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Overview

ID MAG04047
Name TLS3_bin.24
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Actinomycetota
Class Thermoleophilia
Order Gaiellales
Family Gaiellaceae
Genus JAICNY01
Species JAICNY01 sp025930955
Assembly information
Completeness (%) 65.58
Contamination (%) 1.13
GC content (%) 73.0
N50 (bp) 6,591
Genome size (bp) 2,065,101

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2092

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_100720_0 Flavin containing amine oxidoreductase - - - 1.606e-228 716.0
TLS3_k127_100720_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 392.0
TLS3_k127_100720_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000001562 214.0
TLS3_k127_1027918_0 DNA methylase K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 338.0
TLS3_k127_1027918_1 helix_turn_helix, Lux Regulon K07696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001596 273.0
TLS3_k127_1027918_10 - - - - 0.0002535 46.0
TLS3_k127_1027918_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008203 280.0
TLS3_k127_1027918_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000008497 229.0
TLS3_k127_1027918_4 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000003598 172.0
TLS3_k127_1027918_5 cyclic nucleotide binding K10914 - - 0.0000000000000000001106 98.0
TLS3_k127_1027918_6 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000008375 69.0
TLS3_k127_1027918_7 - - - - 0.0000000001219 64.0
TLS3_k127_1027918_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000004017 66.0
TLS3_k127_1027918_9 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00006245 56.0
TLS3_k127_1040278_0 Rhodanese-like domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 367.0
TLS3_k127_1040278_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 306.0
TLS3_k127_1040278_2 Amidinotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003081 274.0
TLS3_k127_1040278_3 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000003568 104.0
TLS3_k127_1040278_4 Cytochrome oxidase assembly protein K02259 - - 0.00001303 55.0
TLS3_k127_1043744_0 Sodium:sulfate symporter transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 518.0
TLS3_k127_1043744_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 498.0
TLS3_k127_1043744_2 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002575 255.0
TLS3_k127_1043744_3 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000009023 210.0
TLS3_k127_1043744_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000003323 156.0
TLS3_k127_1043744_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000009579 158.0
TLS3_k127_1043744_6 Uncharacterized conserved protein (COG2071) K09166 - - 0.0000000004038 68.0
TLS3_k127_1056933_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 415.0
TLS3_k127_1056933_1 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006881 391.0
TLS3_k127_1056933_2 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 393.0
TLS3_k127_1056933_3 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 331.0
TLS3_k127_1056933_4 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 310.0
TLS3_k127_1056933_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001006 258.0
TLS3_k127_1056933_6 Family 5 K15580 - - 0.0000000000000000000000000000000000000000000000000000006847 220.0
TLS3_k127_1056933_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000005567 194.0
TLS3_k127_1056933_8 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.3.14 0.0004981 44.0
TLS3_k127_1056966_0 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 412.0
TLS3_k127_1056966_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 388.0
TLS3_k127_1056966_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003907 280.0
TLS3_k127_1056966_3 - - - - 0.00000000000000000000000000000009496 136.0
TLS3_k127_1056966_4 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.00000000001504 78.0
TLS3_k127_1057441_0 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 325.0
TLS3_k127_1057441_1 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000002348 265.0
TLS3_k127_1057441_2 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000006255 135.0
TLS3_k127_1075142_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 486.0
TLS3_k127_1075142_1 Protein of unknown function (DUF1360) - - - 0.00000000000000000000000000000000000006691 150.0
TLS3_k127_1075142_2 AhpC/TSA family - - - 0.000000000000000000000000000000000002155 157.0
TLS3_k127_1075142_3 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000000000000001521 85.0
TLS3_k127_1075142_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000126 89.0
TLS3_k127_1077063_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 359.0
TLS3_k127_1077063_1 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.00000000000000000000000000005186 121.0
TLS3_k127_1077063_2 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000007535 109.0
TLS3_k127_1077063_3 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000002549 94.0
TLS3_k127_1077063_4 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000004351 60.0
TLS3_k127_1081154_0 Trehalose synthase K05343 GO:0000023,GO:0000271,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016160,GO:0016161,GO:0016787,GO:0016798,GO:0016853,GO:0016866,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046872,GO:0047471,GO:0055114,GO:0071704,GO:0071944,GO:1901576 3.2.1.1,5.4.99.16 3.769e-272 848.0
TLS3_k127_1081154_1 protein, probably involved in trehalose biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 501.0
TLS3_k127_1081154_2 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000002503 267.0
TLS3_k127_1081475_0 Sigma-70 factor, region 1.2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 365.0
TLS3_k127_1081475_1 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 313.0
TLS3_k127_1081475_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000004118 260.0
TLS3_k127_1081475_3 cellulase activity - - - 0.00000000000000000000000000000000000000000000006655 195.0
TLS3_k127_1084541_0 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000006944 184.0
TLS3_k127_1084541_1 ATPase associated with various cellular activities K03924 - - 0.0000000000000000000000001802 108.0
TLS3_k127_1084541_2 PFAM bifunctional deaminase-reductase domain protein - - - 0.0000000000000000007532 89.0
TLS3_k127_1084541_3 RibD C-terminal domain - - - 0.00000005565 55.0
TLS3_k127_1084541_4 Esterase-like activity of phytase K03929 - - 0.00009515 50.0
TLS3_k127_1107781_0 OB-fold nucleic acid binding domain K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000008158 238.0
TLS3_k127_1107781_1 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000531 239.0
TLS3_k127_1107781_2 Belongs to the CinA family - - - 0.000000000000000000003545 98.0
TLS3_k127_1107781_3 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000003897 79.0
TLS3_k127_1121231_0 Belongs to the aldehyde dehydrogenase family K22187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 458.0
TLS3_k127_1121231_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000435 261.0
TLS3_k127_1121231_2 - - - - 0.0000000000000000000000000000002476 140.0
TLS3_k127_1121231_3 Histidine kinase - - - 0.000000000000000000000000007113 128.0
TLS3_k127_1153590_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1433.0
TLS3_k127_1165169_0 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000001611 121.0
TLS3_k127_1165169_1 Domain of unknown function (DUF4349) - - - 0.00000000000000000000001108 112.0
TLS3_k127_1165169_2 Thioesterase K07107 - - 0.000000000000002618 85.0
TLS3_k127_1169257_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001817 287.0
TLS3_k127_1169257_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003582 275.0
TLS3_k127_1169257_2 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000008046 212.0
TLS3_k127_1169257_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000001676 207.0
TLS3_k127_1169257_4 LVIVD repeat - - - 0.00000000000000000000000000000000002634 149.0
TLS3_k127_1195002_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 346.0
TLS3_k127_1195002_1 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 310.0
TLS3_k127_1195002_2 Methyltransferase small domain - - - 0.00000000000000000000000002036 121.0
TLS3_k127_1195002_3 LemA family K03744 - - 0.000000000000000000000000105 108.0
TLS3_k127_1201219_0 homoserine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 589.0
TLS3_k127_1201219_1 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 373.0
TLS3_k127_1201219_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 340.0
TLS3_k127_1201219_3 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000005065 249.0
TLS3_k127_1201219_4 Nucleotidyl transferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000008661 149.0
TLS3_k127_1201219_5 Glycosyl transferase, family 2 K07011 - - 0.0000000000000000000000000000000000002409 161.0
TLS3_k127_1201219_6 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000007075 151.0
TLS3_k127_1201219_7 PFAM PHP domain protein K01104 - 3.1.3.48 0.00000000000000000000000005912 124.0
TLS3_k127_1201219_8 O-Antigen ligase - - - 0.00000000000001426 87.0
TLS3_k127_1202988_0 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 596.0
TLS3_k127_1202988_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008714 311.0
TLS3_k127_1202988_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000007961 258.0
TLS3_k127_1202988_3 Arginase family K01476 - 3.5.3.1 0.00000000000000000000000000004174 126.0
TLS3_k127_1202988_4 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000001523 103.0
TLS3_k127_1208885_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 573.0
TLS3_k127_1208885_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 382.0
TLS3_k127_1208885_10 (twin-arginine translocation) pathway signal - - - 0.00000000000000000000000000000000000000000996 170.0
TLS3_k127_1208885_11 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.00000000000000000000000000002017 134.0
TLS3_k127_1208885_12 Gram-negative-bacterium-type cell wall biogenesis - - - 0.0000000000000000000001406 113.0
TLS3_k127_1208885_13 - - - - 0.0000000000000001416 85.0
TLS3_k127_1208885_14 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000003113 83.0
TLS3_k127_1208885_15 AAA domain - - - 0.0000000000002116 79.0
TLS3_k127_1208885_16 - - - - 0.00000002877 61.0
TLS3_k127_1208885_17 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000004006 64.0
TLS3_k127_1208885_18 IrrE N-terminal-like domain K07110 GO:0001666,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0036293,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070482,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0004646 47.0
TLS3_k127_1208885_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 343.0
TLS3_k127_1208885_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 340.0
TLS3_k127_1208885_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000002547 246.0
TLS3_k127_1208885_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000001905 243.0
TLS3_k127_1208885_6 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001187 235.0
TLS3_k127_1208885_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000004153 193.0
TLS3_k127_1208885_8 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000001424 186.0
TLS3_k127_1208885_9 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000007642 186.0
TLS3_k127_1220416_0 Malate synthase K01638 - 2.3.3.9 1.765e-212 678.0
TLS3_k127_1220416_1 Isocitrate lyase K01637 - 4.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 317.0
TLS3_k127_1220416_2 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 298.0
TLS3_k127_1220416_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000005755 206.0
TLS3_k127_1220416_4 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.0000000000000000000000000000000000000628 147.0
TLS3_k127_1220416_5 Dienelactone hydrolase - - - 0.000002384 55.0
TLS3_k127_1256008_0 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001076 242.0
TLS3_k127_1256008_1 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000001157 211.0
TLS3_k127_1256008_2 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000006697 148.0
TLS3_k127_1256008_3 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000002241 124.0
TLS3_k127_1256008_4 - - - - 0.0000000000000000000002012 101.0
TLS3_k127_1256008_5 Chorismate mutase K03856,K04092,K04093,K04516,K13853 - 2.5.1.54,5.4.99.5 0.00000000000000001709 85.0
TLS3_k127_1256965_0 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 606.0
TLS3_k127_1256965_1 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 486.0
TLS3_k127_1256965_2 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 433.0
TLS3_k127_1256965_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000003537 228.0
TLS3_k127_1256965_4 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000004808 132.0
TLS3_k127_1256965_5 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000001477 107.0
TLS3_k127_1256965_6 response to antibiotic K02066,K04749,K07122 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716 - 0.0000000000000000000004325 98.0
TLS3_k127_1257190_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 412.0
TLS3_k127_1257190_1 AAA ATPase central domain protein - GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019725,GO:0030003,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033212,GO:0033214,GO:0033554,GO:0040007,GO:0042592,GO:0042594,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051704,GO:0051716,GO:0055065,GO:0055069,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071944,GO:0072507,GO:0098771 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 391.0
TLS3_k127_1257190_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000004823 220.0
TLS3_k127_1257190_3 Transcriptional regulator - - - 0.0000000000000000009278 101.0
TLS3_k127_1263367_0 PFAM UDP-glucose GDP-mannose dehydrogenase K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 454.0
TLS3_k127_1263367_1 Glycosyl transferase, family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 301.0
TLS3_k127_1263367_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000285 201.0
TLS3_k127_1263367_3 Protein of unknown function (DUF354) K09726 - - 0.000000000000000000000000000000000000000000000000216 181.0
TLS3_k127_1263367_4 NAD-dependent epimerase dehydratase K01784,K17947 - 5.1.3.2,5.1.3.25 0.000000000001173 78.0
TLS3_k127_1263367_5 epimerase K02377 - 1.1.1.271 0.00000000002339 76.0
TLS3_k127_1275805_0 NlpC/P60 family K21473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000167 257.0
TLS3_k127_1275805_1 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000001825 190.0
TLS3_k127_1275805_2 Domain of unknown function (DUF4111) - - - 0.000000000000000000000000000000000000000000005881 177.0
TLS3_k127_1275805_3 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000006013 113.0
TLS3_k127_1289827_0 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000471 199.0
TLS3_k127_1289827_1 protein N-acetylglucosaminyltransferase activity - - - 0.00000000000000000000000000000000000000000000465 181.0
TLS3_k127_1289827_2 Glycosyl transferase 4-like - - - 0.000000000000000000000000000178 133.0
TLS3_k127_1289827_3 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000009232 126.0
TLS3_k127_1289827_4 polysaccharide deacetylase - - - 0.000000000000001997 82.0
TLS3_k127_1296529_0 Response regulator receiver K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000001524 234.0
TLS3_k127_1296529_1 Protein of unknown function (DUF3152) - - - 0.0000000000000000000000000000000000000000000000219 186.0
TLS3_k127_1296529_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07652 - 2.7.13.3 0.0000000000000000000000000000000000000000005939 171.0
TLS3_k127_1296529_3 - K10716 - - 0.000000000000000000000000000002928 135.0
TLS3_k127_1296529_4 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000004626 91.0
TLS3_k127_1296529_5 - - - - 0.0000000000000000644 88.0
TLS3_k127_1296529_6 Domain of unknown function (DUF305) - - - 0.00000000000003941 74.0
TLS3_k127_1296529_7 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000001069 74.0
TLS3_k127_1306394_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 5.457e-195 629.0
TLS3_k127_1306394_1 Extracellular solute-binding protein, family 5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 437.0
TLS3_k127_1306394_2 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 415.0
TLS3_k127_1306394_3 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 357.0
TLS3_k127_1306394_4 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 335.0
TLS3_k127_1306394_5 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 308.0
TLS3_k127_1306394_6 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002403 258.0
TLS3_k127_1306394_7 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000003727 224.0
TLS3_k127_1306394_8 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000004126 207.0
TLS3_k127_1306394_9 NAD dependent epimerase/dehydratase family K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000911 174.0
TLS3_k127_1320852_0 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000002925 218.0
TLS3_k127_1320852_1 lysR family - - - 0.0000000000000000000000000000000000000000000000000000004912 209.0
TLS3_k127_1320852_2 InterPro IPR014922 - - - 0.00000000000000000000000000000000000000000000000007375 190.0
TLS3_k127_1320852_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000007447 122.0
TLS3_k127_1320852_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000015 115.0
TLS3_k127_1320852_5 Membrane - - - 0.000000000000003214 79.0
TLS3_k127_1429915_0 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 320.0
TLS3_k127_1429915_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 304.0
TLS3_k127_1429915_2 PFAM Glucose Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002427 275.0
TLS3_k127_1429915_3 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.00000000000000000000000000000000000000012 171.0
TLS3_k127_1450382_0 ATP-grasp - - - 0.000000000000000000000000000000000000000000000007267 187.0
TLS3_k127_1450382_1 Belongs to the eIF-2B alpha beta delta subunits family K03680 - - 0.000000000000000000000000155 118.0
TLS3_k127_1450382_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000001538 109.0
TLS3_k127_1450382_3 PQQ-like domain - - - 0.000000000000000007756 91.0
TLS3_k127_1474561_1 LVIVD repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004239 268.0
TLS3_k127_168572_0 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009361 473.0
TLS3_k127_168572_1 Integral membrane protein TerC family K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 361.0
TLS3_k127_168572_2 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001483 284.0
TLS3_k127_168572_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001715 253.0
TLS3_k127_168572_4 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000001334 177.0
TLS3_k127_168572_5 Cbs domain - - - 0.0000000000000000000000000000000000000000000005886 178.0
TLS3_k127_168572_6 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000009268 97.0
TLS3_k127_168572_7 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000001044 67.0
TLS3_k127_1719525_0 Histidine kinase K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 344.0
TLS3_k127_1719525_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001515 286.0
TLS3_k127_1719525_2 Two component transcriptional regulator, winged helix family K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004596 280.0
TLS3_k127_1719525_3 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006919 269.0
TLS3_k127_1719525_4 Domain of unknown function (DUF202) K00389 - - 0.0000000000000001711 92.0
TLS3_k127_1719525_5 - - - - 0.000000000000001313 89.0
TLS3_k127_172058_0 COG COG0210 Superfamily I DNA and RNA helicases DNA replication recombination and repair K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 367.0
TLS3_k127_172058_1 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000001435 149.0
TLS3_k127_1724087_0 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005859 273.0
TLS3_k127_1724087_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000003153 182.0
TLS3_k127_1724087_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000006153 171.0
TLS3_k127_1724087_3 PFAM Ferric reductase domain protein transmembrane component domain K17247 - - 0.000000000000000000000002914 117.0
TLS3_k127_1758550_0 Cys met metabolism pyridoxal-phosphate-dependent K01739 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 454.0
TLS3_k127_1758550_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01697 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 4.2.1.22 0.00000000000002307 75.0
TLS3_k127_1758550_2 PFAM Glycosyl transferase, group 1 - - - 0.000000001123 61.0
TLS3_k127_1760210_0 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 313.0
TLS3_k127_1760210_1 Belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.00000000000000000000000000000000000000000000000000000000000349 214.0
TLS3_k127_1760210_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.00000000000000000000000000000000000000000000000000006131 195.0
TLS3_k127_1760210_3 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000001996 187.0
TLS3_k127_1760210_4 PFAM Peptidase family M23 K21472 - - 0.0000000000000000000000194 117.0
TLS3_k127_1760210_5 response to heat K07090 - - 0.0000000000004107 81.0
TLS3_k127_1760210_6 Sulfite exporter TauE/SafE K07090 - - 0.000000001061 64.0
TLS3_k127_1768623_0 xanthine dehydrogenase, a b hammerhead - - - 2.864e-222 705.0
TLS3_k127_1768623_1 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 305.0
TLS3_k127_1768623_2 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 292.0
TLS3_k127_1768623_3 Enoyl-CoA hydratase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000001702 244.0
TLS3_k127_1768623_4 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000004346 241.0
TLS3_k127_1768623_5 TIGRFAM phenylacetate-CoA oxygenase, PaaJ subunit K02612 - - 0.000000000000000000000000000000000000000000000001974 188.0
TLS3_k127_1768623_6 PFAM phenylacetic acid catabolic family protein K02611 - 1.14.13.149 0.00000000000000000000000000000000000000000000003366 177.0
TLS3_k127_1768623_7 phenylacetate catabolic process K02610 - - 0.00000000000000009603 82.0
TLS3_k127_1768623_8 Putative inner membrane exporter, YdcZ K09936 - - 0.00000000000001667 82.0
TLS3_k127_1768623_9 sequence-specific DNA binding - - - 0.00000000000004535 83.0
TLS3_k127_1772133_0 Belongs to the SEDS family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009487 394.0
TLS3_k127_1772133_1 Penicillin binding protein transpeptidase domain K05364 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 345.0
TLS3_k127_1772133_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 332.0
TLS3_k127_1772133_3 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000002237 235.0
TLS3_k127_1777602_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 467.0
TLS3_k127_1777602_1 Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP K01939 GO:0000166,GO:0001882,GO:0001883,GO:0002376,GO:0003674,GO:0003824,GO:0004019,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006520,GO:0006531,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042301,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.4.4 0.00001661 47.0
TLS3_k127_178625_0 PFAM Endonuclease Exonuclease phosphatase K07004 - - 2.174e-211 704.0
TLS3_k127_178625_1 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 531.0
TLS3_k127_178625_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 478.0
TLS3_k127_178625_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 374.0
TLS3_k127_178625_4 Belongs to the CinA family K03742,K03743 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 312.0
TLS3_k127_178625_5 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000009317 174.0
TLS3_k127_178625_6 phosphatase K01083,K07004 - 3.1.3.8 0.0000000000000000000000007762 123.0
TLS3_k127_178625_7 Domain of unknown function (DUF4115) - - - 0.00000000000000000000002016 110.0
TLS3_k127_178625_8 LigT like Phosphoesterase K01975 - 3.1.4.58 0.000000000006341 78.0
TLS3_k127_178625_9 Modulates RecA activity K03565 - - 0.0001053 53.0
TLS3_k127_179196_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000009494 256.0
TLS3_k127_179196_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 GO:0000166,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259,GO:0036094,GO:0040007,GO:0042083,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050797,GO:0070402,GO:0097159,GO:1901265,GO:1901363 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000007241 212.0
TLS3_k127_179196_2 PFAM short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.00000000000000000000000000000000000008313 152.0
TLS3_k127_179196_3 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000001168 148.0
TLS3_k127_179196_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000002983 132.0
TLS3_k127_179196_5 Anti-sigma-K factor rskA - - - 0.0004374 52.0
TLS3_k127_1805797_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 321.0
TLS3_k127_1805797_1 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000002264 237.0
TLS3_k127_1805797_2 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000000000000000001767 158.0
TLS3_k127_1805797_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000009692 147.0
TLS3_k127_1805797_4 Domain of unknown function (DUF2520) - - - 0.000000000000000000000000000001237 126.0
TLS3_k127_1805797_5 Belongs to the peptidase S8 family - - - 0.000000000000000000000000006648 128.0
TLS3_k127_1805797_6 Glycoprotease family K14742 GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.00000000000000000000001817 108.0
TLS3_k127_1805797_7 TIGRFAM regulatory protein, FmdB - - - 0.000000003032 63.0
TLS3_k127_1808180_0 Squalene--hopene cyclase K06045 - 4.2.1.129,5.4.99.17 6.752e-206 659.0
TLS3_k127_1808180_1 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 335.0
TLS3_k127_1808180_2 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000001919 231.0
TLS3_k127_1813853_0 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 407.0
TLS3_k127_1813853_1 e3 binding domain K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 353.0
TLS3_k127_1813853_2 Dehydrogenase E1 component K00161,K00166,K11381,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 326.0
TLS3_k127_1813853_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 295.0
TLS3_k127_1813853_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004261 293.0
TLS3_k127_1813853_5 ASCH domain - - - 0.0000000000000000000000000000000000004286 147.0
TLS3_k127_1813853_6 NUDIX domain - - - 0.00000000000000000000000000000000001071 142.0
TLS3_k127_1813853_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000003316 123.0
TLS3_k127_183405_0 possibly catalyzes the transport of a undeterminated metal cation with the hydrolyse of ATP catalytic activity ATP H(2)O undeterminated metal cation(in) ADP phosphate undeterminated metal cation(out) K01537 - 3.6.3.8 1.742e-220 713.0
TLS3_k127_183405_1 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 536.0
TLS3_k127_183405_2 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 495.0
TLS3_k127_183405_3 Type III restriction enzyme, res subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 372.0
TLS3_k127_183405_4 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009213 329.0
TLS3_k127_183405_5 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000001123 220.0
TLS3_k127_183405_6 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000001185 186.0
TLS3_k127_183405_7 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000003911 170.0
TLS3_k127_183405_8 isochorismatase - - - 0.00000000000000000000000000004584 128.0
TLS3_k127_183405_9 Histidine kinase-like ATPase domain - - - 0.000000000747 64.0
TLS3_k127_1871458_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 8.433e-243 760.0
TLS3_k127_1871458_1 Rhodanese Homology Domain - - - 3.585e-203 657.0
TLS3_k127_1871458_10 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000001184 86.0
TLS3_k127_1871458_13 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00006128 51.0
TLS3_k127_1871458_2 Molybdate transporter of MFS superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 379.0
TLS3_k127_1871458_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 329.0
TLS3_k127_1871458_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000001826 241.0
TLS3_k127_1871458_5 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000004639 232.0
TLS3_k127_1871458_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000003198 217.0
TLS3_k127_1871458_7 Ferritin-like domain K22336 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000002214 202.0
TLS3_k127_1871458_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000002191 154.0
TLS3_k127_1871458_9 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000002849 133.0
TLS3_k127_1872654_0 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002045 264.0
TLS3_k127_1872654_1 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000001104 250.0
TLS3_k127_1872654_2 COG1520 FOG WD40-like repeat - - - 0.0000000000000000000000000000000001854 145.0
TLS3_k127_1872654_3 ATP-grasp - - - 0.0000000000000000000000002033 114.0
TLS3_k127_1872654_4 PFAM O-Antigen ligase - - - 0.0001113 55.0
TLS3_k127_1872654_5 Glycosyltransferase family 87 - - - 0.0006922 52.0
TLS3_k127_1891952_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 439.0
TLS3_k127_1891952_1 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000007666 259.0
TLS3_k127_1891952_2 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000002793 177.0
TLS3_k127_1891952_3 Protein of unknown function (DUF1272) K09984 - - 0.000000000000003123 76.0
TLS3_k127_1891952_4 Tetratricopeptide repeat - - - 0.000321 52.0
TLS3_k127_1906239_0 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 356.0
TLS3_k127_1906239_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 342.0
TLS3_k127_1906239_10 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) - - - 0.0007376 51.0
TLS3_k127_1906239_2 Catalyzes the conversion of dihydroorotate to orotate K00254,K17828 - 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000008303 235.0
TLS3_k127_1906239_3 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000004755 197.0
TLS3_k127_1906239_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000001054 175.0
TLS3_k127_1906239_5 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K02823 - - 0.0000000000000000000000000000000000000009207 156.0
TLS3_k127_1906239_6 - - - - 0.000000000000000000000000000000000003713 140.0
TLS3_k127_1906239_7 Protein of unknown function DUF58 - - - 0.00000000000000000000005667 115.0
TLS3_k127_1906239_8 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000002339 105.0
TLS3_k127_1906239_9 Transfers the fatty acyl group on membrane lipoproteins K03820 GO:0000030,GO:0003674,GO:0003824,GO:0004582,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070085,GO:0071704,GO:0071944,GO:0075136,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000189 90.0
TLS3_k127_1914824_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K01281 - 3.4.14.11 3.66e-223 711.0
TLS3_k127_1914824_1 Endonuclease NucS K07503 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 320.0
TLS3_k127_1914824_2 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.0000000000000009978 77.0
TLS3_k127_1922394_0 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008459 461.0
TLS3_k127_1922394_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 382.0
TLS3_k127_1922394_2 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000001331 188.0
TLS3_k127_1925687_0 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 473.0
TLS3_k127_1925687_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000002622 260.0
TLS3_k127_1925687_2 geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000000006043 208.0
TLS3_k127_1925687_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000006077 117.0
TLS3_k127_1925687_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00001538 55.0
TLS3_k127_1928295_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 371.0
TLS3_k127_1928295_1 AzlC protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004965 234.0
TLS3_k127_1928295_10 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.000000000000000000000000349 122.0
TLS3_k127_1928295_12 ompA family - - - 0.00000000348 70.0
TLS3_k127_1928295_2 PFAM N-acetylglucosaminyl phosphatidylinositol deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000001655 224.0
TLS3_k127_1928295_3 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000000000247 214.0
TLS3_k127_1928295_4 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000000000000000000000000000000000000000007102 208.0
TLS3_k127_1928295_5 Pfam SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000002432 189.0
TLS3_k127_1928295_6 ATPases associated with a variety of cellular activities K09817 - - 0.00000000000000000000000000000000000000000000001207 193.0
TLS3_k127_1928295_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000004086 185.0
TLS3_k127_1928295_8 D-glucuronyl C5-epimerase C-terminus - - - 0.00000000000000000000000000000007021 143.0
TLS3_k127_1928295_9 Ferric uptake regulator family K03711 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000006469 125.0
TLS3_k127_193726_0 Aldehyde dehydrogenase family K00137 - 1.2.1.19 2.317e-200 644.0
TLS3_k127_193726_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 448.0
TLS3_k127_193726_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 421.0
TLS3_k127_193726_3 helix_turn_helix ASNC type K03718 - - 0.00000000000000000000000000000000000000000000002821 181.0
TLS3_k127_193726_4 PFAM extracellular solute-binding protein family 1 K11069 - - 0.0000000000000000000000000000000000002867 158.0
TLS3_k127_1939484_0 Iron-sulfur cluster-binding protein K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 458.0
TLS3_k127_1939484_1 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 310.0
TLS3_k127_1939484_2 aminodeoxychorismate synthase K01665,K03342 - 2.6.1.85,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000573 223.0
TLS3_k127_1939484_3 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000298 175.0
TLS3_k127_1939484_4 Amino-transferase class IV K02619 - 4.1.3.38 0.0000000000000000000000000000000000000000000005397 183.0
TLS3_k127_1939484_5 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000008372 151.0
TLS3_k127_1939484_6 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000001035 138.0
TLS3_k127_1939484_7 Pfam:DUF162 K00782 - - 0.000000000000004882 89.0
TLS3_k127_1939484_8 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000001173 76.0
TLS3_k127_1939484_9 protein, YerC YecD - - - 0.0000006129 61.0
TLS3_k127_1944581_0 Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 414.0
TLS3_k127_1944581_1 NlpC/P60 family - - - 0.0000000000000000000000000000000000000000000000007666 188.0
TLS3_k127_1944581_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.5 0.000000000000000000000004343 111.0
TLS3_k127_1944581_3 PAS domain - - - 0.000000000000000000002916 106.0
TLS3_k127_1944581_4 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00004163 55.0
TLS3_k127_1945905_0 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000007999 232.0
TLS3_k127_1945905_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000009333 74.0
TLS3_k127_1945905_3 - - - - 0.000000001611 61.0
TLS3_k127_1955356_0 ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008545 265.0
TLS3_k127_1955356_1 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000004216 236.0
TLS3_k127_1955356_2 - - - - 0.000000000000000000000000000000000000000000003514 172.0
TLS3_k127_1955356_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000437 184.0
TLS3_k127_1955356_4 Beta-lactamase K01286 - 3.4.16.4 0.000000000000000000003866 108.0
TLS3_k127_1967592_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 594.0
TLS3_k127_1967592_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 360.0
TLS3_k127_1967592_2 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.00000000000000000000000000000000000005058 164.0
TLS3_k127_1967592_3 Glucose-6-phosphate dehydrogenase subunit - - - 0.00000000000000000000000000000004201 136.0
TLS3_k127_1973878_0 protein-(glutamine-N5) methyltransferase activity K00543,K16130,K18896,K18897,K21515 - 2.1.1.156,2.1.1.157,2.1.1.209,2.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000003118 242.0
TLS3_k127_1973878_1 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000001125 222.0
TLS3_k127_1973878_2 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K02479 - - 0.000000000000000000000000000000000000124 159.0
TLS3_k127_1973878_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000001995 150.0
TLS3_k127_1973878_4 Ribonuclease B OB domain K03704 - - 0.0000000000000000000000006362 105.0
TLS3_k127_1973878_5 Parallel beta-helix repeats - - - 0.0000000000001792 83.0
TLS3_k127_1973878_6 - - - - 0.0002708 49.0
TLS3_k127_1976643_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 436.0
TLS3_k127_1976643_1 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000001926 218.0
TLS3_k127_1978335_0 dipeptidyl-peptidase K01281 - 3.4.14.11 1.306e-213 677.0
TLS3_k127_1978335_1 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs K05825,K18907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 396.0
TLS3_k127_1978335_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000005421 232.0
TLS3_k127_1978335_3 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.00000000000000000000003997 103.0
TLS3_k127_1980594_0 NAD-glutamate dehydrogenase K15371 - 1.4.1.2 5.167e-235 751.0
TLS3_k127_1980594_1 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000001441 228.0
TLS3_k127_1980594_2 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000001081 202.0
TLS3_k127_1980594_3 NADP oxidoreductase coenzyme F420-dependent - - - 0.00000000000000000000000000000000003146 142.0
TLS3_k127_1980594_4 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.00000000000000000001603 94.0
TLS3_k127_1986795_0 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000002026 204.0
TLS3_k127_1986795_1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000002178 169.0
TLS3_k127_1986795_2 PFAM Peptidase S24 S26A S26B, conserved region K03100 - 3.4.21.89 0.00000000000000000000000000000000000000001241 169.0
TLS3_k127_199294_0 protein methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 446.0
TLS3_k127_199294_1 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 306.0
TLS3_k127_199294_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000001714 251.0
TLS3_k127_199294_3 Protein of unknown function (DUF354) K09726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000178 256.0
TLS3_k127_199294_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109,K02113 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000001106 107.0
TLS3_k127_199294_5 ATP synthase B/B' CF(0) K02109 - - 0.000000000000000000009419 98.0
TLS3_k127_199294_6 ATP synthase subunit C K02110 - - 0.0000000000000000008824 99.0
TLS3_k127_199294_7 Protein conserved in bacteria K09914 - - 0.000000000137 74.0
TLS3_k127_199294_8 - - - - 0.0000001766 56.0
TLS3_k127_199294_9 - - - - 0.0007687 49.0
TLS3_k127_1994029_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.383e-232 745.0
TLS3_k127_1994029_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000008313 227.0
TLS3_k127_1994029_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001634 202.0
TLS3_k127_1994029_3 Diguanylate cyclase - - - 0.00000000000000000000000002016 123.0
TLS3_k127_2001683_0 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000000000000000000000000000000002573 224.0
TLS3_k127_2001683_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000001305 178.0
TLS3_k127_2001683_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 2.7.7.60 0.00000000000000000000000000000000000001152 159.0
TLS3_k127_2001683_3 DNA integrity scanning protein DisA K07067 - 2.7.7.85 0.000000000000000000000000000115 118.0
TLS3_k127_2001683_4 endonuclease III K03575 - - 0.000000000000000000000000002746 115.0
TLS3_k127_2004648_0 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005863 276.0
TLS3_k127_2004648_1 Aminotransferase class-III K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000001969 252.0
TLS3_k127_2004648_2 3-beta hydroxysteroid dehydrogenase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000002593 171.0
TLS3_k127_2004648_3 SUF system FeS assembly protein, NifU family K04488 - - 0.0000000000000000000000000000000003509 139.0
TLS3_k127_2004648_4 O-methyltransferase - - - 0.0000000000000000000000000000001154 136.0
TLS3_k127_2004648_5 Rieske 2Fe-2S iron-sulphur domain K05710 - - 0.0000000000000000000000000000004612 124.0
TLS3_k127_2004648_6 - - - - 0.00000000000000000002618 94.0
TLS3_k127_2015454_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 414.0
TLS3_k127_2015454_1 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000001603 186.0
TLS3_k127_2015454_2 translation release factor activity - - - 0.00000000000000000000009989 110.0
TLS3_k127_2015454_3 AraC-like ligand binding domain - - - 0.00000000000000000005727 93.0
TLS3_k127_2025353_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 591.0
TLS3_k127_2025353_1 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 486.0
TLS3_k127_2025353_10 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000002139 136.0
TLS3_k127_2025353_11 PspC domain K03973 - - 0.0000000000000006538 79.0
TLS3_k127_2025353_12 cell division protein FtsQ K03589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.0000000615 64.0
TLS3_k127_2025353_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 472.0
TLS3_k127_2025353_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 449.0
TLS3_k127_2025353_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 372.0
TLS3_k127_2025353_5 Mur ligase family, catalytic domain K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001726 273.0
TLS3_k127_2025353_6 Protein of unknown function, DUF480 - - - 0.000000000000000000000000000000000000000000000000000000000000000000396 237.0
TLS3_k127_2025353_7 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000505 201.0
TLS3_k127_2025353_8 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000003244 194.0
TLS3_k127_2025353_9 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000005487 158.0
TLS3_k127_2031429_0 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 397.0
TLS3_k127_2031429_1 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 348.0
TLS3_k127_2031429_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000107 268.0
TLS3_k127_2031429_3 Copper resistance protein D K14166 - - 0.00000000000000000000000000000000000000000000000000000001029 219.0
TLS3_k127_2031429_4 Domain of unkown function (DUF1775) - - - 0.000000000000000000000000000000009942 136.0
TLS3_k127_2031429_5 LVIVD repeat - - - 0.00000000006946 76.0
TLS3_k127_2031429_6 ABC-2 family transporter protein - - - 0.00000008995 64.0
TLS3_k127_2057353_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.0 1194.0
TLS3_k127_2057353_1 xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 1.191e-300 940.0
TLS3_k127_2057353_10 carbon monoxide dehydrogenase subunit G K09386 - - 0.000000000000000000000000000000000003492 156.0
TLS3_k127_2057353_11 Peptidoglycan-binding domain 1 protein K01185,K17733 - 3.2.1.17 0.0000000000000000002402 98.0
TLS3_k127_2057353_2 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 381.0
TLS3_k127_2057353_3 von Willebrand factor, type A K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 327.0
TLS3_k127_2057353_4 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 336.0
TLS3_k127_2057353_5 PFAM molybdopterin dehydrogenase, FAD-binding K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 321.0
TLS3_k127_2057353_6 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 297.0
TLS3_k127_2057353_7 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000001467 245.0
TLS3_k127_2057353_8 COGs COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000049 238.0
TLS3_k127_2057353_9 YHS domain K07402 - - 0.000000000000000000000000000000000000000000000000001322 204.0
TLS3_k127_2114686_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 3.069e-207 657.0
TLS3_k127_2114686_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 596.0
TLS3_k127_2114686_10 competence protein - - - 0.0000000000000000000000001359 115.0
TLS3_k127_2114686_2 Methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008437 537.0
TLS3_k127_2114686_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 507.0
TLS3_k127_2114686_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 346.0
TLS3_k127_2114686_5 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000306 293.0
TLS3_k127_2114686_6 Cell envelope-related transcriptional attenuator domain - - - 0.00000000000000000000000000000000000000000006063 183.0
TLS3_k127_2114686_7 Sigma 54 modulation protein / S30EA ribosomal protein K05808 - - 0.0000000000000000000000000000000000000001737 156.0
TLS3_k127_2114686_8 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000001503 171.0
TLS3_k127_2114686_9 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000001676 141.0
TLS3_k127_2123089_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000005061 228.0
TLS3_k127_2123089_1 NLP P60 protein K21471 - - 0.00000000000000000000000000000000000004547 156.0
TLS3_k127_2123089_2 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000000000001289 106.0
TLS3_k127_2123089_3 3D domain K02424 - - 0.000000000000000000379 103.0
TLS3_k127_21322_0 PFAM NADH Ubiquinone plastoquinone (complex I) K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 463.0
TLS3_k127_21322_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 362.0
TLS3_k127_21322_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008975 320.0
TLS3_k127_21322_3 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 297.0
TLS3_k127_21322_4 oxidoreductase - - - 0.000000000000000000000000000008253 134.0
TLS3_k127_21322_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000005214 109.0
TLS3_k127_21322_6 cAMP-dependent protein kinase regulator activity K04739 GO:0000003,GO:0000166,GO:0000187,GO:0000226,GO:0000280,GO:0001704,GO:0001707,GO:0001932,GO:0001933,GO:0001934,GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0003006,GO:0003008,GO:0003014,GO:0003091,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0005886,GO:0005929,GO:0005952,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006469,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0007010,GO:0007015,GO:0007017,GO:0007049,GO:0007143,GO:0007154,GO:0007162,GO:0007163,GO:0007165,GO:0007267,GO:0007268,GO:0007274,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007308,GO:0007309,GO:0007369,GO:0007389,GO:0007498,GO:0007507,GO:0007591,GO:0007596,GO:0007599,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007635,GO:0008103,GO:0008150,GO:0008152,GO:0008283,GO:0008285,GO:0008306,GO:0008355,GO:0008603,GO:0009611,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009798,GO:0009887,GO:0009888,GO:0009889,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0009994,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010628,GO:0010639,GO:0010646,GO:0010647,GO:0010648,GO:0010721,GO:0010738,GO:0010927,GO:0010948,GO:0014706,GO:0014855,GO:0015630,GO:0016020,GO:0016043,GO:0016310,GO:0016325,GO:0017076,GO:0019207,GO:0019210,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0019932,GO:0019933,GO:0019935,GO:0019953,GO:0021700,GO:0022402,GO:0022407,GO:0022408,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030029,GO:0030036,GO:0030104,GO:0030154,GO:0030155,GO:0030234,GO:0030239,GO:0030291,GO:0030435,GO:0030551,GO:0030552,GO:0030554,GO:0030587,GO:0030951,GO:0030952,GO:0031032,GO:0031154,GO:0031156,GO:0031285,GO:0031288,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031399,GO:0031400,GO:0031401,GO:0031588,GO:0031594,GO:0031625,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032553,GO:0032555,GO:0032559,GO:0032870,GO:0032878,GO:0032944,GO:0032945,GO:0032989,GO:0032991,GO:0033002,GO:0033043,GO:0033673,GO:0033674,GO:0033762,GO:0034199,GO:0034236,GO:0035265,GO:0035556,GO:0036094,GO:0036211,GO:0040007,GO:0040020,GO:0042048,GO:0042060,GO:0042127,GO:0042129,GO:0042130,GO:0042221,GO:0042303,GO:0042325,GO:0042326,GO:0042327,GO:0042493,GO:0042592,GO:0042692,GO:0042802,GO:0042995,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043412,GO:0043434,GO:0043549,GO:0043900,GO:0043901,GO:0043934,GO:0043949,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044853,GO:0045121,GO:0045202,GO:0045214,GO:0045471,GO:0045595,GO:0045596,GO:0045786,GO:0045835,GO:0045859,GO:0045860,GO:0045936,GO:0045937,GO:0046006,GO:0046007,GO:0046677,GO:0048285,GO:0048332,GO:0048468,GO:0048469,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048520,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048598,GO:0048599,GO:0048609,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048856,GO:0048869,GO:0048871,GO:0048878,GO:0050670,GO:0050672,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050795,GO:0050817,GO:0050863,GO:0050865,GO:0050866,GO:0050868,GO:0050877,GO:0050878,GO:0050890,GO:0050891,GO:0050896,GO:0051018,GO:0051093,GO:0051128,GO:0051129,GO:0051146,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051249,GO:0051250,GO:0051252,GO:0051321,GO:0051338,GO:0051347,GO:0051348,GO:0051445,GO:0051447,GO:0051703,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051784,GO:0055001,GO:0055002,GO:0055017,GO:0060038,GO:0060255,GO:0060259,GO:0060281,GO:0060283,GO:0060284,GO:0060419,GO:0060537,GO:0061061,GO:0061695,GO:0061939,GO:0065007,GO:0065008,GO:0065009,GO:0070663,GO:0070664,GO:0070887,GO:0070925,GO:0071310,GO:0071375,GO:0071377,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071900,GO:0071901,GO:0071902,GO:0071944,GO:0072359,GO:0072375,GO:0080090,GO:0090036,GO:0090038,GO:0090702,GO:0097159,GO:0097305,GO:0097367,GO:0097435,GO:0097546,GO:0098589,GO:0098590,GO:0098772,GO:0098805,GO:0098857,GO:0098916,GO:0099120,GO:0099536,GO:0099537,GO:0120025,GO:0120038,GO:0140013,GO:1900193,GO:1900194,GO:1901265,GO:1901363,GO:1901564,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902494,GO:1902531,GO:1902532,GO:1902533,GO:1902911,GO:1903037,GO:1903038,GO:1903046,GO:1903429,GO:1903430,GO:1903506,GO:1903538,GO:1905879,GO:1905880,GO:1990234,GO:2000112,GO:2000114,GO:2000241,GO:2000242,GO:2000253,GO:2000479,GO:2000480,GO:2001141 - 0.00000009671 64.0
TLS3_k127_21322_7 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 - - - 0.0000004588 55.0
TLS3_k127_2163521_0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1341.0
TLS3_k127_2163521_1 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 559.0
TLS3_k127_2163521_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 411.0
TLS3_k127_2163521_3 50S ribosome-binding GTPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001357 294.0
TLS3_k127_2163521_4 cellular response to starvation - GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0050896,GO:0051716,GO:0071496 - 0.000000002693 62.0
TLS3_k127_2224480_0 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 453.0
TLS3_k127_2224480_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 342.0
TLS3_k127_2224480_2 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000009183 224.0
TLS3_k127_2224480_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000001079 187.0
TLS3_k127_2224480_4 Domain of Unknown Function (DUF326) - - - 0.000000000000000000000000000000000000000000000001153 179.0
TLS3_k127_2224480_5 glycosyl transferase family 1 - - - 0.00000000001915 74.0
TLS3_k127_2448793_0 Binding-protein-dependent transport systems inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 478.0
TLS3_k127_2448793_1 iron ion homeostasis K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 350.0
TLS3_k127_2448793_2 ABC-type spermidine putrescine transport systems, ATPase components K02010 - 3.6.3.30 0.00000000000000000000000000000001056 132.0
TLS3_k127_2459182_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 434.0
TLS3_k127_2459182_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768,K01769 - 4.6.1.1,4.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 326.0
TLS3_k127_2459182_2 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000001142 212.0
TLS3_k127_2459182_3 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000001297 180.0
TLS3_k127_2459182_5 Phosphoenolpyruvate phosphomutase - - - 0.00000005527 57.0
TLS3_k127_2459182_6 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000001235 51.0
TLS3_k127_2534090_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 568.0
TLS3_k127_2534090_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000001869 260.0
TLS3_k127_2534090_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000004208 180.0
TLS3_k127_2534090_3 Alkylmercury lyase - - - 0.000000000000000001923 98.0
TLS3_k127_2534090_4 Alkylmercury lyase - - - 0.00000000000234 69.0
TLS3_k127_2557722_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 440.0
TLS3_k127_2557722_1 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000297 196.0
TLS3_k127_2557722_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000001256 171.0
TLS3_k127_2557722_3 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000007207 102.0
TLS3_k127_2557722_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000002916 106.0
TLS3_k127_258079_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000009826 213.0
TLS3_k127_258079_1 Response regulator receiver K02479 - - 0.00000000000000000000000000000000000000000000000000003793 205.0
TLS3_k127_258079_2 Transglycosylase SLT domain - - - 0.00000000000000000000000003201 124.0
TLS3_k127_258079_3 PFAM TadE family protein - - - 0.00000000000000009043 86.0
TLS3_k127_258079_4 Peptidase A24A, prepilin type IV K02654 - 3.4.23.43 0.00000000000001269 85.0
TLS3_k127_2582089_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 386.0
TLS3_k127_2582089_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 351.0
TLS3_k127_2582089_2 binding-protein-dependent transport systems inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 328.0
TLS3_k127_2582089_3 Pfam Cation efflux - - - 0.00000000000000000000000000000000000000000000000000000000000000000001215 241.0
TLS3_k127_2582089_4 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000008284 185.0
TLS3_k127_2582089_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000006961 175.0
TLS3_k127_2582089_6 COG0226 ABC-type phosphate transport system, periplasmic component K02040 - - 0.0001134 46.0
TLS3_k127_2582333_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1087.0
TLS3_k127_2582333_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000005871 276.0
TLS3_k127_2582333_2 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000001532 210.0
TLS3_k127_2582333_3 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.00000000000000000000002162 101.0
TLS3_k127_2582333_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00003567 56.0
TLS3_k127_2594424_0 Aminotransferase class-III K01845 - 5.4.3.8 1.781e-237 740.0
TLS3_k127_2594424_1 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 368.0
TLS3_k127_2594424_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 380.0
TLS3_k127_2594424_3 Peptidase family S58 K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 312.0
TLS3_k127_2594424_4 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000001801 237.0
TLS3_k127_2594424_5 cellulase activity - - - 0.00000000000000000000000000000000000000000000001603 199.0
TLS3_k127_2594424_6 Type ii secretion system K12510 - - 0.0000000000000000000000000000000000001671 157.0
TLS3_k127_2594424_7 Type II secretion system (T2SS), protein F K12511 - - 0.0000000000000000000000000000000000006002 151.0
TLS3_k127_2594424_9 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000009219 104.0
TLS3_k127_2603151_0 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 327.0
TLS3_k127_2603151_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000003297 218.0
TLS3_k127_2603151_2 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000004493 181.0
TLS3_k127_2603151_3 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000002557 136.0
TLS3_k127_2603151_4 Transcriptional regulatory protein, C terminal K02483,K07658 - - 0.000000000000000000000000001457 123.0
TLS3_k127_2603151_5 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000008633 115.0
TLS3_k127_2603151_6 Conserved repeat domain - - - 0.0000006513 61.0
TLS3_k127_2618692_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000002692 160.0
TLS3_k127_2618692_1 Inositol monophosphatase family K01092,K05602 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008934,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016053,GO:0016137,GO:0016138,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052745,GO:0052803,GO:0052834,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659 3.1.3.15,3.1.3.25 0.0000000000000000000000000000000000000001101 164.0
TLS3_k127_2618692_2 Histidine biosynthesis bifunctional protein HisIE K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000001979 111.0
TLS3_k127_2618692_3 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.000000000000000000000001462 114.0
TLS3_k127_2618939_0 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 407.0
TLS3_k127_2618939_1 Formate dehydrogenase, beta subunit K00122 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 372.0
TLS3_k127_2618939_2 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 329.0
TLS3_k127_2618939_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000297 159.0
TLS3_k127_2618939_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000001057 156.0
TLS3_k127_2626332_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 428.0
TLS3_k127_2626332_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 363.0
TLS3_k127_2626332_2 domain protein K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 294.0
TLS3_k127_2626332_3 - - - - 0.0000000000000000002753 102.0
TLS3_k127_2626332_4 JAB/MPN domain - - - 0.0000001723 64.0
TLS3_k127_2627235_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.333e-241 759.0
TLS3_k127_2627235_1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 569.0
TLS3_k127_2627235_10 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000002103 204.0
TLS3_k127_2627235_11 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000001322 153.0
TLS3_k127_2627235_12 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000003863 133.0
TLS3_k127_2627235_13 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000003962 117.0
TLS3_k127_2627235_14 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000008212 110.0
TLS3_k127_2627235_15 type II secretion system protein E K02652 - - 0.000000000000007838 89.0
TLS3_k127_2627235_16 ThiS family - - - 0.0001151 53.0
TLS3_k127_2627235_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 321.0
TLS3_k127_2627235_3 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000916 289.0
TLS3_k127_2627235_4 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001439 282.0
TLS3_k127_2627235_5 Electron transfer flavoprotein domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003549 271.0
TLS3_k127_2627235_6 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003776 247.0
TLS3_k127_2627235_7 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000154 212.0
TLS3_k127_2627235_8 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000002233 224.0
TLS3_k127_2627235_9 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000001783 201.0
TLS3_k127_2627529_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001428 261.0
TLS3_k127_2627529_1 efflux transmembrane transporter activity - - - 0.00000000000005689 85.0
TLS3_k127_2627765_0 Cytochrome b K03887 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 303.0
TLS3_k127_2627765_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000005863 250.0
TLS3_k127_2627765_2 Belongs to the FPP GGPP synthase family - - - 0.0000000000000000000000000000000000000000000000000000000006402 211.0
TLS3_k127_2627765_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000001261 192.0
TLS3_k127_2627765_4 Cytochrome b subunit of the bc K03888 - - 0.00000000000000000000000000000000000000001462 163.0
TLS3_k127_2627765_5 Rieske 2Fe-2S - - - 0.0000000000000000000000002373 112.0
TLS3_k127_2631530_0 Transmembrane secretion effector K18215 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009219 361.0
TLS3_k127_2631530_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 340.0
TLS3_k127_2631530_2 Transmembrane secretion effector K18215 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 331.0
TLS3_k127_2631530_3 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000006602 113.0
TLS3_k127_2631543_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007792 493.0
TLS3_k127_2631543_1 Pyridoxal-phosphate dependent enzyme K01505,K05396 - 3.5.99.7,4.4.1.15 0.000000000000000000000000000000000000000000000006766 173.0
TLS3_k127_2631543_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000002481 177.0
TLS3_k127_2631543_3 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon K03709 - - 0.0000000000000000000000001285 123.0
TLS3_k127_2648387_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 316.0
TLS3_k127_2648387_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001376 293.0
TLS3_k127_2648387_10 PFAM DivIVA family protein K04074 - - 0.000000000000003199 82.0
TLS3_k127_2648387_11 YGGT family K02221 - - 0.0000000000106 68.0
TLS3_k127_2648387_2 PFAM Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002559 285.0
TLS3_k127_2648387_3 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 - - 0.000000000000000000000000000000000000000000000000000000003957 207.0
TLS3_k127_2648387_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000001564 191.0
TLS3_k127_2648387_5 Alanine racemase, N-terminal domain K06997 - - 0.00000000000000000000000000000000000000000000006029 182.0
TLS3_k127_2648387_6 PFAM peptidase M50 - - - 0.00000000000000000000000000000000000002599 163.0
TLS3_k127_2648387_7 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000002819 117.0
TLS3_k127_2648387_8 diguanylate cyclase - - - 0.0000000000000000000000007118 118.0
TLS3_k127_2648387_9 PFAM Prokaryotic dksA traR C4-type zinc finger - - - 0.0000000000000000006842 92.0
TLS3_k127_2651572_0 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 477.0
TLS3_k127_2651572_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 462.0
TLS3_k127_2651572_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 404.0
TLS3_k127_2651572_3 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002623 251.0
TLS3_k127_2656143_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 529.0
TLS3_k127_2656143_1 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 328.0
TLS3_k127_2656143_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 302.0
TLS3_k127_2656143_3 Belongs to the binding-protein-dependent transport system permease family K01997,K11956 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000219 284.0
TLS3_k127_2656143_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001266 293.0
TLS3_k127_2656143_5 ABC-type branched-chain amino acid transport systems ATPase component K01996,K11958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001518 272.0
TLS3_k127_2656143_6 Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.00000000000000000000000000000000000000001087 155.0
TLS3_k127_2663989_0 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002985 259.0
TLS3_k127_2663989_1 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000002852 203.0
TLS3_k127_2664959_0 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 561.0
TLS3_k127_2664959_1 cyclase dehydrase - - - 0.000000000000000000000000000000000000000000000000000000007849 204.0
TLS3_k127_2664959_2 lactoylglutathione lyase activity - - - 0.000000000000002317 84.0
TLS3_k127_2671566_0 COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 2.089e-252 796.0
TLS3_k127_2671566_1 COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 7.977e-228 722.0
TLS3_k127_2671566_10 Cobalamin synthesis protein cobW C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 374.0
TLS3_k127_2671566_11 protein involved in propionate catabolism - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 374.0
TLS3_k127_2671566_12 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 373.0
TLS3_k127_2671566_13 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 364.0
TLS3_k127_2671566_14 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 350.0
TLS3_k127_2671566_15 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 330.0
TLS3_k127_2671566_16 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 328.0
TLS3_k127_2671566_17 Acetamidase formamidase K01455 - 3.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 327.0
TLS3_k127_2671566_18 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K13995 - 3.5.1.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 334.0
TLS3_k127_2671566_19 DNA import into cell involved in transformation K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001791 268.0
TLS3_k127_2671566_2 Amidohydrolase family K01464 - 3.5.2.2 6.582e-225 722.0
TLS3_k127_2671566_20 Asparaginase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000005776 270.0
TLS3_k127_2671566_21 PFAM binding-protein-dependent transport systems inner membrane component K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001427 263.0
TLS3_k127_2671566_22 Carbon-nitrogen hydrolase K01501 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000006175 252.0
TLS3_k127_2671566_23 MaoC like domain K18290 - 4.2.1.56 0.00000000000000000000000000000000000000000000000000000000000000000001016 238.0
TLS3_k127_2671566_24 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000001953 218.0
TLS3_k127_2671566_25 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000003056 199.0
TLS3_k127_2671566_26 Isochorismatase family K13995 - 3.5.1.107 0.000000000000000000000000000000000000000000000003516 183.0
TLS3_k127_2671566_27 Thioesterase K07107 - - 0.00000000000000000000000000000000000000000000003346 171.0
TLS3_k127_2671566_28 transcriptional regulator - - - 0.000000000000000000000000000000000000000000009249 187.0
TLS3_k127_2671566_3 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 602.0
TLS3_k127_2671566_30 Thioredoxin - - - 0.0000000000000000000001988 104.0
TLS3_k127_2671566_31 Bacterial extracellular solute-binding protein K02055 - - 0.0000000006119 60.0
TLS3_k127_2671566_32 Putative regulatory protein - - - 0.00000005735 55.0
TLS3_k127_2671566_33 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00001767 57.0
TLS3_k127_2671566_34 His Kinase A (phosphoacceptor) domain - - - 0.0001281 50.0
TLS3_k127_2671566_4 TIGRFAM Amidase, hydantoinase carbamoylase K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 604.0
TLS3_k127_2671566_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 578.0
TLS3_k127_2671566_6 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 541.0
TLS3_k127_2671566_7 Ectoine utilization protein EutC K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 529.0
TLS3_k127_2671566_8 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 535.0
TLS3_k127_2671566_9 FAD linked oxidases, C-terminal domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009105 445.0
TLS3_k127_2682987_0 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005892 638.0
TLS3_k127_2682987_1 ATPases associated with a variety of cellular activities K02056,K06400 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 597.0
TLS3_k127_2682987_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 403.0
TLS3_k127_2682987_3 Basic membrane lipoprotein K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 330.0
TLS3_k127_2682987_4 Psort location Cytoplasmic, score 7.50 K01250 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 311.0
TLS3_k127_2682987_5 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000002621 128.0
TLS3_k127_2682987_6 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000002994 105.0
TLS3_k127_2696475_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 292.0
TLS3_k127_2696475_1 Segregation and condensation complex subunit ScpB K06024 - - 0.0000000000000000000000000000000000007318 153.0
TLS3_k127_2696475_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000001492 154.0
TLS3_k127_2696475_3 GYD domain - - - 0.000000000000000000791 89.0
TLS3_k127_2696475_4 - - - - 0.0006441 47.0
TLS3_k127_2697523_0 Clp domain protein K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 551.0
TLS3_k127_2697523_1 CoA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 377.0
TLS3_k127_2697523_2 6-phospho-beta-galactosidase activity - - - 0.000000000000000000000000000000003027 145.0
TLS3_k127_2697523_3 membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000000004329 89.0
TLS3_k127_2718901_0 Helix-hairpin-helix domain K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000005268 248.0
TLS3_k127_2718901_1 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000003612 108.0
TLS3_k127_2720050_0 Type II/IV secretion system protein K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 491.0
TLS3_k127_2720050_1 NUBPL iron-transfer P-loop NTPase K02282 - - 0.0000000000000000000000000000000000000000000009289 187.0
TLS3_k127_2720050_2 Type II secretion system (T2SS), protein F K12510 - - 0.000000002962 70.0
TLS3_k127_2720050_3 Pilus assembly protein K02279 - - 0.00000001131 65.0
TLS3_k127_2720050_4 TadE-like protein - - - 0.00000002506 61.0
TLS3_k127_2720050_5 Flp pilus assembly protein, pilin Flp K02651 - - 0.00002545 50.0
TLS3_k127_2720050_6 Putative Tad-like Flp pilus-assembly - - - 0.000603 53.0
TLS3_k127_2720196_0 protein involved in exopolysaccharide biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 652.0
TLS3_k127_2720196_1 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000095 586.0
TLS3_k127_2720196_10 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 329.0
TLS3_k127_2720196_11 Uncharacterised protein family (UPF0261) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 309.0
TLS3_k127_2720196_12 Periplasmic binding protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007165 289.0
TLS3_k127_2720196_13 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001662 251.0
TLS3_k127_2720196_14 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000001305 229.0
TLS3_k127_2720196_15 transcriptional regulator DeoR family K02081,K03436 - - 0.0000000000000000000000000000008962 131.0
TLS3_k127_2720196_16 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000002441 117.0
TLS3_k127_2720196_17 protein possibly involved in utilization of glycolate and propanediol - - - 0.000004319 59.0
TLS3_k127_2720196_2 AP endonuclease family 2 C terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 575.0
TLS3_k127_2720196_3 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 510.0
TLS3_k127_2720196_4 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 467.0
TLS3_k127_2720196_5 myo-inosose-2 dehydratase activity K01805 - 5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 425.0
TLS3_k127_2720196_6 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 409.0
TLS3_k127_2720196_7 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 368.0
TLS3_k127_2720196_8 ATPases associated with a variety of cellular activities K10545 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 347.0
TLS3_k127_2720196_9 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 350.0
TLS3_k127_2720652_0 Phosphorylase superfamily K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 346.0
TLS3_k127_2720652_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 324.0
TLS3_k127_2720652_2 Inorganic H+ pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000008478 230.0
TLS3_k127_2720652_3 Alpha beta hydrolase - - - 0.00000000000000000001933 101.0
TLS3_k127_2720652_4 - - - - 0.000000000001157 74.0
TLS3_k127_2741353_0 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 405.0
TLS3_k127_2741353_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 317.0
TLS3_k127_2741353_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000001058 227.0
TLS3_k127_2787667_0 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 496.0
TLS3_k127_2787667_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949 436.0
TLS3_k127_2787667_2 Belongs to the LDH MDH superfamily. LDH family K00016,K00024 - 1.1.1.27,1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001008 279.0
TLS3_k127_2802714_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 291.0
TLS3_k127_2802714_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003122 287.0
TLS3_k127_2802714_2 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000003069 245.0
TLS3_k127_2802714_3 - - - - 0.000000000000000000000000000000000000000000000000000000001017 211.0
TLS3_k127_2802714_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000001145 192.0
TLS3_k127_2802714_5 AsnC-type helix-turn-helix domain K05710 - - 0.000000000000000000000000000000000000000000000002062 182.0
TLS3_k127_2802714_6 serine threonine protein kinase - - - 0.000000000000000000008327 102.0
TLS3_k127_2802714_7 Sigma-70, region 4 - - - 0.00000000000000000003365 97.0
TLS3_k127_2802714_8 - - - - 0.00000000000004909 79.0
TLS3_k127_2815549_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 424.0
TLS3_k127_2815549_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 286.0
TLS3_k127_2815549_2 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000115 221.0
TLS3_k127_2815549_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000003413 148.0
TLS3_k127_2815549_4 cellulose binding - - - 0.00000000000001801 86.0
TLS3_k127_2815549_5 cellulose binding - - - 0.0000000000003779 80.0
TLS3_k127_282392_0 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002158 280.0
TLS3_k127_282392_1 NmrA-like family - - - 0.00000000000000000000000000004695 125.0
TLS3_k127_282392_2 CcmE - - - 0.00000000000000001312 88.0
TLS3_k127_282392_3 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.000000002838 69.0
TLS3_k127_282392_4 PFAM Xylose isomerase domain protein TIM barrel K01151 - 3.1.21.2 0.0004308 46.0
TLS3_k127_28246_0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 364.0
TLS3_k127_28246_1 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000006759 262.0
TLS3_k127_28246_2 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000001869 250.0
TLS3_k127_28246_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000001174 176.0
TLS3_k127_28246_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000001425 140.0
TLS3_k127_28246_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000001637 68.0
TLS3_k127_28246_6 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000003503 60.0
TLS3_k127_2835299_0 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 461.0
TLS3_k127_2835299_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 391.0
TLS3_k127_2835299_2 PFAM regulatory protein LuxR - - - 0.00000000000000000000000000000000000000000000000000000000008107 212.0
TLS3_k127_2835299_3 COG COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism General function prediction only - - - 0.00000000000000000000000000000000000002142 154.0
TLS3_k127_2835299_4 - - - - 0.000000776 55.0
TLS3_k127_28574_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 3.255e-263 830.0
TLS3_k127_28574_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 607.0
TLS3_k127_28574_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 558.0
TLS3_k127_28574_3 Alpha-glucan phosphorylase K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 495.0
TLS3_k127_28574_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K18357 - 1.2.1.58,1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000007965 256.0
TLS3_k127_2874385_0 Multicopper oxidase - - - 1.207e-202 639.0
TLS3_k127_2874385_1 phosphorelay signal transduction system K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 514.0
TLS3_k127_2874385_2 Glycosyl Transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 366.0
TLS3_k127_2874385_3 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000001263 206.0
TLS3_k127_2874385_4 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000001348 217.0
TLS3_k127_2874385_5 transcriptional regulator - - - 0.00000000000000000000000000003634 124.0
TLS3_k127_2874385_6 - - - - 0.000000005474 66.0
TLS3_k127_2874745_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 352.0
TLS3_k127_2874745_1 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000816 365.0
TLS3_k127_2874745_2 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000004129 227.0
TLS3_k127_2874745_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000004491 218.0
TLS3_k127_2904133_0 Thermophilic metalloprotease (M29) K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 395.0
TLS3_k127_2904133_1 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 368.0
TLS3_k127_2904133_2 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009087 364.0
TLS3_k127_2904133_3 Thermophilic metalloprotease (M29) K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000008322 222.0
TLS3_k127_2904133_4 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000008537 214.0
TLS3_k127_2904133_5 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000005501 210.0
TLS3_k127_2904133_6 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000136 160.0
TLS3_k127_2904133_7 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000234 158.0
TLS3_k127_2904133_8 Hypothetical methyltransferase - - - 0.000000000000000006294 94.0
TLS3_k127_2904133_9 LysM domain - - - 0.000000005688 62.0
TLS3_k127_2930205_0 phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 384.0
TLS3_k127_2930205_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 303.0
TLS3_k127_2930205_2 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000004616 99.0
TLS3_k127_2932969_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 556.0
TLS3_k127_2932969_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 417.0
TLS3_k127_2932969_2 MazG nucleotide pyrophosphohydrolase domain K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000002822 227.0
TLS3_k127_2932969_3 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K01802,K07533 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000002779 90.0
TLS3_k127_2932969_4 Protein of unknown function (DUF501) K09009 - - 0.000000001218 61.0
TLS3_k127_2932969_5 Septum formation initiator - - - 0.0000001196 57.0
TLS3_k127_2966269_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 509.0
TLS3_k127_2966269_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 344.0
TLS3_k127_2966269_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 338.0
TLS3_k127_2966269_3 LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 291.0
TLS3_k127_2978964_0 ABC transporter K06158 - - 1.732e-203 653.0
TLS3_k127_2978964_1 Belongs to the transketolase family K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000004714 259.0
TLS3_k127_3034642_0 Belongs to the bacterial solute-binding protein 9 family K09818,K11707 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 391.0
TLS3_k127_3034642_1 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000007736 224.0
TLS3_k127_3034642_2 Transglycosylase SLT domain - - - 0.0000000000000000000000002064 121.0
TLS3_k127_3034642_3 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000841 107.0
TLS3_k127_3034642_4 TIGRFAM Flp pilus assembly protein CpaB K02279 - - 0.00000000001048 72.0
TLS3_k127_3034642_5 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000004452 75.0
TLS3_k127_3034642_6 PFAM ABC transporter related K11710 - - 0.00000000008377 73.0
TLS3_k127_3034642_7 TadE-like protein - - - 0.00000006712 62.0
TLS3_k127_3034642_8 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000002271 54.0
TLS3_k127_304256_0 Metal-dependent phosphohydrolase, HD region - - - 0.000000000000000000000000000000000000000000000000000002074 207.0
TLS3_k127_304256_1 - - - - 0.000000000000000000000000000000001556 141.0
TLS3_k127_304256_2 - - - - 0.00000000000000000000000000001788 119.0
TLS3_k127_304256_3 - - - - 0.0000000000000000000000000002289 123.0
TLS3_k127_304256_4 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.0000000000000001917 90.0
TLS3_k127_304256_5 - - - - 0.0000000000000856 73.0
TLS3_k127_304256_6 deoxyhypusine monooxygenase activity - - - 0.000000001973 65.0
TLS3_k127_304256_7 protein related to plant photosystem II stability assembly factor - - - 0.00007484 49.0
TLS3_k127_3095923_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 6.235e-200 635.0
TLS3_k127_3095923_1 Colicin V production protein - - - 0.0000000000000000000000000000000000000000000000000000000000003758 226.0
TLS3_k127_3095923_2 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000005811 207.0
TLS3_k127_3095923_3 Helix-hairpin-helix motif K02237 - - 0.00000000000000000000000000000000000005126 150.0
TLS3_k127_3098_0 NAD dependent epimerase dehydratase family protein K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008338 311.0
TLS3_k127_3098_1 pyridine nucleotide-disulphide oxidoreductase K00529,K05301,K17229 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.18.1.3,1.8.2.1,1.8.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003995 271.0
TLS3_k127_3098_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001828 235.0
TLS3_k127_3098_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000002121 232.0
TLS3_k127_3098_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000366 156.0
TLS3_k127_3098_5 Cytochrome c K05301 - 1.8.2.1 0.00000000000164 74.0
TLS3_k127_3098_6 domain protein K21687 - - 0.00000001497 65.0
TLS3_k127_3118958_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1018.0
TLS3_k127_3118958_1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 551.0
TLS3_k127_3118958_2 protein, probably involved in trehalose biosynthesis - - - 0.00000000003473 63.0
TLS3_k127_3162625_0 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 449.0
TLS3_k127_3162625_1 Diacylglycerol kinase - - - 0.000000000000000000000000000000002177 139.0
TLS3_k127_3162625_2 PFAM Transketolase central region K00162 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 1.2.4.1 0.00000000304 61.0
TLS3_k127_323341_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 387.0
TLS3_k127_323341_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000005618 222.0
TLS3_k127_323341_2 protein conserved in bacteria K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000007014 193.0
TLS3_k127_323341_3 Ribosomal protein L20 K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904 - 0.0000000000000000000000000000000000001082 148.0
TLS3_k127_323341_4 tRNA rRNA methyltransferase, SpoU K03437 - - 0.0000000000000000000000000000000007306 149.0
TLS3_k127_323341_5 SnoaL-like domain - - - 0.00000000000000000000000001381 126.0
TLS3_k127_323341_6 membrane protein (DUF2207) - - - 0.00000000000000000000006874 112.0
TLS3_k127_323341_7 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000002035 70.0
TLS3_k127_3300211_0 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 2.678e-203 653.0
TLS3_k127_3300211_1 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 391.0
TLS3_k127_3300211_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 337.0
TLS3_k127_3300211_3 peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000000000000002371 241.0
TLS3_k127_3300211_4 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000001514 225.0
TLS3_k127_3300211_5 - - - - 0.000000000000000000002486 101.0
TLS3_k127_3300211_6 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000004398 88.0
TLS3_k127_3364667_0 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004458 279.0
TLS3_k127_3364667_1 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.000000000000000000000000000000000000000001491 170.0
TLS3_k127_3365831_0 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000002434 224.0
TLS3_k127_3365831_1 O-Antigen ligase - - - 0.0000000000000000000004458 107.0
TLS3_k127_3446995_0 PFAM ABC transporter related K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 331.0
TLS3_k127_3446995_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31,3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000003371 273.0
TLS3_k127_3446995_2 TIGRFAM FeS assembly protein SufB K07033,K09014 - - 0.0000000000000000000000000000000000000000000000000000000000000005292 222.0
TLS3_k127_3446995_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000001013 131.0
TLS3_k127_3446995_4 Belongs to the anti-sigma-factor antagonist family K04749 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000002231 124.0
TLS3_k127_3446995_5 PFAM blue (type 1) copper domain protein K07243 - - 0.000000000001614 77.0
TLS3_k127_3446995_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000002391 71.0
TLS3_k127_3446995_7 Cytochrome c K05301 - 1.8.2.1 0.00000000002398 73.0
TLS3_k127_3486004_0 Zn_pept - - - 0.0 1164.0
TLS3_k127_3486004_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.195e-286 897.0
TLS3_k127_3486004_2 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 504.0
TLS3_k127_3486004_3 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 464.0
TLS3_k127_3486004_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000001587 290.0
TLS3_k127_3486004_5 - - - - 0.000000000000000000000000000000009822 135.0
TLS3_k127_3526083_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 367.0
TLS3_k127_3526083_1 RNA pseudouridylate synthase K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000004658 237.0
TLS3_k127_3526083_2 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.0000000000000000000000000000000000000000000000000008215 186.0
TLS3_k127_3526083_3 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000007986 159.0
TLS3_k127_3526083_4 GYD domain - - - 0.0000000000000000237 89.0
TLS3_k127_3526083_5 Segregation and condensation complex subunit ScpB K06024 - - 0.000000001233 61.0
TLS3_k127_3533059_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 497.0
TLS3_k127_3533059_1 Peptidase family M41 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 486.0
TLS3_k127_3533059_2 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000002951 194.0
TLS3_k127_3533059_3 Peptidase dimerisation domain - - - 0.0000000000000000000003893 100.0
TLS3_k127_3536718_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 464.0
TLS3_k127_3536718_1 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 300.0
TLS3_k127_3536718_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000003049 171.0
TLS3_k127_3536718_3 Domain of unknown function (DUF4190) - - - 0.0000000000009196 78.0
TLS3_k127_3536718_4 SAICAR synthetase K01923 - 6.3.2.6 0.00002382 57.0
TLS3_k127_3548942_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 6.699e-276 875.0
TLS3_k127_3548942_1 Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 391.0
TLS3_k127_3548942_2 Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine K18912 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0055114,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.14.99.50 0.000000000000000000000000000000000601 153.0
TLS3_k127_3548942_3 heavy metal translocating P-type ATPase K01533,K17686,K21887 - 3.6.3.4,3.6.3.54 0.0000000000000000000000000004128 120.0
TLS3_k127_3548942_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000004077 66.0
TLS3_k127_3567400_0 TrwC relaxase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 518.0
TLS3_k127_3567400_1 RHS Repeat - - - 0.00000000000000000000000000000000000000000000000000001216 216.0
TLS3_k127_3567400_2 Belongs to the 'phage' integrase family K14059 - - 0.0000000000000000000000000000676 132.0
TLS3_k127_3567400_3 COGs COG1318 transcriptional regulator protein K07745,K18546 - - 0.000000000000000000003227 110.0
TLS3_k127_3567400_4 - - - - 0.0000000000000001584 87.0
TLS3_k127_35726_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 434.0
TLS3_k127_35726_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 392.0
TLS3_k127_35726_2 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 360.0
TLS3_k127_35726_3 Carbon-nitrogen hydrolase K01501 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000475 286.0
TLS3_k127_35726_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000006845 217.0
TLS3_k127_35726_5 transcription factor binding - - - 0.00000000000000000000000000000000000000001623 157.0
TLS3_k127_35726_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000003048 106.0
TLS3_k127_35726_7 translation release factor activity K03265 - - 0.0000000000000000000001768 110.0
TLS3_k127_35726_8 Protein of unknown function (DUF3105) - - - 0.00000000000000006819 90.0
TLS3_k127_35726_9 NfeD-like C-terminal, partner-binding K07403 - - 0.000000001039 63.0
TLS3_k127_3574121_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 450.0
TLS3_k127_3574121_1 ATP dependent DNA ligase C terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001786 279.0
TLS3_k127_3574121_2 HAD-superfamily hydrolase, subfamily IA - - - 0.000000000000000000000000000000000000000000000000000000000000001662 234.0
TLS3_k127_3574121_3 TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000001698 179.0
TLS3_k127_3574121_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000001188 88.0
TLS3_k127_3574121_5 Repeats in polycystic kidney disease 1 (PKD1) and other proteins K01126,K01181 - 3.1.4.46,3.2.1.8 0.0000000000000008316 87.0
TLS3_k127_3574121_6 PA26 p53-induced protein (sestrin) - - - 0.00000000000004172 82.0
TLS3_k127_3575282_0 the transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 504.0
TLS3_k127_3575282_1 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 417.0
TLS3_k127_3575282_2 ABC transporter, ATP-binding protein K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008571 323.0
TLS3_k127_3575282_3 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000003462 228.0
TLS3_k127_3575282_4 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000004891 126.0
TLS3_k127_3575282_5 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000894 118.0
TLS3_k127_3575282_6 Transglycosylase associated protein - - - 0.00000000000000000000003405 116.0
TLS3_k127_3575282_7 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000001069 72.0
TLS3_k127_3576932_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000002191 276.0
TLS3_k127_3576932_1 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000000000000000005363 201.0
TLS3_k127_3576932_2 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000002162 160.0
TLS3_k127_3576932_3 Binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000974 146.0
TLS3_k127_3576932_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000002015 111.0
TLS3_k127_3576932_5 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000008317 85.0
TLS3_k127_3576932_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000002276 65.0
TLS3_k127_3607206_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 604.0
TLS3_k127_3607206_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 571.0
TLS3_k127_3607206_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000009111 202.0
TLS3_k127_3610388_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 455.0
TLS3_k127_3610388_1 UV-endonuclease UvdE K13281 - - 0.000000000000000000000000000000000000000000000000000000000000000000003719 249.0
TLS3_k127_3610388_2 Putative peptidoglycan binding domain - - - 0.000000000000000000000001516 113.0
TLS3_k127_3610388_3 chitinase K01183 - 3.2.1.14 0.0002151 48.0
TLS3_k127_3623913_0 Fungalysin metallopeptidase (M36) - - - 0.0 1045.0
TLS3_k127_3623913_1 Fungalysin metallopeptidase (M36) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 349.0
TLS3_k127_3623913_2 Fungalysin metallopeptidase (M36) - - - 0.000000000000000000000000000000000000000000673 162.0
TLS3_k127_3637336_0 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 501.0
TLS3_k127_3637336_1 vancomycin resistance protein - - - 0.00000000000000000000000000000000000000000000000000000006926 219.0
TLS3_k127_3637336_2 glycoside hydrolase, family K01207 - 3.2.1.52 0.00000000000000000000000000000003104 137.0
TLS3_k127_3637336_3 Cupin domain - - - 0.00000000001467 71.0
TLS3_k127_3641541_0 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 598.0
TLS3_k127_3641541_1 PFAM SMP-30 Gluconolaconase K14274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003866 265.0
TLS3_k127_3641541_2 Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a modified Entner-Doudoroff pathway K00068,K18124,K18125 GO:0000166,GO:0003674,GO:0003824,GO:0004344,GO:0005488,GO:0005515,GO:0005534,GO:0005536,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006012,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019318,GO:0019320,GO:0019388,GO:0019595,GO:0022607,GO:0030246,GO:0033498,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046430,GO:0046872,GO:0046914,GO:0046983,GO:0047910,GO:0047936,GO:0048029,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051262,GO:0051287,GO:0055114,GO:0065003,GO:0070401,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.1.1.140,1.1.1.359,1.1.1.360 0.0000000000000000000000000000000000000000000000000000000000000000000000000008187 267.0
TLS3_k127_3641541_3 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000005301 227.0
TLS3_k127_3641541_4 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000002824 227.0
TLS3_k127_3641541_5 - - - - 0.000000002674 60.0
TLS3_k127_3709295_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 336.0
TLS3_k127_3709295_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002304 294.0
TLS3_k127_3709295_2 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000001372 176.0
TLS3_k127_3709295_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000005701 84.0
TLS3_k127_3709295_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000004705 73.0
TLS3_k127_3714371_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 329.0
TLS3_k127_3714371_1 response regulator receiver K07668,K07775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000128 246.0
TLS3_k127_3714371_2 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000004768 241.0
TLS3_k127_3714371_3 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000000000000000005732 209.0
TLS3_k127_3714371_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000903 188.0
TLS3_k127_3714371_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000006271 155.0
TLS3_k127_3714371_6 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000005503 141.0
TLS3_k127_3715703_0 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 368.0
TLS3_k127_3715703_1 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000001483 198.0
TLS3_k127_3715703_2 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000001596 195.0
TLS3_k127_3715703_3 YceI-like domain - - - 0.00000000000000000000000000000000003211 141.0
TLS3_k127_3715703_4 COGs COG3593 ATP-dependent endonuclease of the OLD family K07459 - - 0.000000000000000000000000000007835 134.0
TLS3_k127_3715703_5 Hemerythrin HHE cation binding domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000008648 84.0
TLS3_k127_3715703_6 MarR family - - - 0.00000000000000008833 92.0
TLS3_k127_3717884_0 glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 454.0
TLS3_k127_3717884_1 Cys/Met metabolism PLP-dependent enzyme K01760,K01761 - 4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009619 317.0
TLS3_k127_3717884_2 HAD-superfamily hydrolase, subfamily IA, variant K07025 - - 0.000000000000000000000000002492 120.0
TLS3_k127_3717884_3 mechanosensitive ion channel - - - 0.0000000000000000000000003875 119.0
TLS3_k127_3717884_4 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000004137 96.0
TLS3_k127_3717884_5 CAAX protease self-immunity K07052 - - 0.000000000003404 76.0
TLS3_k127_3717884_6 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.00000001362 68.0
TLS3_k127_3726578_0 Fungalysin metallopeptidase (M36) - - - 2.935e-286 909.0
TLS3_k127_3726578_1 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 587.0
TLS3_k127_3726578_2 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 424.0
TLS3_k127_3726578_3 Oligoendopeptidase f K01283 - 3.4.15.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 380.0
TLS3_k127_3726578_4 PHP-associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 351.0
TLS3_k127_3726578_5 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000002936 252.0
TLS3_k127_3726578_6 Uracil DNA glycosylase superfamily - - - 0.00000000000000000000000000000000000000000000000009767 201.0
TLS3_k127_3726578_7 EamA-like transporter family - - - 0.000000000000000000000000000000000000127 152.0
TLS3_k127_3726578_8 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000006641 152.0
TLS3_k127_3726578_9 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000001285 122.0
TLS3_k127_3730025_0 Cleaves the N-terminal amino acid of tripeptides K01258 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0034701,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045148,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 446.0
TLS3_k127_3730025_2 PFAM Peptidase M1 membrane alanine aminopeptidase - - - 0.0000000000000000000000000000000000000000003418 160.0
TLS3_k127_3730025_3 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000004456 152.0
TLS3_k127_3730025_4 - - - - 0.0000000000000001611 83.0
TLS3_k127_3730025_5 - - - - 0.0000000000001105 84.0
TLS3_k127_3735480_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.277e-196 629.0
TLS3_k127_3735480_1 Lysyl oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002257 297.0
TLS3_k127_3735480_2 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000001402 200.0
TLS3_k127_3735480_3 Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant K06720 - 4.2.1.108 0.000000000000000000000000000002433 124.0
TLS3_k127_3735480_4 diguanylate cyclase - - - 0.00000000000001214 85.0
TLS3_k127_3735959_0 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 610.0
TLS3_k127_3735959_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 0.00000000000000000000000000000000000000000000000000022 190.0
TLS3_k127_3740197_0 hydrolase, family 65, central catalytic K10231 - 2.4.1.230 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 579.0
TLS3_k127_3740197_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001804 275.0
TLS3_k127_3740197_2 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000001375 183.0
TLS3_k127_3744894_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 396.0
TLS3_k127_3744894_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 349.0
TLS3_k127_3744894_2 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 297.0
TLS3_k127_3744894_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000002392 228.0
TLS3_k127_3744894_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000001519 185.0
TLS3_k127_3744894_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000004325 130.0
TLS3_k127_3745639_0 amine oxidase K06954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 374.0
TLS3_k127_3745639_1 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003836 291.0
TLS3_k127_3745639_2 synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000006885 251.0
TLS3_k127_3745639_3 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000000000000002255 192.0
TLS3_k127_3745639_4 Alpha/beta hydrolase family - - - 0.000000000009105 70.0
TLS3_k127_37586_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 385.0
TLS3_k127_37586_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000001267 242.0
TLS3_k127_37586_2 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000002147 202.0
TLS3_k127_37586_3 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000001268 129.0
TLS3_k127_37586_4 cheY-homologous receiver domain - - - 0.0000000000000000000000000002157 119.0
TLS3_k127_37586_5 Involved in the tonB-independent uptake of proteins - - - 0.00000000000009275 84.0
TLS3_k127_3787240_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 391.0
TLS3_k127_3787240_1 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000001128 160.0
TLS3_k127_3787240_2 Metal-dependent phosphohydrolase, HD region - - - 0.0000007856 63.0
TLS3_k127_3787240_3 Histidine kinase - - - 0.00000935 60.0
TLS3_k127_3836735_0 UDP-N-acetylglucosamine 2-epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 375.0
TLS3_k127_3836735_1 Homoserine dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001368 293.0
TLS3_k127_3836735_2 Hexapeptide repeat of succinyl-transferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000009421 235.0
TLS3_k127_3845969_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 422.0
TLS3_k127_3845969_1 MMPL family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 378.0
TLS3_k127_3845969_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 330.0
TLS3_k127_3846681_0 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008236 332.0
TLS3_k127_3846681_1 cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006447 302.0
TLS3_k127_3846681_2 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002108 263.0
TLS3_k127_3846681_3 Putative modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000006819 258.0
TLS3_k127_3846681_4 Sigma-70 region 2 K03091 - - 0.000000000000000000000000000000000000000000000000000000000005957 211.0
TLS3_k127_3846681_5 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000005287 106.0
TLS3_k127_3846681_6 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000001974 58.0
TLS3_k127_3846740_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 1.438e-208 657.0
TLS3_k127_3846740_1 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006175 252.0
TLS3_k127_3846740_2 Amidohydrolase family - - - 0.0000000000000005323 81.0
TLS3_k127_3846740_3 Belongs to the pyrroline-5-carboxylate reductase family K00286 - 1.5.1.2 0.0007745 42.0
TLS3_k127_3858908_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 424.0
TLS3_k127_3858908_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 377.0
TLS3_k127_3858908_10 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000008894 61.0
TLS3_k127_3858908_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 351.0
TLS3_k127_3858908_3 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 344.0
TLS3_k127_3858908_4 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 333.0
TLS3_k127_3858908_5 Aldehyde dehydrogenase K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 319.0
TLS3_k127_3858908_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 310.0
TLS3_k127_3858908_7 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 293.0
TLS3_k127_3858908_8 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 299.0
TLS3_k127_3858908_9 DNA polymerase K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000008048 242.0
TLS3_k127_3886107_0 Carbamoyltransferase C-terminus K00612 - - 5.307e-266 829.0
TLS3_k127_3886107_1 HAD-hyrolase-like K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 595.0
TLS3_k127_3886107_2 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007614 270.0
TLS3_k127_3886107_3 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000002767 177.0
TLS3_k127_392443_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 337.0
TLS3_k127_392443_1 Riboflavin biosynthesis protein RibD K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 302.0
TLS3_k127_392443_2 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006906 290.0
TLS3_k127_392443_3 riboflavin synthase, alpha K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000001406 190.0
TLS3_k127_392443_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000002887 173.0
TLS3_k127_3939930_0 Homocysteine S-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 598.0
TLS3_k127_3939930_1 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000000000000000000000005875 198.0
TLS3_k127_3939930_2 Cobalamin-independent synthase, Catalytic domain - - - 0.00000000000000000000000000000000000000000000002641 173.0
TLS3_k127_3963307_0 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000001648 268.0
TLS3_k127_3963307_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000003549 161.0
TLS3_k127_3963307_2 TIGRFAM molybdenum cofactor synthesis domain K03635 - 2.8.1.12 0.000000000000000000000000000000000000000005841 168.0
TLS3_k127_3963307_3 heme ABC exporter, ATP-binding protein CcmA K02193 - 3.6.3.41 0.000000000000000000000000000000001256 148.0
TLS3_k127_3963307_4 CcmB protein K02194 - - 0.00000000000000002773 94.0
TLS3_k127_3984004_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 366.0
TLS3_k127_3984004_1 PFAM aminotransferase class V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 351.0
TLS3_k127_3984004_10 Putative zinc-finger - - - 0.000009252 51.0
TLS3_k127_3984004_11 LytR cell envelope-related transcriptional attenuator - - - 0.00004657 55.0
TLS3_k127_3984004_12 3-hydroxyanthranilate 3,4-dioxygenase activity - - - 0.00006284 55.0
TLS3_k127_3984004_13 - - - - 0.0004976 53.0
TLS3_k127_3984004_2 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 347.0
TLS3_k127_3984004_3 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002842 279.0
TLS3_k127_3984004_4 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000009721 219.0
TLS3_k127_3984004_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000005497 152.0
TLS3_k127_3984004_6 Cupin - - - 0.0000000000000000000000000000000000000699 145.0
TLS3_k127_3984004_7 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000000000000001788 119.0
TLS3_k127_3984004_8 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.0000000000000000000000005723 119.0
TLS3_k127_3984004_9 penicillin amidase K01434 - 3.5.1.11 0.000000000004048 67.0
TLS3_k127_4020982_0 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003846 242.0
TLS3_k127_4020982_1 - - - - 0.0000003954 53.0
TLS3_k127_4127746_0 Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine K18911 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008213,GO:0008276,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0019439,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0036211,GO:0042398,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052707,GO:0052708,GO:0052709,GO:0052803,GO:0052805,GO:0071704,GO:0071944,GO:0097164,GO:0140096,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 381.0
TLS3_k127_4127746_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 302.0
TLS3_k127_4127746_2 Putative tRNA binding domain K06878 - - 0.00000000000000000000000000000000412 138.0
TLS3_k127_4127746_3 - - - - 0.00000000000000000000000001459 126.0
TLS3_k127_4127746_4 Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine K18912 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0055114,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.14.99.50 0.00000000000000000000003031 98.0
TLS3_k127_4164503_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009392 484.0
TLS3_k127_4164503_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000002971 159.0
TLS3_k127_4164503_2 - - - - 0.0000000000000000000000000000000236 128.0
TLS3_k127_4164503_3 COG0662 Mannose-6-phosphate isomerase - - - 0.0000000000008858 80.0
TLS3_k127_4164503_4 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.000000005963 58.0
TLS3_k127_4212589_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 368.0
TLS3_k127_4212589_1 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000005934 222.0
TLS3_k127_4212589_2 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000001602 139.0
TLS3_k127_4212589_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000005678 128.0
TLS3_k127_4212589_4 Zincin-like metallopeptidase - - - 0.000000000000000000000000000004459 136.0
TLS3_k127_4212589_5 RDD family - - - 0.000003172 49.0
TLS3_k127_4305513_0 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 387.0
TLS3_k127_4305513_1 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000007354 190.0
TLS3_k127_4312071_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.072e-263 833.0
TLS3_k127_4312071_1 Arylsulfatase a K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 330.0
TLS3_k127_4312071_2 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.000000000000000000000008626 102.0
TLS3_k127_4329950_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000007292 175.0
TLS3_k127_4329950_1 Cupin - - - 0.000000000000000000000000000000008322 139.0
TLS3_k127_4329950_2 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000003841 142.0
TLS3_k127_4329950_3 GCN5-related N-acetyl-transferase K06975 - - 0.00000000000000000001082 104.0
TLS3_k127_4329950_4 Permeases of the drug metabolite transporter DMT superfamily - - - 0.000000003618 65.0
TLS3_k127_4357649_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004406 261.0
TLS3_k127_4357649_1 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000001635 133.0
TLS3_k127_4393822_0 Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP K05716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 381.0
TLS3_k127_4393822_1 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 330.0
TLS3_k127_4393822_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 307.0
TLS3_k127_4393822_3 fructose-1,6-bisphosphatase K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 294.0
TLS3_k127_4393822_4 2-phosphoglycerate kinase K05715 - - 0.00000000000000000000000000000000000000000000000000002181 213.0
TLS3_k127_4393822_5 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.00000000000000000000000000000000000000001188 163.0
TLS3_k127_4393822_6 Psort location Cytoplasmic, score K00760 - 2.4.2.8 0.0000000000000000000000000000001024 129.0
TLS3_k127_4393822_7 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000001923 128.0
TLS3_k127_4393822_8 Iron-sulfur cluster assembly protein - - - 0.000000000000000000000002415 118.0
TLS3_k127_4429566_0 Domain of unknown function (DUF4389) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007579 424.0
TLS3_k127_4429566_1 Acetokinase family K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 315.0
TLS3_k127_4429566_2 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 296.0
TLS3_k127_4429566_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000009707 209.0
TLS3_k127_4429566_4 alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000001402 205.0
TLS3_k127_4429566_5 Serine aminopeptidase, S33 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000001289 108.0
TLS3_k127_4429566_6 Predicted membrane protein (DUF2231) - - - 0.000000000000008687 81.0
TLS3_k127_4444506_0 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 543.0
TLS3_k127_4444506_1 Glycosyl transferase family 2 K00786 - - 0.00000000000000000000000000000000005892 146.0
TLS3_k127_4445952_0 Serine dehydrogenase proteinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 325.0
TLS3_k127_4445952_1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000007431 241.0
TLS3_k127_4445952_2 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000001465 233.0
TLS3_k127_4445952_3 CHRD domain - - - 0.000000000000000000000000000000000009683 143.0
TLS3_k127_4445952_4 Belongs to the thioredoxin family K03671 - - 0.00000000003605 67.0
TLS3_k127_4474397_0 Myo-inositol-1-phosphate synthase K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 561.0
TLS3_k127_4474397_1 PFAM cyclase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008749 257.0
TLS3_k127_4474397_2 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000006678 123.0
TLS3_k127_4474397_3 Fungalysin metallopeptidase (M36) - - - 0.00000000000000000000003767 101.0
TLS3_k127_4474397_4 PAP2 superfamily - - - 0.0008326 44.0
TLS3_k127_4523064_0 Glutamine amidotransferase domain K22081 - 2.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 366.0
TLS3_k127_4523064_1 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 320.0
TLS3_k127_4523064_2 Glutamate synthase K22082 - 2.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 313.0
TLS3_k127_4539444_0 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 622.0
TLS3_k127_4539444_1 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006798 443.0
TLS3_k127_4539444_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 407.0
TLS3_k127_4539444_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000002597 93.0
TLS3_k127_457022_0 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 330.0
TLS3_k127_457022_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000000000000000000000000000000000000000000000005353 215.0
TLS3_k127_457022_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000000000000000000000000006138 203.0
TLS3_k127_457022_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000003529 127.0
TLS3_k127_457022_4 PFAM Bacterial membrane flanked domain - - - 0.0000004169 60.0
TLS3_k127_457022_5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0003196 46.0
TLS3_k127_4612768_0 ATP-grasp - - - 0.00000000000000000000000000000000000000004011 166.0
TLS3_k127_4612768_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000002907 162.0
TLS3_k127_4612768_2 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000657 141.0
TLS3_k127_4616665_0 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 338.0
TLS3_k127_4616665_1 Ornithine cyclodeaminase/mu-crystallin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003287 269.0
TLS3_k127_4616665_2 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000386 130.0
TLS3_k127_4616665_3 translation initiation factor activity - - - 0.00000000000004586 85.0
TLS3_k127_4616665_4 HMGL-like K18314 - 4.1.3.46 0.00000000000479 67.0
TLS3_k127_4643279_0 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 418.0
TLS3_k127_4643279_1 Belongs to the aldehyde dehydrogenase family K00146 - 1.2.1.39 0.00000000000000000000000000000000000000000000000000000000000000000001044 241.0
TLS3_k127_4643279_2 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K02083 - 3.5.3.9 0.00000000000000000000000000000000000000000000000000000000000000001138 247.0
TLS3_k127_4643279_3 Protein of unknown function (DUF3830) - - - 0.0000000000000000000000000000000000000000000000000000000004226 204.0
TLS3_k127_4643279_4 OHCU decarboxylase - - - 0.00000000000000002313 89.0
TLS3_k127_4643279_5 thyroid hormone binding K07127,K13484,K20731 GO:0000255,GO:0001558,GO:0001560,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005829,GO:0005886,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009605,GO:0009719,GO:0009725,GO:0009741,GO:0009742,GO:0009755,GO:0009898,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016043,GO:0016787,GO:0016810,GO:0016812,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0018130,GO:0019428,GO:0019897,GO:0019898,GO:0022607,GO:0023052,GO:0031234,GO:0031668,GO:0032870,GO:0033971,GO:0033993,GO:0034641,GO:0040008,GO:0042221,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043401,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0048545,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0051997,GO:0055086,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071367,GO:0071383,GO:0071396,GO:0071407,GO:0071495,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0098552,GO:0098562,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1901701 3.5.2.17,4.1.1.97 0.000004869 49.0
TLS3_k127_464360_0 Protein-disulfide isomerase - - - 0.0000000000000000000000000000000000000000002322 170.0
TLS3_k127_464360_1 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000006837 147.0
TLS3_k127_464360_2 VKc - - - 0.000000000000964 81.0
TLS3_k127_465913_0 dihydrolipoyl dehydrogenase activity K00382 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0005759,GO:0005967,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006549,GO:0006550,GO:0006551,GO:0006552,GO:0006563,GO:0006564,GO:0006573,GO:0006574,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009081,GO:0009083,GO:0009507,GO:0009536,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016053,GO:0016054,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0017144,GO:0019752,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0042737,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045254,GO:0045271,GO:0046394,GO:0046395,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0070469,GO:0071704,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1902494,GO:1990204 1.8.1.4 0.000000000000000000000000000000000001044 142.0
TLS3_k127_465913_1 Transmembrane secretion effector - - - 0.0000000000000000001637 103.0
TLS3_k127_465913_2 Family of unknown function (DUF5317) - - - 0.000000000004242 79.0
TLS3_k127_465913_3 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001,K19745 - 1.1.1.1 0.0001034 53.0
TLS3_k127_4672561_0 Anticodon-binding domain of tRNA K01870 - 6.1.1.5 1.675e-264 843.0
TLS3_k127_4672561_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 366.0
TLS3_k127_4672561_2 Beta-lactamase class C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 350.0
TLS3_k127_4672561_3 belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000001785 133.0
TLS3_k127_4672561_4 polyketide cyclase - - - 0.000000000000000000000000000000001813 145.0
TLS3_k127_4672561_5 Redoxin K03564 - 1.11.1.15 0.00000000000000000008036 104.0
TLS3_k127_4672561_6 cAMP-dependent protein kinase regulator activity K04739 GO:0000086,GO:0000166,GO:0000278,GO:0001664,GO:0001674,GO:0001932,GO:0001933,GO:0001934,GO:0003008,GO:0003014,GO:0003091,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0005886,GO:0005929,GO:0005952,GO:0006082,GO:0006469,GO:0006629,GO:0006631,GO:0006950,GO:0006996,GO:0007049,GO:0007154,GO:0007165,GO:0007346,GO:0007596,GO:0007599,GO:0007610,GO:0007611,GO:0007612,GO:0008150,GO:0008152,GO:0008603,GO:0009410,GO:0009611,GO:0009719,GO:0009725,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010389,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010720,GO:0014070,GO:0015630,GO:0016020,GO:0016043,GO:0017076,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019752,GO:0019866,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0022402,GO:0022406,GO:0022607,GO:0023052,GO:0030030,GO:0030031,GO:0030104,GO:0030234,GO:0030291,GO:0030315,GO:0030425,GO:0030551,GO:0030552,GO:0030554,GO:0031090,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0031588,GO:0031625,GO:0031690,GO:0031698,GO:0031966,GO:0031967,GO:0031975,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032870,GO:0032991,GO:0033673,GO:0033674,GO:0033762,GO:0034199,GO:0034236,GO:0035556,GO:0036094,GO:0036477,GO:0042060,GO:0042221,GO:0042325,GO:0042326,GO:0042327,GO:0042383,GO:0042493,GO:0042585,GO:0042592,GO:0042802,GO:0042803,GO:0042995,GO:0043005,GO:0043025,GO:0043073,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043197,GO:0043198,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043434,GO:0043436,GO:0043549,GO:0043900,GO:0043902,GO:0043933,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044297,GO:0044309,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0044770,GO:0044772,GO:0044782,GO:0044839,GO:0044853,GO:0045121,GO:0045202,GO:0045595,GO:0045597,GO:0045787,GO:0045859,GO:0045860,GO:0045936,GO:0045937,GO:0046983,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048871,GO:0048878,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050817,GO:0050877,GO:0050878,GO:0050890,GO:0050891,GO:0050896,GO:0051018,GO:0051094,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051259,GO:0051291,GO:0051338,GO:0051347,GO:0051348,GO:0051445,GO:0051446,GO:0051640,GO:0051641,GO:0051716,GO:0051726,GO:0060255,GO:0060271,GO:0060281,GO:0060282,GO:0060284,GO:0061695,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0070925,GO:0071310,GO:0071375,GO:0071377,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071900,GO:0071901,GO:0071944,GO:0080090,GO:0090068,GO:0097159,GO:0097332,GO:0097338,GO:0097367,GO:0097447,GO:0097458,GO:0097546,GO:0097711,GO:0098589,GO:0098590,GO:0098772,GO:0098794,GO:0098805,GO:0098857,GO:0120025,GO:0120031,GO:0120036,GO:0120038,GO:0140056,GO:1900193,GO:1900195,GO:1901265,GO:1901363,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901987,GO:1901990,GO:1902494,GO:1902749,GO:1902911,GO:1903047,GO:1903429,GO:1903431,GO:1903538,GO:1904146,GO:1905879,GO:1905881,GO:1990234,GO:2000241,GO:2000243,GO:2000479,GO:2000480 - 0.0000000000002807 77.0
TLS3_k127_4692173_0 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002121 281.0
TLS3_k127_4692173_1 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001384 290.0
TLS3_k127_4719_0 Tubulin/FtsZ family, GTPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 424.0
TLS3_k127_4719_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 414.0
TLS3_k127_4719_10 Putative diguanylate phosphodiesterase - - - 0.0000000006626 70.0
TLS3_k127_4719_2 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 365.0
TLS3_k127_4719_3 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 342.0
TLS3_k127_4719_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 295.0
TLS3_k127_4719_5 peptidase M36 K01417 - - 0.0000000000000000000000000000000000000000000002632 192.0
TLS3_k127_4719_6 Domain of unknown function (DUF4383) - - - 0.00000000000000000000000000000000000000001791 163.0
TLS3_k127_4719_7 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.00000000000000000000000000000000000000003216 159.0
TLS3_k127_4719_8 Acetyltransferase (GNAT) domain K03825 - - 0.000000000000006155 87.0
TLS3_k127_4719_9 - - - - 0.0000000001215 73.0
TLS3_k127_4765251_0 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 290.0
TLS3_k127_4765251_1 NUDIX hydrolase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 288.0
TLS3_k127_4765251_2 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000008557 217.0
TLS3_k127_4797915_0 DEAD/H associated K03724 - - 5.353e-259 817.0
TLS3_k127_4797915_1 Formamidopyrimidine-DNA glycosylase H2TH domain - - - 0.0000000000000000000000000000000000000000000000001631 190.0
TLS3_k127_4797915_2 CBD_II K01179,K01183 - 3.2.1.14,3.2.1.4 0.0000000000000000000000000000000000000000000004797 190.0
TLS3_k127_4815213_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 338.0
TLS3_k127_4815213_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000003857 153.0
TLS3_k127_4815213_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000001413 136.0
TLS3_k127_4815213_3 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000001335 116.0
TLS3_k127_4815213_4 ECF sigma factor K03088 - - 0.0000000000000001664 87.0
TLS3_k127_4815213_5 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000001719 63.0
TLS3_k127_4830471_0 Pyridine nucleotide-disulphide oxidoreductase K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 371.0
TLS3_k127_4830471_1 Alpha Beta K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 327.0
TLS3_k127_4830471_2 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003359 269.0
TLS3_k127_4830471_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003294 235.0
TLS3_k127_4830471_4 DNA binding - - - 0.000000000000000000000000000000000000000000001522 177.0
TLS3_k127_4874865_0 The glycine cleavage system catalyzes the degradation of glycine - - - 9.39e-248 823.0
TLS3_k127_4874865_1 acyl-CoA dehydrogenase - - - 9.242e-231 722.0
TLS3_k127_4874865_2 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006546 287.0
TLS3_k127_4874865_3 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000001547 175.0
TLS3_k127_4874865_4 PAS domain - - - 0.000000000004009 78.0
TLS3_k127_4888176_0 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits K16881 - 2.7.7.13,5.4.2.8 7.372e-210 700.0
TLS3_k127_4888176_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 298.0
TLS3_k127_4888176_2 Forkhead associated domain - - - 0.0000000000000000000000000000000000002472 144.0
TLS3_k127_4888176_3 CDP-alcohol phosphatidyltransferase K00995,K08744 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.00000000000000000000007643 108.0
TLS3_k127_4888176_4 - - - - 0.00000000000000003095 84.0
TLS3_k127_4917044_0 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972 449.0
TLS3_k127_4917044_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 347.0
TLS3_k127_4917044_2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001419 287.0
TLS3_k127_4917044_3 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000002526 191.0
TLS3_k127_4917044_4 cellulose binding - - - 0.00000000000000000000000000006043 119.0
TLS3_k127_4917044_5 Transcriptional regulatory protein, C terminal - - - 0.0000000000002715 74.0
TLS3_k127_493593_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 354.0
TLS3_k127_493593_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000006128 231.0
TLS3_k127_493593_2 Conserved TM helix - - - 0.0000000000000000000000000000000000000000000000000000000002854 214.0
TLS3_k127_493593_3 PFAM extracellular solute-binding protein, family 5 K15580 - - 0.000000000000000000000000000000000000000000000000003653 209.0
TLS3_k127_493593_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000003792 183.0
TLS3_k127_4985721_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 476.0
TLS3_k127_4985721_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009136 326.0
TLS3_k127_5029438_0 Mandelate Racemase Muconate Lactonizing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 437.0
TLS3_k127_5029438_1 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 302.0
TLS3_k127_5029438_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000008623 221.0
TLS3_k127_5029438_3 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000222 188.0
TLS3_k127_5029438_4 - - - - 0.00000000000000000000000000000000000001622 148.0
TLS3_k127_5029438_5 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000002792 130.0
TLS3_k127_5029438_6 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000006101 76.0
TLS3_k127_5029438_7 - - - - 0.0001491 49.0
TLS3_k127_5056754_0 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483 - 1.14.14.9 1.54e-201 658.0
TLS3_k127_5056754_1 Belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006005 525.0
TLS3_k127_5056754_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000004771 176.0
TLS3_k127_5056754_3 Flavin reductase like domain - - - 0.0000000000000000000000000000000007892 150.0
TLS3_k127_5065546_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002836 276.0
TLS3_k127_5065546_1 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001027 244.0
TLS3_k127_5065546_2 epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001992 239.0
TLS3_k127_5065546_3 cellulase activity - - - 0.00000000000000000000002585 115.0
TLS3_k127_5065546_4 - - - - 0.00000000000000000000538 94.0
TLS3_k127_5065546_7 Beta-galactosidase - - - 0.000000000369 72.0
TLS3_k127_5065546_8 oxidoreductase activity K06921 - - 0.000008567 58.0
TLS3_k127_5082411_0 Seryl-tRNA synthetase N-terminal domain K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 490.0
TLS3_k127_5082411_1 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 452.0
TLS3_k127_5082411_10 Protein of unknown function (DUF429) - - - 0.0000000000000000000000000000000006175 139.0
TLS3_k127_5082411_11 Domain of unknown function (DUF4260) - - - 0.00000000000000000000000000000193 132.0
TLS3_k127_5082411_12 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000009441 101.0
TLS3_k127_5082411_13 - - - - 0.000000000004264 76.0
TLS3_k127_5082411_14 Cytochrome C oxidase, cbb3-type, subunit III K05301 - 1.8.2.1 0.000000000006491 78.0
TLS3_k127_5082411_15 Haemolysin-type calcium-binding repeat (2 copies) K01406,K07004 - 3.4.24.40 0.0003224 51.0
TLS3_k127_5082411_2 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 339.0
TLS3_k127_5082411_3 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 316.0
TLS3_k127_5082411_4 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000001043 278.0
TLS3_k127_5082411_5 PspA/IM30 family K03969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001317 258.0
TLS3_k127_5082411_6 HAD-superfamily hydrolase, subfamily IIB - - - 0.000000000000000000000000000000000000000000000000000001034 207.0
TLS3_k127_5082411_7 - - - - 0.0000000000000000000000000000000000000000000001473 174.0
TLS3_k127_5082411_8 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000000000000000002426 180.0
TLS3_k127_5082411_9 Belongs to the ompA family K20276 - - 0.0000000000000000000000000000000000000000003188 178.0
TLS3_k127_5104409_0 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000002212 100.0
TLS3_k127_5104409_1 Belongs to the UPF0761 family K07058 - - 0.0000000000004596 79.0
TLS3_k127_5107859_0 Dak1_2 K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 351.0
TLS3_k127_5107859_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 327.0
TLS3_k127_5107859_2 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000000000001361 208.0
TLS3_k127_5107859_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000001364 158.0
TLS3_k127_5107859_4 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000001085 91.0
TLS3_k127_5107859_5 cheY-homologous receiver domain - - - 0.000000000000000001875 98.0
TLS3_k127_5113920_0 Fumarate hydratase class II K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 546.0
TLS3_k127_5113920_1 aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 436.0
TLS3_k127_5113920_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 310.0
TLS3_k127_5113920_3 Pyridine nucleotide-disulphide oxidoreductase K21567 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003211 287.0
TLS3_k127_5113920_4 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000004079 235.0
TLS3_k127_5113920_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000004651 228.0
TLS3_k127_5113920_6 TIGRFAM iron-sulfur cluster assembly accessory protein - - - 0.000000000000000000000000000004291 126.0
TLS3_k127_5113920_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000001266 98.0
TLS3_k127_5113920_8 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000001774 80.0
TLS3_k127_5114534_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 462.0
TLS3_k127_5114534_1 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000007448 200.0
TLS3_k127_5114534_2 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.000000000000000000000000000000000000000000000003474 179.0
TLS3_k127_5114534_3 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000000001669 171.0
TLS3_k127_5161543_0 Type III restriction enzyme, res subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 617.0
TLS3_k127_5161543_1 Aldo/keto reductase family K05882 - 1.1.1.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 431.0
TLS3_k127_5161543_2 PAC2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 289.0
TLS3_k127_5161543_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000164 215.0
TLS3_k127_5161543_4 cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000001003 161.0
TLS3_k127_5161543_5 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000004432 156.0
TLS3_k127_5161543_6 protein conserved in bacteria - - - 0.000000000000000000000002978 109.0
TLS3_k127_5164761_0 PFAM NADH Ubiquinone plastoquinone (complex I) K05565 - - 9.058e-248 787.0
TLS3_k127_5164761_1 NADH ubiquinone plastoquinone K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 533.0
TLS3_k127_5164761_2 Neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 292.0
TLS3_k127_5164761_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006245 285.0
TLS3_k127_5164761_4 Cation antiporter K05569 - - 0.0000000000000000000000000000000001998 152.0
TLS3_k127_5164761_5 Na H antiporter MnhB subunit-related protein K05566 - - 0.0000000000000000000000000000001006 130.0
TLS3_k127_5164761_6 Na H antiporter subunit K05571 - - 0.0000000000000000000000000000003652 130.0
TLS3_k127_5164761_7 PFAM NADH-ubiquinone oxidoreductase chain 4L K05567 - - 0.00000000000000000000000000001071 129.0
TLS3_k127_5164761_8 Multiple resistance and pH regulation protein F K05570 - - 0.0000000000000000000000623 107.0
TLS3_k127_5164761_9 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000002669 82.0
TLS3_k127_5177025_0 Mycobacterial 4 TMS phage holin, superfamily IV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 505.0
TLS3_k127_5177025_1 Peptidase dimerisation domain K01270 - - 0.00000000000000000000000000000000000000003949 157.0
TLS3_k127_5177025_2 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000005942 155.0
TLS3_k127_5177025_3 AI-2E family transporter - - - 0.00000000000000000000000000000000001171 151.0
TLS3_k127_5177025_4 - - - - 0.0000000000000000000000000000000001271 139.0
TLS3_k127_5177025_5 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000001963 104.0
TLS3_k127_5177219_0 Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 590.0
TLS3_k127_5177219_1 Ribonuclease E/G family K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 567.0
TLS3_k127_5177219_2 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 366.0
TLS3_k127_5177219_3 Belongs to the SEDS family K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 301.0
TLS3_k127_5177219_4 rod shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000003542 152.0
TLS3_k127_5177219_5 rod shape-determining protein MreD K03571 - - 0.0000000002032 72.0
TLS3_k127_5177219_6 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000002554 60.0
TLS3_k127_5196629_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03169 - 5.99.1.2 5.024e-302 942.0
TLS3_k127_5196629_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 310.0
TLS3_k127_5196629_2 nuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000004361 222.0
TLS3_k127_5196629_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000008157 132.0
TLS3_k127_5196629_4 response regulator - - - 0.000000000000009597 78.0
TLS3_k127_5214378_0 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000296 279.0
TLS3_k127_5214378_1 Protein of unknown function (DUF2662) - - - 0.00000000000000000000000000000000000000000000000000000000004288 230.0
TLS3_k127_5214378_2 HNH nucleases - - - 0.0000000000000000000000000000000000000000000000003951 187.0
TLS3_k127_5214378_3 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000006885 195.0
TLS3_k127_5214378_4 Protein of unknown function (DUF4446) - - - 0.000000000000000000000000004076 116.0
TLS3_k127_5214378_5 glutamine synthetase, type I K01915 - 6.3.1.2 0.000000000000000000000001384 105.0
TLS3_k127_5214378_6 - - - - 0.000000000000000000004177 106.0
TLS3_k127_5214378_7 Forkhead associated domain - - - 0.00000000000000000000504 98.0
TLS3_k127_5214378_8 Peptidase_C39 like family - - - 0.00000001654 61.0
TLS3_k127_521464_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1114.0
TLS3_k127_521464_1 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 411.0
TLS3_k127_521464_10 Glutaredoxin K03676 - - 0.0000000000000000000001336 100.0
TLS3_k127_521464_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007842 393.0
TLS3_k127_521464_3 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000004501 239.0
TLS3_k127_521464_4 Rhomboid family K19225 - 3.4.21.105 0.000000000000000000000000000000000000000000000000000109 201.0
TLS3_k127_521464_5 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000001224 184.0
TLS3_k127_521464_6 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000005835 173.0
TLS3_k127_521464_7 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.000000000000000000000000000000000000006823 166.0
TLS3_k127_521464_8 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.0000000000000000000000000000000028 144.0
TLS3_k127_521464_9 Belongs to the ComB family K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.00000000000000000000000000000118 130.0
TLS3_k127_5215826_0 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 638.0
TLS3_k127_5215826_1 methyltransferase K13311,K13326,K21335 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0046983 2.1.1.234 0.0000000000000000000000000000000000000000000000000000000007536 209.0
TLS3_k127_5215826_2 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000001258 190.0
TLS3_k127_5215826_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000001851 166.0
TLS3_k127_5219258_0 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000002283 229.0
TLS3_k127_5219258_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000004424 186.0
TLS3_k127_5219258_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000004363 156.0
TLS3_k127_5219258_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000001925 96.0
TLS3_k127_5219258_4 DsrE/DsrF-like family - - - 0.0000000000000007097 87.0
TLS3_k127_5219258_5 Required for chromosome condensation and partitioning K03529 - - 0.000000000001843 68.0
TLS3_k127_5238824_0 Formiminotransferase domain K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000001587 228.0
TLS3_k127_5238824_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000006207 95.0
TLS3_k127_5258090_0 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000002406 217.0
TLS3_k127_5258090_1 LVIVD repeat - - - 0.0000000000000000000000000000000000000000000000000000002059 217.0
TLS3_k127_5258090_2 Fe-S oxidoreductase K18928 - - 0.00000000000000000000000000000000000000000000000002196 187.0
TLS3_k127_5258090_3 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.00000000002801 67.0
TLS3_k127_5264293_0 E1-E2 ATPase K01533 - 3.6.3.4 3.241e-295 925.0
TLS3_k127_5264293_1 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 340.0
TLS3_k127_5264293_2 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000000004824 195.0
TLS3_k127_5264293_3 protein conserved in bacteria K21600 - - 0.000000000000000000000000002246 115.0
TLS3_k127_5264293_4 - - - - 0.000000000006371 69.0
TLS3_k127_5273293_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 426.0
TLS3_k127_5273293_1 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 368.0
TLS3_k127_5273293_2 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 342.0
TLS3_k127_5273293_3 Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004434 286.0
TLS3_k127_5273293_4 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000002758 235.0
TLS3_k127_5273293_5 nuclear export factor GLE1 K07040 - - 0.0000000000000000000000001349 115.0
TLS3_k127_5273293_7 positive regulation of macromolecule biosynthetic process - - - 0.000000000003932 70.0
TLS3_k127_5273293_8 Daunorubicin resistance ABC transporter ATP-binding subunit K01990 - - 0.000000001916 66.0
TLS3_k127_5275795_0 carboxypeptidase - - - 0.0 1147.0
TLS3_k127_5275795_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000009141 89.0
TLS3_k127_5275795_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.0001514 48.0
TLS3_k127_5277061_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 563.0
TLS3_k127_5277061_1 Belongs to the binding-protein-dependent transport system permease family K01997,K11960 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008694 325.0
TLS3_k127_5277061_2 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.000000000000000000000000000000000000000000000000000000000000000002096 234.0
TLS3_k127_5277061_3 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000004631 208.0
TLS3_k127_5288337_0 dehydrogenase K18369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 508.0
TLS3_k127_5288337_1 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 456.0
TLS3_k127_5288337_2 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 327.0
TLS3_k127_5288337_3 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001467 262.0
TLS3_k127_5288337_4 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000001032 194.0
TLS3_k127_5288337_5 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000001035 129.0
TLS3_k127_5294273_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000744 411.0
TLS3_k127_5294273_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 344.0
TLS3_k127_5294273_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000005696 143.0
TLS3_k127_5294273_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0004082 44.0
TLS3_k127_5295016_0 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 518.0
TLS3_k127_5295016_1 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000005245 208.0
TLS3_k127_5295016_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000002039 111.0
TLS3_k127_5295016_3 - - - - 0.000000000000000001186 99.0
TLS3_k127_5295016_4 Aminoglycoside phosphotransferase - - - 0.000000001175 63.0
TLS3_k127_5309034_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 518.0
TLS3_k127_5309034_1 glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008249 444.0
TLS3_k127_5309034_2 PFAM bifunctional deaminase-reductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000136 267.0
TLS3_k127_5309034_3 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007617 266.0
TLS3_k127_5309034_4 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000007152 248.0
TLS3_k127_5309034_5 MoaE protein K21142 - 2.8.1.12 0.00000000000000000000000000000000000000000000000009057 190.0
TLS3_k127_5309034_6 - - - - 0.00000000072 70.0
TLS3_k127_532606_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 433.0
TLS3_k127_532606_1 Bacterial Peptidase A24 N-terminal domain K02654 - 3.4.23.43 0.0000000000000000000000000000000001458 149.0
TLS3_k127_532606_2 - - - - 0.000000000000000000000003184 114.0
TLS3_k127_532606_3 Cell motility and secretion Intracellular trafficking and secretion - - - 0.000000000000006874 83.0
TLS3_k127_5326872_0 LVIVD repeat - - - 7.682e-240 752.0
TLS3_k127_5326872_1 Animal haem peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 576.0
TLS3_k127_5326872_10 membrane K08972 - - 0.0000000000000001005 86.0
TLS3_k127_5326872_11 Phospholipase_D-nuclease N-terminal - - - 0.00000000000751 70.0
TLS3_k127_5326872_2 Belongs to the D-alanine--D-alanine ligase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 556.0
TLS3_k127_5326872_3 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 355.0
TLS3_k127_5326872_4 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008038 318.0
TLS3_k127_5326872_5 Putative esterase K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006884 289.0
TLS3_k127_5326872_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000005906 243.0
TLS3_k127_5326872_7 - - - - 0.0000000000000000000000000000000000000000000000003595 182.0
TLS3_k127_5326872_8 - - - - 0.0000000000000000000000000002905 120.0
TLS3_k127_5326872_9 Transcriptional regulator padr family - - - 0.00000000000000000000000002937 111.0
TLS3_k127_5366849_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 392.0
TLS3_k127_5366849_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003852 289.0
TLS3_k127_5366849_2 Arylsulfatase a K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000001901 210.0
TLS3_k127_5366849_3 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000008969 199.0
TLS3_k127_5366849_4 type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000001505 154.0
TLS3_k127_5366849_5 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000002136 157.0
TLS3_k127_5366849_6 Helix-turn-helix XRE-family like proteins K15256 - - 0.0000105 52.0
TLS3_k127_5395223_0 Glutamate-cysteine ligase family 2(GCS2) K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 341.0
TLS3_k127_5395223_1 PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000002165 137.0
TLS3_k127_5395223_2 - - - - 0.0000000000000000000000002866 109.0
TLS3_k127_5453679_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 547.0
TLS3_k127_5453679_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000001024 195.0
TLS3_k127_5453679_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000001081 150.0
TLS3_k127_5462916_0 zinc transporter K07238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005791 258.0
TLS3_k127_5462916_1 - - - - 0.0000000000000000000000000000000000000000000000000003511 197.0
TLS3_k127_5462916_2 membrane protein of uknown function UCP014873 - - - 0.000000000000000000000000000000000000000000000000002169 190.0
TLS3_k127_5469648_0 Aldehyde dehydrogenase family K00294,K13821 - 1.2.1.88,1.5.5.2 2.516e-224 723.0
TLS3_k127_5469648_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 512.0
TLS3_k127_5469648_10 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000002029 216.0
TLS3_k127_5469648_11 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000001795 223.0
TLS3_k127_5469648_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000248 158.0
TLS3_k127_5469648_13 May be required for sporulation K09762 - - 0.00000000000000000000000000000000000118 158.0
TLS3_k127_5469648_14 ECF sigma factor K03088 - - 0.00000000000000000000000000002562 124.0
TLS3_k127_5469648_15 COG0350 Methylated DNA-protein cysteine methyltransferase K00567 - 2.1.1.63 0.0000000000000000004432 103.0
TLS3_k127_5469648_16 permeases of the drug metabolite transporter (Dmt) superfamily K03298 - - 0.00000000000000128 87.0
TLS3_k127_5469648_17 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor - - - 0.0000004448 58.0
TLS3_k127_5469648_18 - - - - 0.00005007 50.0
TLS3_k127_5469648_2 Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 445.0
TLS3_k127_5469648_3 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 409.0
TLS3_k127_5469648_4 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 392.0
TLS3_k127_5469648_5 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 328.0
TLS3_k127_5469648_6 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000001381 255.0
TLS3_k127_5469648_7 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000253 250.0
TLS3_k127_5469648_8 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000001094 248.0
TLS3_k127_5469648_9 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000005437 232.0
TLS3_k127_5472656_0 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 2.05e-292 924.0
TLS3_k127_5472656_1 LVIVD repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007237 278.0
TLS3_k127_5472656_2 response to copper ion - - - 0.000000000000000000000000000000000000000000000000000000000000000001693 242.0
TLS3_k127_5472656_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000001605 158.0
TLS3_k127_5472656_4 PFAM regulatory protein LuxR - - - 0.0000000000000000000005317 97.0
TLS3_k127_5472656_5 - - - - 0.00000000000000000002127 100.0
TLS3_k127_5472656_6 Heavy-metal-associated domain K07213 - - 0.000000000002908 73.0
TLS3_k127_5489636_0 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 364.0
TLS3_k127_5507205_0 Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 1.117e-199 643.0
TLS3_k127_5507205_1 Glycolate oxidase subunit GlcD K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 322.0
TLS3_k127_5507205_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 310.0
TLS3_k127_5507205_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000003997 181.0
TLS3_k127_5507205_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000001056 169.0
TLS3_k127_5507545_0 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004501 322.0
TLS3_k127_5507545_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000004021 127.0
TLS3_k127_5507545_2 arsR family K03892 - - 0.00000000000000000000000001052 112.0
TLS3_k127_5507545_3 phosphohistidine phosphatase K03574 - 3.6.1.55 0.000005754 49.0
TLS3_k127_551275_0 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001428 250.0
TLS3_k127_551275_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000004378 214.0
TLS3_k127_551275_2 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000001159 183.0
TLS3_k127_551275_3 methyltransferase - - - 0.000000000002006 81.0
TLS3_k127_551275_4 Uroporphyrinogen-III synthase HemD K13542 - 2.1.1.107,4.2.1.75 0.000000000006585 78.0
TLS3_k127_551275_5 two-component system sensor protein - - - 0.00000000008027 65.0
TLS3_k127_551275_6 CcmB protein K02194 - - 0.0000001273 55.0
TLS3_k127_5533037_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 461.0
TLS3_k127_5533037_1 belongs to the sigma-70 factor family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 446.0
TLS3_k127_5533037_2 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 418.0
TLS3_k127_5533037_3 Fungalysin metallopeptidase (M36) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 367.0
TLS3_k127_5533037_4 Domain of unknown function (DUF1998) K06877 - - 0.0000000000000000000000000000000000000000000000007736 177.0
TLS3_k127_5533037_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000005552 127.0
TLS3_k127_5533037_6 YCII-related domain - - - 0.000000000000000000000000002447 117.0
TLS3_k127_5533037_7 YCII-related domain - - - 0.00000000000000000000004486 104.0
TLS3_k127_5540044_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 381.0
TLS3_k127_5540044_1 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 336.0
TLS3_k127_5540044_2 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006704 269.0
TLS3_k127_5540044_3 Pfam Response regulator receiver K07689 - - 0.00000000000000000000000000000000041 141.0
TLS3_k127_5540044_4 Phospholipase_D-nuclease N-terminal - - - 0.00000000000000000000000000001305 123.0
TLS3_k127_5540044_5 Virulence factor BrkB - - - 0.0003955 50.0
TLS3_k127_5547309_0 PFAM peptidase M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 334.0
TLS3_k127_5547309_1 PFAM Amidohydrolase 3 - - - 0.00000000000000000000000000000000000000000000000000004911 199.0
TLS3_k127_5548643_0 Helix-hairpin-helix motif K14162 - 2.7.7.7 8.931e-261 821.0
TLS3_k127_5548643_1 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 353.0
TLS3_k127_5548643_2 impB/mucB/samB family - - - 0.0000000000000000000000000000000000000000000000000000000000000003441 236.0
TLS3_k127_5548643_3 - - - - 0.0000000000001439 80.0
TLS3_k127_5557134_0 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 321.0
TLS3_k127_5557134_1 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000002288 261.0
TLS3_k127_5557134_2 Helix-turn-helix XRE-family like proteins - - - 0.0000000000001322 83.0
TLS3_k127_5557134_3 lysyltransferase activity K07027 - - 0.0000000000003039 85.0
TLS3_k127_5557134_4 trisaccharide binding K03556 - - 0.00000000001523 70.0
TLS3_k127_5557134_5 Transcriptional regulator K03556 - - 0.0001156 51.0
TLS3_k127_5563419_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 4.013e-294 911.0
TLS3_k127_5563419_1 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000005004 258.0
TLS3_k127_5563419_10 AbrB family transcriptional regulator K06284 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0042802,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - 0.000000000000000001146 91.0
TLS3_k127_5563419_11 Regulatory protein, FmdB - - - 0.000000000000000004077 89.0
TLS3_k127_5563419_12 Penicillin-insensitive murein endopeptidase K07261 - - 0.00000000009069 72.0
TLS3_k127_5563419_13 PFAM blue (type 1) copper domain protein - - - 0.0003019 53.0
TLS3_k127_5563419_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000006982 265.0
TLS3_k127_5563419_3 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000003256 259.0
TLS3_k127_5563419_4 Protein of unknown function (DUF2817) - - - 0.00000000000000000000000000000000000000000000001074 181.0
TLS3_k127_5563419_5 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000001003 167.0
TLS3_k127_5563419_6 cell envelope-related transcriptional attenuator - - - 0.0000000000000000000000000000000000000004608 166.0
TLS3_k127_5563419_7 Belongs to the carbohydrate kinase PfkB family - - - 0.0000000000000000000000000000000000000005137 162.0
TLS3_k127_5563419_8 GYD domain - - - 0.0000000000000000000000000006677 115.0
TLS3_k127_5563419_9 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000009833 96.0
TLS3_k127_5585092_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 392.0
TLS3_k127_5585092_1 PFAM Activator of Hsp90 ATPase 1 family protein - - - 0.000000000000000000000000000000000000002632 152.0
TLS3_k127_5585092_2 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000001001 154.0
TLS3_k127_5585092_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000006061 133.0
TLS3_k127_5614220_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 625.0
TLS3_k127_5614220_1 Uncharacterized protein family UPF0004 K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 411.0
TLS3_k127_5614220_2 IPP transferase K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000002191 201.0
TLS3_k127_5640662_0 ABC transporter, ATP-binding protein K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000007722 231.0
TLS3_k127_5640662_1 Amino acid ABC transporter, permease protein, 3-TM K02029 - - 0.0000000000000000000000000000000000000000000000000892 192.0
TLS3_k127_5640662_2 Belongs to the bacterial solute-binding protein 3 family K02030 - - 0.000000000000000000000000000000000000000000000002774 184.0
TLS3_k127_5673957_0 Histidine kinase K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008497 334.0
TLS3_k127_5673957_1 SMART PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000006765 218.0
TLS3_k127_5673957_2 Response regulator receiver K07696 - - 0.000000000000000000000000000000002176 141.0
TLS3_k127_5673957_3 Transglycosylase associated protein - - - 0.0001639 54.0
TLS3_k127_5801449_0 TIGRFAM Translation elongation factor K02355 - - 2.65e-198 638.0
TLS3_k127_5801449_1 RNA polymerase sigma factor K02405 - - 0.000000000000000000000000000000000003345 139.0
TLS3_k127_5801449_2 - - - - 0.0000000000000000001545 97.0
TLS3_k127_5801449_4 - - - - 0.0000000000000131 78.0
TLS3_k127_582232_0 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000962 408.0
TLS3_k127_582232_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004388 280.0
TLS3_k127_582232_2 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000000000000000000000003962 203.0
TLS3_k127_582232_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000002796 185.0
TLS3_k127_5917621_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 419.0
TLS3_k127_5917621_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 341.0
TLS3_k127_5917621_10 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000002178 169.0
TLS3_k127_5917621_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000005179 169.0
TLS3_k127_5917621_12 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000002912 156.0
TLS3_k127_5917621_13 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000001569 156.0
TLS3_k127_5917621_14 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.000000000000000000000000000000000001307 160.0
TLS3_k127_5917621_15 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000002747 137.0
TLS3_k127_5917621_16 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000001629 124.0
TLS3_k127_5917621_17 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000001641 120.0
TLS3_k127_5917621_18 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000008901 111.0
TLS3_k127_5917621_19 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000002964 105.0
TLS3_k127_5917621_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 304.0
TLS3_k127_5917621_20 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000001567 101.0
TLS3_k127_5917621_21 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000003525 77.0
TLS3_k127_5917621_22 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000004616 76.0
TLS3_k127_5917621_23 ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000009105 70.0
TLS3_k127_5917621_3 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 308.0
TLS3_k127_5917621_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005723 249.0
TLS3_k127_5917621_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000004023 251.0
TLS3_k127_5917621_6 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000000005416 224.0
TLS3_k127_5917621_7 Belongs to the universal ribosomal protein uS5 family K02988 - - 0.000000000000000000000000000000000000000000000000000000000000006354 230.0
TLS3_k127_5917621_8 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000001671 215.0
TLS3_k127_5917621_9 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000019 203.0
TLS3_k127_59453_0 Belongs to the ClpA ClpB family K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001415 250.0
TLS3_k127_59453_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000009544 181.0
TLS3_k127_59453_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000166 108.0
TLS3_k127_6001219_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 516.0
TLS3_k127_6001219_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 467.0
TLS3_k127_6001219_2 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000000002777 93.0
TLS3_k127_6001219_3 Ribosomal protein S20 K02968 - - 0.00000000002923 72.0
TLS3_k127_6040321_0 Succinyl-CoA ligase like flavodoxin domain - - - 0.0000000000000000000000000000000000000000000000000000001643 216.0
TLS3_k127_6040321_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000007687 137.0
TLS3_k127_6040321_2 Thioesterase superfamily K07107 - - 0.0000000000000004927 92.0
TLS3_k127_6044657_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 529.0
TLS3_k127_6044657_1 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 426.0
TLS3_k127_6044657_10 Histidine triad (Hit) protein K02503 - - 0.00000000000000000000000001052 112.0
TLS3_k127_6044657_11 Yqey-like protein K09117 - - 0.00000000000000000000000006209 115.0
TLS3_k127_6044657_12 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000004848 88.0
TLS3_k127_6044657_13 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000005988 87.0
TLS3_k127_6044657_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 404.0
TLS3_k127_6044657_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008172 279.0
TLS3_k127_6044657_4 Oligoendopeptidase f K01283,K08602 - 3.4.15.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003234 268.0
TLS3_k127_6044657_5 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000004387 248.0
TLS3_k127_6044657_6 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000000000000000001213 207.0
TLS3_k127_6044657_7 Prokaryotic diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.0000000000000000000000000000000000000000000000000005321 201.0
TLS3_k127_6044657_8 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.00000000000000000000000000000000000001139 156.0
TLS3_k127_6044657_9 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000001055 121.0
TLS3_k127_6045918_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 331.0
TLS3_k127_6045918_1 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000012 121.0
TLS3_k127_6045918_2 Cold-shock K03704 - - 0.000000000000000000007976 101.0
TLS3_k127_6045918_3 FeS assembly protein SufD K09015 GO:0008150,GO:0009605,GO:0009607,GO:0040007,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 - 0.0000000000002595 70.0
TLS3_k127_6054635_0 transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 432.0
TLS3_k127_6054635_1 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000002579 194.0
TLS3_k127_6063429_0 Belongs to the aldehyde dehydrogenase family - - - 1.458e-219 693.0
TLS3_k127_6063429_1 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 474.0
TLS3_k127_6063429_2 Rieske 2Fe-2S K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003231 282.0
TLS3_k127_6063429_3 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000003731 158.0
TLS3_k127_6063429_4 COG0346 Lactoylglutathione lyase and related lyases - - - 0.000000000000006341 83.0
TLS3_k127_6063877_0 Beta-eliminating lyase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 338.0
TLS3_k127_6063877_1 pyrroloquinoline quinone binding - - - 0.00000000000000000003869 98.0
TLS3_k127_6063877_2 PFAM L,D-transpeptidase catalytic domain - - - 0.000003836 57.0
TLS3_k127_6074190_0 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000111 235.0
TLS3_k127_6074190_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000199 235.0
TLS3_k127_6074190_2 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000512 211.0
TLS3_k127_6074190_3 Phospholipase/Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000006623 201.0
TLS3_k127_6074190_4 Belongs to the peptidase S8 family K17734 - - 0.000000000000000000000000000000000000000000000000008832 203.0
TLS3_k127_6074190_5 Cation transport protein K03498 - - 0.000009607 47.0
TLS3_k127_6084329_0 Aconitate hydratase 1 K01681 - 4.2.1.3 0.0 1168.0
TLS3_k127_6084329_1 chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 525.0
TLS3_k127_6084329_10 P-type ATPase K17686,K19597 - 3.6.3.54 0.0007077 51.0
TLS3_k127_6084329_2 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 494.0
TLS3_k127_6084329_3 Class II aldolase adducin family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 432.0
TLS3_k127_6084329_4 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 319.0
TLS3_k127_6084329_5 Predicted membrane protein (DUF2254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002618 245.0
TLS3_k127_6084329_6 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000119 207.0
TLS3_k127_6084329_7 Pfam 2OG-Fe(II) oxygenase - - - 0.000000000000000000000000000000000000000000000001156 198.0
TLS3_k127_6084329_8 - - - - 0.0000000000000000000000000304 124.0
TLS3_k127_6084329_9 epimerase dehydratase K00091 - 1.1.1.219 0.000158 45.0
TLS3_k127_6089377_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 508.0
TLS3_k127_6089377_1 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 323.0
TLS3_k127_6089377_10 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000003378 143.0
TLS3_k127_6089377_11 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000234 83.0
TLS3_k127_6089377_2 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 329.0
TLS3_k127_6089377_3 tRNA nucleotidyltransferase poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000002066 253.0
TLS3_k127_6089377_4 Aminotransferase class-V K11325 - - 0.00000000000000000000000000000000000000000000000000000000000000004588 245.0
TLS3_k127_6089377_5 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000001507 214.0
TLS3_k127_6089377_6 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000003748 208.0
TLS3_k127_6089377_7 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000004908 199.0
TLS3_k127_6089377_8 - - - - 0.0000000000000000000000000000000000000000001615 164.0
TLS3_k127_6089377_9 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000225 160.0
TLS3_k127_6096011_0 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 415.0
TLS3_k127_6096011_1 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 327.0
TLS3_k127_6096011_2 Hep Hag repeat protein K12544 GO:0005575,GO:0005623,GO:0030115,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000007826 89.0
TLS3_k127_6129125_0 Flavin containing amine oxidoreductase K00274,K03343 - 1.4.3.10,1.4.3.4 0.000000000000000000000000000000000000000000000000000002261 197.0
TLS3_k127_6129125_1 PFAM type II secretion system K12511 - - 0.0000000000000000000000000000000000000000000000001918 188.0
TLS3_k127_6129125_2 Lysine methyltransferase - - - 0.000000000000000000000000000000000000000000005978 173.0
TLS3_k127_6129125_3 Type II secretion system (T2SS), protein F K12510 - - 0.00000000000000000000000000000000000000007361 163.0
TLS3_k127_6129125_4 Domain of unknown function (DUF4328) - - - 0.000000000000000000005156 108.0
TLS3_k127_6129125_5 protein histidine kinase activity - - - 0.0000000000000000007523 98.0
TLS3_k127_6129125_6 Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000002024 59.0
TLS3_k127_6138204_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 326.0
TLS3_k127_6138204_1 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 311.0
TLS3_k127_6138204_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 319.0
TLS3_k127_6138204_3 Peptidase propeptide and YPEB domain - - - 0.000000000000000000000001886 106.0
TLS3_k127_6138204_4 ThiS family - - - 0.0000000000000000000003352 109.0
TLS3_k127_6138204_5 - - - - 0.000001435 54.0
TLS3_k127_6162245_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768,K01769 - 4.6.1.1,4.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 388.0
TLS3_k127_6162245_1 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 362.0
TLS3_k127_6162245_2 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000002504 212.0
TLS3_k127_6162245_3 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000000000000005523 190.0
TLS3_k127_6162245_4 COG2346, Truncated hemoglobins K03406,K06886 GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0019825,GO:0020012,GO:0020037,GO:0030682,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0042737,GO:0043207,GO:0044237,GO:0044248,GO:0044270,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046209,GO:0046210,GO:0046906,GO:0048037,GO:0050896,GO:0051213,GO:0051410,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:0075136,GO:0097159,GO:0098754,GO:1901363,GO:1901698,GO:2001057 - 0.000000000000000000000000000000002465 132.0
TLS3_k127_6162245_5 ATPase (P-type) K01537,K12952 - 3.6.3.8 0.000000000000000000000005064 111.0
TLS3_k127_6188936_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 472.0
TLS3_k127_6188936_2 Transmembrane anti-sigma factor - - - 0.00000000000000000008584 91.0
TLS3_k127_6188936_3 Putative zinc-finger - - - 0.0000000000001597 72.0
TLS3_k127_6188936_4 L-lysine 6-monooxygenase (NADPH-requiring) - - - 0.000000000006883 75.0
TLS3_k127_61899_0 COG COG1459 Type II secretory pathway component PulF Cell motility and secretion Intracellular trafficking and secretion K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 354.0
TLS3_k127_61899_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009551 280.0
TLS3_k127_61899_2 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000001458 192.0
TLS3_k127_61899_3 Transcriptional regulator - - - 0.0000000000003496 72.0
TLS3_k127_61899_4 Type II secretion system (T2SS), protein M K02664 - - 0.000000000005569 79.0
TLS3_k127_61899_5 PFAM Fimbrial assembly family protein K02663 - - 0.0007483 52.0
TLS3_k127_6201806_0 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 332.0
TLS3_k127_6201806_1 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001169 261.0
TLS3_k127_6201806_2 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005057 251.0
TLS3_k127_6201806_3 FeoA K03709 - - 0.00000000000000000000000000000000000000000000000000000006266 218.0
TLS3_k127_6201806_4 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000005932 133.0
TLS3_k127_6201806_5 Rieske [2Fe-2S] domain K00363 - 1.7.1.15 0.0000000000000002497 89.0
TLS3_k127_6209940_0 Domain of unknown function (DUF1727) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 447.0
TLS3_k127_6209940_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 431.0
TLS3_k127_6209940_2 Peptidase dimerisation domain K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 308.0
TLS3_k127_6209940_3 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000004604 270.0
TLS3_k127_6209940_4 CobB/CobQ-like glutamine amidotransferase domain K07009 - - 0.0000000000000000000000000000000000000000000000000000000000000001393 249.0
TLS3_k127_6209940_5 Metal-dependent phosphohydrolase, HD region - - - 0.00000000000000000000000000000000000000000000000000001237 216.0
TLS3_k127_6209940_6 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000001096 184.0
TLS3_k127_6209940_7 Hydrolase, NUDIX family - - - 0.0000000000000001344 89.0
TLS3_k127_6222702_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 385.0
TLS3_k127_6222702_1 metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 289.0
TLS3_k127_6222702_2 - - - - 0.0000000000000000000000000000000000000000000000009538 196.0
TLS3_k127_6222702_3 Domain of unknown function (DUF4349) - - - 0.00000008476 62.0
TLS3_k127_6225481_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 331.0
TLS3_k127_6225481_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000006793 267.0
TLS3_k127_6225481_2 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00007574 48.0
TLS3_k127_6230916_0 EamA-like transporter family K11939 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 358.0
TLS3_k127_6230916_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005749 248.0
TLS3_k127_6230916_2 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000002756 247.0
TLS3_k127_6230916_3 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000000000000000000000000000008974 197.0
TLS3_k127_6230916_4 - - - - 0.0000002198 55.0
TLS3_k127_6255831_0 Pyrimidine nucleoside phosphorylase C-terminal domain K00756 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 443.0
TLS3_k127_6255831_1 Belongs to the AlaDH PNT family K00259 GO:0000286,GO:0001666,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009628,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030312,GO:0036293,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0055114,GO:0070482,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 449.0
TLS3_k127_6255831_2 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 428.0
TLS3_k127_6255831_3 Peptidase dimerisation domain K01258 - 3.4.11.4 0.00000000000000000000000000000000000007914 147.0
TLS3_k127_6255831_4 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.000000000000000000000000000006323 126.0
TLS3_k127_6270531_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 385.0
TLS3_k127_6270531_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003867 264.0
TLS3_k127_6270531_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000009793 112.0
TLS3_k127_6270531_3 - - - - 0.00000000007037 64.0
TLS3_k127_6300235_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 1.318e-252 791.0
TLS3_k127_6300235_1 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007253 435.0
TLS3_k127_6300235_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000004454 205.0
TLS3_k127_6300235_3 cellulose binding - - - 0.000000000000000000000000000000000008895 147.0
TLS3_k127_6300235_4 May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation - - - 0.0000000000164 78.0
TLS3_k127_6310103_0 translation initiation factor activity K06996 - - 0.0000000000000000000000000000000000000000000001742 170.0
TLS3_k127_6310103_1 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000001668 165.0
TLS3_k127_6310103_2 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000005111 117.0
TLS3_k127_6310103_3 Transglycosylase SLT domain - - - 0.000000000000000000006908 104.0
TLS3_k127_6310103_4 domain, Protein K12678 - - 0.000000941 56.0
TLS3_k127_6310103_5 - - - - 0.00000401 56.0
TLS3_k127_6325263_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 614.0
TLS3_k127_6325263_1 RNB K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 482.0
TLS3_k127_6325263_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 422.0
TLS3_k127_6325263_3 glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 387.0
TLS3_k127_6325263_4 ATPases associated with a variety of cellular activities K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 319.0
TLS3_k127_6325263_5 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000001715 240.0
TLS3_k127_6325263_6 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000003922 183.0
TLS3_k127_6325263_7 methyltransferase - - - 0.00000000000000000000003087 108.0
TLS3_k127_6325263_8 Belongs to the UPF0235 family K09131 - - 0.0000000000008904 74.0
TLS3_k127_6326004_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 499.0
TLS3_k127_6326004_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 300.0
TLS3_k127_6326004_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 315.0
TLS3_k127_6326004_3 RecF/RecN/SMC N terminal domain K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000116 230.0
TLS3_k127_6326004_4 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000566 114.0
TLS3_k127_6326004_5 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000237 89.0
TLS3_k127_6326004_6 Belongs to the UPF0109 family K06960 - - 0.000000000003517 80.0
TLS3_k127_6326004_7 Dodecin K09165 - - 0.0000000008459 68.0
TLS3_k127_6326693_0 DNA primase, small subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 485.0
TLS3_k127_6326693_1 Binding-protein-dependent transport system inner membrane component K02029,K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009998 327.0
TLS3_k127_6326693_10 Histidine kinase - - - 0.0000007692 60.0
TLS3_k127_6326693_2 ATPases associated with a variety of cellular activities K02028,K02029 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 328.0
TLS3_k127_6326693_3 WYL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 310.0
TLS3_k127_6326693_4 Bacterial periplasmic substrate-binding proteins K02030,K02424,K17073 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001116 287.0
TLS3_k127_6326693_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000006472 234.0
TLS3_k127_6326693_6 Haemolysin-III related K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000002813 232.0
TLS3_k127_6326693_7 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000001122 203.0
TLS3_k127_6326693_8 - - - - 0.00000000000000000000000000284 114.0
TLS3_k127_6326693_9 - - - - 0.000000000000000000000003786 114.0
TLS3_k127_6327558_0 Cytochrome C and Quinol oxidase polypeptide I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 352.0
TLS3_k127_6327558_1 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002967 263.0
TLS3_k127_6327558_2 amino acid transport K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000001424 255.0
TLS3_k127_6327558_3 - - - - 0.0000000000000000000000003638 113.0
TLS3_k127_6327558_4 Cytochrome c K05301 - 1.8.2.1 0.000000000002581 72.0
TLS3_k127_6335495_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 435.0
TLS3_k127_6335495_1 Isocitrate lyase K01637 - 4.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000872 424.0
TLS3_k127_6335495_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000594 193.0
TLS3_k127_6335495_3 Sigma-70 region 2 K03091 - - 0.000000000000000000000000000000638 124.0
TLS3_k127_6335495_4 YacP-like NYN domain K06962 - - 0.00003176 53.0
TLS3_k127_6341081_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 427.0
TLS3_k127_6341081_1 Low temperature requirement A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 422.0
TLS3_k127_6341081_2 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 321.0
TLS3_k127_6341081_3 HD-GYP domain K03540 - 3.1.26.5 0.0000000000000000000000000000000000000000000000000000001435 208.0
TLS3_k127_6341081_4 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000001342 138.0
TLS3_k127_6341081_5 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000004218 120.0
TLS3_k127_6341081_6 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.9 0.0000000000000000000000005118 104.0
TLS3_k127_6348431_0 MMPL family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007173 612.0
TLS3_k127_6348431_1 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000000000000000000000000000003818 185.0
TLS3_k127_6348431_2 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000009286 184.0
TLS3_k127_6348431_3 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000002688 168.0
TLS3_k127_6348431_4 TIR domain - - - 0.000000000000000000000000000000000000000005752 170.0
TLS3_k127_6348431_5 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.00000000000000000000000000004841 118.0
TLS3_k127_6348431_6 ADP binding K08282,K13419 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.7.11.1 0.000000000000000000001276 102.0
TLS3_k127_6348431_7 efflux transmembrane transporter activity K02004 - - 0.000000000000001326 88.0
TLS3_k127_6394904_0 AAA domain, putative AbiEii toxin, Type IV TA system K02028,K09972,K10041 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 379.0
TLS3_k127_6394904_1 Binding-protein-dependent transport system inner membrane component K09970 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002416 290.0
TLS3_k127_6394904_2 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004274 299.0
TLS3_k127_6394904_3 Formate--tetrahydrofolate ligase K00288 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0017076,GO:0017144,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.5,3.5.4.9,6.3.4.3 0.0000000000000000000000000000000000000000000000000002016 190.0
TLS3_k127_6394904_4 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.00000001222 67.0
TLS3_k127_6396029_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 588.0
TLS3_k127_6396029_1 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 382.0
TLS3_k127_6396029_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000001089 269.0
TLS3_k127_6396029_3 Sigma-70 region 3 K03090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001677 257.0
TLS3_k127_6396029_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000001878 175.0
TLS3_k127_6396029_5 Cupin 2, conserved barrel domain protein K21700 - - 0.0000000000000000003141 91.0
TLS3_k127_6396029_6 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000000004457 95.0
TLS3_k127_6396029_7 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.000000000000000002048 86.0
TLS3_k127_6396029_8 Lytic transglycolase - - - 0.00000001074 62.0
TLS3_k127_6396029_9 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B) K04757 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 2.7.11.1 0.00001418 55.0
TLS3_k127_6409516_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 618.0
TLS3_k127_6409516_1 Orn Lys Arg decarboxylase K01585 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 450.0
TLS3_k127_6409516_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 449.0
TLS3_k127_6409516_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000002017 216.0
TLS3_k127_6409516_4 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000004551 150.0
TLS3_k127_6445770_0 magnesium chelatase, ChlI subunit K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 449.0
TLS3_k127_6445770_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000007108 220.0
TLS3_k127_6445770_2 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000001135 223.0
TLS3_k127_6445770_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000002226 135.0
TLS3_k127_6445770_4 Belongs to the UPF0102 family K07460 - - 0.000000000001068 80.0
TLS3_k127_6445770_5 ATP-grasp domain - - - 0.000003366 57.0
TLS3_k127_647508_0 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively - - - 0.00000000000000000000000000000000000000000000000000000000000000004092 228.0
TLS3_k127_647508_1 - - - - 0.0000000000000000000000000000597 121.0
TLS3_k127_647508_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.7.7.7 0.00000000000000001225 87.0
TLS3_k127_6514544_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 5.345e-314 990.0
TLS3_k127_6514544_1 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 9.214e-282 882.0
TLS3_k127_6514544_10 Major Facilitator Superfamily - - - 0.00002086 53.0
TLS3_k127_6514544_2 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18313 - 2.8.3.16,2.8.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 591.0
TLS3_k127_6514544_3 Required for the activity of the bacterial periplasmic transport system of putrescine K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 389.0
TLS3_k127_6514544_4 Pyruvate carboxyltransferase K01640,K18314 - 4.1.3.4,4.1.3.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 377.0
TLS3_k127_6514544_5 Protein of unknown function (DUF3891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000223 297.0
TLS3_k127_6514544_6 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000118 271.0
TLS3_k127_6514544_7 FCD - - - 0.00000000000000000000000000000000000000000000009812 179.0
TLS3_k127_6514544_8 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.00000000000000000000000000004981 127.0
TLS3_k127_6536207_0 AhpC/TSA family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 300.0
TLS3_k127_6536207_1 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003291 277.0
TLS3_k127_6536207_2 AhpC/TSA family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000003256 215.0
TLS3_k127_6536207_3 Epoxide hydrolase N terminus - - - 0.0000000000000000000000000000000000000000000000000003663 184.0
TLS3_k127_6536207_4 Cupin domain - - - 0.00000000000000000000000000000000000000008781 151.0
TLS3_k127_6552065_0 glutamine synthetase, type I K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 580.0
TLS3_k127_6552065_1 Histidine kinase K00936,K01719,K01768,K02030,K02584,K10441,K13924,K20962 - 2.1.1.80,2.7.13.3,3.1.1.61,3.1.4.52,3.6.3.17,4.2.1.75,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000005605 249.0
TLS3_k127_6892146_0 Drug exporters of the RND superfamily K06994,K07003 - - 1.006e-215 696.0
TLS3_k127_6892146_1 Belongs to the class I fructose-bisphosphate aldolase family K01623 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 451.0
TLS3_k127_6892146_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 358.0
TLS3_k127_6892146_3 6-phosphogluconolactonase activity - - - 0.000000000000000000000000000000000000000007077 167.0
TLS3_k127_6892146_5 transcriptional regulator K13643 - - 0.0000000000000009281 83.0
TLS3_k127_6892146_6 - - - - 0.00002173 48.0
TLS3_k127_6929208_0 cyclopropane-fatty-acyl-phospholipid synthase K00574,K18827 - 2.1.1.294,2.1.1.79,2.7.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 435.0
TLS3_k127_6929208_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 407.0
TLS3_k127_6929208_2 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K20444 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 332.0
TLS3_k127_6929208_3 Methyltransferase domain protein K12710,K13317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000201 284.0
TLS3_k127_6929208_4 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001517 240.0
TLS3_k127_6949479_0 peptidase U62, modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000001607 220.0
TLS3_k127_6949479_1 LVIVD repeat - - - 0.000000001392 70.0
TLS3_k127_6949479_2 LVIVD repeat - - - 0.00000001729 67.0
TLS3_k127_6949479_3 Metallo-peptidase family M12B Reprolysin-like - - - 0.0009232 51.0
TLS3_k127_7013958_0 Carboxypeptidase - - - 5.715e-304 953.0
TLS3_k127_7013958_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000005788 264.0
TLS3_k127_7013958_10 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000003568 98.0
TLS3_k127_7013958_11 Acyltransferase K00655 - 2.3.1.51 0.0007766 51.0
TLS3_k127_7013958_2 Belongs to the HAD-like hydrolase superfamily K02566 - - 0.0000000000000000000000000000000000000000000000000000000000000000002696 237.0
TLS3_k127_7013958_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000587 197.0
TLS3_k127_7013958_4 Response regulator receiver K02479 - - 0.00000000000000000000000000000000000000000002068 166.0
TLS3_k127_7013958_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000001685 164.0
TLS3_k127_7013958_6 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000002581 160.0
TLS3_k127_7013958_7 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000000000000000000001958 164.0
TLS3_k127_7013958_8 RF-1 domain K15034 - - 0.000000000000000000000002889 116.0
TLS3_k127_7013958_9 Belongs to the universal stress protein A family - - - 0.0000000000000000000000306 104.0
TLS3_k127_7047239_0 MMPL family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 574.0
TLS3_k127_7047239_1 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000000000007075 166.0
TLS3_k127_7047239_2 Lamin Tail Domain - - - 0.000000000000000000000000000000000000000003069 169.0
TLS3_k127_7047239_3 - - - - 0.0000000000000000000000000000000000001576 147.0
TLS3_k127_7047239_4 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000002135 149.0
TLS3_k127_7047239_6 cellulose binding - - - 0.0000001197 64.0
TLS3_k127_7049632_0 Phosphorylase superfamily K00772,K03784 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 301.0
TLS3_k127_7049632_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000127 164.0
TLS3_k127_7049632_2 Domain of unknown function (DUF4081) K06976 - - 0.0000000000000000000000000000001273 134.0
TLS3_k127_7049632_3 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000006037 106.0
TLS3_k127_7059161_0 56kDa selenium binding protein (SBP56) K17285 - - 1.47e-228 716.0
TLS3_k127_7059161_1 Daunorubicin resistance ABC transporter ATP-binding subunit K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 505.0
TLS3_k127_7059161_2 Drug exporters of the RND superfamily K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 438.0
TLS3_k127_7059161_3 Transport permease protein K01992,K18233 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 408.0
TLS3_k127_7059161_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001026 250.0
TLS3_k127_7059161_5 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000009086 239.0
TLS3_k127_7059161_6 - - - - 0.0000000000000000000000000000000000000000000000000000000725 205.0
TLS3_k127_7063958_0 glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 477.0
TLS3_k127_7063958_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 394.0
TLS3_k127_7063958_2 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000005165 260.0
TLS3_k127_7063958_3 - - - - 0.000000000000000000000000000000000009939 139.0
TLS3_k127_7063958_4 ORF located using Blastx - - - 0.00000000000000000000002968 101.0
TLS3_k127_7063958_5 - - - - 0.000000000000002288 78.0
TLS3_k127_7063958_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.42 0.000006437 49.0
TLS3_k127_7075311_0 EamA-like transporter family K03298 - - 0.00000000000000000000000000000000000000000000000000001565 205.0
TLS3_k127_7075311_1 FCD - - - 0.0000000000000000000000000000000000000000003838 177.0
TLS3_k127_7075311_2 glycosyl transferase family 2 K00721,K00786 - 2.4.1.83 0.00000000000000000000000007692 109.0
TLS3_k127_7075311_3 glycosyl transferase group 1 - - - 0.00000000000000138 78.0
TLS3_k127_7075420_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009661 370.0
TLS3_k127_7075420_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 361.0
TLS3_k127_7075420_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000002213 194.0
TLS3_k127_7075420_3 Protein of unknown function (DUF1211) - - - 0.00000000000000009689 89.0
TLS3_k127_7129606_0 Intein splicing domain K02469 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 0.0 1236.0
TLS3_k127_7129606_1 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.000000000000000002792 87.0
TLS3_k127_7150845_0 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 534.0
TLS3_k127_7150845_1 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000111 208.0
TLS3_k127_7150845_2 PFAM PHP domain K02347 - - 0.000000000000000000000000000000000000000000000000009 184.0
TLS3_k127_7150845_3 Proline racemase K01777 - 5.1.1.4 0.00000000000000000000000000000000000000000001002 179.0
TLS3_k127_7183701_0 Uncharacterised protein family (UPF0261) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 546.0
TLS3_k127_7183701_1 Phosphoenolpyruvate hydrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 465.0
TLS3_k127_7183701_2 FAD linked oxidases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 406.0
TLS3_k127_7183701_3 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 383.0
TLS3_k127_7183701_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 337.0
TLS3_k127_7183701_5 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 323.0
TLS3_k127_7183701_6 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000281 275.0
TLS3_k127_7183701_7 Uncharacterised protein family (UPF0261) - - - 0.00000000000000000000000000000000000000000000000000000000000000001018 244.0
TLS3_k127_7183701_8 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000007562 161.0
TLS3_k127_7183701_9 Cupin - - - 0.0000000000000000000003071 110.0
TLS3_k127_7186074_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 337.0
TLS3_k127_7186074_1 Putative glycosyl hydrolase domain - - - 0.00003464 53.0
TLS3_k127_7190704_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 487.0
TLS3_k127_7190704_1 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007948 407.0
TLS3_k127_7190704_10 - - - - 0.0000000000000005688 94.0
TLS3_k127_7190704_11 Domain of unknown function (DUF4234) - - - 0.0000000005399 66.0
TLS3_k127_7190704_12 Belongs to the universal stress protein A family - - - 0.000000009351 69.0
TLS3_k127_7190704_2 peptidase dimerisation domain K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 374.0
TLS3_k127_7190704_3 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 343.0
TLS3_k127_7190704_4 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000198 215.0
TLS3_k127_7190704_5 CoA-binding domain protein - - - 0.000000000000000000000000000000000000000000000005888 197.0
TLS3_k127_7190704_6 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000000000000000000000000000000004223 180.0
TLS3_k127_7190704_7 - - - - 0.000000000000000000000000000000000008197 157.0
TLS3_k127_7190704_8 COGs COG3367 conserved K16149 - 2.4.1.18 0.00000000000000000000000000000732 136.0
TLS3_k127_7190704_9 Protein of unknown function DUF58 - - - 0.00000000000000000001193 107.0
TLS3_k127_7215646_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 320.0
TLS3_k127_7215646_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000002084 204.0
TLS3_k127_7215646_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000003206 191.0
TLS3_k127_7230350_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 6.014e-211 676.0
TLS3_k127_7230350_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008287 516.0
TLS3_k127_7230350_2 Drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000136 128.0
TLS3_k127_7302849_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008150,GO:0008152,GO:0009295,GO:0009330,GO:0009987,GO:0016043,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.99.1.3 5.855e-240 765.0
TLS3_k127_7302849_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 605.0
TLS3_k127_7302849_2 Belongs to the UPF0232 family - - - 0.000000178 61.0
TLS3_k127_7302849_3 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00004461 47.0
TLS3_k127_7304799_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.257e-227 719.0
TLS3_k127_7304799_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 308.0
TLS3_k127_7304799_2 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000002627 252.0
TLS3_k127_7304799_3 Peptidase dimerisation domain K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000004632 233.0
TLS3_k127_7304799_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000008672 193.0
TLS3_k127_7357973_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 492.0
TLS3_k127_7357973_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008117 382.0
TLS3_k127_7357973_2 OsmC-like protein K04063 - - 0.000000000000000000000000000000000003059 159.0
TLS3_k127_7357973_3 Aminoacyl-tRNA editing domain - - - 0.00000000000000000000008093 104.0
TLS3_k127_7357973_4 Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000004013 89.0
TLS3_k127_7363363_0 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 383.0
TLS3_k127_7363363_1 Putrescine transport system permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 336.0
TLS3_k127_7363363_2 Binding-protein-dependent transport system inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000001215 211.0
TLS3_k127_7363363_3 PFAM CoA-binding domain protein - - - 0.0000000000000000000000001386 114.0
TLS3_k127_7392955_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 504.0
TLS3_k127_7392955_1 LexA DNA binding domain K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000004539 255.0
TLS3_k127_7392955_2 LVIVD repeat - - - 0.000000000000000000000000000009347 132.0
TLS3_k127_7518589_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 509.0
TLS3_k127_7518589_1 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008606 290.0
TLS3_k127_7518589_2 - - - - 0.000000000000003107 87.0
TLS3_k127_7603063_0 Isocitrate/isopropylmalate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 503.0
TLS3_k127_7603063_1 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 402.0
TLS3_k127_7603063_2 ferredoxin - - - 0.0000000000004607 81.0
TLS3_k127_7603063_3 Domain of unknown function (DUF309) K09763 - - 0.0000004142 59.0
TLS3_k127_7603063_4 - - - - 0.000001435 54.0
TLS3_k127_7605047_0 Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 338.0
TLS3_k127_7605047_1 B12 binding domain K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001504 274.0
TLS3_k127_7605047_2 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001737 277.0
TLS3_k127_7605047_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000005987 174.0
TLS3_k127_7605047_4 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000002019 125.0
TLS3_k127_7605047_5 Domain of unknown function (DUF378) - - - 0.000000000000000000002895 96.0
TLS3_k127_7613249_0 abc transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 336.0
TLS3_k127_7613249_1 Involved in multi-copper enzyme maturation, permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002561 263.0
TLS3_k127_7746910_0 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001241 259.0
TLS3_k127_7746910_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000001253 224.0
TLS3_k127_7778397_0 saccharopine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 425.0
TLS3_k127_7778397_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004352 253.0
TLS3_k127_7778397_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000002709 226.0
TLS3_k127_7778397_3 Amino acid permease K03294 - - 0.0000000000466 65.0
TLS3_k127_7778397_4 Dehydrogenase E1 component K11381 - 1.2.4.4 0.0000368 49.0
TLS3_k127_7831339_0 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 598.0
TLS3_k127_7831339_1 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004237 250.0
TLS3_k127_7841549_0 synthase K11779 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 471.0
TLS3_k127_7841549_1 Animal haem peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 405.0
TLS3_k127_7841549_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000001886 125.0
TLS3_k127_7841549_3 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.000000000000000004067 93.0
TLS3_k127_7889686_0 COG COG0371 Glycerol dehydrogenase and related enzymes Energy production and conversion K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000001836 282.0
TLS3_k127_7889686_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000002147 204.0
TLS3_k127_7889686_10 transferase - - - 0.00000000000005868 85.0
TLS3_k127_7889686_11 Phosphotransferase enzyme family - - - 0.00000002464 67.0
TLS3_k127_7889686_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000001039 200.0
TLS3_k127_7889686_3 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000421 141.0
TLS3_k127_7889686_4 Glycosyltransferase like family 2 K07011 - - 0.0000000000000000000000000000001388 143.0
TLS3_k127_7889686_5 Glycosyl transferase, family 2 K16555,K16564 - - 0.00000000000000000000000000012 131.0
TLS3_k127_7889686_6 Glycosyltransferase like family 2 - - - 0.000000000000000000000000001946 122.0
TLS3_k127_7889686_7 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000007097 126.0
TLS3_k127_7889686_8 CDP-alcohol phosphatidyltransferase - - - 0.000000000000000001161 99.0
TLS3_k127_7889686_9 deacetylase - - - 0.0000000000000003009 93.0
TLS3_k127_7892193_0 MMPL family - - - 1.682e-242 769.0
TLS3_k127_7892193_1 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 289.0
TLS3_k127_7892193_2 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000366 274.0
TLS3_k127_7892193_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005729 258.0
TLS3_k127_7892193_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000007374 233.0
TLS3_k127_7892193_5 WD40 domain protein beta Propeller K03641 - - 0.000000000000000000000000000000449 130.0
TLS3_k127_7900959_0 PFAM FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 297.0
TLS3_k127_7900959_1 Permease for cytosine/purines, uracil, thiamine, allantoin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000031 291.0
TLS3_k127_7900959_3 Phosphoglycerate mutase family K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.00000000001388 77.0
TLS3_k127_7900959_4 PASTA K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000007681 58.0
TLS3_k127_7905694_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 301.0
TLS3_k127_7905694_1 Uracil DNA glycosylase superfamily K03649 - 3.2.2.28 0.000000000000000000000000000000000000005977 156.0
TLS3_k127_7905694_2 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.0000000000007849 75.0
TLS3_k127_7909811_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 591.0
TLS3_k127_7909811_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 385.0
TLS3_k127_7909811_2 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 343.0
TLS3_k127_7909811_3 AP endonuclease family 2 K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001486 265.0
TLS3_k127_7909811_4 Hydrolase K07025 - - 0.000000000000000000001962 103.0
TLS3_k127_7909811_5 peptidoglycan catabolic process - - - 0.00000000001247 74.0
TLS3_k127_7909811_6 Peptidoglycan-binding domain 1 protein - - - 0.00001854 55.0
TLS3_k127_7912548_0 - - - - 0.0000000000000000000000000000000000000000000000000000007714 206.0
TLS3_k127_7912548_1 - - - - 0.000000000000000000000000000000002944 133.0
TLS3_k127_7912548_2 PFAM Peptidase family M23 - - - 0.0000000000000000000000000000002839 132.0
TLS3_k127_7912548_3 Phage integrase family - - - 0.000000000000000000000000000002931 135.0
TLS3_k127_7912548_4 - - - - 0.000000000000001973 86.0
TLS3_k127_7912548_5 Helix-turn-helix XRE-family like proteins - - - 0.000000000002803 71.0
TLS3_k127_7912548_7 PFAM Uncharacterised protein family UPF0150 K03088,K07110 - - 0.000000004842 61.0
TLS3_k127_7912548_8 Helix-turn-helix domain - - - 0.00005135 49.0
TLS3_k127_7912548_9 Phage derived protein Gp49-like (DUF891) - - - 0.0002569 51.0
TLS3_k127_7928055_0 DNA polymerase X K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 413.0
TLS3_k127_7928055_1 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001579 286.0
TLS3_k127_7928055_2 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000002362 140.0
TLS3_k127_7928055_3 mechanosensitive ion channel K16052,K22044 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000002035 65.0
TLS3_k127_7950058_0 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 531.0
TLS3_k127_7950058_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 525.0
TLS3_k127_7950058_2 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 435.0
TLS3_k127_7950058_3 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 314.0
TLS3_k127_7950058_4 Antibiotic biosynthesis monooxygenase - - - 0.00001308 52.0
TLS3_k127_7983709_0 Peptidase S24-like K13280 - 3.4.21.89 0.0000000000000000000000000000000001461 147.0
TLS3_k127_7983709_1 - - - - 0.00000000000000000000002402 109.0
TLS3_k127_7983709_2 belongs to the glycosyl hydrolase 13 family - - - 0.00000000009258 70.0
TLS3_k127_8001975_0 HD-GYP domain K03540 - 3.1.26.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 349.0
TLS3_k127_8001975_1 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 306.0
TLS3_k127_8001975_2 D-amino acid K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 305.0
TLS3_k127_8001975_3 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 308.0
TLS3_k127_8001975_4 - - - - 0.0000000000000001454 90.0
TLS3_k127_8001975_5 ATP-grasp domain - - - 0.000003059 53.0
TLS3_k127_8007894_0 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005729 282.0
TLS3_k127_8007894_1 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000002685 166.0
TLS3_k127_8073068_0 Cysteine synthase K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 539.0
TLS3_k127_8073068_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 452.0
TLS3_k127_8083392_0 (2R)-phospho-3-sulfolactate synthase (ComA) K08097 - 4.4.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 312.0
TLS3_k127_8083392_1 Belongs to the PAPS reductase family. CysH subfamily K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000009281 247.0
TLS3_k127_8083392_2 L( )-tartrate dehydratase subunit beta K01678,K03780 - 4.2.1.2,4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000006536 234.0
TLS3_k127_8083392_3 Catalyzes the synthesis of activated sulfate K00390,K00860,K00958,K13811 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000001882 216.0
TLS3_k127_8083392_4 sulfate adenylyltransferase K00958 - 2.7.7.4 0.000000000000000000000000000000000001982 144.0
TLS3_k127_8083392_5 TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677 - 4.2.1.2 0.000000000000000000000000000036 118.0
TLS3_k127_8084786_0 proline dehydrogenase activity K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 302.0
TLS3_k127_8084786_1 Pyridoxal-dependent decarboxylase conserved domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 317.0
TLS3_k127_8084786_2 KR domain K10780 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000201 256.0
TLS3_k127_8084786_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000002204 171.0
TLS3_k127_8084786_4 EamA-like transporter family - - - 0.0000000000000000000000000000000007035 143.0
TLS3_k127_8084786_5 HAD-superfamily hydrolase, subfamily IB, PSPase-like K08966 - 3.1.3.87 0.00000000000000000000000002241 116.0
TLS3_k127_8084786_6 - - - - 0.000000000155 67.0
TLS3_k127_8088943_0 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 417.0
TLS3_k127_8088943_1 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 406.0
TLS3_k127_8088943_2 ABC transporter (Permease) K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 338.0
TLS3_k127_8088943_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 330.0
TLS3_k127_8088943_4 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000002811 221.0
TLS3_k127_8103638_0 COG0004 Ammonia permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 616.0
TLS3_k127_8103638_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008146 511.0
TLS3_k127_8103638_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001984 266.0
TLS3_k127_8103638_3 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000008411 229.0
TLS3_k127_8103638_4 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000009175 207.0
TLS3_k127_8103638_5 Glutamine amidotransferase domain - - - 0.00000000000000001986 83.0
TLS3_k127_8134233_0 DNA helicase K03657 GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 309.0
TLS3_k127_8134233_1 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000009724 121.0
TLS3_k127_8134233_2 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000008303 93.0
TLS3_k127_8173646_0 Low temperature requirement - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 526.0
TLS3_k127_8173646_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 465.0
TLS3_k127_8173646_2 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000003377 210.0
TLS3_k127_8173646_3 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000006321 202.0
TLS3_k127_8173646_4 glycerophosphoryl diester phosphodiesterase - - - 0.0000000000000000000000000000007056 130.0
TLS3_k127_8173646_5 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000004776 119.0
TLS3_k127_8173646_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000001114 108.0
TLS3_k127_8173646_7 - - - - 0.00000007399 59.0
TLS3_k127_8202298_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 469.0
TLS3_k127_8202298_1 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 377.0
TLS3_k127_8202298_2 Oxidoreductase NAD-binding domain - - - 0.0000000000000000000000000000003075 131.0
TLS3_k127_8202298_3 ATP synthase, subunit b - - - 0.0000000001054 70.0
TLS3_k127_8205847_0 Trk-type K transport K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 501.0
TLS3_k127_8205847_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009983 353.0
TLS3_k127_8205847_2 TrkA-C domain K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003081 245.0
TLS3_k127_8205847_3 - - - - 0.0000000000000000000000000000000000000002586 162.0
TLS3_k127_8284288_0 PFAM Multicopper oxidase K06324 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 390.0
TLS3_k127_8284288_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768,K01769 - 4.6.1.1,4.6.1.2 0.000000000000000000000000000000000000000000000000000000606 205.0
TLS3_k127_8459306_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 383.0
TLS3_k127_8459306_1 I and II form the functional core of the enzyme complex. electrons originating in cytochrome C are transferred via HemE a and cu(a) to the binuclear center formed by HemE A3 and cu(B) K02275 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000629 264.0
TLS3_k127_8459306_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004738 248.0
TLS3_k127_883160_0 AI-2E family transporter - - - 0.0000000000000000000000000000000001016 151.0
TLS3_k127_883160_1 Thioredoxin K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000004239 147.0
TLS3_k127_883160_2 OsmC-like protein - - - 0.0000000000000000000000000294 118.0
TLS3_k127_883160_3 SPTR Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein K07005 - - 0.00000000000000000000000003123 113.0
TLS3_k127_883160_4 DNA-binding transcription factor activity - - - 0.0000000000000000006857 95.0
TLS3_k127_883160_5 Rhodanese Homology Domain - - - 0.00002831 57.0
TLS3_k127_886052_0 Domain of unknown function (DUF1998) K06877 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 462.0
TLS3_k127_886052_1 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000003052 252.0
TLS3_k127_886052_2 Alpha beta hydrolase - - - 0.0000000000000000000000000002478 117.0
TLS3_k127_886052_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0008150,GO:0040007 2.7.4.16 0.000000000000000000001004 104.0
TLS3_k127_904210_0 - - - - 0.00000000000000000000000000000000000000000000004965 176.0
TLS3_k127_904210_1 - - - - 0.00000000000000000000000000000000000000002266 156.0
TLS3_k127_904210_2 glyoxalase III activity - - - 0.000000000000000000001689 107.0
TLS3_k127_904210_3 domain, Protein - - - 0.00000001464 66.0
TLS3_k127_904210_4 cellulase activity K01178,K14645,K18546 - 3.2.1.3 0.00000003489 61.0
TLS3_k127_906003_0 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 381.0
TLS3_k127_906003_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000573 223.0
TLS3_k127_906003_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000002277 195.0
TLS3_k127_906003_3 Cysteine-rich secretory protein family - - - 0.00000000000004236 83.0
TLS3_k127_906003_4 Phosphoglycerate mutase K15634 - 5.4.2.12 0.00000000002387 77.0
TLS3_k127_910808_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 507.0
TLS3_k127_910808_1 menaquinone-dependent protoporphyrinogen oxidase activity K00230 - 1.3.5.3 0.0000000000000000000000000000000000006603 151.0
TLS3_k127_910808_2 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000002338 106.0
TLS3_k127_940833_0 cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008544 464.0
TLS3_k127_940833_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 414.0
TLS3_k127_940833_10 Protein of unknown function (DUF1361) - - - 0.00000000000000000000000000000000000000000001715 169.0
TLS3_k127_940833_11 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000007493 109.0
TLS3_k127_940833_12 carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.00000000000000000003423 99.0
TLS3_k127_940833_13 Thioesterase superfamily - - - 0.000000000000000001655 91.0
TLS3_k127_940833_14 Bacterial-like globin K06886 - - 0.000000000000000003462 98.0
TLS3_k127_940833_2 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004501 354.0
TLS3_k127_940833_3 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 285.0
TLS3_k127_940833_4 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000001567 249.0
TLS3_k127_940833_5 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004716 242.0
TLS3_k127_940833_6 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000004983 227.0
TLS3_k127_940833_7 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000128 213.0
TLS3_k127_940833_8 COG0346 Lactoylglutathione lyase and related lyases K07032 - - 0.000000000000000000000000000000000000000000000000002224 196.0
TLS3_k127_940833_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000002093 173.0
TLS3_k127_949573_0 pfkB family carbohydrate kinase K00882 - 2.7.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 316.0
TLS3_k127_949573_1 DNA polymerase III, epsilon subunit K02342 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000004862 236.0
TLS3_k127_949573_2 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000003201 208.0
TLS3_k127_949573_3 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000001177 212.0
TLS3_k127_949573_4 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000002282 164.0
TLS3_k127_949573_5 YCII-related domain K09780 - - 0.0000000000000000000000000000000000000009521 150.0
TLS3_k127_949573_6 bacterial (prokaryotic) histone like domain - - - 0.0000000000000000000000392 111.0
TLS3_k127_949573_7 PFAM LysM domain - - - 0.000006728 58.0
TLS3_k127_97050_0 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000000006917 214.0
TLS3_k127_97050_1 Nitrous oxidase accessory protein K07218 - - 0.00005919 56.0
TLS3_k127_97050_2 flavoprotein involved in K transport - - - 0.00006864 54.0
TLS3_k127_996724_0 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009491 533.0
TLS3_k127_996724_1 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 389.0
TLS3_k127_996724_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 374.0
TLS3_k127_996724_4 Putative inner membrane exporter, YdcZ K09936 - - 0.000000000000000000000000000000000001506 145.0
TLS3_k127_996724_5 cytochrome c biogenesis protein, transmembrane region K06196 - - 0.00000000000000000000000000000002356 141.0
TLS3_k127_996724_6 Redoxin - - - 0.0000000000000009818 83.0
TLS3_k127_996724_7 2TM domain - - - 0.000000049 60.0
TLS3_k127_996784_0 Pfam Sulfatase K01130 - 3.1.6.1 0.0 1170.0
TLS3_k127_996784_1 Major facilitator Superfamily - - - 1.486e-205 647.0
TLS3_k127_996784_2 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004173 484.0