_k127_6427978_0 glycyl-tRNA aminoacylation K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 505.0
TLS3_k127_6433658_0 LVIVD repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 426.0
TLS3_k127_6433658_1 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000000000000000000000000000000000000000000000002094 192.0
TLS3_k127_6433658_2 ECF sigma factor - - - 0.00000000000000000000000000000000000002079 151.0
TLS3_k127_6433658_3 amine dehydrogenase activity - - - 0.0000000000000000001032 89.0
TLS3_k127_6470778_0 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 352.0
TLS3_k127_6470778_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000177 292.0
TLS3_k127_6470778_2 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000000002583 177.0
TLS3_k127_6470778_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000002601 175.0
TLS3_k127_6470778_4 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000004098 109.0
TLS3_k127_6470778_5 Protein of unknown function, DUF255 K04084 - 1.8.1.8 0.000000000000072 78.0
TLS3_k127_6507486_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 406.0
TLS3_k127_6507486_1 Pfam:KaiC K08482 - - 0.0000000000000000000000000000000000000000000000000000000000001048 220.0
TLS3_k127_6507486_2 PFAM KaiB domain K08481 - - 0.0000000000000000000000000000000000000002022 154.0
TLS3_k127_6507486_3 KaiB K08481 - - 0.0000000000000000000000000005648 120.0
TLS3_k127_6520923_0 Calcineurin-like phosphoesterase K14379 - 3.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000001499 259.0
TLS3_k127_6520923_1 chaperone-mediated protein folding - - - 0.00000000000000000000000000000000000000000000000000000003285 218.0
TLS3_k127_6520923_2 - - - - 0.000000001534 67.0
TLS3_k127_6632996_0 PFAM Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 439.0
TLS3_k127_6632996_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 438.0
TLS3_k127_6632996_2 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 358.0
TLS3_k127_6632996_3 - - - - 0.0000000000000000000000000007236 118.0
TLS3_k127_6632996_4 Site-specific recombinase, phage integrase family - - - 0.00001084 52.0
TLS3_k127_6632996_5 ZIP Zinc transporter K16267 - - 0.0001075 47.0
TLS3_k127_6634227_0 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 342.0
TLS3_k127_6634227_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates K05522 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.0000000000000000000000000000000000117 147.0
TLS3_k127_6634227_2 Belongs to the peptidase M12A family K08076 - 3.4.24.21 0.0000000000000000000007574 111.0
TLS3_k127_6634227_3 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.000005504 54.0
TLS3_k127_6643183_0 Acyclic terpene utilisation family protein AtuA - - - 2.095e-212 667.0
TLS3_k127_6643183_1 ABC transporter K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 527.0
TLS3_k127_6643183_2 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 434.0
TLS3_k127_6643183_3 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 404.0
TLS3_k127_6643183_4 ABC-type sugar transport system periplasmic component K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 392.0
TLS3_k127_6643183_5 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000004732 213.0
TLS3_k127_6643183_6 - - - - 0.0000000000000000000000000000000000000000004763 159.0
TLS3_k127_6643183_7 PAS domain - - - 0.0000000000000000000000004128 104.0
TLS3_k127_66606_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008209 368.0
TLS3_k127_66606_1 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.000000000000000000002604 98.0
TLS3_k127_6741859_0 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 357.0
TLS3_k127_6741859_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000004295 203.0
TLS3_k127_6741859_2 Protein of unknown function (DUF3108) - - - 0.00000001736 67.0
TLS3_k127_6741859_3 Protein of unknown function (DUF3108) - - - 0.000001148 61.0
TLS3_k127_676910_0 RNA polymerase, sigma-24 subunit, ECF subfamily K02405 - - 0.0000000000000000000000000000000000000000000000000000002103 201.0
TLS3_k127_676910_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000001986 128.0
TLS3_k127_6806008_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 307.0
TLS3_k127_6806008_1 Acyl transferase domain K00645,K15327,K15329,K15469 - 2.3.1.39 0.00000000000000000000000000000000000000000000000003814 182.0
TLS3_k127_6806008_2 carbamoyl transferase, NodU family K00612 - - 0.0000000000000000000000000000001146 126.0
TLS3_k127_6806008_3 Transcription termination factor nusG - - - 0.0000000000000000000000000000004474 128.0
TLS3_k127_6809534_0 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 440.0
TLS3_k127_6809534_1 Protein of unknown function (DUF445) - - - 0.000000000000142 83.0
TLS3_k127_6835710_0 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 421.0
TLS3_k127_6908309_0 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000000000000000005061 166.0
TLS3_k127_6908309_1 S1/P1 Nuclease - - - 0.00000000000000000001465 96.0
TLS3_k127_6908309_2 - - - - 0.00003749 51.0
TLS3_k127_6908328_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 422.0
TLS3_k127_6908328_1 PFAM ATPase associated with various cellular activities K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003479 270.0
TLS3_k127_6908328_2 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000002117 207.0
TLS3_k127_6911772_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 1.188e-244 777.0
TLS3_k127_6911772_1 - - - - 0.00000000000000000000000000000000005408 149.0
TLS3_k127_69255_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007536 484.0
TLS3_k127_69255_1 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 353.0
TLS3_k127_69255_2 TIGRFAM TonB family K03832 - - 0.0000000004605 66.0
TLS3_k127_69255_3 phosphorelay signal transduction system - - - 0.000000004349 67.0
TLS3_k127_6930379_0 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000085 180.0
TLS3_k127_6930379_1 Transglutaminase-like superfamily - - - 0.00000000000000000359 92.0
TLS3_k127_6936624_0 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 384.0
TLS3_k127_6936624_1 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 366.0
TLS3_k127_6936624_2 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000002323 184.0
TLS3_k127_6936624_3 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000003215 140.0
TLS3_k127_6936624_4 Belongs to the peptidase S1C family - - - 0.0000000000000000256 96.0
TLS3_k127_6937945_0 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 445.0
TLS3_k127_6937945_1 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009029 271.0
TLS3_k127_6937945_2 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000004508 130.0
TLS3_k127_6944365_0 permease K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007999 334.0
TLS3_k127_6944365_1 peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000000000000004841 220.0
TLS3_k127_6971718_0 Penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 505.0
TLS3_k127_6971718_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000006613 128.0
TLS3_k127_6971718_2 SNARE associated Golgi protein - - - 0.0000000000000000004253 95.0
TLS3_k127_6971718_3 - - - - 0.000000000178 71.0
TLS3_k127_6984094_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.509e-197 631.0
TLS3_k127_6984094_1 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.00000000000000000000000000000000000000000001074 170.0
TLS3_k127_7018892_0 Fic/DOC family N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 548.0
TLS3_k127_7018892_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 402.0
TLS3_k127_7018892_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.00005007 50.0
TLS3_k127_7018892_11 Restriction endonuclease K07448 - - 0.000393 48.0
TLS3_k127_7018892_12 Thioredoxin-like - - - 0.0005154 49.0
TLS3_k127_7018892_2 dihydrofolate reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 336.0
TLS3_k127_7018892_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 329.0
TLS3_k127_7018892_4 ASCH - - - 0.00000000000000000000000000000000000000000000000001592 184.0
TLS3_k127_7018892_5 transposition - - - 0.0000000000000000000000000000000000000000001396 168.0
TLS3_k127_7018892_6 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000009596 160.0
TLS3_k127_7018892_7 SnoaL-like domain K06893 - - 0.000000000000000000000000000000000002091 142.0
TLS3_k127_7018892_8 - - - - 0.000000000000000000000000009453 113.0
TLS3_k127_7018892_9 Restriction endonuclease K07448 - - 0.000000000001144 78.0
TLS3_k127_7020259_0 Major facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 368.0
TLS3_k127_7020259_1 DNA polymerase K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 338.0
TLS3_k127_7020259_2 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 295.0
TLS3_k127_7020259_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.000000000000000000000000000000000000000000000000000000000000000001189 232.0
TLS3_k127_7020259_4 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000004332 135.0
TLS3_k127_7020259_5 DinB family - - - 0.000004515 57.0
TLS3_k127_7033809_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.357e-205 646.0
TLS3_k127_7033809_1 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008543 516.0
TLS3_k127_7033809_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 372.0
TLS3_k127_7033973_0 Heat shock 70 kDa protein K04043 - - 1.206e-228 722.0
TLS3_k127_7033973_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000004006 260.0
TLS3_k127_7033973_2 nucleotide metabolic process - - - 0.000000000000000000000000000000000000000000000000000001717 199.0
TLS3_k127_7033973_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.000000000000000000000000000000000191 141.0
TLS3_k127_7034805_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 359.0
TLS3_k127_7034805_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 346.0
TLS3_k127_7034805_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000001773 251.0
TLS3_k127_7034805_3 PFAM Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000004264 234.0
TLS3_k127_7034805_4 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000000000000000000000000001015 206.0
TLS3_k127_7034805_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000004744 188.0
TLS3_k127_7034805_6 DnaJ molecular chaperone homology domain - - - 0.00000000000006365 80.0
TLS3_k127_7034805_7 - - - - 0.00000000001178 78.0
TLS3_k127_7048999_0 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000001205 197.0
TLS3_k127_7048999_1 surface antigen variable number - - - 0.0000000000000000000000000000000000000000000000000007261 210.0
TLS3_k127_7048999_2 PFAM Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000007313 183.0
TLS3_k127_7048999_3 peptidylprolyl isomerase K03771 - 5.2.1.8 0.000351 51.0
TLS3_k127_7052968_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 527.0
TLS3_k127_7052968_1 tRNA processing K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 297.0
TLS3_k127_7055977_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 377.0
TLS3_k127_7057581_0 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 390.0
TLS3_k127_7057581_1 Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 306.0
TLS3_k127_7066729_0 MviN-like protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 398.0
TLS3_k127_7066729_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000001424 155.0
TLS3_k127_7067501_0 major pilin protein fima - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 429.0
TLS3_k127_7067501_1 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 335.0
TLS3_k127_7067501_2 PFAM TM2 domain - - - 0.00000000000000000000000000004406 120.0
TLS3_k127_7067501_3 Protein of unknown function (DUF2752) - - - 0.000000000000000000000001029 108.0
TLS3_k127_7067501_4 - - - - 0.00000000000000000001579 97.0
TLS3_k127_7075496_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 310.0
TLS3_k127_7080575_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000002891 246.0
TLS3_k127_7080575_1 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000002268 222.0
TLS3_k127_7107036_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 361.0
TLS3_k127_7107036_1 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000003102 117.0
TLS3_k127_7111687_0 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 597.0
TLS3_k127_7111687_1 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 582.0
TLS3_k127_7111687_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 381.0
TLS3_k127_7111687_3 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001317 279.0
TLS3_k127_7111687_4 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001667 273.0
TLS3_k127_7111687_5 chorismate mutase K04518,K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000817 149.0
TLS3_k127_7111687_6 PFAM Chorismate mutase, type II - - - 0.000000000001429 72.0
TLS3_k127_7116262_0 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 344.0
TLS3_k127_7116262_1 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000007617 235.0
TLS3_k127_7116262_2 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000002958 181.0
TLS3_k127_7116262_3 peptide catabolic process K01256 - 3.4.11.2 0.00002088 58.0
TLS3_k127_7124802_0 Belongs to the peptidase S8 family K08651,K14645 - 3.4.21.66 3.545e-228 735.0
TLS3_k127_7124802_1 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 477.0
TLS3_k127_7124802_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000001187 261.0
TLS3_k127_713823_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 587.0
TLS3_k127_7169460_0 ASPIC and UnbV - - - 9.628e-228 726.0
TLS3_k127_7169460_1 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000005783 225.0
TLS3_k127_7169460_2 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000005794 229.0
TLS3_k127_7173072_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1084.0
TLS3_k127_7188699_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.347e-210 670.0
TLS3_k127_7188699_1 PFAM Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 554.0
TLS3_k127_7188699_2 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 380.0
TLS3_k127_7188699_3 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07083,K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008442 341.0
TLS3_k127_7188699_4 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 302.0
TLS3_k127_7188699_5 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007774 282.0
TLS3_k127_7188699_6 peptidyl-tyrosine sulfation K03217,K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001217 272.0
TLS3_k127_7188699_7 - - - - 0.00000000000000000000000000000000000000000000001044 186.0
TLS3_k127_7188699_8 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000385 161.0
TLS3_k127_7203190_0 Zn-dependent protease with chaperone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 385.0
TLS3_k127_7203190_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000001958 192.0
TLS3_k127_7222454_0 Carboxyl transferase domain - - - 8.174e-237 743.0
TLS3_k127_7222454_1 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 310.0
TLS3_k127_7222454_2 Zn peptidase - - - 0.000000000000000000000000000000000000000000000000000000007193 214.0
TLS3_k127_7222454_3 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000003144 102.0
TLS3_k127_7222454_4 - - - - 0.0000000000000000003035 96.0
TLS3_k127_7245868_0 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005772 419.0
TLS3_k127_7245868_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 373.0
TLS3_k127_7245868_2 PFAM Integral membrane protein TerC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 353.0
TLS3_k127_7245868_3 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 308.0
TLS3_k127_7245868_4 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001139 277.0
TLS3_k127_7245868_5 Putative lumazine-binding - - - 0.00000000000000000000003306 104.0
TLS3_k127_7245868_6 transcriptional - - - 0.000000000000000000001903 99.0
TLS3_k127_7245868_7 signal transduction histidine kinase - - - 0.0001133 44.0
TLS3_k127_7256825_0 Associated with various cellular activities K04748 - - 0.000000000000000000000000000000000000000000000007447 174.0
TLS3_k127_7256825_1 von Willebrand factor (vWF) type A domain K02448 - - 0.000000000000003054 89.0
TLS3_k127_7269521_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 484.0
TLS3_k127_7269521_2 DinB family - - - 0.0000000000001556 74.0
TLS3_k127_7300833_0 Forkhead associated domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 333.0
TLS3_k127_7300833_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002136 269.0
TLS3_k127_7300833_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000001433 141.0
TLS3_k127_7309208_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 7.158e-195 639.0
TLS3_k127_7309208_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005351 257.0
TLS3_k127_7309208_2 Thioesterase superfamily K07107 - - 0.000000000000000000000008344 106.0
TLS3_k127_7322108_0 PEP-utilising enzyme, N-terminal K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 395.0
TLS3_k127_7322108_1 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001158 253.0
TLS3_k127_7322108_2 PTS system fructose IIA component K02793,K02794,K02821 - 2.7.1.191,2.7.1.194 0.0000000000000000000000000000000002173 136.0
TLS3_k127_7322108_3 Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme. - - - 0.0001577 50.0
TLS3_k127_733328_0 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000802 271.0
TLS3_k127_733328_1 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004479 267.0
TLS3_k127_733328_2 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000008597 156.0
TLS3_k127_733328_3 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.0000000000000000000000000000000001073 147.0
TLS3_k127_733328_4 Trm112p-like protein K09791 - - 0.00000000000000000000653 94.0
TLS3_k127_733328_5 Carboxypeptidase regulatory-like domain - - - 0.00000000000000007666 94.0
TLS3_k127_733328_6 Domain of unknown function (DUF4388) - - - 0.00000001796 64.0
TLS3_k127_7345509_0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 7.594e-200 629.0
TLS3_k127_7345509_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 538.0
TLS3_k127_7345509_2 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000008039 206.0
TLS3_k127_7345509_3 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000007526 178.0
TLS3_k127_7345509_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000003228 153.0
TLS3_k127_7345509_5 Permease, YjgP YjgQ family K11720 - - 0.00000000000000003056 95.0
TLS3_k127_7345509_6 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00002456 57.0
TLS3_k127_7380980_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 346.0
TLS3_k127_7380980_1 involved in biosynthesis of extracellular polysaccharides - - - 0.000000000000000000000000000000000000000000000000001377 184.0
TLS3_k127_7380980_2 RNA recognition motif - - - 0.000000000000000428 80.0
TLS3_k127_7381502_0 tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 439.0
TLS3_k127_7381502_1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K03429 - 2.4.1.315 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 421.0
TLS3_k127_7381502_2 - - - - 0.00000000000000000000000000000000000000000000005506 175.0
TLS3_k127_7381502_3 alpha-ribazole phosphatase activity K01834 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009628,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036293,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.11 0.00000000000000003094 90.0
TLS3_k127_7400875_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 321.0
TLS3_k127_7400875_1 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001371 274.0
TLS3_k127_7400875_2 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000001069 223.0
TLS3_k127_7400875_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000002482 188.0
TLS3_k127_7400875_4 diguanylate cyclase - - - 0.000000000000000000000000000000000004252 149.0
TLS3_k127_7400875_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.00000000000000000000000003018 112.0
TLS3_k127_7429040_0 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000002095 269.0
TLS3_k127_7429040_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000001671 261.0
TLS3_k127_7444961_0 DEAD DEAH box helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003039 261.0
TLS3_k127_7444961_1 DEAD DEAH box helicase - - - 0.0000000000000000000000000000000000000000001948 175.0
TLS3_k127_7444961_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000000000000000002493 108.0
TLS3_k127_7451561_0 Urocanase Rossmann-like domain K01712 - 4.2.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 561.0
TLS3_k127_7451561_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000003292 263.0
TLS3_k127_7451561_2 esterase - - - 0.000000000000000000000000000000000000000006394 166.0
TLS3_k127_7454001_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000948 277.0
TLS3_k127_7454001_1 RNA polymerase, sigma-24 subunit, ECF subfamily K02405 - - 0.0000000000000000000000000000000000000000000000000000000001017 209.0
TLS3_k127_7454001_2 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000003585 203.0
TLS3_k127_7466730_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 463.0
TLS3_k127_7466730_1 DinB family - - - 0.000000000000000000000000000000000000000001502 164.0
TLS3_k127_7466730_2 - - - - 0.00000000000000000000000000001359 123.0
TLS3_k127_7466730_3 metallopeptidase activity - - - 0.00000000000000000000000002955 122.0
TLS3_k127_7475028_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 297.0
TLS3_k127_7475028_1 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001041 258.0
TLS3_k127_7475028_2 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000007469 204.0
TLS3_k127_7475028_3 heme a metabolic process K02259,K03110 - - 0.0000000000000000000000000000000000000000008555 169.0
TLS3_k127_7475028_4 Cytochrome c - - - 0.000000000000000000000000000000000000007852 150.0
TLS3_k127_750306_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 402.0
TLS3_k127_7515476_0 TIGRFAM Polyketide-type polyunsaturated fatty acid synthase, PfaA K15314 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002304 253.0
TLS3_k127_7515476_1 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.000000000000000000000000000000000000000000000000000000007422 209.0
TLS3_k127_7515476_2 Thioesterase-like superfamily K15315 - - 0.00000000000000000000000000000000000000000000000000000004459 199.0
TLS3_k127_7560704_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 309.0
TLS3_k127_7560704_1 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000007397 261.0
TLS3_k127_7560704_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.000000000000000000000001316 106.0
TLS3_k127_7566617_0 AMP-binding enzyme - - - 0.0 1615.0
TLS3_k127_7566617_1 Non-ribosomal peptide synthetase modules and related - - - 0.00000000000000000000000000000000000000002531 157.0
TLS3_k127_756940_0 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 374.0
TLS3_k127_756940_1 O-Antigen ligase K02847 - - 0.0000000000000000000000000000000000000006775 166.0
TLS3_k127_756940_2 O-methyltransferase activity - - - 0.000001755 60.0
TLS3_k127_76145_0 transcriptional regulator K03655 - 3.6.4.12 0.00000000000000000000000000000045 138.0
TLS3_k127_76145_1 von Willebrand factor, type A - - - 0.000000000000000000000004627 106.0
TLS3_k127_76145_2 - K01992 - - 0.0000008859 61.0
TLS3_k127_7655431_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372,K02567 - - 3.945e-284 891.0
TLS3_k127_7655431_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001244 234.0
TLS3_k127_7655431_2 nitrite transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000816 181.0
TLS3_k127_7672314_0 PFAM SNARE associated Golgi protein K03975 - - 0.00000000000000000000002184 104.0
TLS3_k127_7672314_1 PFAM CBS domain K03699 - - 0.00000000002151 64.0
TLS3_k127_7672314_2 Belongs to the universal stress protein A family - - - 0.0000001232 63.0
TLS3_k127_7693650_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.243e-255 805.0
TLS3_k127_7693650_1 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000003793 111.0
TLS3_k127_7704566_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001833 284.0
TLS3_k127_7704566_1 Methyltransferase domain - - - 0.00000000000000000000001246 101.0
TLS3_k127_7704772_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 527.0
TLS3_k127_7704772_1 M61 glycyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009306 331.0
TLS3_k127_7704772_2 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008203 280.0
TLS3_k127_7704772_3 lipid kinase, YegS Rv2252 BmrU family - - - 0.000000000000000000000000000000000000000000000001869 185.0
TLS3_k127_7728508_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 414.0
TLS3_k127_7728508_1 metallopeptidase activity K06212,K06402 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031224,GO:0031226,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 394.0
TLS3_k127_7728508_2 DoxX - - - 0.0000000000000000000000000000000000000000000000000000000000003327 214.0
TLS3_k127_7728508_3 - - - - 0.00000000000000000000000000000000000005352 149.0
TLS3_k127_7728508_4 PLD-like domain K06131 - - 0.00000000000000000000000001103 112.0
TLS3_k127_7746012_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000003655 243.0
TLS3_k127_7748165_0 Aldehyde oxidase and xanthine dehydrogenase a b hammerhead K03520,K11177 - 1.17.1.4,1.2.5.3 0.0 1270.0
TLS3_k127_7748165_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 355.0
TLS3_k127_7748165_2 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001102 259.0
TLS3_k127_7748375_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 474.0
TLS3_k127_7748375_1 von Willebrand factor, type A - - - 0.000000000007357 77.0
TLS3_k127_7759892_0 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003065 262.0
TLS3_k127_7759892_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000002864 181.0
TLS3_k127_7759892_2 metallopeptidase activity - - - 0.00000000000000000000000000000000000006508 153.0
TLS3_k127_7759892_3 - - - - 0.00000000000000000000000000000000007972 143.0
TLS3_k127_7759892_4 TonB dependent receptor K16087 - - 0.0003157 46.0
TLS3_k127_7765409_0 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 422.0
TLS3_k127_7765409_1 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 398.0
TLS3_k127_7765409_2 polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 306.0
TLS3_k127_7765409_3 Yip1 domain - - - 0.00000005612 64.0
TLS3_k127_7772207_0 D-aminopeptidase K16203 - - 0.0000000000000000000000000000000000000000000000000000000000002322 217.0
TLS3_k127_7772207_1 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000002691 201.0
TLS3_k127_7772207_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000001009 53.0
TLS3_k127_7772207_3 Rhodanese-like domain K01069 - 3.1.2.6 0.0000002278 55.0
TLS3_k127_7772207_4 Helix-turn-helix XRE-family like proteins - - - 0.00005518 49.0
TLS3_k127_7776557_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 471.0
TLS3_k127_7776557_2 - - - - 0.0000000000000000000000000000000000000000000000000000000006451 204.0
TLS3_k127_7776557_3 - - - - 0.0000007324 60.0
TLS3_k127_7776560_0 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000007249 235.0
TLS3_k127_7776560_1 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000000001808 168.0
TLS3_k127_7776560_2 Histidine kinase-like ATPase domain - - - 0.000000000000000000000000000001931 130.0
TLS3_k127_7776560_3 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000001772 54.0
TLS3_k127_7778681_0 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 402.0
TLS3_k127_7778681_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001782 273.0
TLS3_k127_7778681_2 PFAM Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.0000000000000000001779 94.0
TLS3_k127_7781593_0 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 351.0
TLS3_k127_7781593_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000009072 221.0
TLS3_k127_7781593_2 Carboxypeptidase regulatory-like domain - - - 0.0002075 48.0
TLS3_k127_779737_0 PFAM Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000101 281.0
TLS3_k127_779737_1 chemotaxis protein K03407 - 2.7.13.3 0.000000000000000000000000001457 123.0
TLS3_k127_7798295_0 phosphorelay signal transduction system K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 415.0
TLS3_k127_7798295_1 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 330.0
TLS3_k127_7798295_2 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 319.0
TLS3_k127_7803235_0 Condensation domain - - - 4.426e-202 646.0
TLS3_k127_7803329_0 amino acid - - - 2.128e-255 803.0
TLS3_k127_7803329_1 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000002536 190.0
TLS3_k127_7803329_2 Probable zinc-ribbon domain - - - 0.0000000000000000000000000003337 117.0
TLS3_k127_7803329_3 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000001853 112.0
TLS3_k127_7815360_0 Carboxypeptidase regulatory-like domain - - - 4.947e-251 795.0
TLS3_k127_7815360_1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 289.0
TLS3_k127_7821204_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 542.0
TLS3_k127_7821204_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 533.0
TLS3_k127_7821204_10 OsmC-like protein K06889,K07397 - - 0.000000000000000000000000000000000000000003263 158.0
TLS3_k127_7821204_11 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.0000000000000000000000000000003361 124.0
TLS3_k127_7821204_12 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000001039 124.0
TLS3_k127_7821204_13 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000004137 109.0
TLS3_k127_7821204_14 Regulatory protein - - - 0.0000000000000000000000001064 111.0
TLS3_k127_7821204_15 - - - - 0.000000000000000004445 91.0
TLS3_k127_7821204_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 505.0
TLS3_k127_7821204_3 Cys/Met metabolism PLP-dependent enzyme K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 486.0
TLS3_k127_7821204_4 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 488.0
TLS3_k127_7821204_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 338.0
TLS3_k127_7821204_6 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 329.0
TLS3_k127_7821204_7 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008463 330.0
TLS3_k127_7821204_8 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946,K07123 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000002259 239.0
TLS3_k127_7821204_9 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004799 226.0
TLS3_k127_7823595_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1056.0
TLS3_k127_7823595_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 316.0
TLS3_k127_7823595_2 Peptidase M14, carboxypeptidase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006868 268.0
TLS3_k127_7823595_3 GAF domain K08968 - 1.8.4.14 0.000000000000000000000000000000000000000000000000000000005596 204.0
TLS3_k127_7823595_4 Major Facilitator Superfamily - - - 0.000000000000008132 77.0
TLS3_k127_7838199_0 AAA ATPase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 449.0
TLS3_k127_7838199_1 TAP-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 370.0
TLS3_k127_7838199_2 - - - - 0.000000000000000000000000000000000000000000002182 173.0
TLS3_k127_7842734_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 404.0
TLS3_k127_7842734_1 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 387.0
TLS3_k127_7842734_2 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007542 302.0
TLS3_k127_7842734_3 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00000000000000000000006871 99.0
TLS3_k127_7858632_0 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003097 284.0
TLS3_k127_7860178_0 Domain of unknown function (DUF5117) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 529.0
TLS3_k127_7860178_1 protein kinase activity - - - 0.0000000000000000000000000000000000001648 144.0
TLS3_k127_7898947_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 366.0
TLS3_k127_7898947_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 336.0
TLS3_k127_7898947_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008168 318.0
TLS3_k127_7898947_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000002129 110.0
TLS3_k127_7898947_4 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000001135 56.0
TLS3_k127_7903027_0 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 542.0
TLS3_k127_7903027_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000004421 185.0
TLS3_k127_7903027_2 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.0000000000000000000000000001387 119.0
TLS3_k127_7903027_3 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000001195 98.0
TLS3_k127_7904090_0 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009538 387.0
TLS3_k127_7904090_1 Metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000006871 197.0
TLS3_k127_7914374_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007203 372.0
TLS3_k127_7919335_0 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 344.0
TLS3_k127_7919335_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 302.0
TLS3_k127_7919335_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004282 282.0
TLS3_k127_7919335_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000001175 223.0
TLS3_k127_7919335_4 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000008949 177.0
TLS3_k127_7919335_5 Participates in transcription elongation, termination and antitermination - - - 0.000000000000000000000000000000000000000000002517 174.0
TLS3_k127_7919335_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000002801 113.0
TLS3_k127_7931690_0 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009015 544.0
TLS3_k127_7931690_1 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001452 280.0
TLS3_k127_7931690_2 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002351 254.0
TLS3_k127_7931690_3 Belongs to the Fur family K09825 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000004543 126.0
TLS3_k127_7958142_0 HEAT repeats - - - 0.00000000000000000000000000000005674 142.0
TLS3_k127_7958142_1 oxidoreductase activity - - - 0.00000000000000000000000000006084 121.0
TLS3_k127_7958142_2 Armadillo/beta-catenin-like repeats - - - 0.000000000001154 81.0
TLS3_k127_7966234_0 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 455.0
TLS3_k127_7966234_1 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 408.0
TLS3_k127_7966234_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 350.0
TLS3_k127_7966234_3 Protein of unknown function (DUF1059) - - - 0.00000000000000000001123 94.0
TLS3_k127_7970060_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.767e-217 687.0
TLS3_k127_7970060_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000001773 253.0
TLS3_k127_7970060_2 Cytidylyltransferase K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000076 224.0
TLS3_k127_7970060_3 hyperosmotic response - - - 0.0000000000008283 71.0
TLS3_k127_7970060_4 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.000003394 49.0
TLS3_k127_7977569_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.829e-222 707.0
TLS3_k127_7978_0 glucose sorbosone K00117,K21430 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 398.0
TLS3_k127_7978_1 Response regulator receiver - - - 0.00000000000000000000003807 105.0
TLS3_k127_7978_2 PFAM sodium hydrogen exchanger K03455 - - 0.0000893 47.0
TLS3_k127_7980932_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 6.559e-286 901.0
TLS3_k127_7980932_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001119 237.0
TLS3_k127_7980932_2 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000002936 113.0
TLS3_k127_7980932_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000002109 96.0
TLS3_k127_7980932_4 Tetratricopeptide repeat - - - 0.00000000000000003006 94.0
TLS3_k127_7980932_5 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000001021 57.0
TLS3_k127_7991916_0 Serine threonine protein kinase involved in cell cycle control - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 380.0
TLS3_k127_7991916_1 transmembrane transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 334.0
TLS3_k127_7991916_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000714 225.0
TLS3_k127_7991916_3 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000006379 218.0
TLS3_k127_7991916_4 Protein of unknown function (DUF3037) - - - 0.0000000000000000000000000000000000000000000001169 171.0
TLS3_k127_7991916_5 - - - - 0.0000000000000000000000000000000000000004259 155.0
TLS3_k127_7991916_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000006379 136.0
TLS3_k127_7991916_7 Hemerythrin hhe cation binding - - - 0.000000000000000000000002013 111.0
TLS3_k127_7991916_8 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000002539 93.0
TLS3_k127_7991916_9 Putative addiction module component - - - 0.0002488 47.0
TLS3_k127_8005317_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001067 269.0
TLS3_k127_8005317_1 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000002812 169.0
TLS3_k127_8005317_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000001403 134.0
TLS3_k127_8020905_0 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 585.0
TLS3_k127_8020905_1 Glycosyl hydrolase family 92 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 328.0
TLS3_k127_8048395_0 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.00000000000000000000000000000006808 130.0
TLS3_k127_8048395_1 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 0.00000000007206 76.0
TLS3_k127_8076945_0 - - - - 0.00000000000000000000000000000000000000000000000000000168 201.0
TLS3_k127_8076945_1 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000005385 153.0
TLS3_k127_8076945_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000006173 145.0
TLS3_k127_8076945_3 Pfam:N_methyl_2 - - - 0.0000000000000000001984 94.0
TLS3_k127_8076945_4 ABC-type multidrug transport system ATPase K01990 - - 0.000000000000001145 78.0
TLS3_k127_8076945_5 Tellurite resistance protein TehB K03183 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.163,2.1.1.201 0.00000000000008501 81.0
TLS3_k127_8076945_6 response to antibiotic - - - 0.0000004094 57.0
TLS3_k127_8154685_0 Phosphate acyltransferases K00655,K01897 - 2.3.1.51,6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 505.0
TLS3_k127_8154685_1 Domain of unknown function (DUF374) K09778 - - 0.000000009352 64.0
TLS3_k127_8157157_0 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 383.0
TLS3_k127_8157157_1 heat shock protein binding - - - 0.0000004204 61.0
TLS3_k127_8157157_2 12 heme-binding sites - - - 0.000001241 60.0
TLS3_k127_8162439_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 394.0
TLS3_k127_8162439_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 0.00000000000000000000002276 100.0
TLS3_k127_8218804_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 430.0
TLS3_k127_8218804_1 Ribonuclease, Rne Rng family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 334.0
TLS3_k127_8226766_0 hydrolase, family 3 K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 424.0
TLS3_k127_8226766_1 Putative glucoamylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 427.0
TLS3_k127_8230670_0 oxidoreductase activity, acting on diphenols and related substances as donors - - - 0.0000000000000000000001213 102.0
TLS3_k127_8230670_1 Class III cytochrome C family - - - 0.0000754 52.0
TLS3_k127_8230670_2 Redoxin - - - 0.0002404 51.0
TLS3_k127_8240106_0 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000001424 231.0
TLS3_k127_8240106_1 3D domain - - - 0.0000000000000000001704 95.0
TLS3_k127_8240106_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000006865 89.0
TLS3_k127_8255676_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000694 260.0
TLS3_k127_8255676_1 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000001109 220.0
TLS3_k127_8255676_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000001064 171.0
TLS3_k127_8286020_0 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 336.0
TLS3_k127_8286020_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000311 188.0
TLS3_k127_8286020_11 Protein of unknown function (DUF3616) - - - 0.00004123 55.0
TLS3_k127_8286020_12 Subtilase family - - - 0.0002511 49.0
TLS3_k127_8286020_2 Fic/DOC family - - - 0.00000000000000000000000000000000000000001248 160.0
TLS3_k127_8286020_3 - - - - 0.0000000000000000000000000000000000009125 158.0
TLS3_k127_8286020_4 Subtilase family - - - 0.000000000000000000000000000000000002186 147.0
TLS3_k127_8286020_5 Subtilase family - - - 0.00000000000000000000000000000000008082 155.0
TLS3_k127_8286020_6 Carboxypeptidase K01298,K08781 - 3.4.17.1,3.4.17.15 0.00000000000000000000000000001548 133.0
TLS3_k127_8286020_7 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000005854 107.0
TLS3_k127_8286020_9 Subtilase family - - - 0.0000000001042 70.0
TLS3_k127_8304225_0 Aconitase C-terminal domain K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 328.0
TLS3_k127_8304225_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003198 251.0
TLS3_k127_8304225_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000589 195.0
TLS3_k127_8304225_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000007439 185.0
TLS3_k127_8304225_4 - - - - 0.000000008289 62.0
TLS3_k127_8331006_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 1.024e-289 912.0
TLS3_k127_8350467_0 Belongs to the proline racemase family K01777 - 5.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008135 431.0
TLS3_k127_8350467_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000004325 115.0
TLS3_k127_835996_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 465.0
TLS3_k127_835996_1 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000005434 245.0
TLS3_k127_835996_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000004935 167.0
TLS3_k127_8364612_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 578.0
TLS3_k127_8364612_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 378.0
TLS3_k127_8364612_2 beta-fructofuranosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 344.0
TLS3_k127_8364612_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008209 339.0
TLS3_k127_8364612_4 Small Multidrug Resistance protein - - - 0.000000000000000000000000000000000000005588 148.0
TLS3_k127_842927_0 penicillin-binding protein K05364 - - 0.000000000000000000000000000000000000000001829 176.0
TLS3_k127_842927_1 ABC transporter K01990,K21397 - - 0.00000000008885 70.0
TLS3_k127_8450060_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000001223 226.0
TLS3_k127_8450060_1 Trypsin K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 0.000629 51.0
TLS3_k127_8489431_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 585.0
TLS3_k127_8489431_1 DNA-templated transcription, initiation K02405 - - 0.000000000000000000000000000001722 123.0
TLS3_k127_8507716_0 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000006289 164.0
TLS3_k127_8555231_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 5.747e-200 634.0
TLS3_k127_865790_0 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 370.0
TLS3_k127_865790_1 helix_turn_helix gluconate operon transcriptional repressor K07978 - - 0.000000000000000000000000000000000000000000000000000000000000000000003388 245.0
TLS3_k127_865790_2 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000003646 115.0
TLS3_k127_865790_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000002521 63.0
TLS3_k127_88705_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 510.0
TLS3_k127_88705_1 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000005013 184.0
TLS3_k127_88705_2 COG1253 Hemolysins and related - - - 0.000000000000000000000000971 108.0
TLS3_k127_88705_3 - - - - 0.0000893 47.0
TLS3_k127_890962_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 419.0
TLS3_k127_890962_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 344.0
TLS3_k127_890962_2 phosphoserine phosphatase activity K07315,K16928 - 3.1.3.3 0.00000000000000000000357 98.0
TLS3_k127_892550_0 oxoglutarate dehydrogenase (succinyl-transferring) activity K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 308.0
TLS3_k127_892550_1 PFAM Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000305 241.0
TLS3_k127_896777_0 synthase - - - 0.0000000000000000000000000000000000000000000000000000000000001397 220.0
TLS3_k127_896777_1 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000003257 71.0
TLS3_k127_89718_0 Protease prsW family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 300.0
TLS3_k127_89718_1 Oxidoreductase activity. It is involved in the biological process described with metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 288.0
TLS3_k127_89718_2 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.0000000000000000000000000000000000000000000000000007824 193.0
TLS3_k127_89718_3 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000004527 121.0
TLS3_k127_898121_0 PQQ-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000001113 224.0
TLS3_k127_898121_1 PFAM Forkhead-associated protein - - - 0.00000000000000000000008102 105.0
TLS3_k127_898121_2 RDD family - - - 0.0000001407 60.0
TLS3_k127_907847_0 Capsular exopolysaccharide family K16554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001426 259.0
TLS3_k127_907847_1 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000002355 84.0
TLS3_k127_910675_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.888e-230 721.0
TLS3_k127_910675_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000001901 205.0
TLS3_k127_910675_2 RNA recognition motif - - - 0.0000000000000000000000000000000003443 136.0
TLS3_k127_910675_3 cAMP biosynthetic process K08884,K12132 - 2.7.11.1 0.0000000000000000000003692 97.0
TLS3_k127_913297_0 Vitamin B12 dependent methionine synthase, activation domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 1.521e-238 747.0
TLS3_k127_91712_0 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008863 438.0
TLS3_k127_91712_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 359.0
TLS3_k127_91712_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000002359 95.0
TLS3_k127_925524_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 1.627e-194 619.0
TLS3_k127_925524_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 439.0
TLS3_k127_925524_2 Ferredoxin - - - 0.00000000000000000000000000003356 120.0
TLS3_k127_931489_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 406.0
TLS3_k127_931489_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000179 76.0
TLS3_k127_931489_2 heat shock protein binding K03686,K05516 - - 0.00000000001291 74.0
TLS3_k127_93625_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 530.0
TLS3_k127_93625_1 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 341.0
TLS3_k127_93625_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 307.0
TLS3_k127_93625_3 UDP binding domain K00066 - 1.1.1.132 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 295.0
TLS3_k127_93625_4 rRNA (adenine-N6,N6-)-dimethyltransferase activity K02528,K20444 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000004832 195.0
TLS3_k127_93625_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0004 53.0
TLS3_k127_936254_0 Elongation factor G, domain IV K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 612.0
TLS3_k127_936254_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 374.0
TLS3_k127_936254_2 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000001059 213.0
TLS3_k127_936254_3 - - - - 0.000000000000000000000001823 112.0
TLS3_k127_949268_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 340.0
TLS3_k127_95280_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000006485 229.0
TLS3_k127_95280_1 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000007778 113.0
TLS3_k127_95280_2 PFAM single-stranded nucleic acid binding R3H domain protein K06346 - - 0.0000000000000000001424 94.0
TLS3_k127_95280_3 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000002909 70.0
TLS3_k127_95280_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000001226 64.0
TLS3_k127_956754_0 dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 405.0
TLS3_k127_956754_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 297.0
TLS3_k127_956754_2 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000005505 143.0
TLS3_k127_958092_0 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000004179 179.0
TLS3_k127_958092_1 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000002042 162.0
TLS3_k127_958092_2 Nucleotidyl transferase - - - 0.0000000000000000000000000000003408 128.0
TLS3_k127_958092_3 PLD-like domain - - - 0.0008791 47.0
TLS3_k127_958106_0 pyrroloquinoline quinone binding - - - 4.598e-207 658.0
TLS3_k127_958106_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 567.0
TLS3_k127_958106_2 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 445.0
TLS3_k127_958106_3 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 357.0
TLS3_k127_958106_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003836 250.0
TLS3_k127_958106_5 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000000000000001888 184.0
TLS3_k127_958106_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000000001165 139.0
TLS3_k127_958106_7 - - - - 0.0000000000000000000000000000002053 128.0
TLS3_k127_96197_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 416.0
TLS3_k127_96197_1 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 393.0
TLS3_k127_96197_2 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001439 269.0
TLS3_k127_96197_3 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000004574 168.0
TLS3_k127_96197_4 oxidoreductase activity - - - 0.00000000006455 74.0
TLS3_k127_965300_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 340.0
TLS3_k127_965300_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000001174 100.0
TLS3_k127_96997_0 PFAM Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 321.0
TLS3_k127_96997_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000001499 64.0
TLS3_k127_977104_0 cellulose binding - - - 0.0 1169.0
TLS3_k127_981484_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 367.0
TLS3_k127_981484_1 Subtilase family K14645 GO:0005575,GO:0005576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 354.0
TLS3_k127_981484_10 domain, Protein - - - 0.00008835 48.0
TLS3_k127_981484_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000003675 161.0
TLS3_k127_981484_3 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000002132 158.0
TLS3_k127_981484_4 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000000000000000000008742 141.0
TLS3_k127_981484_5 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000000000003096 131.0
TLS3_k127_981484_6 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000000000001054 121.0
TLS3_k127_981484_7 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000007225 104.0
TLS3_k127_981484_8 cheY-homologous receiver domain K11443 - - 0.000000000000000000003713 98.0
TLS3_k127_981484_9 Tetratricopeptide repeat - - - 0.0000000000001353 84.0
TLS3_k127_982649_0 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 355.0
TLS3_k127_982649_1 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001632 233.0
TLS3_k127_982649_2 Transport permease protein K01992 - - 0.0000000000000000000004465 97.0
TLS3_k127_987750_0 Phytanoyl-CoA dioxygenase (PhyH) K00477 - 1.14.11.18 0.000000000000000000000000000000000000000000000000000000007123 206.0
TLS3_k127_987750_1 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000006924 159.0
TLS3_k127_987750_2 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000000000001812 153.0