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Overview

ID MAG04048
Name TLS3_bin.25
Sample SMP0105
Taxonomy
Kingdom Archaea
Phylum Thermoproteota
Class Nitrososphaeria
Order Nitrososphaerales
Family Nitrososphaeraceae
Genus TH1177
Species TH1177 sp025922715
Assembly information
Completeness (%) 96.63
Contamination (%) 2.29
GC content (%) 29.0
N50 (bp) 17,096
Genome size (bp) 2,922,110

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2252

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1112340_0 Arsenite-activated ATPase ArsA K01551,K13993 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 353.0
TLS3_k127_1112340_2 - - - - 0.0000000000000000001198 99.0
TLS3_k127_1124810_0 PFAM Glycosyl transferases group 1 K19002 - 2.4.1.337 0.00000000000000000000000000000000000000000000000000000002957 211.0
TLS3_k127_1124810_1 TIGRFAM methyltransferase FkbM - - - 0.000000000000000000003558 105.0
TLS3_k127_1124810_2 PFAM glycosyl transferase group 1 - - - 0.0000000001273 73.0
TLS3_k127_1124810_3 PFAM glycosyl transferase group 1 - - - 0.000000001119 70.0
TLS3_k127_1124810_4 - - - - 0.000000009908 63.0
TLS3_k127_1196694_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000002822 208.0
TLS3_k127_1196694_1 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000005495 160.0
TLS3_k127_1196694_11 YHS domain - - - 0.0001254 46.0
TLS3_k127_1196694_2 Archaeal TRASH domain - - - 0.000000000000000000000000000000000000004547 151.0
TLS3_k127_1196694_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000001642 147.0
TLS3_k127_1196694_4 - - - - 0.0000000000000000000000000000000000001933 147.0
TLS3_k127_1196694_5 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.00000000000000000000000000001379 129.0
TLS3_k127_1196694_6 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000004218 120.0
TLS3_k127_1196694_7 - - - - 0.0000000000000000000000000001258 117.0
TLS3_k127_1196694_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000001166 100.0
TLS3_k127_1227302_0 Sodium hydrogen exchanger - - - 0.0000003248 52.0
TLS3_k127_1240424_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000003585 224.0
TLS3_k127_1240424_1 resistance protein K14166 - - 0.0000000000000000000000000000000000001619 158.0
TLS3_k127_1240424_2 resistance protein K14166 - - 0.00000000000000000000001168 110.0
TLS3_k127_1240424_3 helix_turn_helix, mercury resistance - - - 0.00000000000032 81.0
TLS3_k127_1247048_0 One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light- driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation K02705 - - 6.03e-322 985.0
TLS3_k127_1247048_1 Ribulose bisphosphate carboxylase large chain K01601 - 4.1.1.39 6.03e-322 985.0
TLS3_k127_1247048_10 - - - - 0.0003987 44.0
TLS3_k127_1247048_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02112,K02114 GO:0002376,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006952,GO:0006955,GO:0008150,GO:0008270,GO:0009266,GO:0009409,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009544,GO:0009570,GO:0009579,GO:0009605,GO:0009607,GO:0009620,GO:0009628,GO:0009814,GO:0009817,GO:0010287,GO:0010319,GO:0016020,GO:0030312,GO:0031967,GO:0031975,GO:0031976,GO:0031977,GO:0031984,GO:0032991,GO:0034357,GO:0042651,GO:0043167,GO:0043169,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0045087,GO:0046872,GO:0046914,GO:0050832,GO:0050896,GO:0051704,GO:0051707,GO:0055035,GO:0071944,GO:0098542,GO:0098796,GO:0098807 3.6.3.14 8.629e-281 867.0
TLS3_k127_1247048_3 Photosystem II (PSII) is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1 D2 (PsbA PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors. D2 is needed for assembly of a stable PSII complex K02706 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0010287,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035 1.10.3.9 3.096e-221 687.0
TLS3_k127_1247048_4 ATP synthase epsilon chain K02114 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009507,GO:0009526,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009941,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0034220,GO:0034357,GO:0034641,GO:0034654,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055035,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000004068 210.0
TLS3_k127_1247048_5 Photosystem II reaction center protein Z K02724 - - 0.000000000000000000000000007398 109.0
TLS3_k127_1247048_6 - - - - 0.000000000000000000353 88.0
TLS3_k127_1247048_7 - - - - 0.000000000000000039 81.0
TLS3_k127_1247048_8 Functions as actin-binding component of the Arp2 3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks K05758 GO:0000147,GO:0000902,GO:0000904,GO:0003674,GO:0003779,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0005885,GO:0005938,GO:0006810,GO:0006897,GO:0006996,GO:0007010,GO:0007015,GO:0008064,GO:0008092,GO:0008150,GO:0009653,GO:0009888,GO:0009987,GO:0010026,GO:0010090,GO:0010638,GO:0015629,GO:0016043,GO:0016192,GO:0022607,GO:0030029,GO:0030036,GO:0030154,GO:0030479,GO:0030832,GO:0030833,GO:0030838,GO:0030863,GO:0030864,GO:0030865,GO:0030866,GO:0031334,GO:0032271,GO:0032273,GO:0032502,GO:0032535,GO:0032956,GO:0032970,GO:0032989,GO:0032991,GO:0033043,GO:0034314,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0044085,GO:0044087,GO:0044089,GO:0044396,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044464,GO:0044877,GO:0045010,GO:0048468,GO:0048518,GO:0048522,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0051015,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051493,GO:0051495,GO:0061645,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066,GO:0090558,GO:0090626,GO:0097435,GO:0098657,GO:0099568,GO:0110053,GO:1902903,GO:1902905 - 0.000006978 48.0
TLS3_k127_1260124_0 - - - - 0.000000000000000000000000000003017 124.0
TLS3_k127_1260124_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00005936 47.0
TLS3_k127_1299323_0 Winged helix-turn-helix DNA-binding - - - 0.000000000000000000000000000009522 123.0
TLS3_k127_1299323_1 - - - - 0.0000000000000001412 84.0
TLS3_k127_1305133_0 Heavy metal transport detoxification protein K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 610.0
TLS3_k127_1305133_1 Mg2 transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 382.0
TLS3_k127_1305133_2 CHRD domain - - - 0.0000000000000000000000007637 110.0
TLS3_k127_1305133_3 Archaeal TRASH domain - - - 0.000003214 49.0
TLS3_k127_1306887_0 SPTR Transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000003288 227.0
TLS3_k127_1306887_1 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000000000000000000000007285 196.0
TLS3_k127_1306887_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000002143 117.0
TLS3_k127_1306887_4 Transcriptional regulator - - - 0.00000000000001221 76.0
TLS3_k127_1306887_6 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07709 - 2.7.13.3 0.00000001081 57.0
TLS3_k127_1306887_7 Lrp/AsnC ligand binding domain - - - 0.000007034 51.0
TLS3_k127_1330581_0 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 389.0
TLS3_k127_1330581_1 Galactose oxidase, central domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 328.0
TLS3_k127_1330581_2 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000000000003916 207.0
TLS3_k127_1330581_3 pyridoxamine 5-phosphate K07005 - - 0.0000000000000000000000000000000000000000000133 166.0
TLS3_k127_1330581_4 - - - - 0.0000000000000000000175 94.0
TLS3_k127_1330581_5 Mediates influx of magnesium ions K03284 - - 0.000000000000000001107 98.0
TLS3_k127_1341160_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000351 231.0
TLS3_k127_1341160_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000001654 224.0
TLS3_k127_1341160_2 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000003762 206.0
TLS3_k127_1341160_3 Large-conductance mechanosensitive channel, MscL K03282 - - 0.00000000000000000000000000000008739 127.0
TLS3_k127_1341160_5 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000001201 94.0
TLS3_k127_1341160_6 PFAM blue (type 1) copper domain protein - - - 0.000000000000009754 76.0
TLS3_k127_1341160_7 Transcriptional regulatory protein, C terminal - - - 0.0000001056 63.0
TLS3_k127_1341160_8 Collagen triple helix repeat (20 copies) - - - 0.0000001355 62.0
TLS3_k127_1341160_9 serine-type endopeptidase activity - - - 0.0002819 51.0
TLS3_k127_1343944_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000005797 214.0
TLS3_k127_1343944_1 Protein of unknown function DUF99 K09120 - - 0.0000000000000000000000000000000000000000000000000007227 189.0
TLS3_k127_1343944_2 Dual specificity phosphatase, catalytic domain K14165 - 3.1.3.16,3.1.3.48 0.0000000000000000000000000000000000000000000002783 172.0
TLS3_k127_1343944_3 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.0000000000000000000000002155 111.0
TLS3_k127_1343944_5 Two component transcriptional regulator, winged helix family K02483,K18344 - - 0.00000000002955 69.0
TLS3_k127_1343944_6 - - - - 0.000002193 56.0
TLS3_k127_1343944_7 - - - - 0.0002061 44.0
TLS3_k127_1343944_8 PFAM Diacylglycerol kinase catalytic domain - - - 0.0006693 43.0
TLS3_k127_1347590_0 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.000000000000000000000000000000000000000000000000000000000000002923 239.0
TLS3_k127_1347590_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000001732 115.0
TLS3_k127_1347590_2 PRC-barrel domain protein - - - 0.000000000000000000000008548 107.0
TLS3_k127_1347590_3 Purple acid Phosphatase, N-terminal domain - - - 0.00000000000000008064 93.0
TLS3_k127_1347590_4 acid phosphatase activity K22390 - - 0.0000000000000007252 89.0
TLS3_k127_1354338_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 1.128e-304 944.0
TLS3_k127_1354338_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 3.365e-217 686.0
TLS3_k127_1354338_10 SnoaL-like polyketide cyclase - - - 0.000000000000000006223 89.0
TLS3_k127_1354338_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 506.0
TLS3_k127_1354338_3 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 430.0
TLS3_k127_1354338_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001652 260.0
TLS3_k127_1354338_5 NADH ubiquinone oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000002295 214.0
TLS3_k127_1354338_6 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000000000000001766 169.0
TLS3_k127_1354338_7 COG0346 Lactoylglutathione lyase and related lyases K00457 - 1.13.11.27 0.0000000000000000000000000000005391 126.0
TLS3_k127_1354338_8 Thiamine-binding protein - - - 0.0000000000000000000006067 99.0
TLS3_k127_1354338_9 DoxX-like family - - - 0.000000000000000004177 89.0
TLS3_k127_137262_0 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000007458 89.0
TLS3_k127_137262_1 - - - - 0.0001533 51.0
TLS3_k127_1407231_0 phospholipase C K01114 - 3.1.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 582.0
TLS3_k127_1409241_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.921e-276 880.0
TLS3_k127_1409241_1 Belongs to the universal stress protein A family - - - 0.00000003424 64.0
TLS3_k127_1409241_2 Belongs to the universal stress protein A family - - - 0.0003251 52.0
TLS3_k127_141281_0 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000001251 267.0
TLS3_k127_141281_1 Major Intrinsic Protein K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005936 259.0
TLS3_k127_141281_2 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000003513 188.0
TLS3_k127_141281_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000001848 183.0
TLS3_k127_146278_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 467.0
TLS3_k127_146278_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 314.0
TLS3_k127_146278_11 Cobalamin B12-binding domain protein K16955,K22491 - - 0.000004765 50.0
TLS3_k127_146278_12 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07776 - - 0.0001428 50.0
TLS3_k127_146278_2 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000005926 241.0
TLS3_k127_146278_4 ASCH domain - - - 0.0000000000000000000000000000002033 127.0
TLS3_k127_146278_6 - - - - 0.0000000000000000000000000001001 115.0
TLS3_k127_146278_8 Protein of unknown function (DUF1059) - - - 0.000000001106 61.0
TLS3_k127_1469348_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000009103 153.0
TLS3_k127_1469348_1 universal stress protein - - - 0.00006612 46.0
TLS3_k127_1498391_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family - GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016427,GO:0016428,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 308.0
TLS3_k127_1498391_1 Required for chromosome condensation and partitioning - - - 0.00000000000000000000000000000000000000001938 169.0
TLS3_k127_1498391_2 - - - - 0.00000000000000000000000000000006064 128.0
TLS3_k127_1498391_3 Protein involved in ribosomal biogenesis, contains PUA domain K07565 - - 0.0000000000000000000000000003827 120.0
TLS3_k127_1498391_6 metalloendopeptidase activity K01388,K01394,K01396,K01397,K01402,K01413,K07994,K07999,K08001,K08004,K08005 GO:0000003,GO:0000122,GO:0000302,GO:0000323,GO:0001047,GO:0001067,GO:0001101,GO:0001501,GO:0001503,GO:0001554,GO:0001649,GO:0001666,GO:0001704,GO:0001706,GO:0001775,GO:0001817,GO:0001819,GO:0001958,GO:0001959,GO:0001960,GO:0001961,GO:0001968,GO:0002009,GO:0002011,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002440,GO:0002443,GO:0002444,GO:0002446,GO:0002682,GO:0002683,GO:0002684,GO:0002697,GO:0002775,GO:0002776,GO:0002777,GO:0002778,GO:0002779,GO:0002780,GO:0002790,GO:0002791,GO:0002793,GO:0002831,GO:0003006,GO:0003416,GO:0003417,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005102,GO:0005488,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005764,GO:0005773,GO:0005783,GO:0005789,GO:0005794,GO:0005829,GO:0005911,GO:0006355,GO:0006357,GO:0006508,GO:0006518,GO:0006606,GO:0006807,GO:0006810,GO:0006886,GO:0006887,GO:0006913,GO:0006928,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006979,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007369,GO:0007492,GO:0007507,GO:0007548,GO:0007565,GO:0007567,GO:0007568,GO:0008104,GO:0008150,GO:0008152,GO:0008201,GO:0008233,GO:0008236,GO:0008237,GO:0008270,GO:0008284,GO:0008406,GO:0008585,GO:0009056,GO:0009057,GO:0009058,GO:0009605,GO:0009607,GO:0009611,GO:0009612,GO:0009615,GO:0009617,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010243,GO:0010310,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0010727,GO:0010762,GO:0010763,GO:0010941,GO:0010942,GO:0012505,GO:0014070,GO:0014910,GO:0014911,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0016192,GO:0016477,GO:0016787,GO:0017038,GO:0017171,GO:0019219,GO:0019221,GO:0019222,GO:0019538,GO:0019730,GO:0019731,GO:0019898,GO:0022411,GO:0022414,GO:0022602,GO:0022603,GO:0022617,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030054,GO:0030141,GO:0030154,GO:0030163,GO:0030198,GO:0030282,GO:0030326,GO:0030334,GO:0030335,GO:0030425,GO:0030574,GO:0031012,GO:0031090,GO:0031214,GO:0031312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031334,GO:0031347,GO:0031348,GO:0031349,GO:0031410,GO:0031667,GO:0031974,GO:0031982,GO:0031983,GO:0031984,GO:0032101,GO:0032102,GO:0032459,GO:0032461,GO:0032479,GO:0032481,GO:0032501,GO:0032502,GO:0032504,GO:0032647,GO:0032727,GO:0032879,GO:0032880,GO:0032940,GO:0032963,GO:0032991,GO:0033036,GO:0033365,GO:0033554,GO:0034097,GO:0034405,GO:0034504,GO:0034599,GO:0034613,GO:0034614,GO:0034641,GO:0034774,GO:0035107,GO:0035108,GO:0035113,GO:0035116,GO:0035137,GO:0035265,GO:0035313,GO:0035580,GO:0035690,GO:0035987,GO:0036075,GO:0036230,GO:0036293,GO:0036477,GO:0040007,GO:0040011,GO:0040012,GO:0040017,GO:0042060,GO:0042119,GO:0042127,GO:0042175,GO:0042221,GO:0042406,GO:0042475,GO:0042476,GO:0042481,GO:0042487,GO:0042493,GO:0042581,GO:0042698,GO:0042742,GO:0042886,GO:0042995,GO:0043005,GO:0043043,GO:0043062,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043171,GO:0043200,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043254,GO:0043299,GO:0043312,GO:0043565,GO:0043603,GO:0043604,GO:0043627,GO:0043900,GO:0044057,GO:0044058,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044297,GO:0044319,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044433,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0044703,GO:0044706,GO:0044849,GO:0044877,GO:0045055,GO:0045088,GO:0045089,GO:0045137,GO:0045184,GO:0045321,GO:0045824,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0046545,GO:0046581,GO:0046660,GO:0046872,GO:0046903,GO:0046907,GO:0046914,GO:0048306,GO:0048511,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048598,GO:0048608,GO:0048609,GO:0048646,GO:0048705,GO:0048729,GO:0048731,GO:0048736,GO:0048856,GO:0048869,GO:0048870,GO:0050678,GO:0050679,GO:0050688,GO:0050691,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050727,GO:0050728,GO:0050750,GO:0050776,GO:0050777,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050829,GO:0050830,GO:0050878,GO:0050896,GO:0050900,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051128,GO:0051130,GO:0051169,GO:0051170,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051193,GO:0051195,GO:0051216,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051252,GO:0051253,GO:0051254,GO:0051270,GO:0051272,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0051896,GO:0051898,GO:0060054,GO:0060135,GO:0060173,GO:0060205,GO:0060255,GO:0060338,GO:0060339,GO:0060340,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060429,GO:0060456,GO:0060759,GO:0060760,GO:0060761,GO:0061448,GO:0061458,GO:0061844,GO:0065007,GO:0065008,GO:0070011,GO:0070013,GO:0070167,GO:0070170,GO:0070173,GO:0070201,GO:0070325,GO:0070482,GO:0070727,GO:0070820,GO:0070887,GO:0071214,GO:0071229,GO:0071230,GO:0071241,GO:0071260,GO:0071310,GO:0071345,GO:0071417,GO:0071495,GO:0071496,GO:0071498,GO:0071702,GO:0071704,GO:0071705,GO:0071731,GO:0071732,GO:0071840,GO:0072359,GO:0072594,GO:0080090,GO:0080134,GO:0080135,GO:0090087,GO:0090186,GO:0090187,GO:0090504,GO:0090505,GO:0097159,GO:0097186,GO:0097366,GO:0097367,GO:0097447,GO:0097458,GO:0097708,GO:0098542,GO:0098586,GO:0098827,GO:0098868,GO:0099503,GO:0104004,GO:0120025,GO:0120038,GO:0140096,GO:1900407,GO:1900409,GO:1901163,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902531,GO:1902532,GO:1902679,GO:1902680,GO:1902739,GO:1902741,GO:1902882,GO:1902884,GO:1903201,GO:1903209,GO:1903506,GO:1903507,GO:1903508,GO:1903530,GO:1903532,GO:1904242,GO:1904244,GO:1904724,GO:1904951,GO:2000026,GO:2000027,GO:2000112,GO:2000113,GO:2000145,GO:2000147,GO:2000241,GO:2000377,GO:2000378,GO:2001141 3.4.24.17,3.4.24.22,3.4.24.23,3.4.24.34,3.4.24.65,3.4.24.7 0.00001879 54.0
TLS3_k127_1511051_0 SPTR Transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000006147 218.0
TLS3_k127_1511925_0 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000007168 221.0
TLS3_k127_1511925_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000003126 213.0
TLS3_k127_1511925_2 - - - - 0.000000000000000000000003655 112.0
TLS3_k127_1514848_0 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 528.0
TLS3_k127_1514848_1 cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 341.0
TLS3_k127_1514848_10 Tetratricopeptide repeat - - - 0.0000000000000000002346 93.0
TLS3_k127_1514848_11 PFAM Phosphoglycerate mutase K08296 - - 0.0000000000000001323 86.0
TLS3_k127_1514848_12 COG0433 Predicted ATPase - - - 0.000000000000001848 84.0
TLS3_k127_1514848_13 PFAM MscS Mechanosensitive ion channel - - - 0.0000000000001445 79.0
TLS3_k127_1514848_14 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07713,K07714,K19641 - - 0.000000000002846 72.0
TLS3_k127_1514848_15 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00002997 47.0
TLS3_k127_1514848_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 323.0
TLS3_k127_1514848_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001329 255.0
TLS3_k127_1514848_4 COG0433 Predicted ATPase - - - 0.0000000000000000000000000000000000000000000000008393 188.0
TLS3_k127_1514848_5 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000000000002705 176.0
TLS3_k127_1514848_6 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000004954 177.0
TLS3_k127_1514848_8 Ferritin Dps family protein K03594 - 1.16.3.1 0.000000000000000000000000000000003941 133.0
TLS3_k127_1514848_9 Glycosyltransferase Family 4 - - - 0.0000000000000000000001143 111.0
TLS3_k127_152033_0 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003957 242.0
TLS3_k127_1525058_0 CHRD domain - - - 0.0000000000000000000000000000002301 129.0
TLS3_k127_1525058_1 Universal stress protein - - - 0.0002416 44.0
TLS3_k127_157132_0 - - - - 0.000000000000000000000337 105.0
TLS3_k127_158072_0 Subtilase family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002089 288.0
TLS3_k127_158072_1 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000002353 212.0
TLS3_k127_160338_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000001055 252.0
TLS3_k127_160338_1 Zinc-dependent metalloprotease K07763 - 3.4.24.80 0.000007813 55.0
TLS3_k127_160461_0 Hydroxymethylglutaryl-coenzyme A synthase N terminal K01641 - 2.3.3.10 3.834e-242 754.0
TLS3_k127_160461_1 Radical SAM K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 557.0
TLS3_k127_160461_10 - - - - 0.000000000000001145 78.0
TLS3_k127_160461_2 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 530.0
TLS3_k127_160461_3 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 511.0
TLS3_k127_160461_4 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 323.0
TLS3_k127_160461_5 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000009494 256.0
TLS3_k127_160461_6 Copper resistance protein D - - - 0.000000000000000000000000000000000000000195 155.0
TLS3_k127_160461_7 - - - - 0.000000000000000000000000009257 115.0
TLS3_k127_160461_8 COG1522 Transcriptional regulators - - - 0.00000000000000000000009577 103.0
TLS3_k127_160461_9 - - - - 0.000000000000000000001468 96.0
TLS3_k127_161458_0 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001445 271.0
TLS3_k127_161458_1 Purple acid Phosphatase, N-terminal domain - - - 0.0000000000000000000004387 108.0
TLS3_k127_161458_2 acid phosphatase activity K22390 - - 0.000000000000001287 88.0
TLS3_k127_161458_3 - - - - 0.00000005474 59.0
TLS3_k127_163993_0 - - - - 0.0000000000000000000000000004696 117.0
TLS3_k127_1657969_0 DEAD DEAH box helicase K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 536.0
TLS3_k127_1657969_1 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 334.0
TLS3_k127_1657969_10 Hemolysin-type calcium-binding region - - - 0.00000000008278 70.0
TLS3_k127_1657969_2 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006727 297.0
TLS3_k127_1657969_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001146 277.0
TLS3_k127_1657969_4 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003297 260.0
TLS3_k127_1657969_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003945 260.0
TLS3_k127_1657969_6 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000001197 232.0
TLS3_k127_1657969_7 - - - - 0.000000000000000000000000000000000000004364 157.0
TLS3_k127_1657969_8 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000244 107.0
TLS3_k127_1657969_9 - - - - 0.0000000000004431 70.0
TLS3_k127_1667992_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 2145.0
TLS3_k127_1667992_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0 2023.0
TLS3_k127_1667992_10 NGG1p interacting factor 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 304.0
TLS3_k127_1667992_11 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005669 267.0
TLS3_k127_1667992_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001133 259.0
TLS3_k127_1667992_13 Participates in transcription termination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000003566 231.0
TLS3_k127_1667992_14 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) K05967 - - 0.000000000000000000000000000000000000000000000000000000000001648 214.0
TLS3_k127_1667992_15 Mn2 -dependent serine threonine protein kinase K08851 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000004895 211.0
TLS3_k127_1667992_16 Belongs to the HAM1 NTPase family K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000001501 192.0
TLS3_k127_1667992_17 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.0000000000000000000000000000000000009384 139.0
TLS3_k127_1667992_18 - - - - 0.00000000000000000000000000001092 121.0
TLS3_k127_1667992_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 562.0
TLS3_k127_1667992_20 - - - - 0.00000000000000000000004964 102.0
TLS3_k127_1667992_21 - - - - 0.0000000000000000785 85.0
TLS3_k127_1667992_22 - K03646 - - 0.0000000000000002691 80.0
TLS3_k127_1667992_23 Transcriptional regulator - - - 0.000002943 53.0
TLS3_k127_1667992_24 nuclease - - - 0.00007321 55.0
TLS3_k127_1667992_3 GTPase of unknown function C-terminal K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 542.0
TLS3_k127_1667992_4 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 531.0
TLS3_k127_1667992_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 500.0
TLS3_k127_1667992_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 449.0
TLS3_k127_1667992_7 ATPase family associated with various cellular activities (AAA) K04800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 364.0
TLS3_k127_1667992_8 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K18604 - 2.1.3.15,6.4.1.2,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 348.0
TLS3_k127_1667992_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 335.0
TLS3_k127_1700498_0 - - - - 0.00000000000000000000000000000000000000000000000002856 192.0
TLS3_k127_1700498_1 PFAM NHL repeat containing protein - - - 0.00001374 53.0
TLS3_k127_1727430_0 Type III restriction enzyme, res subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 527.0
TLS3_k127_1727430_1 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 495.0
TLS3_k127_1727430_10 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000005251 147.0
TLS3_k127_1727430_11 O-methyltransferase - - - 0.0000000000000000000000000000003856 127.0
TLS3_k127_1727430_13 Major Facilitator Superfamily - - - 0.0000000000000000000000002958 108.0
TLS3_k127_1727430_14 Universal stress protein - - - 0.0000000000000000000001067 103.0
TLS3_k127_1727430_15 Peptidase family M23 - - - 0.000000000000000000002009 100.0
TLS3_k127_1727430_17 PFAM Ammonia monooxygenase methane monooxygenase, subunit C K10946 - - 0.00000000000000001446 81.0
TLS3_k127_1727430_19 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000003442 63.0
TLS3_k127_1727430_2 ERCC4 domain K10896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009243 395.0
TLS3_k127_1727430_20 - - - - 0.00000000005372 66.0
TLS3_k127_1727430_22 Phosphate transport regulator K07220 - - 0.0000000004549 63.0
TLS3_k127_1727430_23 restriction endonuclease K07448 - - 0.000001268 55.0
TLS3_k127_1727430_24 Major Facilitator Superfamily - - - 0.00000987 48.0
TLS3_k127_1727430_25 Major Facilitator Superfamily - - - 0.0000957 46.0
TLS3_k127_1727430_26 Protein of unknown function (DUF98) K03181 - 4.1.3.40 0.0003437 49.0
TLS3_k127_1727430_3 Belongs to the MenA family. Type 1 subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000004437 239.0
TLS3_k127_1727430_4 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001776 239.0
TLS3_k127_1727430_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00034 - 1.1.1.47 0.000000000000000000000000000000000000000000000000000000000004149 217.0
TLS3_k127_1727430_6 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000012 213.0
TLS3_k127_1727430_7 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000001412 196.0
TLS3_k127_1727430_8 - - - - 0.0000000000000000000000000000000000000000000005301 171.0
TLS3_k127_1727430_9 Nodulation protein S (NodS) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000007136 156.0
TLS3_k127_1741886_0 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 450.0
TLS3_k127_1741886_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K15510,K21835 - 1.1.98.2,1.1.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 419.0
TLS3_k127_1741886_10 acid phosphatase activity K22390 - - 0.00000000000001856 84.0
TLS3_k127_1741886_13 - - - - 0.00000000016 64.0
TLS3_k127_1741886_14 photosystem II stabilization - - - 0.000000002205 69.0
TLS3_k127_1741886_15 - - - - 0.00003713 54.0
TLS3_k127_1741886_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 323.0
TLS3_k127_1741886_4 oxidation-reduction process K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000005419 169.0
TLS3_k127_1741886_9 Purple acid Phosphatase, N-terminal domain - - - 0.000000000000000001738 99.0
TLS3_k127_1755764_0 Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008144,GO:0008150,GO:0008559,GO:0015238,GO:0015399,GO:0015405,GO:0015893,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042891,GO:0042895,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902495,GO:1990195,GO:1990196,GO:1990351 - 0.00000000000000000001332 94.0
TLS3_k127_1755764_1 Collagen triple helix repeat (20 copies) - - - 0.00003018 54.0
TLS3_k127_1777681_0 40-residue YVTN family beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 327.0
TLS3_k127_1777681_1 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005681 224.0
TLS3_k127_1777681_2 - - - - 0.00000000000000000000163 102.0
TLS3_k127_1777681_3 - - - - 0.0001157 50.0
TLS3_k127_1799025_0 aconitate hydratase K01681 - 4.2.1.3 0.0 1162.0
TLS3_k127_1799025_1 resistance protein K14166 - - 4.183e-198 653.0
TLS3_k127_1799025_10 ATPase activity K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 369.0
TLS3_k127_1799025_11 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 317.0
TLS3_k127_1799025_12 cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 317.0
TLS3_k127_1799025_13 -transport system K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009663 295.0
TLS3_k127_1799025_14 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 290.0
TLS3_k127_1799025_15 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005139 277.0
TLS3_k127_1799025_16 beta-1,4-mannooligosaccharide phosphorylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001562 250.0
TLS3_k127_1799025_17 PspA/IM30 family K03969 - - 0.000000000000000000000000000000000000000000000000000000000000002769 225.0
TLS3_k127_1799025_18 MgtC family K07507 - - 0.00000000000000000000000000000000000000000000000000000000004713 207.0
TLS3_k127_1799025_19 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000005842 226.0
TLS3_k127_1799025_2 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 559.0
TLS3_k127_1799025_20 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000007951 224.0
TLS3_k127_1799025_21 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000002465 201.0
TLS3_k127_1799025_22 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000004405 185.0
TLS3_k127_1799025_23 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.000000000000000000000000001718 117.0
TLS3_k127_1799025_24 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000002839 111.0
TLS3_k127_1799025_25 zinc finger - - - 0.000000000000000000000006174 104.0
TLS3_k127_1799025_27 - - - - 0.00000000000000000000004341 107.0
TLS3_k127_1799025_28 AAA domain K07028 - - 0.0000000000000000000004285 102.0
TLS3_k127_1799025_29 response regulator, receiver - - - 0.0000000000000000000125 96.0
TLS3_k127_1799025_3 CBS domain K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 561.0
TLS3_k127_1799025_31 - - - - 0.0000000000000005986 85.0
TLS3_k127_1799025_32 Type I secretion target GGXGXDXXX repeat (2 copies) - - - 0.000000000002015 77.0
TLS3_k127_1799025_33 Conserved repeat domain - - - 0.0000000000436 72.0
TLS3_k127_1799025_34 Dodecin K09165 - - 0.000000001482 61.0
TLS3_k127_1799025_35 PFAM Protein kinase domain - - - 0.000000003364 65.0
TLS3_k127_1799025_36 poly(R)-hydroxyalkanoic acid synthase subunit PhaC K03821 - - 0.00000001055 57.0
TLS3_k127_1799025_38 Dodecin K09165 - - 0.0000006857 53.0
TLS3_k127_1799025_39 Sensory domain in DIguanylate Cyclases and Two-component system - - - 0.0001347 51.0
TLS3_k127_1799025_4 malic enzyme K00027,K00029 - 1.1.1.38,1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 533.0
TLS3_k127_1799025_40 Major Facilitator Superfamily - - - 0.0004605 44.0
TLS3_k127_1799025_5 COG1653 ABC-type sugar transport system, periplasmic component K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 504.0
TLS3_k127_1799025_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 488.0
TLS3_k127_1799025_7 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 441.0
TLS3_k127_1799025_8 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 406.0
TLS3_k127_1799025_9 Belongs to the peptidase M50B family - GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 371.0
TLS3_k127_1813681_0 Succinyl-CoA ligase like flavodoxin domain K18593 - - 7.127e-315 978.0
TLS3_k127_1813681_1 Belongs to the RtcB family K14415 - 6.5.1.3 6.243e-246 766.0
TLS3_k127_1813681_10 PFAM TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009157 260.0
TLS3_k127_1813681_11 Located on the platform of the 30S subunit K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007865 249.0
TLS3_k127_1813681_12 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000002214 253.0
TLS3_k127_1813681_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003154 243.0
TLS3_k127_1813681_14 Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity K08096 - 3.5.4.29 0.000000000000000000000000000000000000000000000000000000000000000000007241 242.0
TLS3_k127_1813681_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002161 237.0
TLS3_k127_1813681_16 RibD C-terminal domain K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000000000000000000000002116 227.0
TLS3_k127_1813681_17 Zinc finger domain - - - 0.00000000000000000000000000000000000000000000000000000000001064 218.0
TLS3_k127_1813681_18 riboflavin synthase, alpha K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000001798 209.0
TLS3_k127_1813681_19 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000002274 168.0
TLS3_k127_1813681_2 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 606.0
TLS3_k127_1813681_20 - - - - 0.0000000000000000000000000000000005072 133.0
TLS3_k127_1813681_21 - - - - 0.000000000000000000000000000000009863 131.0
TLS3_k127_1813681_22 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000002061 133.0
TLS3_k127_1813681_23 5-aminolevulinic acid synthase K00652 - 2.3.1.47 0.0000000000000000000008676 95.0
TLS3_k127_1813681_24 Transcriptional regulator - - - 0.00000000000001752 76.0
TLS3_k127_1813681_27 Matrix metallopeptidase 19 K07763,K07998 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0009987,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022411,GO:0022617,GO:0030198,GO:0031012,GO:0043062,GO:0043170,GO:0044238,GO:0044421,GO:0070011,GO:0071704,GO:0071840,GO:0140096,GO:1901564 3.4.24.80 0.0000007405 59.0
TLS3_k127_1813681_28 ligase activity K00666,K03892 - - 0.00001077 50.0
TLS3_k127_1813681_3 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 511.0
TLS3_k127_1813681_4 DEAD DEAH box helicase K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 437.0
TLS3_k127_1813681_5 phosphoglucomutase phosphomannomutase alpha beta alpha domain I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 417.0
TLS3_k127_1813681_6 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 387.0
TLS3_k127_1813681_7 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 292.0
TLS3_k127_1813681_8 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009915 272.0
TLS3_k127_1813681_9 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000005396 258.0
TLS3_k127_1877863_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0 1173.0
TLS3_k127_1877863_1 Belongs to the TPP enzyme family K00156,K00158 - 1.2.3.3,1.2.5.1 9.604e-264 825.0
TLS3_k127_1877863_10 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 398.0
TLS3_k127_1877863_11 PFAM 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001541 276.0
TLS3_k127_1877863_12 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001616 285.0
TLS3_k127_1877863_13 Belongs to the glutamate synthase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001466 255.0
TLS3_k127_1877863_14 helix_turn_helix ASNC type - - - 0.000000000000000000000000000000000000000000000000000000000000000002144 229.0
TLS3_k127_1877863_15 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000002157 220.0
TLS3_k127_1877863_16 Glutamine amidotransferase domain - - - 0.000000000000000000000000000000000000000006752 165.0
TLS3_k127_1877863_17 SPTR Transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000009663 157.0
TLS3_k127_1877863_18 Ribonuclease K03469 - 3.1.26.4 0.000000000000000000000000000000006137 132.0
TLS3_k127_1877863_19 Purple acid Phosphatase, N-terminal domain - - - 0.000000000000000000000000000001308 138.0
TLS3_k127_1877863_2 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00313 - - 7.941e-249 782.0
TLS3_k127_1877863_20 - - - - 0.00000000000000000000000000003538 120.0
TLS3_k127_1877863_22 Protein of unknown function (DUF421) - - - 0.000000000000000001912 91.0
TLS3_k127_1877863_23 SPTR Transposase, IS4 family protein - - - 0.00000000000000000506 86.0
TLS3_k127_1877863_24 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.000000000003896 71.0
TLS3_k127_1877863_25 - - - - 0.00000000001826 65.0
TLS3_k127_1877863_26 PQ loop repeat K15383 - - 0.0000000008037 64.0
TLS3_k127_1877863_27 COG2801 Transposase and inactivated derivatives - - - 0.000000000884 66.0
TLS3_k127_1877863_28 mttA/Hcf106 family K03116 - - 0.0000000294 56.0
TLS3_k127_1877863_29 GXGXG motif K22082 - 2.1.1.21 0.000001132 60.0
TLS3_k127_1877863_3 TIGRFAM glutamine synthetase, type I K01915 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.1.2 3.181e-194 618.0
TLS3_k127_1877863_30 Lrp/AsnC ligand binding domain - - - 0.00008782 48.0
TLS3_k127_1877863_31 Conserved region in glutamate synthase - - - 0.0002826 53.0
TLS3_k127_1877863_4 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 537.0
TLS3_k127_1877863_5 Electron transfer flavoprotein domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 508.0
TLS3_k127_1877863_6 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 498.0
TLS3_k127_1877863_7 Aldehyde dehydrogenase family K00135,K08324 GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006520,GO:0006525,GO:0006527,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009013,GO:0009056,GO:0009060,GO:0009063,GO:0009064,GO:0009065,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009448,GO:0009450,GO:0009987,GO:0015980,GO:0016020,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0034641,GO:0042133,GO:0042135,GO:0042402,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044464,GO:0045333,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0072329,GO:0072350,GO:0097164,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.16,1.2.1.20,1.2.1.24,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 469.0
TLS3_k127_1877863_8 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 387.0
TLS3_k127_1877863_9 ABC-type transport system, periplasmic component surface lipoprotein K02058,K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 391.0
TLS3_k127_1926188_0 multicopper - - - 0.0000000000000001791 84.0
TLS3_k127_1958299_0 Pfam:DUF217 - - - 0.0003196 46.0
TLS3_k127_2013062_0 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000008827 187.0
TLS3_k127_2013062_1 - - - - 0.0000000009533 63.0
TLS3_k127_203035_2 Transposase and inactivated derivatives K07494,K07499 - - 0.0000000000000001035 86.0
TLS3_k127_203035_3 COG3415 Transposase and inactivated derivatives K07499 - - 0.00000001375 63.0
TLS3_k127_203035_4 PFAM Integrase core domain K07497 - - 0.00000003535 57.0
TLS3_k127_203035_5 Protein of unknown function (DUF1264) - - - 0.0000003484 56.0
TLS3_k127_2099296_0 Sodium hydrogen exchanger K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009389 279.0
TLS3_k127_2099296_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000002626 98.0
TLS3_k127_2099296_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00001063 51.0
TLS3_k127_2099296_3 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.0008326 44.0
TLS3_k127_211253_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008411 281.0
TLS3_k127_211253_1 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000001629 143.0
TLS3_k127_211253_2 This gene contains a nucleotide ambiguity which may be the result of a sequencing error - - - 0.0000000000000001417 84.0
TLS3_k127_2121603_0 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008355 598.0
TLS3_k127_2121603_1 COG3547 Transposase and inactivated derivatives - - - 0.000000000000000001129 89.0
TLS3_k127_2121603_2 COG3547 Transposase and inactivated derivatives - - - 0.00003569 48.0
TLS3_k127_2127458_0 F5/8 type C domain - - - 0.0000000000000000000000000456 119.0
TLS3_k127_2127458_1 - - - - 0.000000000000000000000411 99.0
TLS3_k127_2134181_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009504 287.0
TLS3_k127_2134181_1 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000005823 198.0
TLS3_k127_2134181_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00001652 57.0
TLS3_k127_2134181_5 Transcriptional regulator - - - 0.0000171 48.0
TLS3_k127_2191471_0 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000001773 211.0
TLS3_k127_2191471_1 PFAM GCN5-related N-acetyltransferase K00619 - 2.3.1.1 0.000000000000000000000000000000005078 129.0
TLS3_k127_2191471_2 TIGRFAM phosphodiesterase, MJ0936 family K07095 - - 0.0000000000000000007824 88.0
TLS3_k127_2191471_3 peptidyl-tyrosine sulfation - - - 0.000000000000000006792 91.0
TLS3_k127_2191471_4 - - - - 0.000000000000003105 81.0
TLS3_k127_2191471_5 PFAM GCN5-related N-acetyltransferase K00619 - 2.3.1.1 0.000000000000005082 76.0
TLS3_k127_2191471_6 Transcriptional regulator - - - 0.00000000000001276 76.0
TLS3_k127_2191471_7 Acetyltransferase (GNAT) domain - - - 0.00000000000004113 72.0
TLS3_k127_2191471_9 peptidyl-tyrosine sulfation - - - 0.00002868 47.0
TLS3_k127_2207695_0 DEAD/H associated K03724 - - 0.0 1180.0
TLS3_k127_2207695_1 Thiamine biosynthesis protein (ThiI) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 474.0
TLS3_k127_2207695_3 DDE superfamily endonuclease - - - 0.000006086 52.0
TLS3_k127_2265087_1 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000003736 181.0
TLS3_k127_2314860_0 ABC-type transport system, involved in lipoprotein release, permease component K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 466.0
TLS3_k127_2314860_1 Trypsin-like serine protease with C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 374.0
TLS3_k127_2314860_10 COG2931 RTX toxins and related Ca2 -binding proteins K01406 - 3.4.24.40 0.00000000007788 72.0
TLS3_k127_2314860_11 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0001219 51.0
TLS3_k127_2314860_12 Protein tyrosine kinase - - - 0.0001615 51.0
TLS3_k127_2314860_2 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 361.0
TLS3_k127_2314860_3 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 357.0
TLS3_k127_2314860_4 ABC-type antimicrobial peptide transport system, ATPase component K02003,K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 311.0
TLS3_k127_2314860_5 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 321.0
TLS3_k127_2314860_6 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000004058 231.0
TLS3_k127_2314860_8 type I secretion target repeat protein - - - 0.00000000000000002447 89.0
TLS3_k127_2314860_9 - - - - 0.000000000001577 79.0
TLS3_k127_2346942_1 Histidine kinase - - - 0.0002294 44.0
TLS3_k127_2349694_0 Transposase DDE domain K07492 - - 0.00000000000000000000000000000000000000000000000000000000007088 208.0
TLS3_k127_2349694_1 Transposase - - - 0.0000000000000000000002097 102.0
TLS3_k127_2349694_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000004834 96.0
TLS3_k127_2349694_3 PFAM UspA domain protein - - - 0.00000000000000001685 87.0
TLS3_k127_2349694_4 PFAM peptidase C14, caspase catalytic - - - 0.00001045 51.0
TLS3_k127_2353858_0 alpha/beta hydrolase fold - - - 0.00000000000001022 82.0
TLS3_k127_2375235_0 Large family of predicted nucleotide-binding domains K06865 - - 4.911e-238 750.0
TLS3_k127_2375235_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 481.0
TLS3_k127_2375235_2 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 304.0
TLS3_k127_2375235_3 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004085 255.0
TLS3_k127_2375235_4 F5/8 type C domain - - - 0.000000000000000000000000000000000000000000004076 188.0
TLS3_k127_2375235_5 Purple acid Phosphatase, N-terminal domain - - - 0.0000000000000000000000000108 128.0
TLS3_k127_2375235_6 - - - - 0.000000000000000000000004078 108.0
TLS3_k127_2388597_0 COG1252 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 330.0
TLS3_k127_2388597_1 Protocatechuate 3,4-dioxygenase beta subunit - - - 0.00000000000000000000000003123 113.0
TLS3_k127_2388653_0 Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 567.0
TLS3_k127_2388653_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004517 257.0
TLS3_k127_245119_0 COG0733 Na -dependent transporters of the SNF family K03308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009231 338.0
TLS3_k127_245119_1 Zinc finger domain - - - 0.0000000000000000000000000000000008743 133.0
TLS3_k127_245119_2 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000002636 128.0
TLS3_k127_245119_4 PFAM UspA domain protein - - - 0.0003768 50.0
TLS3_k127_245119_5 - - - - 0.0005553 49.0
TLS3_k127_246409_0 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 591.0
TLS3_k127_246409_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665,K06883 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 434.0
TLS3_k127_246409_11 - - - - 0.000000000000000000000000000001103 125.0
TLS3_k127_246409_13 - - - - 0.000000000000000000000000001303 115.0
TLS3_k127_246409_14 - - - - 0.000000000000000000000000007216 121.0
TLS3_k127_246409_16 response regulator, receiver - - - 0.000000000000005491 79.0
TLS3_k127_246409_17 Protein tyrosine kinase - - - 0.00000000000002309 81.0
TLS3_k127_246409_18 - - - - 0.00000000000008845 77.0
TLS3_k127_246409_19 - - - - 0.000000000001988 74.0
TLS3_k127_246409_2 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 399.0
TLS3_k127_246409_3 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 314.0
TLS3_k127_246409_4 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 332.0
TLS3_k127_246409_5 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000004465 225.0
TLS3_k127_246409_6 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000002237 216.0
TLS3_k127_246409_7 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000007891 191.0
TLS3_k127_246409_8 - - - - 0.00000000000000000000000000000000000000000008265 167.0
TLS3_k127_246409_9 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000058 145.0
TLS3_k127_2478864_0 HEAT repeats K06072 - 1.14.99.29 0.0000000000000000000000000000000000000000000000003595 182.0
TLS3_k127_2478864_1 Methyltransferase type 11 - - - 0.00000000000000000000006141 110.0
TLS3_k127_2486892_0 PFAM Aldehyde dehydrogenase K00135,K18601 - 1.2.1.16,1.2.1.20,1.2.1.79 1.327e-212 668.0
TLS3_k127_2486892_1 PFAM Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 547.0
TLS3_k127_2486892_2 IMP dehydrogenase activity - - - 0.000000000009319 66.0
TLS3_k127_2486892_3 PFAM NHL repeat containing protein - - - 0.0005123 43.0
TLS3_k127_2494509_0 Belongs to the arginase family K01476 - 3.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 322.0
TLS3_k127_2503571_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 576.0
TLS3_k127_2503571_1 methanogenesis marker protein 1 K09136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 576.0
TLS3_k127_2503571_10 - - - - 0.00000000000000000000000000000001076 131.0
TLS3_k127_2503571_11 - - - - 0.000000000000000000000000008859 114.0
TLS3_k127_2503571_12 ferredoxin - - - 0.00000000000000000002653 89.0
TLS3_k127_2503571_13 - - - - 0.00000000000002145 76.0
TLS3_k127_2503571_2 Phenylalanyl-tRNA synthetase alpha subunit K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 532.0
TLS3_k127_2503571_3 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 396.0
TLS3_k127_2503571_4 ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002405 285.0
TLS3_k127_2503571_5 Phenylalanyl-tRNA synthetase beta K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004554 291.0
TLS3_k127_2503571_6 Ribosomal protein L15E K02877 - - 0.000000000000000000000000000000000000000000000000000000000000000000001993 238.0
TLS3_k127_2503571_7 PFAM TfuA domain protein, core - - - 0.00000000000000000000000000000000000000000000000000000000000004936 220.0
TLS3_k127_2503571_8 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.00000000000000000000000000000000000000000003267 167.0
TLS3_k127_2503571_9 Cytidylyltransferase-like K02201 - 2.7.7.3 0.0000000000000000000000000000000000000842 147.0
TLS3_k127_2635680_0 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 1.179e-241 763.0
TLS3_k127_2635680_2 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.000001086 50.0
TLS3_k127_2653003_0 Transcriptional regulator - - - 0.000000000000006193 77.0
TLS3_k127_2653003_1 PFAM blue (type 1) copper domain protein - - - 0.0003293 49.0
TLS3_k127_2657472_0 Helix-turn-helix of DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 413.0
TLS3_k127_2657472_1 - - - - 0.00000000116 61.0
TLS3_k127_268655_0 response regulator, receiver - - - 0.0000000000000000000000009205 108.0
TLS3_k127_268655_1 response regulator, receiver - - - 0.00000000000000000000002146 104.0
TLS3_k127_268655_2 - - - - 0.00000000000549 73.0
TLS3_k127_2695376_0 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 420.0
TLS3_k127_2695376_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 372.0
TLS3_k127_2695376_2 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000000000000000000001459 145.0
TLS3_k127_2695376_3 - - - - 0.000000000000000000000001344 111.0
TLS3_k127_2695376_4 - - - - 0.0000000000000000000001678 104.0
TLS3_k127_2695376_5 Transcriptional regulator - - - 0.0000000003247 64.0
TLS3_k127_2695376_6 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000001202 66.0
TLS3_k127_2695376_7 Integrase - - - 0.0005221 45.0
TLS3_k127_2736144_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001308 262.0
TLS3_k127_2736144_1 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000003032 186.0
TLS3_k127_2736144_2 PFAM Methyltransferase type K15256 - - 0.0000000000000000000000000000000000001003 149.0
TLS3_k127_2736144_3 - - - - 0.0000000000000000000000000000000001778 136.0
TLS3_k127_2736144_4 - - - - 0.000000000000000000000000000002044 124.0
TLS3_k127_2736144_5 CHRD domain - - - 0.000000000329 70.0
TLS3_k127_2736144_6 COG1522 Transcriptional regulators - - - 0.0000002628 55.0
TLS3_k127_2764835_0 Pfam:DUF217 - - - 0.000001952 52.0
TLS3_k127_3015400_0 - - - - 0.000000000000000000000000000000000000002258 149.0
TLS3_k127_3015400_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.0000000000000000000000614 104.0
TLS3_k127_3015400_2 Cupin 2, conserved barrel domain protein - - - 0.00000000001147 67.0
TLS3_k127_304421_0 3-isopropylmalate dehydratase, large subunit K01703 - 4.2.1.33,4.2.1.35 2.185e-236 739.0
TLS3_k127_304421_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 1.231e-202 636.0
TLS3_k127_304421_10 Methyltransferase type 11 K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 326.0
TLS3_k127_304421_11 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005234 272.0
TLS3_k127_304421_12 3-isopropylmalate dehydratase, small subunit K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000009871 245.0
TLS3_k127_304421_13 NADH ubiquinone oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000008462 215.0
TLS3_k127_304421_14 PFAM Like-Sm ribonucleoprotein, core - - - 0.0000000000000000000000000000000000000000000000000000000006181 205.0
TLS3_k127_304421_15 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000000000000228 184.0
TLS3_k127_304421_16 Phage integrase family - - - 0.00000000000000000000000000000000000000001929 167.0
TLS3_k127_304421_17 - - - - 0.0000000000000000000000000000000000006659 139.0
TLS3_k127_304421_18 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000000000000000009402 145.0
TLS3_k127_304421_19 - - - - 0.000000000000000000000000000128 123.0
TLS3_k127_304421_2 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 2.242e-198 631.0
TLS3_k127_304421_20 phosphoribosyltransferase K07101 - - 0.0000000000000000000007092 100.0
TLS3_k127_304421_22 Staphylococcal nuclease homologue - - - 0.0000002875 54.0
TLS3_k127_304421_23 COG1525 Micrococcal nuclease (thermonuclease) homologs K01174 - 3.1.31.1 0.00002068 48.0
TLS3_k127_304421_3 Amino acid kinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 587.0
TLS3_k127_304421_4 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 503.0
TLS3_k127_304421_5 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 502.0
TLS3_k127_304421_6 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 415.0
TLS3_k127_304421_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 404.0
TLS3_k127_304421_8 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 376.0
TLS3_k127_304421_9 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 364.0
TLS3_k127_3065207_0 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 372.0
TLS3_k127_3065207_1 - - - - 0.00000000000000000000000000000001652 133.0
TLS3_k127_3065207_2 COG1522 Transcriptional regulators - - - 0.00000001408 56.0
TLS3_k127_3076290_0 Radical SAM K06937 - - 0.0 1087.0
TLS3_k127_3076290_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 552.0
TLS3_k127_3076290_10 ATP corrinoid adenosyltransferase K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000005748 244.0
TLS3_k127_3076290_12 SPTR Transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000008115 220.0
TLS3_k127_3076290_13 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000002142 205.0
TLS3_k127_3076290_15 Tetrahydromethanopterin S-methyltransferase, subunit A K00577 - 2.1.1.86 0.00000000000000000000000000000000000000001977 158.0
TLS3_k127_3076290_16 Reverse transcriptase-like K03469 - 3.1.26.4 0.00000000000000000000000000000000000000002974 159.0
TLS3_k127_3076290_17 - - - - 0.000000000000000000000000000000000000002577 150.0
TLS3_k127_3076290_18 - - - - 0.000000000000000000000000007014 115.0
TLS3_k127_3076290_19 - - - - 0.000000000000000000000001389 104.0
TLS3_k127_3076290_2 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 506.0
TLS3_k127_3076290_21 glycosyl transferase family 2 - - - 0.0000000000000000000006775 106.0
TLS3_k127_3076290_22 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000001341 94.0
TLS3_k127_3076290_23 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000000003782 73.0
TLS3_k127_3076290_26 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0000000002613 61.0
TLS3_k127_3076290_28 Right handed beta helix region - - - 0.00000009281 63.0
TLS3_k127_3076290_3 Belongs to the enoyl-CoA hydratase isomerase family K01715,K15019 - 4.2.1.116,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 424.0
TLS3_k127_3076290_4 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 380.0
TLS3_k127_3076290_5 Translation initiation factor 2, alpha subunit K03237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 348.0
TLS3_k127_3076290_6 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 338.0
TLS3_k127_3076290_7 Conserved hypothetical ATP binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 316.0
TLS3_k127_3076290_9 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008181 317.0
TLS3_k127_3080945_0 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000001092 230.0
TLS3_k127_3080945_1 ester cyclase - - - 0.000000000000000000000000000000000000000000000006349 178.0
TLS3_k127_3080945_2 - - - - 0.00000000000000000000000002904 113.0
TLS3_k127_3080945_3 - - - - 0.00000002794 61.0
TLS3_k127_3080945_4 Protein of unknown function DUF72 - - - 0.00002578 47.0
TLS3_k127_3080945_5 Transcriptional regulator - - - 0.0002065 44.0
TLS3_k127_3080945_6 - - - - 0.0004156 47.0
TLS3_k127_3102262_0 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 313.0
TLS3_k127_3102262_1 CBS domain - - - 0.000000000000000000000000000004044 125.0
TLS3_k127_3102262_2 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000005432 90.0
TLS3_k127_3102262_3 PFAM CBS domain containing protein - - - 0.00000000000005816 78.0
TLS3_k127_3116153_0 Cytochrome oxidase assembly protein K02259 - - 0.00000000000000000000000000007331 121.0
TLS3_k127_3116153_1 Haem utilisation ChuX/HutX - - - 0.000000000001756 72.0
TLS3_k127_3116317_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01581,K01586,K13747 - 4.1.1.17,4.1.1.20,4.1.1.96 3.631e-200 632.0
TLS3_k127_3116317_1 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 305.0
TLS3_k127_3116317_2 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000007506 227.0
TLS3_k127_3116317_4 Rieske 2Fe-2S K05710 - - 0.0000000000000000000000000000000000000000005403 158.0
TLS3_k127_3116317_5 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000006119 104.0
TLS3_k127_3116317_6 - - - - 0.000000000000000007751 87.0
TLS3_k127_3116317_7 DUF167 K09131 - - 0.000000000001625 69.0
TLS3_k127_3118977_0 DNA polymerase K02319 - 2.7.7.7 0.0 1195.0
TLS3_k127_3118977_1 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 604.0
TLS3_k127_3118977_10 hydrolase (HAD superfamily) K01091,K01560,K01561,K07025 - 3.1.3.18,3.8.1.2,3.8.1.3 0.000000000000000000000000000000000000000000000000000000001119 208.0
TLS3_k127_3118977_11 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000000000000000000000000000000000000000000000006356 204.0
TLS3_k127_3118977_12 Ribbon-helix-helix protein, copG family K07722 - - 0.00000000000000000000000000000000000000000001999 165.0
TLS3_k127_3118977_13 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000005722 172.0
TLS3_k127_3118977_14 DNA binding - - - 0.0000000000000000000000000000000000000008632 148.0
TLS3_k127_3118977_15 Domain of unknown function (DUF2024) - - - 0.00000000000000000000000000000000000000141 148.0
TLS3_k127_3118977_16 - - - - 0.0000000000000000000000000000000000001872 143.0
TLS3_k127_3118977_17 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000001186 145.0
TLS3_k127_3118977_18 Chondroitinase B - - - 0.0000000000000000000000000000000001184 153.0
TLS3_k127_3118977_19 - - - - 0.000000000000000000000000000001773 126.0
TLS3_k127_3118977_2 Domain of unknown function (DUF1297) K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 514.0
TLS3_k127_3118977_20 mttA/Hcf106 family K03116 - - 0.000000000000000000000000001893 114.0
TLS3_k127_3118977_21 - - - - 0.00000000000000000000000003407 111.0
TLS3_k127_3118977_22 Belongs to the UPF0147 family K09721 - - 0.00000000000000000000000145 105.0
TLS3_k127_3118977_24 DNA polymerase K02347 - - 0.000000000000002746 83.0
TLS3_k127_3118977_25 Concanavalin A-like lectin/glucanases superfamily - - - 0.00000000004655 76.0
TLS3_k127_3118977_26 - - - - 0.00009106 46.0
TLS3_k127_3118977_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 484.0
TLS3_k127_3118977_4 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 345.0
TLS3_k127_3118977_5 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 305.0
TLS3_k127_3118977_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001993 284.0
TLS3_k127_3118977_8 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000004045 251.0
TLS3_k127_3118977_9 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000006728 241.0
TLS3_k127_3119131_0 poly(R)-hydroxyalkanoic acid synthase K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001269 265.0
TLS3_k127_3119131_1 40-residue YVTN family beta-propeller - - - 0.0000000000000000000000000000000000000226 153.0
TLS3_k127_3119131_2 PFAM Aminotransferase class I and II K00817,K04720 - 2.6.1.9,4.1.1.81 0.00000000000000000000000000000000004687 138.0
TLS3_k127_3119131_3 40-residue YVTN family beta-propeller - - - 0.0000000000000000000004685 99.0
TLS3_k127_3119131_4 40-residue YVTN family beta-propeller - - - 0.00000000000000000000564 98.0
TLS3_k127_3119131_5 ATP-independent chaperone mediated protein folding - - - 0.00000000008871 64.0
TLS3_k127_3321000_0 Mechanosensitive ion channel - - - 0.000000000000000000000004384 115.0
TLS3_k127_3321000_1 PUB domain, zinc finger protein Thioredoxin. Source PGD - - - 0.0000000006554 65.0
TLS3_k127_345053_0 - - - - 0.000000000000000000000000000000000000000000008439 174.0
TLS3_k127_345053_1 Q COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000002936 66.0
TLS3_k127_345053_2 Matrix metallopeptidase 19 K07763,K07998 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0009987,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022411,GO:0022617,GO:0030198,GO:0031012,GO:0043062,GO:0043170,GO:0044238,GO:0044421,GO:0070011,GO:0071704,GO:0071840,GO:0140096,GO:1901564 3.4.24.80 0.00000009066 61.0
TLS3_k127_345053_3 Bacterial Ig-like domain 2 - - - 0.0000005735 60.0
TLS3_k127_345053_4 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00005047 47.0
TLS3_k127_34803_0 Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a K00148 - 1.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 530.0
TLS3_k127_34803_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 441.0
TLS3_k127_34803_10 NAD(P)H-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002387 257.0
TLS3_k127_34803_11 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000005065 249.0
TLS3_k127_34803_12 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003325 241.0
TLS3_k127_34803_13 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000228 250.0
TLS3_k127_34803_14 NAD(P)H-dependent FMN reductase K00299 - 1.5.1.38 0.0000000000000000000000000000000000000000000000000000000000000000001201 235.0
TLS3_k127_34803_15 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000176 238.0
TLS3_k127_34803_16 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000001022 236.0
TLS3_k127_34803_17 COG1651 Protein-disulfide isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000007784 224.0
TLS3_k127_34803_18 COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000009016 218.0
TLS3_k127_34803_19 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K15510,K21835 - 1.1.98.2,1.1.98.5 0.0000000000000000000000000000000000000000000000000000000001658 215.0
TLS3_k127_34803_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 399.0
TLS3_k127_34803_20 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000007744 211.0
TLS3_k127_34803_21 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000001499 192.0
TLS3_k127_34803_22 - - - - 0.00000000000000000000000000000000000000000000000003051 182.0
TLS3_k127_34803_23 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000005274 198.0
TLS3_k127_34803_24 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000001339 160.0
TLS3_k127_34803_25 Antibiotic biosynthesis monooxygenase K09932 - - 0.0000000000000000000000000000000000000002613 154.0
TLS3_k127_34803_26 - - - - 0.00000000000000000000000000000000000007309 145.0
TLS3_k127_34803_27 Thioredoxin K03671 - - 0.0000000000000000000000000000000000004065 143.0
TLS3_k127_34803_28 Pyridoxamine 5'-phosphate - - - 0.0000000000000000000000000000000000147 139.0
TLS3_k127_34803_29 Pyridoxamine 5'-phosphate - - - 0.00000000000000000000000000000002673 130.0
TLS3_k127_34803_3 Trypsin-like serine protease with C-terminal PDZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 373.0
TLS3_k127_34803_30 - - - - 0.0000000000000000000000000000000538 126.0
TLS3_k127_34803_32 R3H domain K19036 - 3.6.4.12,3.6.4.13 0.000000000000000000000000000001139 136.0
TLS3_k127_34803_33 Sodium hydrogen exchanger K03455 - - 0.000000000000000000000000000002156 123.0
TLS3_k127_34803_35 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.00000000000000000000000003488 112.0
TLS3_k127_34803_36 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000008204 113.0
TLS3_k127_34803_37 protein conserved in bacteria - - - 0.00000000000000000000003389 106.0
TLS3_k127_34803_38 GYD domain - - - 0.000000000000000000001751 97.0
TLS3_k127_34803_39 Staphylococcal nuclease homologue - - - 0.00000000000000000009854 94.0
TLS3_k127_34803_4 Lactonase, 7-bladed beta-propeller K07404 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 340.0
TLS3_k127_34803_40 Methyltransferase domain K00598 - 2.1.1.144 0.000000000000000001378 89.0
TLS3_k127_34803_41 Transcriptional regulator K07332 - - 0.00000000000000006195 90.0
TLS3_k127_34803_42 - - - - 0.00000000000000244 81.0
TLS3_k127_34803_44 Transcriptional regulator - - - 0.00000000000005891 75.0
TLS3_k127_34803_45 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000001446 66.0
TLS3_k127_34803_46 His Kinase A (phosphoacceptor) domain - - - 0.0000000001416 67.0
TLS3_k127_34803_49 PFAM blue (type 1) copper domain protein - - - 0.0000000114 57.0
TLS3_k127_34803_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03635,K03637 - 2.8.1.12,4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 316.0
TLS3_k127_34803_50 Methyltransferase domain K00598 - 2.1.1.144 0.00000001421 61.0
TLS3_k127_34803_51 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000001848 56.0
TLS3_k127_34803_52 Universal stress protein - - - 0.0000249 54.0
TLS3_k127_34803_53 Protein of unknown function (DUF559) - - - 0.00002525 55.0
TLS3_k127_34803_54 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0001834 50.0
TLS3_k127_34803_55 Luciferase-like monooxygenase - - - 0.0002999 44.0
TLS3_k127_34803_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 297.0
TLS3_k127_34803_7 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 295.0
TLS3_k127_34803_8 Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002345 276.0
TLS3_k127_34803_9 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009103 259.0
TLS3_k127_3498693_0 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008786 273.0
TLS3_k127_3498693_1 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000001585 199.0
TLS3_k127_3498693_3 Transcriptional regulator - - - 0.0000000000006915 71.0
TLS3_k127_3498693_4 Transcriptional regulator K02483 - - 0.000000000001119 74.0
TLS3_k127_3498693_5 response regulator, receiver - - - 0.00000000004025 69.0
TLS3_k127_3498693_6 PFAM Protein kinase domain - - - 0.0000000001482 70.0
TLS3_k127_3498693_7 integrase family - - - 0.000000000379 63.0
TLS3_k127_3498693_8 Psort location Cytoplasmic, score 9.97 - - - 0.0000003369 62.0
TLS3_k127_3506331_0 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000003521 155.0
TLS3_k127_3522558_0 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 456.0
TLS3_k127_3522558_1 cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 390.0
TLS3_k127_3522558_12 Alpha beta hydrolase - - - 0.000000000001491 78.0
TLS3_k127_3522558_13 COG3316 Transposase and inactivated derivatives - - - 0.00001494 50.0
TLS3_k127_3522558_15 with the alpha beta hydrolase fold - - - 0.0005698 52.0
TLS3_k127_3522558_2 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002021 287.0
TLS3_k127_3522558_3 COG0433 Predicted ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004935 265.0
TLS3_k127_3522558_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000002195 157.0
TLS3_k127_3522558_5 Purple acid Phosphatase, N-terminal domain - - - 0.00000000000000000000000001572 123.0
TLS3_k127_3522558_6 - - - - 0.0000000000000000000000002128 110.0
TLS3_k127_3522558_9 - - - - 0.000000000000000000000007892 113.0
TLS3_k127_3557121_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000002246 181.0
TLS3_k127_3557121_1 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000008887 140.0
TLS3_k127_3557121_2 catechol 1,2-dioxygenase - - - 0.0000000000000000000000000000002966 131.0
TLS3_k127_3557121_3 COG1252 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000000000000000004308 104.0
TLS3_k127_3557121_5 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000409 95.0
TLS3_k127_3557121_6 COG1252 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000001171 64.0
TLS3_k127_3567813_0 - - - - 0.0000000000000000000000000000000000001453 146.0
TLS3_k127_3567813_1 - - - - 0.000000000000000000000001604 110.0
TLS3_k127_3567813_2 Metal-dependent hydrolase K07043 - - 0.0000000000000000000000552 104.0
TLS3_k127_3567813_4 Protein of unknown function DUF45 K07043 - - 0.0000002806 56.0
TLS3_k127_3567813_5 - - - - 0.0002798 45.0
TLS3_k127_3567813_6 KAP P-loop domain protein - - - 0.0003284 46.0
TLS3_k127_3576062_0 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 293.0
TLS3_k127_3576062_1 Belongs to the MCM family K10726 - - 0.0000000000000000000000000000000000000001652 160.0
TLS3_k127_3576062_2 Iron-binding zinc finger CDGSH type K05710 - - 0.00000000000000000002236 92.0
TLS3_k127_3591690_0 AhpC/TSA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 436.0
TLS3_k127_3591690_1 Pirin C-terminal cupin domain K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 390.0
TLS3_k127_3591690_10 HTH domain - - - 0.000007923 49.0
TLS3_k127_3591690_12 Alcohol dehydrogenase zinc-binding domain protein K00344,K07119 - 1.6.5.5 0.00008874 46.0
TLS3_k127_3591690_2 cytochrome c biogenesis protein K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 352.0
TLS3_k127_3591690_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 349.0
TLS3_k127_3591690_4 Antibiotic biosynthesis monooxygenase K09932 - - 0.000000000000000000000000000000000000000000000001298 182.0
TLS3_k127_3591690_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000001955 158.0
TLS3_k127_3591690_6 Transcriptional regulator - - - 0.0000000000000000000000000000000002829 134.0
TLS3_k127_3591690_7 Bacterial regulatory protein, arsR family - - - 0.00000000000000000000000000000003042 127.0
TLS3_k127_3591690_8 - - - - 0.00000000000000000000000391 105.0
TLS3_k127_3591690_9 Putative lumazine-binding - - - 0.0000000000000002905 79.0
TLS3_k127_3593871_0 - - - - 0.00000000000000000000000000000000000000000001764 173.0
TLS3_k127_3593871_1 Universal stress protein - - - 0.000000000000000000000000000000003781 133.0
TLS3_k127_3593871_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000003885 112.0
TLS3_k127_3593871_3 Universal stress protein - - - 0.00000000000000000001379 98.0
TLS3_k127_3644717_0 NAD-dependent epimerase dehydratase K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 421.0
TLS3_k127_3644717_1 Cobalamin B12-binding domain protein K16955,K22491 - - 0.0000000000000006047 81.0
TLS3_k127_3686878_0 - - - - 0.00000000000000000000000000000000000000000000000000000000004791 222.0
TLS3_k127_3686878_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000004975 212.0
TLS3_k127_3717606_0 Purple acid Phosphatase, N-terminal domain - - - 0.0000000000000000000000000000008385 134.0
TLS3_k127_3717606_1 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.00000001026 57.0
TLS3_k127_3729578_0 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001584 257.0
TLS3_k127_3729578_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000008281 70.0
TLS3_k127_3741491_0 flavodoxin nitric oxide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 402.0
TLS3_k127_3741491_1 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000005899 242.0
TLS3_k127_3741491_2 CHRD domain - - - 0.000000000000000000000000022 114.0
TLS3_k127_3741491_3 - - - - 0.0001796 50.0
TLS3_k127_3741491_4 - - - - 0.000394 49.0
TLS3_k127_3761894_0 Catalyzes the synthesis of activated sulfate K00860,K07028 - 2.7.1.25 0.0000000000000000000000000000000000000000000000000000000003262 207.0
TLS3_k127_3761894_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000031 171.0
TLS3_k127_3761894_2 Methyltransferase FkbM domain - - - 0.00000000000000004245 93.0
TLS3_k127_3761894_3 carbohydrate metabolic process - - - 0.000000000005935 76.0
TLS3_k127_412795_0 Lactonase, 7-bladed beta-propeller K07404 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 334.0
TLS3_k127_412795_1 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000000000000000000000000000000000003859 231.0
TLS3_k127_4150775_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1294.0
TLS3_k127_4150775_1 Succinyl-CoA ligase like flavodoxin domain K18594 - - 0.0 1076.0
TLS3_k127_4150775_10 TIGRFAM glucosamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 - 2.6.1.16 3.565e-227 717.0
TLS3_k127_4150775_100 mttA/Hcf106 family K03116 - - 0.0000000009616 64.0
TLS3_k127_4150775_102 Belongs to the P(II) protein family K04751 - - 0.000000001312 64.0
TLS3_k127_4150775_106 Protein tyrosine kinase - - - 0.000003613 56.0
TLS3_k127_4150775_107 - - - - 0.000005885 53.0
TLS3_k127_4150775_11 von Willebrand factor (vWF) type A domain - - - 5.192e-225 708.0
TLS3_k127_4150775_12 High-affinity Fe2 Pb2 permease K07243 - - 8.05e-223 716.0
TLS3_k127_4150775_13 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 6.004e-213 667.0
TLS3_k127_4150775_14 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 9.186e-213 687.0
TLS3_k127_4150775_15 Peptidase family M3 K08602 - - 8.429e-211 671.0
TLS3_k127_4150775_16 magnesium chelatase K03405 - 6.6.1.1 3.075e-208 661.0
TLS3_k127_4150775_17 Fumarase C C-terminus K01744 - 4.3.1.1 1.333e-207 655.0
TLS3_k127_4150775_18 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 4.825e-205 642.0
TLS3_k127_4150775_19 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 605.0
TLS3_k127_4150775_2 DEAD DEAH box helicase K06877 - - 1.185e-292 921.0
TLS3_k127_4150775_20 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 589.0
TLS3_k127_4150775_21 DNA primase K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 566.0
TLS3_k127_4150775_22 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 506.0
TLS3_k127_4150775_23 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 522.0
TLS3_k127_4150775_24 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 496.0
TLS3_k127_4150775_25 MiaB-like tRNA modifying enzyme K15865 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 483.0
TLS3_k127_4150775_26 Diphthamide biosynthesis K07561 - 2.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 471.0
TLS3_k127_4150775_27 Mannosyl-3-phosphoglycerate synthase K05947 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.217 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008619 454.0
TLS3_k127_4150775_28 antibiotic catabolic process K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 440.0
TLS3_k127_4150775_29 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 423.0
TLS3_k127_4150775_3 RNase L inhibitor, RLI K06174 - - 2.196e-287 894.0
TLS3_k127_4150775_30 ATPase family associated with various cellular activities (AAA) K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 402.0
TLS3_k127_4150775_31 PP-loop family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 399.0
TLS3_k127_4150775_32 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 394.0
TLS3_k127_4150775_33 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008985 375.0
TLS3_k127_4150775_34 PFAM S-layer - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 375.0
TLS3_k127_4150775_35 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 372.0
TLS3_k127_4150775_36 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 364.0
TLS3_k127_4150775_37 Belongs to the UPF0284 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 371.0
TLS3_k127_4150775_38 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 346.0
TLS3_k127_4150775_39 Archaeal transcriptional regulator TrmB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 347.0
TLS3_k127_4150775_4 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 - 6.1.1.3 3.667e-271 847.0
TLS3_k127_4150775_40 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 337.0
TLS3_k127_4150775_41 Transketolase K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009452 329.0
TLS3_k127_4150775_42 transferase activity, transferring glycosyl groups K00752 - 2.4.1.212 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009948 333.0
TLS3_k127_4150775_43 Met-10+ like-protein K15429 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 321.0
TLS3_k127_4150775_44 Carbon-nitrogen hydrolase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 300.0
TLS3_k127_4150775_45 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 298.0
TLS3_k127_4150775_46 Pterin binding enzyme K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 292.0
TLS3_k127_4150775_47 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 285.0
TLS3_k127_4150775_48 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 282.0
TLS3_k127_4150775_49 Belongs to the carbohydrate kinase PfkB family K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006029 282.0
TLS3_k127_4150775_5 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 2.371e-263 819.0
TLS3_k127_4150775_50 Domain of unknown function DUF120 K07732 - 2.7.1.161 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003155 273.0
TLS3_k127_4150775_51 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008701 271.0
TLS3_k127_4150775_52 Cytidylyltransferase-like K00980,K14656 - 2.7.7.2,2.7.7.39 0.000000000000000000000000000000000000000000000000000000000000000000000000004951 258.0
TLS3_k127_4150775_53 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000000000000000000000001557 253.0
TLS3_k127_4150775_54 Chlorophyllase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000009334 259.0
TLS3_k127_4150775_55 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000009733 243.0
TLS3_k127_4150775_56 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX K17759 - 5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000002731 242.0
TLS3_k127_4150775_57 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.00000000000000000000000000000000000000000000000000000000000000003387 232.0
TLS3_k127_4150775_59 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000000000001248 224.0
TLS3_k127_4150775_6 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 1.762e-250 779.0
TLS3_k127_4150775_60 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000002727 224.0
TLS3_k127_4150775_61 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000001353 216.0
TLS3_k127_4150775_62 Binds to the 23S rRNA K02885 - - 0.00000000000000000000000000000000000000000000000000000000000183 211.0
TLS3_k127_4150775_63 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000000000000005909 205.0
TLS3_k127_4150775_64 Iron-sulfur cluster assembly accessory protein K13628 - - 0.00000000000000000000000000000000000000000000000000000008691 196.0
TLS3_k127_4150775_65 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000000000008774 198.0
TLS3_k127_4150775_66 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000004454 193.0
TLS3_k127_4150775_67 ribosomal protein K02912 - - 0.00000000000000000000000000000000000000000000000000001308 192.0
TLS3_k127_4150775_68 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000005255 201.0
TLS3_k127_4150775_69 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000001141 200.0
TLS3_k127_4150775_7 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.124e-242 758.0
TLS3_k127_4150775_70 Translin family K07477 - - 0.0000000000000000000000000000000000000000000000000001925 192.0
TLS3_k127_4150775_71 A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products - - - 0.0000000000000000000000000000000000000000000001758 173.0
TLS3_k127_4150775_72 - - - - 0.0000000000000000000000000000000000000001164 158.0
TLS3_k127_4150775_73 - - - - 0.000000000000000000000000000000000000007573 149.0
TLS3_k127_4150775_74 - - - - 0.0000000000000000000000000000000000003327 149.0
TLS3_k127_4150775_75 protein conserved in archaea K09723 - - 0.0000000000000000000000000000000000004458 146.0
TLS3_k127_4150775_76 - - - - 0.00000000000000000000000000000000000186 148.0
TLS3_k127_4150775_77 Protein of unknown function DUF126 K09128 - - 0.0000000000000000000000000000000004021 135.0
TLS3_k127_4150775_78 Transposase DDE domain K07492 - - 0.000000000000000000000000000000004329 134.0
TLS3_k127_4150775_79 Belongs to the ribosomal protein L31e family K02910 - - 0.00000000000000000000000000000009481 126.0
TLS3_k127_4150775_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 - - 3.767e-241 749.0
TLS3_k127_4150775_80 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000003512 128.0
TLS3_k127_4150775_82 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000004446 106.0
TLS3_k127_4150775_83 - - - - 0.0000000000000000000000007918 104.0
TLS3_k127_4150775_84 - - - - 0.0000000000000000000003454 98.0
TLS3_k127_4150775_85 acid phosphatase activity K22390 GO:0000003,GO:0003674,GO:0003824,GO:0003993,GO:0004721,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005615,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005829,GO:0005911,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007275,GO:0008150,GO:0008152,GO:0008199,GO:0008270,GO:0009267,GO:0009505,GO:0009506,GO:0009605,GO:0009791,GO:0009845,GO:0009846,GO:0009856,GO:0009987,GO:0009991,GO:0016036,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0022414,GO:0030054,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032501,GO:0032502,GO:0033554,GO:0036211,GO:0042578,GO:0042592,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044706,GO:0046872,GO:0046914,GO:0048856,GO:0048878,GO:0050801,GO:0050896,GO:0051704,GO:0051716,GO:0055044,GO:0055062,GO:0055081,GO:0055083,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071944,GO:0072505,GO:0072506,GO:0090351,GO:0098771,GO:0140096,GO:1901564 - 0.000000000000000000007975 104.0
TLS3_k127_4150775_86 - - - - 0.000000000000000000008836 93.0
TLS3_k127_4150775_87 - - - - 0.00000000000000000002889 93.0
TLS3_k127_4150775_88 serine-type endopeptidase activity - - - 0.0000000000000000000497 96.0
TLS3_k127_4150775_89 This gene contains a nucleotide ambiguity which may be the result of a sequencing error - - - 0.0000000000000000001889 92.0
TLS3_k127_4150775_9 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.401e-240 749.0
TLS3_k127_4150775_90 Belongs to the eukaryotic ribosomal protein eL39 family K02924 - - 0.0000000000000000007781 86.0
TLS3_k127_4150775_91 Transcriptional regulator K03718 - - 0.0000000000000000105 89.0
TLS3_k127_4150775_92 snRNP Sm proteins K04796 - - 0.0000000000000000634 82.0
TLS3_k127_4150775_93 transcriptional regulators - - - 0.0000000000000002306 82.0
TLS3_k127_4150775_94 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000007514 82.0
TLS3_k127_4150775_96 - - - - 0.0000000000001418 72.0
TLS3_k127_4150775_98 - - - - 0.00000000001531 74.0
TLS3_k127_4150775_99 zinc finger - - - 0.00000000005044 64.0
TLS3_k127_432125_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 2.994e-206 648.0
TLS3_k127_432125_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K01953,K06927 - 6.3.1.14,6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 553.0
TLS3_k127_432125_10 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006464,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0046483,GO:0051604,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000008726 53.0
TLS3_k127_432125_2 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 439.0
TLS3_k127_432125_3 COG1335 Amidases related to nicotinamidase K09020 - 3.5.1.110 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 299.0
TLS3_k127_432125_4 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003351 258.0
TLS3_k127_432125_5 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009589 252.0
TLS3_k127_432125_6 F5/8 type C domain - - - 0.0000000000000000000000000000000000000000000000000000000000008644 224.0
TLS3_k127_432125_7 RNA binding K07581 - - 0.0000000000000000002299 94.0
TLS3_k127_432125_8 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000002133 87.0
TLS3_k127_434068_0 FAD linked - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 502.0
TLS3_k127_434068_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 300.0
TLS3_k127_440971_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 368.0
TLS3_k127_440971_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000001912 136.0
TLS3_k127_440971_2 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0000000000000000000000000000000004916 145.0
TLS3_k127_440971_3 Major Facilitator Superfamily - - - 0.000000000000000000001682 96.0
TLS3_k127_440971_4 Major facilitator superfamily - - - 0.0000000001064 64.0
TLS3_k127_440971_5 Major Facilitator Superfamily - - - 0.0000007485 55.0
TLS3_k127_440993_0 Tellurite resistance protein TehB - - - 0.000002799 53.0
TLS3_k127_4489607_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1215.0
TLS3_k127_4489607_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1149.0
TLS3_k127_4489607_10 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001242 232.0
TLS3_k127_4489607_11 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000000001254 173.0
TLS3_k127_4489607_12 HD domain K07023 - - 0.00000000000000000000000000000000000000003048 158.0
TLS3_k127_4489607_13 - - - - 0.0000000000000000000000000000000000000001626 152.0
TLS3_k127_4489607_14 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.000000000000000000000000000000000000007168 149.0
TLS3_k127_4489607_15 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.000000000000000001549 88.0
TLS3_k127_4489607_17 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000003193 64.0
TLS3_k127_4489607_18 COG3316 Transposase and inactivated derivatives - - - 0.0000004049 57.0
TLS3_k127_4489607_19 SPTR Transposase, IS4 family protein - - - 0.000006514 53.0
TLS3_k127_4489607_2 LOR SDH bifunctional - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 606.0
TLS3_k127_4489607_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 601.0
TLS3_k127_4489607_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 594.0
TLS3_k127_4489607_5 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 573.0
TLS3_k127_4489607_6 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 499.0
TLS3_k127_4489607_7 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 419.0
TLS3_k127_4489607_8 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 405.0
TLS3_k127_4489607_9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 413.0
TLS3_k127_4521430_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 608.0
TLS3_k127_4521430_1 TIGRFAM precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit K03399 - 2.1.1.289 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 344.0
TLS3_k127_4521430_2 protein (ATP-grasp superfamily) K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008272 273.0
TLS3_k127_4521430_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000005181 239.0
TLS3_k127_4521430_4 Transcriptional regulator - - - 0.00000000000000005094 83.0
TLS3_k127_4533869_0 Pyridoxamine 5'-phosphate - - - 0.00000000000000000000000000000000000000000000000000005273 191.0
TLS3_k127_4533869_1 Domain of unknown function DUF87 K06915 - - 0.000000000000000000000000000000000000001358 151.0
TLS3_k127_4568487_0 SMC proteins Flexible Hinge Domain K03529 - - 1.302e-286 919.0
TLS3_k127_4568487_1 Vinylacetyl-CoA Delta-isomerase K14534 - 4.2.1.120,5.3.3.3 2.339e-280 867.0
TLS3_k127_4568487_10 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 298.0
TLS3_k127_4568487_11 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 286.0
TLS3_k127_4568487_12 phosphoribosylglycinamide formyltransferase K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000003412 260.0
TLS3_k127_4568487_13 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000006188 242.0
TLS3_k127_4568487_14 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000004449 226.0
TLS3_k127_4568487_15 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001094 233.0
TLS3_k127_4568487_16 Transcriptional regulator K07108 - - 0.000000000000000000000000000000000000000000000000000000006302 200.0
TLS3_k127_4568487_17 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000006546 150.0
TLS3_k127_4568487_18 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000004215 117.0
TLS3_k127_4568487_19 - - - - 0.00000000000000000000001162 104.0
TLS3_k127_4568487_2 Luciferase-like monooxygenase K14728 - - 2.247e-212 662.0
TLS3_k127_4568487_20 - - - - 0.0000000000000000009377 89.0
TLS3_k127_4568487_22 Iron/zinc purple acid phosphatase-like protein C K22390 - - 0.0000000000000000391 94.0
TLS3_k127_4568487_23 - - - - 0.000000000000001057 79.0
TLS3_k127_4568487_24 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0006046 45.0
TLS3_k127_4568487_3 HELICc2 - - - 1.549e-210 668.0
TLS3_k127_4568487_4 phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 537.0
TLS3_k127_4568487_5 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 441.0
TLS3_k127_4568487_6 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009543 362.0
TLS3_k127_4568487_7 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 356.0
TLS3_k127_4568487_8 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 330.0
TLS3_k127_4568487_9 Cob(II)yrinic acid a,c-diamide reductase K04719 - 1.13.11.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 315.0
TLS3_k127_4576365_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 6.456e-211 666.0
TLS3_k127_4576365_1 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000002277 221.0
TLS3_k127_4576365_2 AAA domain K07028 - - 0.0000000000000000000007142 101.0
TLS3_k127_4576365_3 PFAM CBS domain containing protein - - - 0.000000000000000000001523 100.0
TLS3_k127_4576365_4 Universal stress protein - - - 0.000000000007814 65.0
TLS3_k127_461609_0 cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 319.0
TLS3_k127_461609_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.0000000000000000000000000001754 120.0
TLS3_k127_461609_2 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000007237 99.0
TLS3_k127_461609_3 ORF located using - - - 0.0000000000000006705 88.0
TLS3_k127_461609_4 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000002641 61.0
TLS3_k127_4616578_0 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 436.0
TLS3_k127_4616578_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 367.0
TLS3_k127_4616578_10 FAD dependent oxidoreductase - - - 0.00000002248 56.0
TLS3_k127_4616578_12 - - - - 0.00001929 51.0
TLS3_k127_4616578_2 cytochrome P450 K00493,K21201 - 1.11.1.7,1.14.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 356.0
TLS3_k127_4616578_3 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K05710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 334.0
TLS3_k127_4616578_4 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001429 270.0
TLS3_k127_4616578_5 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000002197 220.0
TLS3_k127_4616578_6 COG0474 Cation transport ATPase K01537 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000001297 215.0
TLS3_k127_4616578_7 Universal stress protein - - - 0.00000000000000000000000006148 114.0
TLS3_k127_4616578_8 PFAM blue (type 1) copper domain protein - - - 0.000000000000001346 88.0
TLS3_k127_4616578_9 - - - - 0.000000000000007149 81.0
TLS3_k127_463807_0 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000004579 218.0
TLS3_k127_463807_1 Required for chromosome condensation and partitioning - - - 0.0000000000748 74.0
TLS3_k127_4639897_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01870 - 6.1.1.5 0.0 1352.0
TLS3_k127_4639897_1 Enoyl-(Acyl carrier protein) reductase - - - 1.039e-243 768.0
TLS3_k127_4639897_10 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000007329 93.0
TLS3_k127_4639897_2 Heme copper-type cytochrome quinol K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 608.0
TLS3_k127_4639897_3 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 318.0
TLS3_k127_4639897_4 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 308.0
TLS3_k127_4639897_5 transcriptional - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 314.0
TLS3_k127_4639897_6 protein (ATP-grasp superfamily) K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008034 254.0
TLS3_k127_4639897_7 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000000000000000000000000000003684 194.0
TLS3_k127_4639897_8 conserved protein implicated in secretion - - - 0.0000000000000000000000000000000002473 141.0
TLS3_k127_4639897_9 - - - - 0.000000000000000000006626 99.0
TLS3_k127_478050_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0 1004.0
TLS3_k127_478050_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.069e-255 793.0
TLS3_k127_478050_10 ATP-grasp domain K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 494.0
TLS3_k127_478050_11 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006229 475.0
TLS3_k127_478050_12 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 465.0
TLS3_k127_478050_13 Tetrapyrrole (Corrin/Porphyrin) Methylases K05934 - 2.1.1.131 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 458.0
TLS3_k127_478050_14 Cobalamin synthesis G C-terminus K02189 - 3.7.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 421.0
TLS3_k127_478050_15 COG0530 Ca2 Na antiporter K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 392.0
TLS3_k127_478050_16 Tetrapyrrole (Corrin/Porphyrin) Methylases K05936 - 2.1.1.133,2.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008207 383.0
TLS3_k127_478050_17 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 376.0
TLS3_k127_478050_18 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 361.0
TLS3_k127_478050_19 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 354.0
TLS3_k127_478050_2 Cytochrome b subunit of the bc complex K00412 - - 7.991e-249 776.0
TLS3_k127_478050_20 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 331.0
TLS3_k127_478050_21 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 293.0
TLS3_k127_478050_22 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 288.0
TLS3_k127_478050_23 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 285.0
TLS3_k127_478050_24 Cobalt chelatase (CbiK) K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 286.0
TLS3_k127_478050_25 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004412 271.0
TLS3_k127_478050_26 Circadian clock protein KaiC K06945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002144 276.0
TLS3_k127_478050_27 Tetrapyrrole (Corrin/Porphyrin) Methylases K03394 - 2.1.1.130,2.1.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000001214 255.0
TLS3_k127_478050_28 helix_turn_helix ASNC type K03718 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001402 244.0
TLS3_k127_478050_29 Cobalt chelatase (CbiK) K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000000000000000000000000000000000001894 233.0
TLS3_k127_478050_3 Fibronectin-binding protein A N-terminus (FbpA) - - - 9.66e-215 685.0
TLS3_k127_478050_30 Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7 K02191 - 2.1.1.196 0.000000000000000000000000000000000000000000000000000000000000000002114 232.0
TLS3_k127_478050_31 RNA methylase - - - 0.0000000000000000000000000000000000000000000000000000000000000004002 229.0
TLS3_k127_478050_32 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.0000000000000000000000000000000000000000000000000000003107 197.0
TLS3_k127_478050_33 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000000000000000000000000000000000000004803 196.0
TLS3_k127_478050_34 - - - - 0.0000000000000000000000000000000000000000000000001163 181.0
TLS3_k127_478050_35 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.000000000000000000000000000000000000000000000003273 177.0
TLS3_k127_478050_36 - - - - 0.00000000000000000000000000000000000000000000005429 174.0
TLS3_k127_478050_37 Rio2, N-terminal K07179 - 2.7.11.1 0.00000000000000000000000000000000000000000003405 171.0
TLS3_k127_478050_38 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000000004697 169.0
TLS3_k127_478050_39 RecA RadA K04482,K04483 - - 0.0000000000000000000000000000000000000000002747 166.0
TLS3_k127_478050_4 S-adenosylmethionine synthetase K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 608.0
TLS3_k127_478050_40 Domain of unknown function (DUF427) - - - 0.0000000000000000000000000000000000000111 146.0
TLS3_k127_478050_41 PUA domain K07575 - - 0.000000000000000000000000000000000000633 144.0
TLS3_k127_478050_42 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.0000000000000000000000000000000004646 134.0
TLS3_k127_478050_43 PFAM Polyketide cyclase dehydrase - - - 0.00000000000000000000000000000001026 132.0
TLS3_k127_478050_44 snRNP Sm proteins K04796 - - 0.00000000000000000000000000000005323 128.0
TLS3_k127_478050_45 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000003436 123.0
TLS3_k127_478050_46 - - - - 0.000000000000000000000000000003703 124.0
TLS3_k127_478050_47 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.00000000000000000000000000001643 120.0
TLS3_k127_478050_48 Purple acid Phosphatase, N-terminal domain - - - 0.00000000000000000000039 104.0
TLS3_k127_478050_49 RNA polymerase Rpb3/Rpb11 dimerisation domain K03056 - 2.7.7.6 0.000000000000000000008899 95.0
TLS3_k127_478050_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 613.0
TLS3_k127_478050_51 ATP synthase subunit C K02124 - - 0.00000000000000002631 85.0
TLS3_k127_478050_52 - - - - 0.00000000000000002793 85.0
TLS3_k127_478050_53 - - - - 0.00000000000005343 72.0
TLS3_k127_478050_55 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.00000000001485 65.0
TLS3_k127_478050_57 PFAM Rieske 2Fe-2S domain - - - 0.00000000933 64.0
TLS3_k127_478050_59 zinc finger - - - 0.0002033 46.0
TLS3_k127_478050_6 PFAM tRNA synthetase, class II (D, K and N) K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006238 604.0
TLS3_k127_478050_60 HicA toxin of bacterial toxin-antitoxin, - - - 0.0002036 47.0
TLS3_k127_478050_7 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 581.0
TLS3_k127_478050_8 TIGRFAM 2-methylcitrate synthase citrate synthase II K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 573.0
TLS3_k127_478050_9 Tyrosine--tRNA ligase K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009173 495.0
TLS3_k127_4804805_0 MGS-like domain K01955 - 6.3.5.5 0.0 1469.0
TLS3_k127_4804805_1 carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 536.0
TLS3_k127_4804805_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 336.0
TLS3_k127_4804805_3 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000001743 250.0
TLS3_k127_4804805_4 Calcineurin-like phosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000001501 218.0
TLS3_k127_4804805_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000001463 133.0
TLS3_k127_4804805_6 Esterase-like activity of phytase K03929 - - 0.00000007907 61.0
TLS3_k127_4804805_7 MGS-like domain K01955 - 6.3.5.5 0.0008002 42.0
TLS3_k127_4821724_0 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K05710 - - 0.0000000000000000000000000000000000002358 143.0
TLS3_k127_483282_0 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000007371 163.0
TLS3_k127_483282_1 phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000000000000000000002676 143.0
TLS3_k127_4865597_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 455.0
TLS3_k127_4865597_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 360.0
TLS3_k127_4865597_2 COG1145 Ferredoxin - - - 0.000000000000000000000000000000006662 130.0
TLS3_k127_4865597_3 ASNC family K03718 - - 0.0000000000000005548 85.0
TLS3_k127_4865597_4 Sulfite exporter TauE/SafE K07090 - - 0.00000004314 55.0
TLS3_k127_4884580_0 Galactose oxidase, central domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 318.0
TLS3_k127_4884580_1 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002622 260.0
TLS3_k127_4884580_2 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000009097 116.0
TLS3_k127_4884580_3 - - - - 0.000000000000000000002569 101.0
TLS3_k127_4884580_4 Thiopurine S-methyltransferase (TPMT) - - - 0.00000000000000000007866 91.0
TLS3_k127_4884580_5 B12 binding domain K22491 - - 0.000000000001758 78.0
TLS3_k127_494962_0 COG3546 Mn-containing catalase K07217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 421.0
TLS3_k127_494962_1 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 426.0
TLS3_k127_494962_10 - - - - 0.0000000000000000000000000002408 115.0
TLS3_k127_494962_11 - - - - 0.000000000000000000003029 96.0
TLS3_k127_494962_12 Probable cobalt transporter subunit (CbtB) - - - 0.00000000000000000002421 93.0
TLS3_k127_494962_13 Protein of unknown function (DUF2795) - - - 0.000000000000000000095 93.0
TLS3_k127_494962_14 Protein of unknown function (DUF2795) - - - 0.0000000000004018 73.0
TLS3_k127_494962_16 PFAM (2R)-phospho-3-sulfolactate synthase ComA K08097 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 4.4.1.19 0.000000000146 62.0
TLS3_k127_494962_19 Protein of unknown function (DUF2795) - - - 0.0001454 46.0
TLS3_k127_494962_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007023 329.0
TLS3_k127_494962_3 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 314.0
TLS3_k127_494962_4 Probable cobalt transporter subunit (CbtA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001132 261.0
TLS3_k127_494962_5 PFAM beta-lactamase domain protein K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000002195 241.0
TLS3_k127_494962_6 Domain of unknown function (DUF4443) - - - 0.000000000000000000000000000000000000000000000001015 181.0
TLS3_k127_494962_8 PFAM phosphoesterase, PA-phosphatase related K19302 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.27 0.00000000000000000000000000000000006061 142.0
TLS3_k127_4977060_0 Methionine synthase K00548 - 2.1.1.13 0.0 1139.0
TLS3_k127_4977060_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009376 593.0
TLS3_k127_4977060_2 homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006414 508.0
TLS3_k127_4977060_3 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 445.0
TLS3_k127_4977060_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 289.0
TLS3_k127_4977060_5 Histidine-specific methyltransferase, SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001284 261.0
TLS3_k127_4977060_6 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000007571 237.0
TLS3_k127_508888_0 - - - - 0.0000000000000000006988 93.0
TLS3_k127_508888_1 - - - - 0.00005286 53.0
TLS3_k127_5178402_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 368.0
TLS3_k127_5251771_1 Belongs to the urease beta subunit family K01429,K14048 - 3.5.1.5 0.0000000000000000000000000000000000000000000000000000000001162 205.0
TLS3_k127_5251771_2 Urease, alpha subunit K01428 - 3.5.1.5 0.00000000000000000000000000000000000000000000000000007508 187.0
TLS3_k127_5251771_3 (urease) gamma subunit K01430,K14048 - 3.5.1.5 0.00000000000000000000000000000000000000000000001977 171.0
TLS3_k127_5251771_5 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.000000000000000005415 87.0
TLS3_k127_5258534_0 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 290.0
TLS3_k127_5258534_1 helicase activity K06915 - - 0.000000000000000000000000000000000000000000000000000000001118 222.0
TLS3_k127_5258534_2 Purple acid Phosphatase, N-terminal domain - - - 0.0000000000000000000000000000003086 136.0
TLS3_k127_5258534_4 Phosphatase - - - 0.000000002646 64.0
TLS3_k127_5258534_6 Phosphatase - - - 0.0004482 48.0
TLS3_k127_5269449_0 Sodium hydrogen exchanger K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 441.0
TLS3_k127_5269449_1 Cupin domain - - - 0.0000000000000000245 85.0
TLS3_k127_5269449_2 - - - - 0.00000000002955 69.0
TLS3_k127_5321704_0 PFAM TCP-1 cpn60 chaperonin family K22447 - - 1.915e-278 864.0
TLS3_k127_5321704_1 UbiD family decarboxylase K03182 - 4.1.1.98 9.092e-225 704.0
TLS3_k127_5321704_10 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 362.0
TLS3_k127_5321704_11 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 362.0
TLS3_k127_5321704_12 Catalyzes the conversion of dihydroorotate to orotate K00226,K00254,K17723,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.1,1.3.1.14,1.3.5.2,1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 347.0
TLS3_k127_5321704_13 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 329.0
TLS3_k127_5321704_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 322.0
TLS3_k127_5321704_15 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 294.0
TLS3_k127_5321704_16 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 290.0
TLS3_k127_5321704_17 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 284.0
TLS3_k127_5321704_18 glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006378 271.0
TLS3_k127_5321704_19 TatD related DNase K07051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004495 263.0
TLS3_k127_5321704_2 oligoendopeptidase F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 576.0
TLS3_k127_5321704_20 UPF0126 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000248 229.0
TLS3_k127_5321704_21 cytochrome-c peroxidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000003767 228.0
TLS3_k127_5321704_22 conserved protein implicated in secretion - - - 0.000000000000000000000000000000000000000000000000000000000000004251 223.0
TLS3_k127_5321704_23 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000183 201.0
TLS3_k127_5321704_24 thioesterase - - - 0.000000000000000000000000000000000000000000000000004172 184.0
TLS3_k127_5321704_25 - - - - 0.0000000000000000000000000000000000000000000000001917 181.0
TLS3_k127_5321704_26 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.00000000000000000000000000000000000000000000001171 175.0
TLS3_k127_5321704_27 - - - - 0.000000000000000000000000000000000000000000002871 167.0
TLS3_k127_5321704_28 Protein phosphatase 2C K20074 - 3.1.3.16 0.000000000000000000000000000000000000000001365 165.0
TLS3_k127_5321704_29 - - - - 0.00000000000000000000000000000000000000005799 160.0
TLS3_k127_5321704_3 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 541.0
TLS3_k127_5321704_30 PFAM phosphoesterase, PA-phosphatase related K19302 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.27 0.00000000000000000000000000000000000001886 152.0
TLS3_k127_5321704_31 NUDIX domain - - - 0.00000000000000000000000000000000000008907 148.0
TLS3_k127_5321704_32 - - - - 0.0000000000000000000000000000000000001097 144.0
TLS3_k127_5321704_33 - - - - 0.00000000000000000000000000000000003547 137.0
TLS3_k127_5321704_35 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000005342 116.0
TLS3_k127_5321704_36 Tetratricopeptide TPR-1 - - - 0.00000000000000000000000006306 119.0
TLS3_k127_5321704_4 inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 541.0
TLS3_k127_5321704_5 inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 471.0
TLS3_k127_5321704_6 NOSIC (NUC001) domain K14564 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 417.0
TLS3_k127_5321704_7 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 398.0
TLS3_k127_5321704_8 Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family K00555 - 2.1.1.215,2.1.1.216 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 382.0
TLS3_k127_5321704_9 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 369.0
TLS3_k127_5330297_0 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002187 269.0
TLS3_k127_5330297_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01546,K01548 - 3.6.3.12 0.00000000000000000000000000000000000000000000000004667 183.0
TLS3_k127_5330297_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000002493 182.0
TLS3_k127_5330297_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0000000000000002373 79.0
TLS3_k127_5331623_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000004927 49.0
TLS3_k127_5347384_0 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001228 256.0
TLS3_k127_5347384_1 Transcriptional regulatory protein, C terminal K18344 - - 0.000000000000104 76.0
TLS3_k127_5347384_3 Response regulator receiver domain protein - - - 0.0006633 47.0
TLS3_k127_5352258_0 Zinc-binding dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 398.0
TLS3_k127_5352258_1 GYD domain - - - 0.000000000005501 69.0
TLS3_k127_5355778_0 PFAM Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 494.0
TLS3_k127_5355778_1 divalent heavy-metal cations transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 452.0
TLS3_k127_5355778_2 iron dependent repressor - - - 0.0000000000000000000000000000000000000000000000000000000005645 205.0
TLS3_k127_5355778_3 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000008116 92.0
TLS3_k127_5355823_0 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005112 375.0
TLS3_k127_5355823_1 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000003934 240.0
TLS3_k127_5355823_10 - - - - 0.000000008018 62.0
TLS3_k127_5355823_12 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.00003134 48.0
TLS3_k127_5355823_2 Glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000002727 228.0
TLS3_k127_5355823_3 PFAM Ferritin, Dps family protein K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000000000000000001283 206.0
TLS3_k127_5355823_4 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000003051 153.0
TLS3_k127_5355823_5 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000009136 140.0
TLS3_k127_5355823_7 Purple acid Phosphatase, N-terminal domain - - - 0.0000000000000000000008735 109.0
TLS3_k127_5355823_9 Purple acid Phosphatase, N-terminal domain - - - 0.0000000009197 70.0
TLS3_k127_5385978_0 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 388.0
TLS3_k127_5385978_1 - - - - 0.00000000000000002775 88.0
TLS3_k127_5395942_0 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 1.087e-226 725.0
TLS3_k127_5395942_1 Acyl CoA acetate 3-ketoacid CoA transferase K01026 - 2.8.3.1 8.236e-194 618.0
TLS3_k127_5395942_10 Class II aldolase adducin family protein K01628 - 4.1.2.17 0.00000000000000000000000000000000000000001679 163.0
TLS3_k127_5395942_11 - - - - 0.0000000000000000000000000000003059 127.0
TLS3_k127_5395942_12 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000001074 133.0
TLS3_k127_5395942_13 PFAM GvpD gas vesicle - - - 0.0000000000000000000000000001488 131.0
TLS3_k127_5395942_14 Universal stress protein - - - 0.0000000000000000000000000689 112.0
TLS3_k127_5395942_15 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000000001117 92.0
TLS3_k127_5395942_16 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.000000000000000001058 92.0
TLS3_k127_5395942_17 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000002952 81.0
TLS3_k127_5395942_18 PFAM CBS domain - - - 0.0000000000371 69.0
TLS3_k127_5395942_19 CBS domain - - - 0.000000008393 67.0
TLS3_k127_5395942_2 Belongs to the carbamoyltransferase HypF family K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 608.0
TLS3_k127_5395942_3 PFAM hydrogenase formation HypD protein K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 464.0
TLS3_k127_5395942_4 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 400.0
TLS3_k127_5395942_5 ZIP Zinc transporter K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 336.0
TLS3_k127_5395942_6 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 296.0
TLS3_k127_5395942_7 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002213 244.0
TLS3_k127_5395942_8 PFAM Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000701 199.0
TLS3_k127_5395942_9 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000008055 173.0
TLS3_k127_5418881_0 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000005831 139.0
TLS3_k127_5428365_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000194 289.0
TLS3_k127_5428365_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008502 275.0
TLS3_k127_5428365_2 Periplasmic solute binding protein K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003442 266.0
TLS3_k127_5428365_3 COG3547 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000005661 205.0
TLS3_k127_5428365_4 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000006687 179.0
TLS3_k127_5428365_5 - - - - 0.000000000000000004235 89.0
TLS3_k127_5428365_6 COG3316 Transposase and inactivated derivatives K07498 - - 0.0000000000000004117 87.0
TLS3_k127_5428365_7 ChaB K06197 - - 0.0000000000000006732 80.0
TLS3_k127_5428365_8 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K01563 - 3.8.1.5 0.0000000003779 60.0
TLS3_k127_5428398_0 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002368 233.0
TLS3_k127_5432585_0 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003294 235.0
TLS3_k127_5432585_1 Hydrolase, alpha beta domain protein K00433 - 1.11.1.10 0.000000000000000000000000000000000000000000000000007903 189.0
TLS3_k127_5444461_0 CBS domain K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 551.0
TLS3_k127_5444461_1 Arsenical pump membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009524 490.0
TLS3_k127_5445302_0 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000001072 102.0
TLS3_k127_5445302_1 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.0000000000000002133 87.0
TLS3_k127_5447019_0 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 360.0
TLS3_k127_5447019_1 thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 328.0
TLS3_k127_5447019_2 thymidylate kinase K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008917 327.0
TLS3_k127_5447019_3 NAD(P)H-dependent FMN reductase K00299 - 1.5.1.38 0.0000000000000000000000000000000000000000000000000000000003671 208.0
TLS3_k127_5447019_4 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.00000111 51.0
TLS3_k127_5453895_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1366.0
TLS3_k127_5453895_1 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 5.693e-315 989.0
TLS3_k127_5453895_10 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000817 315.0
TLS3_k127_5453895_11 Belongs to the MCM family K10726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 297.0
TLS3_k127_5453895_12 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004401 261.0
TLS3_k127_5453895_13 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007532 243.0
TLS3_k127_5453895_14 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.00000000000000000000000000000000000000001447 156.0
TLS3_k127_5453895_15 Domain of unknown function (DUF309) K09763 - - 0.0000000000000000000000000000000000000002776 156.0
TLS3_k127_5453895_16 Domain of unknown function (DUF427) - - - 0.0000000000000000000000000000000000001395 143.0
TLS3_k127_5453895_17 - - - - 0.0000000000000000000000000000000001093 135.0
TLS3_k127_5453895_18 Nucleotide binding protein, PINc K07158 - - 0.0000000000000000000000000005512 117.0
TLS3_k127_5453895_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.951e-300 933.0
TLS3_k127_5453895_20 transcription factor (CBF NF-Y) - - - 0.0000000000000000002306 89.0
TLS3_k127_5453895_21 - - - - 0.00000000000000002885 81.0
TLS3_k127_5453895_22 CHRD domain - - - 0.00000000000000004155 89.0
TLS3_k127_5453895_24 - - - - 0.00000000000004579 76.0
TLS3_k127_5453895_25 - - - - 0.0000000000001772 72.0
TLS3_k127_5453895_3 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 4.031e-256 804.0
TLS3_k127_5453895_4 Initiation factor K03242 - - 7.342e-201 632.0
TLS3_k127_5453895_5 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 9.042e-200 626.0
TLS3_k127_5453895_6 TIGRFAM excinuclease ABC, C subunit K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 548.0
TLS3_k127_5453895_7 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 512.0
TLS3_k127_5453895_8 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 460.0
TLS3_k127_5453895_9 Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 421.0
TLS3_k127_5462198_0 DNA polymerase IV (family X) K02347 - - 1.352e-228 723.0
TLS3_k127_5462198_1 Collagen triple helix repeat (20 copies) - - - 0.0000161 53.0
TLS3_k127_5489936_0 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 6.578e-243 754.0
TLS3_k127_5489936_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 575.0
TLS3_k127_5489936_10 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003985 278.0
TLS3_k127_5489936_11 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005967 265.0
TLS3_k127_5489936_12 Protein of unknown function (DUF763) K09003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001628 252.0
TLS3_k127_5489936_13 D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000005822 247.0
TLS3_k127_5489936_14 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000001593 203.0
TLS3_k127_5489936_15 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000000001143 192.0
TLS3_k127_5489936_16 Phosphoesterase family K01114 - 3.1.4.3 0.0000000000000000000000000000000000000000000000000003645 207.0
TLS3_k127_5489936_17 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000405 185.0
TLS3_k127_5489936_18 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000000000000000000001139 150.0
TLS3_k127_5489936_19 - - - - 0.0000000000000000000000000006391 116.0
TLS3_k127_5489936_2 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 539.0
TLS3_k127_5489936_20 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000001022 110.0
TLS3_k127_5489936_21 - - - - 0.00000000000000000000002736 110.0
TLS3_k127_5489936_22 Ribosomal protein S30 K02983 - - 0.00000000000000000006047 90.0
TLS3_k127_5489936_23 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000000000008763 90.0
TLS3_k127_5489936_24 Cupin - - - 0.0000000000000000002286 94.0
TLS3_k127_5489936_26 - - - - 0.0000000000000000801 83.0
TLS3_k127_5489936_27 glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000001473 85.0
TLS3_k127_5489936_28 endonuclease K00986 - 2.7.7.49 0.000000000000001261 79.0
TLS3_k127_5489936_29 zinc finger - - - 0.000000000000003698 77.0
TLS3_k127_5489936_3 COG1960 Acyl-CoA dehydrogenases K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 526.0
TLS3_k127_5489936_31 - - - - 0.000000000001341 68.0
TLS3_k127_5489936_33 IMP dehydrogenase activity K04767 - - 0.000000134 60.0
TLS3_k127_5489936_36 - - - - 0.0001032 45.0
TLS3_k127_5489936_37 - - - - 0.0001038 51.0
TLS3_k127_5489936_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 503.0
TLS3_k127_5489936_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K00836 - 2.6.1.19,2.6.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 451.0
TLS3_k127_5489936_6 D-isomer specific 2-hydroxyacid dehydrogenase K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 331.0
TLS3_k127_5489936_7 DNA-directed RNA polymerase K03049 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 315.0
TLS3_k127_5489936_8 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 287.0
TLS3_k127_5489936_9 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001424 283.0
TLS3_k127_5504388_0 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 289.0
TLS3_k127_5504388_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.0000000000000000000000000000002388 129.0
TLS3_k127_5504388_2 Universal stress protein - - - 0.000000000000000000000001541 108.0
TLS3_k127_5504388_3 amino acid K03294 - - 0.0000000001027 63.0
TLS3_k127_5504388_4 transcriptional - - - 0.0002844 47.0
TLS3_k127_5515724_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 1.014e-314 969.0
TLS3_k127_5515724_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.018e-267 842.0
TLS3_k127_5515724_10 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 533.0
TLS3_k127_5515724_11 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 535.0
TLS3_k127_5515724_12 PFAM tRNA synthetases class I (C) catalytic domain K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 530.0
TLS3_k127_5515724_13 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 491.0
TLS3_k127_5515724_14 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 473.0
TLS3_k127_5515724_15 ribosomal protein L3 K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 455.0
TLS3_k127_5515724_16 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 449.0
TLS3_k127_5515724_17 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 420.0
TLS3_k127_5515724_18 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 402.0
TLS3_k127_5515724_19 PHP-associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 402.0
TLS3_k127_5515724_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 7.657e-263 817.0
TLS3_k127_5515724_20 PFAM SPFH domain Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 400.0
TLS3_k127_5515724_21 LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 386.0
TLS3_k127_5515724_22 Proteasome endopeptidase complex K03432 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 371.0
TLS3_k127_5515724_23 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 369.0
TLS3_k127_5515724_24 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 372.0
TLS3_k127_5515724_25 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000954 349.0
TLS3_k127_5515724_26 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 328.0
TLS3_k127_5515724_27 Ribosomal protein L4 K02930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 313.0
TLS3_k127_5515724_28 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 306.0
TLS3_k127_5515724_29 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 309.0
TLS3_k127_5515724_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 9.552e-254 794.0
TLS3_k127_5515724_30 resolvase K14060 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 302.0
TLS3_k127_5515724_31 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 302.0
TLS3_k127_5515724_32 Phosphoglycolate phosphatase K22223 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 296.0
TLS3_k127_5515724_33 Binds the lower part of the 30S subunit head K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 297.0
TLS3_k127_5515724_34 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 299.0
TLS3_k127_5515724_35 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002028 287.0
TLS3_k127_5515724_36 UbiA prenyltransferase K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002413 286.0
TLS3_k127_5515724_37 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000706 278.0
TLS3_k127_5515724_38 conserved protein implicated in secretion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006796 269.0
TLS3_k127_5515724_39 Aminotransferase class I and II K00639,K00652,K01906 - 2.3.1.29,2.3.1.47,6.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000001858 273.0
TLS3_k127_5515724_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 6.821e-252 786.0
TLS3_k127_5515724_40 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001992 252.0
TLS3_k127_5515724_41 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009328 247.0
TLS3_k127_5515724_42 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001867 245.0
TLS3_k127_5515724_43 acetolactate synthase, small K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000003792 238.0
TLS3_k127_5515724_44 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000004493 232.0
TLS3_k127_5515724_45 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000009231 231.0
TLS3_k127_5515724_46 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000000000321 227.0
TLS3_k127_5515724_47 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000000000000000000000000000004808 225.0
TLS3_k127_5515724_48 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000006006 222.0
TLS3_k127_5515724_49 Cytidylyltransferase-like K00952 - 2.7.7.1 0.000000000000000000000000000000000000000000000000000000000002402 213.0
TLS3_k127_5515724_5 Protein of unknown function, DUF255 K06888 - - 7.966e-252 795.0
TLS3_k127_5515724_50 Putative RNA methyltransferase K09142 - - 0.000000000000000000000000000000000000000000000000000000000002835 219.0
TLS3_k127_5515724_51 Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000001949 207.0
TLS3_k127_5515724_52 - - - - 0.000000000000000000000000000000000000000000000000619 177.0
TLS3_k127_5515724_53 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.000000000000000000000000000000000000000000000005112 180.0
TLS3_k127_5515724_54 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000000000000000003658 165.0
TLS3_k127_5515724_55 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000000000000000000000005641 167.0
TLS3_k127_5515724_56 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000002068 166.0
TLS3_k127_5515724_57 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K00363,K15762 - 1.7.1.15 0.00000000000000000000000000000000000000000002287 162.0
TLS3_k127_5515724_58 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000004468 154.0
TLS3_k127_5515724_59 Domain of unknown function (DUF371) K09738 - - 0.0000000000000000000000000000000000001475 145.0
TLS3_k127_5515724_6 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 5.4e-231 722.0
TLS3_k127_5515724_60 - - - - 0.00000000000000000000000000000008519 126.0
TLS3_k127_5515724_61 - - - - 0.0000000000000000000000000001187 119.0
TLS3_k127_5515724_62 - - - - 0.000000000000000000000000003124 112.0
TLS3_k127_5515724_63 ribosomal protein S14 K02954 - - 0.00000000000000000000000003612 108.0
TLS3_k127_5515724_64 - - - - 0.00000000000000000000000008977 111.0
TLS3_k127_5515724_65 Located at the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000002437 108.0
TLS3_k127_5515724_66 - - - - 0.0000000000000000000000192 109.0
TLS3_k127_5515724_67 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.000000000000000000001061 98.0
TLS3_k127_5515724_68 RNA-binding protein contains TRAM domain - - - 0.000000000000000000001114 96.0
TLS3_k127_5515724_69 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000001432 98.0
TLS3_k127_5515724_7 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 8.56e-227 709.0
TLS3_k127_5515724_70 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000000001407 92.0
TLS3_k127_5515724_71 ferredoxin - - - 0.00000000000000000002653 89.0
TLS3_k127_5515724_72 Type I secretion target repeat protein - - - 0.000000000000000001724 93.0
TLS3_k127_5515724_73 YHS domain - - - 0.0000000000000001407 79.0
TLS3_k127_5515724_74 IMP dehydrogenase activity - - - 0.0000000001027 63.0
TLS3_k127_5515724_75 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.0000000001333 68.0
TLS3_k127_5515724_76 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.000000006811 60.0
TLS3_k127_5515724_77 - - - - 0.000000006939 58.0
TLS3_k127_5515724_8 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 576.0
TLS3_k127_5515724_9 component I K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 546.0
TLS3_k127_5520819_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 7.702e-282 874.0
TLS3_k127_5520819_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 547.0
TLS3_k127_5520819_10 - - - - 0.00000000000000000000000000000000000000001339 154.0
TLS3_k127_5520819_11 - - - - 0.00000000000000000000000000000000000000105 149.0
TLS3_k127_5520819_13 Protein of unknown function (DUF4242) - - - 0.00000000000000000002173 92.0
TLS3_k127_5520819_14 Dodecin K09165 - - 0.000000001482 61.0
TLS3_k127_5520819_2 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006809 514.0
TLS3_k127_5520819_3 Alpha beta hydrolase K01066,K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 465.0
TLS3_k127_5520819_4 Archaeal ammonia monooxygenase subunit A (AmoA) K10944 - 1.14.18.3,1.14.99.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 417.0
TLS3_k127_5520819_5 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 300.0
TLS3_k127_5520819_6 Monooxygenase subunit B protein K10945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007717 248.0
TLS3_k127_5520819_7 ribosomal protein K02956 - - 0.00000000000000000000000000000000000000000000000000000000000001418 218.0
TLS3_k127_5520819_8 KR domain - - - 0.0000000000000000000000000000000000000000000000001138 185.0
TLS3_k127_5520819_9 HIT domain K02503 - - 0.00000000000000000000000000000000000000000000004896 175.0
TLS3_k127_5535295_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 329.0
TLS3_k127_5535295_1 - - - - 0.0000000000000000000000000000000000000000000000000007126 196.0
TLS3_k127_5535295_2 Sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000007741 152.0
TLS3_k127_5535295_3 - - - - 0.000000000000000000000000001053 121.0
TLS3_k127_5535295_4 - - - - 0.0000000000000000003021 89.0
TLS3_k127_5571326_0 DJ-1/PfpI family - - - 0.000000003542 58.0
TLS3_k127_5571326_1 - - - - 0.00000006278 64.0
TLS3_k127_5624983_0 - - - - 0.000000000000000000000000000000000000000000000005459 179.0
TLS3_k127_5624983_1 DsrE/DsrF-like family - - - 0.000001117 52.0
TLS3_k127_5666107_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 371.0
TLS3_k127_5666107_1 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000008771 245.0
TLS3_k127_5666107_2 multicopper - - - 0.000000000000000007981 87.0
TLS3_k127_5666107_3 response regulator, receiver - - - 0.0000000000000002087 84.0
TLS3_k127_5666107_4 response regulator, receiver K02490 - - 0.0000000000003928 74.0
TLS3_k127_5666107_5 Transcriptional regulatory protein, C terminal - - - 0.000000005269 61.0
TLS3_k127_5685280_0 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.000000000000000000000000000000000000000003126 158.0
TLS3_k127_5685280_2 Transcriptional regulator - - - 0.000000000000111 74.0
TLS3_k127_5685280_3 - - - - 0.00000001262 56.0
TLS3_k127_5685280_4 - - - - 0.0000002327 52.0
TLS3_k127_5723142_0 TIGRFAM phosphate ABC transporter K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 451.0
TLS3_k127_5723142_1 Phosphate uptake regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 409.0
TLS3_k127_5723142_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 391.0
TLS3_k127_5723142_3 binding-protein-dependent transport systems inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000009913 235.0
TLS3_k127_57238_0 Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000002782 160.0
TLS3_k127_57238_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.00000000000000000000000000001716 123.0
TLS3_k127_57238_2 SnoaL-like domain - - - 0.000000000000000000000008611 105.0
TLS3_k127_57238_3 Purple acid Phosphatase, N-terminal domain - - - 0.000000000000000005136 96.0
TLS3_k127_57238_4 SPTR Transposase, IS4 family protein - - - 0.00000000000001192 74.0
TLS3_k127_57238_5 alginic acid biosynthetic process K09483 - 4.2.1.118 0.0000000000007649 78.0
TLS3_k127_57238_6 membrane - - - 0.00000000001523 70.0
TLS3_k127_5735118_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.509e-248 776.0
TLS3_k127_5735118_1 HMGL-like K01649 - 2.3.3.13 5.295e-214 670.0
TLS3_k127_5735118_10 Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis) K05828 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 398.0
TLS3_k127_5735118_11 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 413.0
TLS3_k127_5735118_12 Lysine biosynthesis K05827 - 6.3.2.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 378.0
TLS3_k127_5735118_13 diphthine synthase K20215 - 2.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 362.0
TLS3_k127_5735118_14 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000006518 269.0
TLS3_k127_5735118_15 Cobalamin B12-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001082 232.0
TLS3_k127_5735118_16 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000000000000000000000000000000000000000000000009597 203.0
TLS3_k127_5735118_17 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000005938 191.0
TLS3_k127_5735118_18 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.00000000000000000000000000000000000000000000000009405 183.0
TLS3_k127_5735118_19 ribosomal protein K02976 - - 0.0000000000000000000000000000000000000000000006325 168.0
TLS3_k127_5735118_2 Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily K05829 - - 1.658e-198 621.0
TLS3_k127_5735118_20 helix_turn_helix ASNC type - - - 0.000000000000000000000000000000000000001245 151.0
TLS3_k127_5735118_21 PIN domain of ribonuclease K07060 - - 0.000000000000000000000000000007295 124.0
TLS3_k127_5735118_22 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000006863 108.0
TLS3_k127_5735118_23 lysine biosynthesis protein LysW K05826 - - 0.0000000000000000000001017 97.0
TLS3_k127_5735118_24 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000000000000000005893 110.0
TLS3_k127_5735118_25 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000004818 104.0
TLS3_k127_5735118_26 PFAM GvpD gas vesicle - - - 0.0000000000000000000995 103.0
TLS3_k127_5735118_27 lysine biosynthesis protein LysW K05826 - - 0.0000000000000000001066 89.0
TLS3_k127_5735118_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 601.0
TLS3_k127_5735118_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K05830 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 595.0
TLS3_k127_5735118_5 Catalyzes the release of L-lysine from LysW -gamma-L- lysine and the release of L-ornithine from LysW -L-ornithine K05831 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 555.0
TLS3_k127_5735118_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 462.0
TLS3_k127_5735118_7 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 456.0
TLS3_k127_5735118_8 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 447.0
TLS3_k127_5735118_9 Lysine biosynthesis K05827 - 6.3.2.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 412.0
TLS3_k127_5735542_0 DDE superfamily endonuclease - - - 0.000000000001642 75.0
TLS3_k127_5735542_1 Homeodomain-like domain - - - 0.0000001691 59.0
TLS3_k127_5736697_0 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 369.0
TLS3_k127_5736697_1 - - - - 0.00001327 53.0
TLS3_k127_5757370_0 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 312.0
TLS3_k127_5757370_1 elongation factor Tu - - - 0.00000000000000000000000000000000000000000000000000000000000000002376 229.0
TLS3_k127_5757370_2 - - - - 0.000000000000000000001682 96.0
TLS3_k127_5757370_3 Putative esterase - - - 0.000001078 52.0
TLS3_k127_5760375_0 UV-endonuclease UvdE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 325.0
TLS3_k127_5760375_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000001685 235.0
TLS3_k127_5760375_3 pyrroloquinoline quinone binding - - - 0.00000000001051 67.0
TLS3_k127_5760375_4 phosphorelay signal transduction system - - - 0.0000009244 56.0
TLS3_k127_5981138_0 - - - - 0.0000000000000000000000000000000000000000000003782 173.0
TLS3_k127_5981138_1 - - - - 0.0000000000000000000000002713 116.0
TLS3_k127_5981138_2 - - - - 0.00000000003746 66.0
TLS3_k127_5981138_3 PFAM DsrE family protein K06039,K07235 - - 0.0000000002333 67.0
TLS3_k127_6087843_0 COG3316 Transposase and inactivated derivatives K07498 - - 0.00000000000001793 82.0
TLS3_k127_6087843_1 Winged helix-turn-helix - - - 0.0000000000003951 71.0
TLS3_k127_610989_0 - - - - 0.000000000000000000000003106 103.0
TLS3_k127_6166474_0 Epimerase dehydratase K01784,K12454 - 5.1.3.10,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 363.0
TLS3_k127_6166474_1 RTX toxins and related Ca2 binding proteins - - - 0.0000000000000000000007985 107.0
TLS3_k127_6224661_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.243e-232 733.0
TLS3_k127_6224661_1 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 9.139e-224 712.0
TLS3_k127_6224661_10 Nicotinamide-nucleotide adenylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000009657 227.0
TLS3_k127_6224661_11 Circadian clock protein KaiC K08482 - - 0.00000000000000000000000000000000000000000000000000000004169 216.0
TLS3_k127_6224661_12 Iron-sulfur cluster assembly protein - - - 0.000000000000000000000000000000000000000000003536 166.0
TLS3_k127_6224661_13 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000007718 164.0
TLS3_k127_6224661_14 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000000000000000000000000000000000000005337 151.0
TLS3_k127_6224661_15 ATP synthase subunit C K02124 - - 0.000000000000000000000000004073 113.0
TLS3_k127_6224661_16 Trm112p-like protein - - - 0.0000000000000000000000005618 108.0
TLS3_k127_6224661_17 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000006654 81.0
TLS3_k127_6224661_18 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000000000005213 76.0
TLS3_k127_6224661_19 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0004487 49.0
TLS3_k127_6224661_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 4.397e-219 687.0
TLS3_k127_6224661_3 argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000979 466.0
TLS3_k127_6224661_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 421.0
TLS3_k127_6224661_5 Oxidoreductase family, NAD-binding Rossmann fold K18855 - 1.1.1.374 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 408.0
TLS3_k127_6224661_6 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 401.0
TLS3_k127_6224661_7 Protein of unknown function (DUF354) K09726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009473 325.0
TLS3_k127_6224661_8 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007272 250.0
TLS3_k127_6224661_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000000000000000000000000000000000000000000000000000000000000000001312 246.0
TLS3_k127_6226080_0 Ferritin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 319.0
TLS3_k127_6226080_1 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001241 263.0
TLS3_k127_6226080_11 Protein of unknown function (DUF2795) - - - 0.000000000011 67.0
TLS3_k127_6226080_12 response regulator receiver - - - 0.0000000002389 66.0
TLS3_k127_6226080_3 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004636 254.0
TLS3_k127_6226080_4 Protein of unknown function (DUF2795) - - - 0.000000000000000000000000000000000000000000000000000000000000000756 222.0
TLS3_k127_6226080_5 Glycosyl transferases group 1 - - - 0.00000000000000000000000005737 120.0
TLS3_k127_6226080_6 Protein of unknown function (DUF2795) - - - 0.0000000000000000000006034 100.0
TLS3_k127_6226080_7 Erythromycin esterase K06880 - - 0.00000000000000000002849 91.0
TLS3_k127_6226080_8 Protein of unknown function, DUF488 - - - 0.0000000000000001163 84.0
TLS3_k127_6226080_9 Protein of unknown function (DUF2795) - - - 0.000000000000007432 77.0
TLS3_k127_6237829_0 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00001965 48.0
TLS3_k127_6239976_0 aldo-keto reductase (NADP) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 357.0
TLS3_k127_6239976_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 352.0
TLS3_k127_6239976_2 response regulator, receiver - - - 0.0000000000000000000000005479 109.0
TLS3_k127_6239976_4 Transposase K07498 - - 0.00000000006684 71.0
TLS3_k127_6239976_5 - - - - 0.0000000002 67.0
TLS3_k127_6309876_0 PhoU domain K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001978 274.0
TLS3_k127_635306_1 - - - - 0.00005188 48.0
TLS3_k127_635306_2 PFAM NAD-dependent epimerase dehydratase K01784,K08678 - 4.1.1.35,5.1.3.2 0.0002207 45.0
TLS3_k127_635908_0 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.00000000000000000000000000001314 123.0
TLS3_k127_635908_1 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000534 110.0
TLS3_k127_635908_2 Glyoxalase-like domain K01759 - 4.4.1.5 0.0000000000000007758 83.0
TLS3_k127_6373475_0 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.00000000000000000000000000000003466 136.0
TLS3_k127_6392331_0 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000007883 179.0
TLS3_k127_6480516_0 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000002472 149.0
TLS3_k127_6497548_0 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000000000000000000000002217 240.0
TLS3_k127_6497548_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000001388 208.0
TLS3_k127_6497548_2 - - - - 0.000000000000000007451 85.0
TLS3_k127_6497548_3 PFAM Ammonia monooxygenase methane monooxygenase, subunit C K10946 - - 0.00000000000000001446 81.0
TLS3_k127_6497548_4 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000001602 72.0
TLS3_k127_6497548_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000009131 57.0
TLS3_k127_6505577_0 Belongs to the complex I 20 kDa subunit family K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 326.0
TLS3_k127_6539447_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 359.0
TLS3_k127_6539447_1 Pyridoxamine 5'-phosphate - - - 0.000000000000000000000000000000000000000003603 160.0
TLS3_k127_6539447_2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.000000000000000000000001217 109.0
TLS3_k127_6539447_3 Hydrolase, alpha beta domain protein K00433 - 1.11.1.10 0.0000000000000000000007749 97.0
TLS3_k127_6539447_4 Serine aminopeptidase, S33 - - - 0.0000000000000004233 82.0
TLS3_k127_6539447_5 Serine aminopeptidase, S33 - - - 0.000001858 51.0
TLS3_k127_6645266_0 Belongs to the MCM family K10726 - - 0.0 1057.0
TLS3_k127_6645266_1 PFAM TCP-1 cpn60 chaperonin family K22447 - - 2.022e-283 878.0
TLS3_k127_6645266_10 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 354.0
TLS3_k127_6645266_11 Chlorite dismutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 344.0
TLS3_k127_6645266_12 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 319.0
TLS3_k127_6645266_13 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 317.0
TLS3_k127_6645266_14 DNA-directed RNA polymerase, alpha subunit 40 kD subunit K03047 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 312.0
TLS3_k127_6645266_15 Queuosine biosynthesis protein QueC K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 291.0
TLS3_k127_6645266_16 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004077 276.0
TLS3_k127_6645266_17 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001185 248.0
TLS3_k127_6645266_18 Transcription elongation factor Spt5 K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004625 243.0
TLS3_k127_6645266_19 Pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000003015 241.0
TLS3_k127_6645266_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 3.347e-245 772.0
TLS3_k127_6645266_20 ERCC4 domain K10848 - - 0.00000000000000000000000000000000000000000000000000000000000000000002794 239.0
TLS3_k127_6645266_21 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000000003748 232.0
TLS3_k127_6645266_22 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000008595 216.0
TLS3_k127_6645266_23 - - - - 0.000000000000000000000000000000000000000000000000000000002691 204.0
TLS3_k127_6645266_24 Cytidylyltransferase-like K00952 - 2.7.7.1 0.0000000000000000000000000000000000000000000000000001562 191.0
TLS3_k127_6645266_25 - - - - 0.0000000000000000000000000000000000000000000000000004435 191.0
TLS3_k127_6645266_26 GINS complex protein K09723 - - 0.000000000000000000000000000000000000000000000000002297 188.0
TLS3_k127_6645266_27 Domain of unknown function (DUF1802) - - - 0.00000000000000000000000000000000000000000000008924 177.0
TLS3_k127_6645266_29 - - - - 0.000000000000000000000000000000000000000000002529 170.0
TLS3_k127_6645266_3 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008802 494.0
TLS3_k127_6645266_30 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.000000000000000000000000000000000000002971 149.0
TLS3_k127_6645266_31 ribosomal protein K02883 - - 0.000000000000000000000000000000000000009185 148.0
TLS3_k127_6645266_32 Belongs to the class-I aminoacyl-tRNA synthetase family - - - 0.00000000000000000000000000000000002699 136.0
TLS3_k127_6645266_33 zinc-ribbon domain - - - 0.000000000000000000000000000002254 124.0
TLS3_k127_6645266_34 Ribosomal L37ae protein family K02921 - - 0.000000000000000000000000000006713 120.0
TLS3_k127_6645266_35 COGs COG3316 Transposase and inactivated derivatives - - - 0.000000000000000000000000000009507 126.0
TLS3_k127_6645266_37 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000001419 109.0
TLS3_k127_6645266_39 - - - - 0.0000000294 56.0
TLS3_k127_6645266_4 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009891 488.0
TLS3_k127_6645266_40 COG3316 Transposase and inactivated derivatives - - - 0.00001795 48.0
TLS3_k127_6645266_41 DNA topoisomerase, type IA, central domain protein K03168,K03169 - 5.99.1.2 0.00003529 49.0
TLS3_k127_6645266_42 transposition, DNA-mediated - - - 0.0002532 48.0
TLS3_k127_6645266_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 461.0
TLS3_k127_6645266_6 FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 422.0
TLS3_k127_6645266_7 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 404.0
TLS3_k127_6645266_8 Replication factor C K04801 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 394.0
TLS3_k127_6645266_9 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 366.0
TLS3_k127_6668684_0 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008438 267.0
TLS3_k127_6668684_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000007075 166.0
TLS3_k127_6668684_2 amine dehydrogenase activity - - - 0.000000000000000001094 94.0
TLS3_k127_6668684_3 Purple acid Phosphatase, N-terminal domain - - - 0.00000000000000000269 98.0
TLS3_k127_6668941_0 UbiD family decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 580.0
TLS3_k127_6668941_1 Protein of unknown function (DUF790) K09744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 352.0
TLS3_k127_6668941_2 - - - - 0.0000000000000000000000000000000000000000000000008088 182.0
TLS3_k127_6668941_6 TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000004421 139.0
TLS3_k127_6668941_7 Mg2 transporter protein K03284 - - 0.0000000000003049 72.0
TLS3_k127_6668941_8 - - - - 0.000000000356 65.0
TLS3_k127_6668941_9 Concanavalin A-like lectin/glucanases superfamily - - - 0.0001966 51.0
TLS3_k127_6742020_0 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000002708 96.0
TLS3_k127_6813679_0 - - - - 0.00000000000000000000000000000000003031 142.0
TLS3_k127_6813679_1 Predicted membrane protein (DUF2254) - - - 0.00000000000003469 86.0
TLS3_k127_6813679_2 Transcriptional regulator - - - 0.00000000000004151 75.0
TLS3_k127_6813679_3 - - - - 0.000000000002524 70.0
TLS3_k127_6813679_4 - - - - 0.0001375 50.0
TLS3_k127_6813679_5 transcription factor jumonji K18850 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016491,GO:0016705,GO:0016706,GO:0018193,GO:0018195,GO:0019538,GO:0030961,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:1901564 1.14.11.47 0.000207 52.0
TLS3_k127_6823012_0 DnaJ-class molecular chaperone with C-terminal Zn finger domain - - - 0.00000000000000000000000000000000000000001968 158.0
TLS3_k127_6823012_1 - - - - 0.00000000000000000000000000000000000000004494 164.0
TLS3_k127_6838767_0 - - - - 0.00000000000000000000000000000000000000003303 163.0
TLS3_k127_6841271_0 COG1335 Amidases related to nicotinamidase K09020 - 3.5.1.110 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002123 278.0
TLS3_k127_6841271_1 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000002068 115.0
TLS3_k127_6852595_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1400.0
TLS3_k127_6852595_1 Radical SAM - - - 0.0 1057.0
TLS3_k127_6852595_10 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006338 492.0
TLS3_k127_6852595_11 aspartate carbamoyltransferase K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 481.0
TLS3_k127_6852595_12 Chorismate mutase type II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 482.0
TLS3_k127_6852595_13 DNA methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 473.0
TLS3_k127_6852595_14 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 471.0
TLS3_k127_6852595_15 TIGRFAM poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007244 473.0
TLS3_k127_6852595_16 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009976 462.0
TLS3_k127_6852595_17 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 432.0
TLS3_k127_6852595_18 Cysteine desulfurase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 436.0
TLS3_k127_6852595_19 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 425.0
TLS3_k127_6852595_2 Carbamoyl-phosphate synthase L chain K18603 - 6.4.1.2,6.4.1.3 8.968e-242 754.0
TLS3_k127_6852595_20 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 403.0
TLS3_k127_6852595_21 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009474 409.0
TLS3_k127_6852595_22 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 399.0
TLS3_k127_6852595_23 Belongs to the universal ribosomal protein uS5 family K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 342.0
TLS3_k127_6852595_24 phosphohydrolase (DHH superfamily) K07097 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009015 340.0
TLS3_k127_6852595_25 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 320.0
TLS3_k127_6852595_26 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 301.0
TLS3_k127_6852595_27 tRNA methyl transferase K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 299.0
TLS3_k127_6852595_28 GHMP kinases N terminal domain K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 291.0
TLS3_k127_6852595_29 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001032 267.0
TLS3_k127_6852595_3 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 5.883e-236 740.0
TLS3_k127_6852595_30 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001304 267.0
TLS3_k127_6852595_31 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000001637 248.0
TLS3_k127_6852595_32 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000000000000000000001681 222.0
TLS3_k127_6852595_33 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000003562 216.0
TLS3_k127_6852595_34 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000008403 215.0
TLS3_k127_6852595_35 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000946 216.0
TLS3_k127_6852595_36 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000001659 212.0
TLS3_k127_6852595_37 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000008857 200.0
TLS3_k127_6852595_38 ribosomal protein K02907 - - 0.000000000000000000000000000000000000000000000000000007973 192.0
TLS3_k127_6852595_39 Belongs to the archaeal adenylate kinase family K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000233 190.0
TLS3_k127_6852595_4 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 7.7e-226 707.0
TLS3_k127_6852595_40 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000007496 194.0
TLS3_k127_6852595_41 biotin carboxyl carrier K00627,K01571,K15037,K18605 - 2.3.1.12,4.1.1.3 0.0000000000000000000000000000000000000000000003593 172.0
TLS3_k127_6852595_42 Sua5 YciO YrdC YwlC family K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000001431 166.0
TLS3_k127_6852595_43 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.0000000000000000000000000000000000000001983 153.0
TLS3_k127_6852595_44 conserved protein implicated in secretion - - - 0.0000000000000000000000000000000000007354 147.0
TLS3_k127_6852595_45 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000008165 140.0
TLS3_k127_6852595_46 THUMP domain K06963 - - 0.00000000000000000000000000000000001058 143.0
TLS3_k127_6852595_47 - - - - 0.00000000000000000000000000000000007597 137.0
TLS3_k127_6852595_48 Belongs to the UPF0201 family K09736 - - 0.0000000000000000000000000000006502 126.0
TLS3_k127_6852595_49 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.000000000000000000000328 97.0
TLS3_k127_6852595_5 Thiolase, N-terminal domain K00626 - 2.3.1.9 1.666e-218 681.0
TLS3_k127_6852595_50 - - - - 0.00000000000000000002054 96.0
TLS3_k127_6852595_52 response regulator, receiver - - - 0.000000000000000067 85.0
TLS3_k127_6852595_53 Kinase binding protein CGI-121 - - - 0.000000000000007397 77.0
TLS3_k127_6852595_54 - - - - 0.00000000000001198 75.0
TLS3_k127_6852595_55 Kinase binding protein CGI-121 - - - 0.0000000000005101 76.0
TLS3_k127_6852595_56 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000002985 66.0
TLS3_k127_6852595_57 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.0000001056 61.0
TLS3_k127_6852595_59 Transcriptional regulator - - - 0.000002408 53.0
TLS3_k127_6852595_6 Histone acetyltransferase K07739 - 2.3.1.48 4.472e-204 648.0
TLS3_k127_6852595_7 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 617.0
TLS3_k127_6852595_8 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 551.0
TLS3_k127_6852595_9 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K18604 - 2.1.3.15,6.4.1.2,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 522.0
TLS3_k127_6883195_0 PFAM Iron dependent repressor, metal binding and dimerisation domain K03709 - - 0.0000000000000000000000000000000000000000000001078 169.0
TLS3_k127_6883195_1 - - - - 0.0001233 46.0
TLS3_k127_6884320_0 NAD(P)H-quinone oxidoreductase chain 4, chloroplastic K05575 - 1.6.5.3 7.005e-258 801.0
TLS3_k127_6884320_1 Cytochrome c biogenesis protein CcsA - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0008150,GO:0008152,GO:0009536,GO:0015886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:1901678 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 427.0
TLS3_k127_6884320_2 essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA B D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn K02691 - - 0.00000000000000000000000000000000000000000000000006653 177.0
TLS3_k127_6884320_3 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic K05576 GO:0003674,GO:0003824,GO:0003954,GO:0003959,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008137,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009987,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031976,GO:0031984,GO:0032991,GO:0034357,GO:0042180,GO:0042181,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050136,GO:0051186,GO:0051188,GO:0055035,GO:0055114,GO:0071704,GO:0098796,GO:1901576,GO:1901661,GO:1901663,GO:1902494 1.6.5.3 0.000000000000000000000000000000000000000003659 156.0
TLS3_k127_6884320_4 50S ribosomal protein L32 K02911 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.00000000001731 67.0
TLS3_k127_6885605_0 COG1335 Amidases related to nicotinamidase K09020 - 3.5.1.110 0.000000000000000000000000000000000000000000000000000000000000000000000000004293 258.0
TLS3_k127_6885605_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.00000000003579 66.0
TLS3_k127_6885605_2 Universal stress protein - - - 0.00000000103 69.0
TLS3_k127_6885605_3 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.000002231 52.0
TLS3_k127_6885605_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000104 57.0
TLS3_k127_6891524_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 4.637e-269 850.0
TLS3_k127_6891524_1 RNA-metabolising metallo-beta-lactamase K07041 - - 4.211e-201 645.0
TLS3_k127_6891524_10 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 345.0
TLS3_k127_6891524_11 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 313.0
TLS3_k127_6891524_12 Peptidyl-prolyl cis-trans K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 311.0
TLS3_k127_6891524_13 kinase, sugar kinase superfamily K06982 - 2.7.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 303.0
TLS3_k127_6891524_14 PFAM ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 284.0
TLS3_k127_6891524_15 ABC 3 transport family K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002657 287.0
TLS3_k127_6891524_16 Pfam:DUF137 K09722 - 6.3.2.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001149 281.0
TLS3_k127_6891524_17 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000008528 237.0
TLS3_k127_6891524_18 Ribosome biogenesis protein, C-terminal K09140 - - 0.000000000000000000000000000000000000000000000000000002353 195.0
TLS3_k127_6891524_19 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000007379 198.0
TLS3_k127_6891524_2 Aminotransferase class-V - - - 5.93e-197 619.0
TLS3_k127_6891524_20 Belongs to the SUI1 family K03113 - - 0.000000000000000000000000000000000000000000000000001231 184.0
TLS3_k127_6891524_21 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000005675 187.0
TLS3_k127_6891524_22 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000001873 119.0
TLS3_k127_6891524_23 Rad4 transglutaminase-like domain K01456 GO:0000224,GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006515,GO:0006516,GO:0006517,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009100,GO:0009636,GO:0009719,GO:0009725,GO:0009751,GO:0009987,GO:0010033,GO:0010035,GO:0010188,GO:0010193,GO:0014070,GO:0016787,GO:0016810,GO:0016811,GO:0019538,GO:0030163,GO:0036211,GO:0042221,GO:0042493,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051603,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1901700 3.5.1.52 0.000000000000000000000000000144 124.0
TLS3_k127_6891524_24 - - - - 0.0000000000000000000000000013 113.0
TLS3_k127_6891524_25 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.00000000000000000000008205 98.0
TLS3_k127_6891524_26 Sec61beta family - - - 0.000000000000000000006889 93.0
TLS3_k127_6891524_27 - - - - 0.00000000000000000001615 91.0
TLS3_k127_6891524_28 RNA-binding protein contains TRAM domain - - - 0.0000000000000000005736 89.0
TLS3_k127_6891524_3 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 608.0
TLS3_k127_6891524_30 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) K07143 - - 0.00000001183 63.0
TLS3_k127_6891524_4 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 580.0
TLS3_k127_6891524_5 Type III restriction enzyme, res subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 456.0
TLS3_k127_6891524_6 Predicted membrane protein (DUF2070) K08979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 459.0
TLS3_k127_6891524_7 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 423.0
TLS3_k127_6891524_8 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 413.0
TLS3_k127_6891524_9 Belongs to the peptidase M24B family K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 372.0
TLS3_k127_6898254_0 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000037 139.0
TLS3_k127_6898254_1 cheY-homologous receiver domain - - - 0.0007487 45.0
TLS3_k127_6907060_0 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009479 400.0
TLS3_k127_6907060_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000001167 240.0
TLS3_k127_6907060_2 PFAM NHL repeat containing protein - - - 0.0000000000000000000000005133 107.0
TLS3_k127_6907060_3 Alpha/beta hydrolase family - - - 0.000000000000000000003445 96.0
TLS3_k127_6907060_4 - - - - 0.000000000000005741 89.0
TLS3_k127_6907060_5 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.000000000005922 70.0
TLS3_k127_6907060_6 - - - - 0.00000000004453 72.0
TLS3_k127_6907060_7 Integrase core domain - - - 0.000000004898 63.0
TLS3_k127_6907060_8 Zinc-dependent metalloprotease - - - 0.000001817 57.0
TLS3_k127_6916286_0 thymidylate kinase K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000002135 214.0
TLS3_k127_6916286_1 - - - - 0.000000000000000000000000000000000000003207 150.0
TLS3_k127_6923053_0 Alpha mannosidase, middle domain K01191 - 3.2.1.24 1.195e-236 760.0
TLS3_k127_6923053_1 Hydrolyzes mannosyl-3-phosphoglycerate (MPG) to form the osmolyte mannosylglycerate (MG) K07026 - 3.1.3.70 0.0000000000000000000000000000000000000000000000004101 186.0
TLS3_k127_6923053_2 elongation factor Tu - - - 0.0000000000000000000000000000000000001187 145.0
TLS3_k127_6938310_0 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000004658 126.0
TLS3_k127_6938310_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000001379 119.0
TLS3_k127_6938310_2 Protein of unknown function (DUF4242) - - - 0.00000000000000000001393 93.0
TLS3_k127_6938310_3 Collagen triple helix repeat (20 copies) - - - 0.000000000006713 75.0
TLS3_k127_6942569_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 316.0
TLS3_k127_6942569_1 beta-1,4-mannooligosaccharide phosphorylase - - - 0.000000000000000000000000000000000000000000000000000000000000000394 232.0
TLS3_k127_6942569_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000001886 149.0
TLS3_k127_6942569_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000008846 76.0
TLS3_k127_6949662_0 Radical SAM - - - 8.3e-321 984.0
TLS3_k127_6949662_1 FeS assembly protein SufB K09014 - - 8.005e-280 863.0
TLS3_k127_6949662_10 FeS assembly protein SufD K09014,K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 554.0
TLS3_k127_6949662_100 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.0000000000000000000000000000000001083 134.0
TLS3_k127_6949662_101 - - - - 0.0000000000000000000000000000000002458 134.0
TLS3_k127_6949662_102 NUDIX domain - - - 0.000000000000000000000000000000001901 135.0
TLS3_k127_6949662_104 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.000000000000000000000000000004725 119.0
TLS3_k127_6949662_106 - - - - 0.00000000000000000000000000001253 123.0
TLS3_k127_6949662_107 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.00000000000000000000000000006312 119.0
TLS3_k127_6949662_108 - - - - 0.000000000000000000000000001968 113.0
TLS3_k127_6949662_109 Putative tRNA binding domain K06878 - - 0.0000000000000000000000000137 112.0
TLS3_k127_6949662_11 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 552.0
TLS3_k127_6949662_110 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.00000000000000000000000002236 112.0
TLS3_k127_6949662_112 - - - - 0.000000000000000000000003627 111.0
TLS3_k127_6949662_113 - - - - 0.000000000000000000000004597 105.0
TLS3_k127_6949662_114 - - - - 0.0000000000000000000001312 102.0
TLS3_k127_6949662_115 - - - - 0.0000000000000000000003886 96.0
TLS3_k127_6949662_116 - - - - 0.00000000000000000001554 95.0
TLS3_k127_6949662_117 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.0000000000000000000271 91.0
TLS3_k127_6949662_118 - - - - 0.00000000000000000003369 91.0
TLS3_k127_6949662_119 metal-dependent protease of the PAD1 JAB1 superfamily K21140 - 3.13.1.6 0.00000000000000000005722 96.0
TLS3_k127_6949662_12 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 549.0
TLS3_k127_6949662_120 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.0000000000000000004516 91.0
TLS3_k127_6949662_121 Cache 3/Cache 2 fusion domain K02482 - 2.7.13.3 0.000000000000002885 81.0
TLS3_k127_6949662_123 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000001952 76.0
TLS3_k127_6949662_124 - - - - 0.0000000001097 66.0
TLS3_k127_6949662_125 IMP dehydrogenase activity - - - 0.0000000002302 63.0
TLS3_k127_6949662_126 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.000000002916 68.0
TLS3_k127_6949662_128 Transcriptional regulator - - - 0.0000002424 55.0
TLS3_k127_6949662_129 Belongs to the complex I 20 kDa subunit family K00331 - 1.6.5.3 0.0000007159 52.0
TLS3_k127_6949662_13 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007742 545.0
TLS3_k127_6949662_14 Isocitrate isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 534.0
TLS3_k127_6949662_15 geranylgeranyl reductase K17830 - 1.3.1.101,1.3.7.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 529.0
TLS3_k127_6949662_16 small GTP-binding protein K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 500.0
TLS3_k127_6949662_17 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005674 487.0
TLS3_k127_6949662_18 PFAM Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 482.0
TLS3_k127_6949662_19 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 478.0
TLS3_k127_6949662_2 DNA Topoisomerase I (eukaryota) K03163 - 5.99.1.2 3.19e-228 719.0
TLS3_k127_6949662_20 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 474.0
TLS3_k127_6949662_21 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 470.0
TLS3_k127_6949662_22 oxidoreductase FAD NAD(P)-binding K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008252 469.0
TLS3_k127_6949662_23 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 465.0
TLS3_k127_6949662_24 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 454.0
TLS3_k127_6949662_25 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 456.0
TLS3_k127_6949662_26 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 449.0
TLS3_k127_6949662_27 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 441.0
TLS3_k127_6949662_28 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 426.0
TLS3_k127_6949662_29 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 424.0
TLS3_k127_6949662_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.571e-224 700.0
TLS3_k127_6949662_30 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 432.0
TLS3_k127_6949662_31 PFAM Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 424.0
TLS3_k127_6949662_32 Radical SAM K11780 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 420.0
TLS3_k127_6949662_33 PFAM regulatory protein, ArsR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000095 426.0
TLS3_k127_6949662_34 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 409.0
TLS3_k127_6949662_35 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 389.0
TLS3_k127_6949662_36 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 365.0
TLS3_k127_6949662_37 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 360.0
TLS3_k127_6949662_38 Belongs to the phosphoglycerate kinase family K00927 GO:0002237,GO:0003674,GO:0003824,GO:0004618,GO:0004672,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005829,GO:0005886,GO:0005911,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006464,GO:0006468,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009314,GO:0009408,GO:0009416,GO:0009506,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009743,GO:0009746,GO:0009749,GO:0009987,GO:0010033,GO:0016020,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0030054,GO:0031090,GO:0032787,GO:0034284,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036211,GO:0042221,GO:0042866,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048046,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051707,GO:0055044,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0098588,GO:0098805,GO:0140096,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901700 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007623 365.0
TLS3_k127_6949662_39 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 354.0
TLS3_k127_6949662_4 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 4.332e-223 700.0
TLS3_k127_6949662_40 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 357.0
TLS3_k127_6949662_41 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 348.0
TLS3_k127_6949662_42 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 342.0
TLS3_k127_6949662_43 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 330.0
TLS3_k127_6949662_44 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 306.0
TLS3_k127_6949662_45 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 310.0
TLS3_k127_6949662_46 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 310.0
TLS3_k127_6949662_47 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 302.0
TLS3_k127_6949662_48 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 291.0
TLS3_k127_6949662_49 F420-0:Gamma-glutamyl ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009005 290.0
TLS3_k127_6949662_5 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 5.328e-216 684.0
TLS3_k127_6949662_50 Belongs to the precorrin methyltransferase family K02303 - 2.1.1.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 288.0
TLS3_k127_6949662_51 Delta-aminolevulinic acid dehydratase K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000273 289.0
TLS3_k127_6949662_52 archaeal coiled-coil protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001874 287.0
TLS3_k127_6949662_53 Siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006361 277.0
TLS3_k127_6949662_54 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001483 284.0
TLS3_k127_6949662_55 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001721 274.0
TLS3_k127_6949662_56 ribosomal protein K02866 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001118 265.0
TLS3_k127_6949662_57 3-isopropylmalate dehydratase, small subunit K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000004064 263.0
TLS3_k127_6949662_58 Protein of unknown function (DUF655) K07572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008932 265.0
TLS3_k127_6949662_59 Amino acid kinase family K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000357 266.0
TLS3_k127_6949662_6 synthetase (class II) K01880 - 6.1.1.14 5.287e-213 671.0
TLS3_k127_6949662_60 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001367 259.0
TLS3_k127_6949662_61 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001901 253.0
TLS3_k127_6949662_62 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000001314 249.0
TLS3_k127_6949662_63 Diphthamide synthase K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000008157 237.0
TLS3_k127_6949662_64 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000053 240.0
TLS3_k127_6949662_65 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000001166 237.0
TLS3_k127_6949662_66 SUF system FeS assembly protein K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000001934 228.0
TLS3_k127_6949662_67 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002587 231.0
TLS3_k127_6949662_68 - - - - 0.000000000000000000000000000000000000000000000000000000000000001829 220.0
TLS3_k127_6949662_69 - - - - 0.00000000000000000000000000000000000000000000000000000000000003511 220.0
TLS3_k127_6949662_7 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.264e-205 649.0
TLS3_k127_6949662_70 - - - - 0.00000000000000000000000000000000000000000000000000000000000008211 216.0
TLS3_k127_6949662_71 - - - - 0.000000000000000000000000000000000000000000000000000000000002103 214.0
TLS3_k127_6949662_72 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 3 K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000008883 205.0
TLS3_k127_6949662_73 - - - - 0.0000000000000000000000000000000000000000000000000000000004416 210.0
TLS3_k127_6949662_74 PBS lyase HEAT-like repeat K06072 - 1.14.99.29 0.000000000000000000000000000000000000000000000000000000002852 203.0
TLS3_k127_6949662_75 Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000001822 206.0
TLS3_k127_6949662_76 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000007691 201.0
TLS3_k127_6949662_77 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.000000000000000000000000000000000000000000000000000008845 195.0
TLS3_k127_6949662_78 Signal peptidase K13280 - 3.4.21.89 0.00000000000000000000000000000000000000000000000001147 185.0
TLS3_k127_6949662_79 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function - - - 0.00000000000000000000000000000000000000000000000002571 187.0
TLS3_k127_6949662_8 Radical SAM K11781 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 569.0
TLS3_k127_6949662_80 Nudix hydrolase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000008579 178.0
TLS3_k127_6949662_81 - - - - 0.000000000000000000000000000000000000000000000008542 174.0
TLS3_k127_6949662_82 AhpC/TSA antioxidant enzyme K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000001081 173.0
TLS3_k127_6949662_83 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000003008 167.0
TLS3_k127_6949662_84 Methyltransferase small domain K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000007073 168.0
TLS3_k127_6949662_85 - - - - 0.0000000000000000000000000000000000000000004025 162.0
TLS3_k127_6949662_86 - - - - 0.000000000000000000000000000000000000000009129 154.0
TLS3_k127_6949662_87 Transcription elongation factor - - - 0.00000000000000000000000000000000000000001443 158.0
TLS3_k127_6949662_88 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000724 157.0
TLS3_k127_6949662_89 glutamine amidotransferase K01951 - 6.3.5.2 0.0000000000000000000000000000000000000009757 154.0
TLS3_k127_6949662_9 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 556.0
TLS3_k127_6949662_91 - - - - 0.00000000000000000000000000000000000001854 152.0
TLS3_k127_6949662_92 Peptidyl-tRNA hydrolase PTH2 K04794 - 3.1.1.29 0.00000000000000000000000000000000000007302 145.0
TLS3_k127_6949662_93 - - - - 0.0000000000000000000000000000000000001872 143.0
TLS3_k127_6949662_94 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.000000000000000000000000000000000002552 151.0
TLS3_k127_6949662_95 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.000000000000000000000000000000000004668 138.0
TLS3_k127_6949662_96 low-complexity proteins - - - 0.000000000000000000000000000000000022 140.0
TLS3_k127_6949662_97 - - - - 0.00000000000000000000000000000000005217 134.0
TLS3_k127_6949662_98 of nitrite reductase and ring-hydroxylating K05710 - - 0.00000000000000000000000000000000006871 135.0
TLS3_k127_6949662_99 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.00000000000000000000000000000000006938 136.0
TLS3_k127_6997016_0 - - - - 0.00000000000000000000000003535 113.0
TLS3_k127_6998094_0 response regulator, receiver - - - 0.0000000000000000006011 92.0
TLS3_k127_6998094_1 - - - - 0.000002199 53.0
TLS3_k127_7035035_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 3.417e-307 956.0
TLS3_k127_7035035_1 NADH ubiquinone oxidoreductase subunit 2 (Chain N) K22169 - 1.5.98.3 4.716e-221 695.0
TLS3_k127_7035035_2 Proton-conducting membrane transporter K00342 - 1.6.5.3 4.786e-197 631.0
TLS3_k127_7035035_3 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 352.0
TLS3_k127_7035035_5 Iron-containing redox enzyme K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000002283 187.0
TLS3_k127_7035035_6 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000006319 184.0
TLS3_k127_7035035_7 NADH ubiquinone oxidoreductase subunit 11 or 4L (chain K) K00340 - 1.6.5.3 0.0000000000000000000000000000000001471 134.0
TLS3_k127_7035035_8 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K05710 - - 0.000000000000000000000000000004424 123.0
TLS3_k127_7035035_9 RNA-binding protein contains TRAM domain - - - 0.000000000000000000009533 97.0
TLS3_k127_7043904_0 Hint domain - - - 0.0000000004339 66.0
TLS3_k127_706822_0 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 439.0
TLS3_k127_706822_1 COG0346 Lactoylglutathione lyase and related lyases K15975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 433.0
TLS3_k127_706822_2 phospholipase Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000005722 220.0
TLS3_k127_706822_3 Nitroreductase - - - 0.0000000000000000000000000000000000000001143 153.0
TLS3_k127_706822_4 Protein of unknown function (DUF1264) - - - 0.0000000000000000003608 94.0
TLS3_k127_706822_6 - - - - 0.0001527 46.0
TLS3_k127_7070394_0 PFAM (2R)-phospho-3-sulfolactate synthase ComA K08097 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 4.4.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 384.0
TLS3_k127_7070394_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 364.0
TLS3_k127_7074681_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000007367 141.0
TLS3_k127_7074681_1 COG3316 Transposase and inactivated derivatives - - - 0.00008544 47.0
TLS3_k127_7087325_0 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 379.0
TLS3_k127_7087325_1 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004296 254.0
TLS3_k127_7090421_0 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002421 278.0
TLS3_k127_7109054_0 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000006343 206.0
TLS3_k127_7109054_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000608 188.0
TLS3_k127_7144502_0 fumarate reductase flavoprotein K00239 - 1.3.5.1,1.3.5.4 1.896e-313 966.0
TLS3_k127_7144502_1 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 2e-285 887.0
TLS3_k127_7144502_10 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000002784 198.0
TLS3_k127_7144502_11 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.000000000000000000000000000000000000000000000000000001922 193.0
TLS3_k127_7144502_12 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000000003308 173.0
TLS3_k127_7144502_13 Glyoxalase-like domain K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000001391 162.0
TLS3_k127_7144502_14 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.0000000000000000000000000000000000000002355 153.0
TLS3_k127_7144502_15 snRNP Sm proteins K04796 - - 0.0000000000000000000000000000000003568 132.0
TLS3_k127_7144502_16 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.000000000000000000000000000008332 119.0
TLS3_k127_7144502_17 Binds to the 23S rRNA K02896 - - 0.00000000000000000000000000004064 117.0
TLS3_k127_7144502_19 Binds to the 23S rRNA K02922 - - 0.000000000000000000000001016 103.0
TLS3_k127_7144502_2 Belongs to the phosphohexose mutase family K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 581.0
TLS3_k127_7144502_20 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000009957 105.0
TLS3_k127_7144502_22 multicopper - - - 0.0000000000006303 70.0
TLS3_k127_7144502_23 - - - - 0.00000000173 70.0
TLS3_k127_7144502_3 Amidohydrolase family K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 569.0
TLS3_k127_7144502_4 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 466.0
TLS3_k127_7144502_5 Formyl transferase K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 415.0
TLS3_k127_7144502_6 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 359.0
TLS3_k127_7144502_7 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000003044 239.0
TLS3_k127_7144502_8 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000613 229.0
TLS3_k127_7144502_9 Ribose 5-phosphate isomerase K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000001036 233.0
TLS3_k127_7168272_0 4Fe-4S binding domain K00338 - 1.6.5.3 0.00000000000000002885 81.0
TLS3_k127_7189627_0 helicase activity K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 603.0
TLS3_k127_7189627_1 NurA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 364.0
TLS3_k127_7189627_2 Trypsin-like serine protease with C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 333.0
TLS3_k127_7189627_3 Subtilase family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 301.0
TLS3_k127_7189627_4 calcium proton exchanger K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007385 288.0
TLS3_k127_7189627_5 Rad50 zinc hook motif K03546 - - 0.000000000000000000000001093 121.0
TLS3_k127_7189627_6 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547,K05970 - 3.1.1.53 0.00000000000000000000001785 114.0
TLS3_k127_7189627_7 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000001639 100.0
TLS3_k127_7189627_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00073 44.0
TLS3_k127_7194798_0 PFAM Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008868 605.0
TLS3_k127_7194798_1 - - - - 0.00000000000000000000000000005561 118.0
TLS3_k127_7194798_2 domain, Protein - - - 0.00000000000000000000000003009 118.0
TLS3_k127_7194798_3 Heavy-metal-associated domain K01533 - 3.6.3.4 0.000000000000000000000000222 107.0
TLS3_k127_7194798_4 PKD domain - - - 0.000000000003314 78.0
TLS3_k127_7194798_5 - - - - 0.0000005604 58.0
TLS3_k127_7200476_0 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 395.0
TLS3_k127_7200476_1 - - - - 0.00005036 45.0
TLS3_k127_7229113_0 PFAM Integrase core domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 302.0
TLS3_k127_7229113_1 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001454 265.0
TLS3_k127_7229113_2 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000001051 61.0
TLS3_k127_7235864_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 349.0
TLS3_k127_7235864_1 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002279 233.0
TLS3_k127_7235864_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000003162 79.0
TLS3_k127_7235864_3 SIR2-like domain - - - 0.0000000000006444 76.0
TLS3_k127_7235864_4 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0001665 45.0
TLS3_k127_727925_0 Archaeal Nre, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 411.0
TLS3_k127_727925_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 337.0
TLS3_k127_727925_2 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000001247 162.0
TLS3_k127_7280216_0 Hemolysin-type calcium-binding - - - 0.000000000000000000000000000009669 128.0
TLS3_k127_7280216_1 - - - - 0.00000000000000000000000000119 128.0
TLS3_k127_7280216_2 acid phosphatase activity K22390 - - 0.0000000000005362 80.0
TLS3_k127_7280216_3 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000001262 57.0
TLS3_k127_7280216_4 Belongs to the peptidase S8 family K01342,K14645 - 3.4.21.62 0.0000009294 58.0
TLS3_k127_72884_0 Polysaccharide deacetylase - - - 0.0000000000001376 81.0
TLS3_k127_72884_1 Concanavalin A-like lectin/glucanases superfamily - - - 0.0006472 48.0
TLS3_k127_7325567_0 Anticodon-binding domain of tRNA K01873 - 6.1.1.9 0.0 1145.0
TLS3_k127_7325567_1 PFAM Alcohol dehydrogenase GroES-like domain - - - 9.556e-196 614.0
TLS3_k127_7325567_10 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 323.0
TLS3_k127_7325567_11 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 310.0
TLS3_k127_7325567_12 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 308.0
TLS3_k127_7325567_13 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 297.0
TLS3_k127_7325567_14 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 290.0
TLS3_k127_7325567_15 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000501 264.0
TLS3_k127_7325567_16 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001414 239.0
TLS3_k127_7325567_17 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000003934 240.0
TLS3_k127_7325567_18 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000001566 230.0
TLS3_k127_7325567_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000008589 224.0
TLS3_k127_7325567_2 adenylosuccinate lyase K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 571.0
TLS3_k127_7325567_20 UPF0056 membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000697 213.0
TLS3_k127_7325567_21 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.00000000000000000000000000000000000000000000000000000000001339 209.0
TLS3_k127_7325567_22 zinc finger - - - 0.00000000000000000000000000000000000000000000000000000000004187 213.0
TLS3_k127_7325567_23 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 - 2.1.1.260 0.000000000000000000000000000000000000000000000000000000001809 208.0
TLS3_k127_7325567_24 - - - - 0.000000000000000000000000000000000000000000000004954 175.0
TLS3_k127_7325567_25 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091,K01838,K07025 - 3.1.3.18,5.4.2.6 0.00000000000000000000000000000000000000000000002187 178.0
TLS3_k127_7325567_26 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000006478 175.0
TLS3_k127_7325567_27 Binds to the 23S rRNA K02929 - - 0.00000000000000000000000000000000000000000005003 161.0
TLS3_k127_7325567_28 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000008265 167.0
TLS3_k127_7325567_29 - - - - 0.00000000000000000000000000000000000184 147.0
TLS3_k127_7325567_3 aspartate-semialdehyde dehydrogenase K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 560.0
TLS3_k127_7325567_30 CBS domain - - - 0.000000000000000000000000000000000003927 141.0
TLS3_k127_7325567_31 Guanylyl transferase CofC like K14941 - 2.7.7.68 0.00000000000000000000000000000000002811 143.0
TLS3_k127_7325567_32 Belongs to the PDCD5 family K06875 - - 0.000000000000000000000000000000002881 130.0
TLS3_k127_7325567_33 Transcriptional regulator - - - 0.00000000000000000000000000000000306 130.0
TLS3_k127_7325567_34 - - - - 0.0000000000000000000000000000007314 130.0
TLS3_k127_7325567_35 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.0000000000000000000001108 103.0
TLS3_k127_7325567_36 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000000000000000003702 93.0
TLS3_k127_7325567_37 regulatory protein, arsR - - - 0.00000000000000000003814 93.0
TLS3_k127_7325567_38 ribosomal protein K02978 - - 0.0000000000000004317 79.0
TLS3_k127_7325567_39 Chlorophyllase K01061 - 3.1.1.45 0.00000000000003423 73.0
TLS3_k127_7325567_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 472.0
TLS3_k127_7325567_40 Cytidylyltransferase K19712 - 2.7.7.62 0.0000000000004774 78.0
TLS3_k127_7325567_41 tRNA nucleotidyltransferase poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000006674 61.0
TLS3_k127_7325567_42 dienelactone hydrolase K01061 - 3.1.1.45 0.0007747 43.0
TLS3_k127_7325567_5 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 434.0
TLS3_k127_7325567_6 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 397.0
TLS3_k127_7325567_7 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 358.0
TLS3_k127_7325567_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005159 350.0
TLS3_k127_7325567_9 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 321.0
TLS3_k127_7326351_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 2.065e-286 897.0
TLS3_k127_7326351_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 334.0
TLS3_k127_7326351_10 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07478 - - 0.000000000000000000000000000000000000000000000000000004608 196.0
TLS3_k127_7326351_11 HIT domain K02503 - - 0.00000000000000000000000000000000000000000000000006817 182.0
TLS3_k127_7326351_12 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000002644 177.0
TLS3_k127_7326351_13 Cobalamin B12-binding domain protein K16955,K22491 - - 0.00000000000000000000000000000000000000000000004835 179.0
TLS3_k127_7326351_14 Lysine exporter protein LysE YggA - - - 0.000000000000000000000000000000000000000007133 162.0
TLS3_k127_7326351_15 cyclopropane-fatty-acyl-phospholipid synthase K20444 - - 0.0000000000000000000000000000000000000005134 159.0
TLS3_k127_7326351_16 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.0000000000000000000000004742 106.0
TLS3_k127_7326351_17 iron dependent repressor - - - 0.000000000000000000001225 95.0
TLS3_k127_7326351_18 iron dependent repressor - - - 0.000000000000000001357 87.0
TLS3_k127_7326351_19 epimerase dehydratase K07071 - - 0.000000000004315 72.0
TLS3_k127_7326351_2 Trypsin-like serine protease with C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 305.0
TLS3_k127_7326351_20 PFAM response regulator receiver - - - 0.0000000000315 68.0
TLS3_k127_7326351_22 - - - - 0.00000002922 66.0
TLS3_k127_7326351_23 EamA-like transporter family - - - 0.0000002636 62.0
TLS3_k127_7326351_3 COG0455 ATPases involved in chromosome partitioning K03496,K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 299.0
TLS3_k127_7326351_4 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 287.0
TLS3_k127_7326351_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007735 269.0
TLS3_k127_7326351_6 TIGRFAM ParB RepB Spo0J family partition protein K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000002903 244.0
TLS3_k127_7326351_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003643 245.0
TLS3_k127_7326351_8 glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000008382 229.0
TLS3_k127_7326351_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000000000000003085 224.0
TLS3_k127_7403790_0 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 444.0
TLS3_k127_7403790_2 PFAM blue (type 1) copper domain protein - - - 0.0002804 53.0
TLS3_k127_7405299_0 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 301.0
TLS3_k127_7405299_1 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000000000000000002161 147.0
TLS3_k127_7405299_2 Purple acid Phosphatase, N-terminal domain - - - 0.000000000000000000000002357 115.0
TLS3_k127_7434143_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 6.504e-240 764.0
TLS3_k127_7434143_1 glycosyl transferase family K01001 - 2.7.8.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 425.0
TLS3_k127_7506218_0 Lipolytic acyl hydrolase (LAH) - - - 0.0000000000000000000000000000000000001032 143.0
TLS3_k127_7506218_1 lipolytic acyl hydrolase (LAH) - - - 0.00000000000000000000009559 98.0
TLS3_k127_7506218_2 Patatin-like phospholipase - - - 0.0000000000000000000002319 97.0
TLS3_k127_7506218_3 lipolytic acyl hydrolase (LAH) - - - 0.0000000000000000003428 91.0
TLS3_k127_7506218_4 lipolytic acyl hydrolase (LAH) - GO:0001101,GO:0003674,GO:0003824,GO:0004620,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009719,GO:0009725,GO:0009737,GO:0010033,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0033993,GO:0042221,GO:0044424,GO:0044464,GO:0047372,GO:0050896,GO:0052689,GO:0097305,GO:1901700 - 0.00000000000009333 74.0
TLS3_k127_7506218_5 lipolytic acyl hydrolase (LAH) - - - 0.000000000007981 68.0
TLS3_k127_7514841_0 PFAM Iron-containing alcohol dehydrogenase K18602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000582 570.0
TLS3_k127_7514841_1 FAD dependent oxidoreductase K15736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006862 429.0
TLS3_k127_7514841_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 316.0
TLS3_k127_7514841_3 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 330.0
TLS3_k127_7514841_4 Ser thr protein kinase K07176 - - 0.000000000000000000000000000000000000000001036 166.0
TLS3_k127_7514841_5 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000001948 156.0
TLS3_k127_7514841_6 - - - - 0.0000000000000000000000000000000000009578 141.0
TLS3_k127_7552339_0 Protein of unknown function (DUF1264) - - - 0.0000000002473 66.0
TLS3_k127_7552339_1 - - - - 0.00014 47.0
TLS3_k127_7656785_0 Methyltransferase small domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003273 261.0
TLS3_k127_7656785_1 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000888 156.0
TLS3_k127_7656785_2 Phage integrase family - - - 0.000002397 56.0
TLS3_k127_7713807_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1438.0
TLS3_k127_7713807_1 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.194e-228 713.0
TLS3_k127_7713807_2 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 551.0
TLS3_k127_7713807_3 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 554.0
TLS3_k127_7713807_4 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 353.0
TLS3_k127_7713807_5 - - - - 0.000000000000000000000000000000000000000000004172 168.0
TLS3_k127_7713807_6 - - - - 0.0000000000007413 77.0
TLS3_k127_7713807_7 - - - - 0.000001831 55.0
TLS3_k127_7731950_0 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 358.0
TLS3_k127_7731950_1 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000519 198.0
TLS3_k127_7731950_2 CBS domain - - - 0.00000000000000000000000000000000002117 146.0
TLS3_k127_7731950_3 - - - - 0.000000000000000000000003384 117.0
TLS3_k127_7731950_5 PFAM Polysaccharide deacetylase - - - 0.0000000000005289 79.0
TLS3_k127_7731950_6 - - - - 0.0000000000104 70.0
TLS3_k127_7731950_7 Lrp/AsnC ligand binding domain - - - 0.00000000006455 65.0
TLS3_k127_7731950_8 Acetyltransferase (GNAT) domain - - - 0.000001373 57.0
TLS3_k127_7736501_0 Protein of unknown function (DUF3179) - - - 0.0000000000000000000000000000000000000000000001663 170.0
TLS3_k127_7736501_1 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000003537 159.0
TLS3_k127_7736501_2 - - - - 0.000000000000000000000000000000004507 134.0
TLS3_k127_7736501_3 Protein of unknown function (DUF3179) - - - 0.00000000000000000000000000000000946 132.0
TLS3_k127_7736501_4 - - - - 0.00000000000000000000000000006811 129.0
TLS3_k127_7736501_5 Protein of unknown function (DUF3179) - - - 0.00000000000003009 77.0
TLS3_k127_7736501_6 Domain of unknown function (DUF4443) - - - 0.0000000000002549 72.0
TLS3_k127_7736501_7 Antibiotic biosynthesis monooxygenase - - - 0.000000000001324 72.0
TLS3_k127_7748203_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000005808 115.0
TLS3_k127_7748203_1 - - - - 0.0000000000000000000002829 97.0
TLS3_k127_7748203_2 triphosphatase activity K18446 - 3.6.1.25 0.0000000000002254 79.0
TLS3_k127_7748203_3 - - - - 0.0000006759 59.0
TLS3_k127_7750307_0 - - - - 0.00000000000000000000000000000000000000000000000000000000813 203.0
TLS3_k127_7750307_1 Transcriptional regulatory protein, C terminal K18344 - - 0.00000000003768 68.0
TLS3_k127_7750307_2 Hypothetical methyltransferase K14850 - 2.1.1.287 0.00001681 50.0
TLS3_k127_7761943_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 561.0
TLS3_k127_7761943_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 433.0
TLS3_k127_7761943_11 AsnC-type helix-turn-helix domain - - - 0.000000000000000000000000000000000000000001445 158.0
TLS3_k127_7761943_12 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000001629 136.0
TLS3_k127_7761943_14 amidohydrolase - - - 0.000000000000005648 77.0
TLS3_k127_7761943_15 AsnC-type helix-turn-helix domain - - - 0.0000000000007459 69.0
TLS3_k127_7761943_16 GYD domain - - - 0.000000000009499 67.0
TLS3_k127_7761943_17 Alpha/beta hydrolase family - - - 0.00000003408 57.0
TLS3_k127_7761943_18 Bacterial lipoate protein ligase C-terminus K03800 - 6.3.1.20 0.00000005622 57.0
TLS3_k127_7761943_19 - - - - 0.000002203 57.0
TLS3_k127_7761943_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 383.0
TLS3_k127_7761943_20 hydrolase activity, acting on ester bonds - - - 0.000005312 50.0
TLS3_k127_7761943_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0001838,GO:0001841,GO:0001843,GO:0002009,GO:0002237,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006979,GO:0007275,GO:0007399,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009605,GO:0009607,GO:0009617,GO:0009653,GO:0009790,GO:0009792,GO:0009888,GO:0009987,GO:0010033,GO:0010467,GO:0014020,GO:0016053,GO:0016331,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0021915,GO:0031974,GO:0032496,GO:0032501,GO:0032502,GO:0032787,GO:0033993,GO:0034641,GO:0035148,GO:0035239,GO:0035295,GO:0036211,GO:0042221,GO:0043009,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046483,GO:0048598,GO:0048646,GO:0048729,GO:0048731,GO:0048856,GO:0050896,GO:0051186,GO:0051188,GO:0051604,GO:0051704,GO:0051707,GO:0060429,GO:0060562,GO:0060606,GO:0070013,GO:0070283,GO:0071704,GO:0072175,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901700 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 354.0
TLS3_k127_7761943_4 Dihydrolipoyl dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 339.0
TLS3_k127_7761943_5 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 323.0
TLS3_k127_7761943_6 PFAM Alpha beta hydrolase fold-3 domain protein K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 317.0
TLS3_k127_7761943_7 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001254 276.0
TLS3_k127_7761943_8 metal-binding integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002403 258.0
TLS3_k127_7761943_9 Lipoate-protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000008184 233.0
TLS3_k127_7764294_0 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 386.0
TLS3_k127_7764294_1 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 297.0
TLS3_k127_7764294_2 Purple acid Phosphatase, N-terminal domain - - - 0.00000000000000000000000000001876 130.0
TLS3_k127_7764294_3 - - - - 0.0000000000000000000000002604 114.0
TLS3_k127_7764294_4 - - - - 0.00000000000002454 78.0
TLS3_k127_7764294_5 Polysaccharide deacetylase - - - 0.00000000002762 76.0
TLS3_k127_7773304_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 417.0
TLS3_k127_7773304_1 ABC-type transport system, periplasmic component surface lipoprotein K02058,K07335 - - 0.000000002142 59.0
TLS3_k127_7773304_2 ABC-type transport system, periplasmic component surface lipoprotein K02058,K07335 - - 0.000002557 51.0
TLS3_k127_7780028_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 301.0
TLS3_k127_7780028_1 response regulator, receiver - - - 0.00000000000000000000000002068 113.0
TLS3_k127_7780028_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000005058 106.0
TLS3_k127_7780028_3 O-methyltransferase activity K00545 - 2.1.1.6 0.000000000000000000000001953 111.0
TLS3_k127_7780028_5 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000000006405 64.0
TLS3_k127_7780028_7 - - - - 0.000000002358 65.0
TLS3_k127_7780028_8 - - - - 0.000005658 49.0
TLS3_k127_7798360_0 Uncharacterised BCR, YnfA/UPF0060 family K09771 - - 0.00000000000000000000000000000000000000000000000005426 180.0
TLS3_k127_7798360_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000001037 179.0
TLS3_k127_7798360_2 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000002065 167.0
TLS3_k127_7798360_3 PFAM Uncharacterised BCR, YnfA UPF0060 family K09771 - - 0.000000000000000000000000000000000000000002985 158.0
TLS3_k127_7798360_4 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000000000000000001712 148.0
TLS3_k127_7798360_5 F5/8 type C domain - - - 0.0000000000000000000000001067 120.0
TLS3_k127_7798360_6 - - - - 0.00000000000000000000001818 103.0
TLS3_k127_7798360_7 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000008009 87.0
TLS3_k127_7798360_8 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000003398 79.0
TLS3_k127_7798360_9 DUF72 domain containing protein - - - 0.000004839 50.0
TLS3_k127_7810656_0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 - 3.3.1.1 3.595e-202 636.0
TLS3_k127_7810656_1 calcium- and calmodulin-responsive adenylate cyclase activity K01406 - 3.4.24.40 0.000000002118 62.0
TLS3_k127_7814870_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000291 213.0
TLS3_k127_7814870_1 exo-alpha-(2->6)-sialidase activity - - - 0.000741 49.0
TLS3_k127_7817276_0 PAC2 family K06869 - - 0.000000000000000000000000000000000000000000000000000000000000000001662 234.0
TLS3_k127_7817276_1 Purple acid Phosphatase, N-terminal domain - - - 0.000000000000000000000000129 123.0
TLS3_k127_7817276_2 Conserved repeat domain - - - 0.00000000003097 76.0
TLS3_k127_7832568_0 Sodium hydrogen exchanger K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000973 501.0
TLS3_k127_7832568_1 - - - - 0.00000000000000000000000003145 113.0
TLS3_k127_7832568_2 - - - - 0.00000000000004408 79.0
TLS3_k127_7832568_3 COG1525 Micrococcal nuclease (thermonuclease) homologs K01174 - 3.1.31.1 0.000000007125 58.0
TLS3_k127_7832568_4 - - - - 0.000000009583 61.0
TLS3_k127_7832568_5 Putative antitoxin - - - 0.000002321 50.0
TLS3_k127_7838452_0 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 357.0
TLS3_k127_7838452_1 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000001125 196.0
TLS3_k127_7838452_2 - - - - 0.0000000000000003712 83.0
TLS3_k127_7885043_0 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008426 338.0
TLS3_k127_7885043_1 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000004473 237.0
TLS3_k127_7885043_2 TIGRFAM ABC transporter, substrate-binding protein, aliphatic sulfonates family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000009572 225.0
TLS3_k127_7885043_3 PFAM (2R)-phospho-3-sulfolactate synthase ComA K08097 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 4.4.1.19 0.000000000000000000000000000000000000000000000000000000000000004725 228.0
TLS3_k127_7885043_4 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00005738 49.0
TLS3_k127_7892348_0 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 443.0
TLS3_k127_7892348_1 Universal stress protein - - - 0.0000000000000000000000000000000329 130.0
TLS3_k127_7893039_0 - - - - 0.0000000000000000000000000001875 118.0
TLS3_k127_7944412_0 Zinc-binding dehydrogenase K13979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 499.0
TLS3_k127_7944412_1 Belongs to the arginase family K01476 - 3.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 392.0
TLS3_k127_7944412_10 Flavin reductase like domain - - - 0.0000000000000000000006731 102.0
TLS3_k127_7944412_11 - - - - 0.00000000000000001225 87.0
TLS3_k127_7944412_13 Transcriptional regulator - - - 0.000000000000001137 83.0
TLS3_k127_7944412_15 alpha/beta hydrolase fold - - - 0.00000000006702 68.0
TLS3_k127_7944412_16 Activator of Hsp90 ATPase - - - 0.000000004353 59.0
TLS3_k127_7944412_18 glyoxalase III activity - - - 0.0005673 46.0
TLS3_k127_7944412_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 361.0
TLS3_k127_7944412_3 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 330.0
TLS3_k127_7944412_4 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 307.0
TLS3_k127_7944412_6 Nudix hydrolase K03574 - 3.6.1.55 0.000000000000000000000000000000000000000007922 158.0
TLS3_k127_7944412_7 Major Facilitator Superfamily - - - 0.000000000000000000000000000007288 122.0
TLS3_k127_7944412_8 regulatory protein, arsR - - - 0.0000000000000000000000000006991 115.0
TLS3_k127_7944412_9 - - - - 0.0000000000000000000000000007509 119.0
TLS3_k127_7950669_0 Heat shock 70 kDa protein K04043 - - 2.252e-313 969.0
TLS3_k127_7950669_1 Sulfite reductase K00392 - 1.8.7.1 3.01e-285 886.0
TLS3_k127_7950669_10 Sodium hydrogen exchanger K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 463.0
TLS3_k127_7950669_11 tRNA pseudouridine synthase K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 439.0
TLS3_k127_7950669_12 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 409.0
TLS3_k127_7950669_13 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 402.0
TLS3_k127_7950669_14 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 405.0
TLS3_k127_7950669_15 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 392.0
TLS3_k127_7950669_16 PFAM 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 325.0
TLS3_k127_7950669_17 ATP synthase (C/AC39) subunit K02119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 327.0
TLS3_k127_7950669_18 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 322.0
TLS3_k127_7950669_19 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000135 274.0
TLS3_k127_7950669_2 ABC1 family - - - 3.341e-205 650.0
TLS3_k127_7950669_20 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000001377 255.0
TLS3_k127_7950669_21 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005904 261.0
TLS3_k127_7950669_22 Translation initiation factor K03238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003256 248.0
TLS3_k127_7950669_23 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000001468 251.0
TLS3_k127_7950669_24 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.000000000000000000000000000000000000000000000000000000000002741 213.0
TLS3_k127_7950669_25 - - - - 0.0000000000000000000000000000000000000000000000000000000000401 216.0
TLS3_k127_7950669_26 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000007972 192.0
TLS3_k127_7950669_27 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000119 191.0
TLS3_k127_7950669_28 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000000000000002732 184.0
TLS3_k127_7950669_29 Patch-forming domain C2 of tRNA-guanine transglycosylase K07398 - - 0.00000000000000000000000000000000000000000000000007493 181.0
TLS3_k127_7950669_3 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 584.0
TLS3_k127_7950669_31 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000000000000000000000000000000006569 173.0
TLS3_k127_7950669_32 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000002362 177.0
TLS3_k127_7950669_33 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000002998 164.0
TLS3_k127_7950669_34 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.0000000000000000000000000000000000000000001054 163.0
TLS3_k127_7950669_35 - - - - 0.000000000000000000000000000000000000005819 149.0
TLS3_k127_7950669_36 Belongs to the small heat shock protein (HSP20) family - - - 0.00000000000000000000000000000000000001968 147.0
TLS3_k127_7950669_37 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000000009694 143.0
TLS3_k127_7950669_38 transcription factor, homolog of eukaryotic MBF1 K03627 - - 0.00000000000000000000000000000002858 131.0
TLS3_k127_7950669_39 - - - - 0.00000000000000000000000000003653 122.0
TLS3_k127_7950669_4 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006456 580.0
TLS3_k127_7950669_40 H subunit K02107 - - 0.0000000000000000004672 91.0
TLS3_k127_7950669_41 PQ loop repeat - - - 0.00000000001995 68.0
TLS3_k127_7950669_5 DnaJ central domain K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 510.0
TLS3_k127_7950669_6 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 498.0
TLS3_k127_7950669_7 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 478.0
TLS3_k127_7950669_8 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 471.0
TLS3_k127_7950669_9 Glucose sorbosone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 461.0
TLS3_k127_8009247_1 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000003242 160.0
TLS3_k127_8009247_2 Histidine kinase-like ATPases K07677,K07679,K13924,K20974 - 2.1.1.80,2.7.13.3,3.1.1.61 0.000000000000000006558 88.0
TLS3_k127_8009247_3 PFAM response regulator receiver - - - 0.000000000002869 72.0
TLS3_k127_8021786_0 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009277 452.0
TLS3_k127_8021786_1 alpha/beta hydrolase fold - - - 0.00000000136 59.0
TLS3_k127_8096773_0 Histidine kinase A domain protein - - - 0.0000543 48.0
TLS3_k127_8096773_1 Transcriptional regulator - - - 0.0007747 43.0
TLS3_k127_8103113_0 Type III restriction enzyme, res subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009558 471.0
TLS3_k127_8103113_1 N-terminal domain of oxidoreductase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 424.0
TLS3_k127_8103113_10 Protein tyrosine kinase - - - 0.0000000000004653 76.0
TLS3_k127_8103113_11 Flavin reductase like domain - - - 0.0000001287 57.0
TLS3_k127_8103113_12 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.000003062 52.0
TLS3_k127_8103113_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 370.0
TLS3_k127_8103113_3 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 378.0
TLS3_k127_8103113_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000001577 241.0
TLS3_k127_8103113_5 PFAM PQQ enzyme repeat - - - 0.0000000000000000000000000000000000000000315 167.0
TLS3_k127_8103113_6 Belongs to the arginase family K01476 - 3.5.3.1 0.00000000000000000000005779 100.0
TLS3_k127_8103113_7 Uncharacterized conserved protein (DUF2196) - - - 0.000000000000000005991 84.0
TLS3_k127_8103113_8 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000002981 88.0
TLS3_k127_8104282_0 cell adhesion involved in biofilm formation - - - 0.0000000000001119 80.0
TLS3_k127_8104282_1 - - - - 0.00000000003479 70.0
TLS3_k127_8104282_2 - - - - 0.0000001005 55.0
TLS3_k127_8105941_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 565.0
TLS3_k127_8105941_1 Cupredoxin-like domain - - - 0.000000000000000000000000000000002615 135.0
TLS3_k127_8105941_2 - - - - 0.0000000000000000000000000004696 117.0
TLS3_k127_8105941_3 Winged helix-turn-helix - - - 0.000000000000000000001064 96.0
TLS3_k127_8105941_4 Transcriptional regulator - - - 0.00000000000002418 73.0
TLS3_k127_8119148_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 1.725e-220 707.0
TLS3_k127_8119148_1 flavodoxin nitric oxide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000002442 228.0
TLS3_k127_8119148_10 - - - - 0.0000005163 55.0
TLS3_k127_8119148_2 Protocatechuate 3,4-dioxygenase beta subunit - - - 0.0000000000000000000000000000009855 125.0
TLS3_k127_8119148_3 flavodoxin nitric oxide synthase - - - 0.00000000000000000000002826 99.0
TLS3_k127_8119148_4 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00000000000000006177 87.0
TLS3_k127_8119148_5 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0000000000000002735 87.0
TLS3_k127_8119148_6 Transcriptional regulator - - - 0.0000000000000004667 81.0
TLS3_k127_8119148_7 - - - - 0.000000000000002394 81.0
TLS3_k127_8119148_8 - - - - 0.00000000000315 70.0
TLS3_k127_8119148_9 - - - - 0.000000001436 68.0
TLS3_k127_8120606_0 pyridine nucleotide-disulphide oxidoreductase dimerisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 364.0
TLS3_k127_8120606_1 Amino acid synthesis - - - 0.000000000000000000000000000000000000000000000000000000000008679 212.0
TLS3_k127_8120606_2 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000006695 161.0
TLS3_k127_8120606_3 OsmC-like protein - - - 0.00000000000000000000000000915 116.0
TLS3_k127_8120606_4 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000001018 81.0
TLS3_k127_8120606_5 CHRD domain - - - 0.00000000000006886 79.0
TLS3_k127_8120606_6 Cytochrome D1 heme domain - - - 0.0000006716 54.0
TLS3_k127_8122487_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 338.0
TLS3_k127_8122487_1 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 287.0
TLS3_k127_8122487_2 - - - - 0.00000000000000000000000001809 117.0
TLS3_k127_8122487_3 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000001098 81.0
TLS3_k127_81538_0 NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic K05577 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.6.5.3 0.0 1035.0
TLS3_k127_81538_1 NDH shuttles electrons from NAD(P)H plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient K05579 GO:0003674,GO:0003824,GO:0003959,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009507,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0016020,GO:0016491,GO:0016651,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035,GO:0055114 1.6.5.3 2.64e-246 762.0
TLS3_k127_81538_2 NDH shuttles electrons from NAD(P)H plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient K05580 GO:0003674,GO:0003824,GO:0003959,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009987,GO:0015979,GO:0016020,GO:0016491,GO:0016651,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 346.0
TLS3_k127_81538_3 NDH shuttles electrons from NAD(P)H plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient K05572 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0015979,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0019866,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0055114,GO:0070469,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 314.0
TLS3_k127_81538_4 NAD(P)H-quinone oxidoreductase subunit 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 306.0
TLS3_k127_81538_5 NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic K05578 GO:0008150,GO:0008152,GO:0009987,GO:0015979,GO:0044237 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 290.0
TLS3_k127_81538_6 30S ribosomal protein S15 K02956 GO:0000312,GO:0000313,GO:0000314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0009507,GO:0009532,GO:0009536,GO:0009547,GO:0009570,GO:0015935,GO:0032991,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000005177 135.0
TLS3_k127_81538_7 Carboxyl transferase domain K01963,K02696 - 2.1.3.15,6.4.1.2 0.000000000000009979 83.0
TLS3_k127_8263838_0 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000208 195.0
TLS3_k127_8263838_1 Rhodanese Homology Domain - - - 0.00000000000000000000000000000009898 137.0
TLS3_k127_8263838_2 - - - - 0.00000000000000000000000000522 118.0
TLS3_k127_8263838_3 Protein of unknown function (DUF1264) - - - 0.000000000000004601 78.0
TLS3_k127_8263966_0 Sodium:sulfate symporter transmembrane region K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 571.0
TLS3_k127_8263966_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.000000000000000008435 87.0
TLS3_k127_8279084_0 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000001402 200.0
TLS3_k127_8279084_1 Protein of unknown function (DUF4242) - - - 0.000000007352 56.0
TLS3_k127_8338210_1 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000003238 162.0
TLS3_k127_8338210_2 GYD domain - - - 0.0000000000000000000000003577 107.0
TLS3_k127_8338210_3 Domain of unknown function (DUF202) K00389 - - 0.00000000000000000000002233 104.0
TLS3_k127_8338210_4 response regulator, receiver - - - 0.000000000006159 71.0
TLS3_k127_8338210_5 PFAM CBS domain - - - 0.000004312 59.0
TLS3_k127_8346826_0 Phage integrase family - - - 0.00000000000000005351 95.0
TLS3_k127_8380711_0 N-methylhydantoinase A acetone carboxylase, beta subunit - - - 4.262e-284 888.0
TLS3_k127_8380711_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 8.966e-226 711.0
TLS3_k127_8380711_10 RNA methylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003452 252.0
TLS3_k127_8380711_11 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000006482 179.0
TLS3_k127_8380711_12 Pyridine nucleotide-disulphide oxidoreductase K03885 GO:0003674,GO:0003824,GO:0003955,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 1.6.99.3 0.00000000000000000000000000000000000000000000001876 185.0
TLS3_k127_8380711_13 gamma-carboxymuconolactone decarboxylase subunit K01607 - 4.1.1.44 0.000000000000000000000000000000000000001441 151.0
TLS3_k127_8380711_14 - - - - 0.000000000000000000000000000000000000003512 152.0
TLS3_k127_8380711_15 Acetyltransferase (GNAT) domain K00621 - 2.3.1.4 0.00000000000000000000000000002368 123.0
TLS3_k127_8380711_16 Transcriptional regulator - - - 0.0000000000000005129 80.0
TLS3_k127_8380711_2 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007978 490.0
TLS3_k127_8380711_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 396.0
TLS3_k127_8380711_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 372.0
TLS3_k127_8380711_5 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 357.0
TLS3_k127_8380711_6 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 298.0
TLS3_k127_8380711_7 Ribose-phosphate pyrophosphokinase K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001505 283.0
TLS3_k127_8380711_8 Asp/Glu/Hydantoin racemase K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001114 280.0
TLS3_k127_8380711_9 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000006864 266.0
TLS3_k127_8398889_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002506 276.0
TLS3_k127_8398889_1 PFAM regulatory protein TetR K03577,K18939 - - 0.000000000000000000000000000000000001905 145.0
TLS3_k127_8398889_2 PFAM Hemolysin-type calcium-binding - - - 0.000000000000000000000000000000000002188 148.0
TLS3_k127_8411835_0 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 386.0
TLS3_k127_8411835_1 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000001091 212.0
TLS3_k127_8411835_2 Calcineurin-like phosphoesterase - - - 0.0000000000000002747 91.0
TLS3_k127_8411835_3 - - - - 0.000000000004869 70.0
TLS3_k127_8468846_0 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002474 293.0
TLS3_k127_8468846_1 Glycosyltransferase Family 4 - - - 0.00000000000000005746 94.0
TLS3_k127_8532736_0 Probable cobalt transporter subunit (CbtA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002352 259.0
TLS3_k127_8532736_1 Domain of unknown function (DUF4443) - - - 0.000000000000000000000000000000000000000000000000000000000001273 215.0
TLS3_k127_8532736_2 Probable cobalt transporter subunit (CbtB) - - - 0.000000000000000000002426 94.0
TLS3_k127_8532736_3 COG3316 Transposase and inactivated derivatives - - - 0.000000001992 66.0
TLS3_k127_8542169_0 TIGRFAM ABC transporter, substrate-binding protein, aliphatic sulfonates family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 441.0
TLS3_k127_8542169_1 PFAM (2R)-phospho-3-sulfolactate synthase ComA K08097 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 4.4.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 381.0
TLS3_k127_8542169_2 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 337.0
TLS3_k127_8542169_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001469 264.0
TLS3_k127_8542169_4 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049,K10831,K15555 - 3.6.3.36 0.000000000000000000000000000000000000000000000000000000000000000002827 234.0
TLS3_k127_8542169_5 Alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000002799 216.0
TLS3_k127_8542169_6 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000002905 130.0
TLS3_k127_8542169_7 PFAM (2R)-phospho-3-sulfolactate synthase ComA K08097 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 4.4.1.19 0.0007936 44.0
TLS3_k127_8542777_0 ATP-dependent Clp protease proteolytic subunit K01358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 3.4.21.92 0.0000000000000000000000000000000000000000001175 167.0
TLS3_k127_8544272_0 Multicopper oxidase type - - - 1.202e-247 795.0
TLS3_k127_8544272_1 Mg2 transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 361.0
TLS3_k127_8544272_2 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006146 280.0
TLS3_k127_8544272_3 Sulfite exporter TauE/SafE K07090 - - 0.00000009584 54.0
TLS3_k127_8554638_0 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 313.0
TLS3_k127_8554638_1 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 293.0
TLS3_k127_8554638_2 ABC 3 transport family K02075,K09816,K09819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000241 254.0
TLS3_k127_8554638_3 PFAM ABC transporter K09820,K11603 - - 0.000000000000000000000000000000000000000000000000000000000006572 215.0
TLS3_k127_8573390_0 Transcriptional regulator - - - 0.0000000000013 70.0
TLS3_k127_8573390_1 Transcriptional regulator - - - 0.0000003779 53.0
TLS3_k127_8573390_2 phosphatase activity - - - 0.0007658 47.0
TLS3_k127_929665_0 Sodium:sulfate symporter transmembrane region K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006697 557.0
TLS3_k127_929665_1 Peptidase family M1 domain K01256,K13722 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 532.0
TLS3_k127_929665_2 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 302.0
TLS3_k127_929665_3 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000002252 180.0
TLS3_k127_929665_4 - - - - 0.00000000000000000000000004911 121.0
TLS3_k127_933223_0 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000000212 131.0
TLS3_k127_933223_1 Ferredoxin - - - 0.00000000000000000000000007001 111.0
TLS3_k127_941187_0 Pyridine nucleotide-disulphide oxidoreductase K00384,K03387 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 490.0
TLS3_k127_941187_1 integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000007677 228.0
TLS3_k127_941187_10 - - - - 0.00000005426 64.0
TLS3_k127_941187_2 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000009038 225.0
TLS3_k127_941187_3 PPIC-type PPIASE domain K07533 - 5.2.1.8 0.00000000000000000000000000000000000000701 146.0
TLS3_k127_941187_4 Belongs to the FPG family K05522 - 4.2.99.18 0.0000000000000000000000000000000374 136.0
TLS3_k127_941187_6 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000003482 93.0
TLS3_k127_941187_7 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000004646 68.0
TLS3_k127_941187_8 - - - - 0.000000000005479 70.0
TLS3_k127_941187_9 Phage integrase family - - - 0.00000000003567 75.0
TLS3_k127_950676_0 PFAM TCP-1 cpn60 chaperonin family K22447 - - 3.369e-225 706.0
TLS3_k127_950676_1 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 368.0
TLS3_k127_950676_2 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 348.0
TLS3_k127_950676_3 UreF K03188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002407 255.0
TLS3_k127_950676_4 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000009432 216.0
TLS3_k127_950676_5 UreE urease accessory protein, N-terminal domain K03187 - - 0.00000000000000000000000000000000000007222 148.0
TLS3_k127_950676_7 CHRD domain - - - 0.000000000000000001137 93.0
TLS3_k127_950676_9 Major Facilitator Superfamily - - - 0.000000002898 67.0
TLS3_k127_951392_0 - - - - 0.000000000000000000003853 94.0
TLS3_k127_951392_1 CHRD domain - - - 0.000000000001177 74.0
TLS3_k127_954030_0 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001826 259.0
TLS3_k127_954030_3 Calcineurin-like phosphoesterase - - - 0.0000000607 65.0
TLS3_k127_960610_0 Transcriptional regulator - - - 0.0000000000000001726 82.0
TLS3_k127_960610_1 DsrE/DsrF-like family - - - 0.000001671 55.0
TLS3_k127_960610_2 Cupin domain - - - 0.000005563 50.0
TLS3_k127_963469_0 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000007063 237.0
TLS3_k127_963469_1 Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000002977 152.0
TLS3_k127_963469_2 CBS domain - - - 0.0000001474 61.0
TLS3_k127_963469_3 MgtE intracellular N domain - - - 0.000078 52.0
TLS3_k127_969778_0 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000002209 163.0
TLS3_k127_969778_1 Methionine biosynthesis protein MetW - - - 0.00000072 56.0
TLS3_k127_993257_0 RNA-metabolising metallo-beta-lactamase K07041 - - 0.0 1020.0
TLS3_k127_993257_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 2.432e-237 741.0
TLS3_k127_993257_10 Phosphomethylpyrimidine kinase K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 400.0
TLS3_k127_993257_11 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008311 353.0
TLS3_k127_993257_12 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 330.0
TLS3_k127_993257_13 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 317.0
TLS3_k127_993257_14 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 303.0
TLS3_k127_993257_15 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000004281 268.0
TLS3_k127_993257_16 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000002611 257.0
TLS3_k127_993257_17 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000000003745 259.0
TLS3_k127_993257_18 segregation and condensation protein K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000007716 231.0
TLS3_k127_993257_19 - - - - 0.000000000000000000000000000000000000000000000000000000000001625 218.0
TLS3_k127_993257_2 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 619.0
TLS3_k127_993257_20 chromosome segregation and condensation protein ScpA K05896 - - 0.00000000000000000000000000000000000000000000000000000000001576 213.0
TLS3_k127_993257_21 Functions by promoting the formation of the first peptide bond K03263 - - 0.000000000000000000000000000000000000000000000000000000003911 202.0
TLS3_k127_993257_22 K homology RNA-binding domain K06961 - - 0.0000000000000000000000000000000000000000000000000000001764 199.0
TLS3_k127_993257_23 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000007872 184.0
TLS3_k127_993257_24 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000001994 173.0
TLS3_k127_993257_25 Ribosomal protein S8e K02995 - - 0.0000000000000000000000000000000000000000001391 162.0
TLS3_k127_993257_26 - - - - 0.0000000000000000000000000000000000000000005066 168.0
TLS3_k127_993257_27 DnaJ molecular chaperone homology domain K03686 - - 0.0000000000000000000000000000000000000002478 153.0
TLS3_k127_993257_28 ATP synthase (F/14-kDa) subunit K02122 - - 0.00000000000000000000000000000000003825 136.0
TLS3_k127_993257_29 ferredoxin - - - 0.000000000000000000000000000000004809 132.0
TLS3_k127_993257_3 Cysteine synthase K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 527.0
TLS3_k127_993257_30 - - - - 0.0000000000000000000000000000008343 124.0
TLS3_k127_993257_31 redox protein, regulator of disulfide bond formation - - - 0.000000000000000000000000000002219 122.0
TLS3_k127_993257_32 SRP19 protein K03105 - - 0.00000000000000000000000000001254 120.0
TLS3_k127_993257_33 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03014 - - 0.0000000000000000000000000004287 120.0
TLS3_k127_993257_34 Bacterial Fe(2+) trafficking - - - 0.0000000000000000000000002169 108.0
TLS3_k127_993257_35 Cyclophilin-like K09143 - - 0.000000000000000000003841 97.0
TLS3_k127_993257_36 Protein of unknown function (DUF424) K09148 - - 0.0000000000000000002769 93.0
TLS3_k127_993257_38 S25 ribosomal protein K02975 - - 0.000000000000003414 79.0
TLS3_k127_993257_39 RNA-binding protein involved in rRNA processing K07569 - - 0.00000000000002871 76.0
TLS3_k127_993257_4 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 490.0
TLS3_k127_993257_40 Zinc finger, C2H2 type - - - 0.0000000000006812 72.0
TLS3_k127_993257_41 - - - - 0.000000000104 68.0
TLS3_k127_993257_42 Pfam Glycosyl transferase family 2 - - - 0.000000002435 68.0
TLS3_k127_993257_5 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 482.0
TLS3_k127_993257_6 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 463.0
TLS3_k127_993257_7 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 458.0
TLS3_k127_993257_8 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 424.0
TLS3_k127_993257_9 factor TFIIB K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 416.0