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Overview

ID MAG04049
Name TLS3_bin.26
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Steroidobacterales
Family Steroidobacteraceae
Genus
Species
Assembly information
Completeness (%) 70.53
Contamination (%) 3.36
GC content (%) 61.0
N50 (bp) 6,017
Genome size (bp) 3,703,202

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3264

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1011485_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 478.0
TLS3_k127_1011485_1 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 397.0
TLS3_k127_1015105_0 Belongs to the Orn Lys Arg decarboxylase class-II family K00928,K12526 - 2.7.2.4,4.1.1.20 4.307e-312 978.0
TLS3_k127_1015105_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000001798 130.0
TLS3_k127_1015105_2 ORF6N domain - - - 0.000000000000000000000000000002643 121.0
TLS3_k127_1015105_3 ORF6N domain - - - 0.000001792 50.0
TLS3_k127_1019298_0 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000002315 242.0
TLS3_k127_1019298_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000001121 161.0
TLS3_k127_104628_0 Catalyzes a key regulatory step in fatty acid biosynthesis K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 357.0
TLS3_k127_104628_1 lytic transglycosylase K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 351.0
TLS3_k127_106321_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1176.0
TLS3_k127_106321_1 Belongs to the phospholipase D family. Cardiolipin synthase subfamily K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 316.0
TLS3_k127_106321_2 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 304.0
TLS3_k127_106321_3 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002118 268.0
TLS3_k127_106321_4 - - - - 0.0000003738 56.0
TLS3_k127_1085520_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009004 388.0
TLS3_k127_1087250_0 Single-stranded-DNA-specific exonuclease K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 616.0
TLS3_k127_1087250_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 511.0
TLS3_k127_1087250_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 326.0
TLS3_k127_1087250_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000004234 263.0
TLS3_k127_1087250_4 COG0739 Membrane proteins related to metalloendopeptidases K06194,K12943 GO:0000920,GO:0001896,GO:0005575,GO:0005623,GO:0008150,GO:0008219,GO:0009279,GO:0009987,GO:0012501,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0043085,GO:0044093,GO:0044462,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071944 - 0.00000000000000000000000000000000000000000000000000006086 196.0
TLS3_k127_1087250_5 PFAM Smr - - - 0.0000000000000000000000000000000000000004434 155.0
TLS3_k127_1087250_6 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000004732 121.0
TLS3_k127_1087250_7 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000005086 87.0
TLS3_k127_1087250_8 Protein conserved in bacteria - - - 0.00000000000000008775 92.0
TLS3_k127_1088770_0 - - - - 0.0000000000000000000000000000000008497 134.0
TLS3_k127_1088770_1 PFAM glutathione-dependent formaldehyde-activating - - - 0.000000000000000000003628 95.0
TLS3_k127_1088770_2 B12 binding domain - - - 0.00000000000002747 78.0
TLS3_k127_1100916_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 576.0
TLS3_k127_1100916_1 nuclear-transcribed mRNA catabolic process, no-go decay - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 413.0
TLS3_k127_1100916_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 379.0
TLS3_k127_1100916_3 Threonine transporter RhtB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 329.0
TLS3_k127_1100916_4 Tryptophan-rich sensory protein K05770 - - 0.00000000000000000000000000000000000000000000000000000000000000002576 226.0
TLS3_k127_1100916_5 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000002183 192.0
TLS3_k127_1100916_6 3D domain protein - - - 0.0000000000000000000000000000000001761 137.0
TLS3_k127_1100916_8 Pfam:DUF1049 K08992 - - 0.000006514 53.0
TLS3_k127_1114261_0 His Kinase A (phosphoacceptor) domain K20971 - - 2.992e-287 899.0
TLS3_k127_1114261_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 389.0
TLS3_k127_1114261_2 Cupin 2 conserved barrel domain protein K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000001699 165.0
TLS3_k127_1118257_0 GAF domain K20962 - 3.1.4.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 399.0
TLS3_k127_1118257_1 BON domain - - - 0.00000000000000000000000000000000000000000000000000000000000009023 220.0
TLS3_k127_1118257_2 cheY-homologous receiver domain - - - 0.00000000000000000000000000001525 122.0
TLS3_k127_1126376_0 Molecular chaperone. Has ATPase activity K04079 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006974,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0042623,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 - 3.288e-250 786.0
TLS3_k127_1126376_1 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 614.0
TLS3_k127_1126376_2 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 614.0
TLS3_k127_1126376_3 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000504 276.0
TLS3_k127_1126376_4 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008573 258.0
TLS3_k127_1126376_5 - - - - 0.00000000000000000000000000000000000000000000000003831 196.0
TLS3_k127_1126376_6 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000003952 166.0
TLS3_k127_1126376_7 PEP-CTERM motif - - - 0.00000000000000000000000000000000000408 146.0
TLS3_k127_1126376_8 regulation of single-species biofilm formation - - - 0.00000000000000001483 85.0
TLS3_k127_1129167_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 8.135e-265 820.0
TLS3_k127_1129167_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.092e-259 807.0
TLS3_k127_1129167_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000000000000000000001339 171.0
TLS3_k127_1129167_3 - - GO:0008150,GO:0009605,GO:0009607,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 - 0.00000000000004535 74.0
TLS3_k127_1139255_0 Peptidase M16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 528.0
TLS3_k127_1139255_1 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 429.0
TLS3_k127_1139255_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007941 301.0
TLS3_k127_1139255_3 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000007482 63.0
TLS3_k127_114182_0 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 527.0
TLS3_k127_114182_1 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 464.0
TLS3_k127_114182_2 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 404.0
TLS3_k127_114182_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000002576 156.0
TLS3_k127_114182_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000113 116.0
TLS3_k127_114182_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000119 74.0
TLS3_k127_1143438_0 trisaccharide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000739 625.0
TLS3_k127_1143438_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000375 281.0
TLS3_k127_1145534_0 PFAM Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 582.0
TLS3_k127_1145534_1 PFAM Beta-lactamase - - - 0.000000006667 63.0
TLS3_k127_1148050_0 Anthranilate synthase component I, N terminal region K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 322.0
TLS3_k127_1148050_1 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000001862 256.0
TLS3_k127_1148050_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000002432 258.0
TLS3_k127_115042_0 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 565.0
TLS3_k127_115042_1 Subtilase family K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008437 424.0
TLS3_k127_1161266_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 2.426e-302 945.0
TLS3_k127_1161266_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 382.0
TLS3_k127_1161266_2 COG4767 Glycopeptide antibiotics resistance protein - - - 0.0000000000000000000000000000001811 138.0
TLS3_k127_1161266_3 TrkA-N domain K03499 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0015075,GO:0015672,GO:0016020,GO:0022857,GO:0030001,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0098655 - 0.0000000000001519 71.0
TLS3_k127_1161266_4 membrane K08985 - - 0.000000000004777 76.0
TLS3_k127_1162865_0 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000002286 239.0
TLS3_k127_1162865_1 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.00000000000000000000000000000000000000000000000000000001934 203.0
TLS3_k127_1162865_2 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000003848 117.0
TLS3_k127_1162865_3 response regulator - - - 0.0000000000000002308 85.0
TLS3_k127_1162865_4 Sigma-54 interaction domain - - - 0.0000000000004547 74.0
TLS3_k127_1162865_5 Domain of unknown function (DUF4142) K08995 - - 0.000000000001276 76.0
TLS3_k127_1162865_6 Protein required for attachment to host cells - - - 0.000000000001529 73.0
TLS3_k127_1171452_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 2.5e-323 1000.0
TLS3_k127_1171452_1 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 308.0
TLS3_k127_1171452_2 TIGRFAM Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.0000000000000000000000000000000000000189 149.0
TLS3_k127_1176272_0 General secretion pathway protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 438.0
TLS3_k127_1176272_1 EamA-like transporter family K15268 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002439 263.0
TLS3_k127_1176272_2 Cytosol aminopeptidase family, catalytic domain K01255 - 3.4.11.1 0.000000000000000000000000000000000009673 137.0
TLS3_k127_1181062_0 Protein conserved in bacteria - - - 2.612e-209 666.0
TLS3_k127_1181062_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000001176 213.0
TLS3_k127_1181062_2 - - - - 0.0000000000000000000000000000000000000000001723 163.0
TLS3_k127_1181062_3 Inner membrane component of T3SS, cytoplasmic domain K01990,K21397 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030312,GO:0031224,GO:0042623,GO:0042626,GO:0043492,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000001132 80.0
TLS3_k127_1182615_0 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.0000000000000000000000000000000000000000000000000000000000000000001227 236.0
TLS3_k127_1182615_1 L-glyceraldehyde 3-phosphate reductase K19265 - - 0.0000000000000000000000000000000000000000000003155 170.0
TLS3_k127_1182615_2 Bacterial PH domain - - - 0.000000000000000000000000002134 118.0
TLS3_k127_1182615_3 - - - - 0.00000000000007598 78.0
TLS3_k127_1183217_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 3.556e-204 644.0
TLS3_k127_1183217_1 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 420.0
TLS3_k127_1183217_2 PFAM CBS domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 317.0
TLS3_k127_1183217_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.000000000000000000000000000000000000000000000001204 179.0
TLS3_k127_1183217_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000001188 147.0
TLS3_k127_1186479_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.196e-209 658.0
TLS3_k127_1186479_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.394e-202 640.0
TLS3_k127_1186479_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 519.0
TLS3_k127_1186479_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 398.0
TLS3_k127_1186479_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 339.0
TLS3_k127_1186479_5 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 315.0
TLS3_k127_1186479_6 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000001711 128.0
TLS3_k127_1192184_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.13e-221 698.0
TLS3_k127_1192184_1 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 4.37e-209 661.0
TLS3_k127_1192184_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 584.0
TLS3_k127_1192184_3 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 505.0
TLS3_k127_1192184_4 MlrC C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 444.0
TLS3_k127_1192184_5 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 290.0
TLS3_k127_1192184_6 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000373 239.0
TLS3_k127_1192184_7 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000004579 218.0
TLS3_k127_1209518_0 Putative glutamine amidotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 521.0
TLS3_k127_1209518_1 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 481.0
TLS3_k127_1209518_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 425.0
TLS3_k127_1209518_3 Encapsulating protein for peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008922 329.0
TLS3_k127_1209518_4 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 309.0
TLS3_k127_1209518_5 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000000000000008748 201.0
TLS3_k127_1209518_6 COG0583 Transcriptional regulator K03566 - - 0.0000000000000000000000000000000000000000000000719 183.0
TLS3_k127_1209518_7 Evidence 4 Homologs of previously reported genes of K09700 - - 0.00000000000000000000000000000000000007623 149.0
TLS3_k127_1212107_0 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 547.0
TLS3_k127_1212107_1 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 326.0
TLS3_k127_1218553_0 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 513.0
TLS3_k127_1218553_1 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000003988 56.0
TLS3_k127_1221428_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000485 188.0
TLS3_k127_1221428_1 MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000001321 167.0
TLS3_k127_1221428_2 Biopolymer transport protein K03560 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000001431 149.0
TLS3_k127_1221428_3 Tol-Pal system TolA K03646 - - 0.00000001399 66.0
TLS3_k127_1224467_0 ABC transporter transmembrane region K06147 - - 0.00000000788 59.0
TLS3_k127_1249817_0 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 542.0
TLS3_k127_1249817_1 Dihydrodipicolinate reductase, C-terminus K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000004953 255.0
TLS3_k127_1250287_0 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006895 337.0
TLS3_k127_1250287_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006914 299.0
TLS3_k127_1250287_2 PFAM Dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 285.0
TLS3_k127_1250287_3 Phospholipase D Active site motif K01115 - 3.1.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000172 284.0
TLS3_k127_1250287_4 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000004738 223.0
TLS3_k127_1250287_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000005393 151.0
TLS3_k127_1250287_6 - - - - 0.00000001255 62.0
TLS3_k127_1250621_0 histidine kinase A domain protein - - - 5.418e-212 687.0
TLS3_k127_1250621_1 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 458.0
TLS3_k127_1250621_2 NAD(P)H-dependent FMN reductase K11811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009673 377.0
TLS3_k127_1250621_3 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000001462 175.0
TLS3_k127_1250621_4 Regulatory protein ArsR K03892 - - 0.000000000000000000000000001394 117.0
TLS3_k127_1261148_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 2.259e-206 656.0
TLS3_k127_1261148_1 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 573.0
TLS3_k127_1261148_2 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000006954 210.0
TLS3_k127_1261148_3 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000003485 123.0
TLS3_k127_1261148_4 - - - - 0.000000002622 63.0
TLS3_k127_1261148_5 Tetratricopeptide repeat K08884,K12132 - 2.7.11.1 0.000000003866 66.0
TLS3_k127_1264362_0 ABC transporter - - - 6.773e-247 771.0
TLS3_k127_1264362_1 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 550.0
TLS3_k127_1264362_2 COG1943 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 342.0
TLS3_k127_1264362_3 PFAM amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006712 270.0
TLS3_k127_1270905_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 533.0
TLS3_k127_1270905_1 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 361.0
TLS3_k127_127286_0 Belongs to the glycosyl hydrolase 2 family K05970 - 3.1.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 610.0
TLS3_k127_127286_1 Methyltransferase K00564 - 2.1.1.172 0.0000000000000000000000000000000000000000000000000000000000000000002255 234.0
TLS3_k127_127286_2 TraB family - - - 0.00000000000000000000000000000000000000000000000003471 193.0
TLS3_k127_1274290_0 Peptidase family M13 K07386 - - 1.303e-223 713.0
TLS3_k127_1274290_1 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003454 266.0
TLS3_k127_1274290_2 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001489 251.0
TLS3_k127_1274290_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000001813 204.0
TLS3_k127_1274290_4 membrane - - - 0.0000000000000000000000000000000000000000001214 167.0
TLS3_k127_1274290_5 Protein of unknown function (DUF1232) - - - 0.000000000000000000000002592 110.0
TLS3_k127_1275858_0 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 452.0
TLS3_k127_1275858_1 Glycosyltransferase Family 4 K13668 - 2.4.1.346 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 411.0
TLS3_k127_1275858_2 AAA domain - - - 0.000000000000006748 76.0
TLS3_k127_128472_0 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008329 267.0
TLS3_k127_128472_1 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001259 237.0
TLS3_k127_128472_2 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000006382 216.0
TLS3_k127_12870_0 Elements of external origin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 423.0
TLS3_k127_1292325_0 COG3666 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 331.0
TLS3_k127_1296408_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 574.0
TLS3_k127_1296408_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 525.0
TLS3_k127_1296408_10 Belongs to the UPF0434 family K09791 - - 0.000000000000000000002547 94.0
TLS3_k127_1296408_2 Lipoprotein releasing system transmembrane protein K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 472.0
TLS3_k127_1296408_3 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 289.0
TLS3_k127_1296408_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 292.0
TLS3_k127_1296408_5 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001528 275.0
TLS3_k127_1296408_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000006426 256.0
TLS3_k127_1296408_7 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000002264 239.0
TLS3_k127_1296408_8 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000004675 143.0
TLS3_k127_1296408_9 Biopolymer transport protein K03559 - - 0.000000000000000000000000000000003 133.0
TLS3_k127_1302609_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 334.0
TLS3_k127_1302609_1 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 291.0
TLS3_k127_1302609_2 3' exoribonuclease family, domain 2 K00989 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000001645 220.0
TLS3_k127_1302609_3 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000004621 122.0
TLS3_k127_1311569_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008946 413.0
TLS3_k127_1311569_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 385.0
TLS3_k127_1311569_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000009476 119.0
TLS3_k127_1315745_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000001081 197.0
TLS3_k127_1315745_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000004034 194.0
TLS3_k127_1324463_0 PFAM extracellular solute-binding protein, family 3 K16254 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009951 311.0
TLS3_k127_1324463_1 Phosphate-starvation-inducible E - - - 0.000000000000000000000000000000000000000003183 160.0
TLS3_k127_1326205_0 Pfam Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 5.375e-301 938.0
TLS3_k127_1326205_1 COG1943 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 295.0
TLS3_k127_1326205_2 Pfam Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 0.000000000000000000000000222 107.0
TLS3_k127_1335248_0 Tryptophan halogenase K14266 - 1.14.19.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 479.0
TLS3_k127_1335248_1 Tryptophan halogenase K14266 - 1.14.19.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 360.0
TLS3_k127_1335248_2 Tryptophan halogenase K14266 - 1.14.19.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 332.0
TLS3_k127_1336429_0 Glycosyl transferase family 21 - - - 0.0 1039.0
TLS3_k127_1336429_1 oxidase, subunit K00425 - 1.10.3.14 1.716e-195 619.0
TLS3_k127_1336429_2 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000969 263.0
TLS3_k127_1336429_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000004442 175.0
TLS3_k127_1336429_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000002171 87.0
TLS3_k127_135306_0 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 452.0
TLS3_k127_135306_1 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 349.0
TLS3_k127_135306_2 PFAM Peptidase M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004291 244.0
TLS3_k127_1367296_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 8.837e-206 651.0
TLS3_k127_1367296_1 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 349.0
TLS3_k127_1367296_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001895 284.0
TLS3_k127_1367296_3 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001808 265.0
TLS3_k127_1367296_4 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000001768 147.0
TLS3_k127_13704_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 554.0
TLS3_k127_13704_1 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 504.0
TLS3_k127_13704_2 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 285.0
TLS3_k127_13704_3 BFD-like [2Fe-2S] binding domain - - - 0.0000000000000000000001143 99.0
TLS3_k127_13704_4 PAS domain - - - 0.000000000000000008595 85.0
TLS3_k127_1384196_0 ATPases associated with a variety of cellular activities K05776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006103 287.0
TLS3_k127_1386261_0 synthase - - - 1.934e-230 729.0
TLS3_k127_1386261_1 Putative auto-transporter adhesin, head GIN domain - - - 0.00002687 54.0
TLS3_k127_1390698_0 Belongs to the cysteine synthase cystathionine beta- synthase family - - - 8.642e-218 687.0
TLS3_k127_1390698_1 protein conserved in bacteria - - - 6.204e-210 672.0
TLS3_k127_1390698_2 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K00499,K16319 - 1.14.12.1,1.14.15.7 6.437e-196 616.0
TLS3_k127_1390698_3 Amino acid permease K03294,K03759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 520.0
TLS3_k127_1390698_4 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000003276 216.0
TLS3_k127_1408071_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 463.0
TLS3_k127_1408071_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 338.0
TLS3_k127_1408071_2 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004623 271.0
TLS3_k127_1408071_3 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000008964 230.0
TLS3_k127_1408071_4 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000002643 154.0
TLS3_k127_1408071_5 Protein of unknown function (DUF1289) K06938 - - 0.00000008084 56.0
TLS3_k127_141803_0 bifunctional purine biosynthesis protein PurH K00602 GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 7.072e-213 674.0
TLS3_k127_141803_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 GO:0002943,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 421.0
TLS3_k127_141803_2 Ribosomal protein L11 methyltransferase K02687 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000398 288.0
TLS3_k127_141803_3 Protein of unknown function (DUF3426) - - - 0.0000000000000000000008068 108.0
TLS3_k127_141803_4 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K03557 - - 0.00000000000000000000896 94.0
TLS3_k127_1426479_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 355.0
TLS3_k127_1426479_1 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000003066 192.0
TLS3_k127_1426479_2 Belongs to the skp family K06142 - - 0.00000000000000000000000000000004237 132.0
TLS3_k127_1426479_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000002329 89.0
TLS3_k127_1442211_0 - - - - 0.00000000000000000000000000000000000000000000000000000001191 204.0
TLS3_k127_1442211_1 GGDEF domain - - - 0.000000000000000000000000000001221 135.0
TLS3_k127_1442211_2 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.000000000005078 74.0
TLS3_k127_1465045_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000171 167.0
TLS3_k127_1465045_1 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000001092 133.0
TLS3_k127_1465045_2 Bacterial protein of unknown function (DUF924) - - - 0.0000000000000000000000001565 108.0
TLS3_k127_1465045_3 Bacterial protein of unknown function (DUF924) - - - 0.0000000000000000004713 88.0
TLS3_k127_1473060_0 Amidohydrolase family K06015 - 3.5.1.81 2.544e-222 707.0
TLS3_k127_1473060_1 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 341.0
TLS3_k127_1473060_2 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000483 193.0
TLS3_k127_1473060_3 serine dehydratase beta chain K01752 - 4.3.1.17 0.00000000000000000000000000000000000000000000001032 176.0
TLS3_k127_1473060_4 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000002213 154.0
TLS3_k127_1473060_5 membrane - - - 0.000000000000000000000000000000698 124.0
TLS3_k127_1473060_6 ThiF family K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0019344,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.80,2.8.1.11 0.00009733 46.0
TLS3_k127_1496951_0 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 374.0
TLS3_k127_1496951_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000009176 92.0
TLS3_k127_1499927_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 7.851e-223 695.0
TLS3_k127_1499927_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 376.0
TLS3_k127_1499927_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000009162 220.0
TLS3_k127_1504172_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1197.0
TLS3_k127_1504172_1 photoreceptor activity K11527 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000626 261.0
TLS3_k127_1506148_0 peptidase K01354 - 3.4.21.83 5.38e-249 788.0
TLS3_k127_1506148_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 333.0
TLS3_k127_1506148_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000281 149.0
TLS3_k127_1506148_3 Histidine kinase-like ATPases - - - 0.0000000000000000000000000005569 122.0
TLS3_k127_1506148_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000003873 70.0
TLS3_k127_1506148_5 chaperone-mediated protein folding - - - 0.00003661 57.0
TLS3_k127_1514431_0 Saccharopine dehydrogenase NADP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 394.0
TLS3_k127_1514431_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008462 387.0
TLS3_k127_1514431_2 alpha/beta hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 331.0
TLS3_k127_1514431_3 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000003892 202.0
TLS3_k127_1514431_4 receiver - - - 0.000000000000000000000000000000000000000000000002417 190.0
TLS3_k127_1523391_0 hydrolase K20881 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000242 254.0
TLS3_k127_1523391_1 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000002886 221.0
TLS3_k127_1523391_2 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000003588 154.0
TLS3_k127_1523391_3 small protein containing a coiled-coil domain - - - 0.00000000000009333 74.0
TLS3_k127_1523391_4 Protein of unknown function (DUF3301) - - - 0.0000000000006277 76.0
TLS3_k127_1538064_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1287.0
TLS3_k127_1542934_0 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 5.612e-232 740.0
TLS3_k127_1542934_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 318.0
TLS3_k127_1542934_2 Putative peptidoglycan binding domain K02450 - - 0.000000000000000000000000000001263 136.0
TLS3_k127_1542934_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000003158 114.0
TLS3_k127_1542934_4 (FHA) domain - - - 0.0000000000005673 81.0
TLS3_k127_1545931_0 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 639.0
TLS3_k127_1545931_1 Membrane - - - 0.0000000000000001162 90.0
TLS3_k127_155827_0 Enoyl-CoA hydratase/isomerase K13816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002444 289.0
TLS3_k127_155827_1 Histidine kinase K10715 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000002494 244.0
TLS3_k127_1558875_0 Belongs to the glycosyl hydrolase 13 family - - - 0.0 1018.0
TLS3_k127_1558875_1 High confidence in function and specificity - - - 8.458e-208 668.0
TLS3_k127_1558875_2 Glycosyl transferase family 21 K03669 GO:0005575,GO:0016020 - 3.458e-205 672.0
TLS3_k127_1558875_3 Alpha amylase, catalytic domain K01236 - 3.2.1.141 2.811e-194 626.0
TLS3_k127_1558875_4 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 GO:0000271,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0030288,GO:0030313,GO:0031975,GO:0033692,GO:0034637,GO:0034645,GO:0042597,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0051273,GO:0051274,GO:0071704,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 442.0
TLS3_k127_1558875_5 TIGRFAM Malto-oligosyltrehalose synthase K06044 - 5.4.99.15 0.000000000000000000000000000000000000000000000000000000232 203.0
TLS3_k127_1558875_6 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000001294 179.0
TLS3_k127_1591389_0 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000003636 230.0
TLS3_k127_1591389_1 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000000000000000003127 183.0
TLS3_k127_1598847_0 cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 305.0
TLS3_k127_1598847_1 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007402 265.0
TLS3_k127_1599071_0 Homospermidine synthase K00808 - 2.5.1.44 1.492e-239 749.0
TLS3_k127_1606265_0 basal body rod K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 385.0
TLS3_k127_1606265_1 TIGRFAM flagellar basal-body rod protein FlgF K02391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009674 281.0
TLS3_k127_1606265_2 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000000000000000001456 210.0
TLS3_k127_1606344_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 421.0
TLS3_k127_1606344_1 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 392.0
TLS3_k127_1606344_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000006015 218.0
TLS3_k127_1606344_3 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000004415 182.0
TLS3_k127_1645388_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000861 419.0
TLS3_k127_1645388_1 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001816 241.0
TLS3_k127_1645388_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000002452 235.0
TLS3_k127_1645388_3 - - - - 0.0000000000003078 74.0
TLS3_k127_1672660_0 Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system K01194 - 3.2.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004868 281.0
TLS3_k127_1672660_1 FecR protein K07165 - - 0.000000000000000000000000005546 120.0
TLS3_k127_1672660_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000001058 92.0
TLS3_k127_1692900_0 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 3.6e-210 671.0
TLS3_k127_1692900_1 SMART alpha amylase catalytic sub domain K01236 - 3.2.1.141 0.0000000000000000000004804 100.0
TLS3_k127_1766336_0 Belongs to the TPP enzyme family K00156 - 1.2.5.1 7.281e-279 867.0
TLS3_k127_1766336_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 374.0
TLS3_k127_1766336_2 HWE histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001599 287.0
TLS3_k127_1766336_3 Belongs to the heme-copper respiratory oxidase family K02274,K15408 - 1.9.3.1 0.00000000008938 66.0
TLS3_k127_1766336_4 - - - - 0.0001077 50.0
TLS3_k127_1775666_0 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000001538 187.0
TLS3_k127_1775666_1 TIGRFAM Tyrosine-protein kinase, chain length determinant protein EpsG - - - 0.0000000000000000000000000007632 116.0
TLS3_k127_1775666_2 - - - - 0.000000000000000000000004476 116.0
TLS3_k127_1775827_0 acyl-CoA dehydrogenase K06445 GO:0003674,GO:0003824,GO:0003995,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 - 2.253e-239 756.0
TLS3_k127_1775827_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 310.0
TLS3_k127_1775827_2 NADH pyrophosphatase zinc ribbon domain K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 292.0
TLS3_k127_1775827_3 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000624 250.0
TLS3_k127_1775827_4 Surface antigen variable number K07278 - - 0.00000000000000000000000000000000000000000000001634 186.0
TLS3_k127_1792479_0 Acyltransferase family K11941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001236 274.0
TLS3_k127_1792479_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001116 248.0
TLS3_k127_1792479_2 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000006979 190.0
TLS3_k127_1823441_0 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 391.0
TLS3_k127_1823441_1 tellurite resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002709 234.0
TLS3_k127_1823441_2 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000002106 231.0
TLS3_k127_1823441_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000011 145.0
TLS3_k127_1823441_4 Domain of unknown function (DUF4252) - - - 0.000000000000000000000000000003875 126.0
TLS3_k127_182589_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 4.183e-215 690.0
TLS3_k127_182589_1 - - - - 0.00000778 57.0
TLS3_k127_1849146_0 membrane - - - 1.608e-223 725.0
TLS3_k127_1849146_1 Tryptophan halogenase - - - 1.328e-212 672.0
TLS3_k127_1849146_10 dehydratase - - - 0.000000000000000007118 87.0
TLS3_k127_1849146_2 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 497.0
TLS3_k127_1849146_3 Bacterial lipid A biosynthesis acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 340.0
TLS3_k127_1849146_4 pteridine-dependent deoxygenase K18240 - 4.1.3.40,4.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000000000326 256.0
TLS3_k127_1849146_5 Beta-ketoacyl synthase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000001355 222.0
TLS3_k127_1849146_6 acyl carrier protein K02078 - - 0.00000000000000000000000000000000005334 135.0
TLS3_k127_1849146_7 dehydratase - - - 0.000000000000000000000000000000003009 150.0
TLS3_k127_1849146_8 Fatty acyl CoA synthetase - - - 0.00000000000000000000000000000001785 135.0
TLS3_k127_1849146_9 membrane - - - 0.000000000000000000000000000005284 124.0
TLS3_k127_1859988_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000001253 231.0
TLS3_k127_1859988_1 BAAT / Acyl-CoA thioester hydrolase C terminal K06889 - - 0.0000000000000000000000000000000000000000001392 176.0
TLS3_k127_1870912_0 Epoxide hydrolase N terminus K01253,K21159 - 3.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000004769 244.0
TLS3_k127_1870912_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000001027 215.0
TLS3_k127_1870912_2 Ethanolamine utilisation protein EutQ - - - 0.00000000000000000000000000000000000000000000003727 175.0
TLS3_k127_1870912_3 Cupin domain - - - 0.0000000000000000000000000000000000000006062 153.0
TLS3_k127_1870912_4 Protein of unknown function (DUF2798) - - - 0.0000000000000000000004258 97.0
TLS3_k127_1886564_0 ORF located using Glimmer GeneMark Blastx COG0841 TC K03296,K18138 - - 4.197e-266 839.0
TLS3_k127_1886564_1 RND efflux system, outer membrane K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 323.0
TLS3_k127_1886564_2 Bacterial protein of unknown function (DUF924) - - - 0.0000000000000000000000005479 109.0
TLS3_k127_1886564_3 PilZ domain - - - 0.000007932 53.0
TLS3_k127_1892984_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.0 1588.0
TLS3_k127_1892984_1 Amino acid permease K03294,K16238 - - 2.038e-201 647.0
TLS3_k127_1892984_10 Histidine kinase K14986 - 2.7.13.3 0.00000000000000000000000000000006261 131.0
TLS3_k127_1892984_11 - - - - 0.0000000000000000007701 97.0
TLS3_k127_1892984_12 Protein of unknown function (DUF2845) - - - 0.00000000000002199 79.0
TLS3_k127_1892984_2 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 550.0
TLS3_k127_1892984_3 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006523 535.0
TLS3_k127_1892984_4 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 401.0
TLS3_k127_1892984_5 Multidrug efflux pump K03327 GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 324.0
TLS3_k127_1892984_6 Peptidase S46 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005144 278.0
TLS3_k127_1892984_7 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000002921 232.0
TLS3_k127_1892984_8 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000003788 183.0
TLS3_k127_1892984_9 membrane - - - 0.0000000000000000000000000000000000000001378 154.0
TLS3_k127_1897443_0 WD40-like Beta Propeller Repeat - - - 7.246e-261 821.0
TLS3_k127_1897443_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 428.0
TLS3_k127_1897443_2 FIST N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 349.0
TLS3_k127_1897443_3 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 330.0
TLS3_k127_1897443_4 Dual specificity phosphatase, catalytic domain - - - 0.000000000000000000000000000000000004743 154.0
TLS3_k127_1897443_5 PFAM ADP-ribosylation Crystallin J1 - - - 0.0000000000000000147 96.0
TLS3_k127_1897443_6 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.0000000001515 66.0
TLS3_k127_1900471_0 addiction module antidote protein - - - 0.000000000000000000000000000000000000004209 150.0
TLS3_k127_1900471_1 addiction module killer protein - - - 0.0000000000000000000000000000000000266 136.0
TLS3_k127_1900471_2 - - - - 0.000000000000002244 79.0
TLS3_k127_1900471_3 - - - - 0.000003682 48.0
TLS3_k127_1908064_0 PFAM Transposase IS66 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004482 253.0
TLS3_k127_1908064_1 PFAM IS66 Orf2 like protein K07484 - - 0.0000000000000000000000000004696 117.0
TLS3_k127_1908064_3 PFAM Integrase core domain - - - 0.00008495 50.0
TLS3_k127_1915858_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.077e-201 641.0
TLS3_k127_1915858_1 pfkB family carbohydrate kinase K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006078 448.0
TLS3_k127_1915858_2 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.000000000000000000000000000000000001121 147.0
TLS3_k127_1916903_0 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 394.0
TLS3_k127_1916903_1 UvrD-like helicase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000008317 239.0
TLS3_k127_1916903_2 aminotransferase K14260 - 2.6.1.2,2.6.1.66 0.0000000000000000000000000003712 117.0
TLS3_k127_1925717_0 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 424.0
TLS3_k127_1925717_1 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 347.0
TLS3_k127_1925717_2 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 309.0
TLS3_k127_1925717_3 Role in flagellar biosynthesis K02421 - - 0.00000000000000000000000000000000000000000000000000000000000000004115 231.0
TLS3_k127_1925717_4 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 - - 0.000000000000000000000000000000000000000000009127 164.0
TLS3_k127_1925717_5 Role in flagellar biosynthesis K02420 - - 0.000000000000000000000000000000008676 129.0
TLS3_k127_1925717_6 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000000000000001845 126.0
TLS3_k127_1925717_7 PFAM flagellar biosynthesis protein, FliO K02418 - - 0.0000000000001942 80.0
TLS3_k127_1935315_0 UPF0313 protein - - - 0.0 1067.0
TLS3_k127_1935315_1 Methylpurine-DNA glycosylase (MPG) K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000004987 207.0
TLS3_k127_1962413_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 363.0
TLS3_k127_1962413_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008031 359.0
TLS3_k127_1969462_0 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 470.0
TLS3_k127_1969462_2 Amidohydrolase family - - - 0.0000000000000000000000000000000002701 135.0
TLS3_k127_1969462_3 - - - - 0.0000000000000000000000000000002002 135.0
TLS3_k127_1969462_4 OmpA family - - - 0.000000002865 70.0
TLS3_k127_1969462_5 Belongs to the SlyX family K03745 - - 0.000786 45.0
TLS3_k127_1982762_0 Serine dehydratase K01752 - 4.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008218 534.0
TLS3_k127_1982762_1 receptor K16087 - - 0.000000000000000000000000000000000000000000002812 169.0
TLS3_k127_1982762_2 membrane - - - 0.0000000000005705 70.0
TLS3_k127_1986440_0 Protein phosphatase 2A homologues, catalytic domain. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 314.0
TLS3_k127_1986440_1 Belongs to the UPF0337 (CsbD) family - - - 0.0000000000000000009377 89.0
TLS3_k127_1986440_2 COG1943 Transposase and inactivated derivatives - - - 0.00000008635 58.0
TLS3_k127_1994699_0 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000002543 228.0
TLS3_k127_1994699_1 Zn-dependent protease with chaperone - - - 0.00000000000000000000000000000000000000000000000000000000003529 224.0
TLS3_k127_2016060_0 DNA ligase K01971 - 6.5.1.1 0.0 1081.0
TLS3_k127_2016060_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 364.0
TLS3_k127_2016060_2 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 320.0
TLS3_k127_2016060_3 Acyl-CoA oxidase K00232 - 1.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 325.0
TLS3_k127_2016060_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 296.0
TLS3_k127_2016060_5 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001457 278.0
TLS3_k127_2016060_6 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000002704 233.0
TLS3_k127_2025841_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 9.829e-208 658.0
TLS3_k127_2025841_1 Glutathione S-transferase, C-terminal domain K07393 - 1.8.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 482.0
TLS3_k127_2025841_2 TonB-dependent Receptor Plug Domain K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009951 396.0
TLS3_k127_2025841_3 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 312.0
TLS3_k127_2025841_4 Domain of unknown function (DUF4154) - - - 0.000000000000000001601 93.0
TLS3_k127_2025841_5 Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000008743 84.0
TLS3_k127_2034125_0 E-Z type HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 361.0
TLS3_k127_2034125_1 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000466 231.0
TLS3_k127_2059498_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000004496 269.0
TLS3_k127_2059498_1 protein conserved in bacteria K09974 - - 0.00000000000000000000000000000000000000000000000000000000000000002327 238.0
TLS3_k127_2059498_2 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000007673 205.0
TLS3_k127_2059498_3 Putative esterase K07214 - - 0.000000000000000000000000000000000000000000000000000002276 199.0
TLS3_k127_2059498_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000005483 181.0
TLS3_k127_2059498_5 Shikimate kinase K00851 - 2.7.1.12 0.0000000000000000000000000000000000007685 146.0
TLS3_k127_2059498_6 Acetyltransferase (GNAT) domain K03830 - - 0.00000000000000000000000000000000001669 147.0
TLS3_k127_2068603_0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 320.0
TLS3_k127_2068603_1 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000000000000000004204 201.0
TLS3_k127_2068603_2 Peptidase S24-like K03100 - 3.4.21.89 0.00000000000000000000000000000002902 127.0
TLS3_k127_2068603_3 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000036 96.0
TLS3_k127_2075771_0 Belongs to the radical SAM superfamily. PqqE family K06139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 576.0
TLS3_k127_2075771_1 Protein of unknown function (DUF4256) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009822 289.0
TLS3_k127_2075771_2 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003402 254.0
TLS3_k127_2075771_3 COG0662 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004639 252.0
TLS3_k127_2075771_4 Pfam:Pyridox_oxidase K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000007306 198.0
TLS3_k127_2075771_5 Cupin domain - - - 0.000000000000000000000000000000000000000000000000002791 184.0
TLS3_k127_2075771_6 Transcriptional regulator K07978 - - 0.000000000000000000000000000000000000000001545 162.0
TLS3_k127_2075771_8 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.0000009973 51.0
TLS3_k127_2087397_0 Subunit A of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K05559 - - 0.0 1260.0
TLS3_k127_2087397_1 alpha amylase catalytic K05343 - 3.2.1.1,5.4.99.16 0.0 1084.0
TLS3_k127_2087397_10 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0002475 53.0
TLS3_k127_2087397_2 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K05561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 600.0
TLS3_k127_2087397_3 Homospermidine synthase K00808 - 2.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 489.0
TLS3_k127_2087397_4 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K05560 - - 0.000000000000000000000000000000000000000000000000115 182.0
TLS3_k127_2087397_5 Na+/H+ ion antiporter subunit K05562 - - 0.0000000000000000000000000000000000000002316 161.0
TLS3_k127_2087397_6 Prokaryotic N-terminal methylation motif K02655 - - 0.000000000000000000000000000000000000002362 152.0
TLS3_k127_2087397_7 Monovalent cation proton antiporter subunit MnhG PhaG K05564 - - 0.000000000000000000000000000000000001571 141.0
TLS3_k127_2087397_8 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K05563 - - 0.000000000000000000000000000002678 122.0
TLS3_k127_2087397_9 Histidine kinase K07636 - 2.7.13.3 0.0000005395 62.0
TLS3_k127_2096094_0 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 413.0
TLS3_k127_2096094_1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 293.0
TLS3_k127_2096094_2 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 284.0
TLS3_k127_2096094_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K04756 - - 0.00000000000000000000000000000000000000000000000000000007858 202.0
TLS3_k127_2096094_4 CHAT domain - - - 0.00000000000000000000000000000000000000000000000004666 195.0
TLS3_k127_2096094_5 Belongs to the Nudix hydrolase family K01518 - 3.6.1.17 0.0000000000000000000000000000000000000000001391 162.0
TLS3_k127_2096094_6 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000001007 106.0
TLS3_k127_2096460_0 Integral membrane sensor signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 313.0
TLS3_k127_2096460_1 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009085 273.0
TLS3_k127_2096460_2 - - - - 0.0000000000000001225 85.0
TLS3_k127_2096460_3 THIoesterase K18700 - 3.1.2.29 0.0000000000001162 72.0
TLS3_k127_2113303_0 Type VI secretion K07169,K11894,K11913 - - 0.000000000000000000000000000000000000000000000000000000001157 218.0
TLS3_k127_2113303_1 Domain of unknown function (DUF1820) - - - 0.0000000000000000000000000000000000002162 144.0
TLS3_k127_2140148_0 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002939 272.0
TLS3_k127_2140148_1 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000005936 238.0
TLS3_k127_2140148_2 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000003441 205.0
TLS3_k127_2140148_3 COG2867 Oligoketide cyclase lipid transport protein - GO:0003674,GO:0005488,GO:0006417,GO:0006446,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044877,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000001319 143.0
TLS3_k127_2140148_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0030674,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042221,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045203,GO:0045229,GO:0046677,GO:0050896,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0060090,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.000000000000004194 79.0
TLS3_k127_2140148_5 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000000842 79.0
TLS3_k127_2140148_6 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000017 50.0
TLS3_k127_2153297_0 membrane protein involved in D-alanine K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 510.0
TLS3_k127_2153297_1 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 471.0
TLS3_k127_2153297_10 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000347 131.0
TLS3_k127_2153297_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 318.0
TLS3_k127_2153297_3 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002654 293.0
TLS3_k127_2153297_4 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000003419 235.0
TLS3_k127_2153297_5 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000005769 230.0
TLS3_k127_2153297_6 lipolytic protein G-D-S-L family K00983 - 2.7.7.43 0.0000000000000000000000000000000000000000000000000104 188.0
TLS3_k127_2153297_7 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000314 166.0
TLS3_k127_2153297_8 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000004117 147.0
TLS3_k127_2153297_9 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000000001305 142.0
TLS3_k127_2159462_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008776,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016741,GO:0016742,GO:0016772,GO:0016774,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 577.0
TLS3_k127_2159462_1 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 301.0
TLS3_k127_2159462_2 Protein of unknown function (DUF2959) - - - 0.000000000000000000000000000000000000000000000000000000000000002837 226.0
TLS3_k127_2159462_3 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000003287 178.0
TLS3_k127_2159462_4 Hemerythrin HHE cation binding domain - - - 0.00000000000000000003198 100.0
TLS3_k127_2168001_0 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 492.0
TLS3_k127_2170711_0 Patatin-like phospholipase - - - 1.484e-202 650.0
TLS3_k127_2188679_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 628.0
TLS3_k127_2188679_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05539 - - 0.0000000000000000000000000004659 116.0
TLS3_k127_2191229_0 Protein of unknown function (DUF1587) - - - 3.189e-235 754.0
TLS3_k127_2191229_1 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 523.0
TLS3_k127_2191229_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 424.0
TLS3_k127_2191229_3 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000004321 226.0
TLS3_k127_2191229_4 Cytochrome C' - - - 0.0000000000000000000002062 103.0
TLS3_k127_2193878_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 2.591e-237 753.0
TLS3_k127_2200399_0 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001449 254.0
TLS3_k127_2200399_1 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000802 250.0
TLS3_k127_2200399_2 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000001497 191.0
TLS3_k127_2200399_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000001125 187.0
TLS3_k127_2200399_4 Cupin 2, conserved barrel domain protein K21700 - - 0.000000000000000000000000000000002876 134.0
TLS3_k127_2200399_5 Histidine kinase - - - 0.0000000004408 72.0
TLS3_k127_2211534_0 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000001617 180.0
TLS3_k127_2211534_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000007985 127.0
TLS3_k127_2211534_2 permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000002069 119.0
TLS3_k127_2211534_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000004809 71.0
TLS3_k127_2211534_4 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000005742 69.0
TLS3_k127_2217873_0 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 496.0
TLS3_k127_2217873_1 E3 component of 2-oxoglutarate dehydrogenase complex K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000001484 183.0
TLS3_k127_2222388_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00124 - - 9.515e-246 768.0
TLS3_k127_2222388_1 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 1.014e-214 669.0
TLS3_k127_2222388_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K22015 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0015942,GO:0015944,GO:0016491,GO:0016651,GO:0016999,GO:0017144,GO:0019752,GO:0030151,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704 1.17.1.9,1.17.99.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 550.0
TLS3_k127_2222388_3 SMART Extracellular solute-binding protein, family 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 327.0
TLS3_k127_2222388_4 Glutathione-dependent formaldehyde-activating enzyme K03396 - 4.4.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 301.0
TLS3_k127_2222388_5 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00127,K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000227 192.0
TLS3_k127_2222388_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000001294 167.0
TLS3_k127_2224598_0 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 324.0
TLS3_k127_2224598_1 Domain related to MnhB subunit of Na+/H+ antiporter - - - 0.000000000000000000000000000000000000000000000000000000000000000007765 239.0
TLS3_k127_2224598_2 PFAM cation antiporter K05569 - - 0.0000000000000000000000000000007886 128.0
TLS3_k127_2224598_3 PFAM Na H antiporter subunit K05571 - - 0.0000000000000000000000000211 112.0
TLS3_k127_2224598_4 antiporter activity K05570 - - 0.0000000000000000000000004908 107.0
TLS3_k127_2229369_0 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 395.0
TLS3_k127_2229369_1 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000001593 201.0
TLS3_k127_2235936_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 332.0
TLS3_k127_2235936_1 Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001194 252.0
TLS3_k127_2235936_2 Protein of unknown function (DUF3096) - - - 0.000000000006664 68.0
TLS3_k127_2235936_3 - - - - 0.00000000002055 71.0
TLS3_k127_2236393_0 COG1404 Subtilisin-like serine proteases K14645 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 557.0
TLS3_k127_2236393_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000002412 276.0
TLS3_k127_2237140_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 525.0
TLS3_k127_2237140_1 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001247 271.0
TLS3_k127_2237140_2 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000001591 126.0
TLS3_k127_2249016_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 411.0
TLS3_k127_2249016_1 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 327.0
TLS3_k127_2249016_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003406 271.0
TLS3_k127_2257894_0 PFAM Carbon starvation protein CstA K06200 - - 0.0 1035.0
TLS3_k127_2257894_1 Belongs to the UPF0276 family K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 365.0
TLS3_k127_2257894_11 Sigma-54 interaction domain - - - 0.000000002886 62.0
TLS3_k127_2257894_12 Selenoprotein, putative - - - 0.0000003423 61.0
TLS3_k127_2257894_2 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 327.0
TLS3_k127_2257894_3 fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 305.0
TLS3_k127_2257894_4 CHASE3 domain K05962 - 2.7.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003167 283.0
TLS3_k127_2257894_5 Maleylacetoacetate isomerase K01801 - 5.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000005981 246.0
TLS3_k127_2257894_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.0000000000000000000000000000000000000000000000000000000000361 221.0
TLS3_k127_2257894_7 Putative DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000007189 184.0
TLS3_k127_2257894_8 SMART Transport-associated and nodulation region K04065 - - 0.000000000000000001698 89.0
TLS3_k127_2257894_9 - - - - 0.000000000000000006264 91.0
TLS3_k127_2260948_0 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 307.0
TLS3_k127_2260948_1 Protein of unknown function (DUF3500) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001075 291.0
TLS3_k127_2260948_2 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000001142 186.0
TLS3_k127_2260948_3 Protein of unknown function (DUF3224) - - - 0.00000000000000000000000000000000000002879 153.0
TLS3_k127_2262416_0 lactate metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008204 402.0
TLS3_k127_2262416_1 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000002229 169.0
TLS3_k127_2262416_2 Protein of unknown function DUF86 - - - 0.000000006902 59.0
TLS3_k127_2262416_3 Protein of unknown function DUF86 - - - 0.0001344 46.0
TLS3_k127_2272547_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 3.385e-239 747.0
TLS3_k127_2272547_1 NADP transhydrogenase K00324 - 1.6.1.2 1.395e-196 618.0
TLS3_k127_2272547_2 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000007186 176.0
TLS3_k127_2272547_3 membrane - - - 0.000003071 58.0
TLS3_k127_2290065_0 FAD linked oxidase domain protein - - - 0.0 1888.0
TLS3_k127_2290065_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 482.0
TLS3_k127_2290065_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 311.0
TLS3_k127_2290065_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 312.0
TLS3_k127_2290065_4 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001288 256.0
TLS3_k127_2290065_5 FAD linked oxidase domain protein - - - 0.000000000000000000000000002701 114.0
TLS3_k127_2295693_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007633 279.0
TLS3_k127_2295693_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000003786 166.0
TLS3_k127_2295693_2 Tyrosine phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000000000000000001679 157.0
TLS3_k127_2295693_3 - - - - 0.0000000000000000003199 90.0
TLS3_k127_2295693_4 Periplasmic protein TonB links inner and outer membranes K03832 - - 0.000000009089 63.0
TLS3_k127_2297108_0 Belongs to the citrate synthase family K01647 GO:0003674,GO:0003824,GO:0004108,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0036440,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046912,GO:0055114,GO:0071704,GO:0072350 2.3.3.1 6.152e-197 623.0
TLS3_k127_2297108_1 mRNA catabolic process - - - 0.0000000001049 64.0
TLS3_k127_2297108_2 Peptidase family M48 - - - 0.0001475 44.0
TLS3_k127_2300051_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 4.079e-211 663.0
TLS3_k127_2300051_1 PFAM Pyruvate carboxyltransferase K01640,K18314 - 4.1.3.4,4.1.3.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 360.0
TLS3_k127_2300051_2 Peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000007623 226.0
TLS3_k127_2300051_3 FCD - - - 0.000000000000000000000000000000000000000000000000008213 189.0
TLS3_k127_2309003_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 360.0
TLS3_k127_2309003_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009477 301.0
TLS3_k127_2309003_2 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000008423 235.0
TLS3_k127_2309003_3 diguanylate cyclase - - - 0.0000000000000000000000000004463 126.0
TLS3_k127_2311076_0 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 537.0
TLS3_k127_2311076_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000003286 202.0
TLS3_k127_2314675_0 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 302.0
TLS3_k127_2314675_1 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000001287 243.0
TLS3_k127_2314675_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000001554 215.0
TLS3_k127_2331937_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 359.0
TLS3_k127_2344436_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008725 382.0
TLS3_k127_2344436_1 Sigma factor regulator FecR K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 362.0
TLS3_k127_2344436_2 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000757 181.0
TLS3_k127_2346443_0 Crp-like helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 314.0
TLS3_k127_2346443_1 BA14K-like protein - - - 0.000000000000000000000000000001638 126.0
TLS3_k127_2364627_0 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 404.0
TLS3_k127_2364627_1 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 354.0
TLS3_k127_2364627_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 321.0
TLS3_k127_2364627_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000001366 65.0
TLS3_k127_2378957_0 DNA-templated transcription, initiation K02405 - - 0.00000000000000000000000000000000000000000000000001518 185.0
TLS3_k127_2378957_1 - - - - 0.00000000000000000919 92.0
TLS3_k127_2379764_0 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 422.0
TLS3_k127_2379764_1 pfkB family carbohydrate kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 382.0
TLS3_k127_2379764_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.0000000000000000000000000000000000000000000000000000000001115 207.0
TLS3_k127_2379764_3 RNA cap guanine-N2 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000003631 194.0
TLS3_k127_2379764_4 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000001129 191.0
TLS3_k127_2379764_5 - - - - 0.0000000000000000000000000000000000000000000000003157 188.0
TLS3_k127_2379764_6 GDP-mannose 4,6 dehydratase K22252 - 1.1.1.135 0.0000000000001811 72.0
TLS3_k127_2379764_7 polysaccharide biosynthetic process - - - 0.00002866 57.0
TLS3_k127_2395609_0 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 336.0
TLS3_k127_2395609_1 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000000000000000005425 216.0
TLS3_k127_2395609_2 Signal peptidase (SPase) II K03101 - 3.4.23.36 0.0000000000000000000000000000000007151 136.0
TLS3_k127_2395609_3 nUDIX hydrolase K01515,K03574,K03801,K08310 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008828,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017144,GO:0018130,GO:0019177,GO:0019438,GO:0019752,GO:0034641,GO:0042364,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0046872,GO:0047429,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.181,3.6.1.13,3.6.1.55,3.6.1.67 0.000000000000000000000000000000002594 136.0
TLS3_k127_2395609_4 - - - - 0.00000000000000000000000007575 110.0
TLS3_k127_2395609_5 - - - - 0.000000000000000000004524 96.0
TLS3_k127_2395609_6 Domain of unknown function (DUF4160) - - - 0.000000000000000000006799 94.0
TLS3_k127_2395609_7 Protein of unknown function (DUF2442) - - - 0.00000000000000006098 83.0
TLS3_k127_2395609_8 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.000000000000005198 74.0
TLS3_k127_2403207_0 TIGRFAM ribonuclease, Rne Rng family K08301 - - 1.508e-198 638.0
TLS3_k127_2403207_1 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000001189 214.0
TLS3_k127_2403207_2 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000002823 193.0
TLS3_k127_2403207_4 Protein of unknown function - - - 0.000000001244 70.0
TLS3_k127_2406442_0 Isocitrate dehydrogenase - - - 2.675e-223 699.0
TLS3_k127_2406442_1 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000559 272.0
TLS3_k127_2406442_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002992 252.0
TLS3_k127_2406442_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000006042 115.0
TLS3_k127_2406442_4 Protein of unknown function (DUF2905) - - - 0.000000000000000000000008633 101.0
TLS3_k127_2412577_0 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000199 205.0
TLS3_k127_2412577_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000005489 204.0
TLS3_k127_2412577_2 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000008456 151.0
TLS3_k127_243103_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000003906 189.0
TLS3_k127_243103_1 Histidine kinase - - - 0.0000000000000000000005198 100.0
TLS3_k127_243103_2 response regulator - - - 0.00000000000000000000211 100.0
TLS3_k127_243103_3 PFAM Flp Fap pilin component K02651 - - 0.0000000001461 64.0
TLS3_k127_2462529_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 4.527e-197 630.0
TLS3_k127_2462529_1 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001925 256.0
TLS3_k127_2462529_2 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000002073 231.0
TLS3_k127_2462529_3 Putative diguanylate phosphodiesterase K21023 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000009769 220.0
TLS3_k127_2462529_4 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000001247 160.0
TLS3_k127_2462529_5 Sterol-binding domain protein K03690 - - 0.0000000000000000000000000000000009607 139.0
TLS3_k127_2478_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 432.0
TLS3_k127_2478_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008411 291.0
TLS3_k127_2478_2 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 301.0
TLS3_k127_2482361_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 555.0
TLS3_k127_2482361_1 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 434.0
TLS3_k127_2495009_0 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001417 282.0
TLS3_k127_2495009_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000008466 255.0
TLS3_k127_2495009_2 Belongs to the ATCase OTCase family K09065,K13043 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.11,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000005423 252.0
TLS3_k127_2495328_0 Protein of unknown function (DUF4038) - - - 5.04e-322 994.0
TLS3_k127_2495328_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004331 261.0
TLS3_k127_254048_0 Periplasmic binding protein K01999 - - 8.334e-229 714.0
TLS3_k127_254048_1 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 452.0
TLS3_k127_254048_2 PFAM 6-phosphogluconate dehydrogenase NAD-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 312.0
TLS3_k127_254048_3 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000005853 217.0
TLS3_k127_2543981_0 Pyruvate formate lyase-activating protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 557.0
TLS3_k127_2543981_1 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000002922 269.0
TLS3_k127_2543981_2 OmpA-like transmembrane domain - - - 0.000000000000000000368 95.0
TLS3_k127_2553309_0 peptidase S9 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000334 293.0
TLS3_k127_2553309_1 Putative porin - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000003072 188.0
TLS3_k127_2553309_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000002687 137.0
TLS3_k127_2577267_0 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000000000000000000000000006411 137.0
TLS3_k127_2577267_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000002858 78.0
TLS3_k127_2577267_2 enzyme of heme biosynthesis K02496 - 2.1.1.107 0.0000001584 60.0
TLS3_k127_2582478_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 299.0
TLS3_k127_2582478_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001214 287.0
TLS3_k127_2588834_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 4.356e-279 875.0
TLS3_k127_2588834_1 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 1.389e-242 770.0
TLS3_k127_2588834_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000001477 176.0
TLS3_k127_2588834_11 Protein of unknown function (DUF541) K09807 GO:0000302,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0033554,GO:0034599,GO:0034605,GO:0034614,GO:0042221,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071575,GO:0071944,GO:0098552,GO:1901700,GO:1901701 - 0.0000000000000008313 87.0
TLS3_k127_2588834_12 Membrane protein implicated in regulation of membrane protease activity K07340 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000001806 72.0
TLS3_k127_2588834_13 Putative zinc-finger - - - 0.00000000007294 74.0
TLS3_k127_2588834_14 PFAM conserved - - - 0.00000002447 64.0
TLS3_k127_2588834_15 - - - - 0.0008858 51.0
TLS3_k127_2588834_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 420.0
TLS3_k127_2588834_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 370.0
TLS3_k127_2588834_4 serine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 326.0
TLS3_k127_2588834_5 PFAM YicC-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002861 273.0
TLS3_k127_2588834_6 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000001218 250.0
TLS3_k127_2588834_7 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000008392 231.0
TLS3_k127_2588834_8 Glutathione peroxidase K00432 GO:0003674,GO:0003824,GO:0004601,GO:0004602,GO:0005575,GO:0005623,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0042597,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 1.11.1.9 0.000000000000000000000000000000000000000000000000000000001994 203.0
TLS3_k127_2588834_9 COG0631 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000001169 193.0
TLS3_k127_2590163_0 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000505 203.0
TLS3_k127_2590163_1 PFAM Glycoside hydrolase, family 20, catalytic core K12373 - 3.2.1.52 0.0000002698 61.0
TLS3_k127_26061_0 Methyl-transferase K06983 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 374.0
TLS3_k127_26061_1 Trehalose utilisation K09992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 362.0
TLS3_k127_26061_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 338.0
TLS3_k127_26061_3 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 325.0
TLS3_k127_26061_4 PFAM NnrU protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001751 240.0
TLS3_k127_26061_5 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000000000000000000000000000000000000000001827 165.0
TLS3_k127_2615592_0 Belongs to the IlvD Edd family K01690 - 4.2.1.12 1.786e-268 838.0
TLS3_k127_2615592_1 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247,K13529 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000003243 259.0
TLS3_k127_2615592_2 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000003364 177.0
TLS3_k127_2615592_3 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000009204 147.0
TLS3_k127_2615814_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1226.0
TLS3_k127_2617290_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 9.133e-252 779.0
TLS3_k127_2617290_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.885e-213 672.0
TLS3_k127_2617290_2 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 584.0
TLS3_k127_2617290_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007196 313.0
TLS3_k127_2617290_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 309.0
TLS3_k127_2617290_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000009697 260.0
TLS3_k127_2617290_6 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000003027 239.0
TLS3_k127_2617290_7 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000009137 196.0
TLS3_k127_2617290_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000000000000000000000000003724 183.0
TLS3_k127_2617290_9 preprotein translocase K03075 - - 0.000000000000000000000007007 105.0
TLS3_k127_2624785_0 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 478.0
TLS3_k127_2624785_1 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004213 274.0
TLS3_k127_2624785_2 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000000001372 110.0
TLS3_k127_2624785_3 transport system small permease component - - - 0.000000000000000000000004801 110.0
TLS3_k127_2624785_4 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000134 96.0
TLS3_k127_2624785_5 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000005198 73.0
TLS3_k127_2627085_0 Metal-dependent phosphohydrolase, HD region - - - 0.00000000000000000000000000000007208 143.0
TLS3_k127_2627085_1 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.00000000000000000000000000006261 129.0
TLS3_k127_2627085_2 PFAM metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.000000000000000000000000001372 130.0
TLS3_k127_2646164_0 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000000000000001081 173.0
TLS3_k127_2646164_1 - - - - 0.00000000000000000000000000000000001372 138.0
TLS3_k127_2646164_2 Selenoprotein, putative - - - 0.00000001569 56.0
TLS3_k127_2646671_0 FAD dependent oxidoreductase K09471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004104 271.0
TLS3_k127_2646671_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000002577 150.0
TLS3_k127_2646671_2 Response regulator receiver domain - - - 0.0000000000000000000000000000005247 128.0
TLS3_k127_2646671_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000355 46.0
TLS3_k127_2654683_0 SMART PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 558.0
TLS3_k127_2654683_1 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase K05921 - 4.1.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 390.0
TLS3_k127_2656668_0 Cysteine-rich domain - - - 2.321e-209 659.0
TLS3_k127_2656668_1 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008032 264.0
TLS3_k127_2656668_2 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000004455 115.0
TLS3_k127_2656668_3 COG1960 Acyl-CoA dehydrogenases K20035 - - 0.0000000001279 63.0
TLS3_k127_2665440_0 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 375.0
TLS3_k127_2665440_1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 346.0
TLS3_k127_2665440_2 Glycosyl Transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 293.0
TLS3_k127_2665440_3 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000152 177.0
TLS3_k127_2665440_4 pteridine-dependent deoxygenase K18240 - 4.1.3.40,4.1.3.45 0.00000000000000000000000000000692 122.0
TLS3_k127_2665440_5 oxidoreductase - - - 0.00000000000000000000000000002793 119.0
TLS3_k127_2665440_6 - - - - 0.0000003863 57.0
TLS3_k127_2665440_7 Protein of unknown function (DUF3106) - - - 0.0007788 49.0
TLS3_k127_266778_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 331.0
TLS3_k127_266778_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000001078 161.0
TLS3_k127_2673679_0 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 342.0
TLS3_k127_2674214_0 Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain K00101 - 1.1.2.3 0.000000000000000000000000000000000000000000004629 165.0
TLS3_k127_2674214_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000004441 166.0
TLS3_k127_2674214_2 - - - - 0.00000000000000000000000000000000003518 149.0
TLS3_k127_2674640_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 407.0
TLS3_k127_2674640_1 Exodeoxyribonuclease IX - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 308.0
TLS3_k127_2674640_2 Fructosamine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 294.0
TLS3_k127_2674640_3 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000006828 215.0
TLS3_k127_2674640_4 YCII-related domain K09780 - - 0.00000000000000000000000000000005172 131.0
TLS3_k127_2674640_5 - - - - 0.0002089 49.0
TLS3_k127_2721660_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 605.0
TLS3_k127_2721660_1 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 422.0
TLS3_k127_2721660_2 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 293.0
TLS3_k127_2721660_3 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000001522 237.0
TLS3_k127_2721660_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000003043 218.0
TLS3_k127_2721660_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000000005223 105.0
TLS3_k127_2721660_6 Smr protein MutS2 - - - 0.000000000000000006742 84.0
TLS3_k127_2742605_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1146.0
TLS3_k127_2742605_1 hydroxypyruvate reductase K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 510.0
TLS3_k127_2742605_2 peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 341.0
TLS3_k127_2742605_3 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000002069 66.0
TLS3_k127_2743081_0 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 364.0
TLS3_k127_2743081_1 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003375 246.0
TLS3_k127_2743081_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000115 194.0
TLS3_k127_2765933_0 Alpha-L-arabinofuranosidase K01209 - 3.2.1.55 1.981e-214 675.0
TLS3_k127_2765933_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000006563 175.0
TLS3_k127_2785963_0 glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1448.0
TLS3_k127_2785963_1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000005114 90.0
TLS3_k127_2837495_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.526e-305 945.0
TLS3_k127_2837495_1 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 471.0
TLS3_k127_2837495_2 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 387.0
TLS3_k127_2837495_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000001663 184.0
TLS3_k127_2837495_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000557 156.0
TLS3_k127_2837495_5 adenylate kinase activity K00939 - 2.7.4.3 0.0000000000000000000000000000000000006803 145.0
TLS3_k127_2837495_6 Lipopolysaccharide assembly protein A domain K08992 - - 0.000000003148 62.0
TLS3_k127_2841168_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 5.361e-249 774.0
TLS3_k127_2841168_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.301e-246 769.0
TLS3_k127_2841168_10 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000005366 151.0
TLS3_k127_2841168_11 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000001116 119.0
TLS3_k127_2841168_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009226,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0018130,GO:0019134,GO:0019438,GO:0030203,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0042546,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046872,GO:0055086,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 527.0
TLS3_k127_2841168_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 473.0
TLS3_k127_2841168_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 396.0
TLS3_k127_2841168_5 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 323.0
TLS3_k127_2841168_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006338 304.0
TLS3_k127_2841168_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000000002133 186.0
TLS3_k127_2841168_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000004313 175.0
TLS3_k127_2844264_0 Belongs to the ClpA ClpB family K03694 - - 5.833e-267 828.0
TLS3_k127_2844264_1 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000000009611 169.0
TLS3_k127_2846711_0 Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007141 444.0
TLS3_k127_2846711_1 COG0410 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 357.0
TLS3_k127_2846711_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000003333 102.0
TLS3_k127_2850748_0 HEAT repeats - - - 0.000000000000000009316 95.0
TLS3_k127_2852522_0 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000001349 192.0
TLS3_k127_2852522_1 Belongs to the peptidase S41A family - - - 0.000000000000000000000000000000000000000000414 176.0
TLS3_k127_2852522_2 - - - - 0.0000000000000000000000003974 122.0
TLS3_k127_2854349_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 1.082e-207 655.0
TLS3_k127_2854349_1 two-component system sensor protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008287 310.0
TLS3_k127_2855919_0 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 563.0
TLS3_k127_2855919_1 twitching motility protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 553.0
TLS3_k127_2855919_10 cheY-homologous receiver domain K02658 - - 0.0000000000000000000000000000000000000000009229 159.0
TLS3_k127_2855919_11 Periplasmic protein TonB links inner and outer membranes K03832 - - 0.0000000000000000000000000001357 126.0
TLS3_k127_2855919_12 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000003079 121.0
TLS3_k127_2855919_2 PFAM Type II secretion system protein E K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 417.0
TLS3_k127_2855919_3 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 397.0
TLS3_k127_2855919_4 Oxidoreductase FAD-binding domain K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 382.0
TLS3_k127_2855919_5 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 324.0
TLS3_k127_2855919_6 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000002095 265.0
TLS3_k127_2855919_7 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000001233 242.0
TLS3_k127_2855919_8 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000006969 222.0
TLS3_k127_2855919_9 response regulator K02657 - - 0.0000000000000000000000000000000000000000000000000000000000002486 213.0
TLS3_k127_2885811_0 TIGRFAM RHS repeat-associated core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 458.0
TLS3_k127_289108_0 PQQ enzyme repeat K00117 - 1.1.5.2 5.591e-284 887.0
TLS3_k127_289108_1 COG0471 Di- and tricarboxylate transporters - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 496.0
TLS3_k127_289108_10 - - - - 0.000000000000000000000000000000000000000000004011 173.0
TLS3_k127_289108_11 Protein of unknown function (DUF3037) - - - 0.0000000000000000000000000000000000000000002818 160.0
TLS3_k127_289108_12 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool K06019 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.1 0.00000000000000000006313 98.0
TLS3_k127_289108_13 Extracellular repeat protein, HAF family - - - 0.000002481 59.0
TLS3_k127_289108_2 His Kinase A (phospho-acceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 427.0
TLS3_k127_289108_3 Transfers the fatty acyl group on membrane lipoproteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 370.0
TLS3_k127_289108_4 Serine threonine protein kinase involved in cell cycle control - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 354.0
TLS3_k127_289108_5 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000002315 209.0
TLS3_k127_289108_6 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000107 207.0
TLS3_k127_289108_7 Outer membrane protein W K07275 - - 0.000000000000000000000000000000000000000000000000000000005111 206.0
TLS3_k127_289108_8 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000001534 184.0
TLS3_k127_289108_9 Histidine kinase - - - 0.000000000000000000000000000000000000000000000003714 196.0
TLS3_k127_2899643_0 belongs to the aldehyde dehydrogenase family K00128 GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704 1.2.1.3 4.099e-211 675.0
TLS3_k127_2899643_1 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 609.0
TLS3_k127_2899643_2 Saccharopine dehydrogenase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 450.0
TLS3_k127_2899643_3 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 369.0
TLS3_k127_2899643_4 Oligonucleotide/oligosaccharide-binding (OB)-fold K03578 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 0.0000000000000000000002056 104.0
TLS3_k127_290131_0 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 626.0
TLS3_k127_290131_1 oligopeptide transport K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 597.0
TLS3_k127_290131_2 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 608.0
TLS3_k127_290131_3 Belongs to the ArsC family K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.0000000000000000000000000000000000000000001092 161.0
TLS3_k127_290131_4 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000005841 155.0
TLS3_k127_290131_5 dTDP-4-dehydrorhamnose 3,5-epimerase activity K19068 - 1.1.1.367 0.000000000000000000000000000000008063 132.0
TLS3_k127_290131_6 Protein of unknown function, DUF255 - - - 0.000000000000000000000002894 109.0
TLS3_k127_2907847_0 Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host K05801 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0051087,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003356 280.0
TLS3_k127_2907847_1 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000003585 206.0
TLS3_k127_2907847_2 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000001949 201.0
TLS3_k127_2961565_0 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 418.0
TLS3_k127_2961565_1 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 357.0
TLS3_k127_2961565_2 PFAM coenzyme PQQ synthesis D K06138 - - 0.00000000000000000000000000001097 121.0
TLS3_k127_2987286_0 Peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 387.0
TLS3_k127_2987286_1 Pfam:Pyridox_oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 354.0
TLS3_k127_2987286_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000001885 201.0
TLS3_k127_2987286_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000003312 198.0
TLS3_k127_2987286_4 COG0668 Small-conductance mechanosensitive channel - - - 0.00000000000000000000000000000000000000000000002821 181.0
TLS3_k127_2987286_5 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000003255 147.0
TLS3_k127_2987286_6 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000001381 132.0
TLS3_k127_2987286_7 MgtE intracellular N domain - - - 0.0000000000000000000000008463 115.0
TLS3_k127_2987286_8 MORN repeat variant - - - 0.00000000000002354 79.0
TLS3_k127_2987286_9 antibiotic catabolic process K18235 - - 0.0003341 44.0
TLS3_k127_29917_0 PFAM regulatory protein LacI K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 551.0
TLS3_k127_29917_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 377.0
TLS3_k127_29917_2 - - - - 0.000000000000000000000000000000000000000000000000000000000001347 213.0
TLS3_k127_29917_3 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 0.000006361 48.0
TLS3_k127_2999647_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 479.0
TLS3_k127_2999647_1 RES - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005449 280.0
TLS3_k127_2999647_2 Protein of unknown function (DUF2384) - - - 0.0000000000000000000000000000000000000000000002754 170.0
TLS3_k127_3007156_0 Part of a membrane complex involved in electron transport K03615 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 424.0
TLS3_k127_3007156_1 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000001781 157.0
TLS3_k127_3007156_2 Part of a membrane complex involved in electron transport K03616 - - 0.0006693 43.0
TLS3_k127_3014813_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 344.0
TLS3_k127_3014813_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 340.0
TLS3_k127_3014813_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 329.0
TLS3_k127_3014813_3 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000002059 172.0
TLS3_k127_3015635_0 chemotaxis protein K03407 - 2.7.13.3 1.492e-194 629.0
TLS3_k127_3015635_1 COG0784 FOG CheY-like receiver K03413 - - 0.000000000000000000000000000000000000000007324 158.0
TLS3_k127_3015635_2 factor (Antagonist - - - 0.000007689 53.0
TLS3_k127_3015853_0 Histidine kinase - - - 4.929e-297 927.0
TLS3_k127_3015853_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006914 368.0
TLS3_k127_3015853_2 CobW/HypB/UreG, nucleotide-binding domain K03189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 344.0
TLS3_k127_3015853_3 PFAM HupE UreJ protein K03192 - - 0.00000000000000000000000000000000000000002349 160.0
TLS3_k127_3044654_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.915e-271 853.0
TLS3_k127_3044654_1 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000003707 226.0
TLS3_k127_3044654_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0001525 47.0
TLS3_k127_3052232_0 PFAM amidohydrolase 2 K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 464.0
TLS3_k127_3052232_1 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 454.0
TLS3_k127_3052232_2 AMP-binding enzyme K12508 - 6.2.1.34 0.0000000000000000003696 91.0
TLS3_k127_3058503_0 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009526 268.0
TLS3_k127_3058503_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000001002 235.0
TLS3_k127_307485_0 Sodium:solute symporter family K14393 - - 0.0 1151.0
TLS3_k127_307485_1 - - - - 0.0000000000000000000000000000000000000001154 153.0
TLS3_k127_307485_2 - - - - 0.0000000000000000000000000000000000000003122 156.0
TLS3_k127_307485_3 Domain of unknown function (DUF4212) - - - 0.00000000000000000000000000000000000009507 143.0
TLS3_k127_307485_4 - - - - 0.0000000000000000000000000007302 116.0
TLS3_k127_307485_5 - - - - 0.00000000000000000000000009614 109.0
TLS3_k127_307485_7 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.0000001065 54.0
TLS3_k127_3088336_0 zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000775 323.0
TLS3_k127_3088336_1 Phage tail sheath C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004416 284.0
TLS3_k127_3088336_2 adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000001776 233.0
TLS3_k127_3089627_0 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 615.0
TLS3_k127_3089627_1 COG2148 Sugar transferases involved in lipopolysaccharide synthesis K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 411.0
TLS3_k127_3089627_2 TIGRFAM chain length determinant protein EpsF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 358.0
TLS3_k127_3089627_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 308.0
TLS3_k127_3089627_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001315 264.0
TLS3_k127_3089627_5 polysaccharide export protein K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002117 258.0
TLS3_k127_3089627_6 Chain length determinant protein tyrosine kinase EpsG K08252 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002868 259.0
TLS3_k127_3089627_7 Domain of unknown function (DUF4252) - - - 0.0000000000000000000001643 100.0
TLS3_k127_3089627_8 BON domain - - - 0.0000000000000004392 85.0
TLS3_k127_3100616_0 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 465.0
TLS3_k127_3100616_1 Belongs to the glycosyl hydrolase 2 family K05970 - 3.1.1.53 0.0000000000000000000000000000000000000006602 155.0
TLS3_k127_3130854_0 Alternative oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 314.0
TLS3_k127_3130854_1 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000003226 162.0
TLS3_k127_3130854_2 - - - - 0.000000000000000000000000000001945 127.0
TLS3_k127_3131424_0 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 548.0
TLS3_k127_3131424_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 439.0
TLS3_k127_3131424_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 368.0
TLS3_k127_3131424_3 abc transporter atp-binding protein K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 354.0
TLS3_k127_3131424_4 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 319.0
TLS3_k127_3158105_0 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 428.0
TLS3_k127_3158105_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 337.0
TLS3_k127_3158105_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002346 284.0
TLS3_k127_3158105_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000001041 229.0
TLS3_k127_3158105_4 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000002163 168.0
TLS3_k127_3158105_5 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000001992 155.0
TLS3_k127_3187977_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 7.765e-251 782.0
TLS3_k127_3187977_1 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 343.0
TLS3_k127_3187977_10 - - - - 0.00000000000000009618 87.0
TLS3_k127_3187977_11 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000942 82.0
TLS3_k127_3187977_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 334.0
TLS3_k127_3187977_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 288.0
TLS3_k127_3187977_4 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000212 252.0
TLS3_k127_3187977_5 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000000000000000000000000000000000000003639 214.0
TLS3_k127_3187977_6 Domain of unknown function (DUF1841) - - - 0.00000000000000000000000000000000000000000000007997 173.0
TLS3_k127_3187977_7 Fis family transcriptional regulator K03413 - - 0.000000000000000000000000000000000000000000002055 171.0
TLS3_k127_3187977_8 CHRD domain - - - 0.00000000000000000000000000000000001907 142.0
TLS3_k127_3187977_9 MAPEG family - - - 0.0000000000000000000000000000001346 131.0
TLS3_k127_3190510_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 529.0
TLS3_k127_3190510_1 Predicted membrane protein (DUF2254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 464.0
TLS3_k127_3190510_2 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000001921 182.0
TLS3_k127_3190510_3 Tetratricopeptide repeat - - - 0.00000008364 62.0
TLS3_k127_3197437_0 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 620.0
TLS3_k127_3197437_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000000008018 205.0
TLS3_k127_3197437_2 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000328 197.0
TLS3_k127_319950_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.059e-315 977.0
TLS3_k127_319950_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000001791 81.0
TLS3_k127_3218199_0 PFAM monooxygenase FAD-binding K05712 - 1.14.13.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009325 504.0
TLS3_k127_3218199_1 Bacterial regulatory proteins, luxR family - - - 0.0000000000000000001441 98.0
TLS3_k127_3231238_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 513.0
TLS3_k127_3231238_1 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000002703 156.0
TLS3_k127_3245235_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 1.539e-218 697.0
TLS3_k127_3245235_1 Catalyzes the formation of succinyldiaminopimelate from N-succinyl-2-amino-6-ketopimelate K14267 - 2.6.1.17 0.000000000000000000000000000638 118.0
TLS3_k127_3248456_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 3.847e-219 698.0
TLS3_k127_3248456_1 Domain of unknown function (DUF4440) - - - 0.00000117 59.0
TLS3_k127_3248456_2 redox protein regulator of disulfide bond formation - - - 0.00001483 47.0
TLS3_k127_3250308_0 cAMP biosynthetic process K03641,K08282,K12132 - 2.7.11.1 9.336e-197 628.0
TLS3_k127_3252972_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 7.827e-225 717.0
TLS3_k127_3252972_1 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 485.0
TLS3_k127_3262289_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 573.0
TLS3_k127_3269840_0 - - - - 0.0000000000000000000000000000000000000000000000001539 183.0
TLS3_k127_3269840_1 - - - - 0.000000000000000000000000000000006037 143.0
TLS3_k127_3272086_0 Acyl-CoA thioesterase K10805 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007954 254.0
TLS3_k127_3272086_1 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.00000000000000000000000000000000001011 140.0
TLS3_k127_3272605_0 Putative esterase K07214 - - 2.914e-198 624.0
TLS3_k127_3272605_1 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 471.0
TLS3_k127_3272605_2 Belongs to the glycosyl hydrolase 13 family K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 436.0
TLS3_k127_3272605_3 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002561 282.0
TLS3_k127_3272605_4 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002006 253.0
TLS3_k127_3272605_5 PFAM Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000009882 229.0
TLS3_k127_3272605_6 carbohydrate transport - - - 0.00000000000000000000000000000000000000000000000000000000000001145 223.0
TLS3_k127_3272605_7 Alpha-L-arabinofuranosidase K01209 - 3.2.1.55 0.0000007485 55.0
TLS3_k127_3274497_0 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 383.0
TLS3_k127_3274497_1 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000296 284.0
TLS3_k127_3288995_0 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 3.672e-269 858.0
TLS3_k127_3288995_1 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 461.0
TLS3_k127_3288995_2 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 357.0
TLS3_k127_3288995_3 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 316.0
TLS3_k127_3288995_4 Helicase K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000003029 211.0
TLS3_k127_3288995_5 Peptidase M22 K14742 - - 0.000000000000000000000000000000000000000000005086 171.0
TLS3_k127_3288995_6 Prolyl oligopeptidase - - - 0.0008767 48.0
TLS3_k127_3299806_0 DoxX-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 453.0
TLS3_k127_3299806_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 474.0
TLS3_k127_3299806_2 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 373.0
TLS3_k127_3299806_3 Predicted integral membrane protein (DUF2269) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001928 239.0
TLS3_k127_3299806_4 Hemerythrin - - - 0.0000000000000000000000000000000000001364 150.0
TLS3_k127_3299806_5 - - - - 0.000000000000000000000000000000000003854 142.0
TLS3_k127_3333171_0 Cellulase N-terminal ig-like domain - - - 2.427e-317 984.0
TLS3_k127_3347767_0 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000002384 237.0
TLS3_k127_3347767_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000006394 106.0
TLS3_k127_3360936_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 314.0
TLS3_k127_3360936_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000006239 133.0
TLS3_k127_3360936_2 Sulfotransferase family - - - 0.000000000000000000000000000001255 134.0
TLS3_k127_3360936_3 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000137 112.0
TLS3_k127_3381397_0 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 397.0
TLS3_k127_3381397_1 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000006236 218.0
TLS3_k127_3381397_2 Belongs to the heme-copper respiratory oxidase family K00404 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 0.000000000000000000000000000000000000000000000000002751 183.0
TLS3_k127_3381397_3 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.000000000000001256 78.0
TLS3_k127_3388061_0 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K02567 - - 0.0 1368.0
TLS3_k127_3388061_1 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 388.0
TLS3_k127_3388061_2 Ferredoxin-type protein NapF K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.000000000001931 72.0
TLS3_k127_3388061_3 Nitrate reductase K02571 - - 0.0000000000209 65.0
TLS3_k127_3388061_4 protein involved in formation of periplasmic nitrate reductase K02570 - - 0.000000007829 64.0
TLS3_k127_3405033_0 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 381.0
TLS3_k127_3405033_1 ATPases associated with a variety of cellular activities K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 310.0
TLS3_k127_3405033_2 MlaD protein K02067 - - 0.00000000000000000000000000000000794 140.0
TLS3_k127_3405033_3 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000000000002474 90.0
TLS3_k127_3423253_0 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008387 390.0
TLS3_k127_3423253_1 Domain of unknown function (DUF4437) - - - 0.0000000000000000000000000000000000000000000000007298 179.0
TLS3_k127_3423253_2 COG0668 Small-conductance mechanosensitive channel K16052 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - 0.00000000000000002025 83.0
TLS3_k127_3423253_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000002368 72.0
TLS3_k127_3423253_4 Fe2 -dicitrate sensor, membrane component K07165 - - 0.0000009124 61.0
TLS3_k127_3430757_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2061.0
TLS3_k127_3430757_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0 1522.0
TLS3_k127_3432230_0 Trehalose utilisation - - - 0.0 1049.0
TLS3_k127_3432230_1 Xylose isomerase K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000003116 209.0
TLS3_k127_343743_0 Belongs to the IlvD Edd family K13875 - 4.2.1.25 2.06e-317 980.0
TLS3_k127_343743_1 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 494.0
TLS3_k127_343743_2 Short-chain dehydrogenase reductase sdr K22185 - 1.1.1.175 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 324.0
TLS3_k127_3441369_0 BlaR1 peptidase M56 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 353.0
TLS3_k127_3441369_1 COG1943 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000006818 210.0
TLS3_k127_3441369_2 Peptidase M56 - - - 0.000000000000000000000000000000000000000000000000004655 188.0
TLS3_k127_3441369_3 Penicillinase repressor - - - 0.000000000000000000000000000000000000000000002627 167.0
TLS3_k127_3458525_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K03778 - 1.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 449.0
TLS3_k127_3458525_1 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 285.0
TLS3_k127_3458525_2 L-lactate permease K03303 - - 0.0000000000000000000000000000000000000000000000000000000001798 209.0
TLS3_k127_3458525_3 Universal stress protein family K14055 - - 0.0000000000000000000000000000000005235 143.0
TLS3_k127_3460178_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.27e-224 706.0
TLS3_k127_3460178_1 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000005504 189.0
TLS3_k127_3460178_2 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000002743 101.0
TLS3_k127_3465297_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685 - - 1.082e-253 792.0
TLS3_k127_3465297_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000008945 75.0
TLS3_k127_3469061_0 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 312.0
TLS3_k127_3469061_1 Glutamine synthetase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 300.0
TLS3_k127_3469061_2 FAD dependent oxidoreductase K09471 - - 0.000000000000000000000000000000000000000000000000000000000000003686 227.0
TLS3_k127_3482532_0 Flagellar hook protein FlgE K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 499.0
TLS3_k127_3482532_1 Belongs to the flagella basal body rod proteins family K02388 - - 0.000000000000000000000000000000000000000000000000003984 184.0
TLS3_k127_3482532_2 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.00000000000000000000000000000000000000000003484 168.0
TLS3_k127_3482532_3 Flagellar basal body rod FlgEFG protein C-terminal K02391 - - 0.00000000000000002345 85.0
TLS3_k127_3499241_0 Participates in both transcription termination and antitermination K02600 - - 1.957e-218 689.0
TLS3_k127_3499241_1 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000009081 152.0
TLS3_k127_3499241_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000001667 121.0
TLS3_k127_3499241_3 - - - - 0.000001183 52.0
TLS3_k127_3509909_0 Na Pi-cotransporter K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 528.0
TLS3_k127_351254_0 Tryptophan halogenase K14266 - 1.14.19.9 9.831e-213 670.0
TLS3_k127_3522757_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001404 264.0
TLS3_k127_3522757_1 hydrolases or acyltransferases, alpha beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000001598 244.0
TLS3_k127_3522757_2 Carboxylesterase family - - - 0.00000000000000004722 88.0
TLS3_k127_3525783_0 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 472.0
TLS3_k127_352913_0 ABC-type nitrate sulfonate bicarbonate transport K15576,K22067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 415.0
TLS3_k127_352913_1 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 366.0
TLS3_k127_352913_2 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 367.0
TLS3_k127_352913_3 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001263 265.0
TLS3_k127_352913_4 response regulator receiver K07183 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001179 253.0
TLS3_k127_352913_5 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000003416 203.0
TLS3_k127_352913_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000004707 119.0
TLS3_k127_3535836_0 RNA-metabolising metallo-beta-lactamase K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 535.0
TLS3_k127_3535836_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 458.0
TLS3_k127_3535836_2 Domain of unknown function (DUF4154) - - - 0.0000000000000000000000005656 113.0
TLS3_k127_3535836_3 Domain of unknown function (DUF4154) - - - 0.00000000000000000000006534 106.0
TLS3_k127_3535836_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000006171 98.0
TLS3_k127_3535836_5 Universal stress protein - - - 0.00000000007646 70.0
TLS3_k127_354281_0 PQQ-like domain K00117 - 1.1.5.2 5.532e-302 948.0
TLS3_k127_354281_1 protein conserved in bacteria - - - 3.062e-243 766.0
TLS3_k127_354281_2 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 389.0
TLS3_k127_354281_3 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 357.0
TLS3_k127_354281_4 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000001025 228.0
TLS3_k127_354281_5 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000001903 186.0
TLS3_k127_3553834_0 PFAM Integrase catalytic region K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 393.0
TLS3_k127_3553834_1 Transposase K07483 - - 0.0000000000000000000000000000000000000000000000000000024 192.0
TLS3_k127_3553834_2 Transposase IS116/IS110/IS902 family - - - 0.00000000000004751 74.0
TLS3_k127_3563326_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 7.089e-264 818.0
TLS3_k127_3563326_1 glucose galactose transporter K02429 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 521.0
TLS3_k127_3563326_2 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 341.0
TLS3_k127_3563326_3 Transglycosylase associated protein - - - 0.000000000000000000000000000000000007251 137.0
TLS3_k127_3563326_4 PFAM Extensin family protein - - - 0.000000000000000000002695 93.0
TLS3_k127_3577616_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 457.0
TLS3_k127_3577616_1 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000004861 233.0
TLS3_k127_3577616_2 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000001064 188.0
TLS3_k127_3579217_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 1.219e-245 773.0
TLS3_k127_3579217_1 Winged helix DNA-binding domain K09927 - - 0.00000000000000000009783 91.0
TLS3_k127_3592135_0 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 1.378e-237 752.0
TLS3_k127_3592135_1 Gluconolactonase K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 487.0
TLS3_k127_3592135_2 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000000000001014 201.0
TLS3_k127_3592135_3 Domain of unknown function (DUF4112) - - - 0.0000000000000000000000000000000000005549 145.0
TLS3_k127_3592135_4 Fibronectin type III-like domain K05349 - 3.2.1.21 0.0007487 45.0
TLS3_k127_3594931_0 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 531.0
TLS3_k127_3594931_1 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 380.0
TLS3_k127_3594931_10 membrane - - - 0.00000000000000000000000001099 112.0
TLS3_k127_3594931_11 Domain of unknown function (DUF4266) - - - 0.0000000000000000002549 94.0
TLS3_k127_3594931_12 - - - - 0.000001176 59.0
TLS3_k127_3594931_13 Domain of unknown function (DUF4880) K07165 - - 0.000003825 58.0
TLS3_k127_3594931_14 Involved in the tonB-independent uptake of proteins K03641,K10117 - - 0.0002689 46.0
TLS3_k127_3594931_2 Alpha-L-fucosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 348.0
TLS3_k127_3594931_3 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 365.0
TLS3_k127_3594931_4 ApbE family K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 307.0
TLS3_k127_3594931_5 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001226 279.0
TLS3_k127_3594931_6 serine threonine protein kinase K00870,K12132 - 2.7.1.37,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002735 262.0
TLS3_k127_3594931_7 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000001378 226.0
TLS3_k127_3594931_8 Thioredoxin-like - - - 0.0000000000000000000000000000000000002458 149.0
TLS3_k127_3594931_9 DNA-templated transcription, initiation K03088,K03091 - - 0.00000000000000000000000000000002057 134.0
TLS3_k127_3608088_0 Histidine kinase - - - 0.0 1322.0
TLS3_k127_3608088_1 Sodium:solute symporter family K14393 - - 0.0 1080.0
TLS3_k127_3608088_2 response regulator receiver - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 344.0
TLS3_k127_3608088_3 Domain of unknown function (DUF4212) - - - 0.000000000000000000000000000007229 122.0
TLS3_k127_3608088_4 - K02221 - - 0.000000000000000003133 88.0
TLS3_k127_361839_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 521.0
TLS3_k127_361839_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 464.0
TLS3_k127_361839_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000001592 225.0
TLS3_k127_361839_11 - - - - 0.000000000000000000000000000000000000000000000000003619 189.0
TLS3_k127_361839_12 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000000000000000001027 181.0
TLS3_k127_361839_13 Biopolymer K03559 - - 0.00000000000000000000000000000000000002346 147.0
TLS3_k127_361839_15 Belongs to the UPF0250 family K09158 - - 0.00000000000000000005042 98.0
TLS3_k127_361839_2 Belongs to the peptidase S11 family K07258 GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 393.0
TLS3_k127_361839_3 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 387.0
TLS3_k127_361839_4 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 367.0
TLS3_k127_361839_5 PFAM Aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007338 348.0
TLS3_k127_361839_6 bacteriocin transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 290.0
TLS3_k127_361839_7 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001407 279.0
TLS3_k127_361839_8 PFAM Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002279 272.0
TLS3_k127_361839_9 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000002963 258.0
TLS3_k127_3639016_0 Lytic murein transglycosylase K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 586.0
TLS3_k127_3639016_1 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 539.0
TLS3_k127_3639016_10 MgtC family K07507 - - 0.00000000000000000000000000000000000000002009 160.0
TLS3_k127_3639016_11 polysaccharide deacetylase - - - 0.0000000000000000243 91.0
TLS3_k127_3639016_2 PFAM Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 438.0
TLS3_k127_3639016_3 Putative diguanylate phosphodiesterase K21023 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 346.0
TLS3_k127_3639016_4 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 317.0
TLS3_k127_3639016_5 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003578 239.0
TLS3_k127_3639016_6 Lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000007981 206.0
TLS3_k127_3639016_7 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000000000000000000000000000000000000000000000001973 203.0
TLS3_k127_3639016_8 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000003118 195.0
TLS3_k127_3639016_9 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.00000000000000000000000000000000000000000000000000265 200.0
TLS3_k127_3646724_0 COG1613 ABC-type sulfate transport system, periplasmic component K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 486.0
TLS3_k127_3646724_1 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 342.0
TLS3_k127_3646724_2 Phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001443 270.0
TLS3_k127_364674_0 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 484.0
TLS3_k127_364674_1 Hydrolase of alkaline phosphatase superfamily K07014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 440.0
TLS3_k127_3649696_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000004558 213.0
TLS3_k127_3649696_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000007752 130.0
TLS3_k127_3676486_0 Putative 2OG-Fe(II) oxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001528 264.0
TLS3_k127_3676486_1 tRNA methyltransferase complex GCD14 subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000003566 229.0
TLS3_k127_3676486_2 - - - - 0.00000000000000000000004563 102.0
TLS3_k127_3676486_3 Suppressor of fused protein (SUFU) - - - 0.0000000000000000425 83.0
TLS3_k127_3676486_4 Belongs to the UPF0270 family K09898 - - 0.00000000000001158 77.0
TLS3_k127_3687130_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 531.0
TLS3_k127_3687130_1 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 504.0
TLS3_k127_3687130_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 436.0
TLS3_k127_3687130_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000000000000000000000002204 180.0
TLS3_k127_3687453_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001,K00344 - 1.1.1.1,1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005495 396.0
TLS3_k127_3687453_1 glyoxalase III activity K02005 - - 0.0000000000000000000000000000000000000000000000000000004559 201.0
TLS3_k127_3687453_2 transcriptional regulator, ArsR family - - - 0.000000000000000000000000000000000000000004278 157.0
TLS3_k127_3687453_3 acyl-CoA dehydrogenase activity - - - 0.0000000000008218 81.0
TLS3_k127_3687453_4 LytTr DNA-binding domain - - - 0.00001242 49.0
TLS3_k127_3702546_0 Large extracellular alpha-helical protein K06894 - - 0.0 1115.0
TLS3_k127_3702546_1 Penicillin-Binding Protein C-terminus Family - - - 1.828e-201 641.0
TLS3_k127_3712443_0 ABC transporter K15578 - - 9.869e-250 784.0
TLS3_k127_3712443_1 Binding-protein-dependent transport system inner membrane component K15577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 451.0
TLS3_k127_3712443_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 402.0
TLS3_k127_3712443_3 - - - - 0.00000000000000000000000000000000000000001505 158.0
TLS3_k127_3712443_4 NMT1-like family K15576 - - 0.000000000002446 67.0
TLS3_k127_3720554_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1639.0
TLS3_k127_3720554_1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 - - 2.148e-248 777.0
TLS3_k127_3720554_2 Histidine ammonia-lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 449.0
TLS3_k127_3720554_3 PFAM histone deacetylase superfamily K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 400.0
TLS3_k127_3720554_4 - - - - 0.0000000000000000000000000000000000000000000001131 176.0
TLS3_k127_3732268_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 527.0
TLS3_k127_3732268_1 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 319.0
TLS3_k127_3732268_2 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001909 261.0
TLS3_k127_3732268_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.00000000000000000207 90.0
TLS3_k127_3733826_0 ABC-type sulfate transport system, permease component K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 415.0
TLS3_k127_3733826_1 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 376.0
TLS3_k127_3733826_2 TIGRFAM sulfate ABC transporter K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 352.0
TLS3_k127_3737413_0 SMART Nucleotide binding protein, PINc K07175 - - 7.596e-211 669.0
TLS3_k127_3737413_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 533.0
TLS3_k127_3737413_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008786 372.0
TLS3_k127_3737413_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005248 265.0
TLS3_k127_3737413_4 PFAM Amino acid-binding ACT K03567 - - 0.0000000000000000000000000000000000000000000000000000000008775 205.0
TLS3_k127_3737413_5 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000001615 202.0
TLS3_k127_3737413_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000002878 148.0
TLS3_k127_3737413_7 Domain of unknown function (DUF4184) - - - 0.0003371 47.0
TLS3_k127_3739479_0 Bacterial sugar transferase K00996,K16566 - 2.7.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005221 273.0
TLS3_k127_3739479_1 Polysaccharide biosynthesis/export protein K01991,K16552 - - 0.00000000000000000000000000000000000000000000002011 173.0
TLS3_k127_3740464_0 ankyrin repeats - - - 0.00000000000000000000000000000000000000000009262 162.0
TLS3_k127_3740464_1 - - - - 0.000000000000000005388 93.0
TLS3_k127_3740464_2 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00002301 49.0
TLS3_k127_3743525_0 Cystathionine beta-synthase K01697 - 4.2.1.22 2.525e-194 616.0
TLS3_k127_3743525_1 cystathionine K01758 - 4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 558.0
TLS3_k127_3743525_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000007981 263.0
TLS3_k127_3743525_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000001129 203.0
TLS3_k127_3743525_5 associated with various cellular activities K03924 - - 0.00000000000000000000006436 100.0
TLS3_k127_3761845_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 496.0
TLS3_k127_3761845_1 Methyltransferase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000001104 179.0
TLS3_k127_3793578_0 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000001598 178.0
TLS3_k127_3793578_1 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000005563 170.0
TLS3_k127_3802840_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 407.0
TLS3_k127_3802840_1 Dehydrogenase K13877 - 1.2.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 351.0
TLS3_k127_3802840_2 DEAD DEAH box helicase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 340.0
TLS3_k127_3802840_3 Alpha-L-arabinofuranosidase K01209 - 3.2.1.55 0.000000000000000000000000000000000000000000000000000000000003286 211.0
TLS3_k127_3802840_4 Protein of unknown function (DUF559) - - - 0.000000000000000000000000000000000001723 149.0
TLS3_k127_3802840_5 PFAM RES domain - - - 0.00000000000000000000000000000000004675 139.0
TLS3_k127_3802840_6 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.0000000000005317 70.0
TLS3_k127_3802840_7 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.000000004152 58.0
TLS3_k127_3802840_8 Protein of unknown function (DUF2384) - - - 0.000000005324 64.0
TLS3_k127_3814910_0 Predicted membrane protein (DUF2254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001474 293.0
TLS3_k127_3847448_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 395.0
TLS3_k127_3847448_1 Sigma-70, region 4 - - - 0.00000000000000000000000000000000000000000004137 170.0
TLS3_k127_3847448_2 - - - - 0.00000000000000000000000000005032 129.0
TLS3_k127_3847448_3 Bacterial Ig-like domain (group 3) - - - 0.0000000007005 68.0
TLS3_k127_3847838_0 PFAM Response regulator receiver domain K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003493 265.0
TLS3_k127_3847838_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000002222 102.0
TLS3_k127_3858599_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 293.0
TLS3_k127_3877404_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 2.195e-302 942.0
TLS3_k127_3877404_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 556.0
TLS3_k127_3877404_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 549.0
TLS3_k127_3877404_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 492.0
TLS3_k127_3877404_4 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 441.0
TLS3_k127_3877404_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 433.0
TLS3_k127_3877404_6 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000002523 259.0
TLS3_k127_3878055_0 4-oxalomesaconate hydratase K10220 - 4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 565.0
TLS3_k127_3878055_1 PFAM Amidohydrolase 2 K10221 - 3.1.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 492.0
TLS3_k127_3878055_2 protein conserved in bacteria K16514 GO:0003674,GO:0003824,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016853,GO:0016860,GO:0016863,GO:0017144,GO:0018918,GO:0018958,GO:0019336,GO:0019396,GO:0019439,GO:0019752,GO:0032787,GO:0042537,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 5.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 483.0
TLS3_k127_3878055_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04099,K04101 - 1.13.11.57,1.13.11.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 478.0
TLS3_k127_3878055_4 Domain of unknown function (DUF1932) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000168 256.0
TLS3_k127_3878055_5 Aldolase/RraA K10218 - 4.1.3.17 0.00000000000000000000000000000000000000000000000000000000000001181 218.0
TLS3_k127_3878055_6 Aromatic-ring-opening dioxygenase LigAB, LigA subunit K04100 - 1.13.11.8 0.0000000000000000000000000000000000000000000000000001774 188.0
TLS3_k127_3882960_0 Aminomethyltransferase folate-binding domain K15066 - 2.1.1.341 1.717e-212 669.0
TLS3_k127_3882960_1 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 573.0
TLS3_k127_3882960_2 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 396.0
TLS3_k127_3882960_3 COG0685 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000007589 195.0
TLS3_k127_3882960_4 Transcriptional regulator - - - 0.0000000000004701 70.0
TLS3_k127_3882960_5 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000001974 58.0
TLS3_k127_3924540_0 TIGRFAM diguanylate cyclase (GGDEF) domain K21023 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 591.0
TLS3_k127_3924540_1 TIGRFAM outer membrane autotransporter barrel - - - 0.000000000000000000000000000000008194 137.0
TLS3_k127_3947875_0 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003985 278.0
TLS3_k127_3947875_1 MerR, DNA binding K13639 - - 0.00000000000000000000000000000000000000000000000000000000001922 209.0
TLS3_k127_3947875_2 Protein involved in outer membrane biogenesis - - - 0.0000000000000000001633 100.0
TLS3_k127_3947875_3 - - - - 0.0000000002329 61.0
TLS3_k127_3947875_4 Hemerythrin HHE cation binding domain - - - 0.000002449 57.0
TLS3_k127_3953646_0 Calx-beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 631.0
TLS3_k127_3953646_1 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 524.0
TLS3_k127_3953646_2 cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 427.0
TLS3_k127_3953646_3 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008793 378.0
TLS3_k127_3953646_4 heptosyltransferase K12982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 318.0
TLS3_k127_3953646_5 PFAM glycosyl transferase family 9 - - - 0.0000000000000000000000000000000000000003964 153.0
TLS3_k127_3953646_6 - - - - 0.000000000000000000000000000000000000004436 155.0
TLS3_k127_3963192_0 NADP oxidoreductase, coenzyme f420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 306.0
TLS3_k127_3963192_1 PFAM phosphoesterase PA-phosphatase related K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000009975 181.0
TLS3_k127_3963192_2 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000001211 163.0
TLS3_k127_3963192_3 - - - - 0.0000000009505 67.0
TLS3_k127_3974221_0 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 616.0
TLS3_k127_3974221_1 Bacterial transcription activator, effector binding domain K13652,K13653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 385.0
TLS3_k127_3974221_2 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 328.0
TLS3_k127_3974221_3 Peptidase M56, BlaR1 - - - 0.00000000000000000000000000000000000000000000000000000000000000642 231.0
TLS3_k127_3974221_4 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000005537 225.0
TLS3_k127_3974221_5 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000000000000002173 171.0
TLS3_k127_3974221_6 Domain of unknown function (DUF4974) K07165 - - 0.0000000000000000000000000000354 130.0
TLS3_k127_3974221_7 Protein of unknown function (DUF1653) - - - 0.00000000000000000000004846 102.0
TLS3_k127_3974221_8 Domain of Unknown Function (DUF1080) - - - 0.00000000000000209 78.0
TLS3_k127_3980051_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1139.0
TLS3_k127_3980051_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 614.0
TLS3_k127_3980051_2 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.0000000000000000000000000000000000000000000000001105 188.0
TLS3_k127_3980051_3 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000001775 118.0
TLS3_k127_3980051_4 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0022402,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032506,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - 0.0000000000000000003288 100.0
TLS3_k127_3980915_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 484.0
TLS3_k127_3980915_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 342.0
TLS3_k127_3980915_2 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 332.0
TLS3_k127_3980915_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 309.0
TLS3_k127_3980915_4 Ribosomal protein L17 K02879 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000004503 171.0
TLS3_k127_3987455_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 512.0
TLS3_k127_3987455_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 407.0
TLS3_k127_3987455_2 Histidine kinase K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 371.0
TLS3_k127_3987455_3 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000001483 127.0
TLS3_k127_3989908_0 AAA domain - - - 0.000000000000000000000000000000000005085 143.0
TLS3_k127_3989908_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000008262 104.0
TLS3_k127_3997884_0 Transferase K02527 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 304.0
TLS3_k127_3997884_1 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 289.0
TLS3_k127_3997884_2 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008633 284.0
TLS3_k127_403988_0 Belongs to the citrate synthase family K01659 - 2.3.3.5 5.832e-200 628.0
TLS3_k127_403988_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 590.0
TLS3_k127_403988_2 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 400.0
TLS3_k127_403988_3 protease with the C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 358.0
TLS3_k127_403988_4 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 353.0
TLS3_k127_403988_5 2-methylcitrate dehydratase K01720 - 4.2.1.79 0.000000000000000000000000000000000000000000000000000000008138 199.0
TLS3_k127_403988_6 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000000000000000000005517 162.0
TLS3_k127_4050709_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.217e-271 852.0
TLS3_k127_4050709_1 permease protein K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 536.0
TLS3_k127_4050709_10 PFAM Uncharacterised protein family (UPF0093) K08973 - - 0.000000000000000000000000000000000000000000000888 169.0
TLS3_k127_4050709_11 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000001912 136.0
TLS3_k127_4050709_12 - - - - 0.0000000000000000000000000006354 124.0
TLS3_k127_4050709_2 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 506.0
TLS3_k127_4050709_3 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 449.0
TLS3_k127_4050709_4 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 416.0
TLS3_k127_4050709_5 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 393.0
TLS3_k127_4050709_6 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 336.0
TLS3_k127_4050709_7 Protein of unknown function, DUF484 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003099 288.0
TLS3_k127_4050709_8 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019222,GO:0019439,GO:0034353,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000001283 214.0
TLS3_k127_4050709_9 Iron--sulfur cluster insertion protein erpA K15724 - - 0.0000000000000000000000000000000000000000000000000003336 187.0
TLS3_k127_4059141_0 Periplasmic binding protein domain K01999 - - 3.639e-236 740.0
TLS3_k127_4059141_1 Histidine kinase - - - 3.694e-215 679.0
TLS3_k127_4059141_2 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 422.0
TLS3_k127_4059141_3 short chain amide porin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 397.0
TLS3_k127_4067943_0 Sodium/hydrogen exchanger family - - - 3.43e-206 647.0
TLS3_k127_4067943_1 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006866 256.0
TLS3_k127_4067943_2 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001744 238.0
TLS3_k127_4067943_3 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000000009648 157.0
TLS3_k127_4088607_0 Flagellar protein export ATPase FliI K02412 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 588.0
TLS3_k127_4088607_1 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 440.0
TLS3_k127_4088607_2 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 346.0
TLS3_k127_4088607_3 flagellar assembly protein FliH K02411 - - 0.00000000000000000000000000000000000000001015 162.0
TLS3_k127_4088607_4 Glyoxalase-like domain - - - 0.0000000000000000000000000000000003239 134.0
TLS3_k127_4088607_5 Flagellar hook-length control protein K02414 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - 0.000000000000000001348 96.0
TLS3_k127_4088607_6 Flagellar export protein FliJ K02413 - - 0.000005387 54.0
TLS3_k127_4102003_0 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000005422 179.0
TLS3_k127_4102003_1 O-Antigen Polymerase K02847 - - 0.0002314 53.0
TLS3_k127_4102910_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 8.054e-211 660.0
TLS3_k127_4102910_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781,K20023 - 4.2.1.156,4.2.1.42,5.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 542.0
TLS3_k127_4102910_2 Belongs to the Dps family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009409 287.0
TLS3_k127_4102910_3 Uncharacterized conserved protein (DUF2183) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005691 286.0
TLS3_k127_4102910_4 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000005847 173.0
TLS3_k127_4102910_5 UPF0056 inner membrane protein K05595 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000002844 74.0
TLS3_k127_4102910_6 - - - - 0.000001836 58.0
TLS3_k127_4102910_7 Domain of unknown function (DUF4124) - - - 0.000558 50.0
TLS3_k127_4117599_0 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000003725 160.0
TLS3_k127_4132121_0 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.0 1022.0
TLS3_k127_4132121_1 helix_turn_helix, mercury resistance K19591 - - 0.00000000000000000000000000000000148 131.0
TLS3_k127_4137045_0 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 346.0
TLS3_k127_4137045_1 Bacterial regulatory protein, Fis family K21405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004982 275.0
TLS3_k127_4137045_2 Coenzyme PQQ synthesis protein D (PqqD) K06138 - - 0.0000112 53.0
TLS3_k127_4147615_0 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000622 264.0
TLS3_k127_4147615_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000004776 153.0
TLS3_k127_4174463_0 RDD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 384.0
TLS3_k127_4174463_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 348.0
TLS3_k127_4174463_2 HDOD domain K03088 - - 0.000000000000000000000000000000000000000000000000000001019 198.0
TLS3_k127_4177332_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1285.0
TLS3_k127_4177332_1 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 366.0
TLS3_k127_4177332_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 293.0
TLS3_k127_4177332_3 Protein of unknown function (DUF3667) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 292.0
TLS3_k127_4177332_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.000000000000000000000000000000000000000000000000000000006721 202.0
TLS3_k127_4177332_5 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000001856 177.0
TLS3_k127_4192199_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 428.0
TLS3_k127_4192199_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 327.0
TLS3_k127_4192199_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000002751 228.0
TLS3_k127_4192199_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000004264 215.0
TLS3_k127_4192199_4 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000003439 188.0
TLS3_k127_4192199_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000005905 194.0
TLS3_k127_419905_0 serine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 297.0
TLS3_k127_419905_1 nadph quinone oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000007257 226.0
TLS3_k127_419905_2 - - - - 0.0000000000000000000000001452 118.0
TLS3_k127_4206651_0 Diguanylate cyclase - - - 4.803e-202 654.0
TLS3_k127_4209600_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1084.0
TLS3_k127_4209600_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 1.097e-203 643.0
TLS3_k127_4209600_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 480.0
TLS3_k127_4209600_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 407.0
TLS3_k127_4209600_4 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002731 257.0
TLS3_k127_4209600_5 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000007823 227.0
TLS3_k127_4209600_6 Could be involved in insertion of integral membrane proteins into the membrane K08998 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.0000000000000000000000000000722 117.0
TLS3_k127_4209600_7 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000001741 94.0
TLS3_k127_4209600_8 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000008126 69.0
TLS3_k127_4210682_0 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 340.0
TLS3_k127_4210682_1 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005391 259.0
TLS3_k127_4218848_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000001823 136.0
TLS3_k127_42218_0 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 432.0
TLS3_k127_42218_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001657 246.0
TLS3_k127_4239146_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 8.776e-265 833.0
TLS3_k127_4239146_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 451.0
TLS3_k127_4239146_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 346.0
TLS3_k127_4239146_3 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000004721 269.0
TLS3_k127_4239146_4 competence protein - - - 0.0000000000000000000000000000000000000000000000000000000000003254 220.0
TLS3_k127_4260345_0 regulator of chromosome condensation, RCC1 - - - 0.0000000000000000004275 102.0
TLS3_k127_4265670_0 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000192 215.0
TLS3_k127_4276743_0 TIGRFAM FeS assembly protein SufB K09014 - - 3.132e-268 831.0
TLS3_k127_4276743_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 572.0
TLS3_k127_4276743_2 Belongs to the class I fructose-bisphosphate aldolase family K01623 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 431.0
TLS3_k127_4276743_3 FeS assembly ATPase SufC K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008242 385.0
TLS3_k127_4276743_4 PFAM ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 346.0
TLS3_k127_4276743_5 FeS assembly protein SufD K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008489 348.0
TLS3_k127_4276743_6 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009774 263.0
TLS3_k127_4276743_7 TIGRFAM SUF system FeS K04488 - - 0.0000000000000000000000000000000000000000000000000007236 187.0
TLS3_k127_4276743_8 Transcriptional regulator - - - 0.0000000000000000000000000000000000001678 145.0
TLS3_k127_4276743_9 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008289,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000002031 69.0
TLS3_k127_4280973_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 355.0
TLS3_k127_4280973_1 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006304 270.0
TLS3_k127_4280973_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000001009 209.0
TLS3_k127_4280973_3 biopolymer transport protein - - - 0.0000000000000000000000000000000000000002463 157.0
TLS3_k127_4280973_4 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000001716 138.0
TLS3_k127_4280973_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000001616 125.0
TLS3_k127_4280973_6 - - - - 0.0000000000000001041 86.0
TLS3_k127_4280973_7 Tetratricopeptide repeat - - - 0.00000462 48.0
TLS3_k127_4298538_0 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006583 312.0
TLS3_k127_4298538_1 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000006547 214.0
TLS3_k127_4298538_2 Galactokinase galactose-binding signature K00849 - 2.7.1.6 0.00000000000002891 74.0
TLS3_k127_4299973_0 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 622.0
TLS3_k127_4299973_1 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000000000000000002484 174.0
TLS3_k127_4309069_0 amino acid K03294 - - 1.451e-258 804.0
TLS3_k127_4309069_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 571.0
TLS3_k127_4309069_10 Integral membrane protein TerC family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004603 312.0
TLS3_k127_4309069_11 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005656 292.0
TLS3_k127_4309069_12 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006127 267.0
TLS3_k127_4309069_13 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.00000000000000000000000000000000000000000000000000000000000000000000001386 250.0
TLS3_k127_4309069_14 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000002354 231.0
TLS3_k127_4309069_15 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000004839 200.0
TLS3_k127_4309069_16 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.00000000000000000000000000000000000000000000000008356 187.0
TLS3_k127_4309069_17 Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system K13628 - - 0.0000000000000000000000000000000000000000001511 161.0
TLS3_k127_4309069_18 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000001542 152.0
TLS3_k127_4309069_19 Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis K15539 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.000000000000000000000002352 114.0
TLS3_k127_4309069_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 518.0
TLS3_k127_4309069_20 NifU-like N terminal domain - - - 0.0000000000002827 76.0
TLS3_k127_4309069_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 464.0
TLS3_k127_4309069_4 Transfers a succinyl group from succinyl-CoA to L- serine, forming succinyl-L-serine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 434.0
TLS3_k127_4309069_5 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 431.0
TLS3_k127_4309069_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 427.0
TLS3_k127_4309069_7 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004898 351.0
TLS3_k127_4309069_8 Aminotransferase class I and II K00652,K01906 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030312,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.47,6.2.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 344.0
TLS3_k127_4309069_9 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 327.0
TLS3_k127_4320044_0 Protein of unknown function (DUF1343) - - - 6.877e-218 682.0
TLS3_k127_4320044_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 391.0
TLS3_k127_4320044_2 ABC transporter C-terminal domain K15738 - - 0.0000000000000000000000000000000000000000001078 164.0
TLS3_k127_4320044_3 - - - - 0.00000000000000000000000000000000000001992 150.0
TLS3_k127_4321189_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 9.652e-252 790.0
TLS3_k127_4321189_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000003532 128.0
TLS3_k127_4321189_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000007587 106.0
TLS3_k127_4329203_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 519.0
TLS3_k127_4329203_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 484.0
TLS3_k127_4329203_2 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000815 372.0
TLS3_k127_4329203_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 366.0
TLS3_k127_4329203_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 332.0
TLS3_k127_4329203_5 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 327.0
TLS3_k127_4329203_6 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001458 271.0
TLS3_k127_4329203_7 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 GO:0000166,GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043531,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000004017 136.0
TLS3_k127_4329203_8 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950,K13940 - 2.7.6.3,4.1.2.25 0.0000000001249 63.0
TLS3_k127_4335946_0 twitching motility protein K02670 - - 1.367e-194 613.0
TLS3_k127_4335946_1 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 606.0
TLS3_k127_4335946_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000003583 164.0
TLS3_k127_4339723_0 COG4149 ABC-type molybdate transport system, permease component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 305.0
TLS3_k127_4339723_1 PFAM ABC transporter K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000007019 207.0
TLS3_k127_4339723_2 ABC transporter, periplasmic molybdate-binding protein K02020 GO:0003674,GO:0005488,GO:0030973,GO:0043167,GO:0043168 - 0.000000000000000000000000000000000000000000002288 168.0
TLS3_k127_4347127_0 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000002358 213.0
TLS3_k127_4353337_0 nitrogen fixation sensor protein fixL K14986 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 460.0
TLS3_k127_4353337_1 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000331 289.0
TLS3_k127_4353337_2 part of global network that controls expression of aerobic respiratory terminal oxidases and carbon and nitrogen metabolic enzymes K14987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001092 273.0
TLS3_k127_4353337_3 - - - - 0.000000000000000000004393 96.0
TLS3_k127_4357237_0 Aminotransferase class-III K00819,K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.13,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 541.0
TLS3_k127_4357237_1 Phospholipid-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001121 271.0
TLS3_k127_4357237_2 X-Pro dipeptidyl-peptidase (S15 family) K07018 - - 0.00000000000000000000000000000000000000000000000000001993 195.0
TLS3_k127_4357237_3 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000004715 158.0
TLS3_k127_4357237_4 Belongs to the bacterial histone-like protein family - - - 0.00000000000000000000000000006043 119.0
TLS3_k127_4357237_6 Domain of unknown function (DUF4426) - - - 0.00000000000000000000000005641 113.0
TLS3_k127_4357237_7 YGGT family K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000001124 53.0
TLS3_k127_4357237_8 Molecular chaperone. Has ATPase activity K04079 - - 0.0000009685 50.0
TLS3_k127_4359682_0 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 402.0
TLS3_k127_4359682_1 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 289.0
TLS3_k127_4359682_2 Belongs to the Nudix hydrolase family K01515 - 3.6.1.13 0.000000000000000000000000000000004846 131.0
TLS3_k127_4359682_3 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000000000142 121.0
TLS3_k127_436095_0 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002401 270.0
TLS3_k127_436095_1 PFAM type IV pilus assembly PilZ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002188 246.0
TLS3_k127_4363102_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 - 2.6.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 557.0
TLS3_k127_4363102_1 Phytanoyl-CoA dioxygenase (PhyH) K10674 - 1.14.11.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 404.0
TLS3_k127_4363102_2 Transporter K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005488 272.0
TLS3_k127_4363102_3 Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant K06720 - 4.2.1.108 0.0000000000000000000000000000000000000000000000000000000006718 204.0
TLS3_k127_4363102_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000007724 156.0
TLS3_k127_4372300_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 489.0
TLS3_k127_4372300_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 351.0
TLS3_k127_4372300_2 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005369 276.0
TLS3_k127_4372300_3 Domain of unknown function (DUF1974) K06445 GO:0003674,GO:0003824,GO:0003995,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000003449 231.0
TLS3_k127_4372300_4 - K01992 - - 0.0000000000000000000000000000000000000000000000000000000003005 215.0
TLS3_k127_4372300_5 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.00000000000000000000000000000000000000000000000006817 182.0
TLS3_k127_4372300_6 abc transporter atp-binding protein K01990 - - 0.000000001356 59.0
TLS3_k127_4380760_0 Protein of unknown function, DUF255 K06888 - - 7.753e-252 797.0
TLS3_k127_4380760_1 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 488.0
TLS3_k127_4380760_10 3-hydroxyanthranilic acid dioxygenase K00452 - 1.13.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000007193 244.0
TLS3_k127_4380760_11 arylformamidase activity - - - 0.0000000000000000000000000000000000000000000000000000000004229 220.0
TLS3_k127_4380760_12 ApaG domain K06195 - - 0.00000000000000000000000000000000000000000000000000009515 189.0
TLS3_k127_4380760_13 Putative member of DMT superfamily (DUF486) K09922 - - 0.0000000000000000000000000000000000000000000000000001088 189.0
TLS3_k127_4380760_14 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.0000000000000000000000000000000000000000000009711 172.0
TLS3_k127_4380760_15 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000104 170.0
TLS3_k127_4380760_16 bis(5'-adenosyl)-triphosphatase activity - - - 0.00000000000000000000000000000000000000005638 157.0
TLS3_k127_4380760_17 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.00000000000000000000000000000000000000325 151.0
TLS3_k127_4380760_18 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000002156 141.0
TLS3_k127_4380760_19 PFAM TfoX N-terminal domain K07343 - - 0.0000000000001108 77.0
TLS3_k127_4380760_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 439.0
TLS3_k127_4380760_20 - - - - 0.00000000007618 68.0
TLS3_k127_4380760_3 SAM-dependent K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 445.0
TLS3_k127_4380760_4 FAD binding domain K00486 - 1.14.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 442.0
TLS3_k127_4380760_5 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 339.0
TLS3_k127_4380760_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 338.0
TLS3_k127_4380760_7 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 337.0
TLS3_k127_4380760_8 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001829 278.0
TLS3_k127_4380760_9 phenazine biosynthesis phzc phzf - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003567 277.0
TLS3_k127_4382603_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 0.0 1258.0
TLS3_k127_4382603_1 PFAM FAD binding domain in molybdopterin dehydrogenase K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 476.0
TLS3_k127_4382603_2 [2Fe-2S] binding domain K13483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 291.0
TLS3_k127_4382603_3 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000005084 134.0
TLS3_k127_4382603_4 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase - - - 0.000000000000000000000001094 107.0
TLS3_k127_4388306_0 chemotaxis protein K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 421.0
TLS3_k127_4388306_1 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 0.000000000000000000000000000000000000000000000000000001559 201.0
TLS3_k127_4388306_2 Two component signalling adaptor domain K02659 - - 0.0000000000000000000000000000000009745 137.0
TLS3_k127_4392225_0 Radical SAM superfamily K06871 - - 0.0000000000000000000000000000000000000000000000000000000000001079 226.0
TLS3_k127_4392225_1 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000000002856 158.0
TLS3_k127_4392431_0 Large extracellular alpha-helical protein K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009687 543.0
TLS3_k127_439642_0 Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 508.0
TLS3_k127_439642_1 Uncharacterized protein conserved in bacteria (DUF2200) - - - 0.0000000000000000000000000000000000000000000000000000000000000003082 221.0
TLS3_k127_4398096_0 COG2217 Cation transport ATPase K01533 - 3.6.3.4 3.066e-206 674.0
TLS3_k127_4398096_1 TIGRFAM cytochrome c oxidase accessory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 569.0
TLS3_k127_4398096_2 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007846 327.0
TLS3_k127_4398096_3 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 304.0
TLS3_k127_4398096_4 - - - - 0.00000000005356 66.0
TLS3_k127_4398096_5 Cytochrome oxidase maturation protein - - - 0.0000000005157 63.0
TLS3_k127_4398096_6 Cbb3-type cytochrome oxidase K00407 - - 0.00000001156 60.0
TLS3_k127_4405067_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 308.0
TLS3_k127_4414106_0 Hep Hag repeat protein - - - 0.000000000000000000000000000000000001685 153.0
TLS3_k127_4414106_1 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000002616 105.0
TLS3_k127_4414106_2 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000005436 67.0
TLS3_k127_4416591_0 Belongs to the flagella basal body rod proteins family K02396 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 486.0
TLS3_k127_4416591_1 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella - - - 0.000000000000000000000004086 109.0
TLS3_k127_4428954_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 476.0
TLS3_k127_4428954_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006779 248.0
TLS3_k127_4430601_0 LeuA allosteric (dimerisation) domain K01649 - 2.3.3.13 9.744e-222 694.0
TLS3_k127_4430601_1 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 GO:0000103,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 301.0
TLS3_k127_4436965_0 Major facilitator superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 437.0
TLS3_k127_4436965_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 329.0
TLS3_k127_4436965_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 291.0
TLS3_k127_4436965_3 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000001349 244.0
TLS3_k127_4436965_4 Domain of unknown function (DUF4124) - - - 0.00000000000000195 84.0
TLS3_k127_4464401_0 ABC transporter transmembrane region K06147,K11085 - - 3.57e-212 675.0
TLS3_k127_4464401_1 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 480.0
TLS3_k127_4464401_2 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303,K02304 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 467.0
TLS3_k127_4464401_3 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008631 463.0
TLS3_k127_4464401_4 Phosphatase K07093 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 449.0
TLS3_k127_4464401_5 in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon K13634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008141 393.0
TLS3_k127_4464401_6 Sulfite reductase K00381 - 1.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004399 270.0
TLS3_k127_4464401_7 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000226 268.0
TLS3_k127_4464401_8 alpha beta K06889 - - 0.0000000000000000000000000000000000000000000000000000000002626 220.0
TLS3_k127_4464401_9 Bacterial protein of unknown function (DUF934) - - - 0.000000000000000000000000000000001018 136.0
TLS3_k127_4477942_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000002775 225.0
TLS3_k127_448144_0 1,4-alpha-glucan branching enzyme activity K00700,K01187,K01236,K17734 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18,3.2.1.141,3.2.1.20 1.402e-258 812.0
TLS3_k127_448144_1 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 9.374e-242 769.0
TLS3_k127_448144_2 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 3.105e-196 634.0
TLS3_k127_448144_3 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000005495 184.0
TLS3_k127_448144_4 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000002265 147.0
TLS3_k127_448144_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000001643 72.0
TLS3_k127_4498827_0 Protein of unknown function DUF262 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 356.0
TLS3_k127_4498827_1 - - - - 0.00000000000000000000000000000000007078 141.0
TLS3_k127_4499087_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 502.0
TLS3_k127_4499087_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000003542 174.0
TLS3_k127_4499087_2 Alpha/beta hydrolase family - - - 0.0003248 47.0
TLS3_k127_4506534_0 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 350.0
TLS3_k127_4506534_1 PFAM Alcohol dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000167 207.0
TLS3_k127_4506534_2 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000000000000000000000000000000000000001007 190.0
TLS3_k127_4506534_3 Belongs to the ParB family K03497 - - 0.00000000002195 65.0
TLS3_k127_4507426_0 Peptidoglycan-binding domain 1 protein K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 440.0
TLS3_k127_4507426_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 414.0
TLS3_k127_4507426_2 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 306.0
TLS3_k127_4507426_3 Transport Permease Protein K01992 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000003364 142.0
TLS3_k127_4507426_4 membrane K02451,K03832 - - 0.000000000000002592 86.0
TLS3_k127_4513739_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 423.0
TLS3_k127_4513739_1 Domain of unknown function DUF21 K03699 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009136 326.0
TLS3_k127_4513739_2 Preprotein translocase subunit YajC K03210 - - 0.00000000000000000000000000000000003095 138.0
TLS3_k127_451445_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 334.0
TLS3_k127_451445_1 ECF sigma factor - - - 0.000000000000000000000000000000000000000000004717 171.0
TLS3_k127_4514503_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.887e-299 924.0
TLS3_k127_4514503_1 deiminase K05603 - 3.5.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008846 434.0
TLS3_k127_4514503_2 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 289.0
TLS3_k127_4514503_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K19694 - - 0.000000007842 63.0
TLS3_k127_4518146_0 ATPase domain of DNA mismatch repair MUTS family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 591.0
TLS3_k127_4518146_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 344.0
TLS3_k127_4535560_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 601.0
TLS3_k127_4535560_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 308.0
TLS3_k127_455249_0 PFAM major facilitator superfamily MFS_1 - - - 5.876e-196 624.0
TLS3_k127_455249_1 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 529.0
TLS3_k127_455249_2 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000002159 173.0
TLS3_k127_455249_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000002543 101.0
TLS3_k127_455249_4 Protein of unknown function (DUF4038) - - - 0.000000002177 59.0
TLS3_k127_455249_5 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000005706 59.0
TLS3_k127_455348_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 424.0
TLS3_k127_455348_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 306.0
TLS3_k127_455348_2 PFAM Mur ligase K11754 - 6.3.2.12,6.3.2.17 0.0000002191 54.0
TLS3_k127_4554407_0 Secretin and TonB N terminus short domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 613.0
TLS3_k127_4554407_1 prepilin-type N-terminal cleavage methylation K02456 - - 0.00000000000000000000000000000000000000000004059 165.0
TLS3_k127_4560375_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.248e-205 649.0
TLS3_k127_4560375_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 6.413e-198 631.0
TLS3_k127_4560375_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 459.0
TLS3_k127_4560375_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 437.0
TLS3_k127_4560375_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 394.0
TLS3_k127_4560375_5 Cytosol aminopeptidase family, catalytic domain K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 327.0
TLS3_k127_4560375_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000583 276.0
TLS3_k127_4560375_7 cystathionine K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000001118 212.0
TLS3_k127_4564739_0 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 1.036e-246 782.0
TLS3_k127_4564739_1 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 439.0
TLS3_k127_4564739_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 412.0
TLS3_k127_4564739_3 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001 242.0
TLS3_k127_4564739_4 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000000004006 212.0
TLS3_k127_4581273_0 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001755 243.0
TLS3_k127_4581273_1 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000003634 157.0
TLS3_k127_4581273_2 PBP superfamily domain K02040 - - 0.00000000000000000000000001828 121.0
TLS3_k127_4591930_0 radical SAM domain protein K03639,K15045 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 417.0
TLS3_k127_4591930_1 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 399.0
TLS3_k127_4591930_2 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009779 305.0
TLS3_k127_4591930_3 Fic/DOC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001799 235.0
TLS3_k127_4596926_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 524.0
TLS3_k127_4596926_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 520.0
TLS3_k127_4614752_0 PFAM PrkA AAA K07180 - - 5.565e-304 944.0
TLS3_k127_4614752_1 SpoVR like protein K06415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 566.0
TLS3_k127_4614752_2 DEAD DEAH box helicase K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 437.0
TLS3_k127_4614752_3 Belongs to the UPF0229 family K09786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 392.0
TLS3_k127_4614752_4 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004268 259.0
TLS3_k127_4614752_5 NmrA-like family - - - 0.00000000000000000000000000000000000000000001404 173.0
TLS3_k127_4614752_6 Outer membrane usher protein K07347 - - 0.000000000000000000000000000005869 135.0
TLS3_k127_4631425_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008262 471.0
TLS3_k127_4631425_1 belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000003471 132.0
TLS3_k127_4631425_2 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0005913 44.0
TLS3_k127_4644352_0 4-hydroxybenzoate K00481,K05712 GO:0000166,GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016705,GO:0016709,GO:0018659,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 1.14.13.127,1.14.13.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007926 529.0
TLS3_k127_4644352_1 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 338.0
TLS3_k127_4644352_2 Methyltransferase K02553,K10218 - 4.1.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 276.0
TLS3_k127_4655180_0 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 318.0
TLS3_k127_4655180_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 307.0
TLS3_k127_4655180_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000001682 199.0
TLS3_k127_4655180_3 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000002303 105.0
TLS3_k127_4664667_0 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000108 278.0
TLS3_k127_4664667_1 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000007364 180.0
TLS3_k127_4670006_0 Transposase, Mutator family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 593.0
TLS3_k127_4670006_1 Trehalase K01194 - 3.2.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 594.0
TLS3_k127_4670006_2 CobW/HypB/UreG, nucleotide-binding domain K03189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 347.0
TLS3_k127_4670006_3 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004816 280.0
TLS3_k127_4670006_4 Belongs to the BI1 family K19416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003225 256.0
TLS3_k127_4670006_5 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000001439 241.0
TLS3_k127_4670006_6 HupE UreJ protein K03192 - - 0.00000000000000000000000000000000000001294 152.0
TLS3_k127_4682478_0 ABC-type multidrug transport system ATPase and permease K06147 - - 8.057e-280 870.0
TLS3_k127_4682478_1 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003592 261.0
TLS3_k127_4686051_0 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000003693 255.0
TLS3_k127_4686051_1 TonB-dependent receptor plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000009836 234.0
TLS3_k127_4686051_2 RDD family - - - 0.0000000000000000000000000000000000000000000000000000001343 208.0
TLS3_k127_4686051_3 - - - - 0.000000000000000004928 85.0
TLS3_k127_4693434_0 Site-specific recombinase, DNA invertase Pin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 571.0
TLS3_k127_4699122_0 deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 306.0
TLS3_k127_4699122_1 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007725 287.0
TLS3_k127_4699122_2 COG3279 Response regulator of the LytR AlgR family K02477 - - 0.00000000000000000000000000000000006563 146.0
TLS3_k127_4705771_0 histidine kinase HAMP region domain protein K03406,K03776,K05874,K05875 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 409.0
TLS3_k127_4705771_1 Histidine kinase K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 398.0
TLS3_k127_4705771_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 403.0
TLS3_k127_4705771_3 helix_turn_helix, Lux Regulon K07689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005237 269.0
TLS3_k127_4705771_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000009456 245.0
TLS3_k127_4707846_0 acyl-CoA dehydrogenase activity K09456 - - 4.981e-199 635.0
TLS3_k127_4709548_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 1.544e-194 614.0
TLS3_k127_4709548_1 PFAM YCII-related - - - 0.00000000000000000000000000000000001093 139.0
TLS3_k127_4715948_0 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 293.0
TLS3_k127_4715948_1 Glycosyl transferase family group 2 - - - 0.000000000000000000000000072 115.0
TLS3_k127_4716369_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 358.0
TLS3_k127_4716369_1 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000002489 200.0
TLS3_k127_4716369_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000098 53.0
TLS3_k127_4729920_0 AbgT putative transporter family - - - 1.791e-203 647.0
TLS3_k127_4729920_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 392.0
TLS3_k127_4729920_2 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000001492 226.0
TLS3_k127_4729920_3 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000002045 196.0
TLS3_k127_4729920_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000006381 181.0
TLS3_k127_4729920_5 Involved in the tonB-independent uptake of proteins K03641 - - 0.0002741 50.0
TLS3_k127_4731366_0 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001607 242.0
TLS3_k127_4731366_1 bleomycin resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000005563 241.0
TLS3_k127_4731366_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000001691 242.0
TLS3_k127_4731366_3 Domain of unknown function (DUF4880) K07165 - - 0.00000000000000000000000000000000000000000000000000000002184 207.0
TLS3_k127_4731366_4 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.000000212 57.0
TLS3_k127_4731843_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 2.654e-239 762.0
TLS3_k127_4745476_0 Beta-galactosidase - - - 4.816e-264 844.0
TLS3_k127_4745476_1 Activator of aromatic catabolism - - - 3.688e-204 651.0
TLS3_k127_4745476_2 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000766 332.0
TLS3_k127_4745476_3 hmm pf00457 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 288.0
TLS3_k127_4745476_4 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000101 156.0
TLS3_k127_4745476_5 CAAX protease self-immunity K07052 - - 0.0006389 51.0
TLS3_k127_4760015_0 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 323.0
TLS3_k127_4760015_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 314.0
TLS3_k127_4760015_2 endonuclease activity - - - 0.000000000000002859 78.0
TLS3_k127_4771654_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000003186 222.0
TLS3_k127_4771654_1 - - - - 0.00001324 50.0
TLS3_k127_4774742_0 Ammonium transporter K03320 - - 7.734e-206 656.0
TLS3_k127_4774742_1 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 355.0
TLS3_k127_4774742_10 HemY domain protein K02498 - - 0.00000000000000000000000000000000000000000000000004929 201.0
TLS3_k127_4774742_11 Uroporphyrinogen III synthase K01719 - 4.2.1.75 0.000000000000000000000000000000000004371 146.0
TLS3_k127_4774742_12 Bacterial protein of unknown function (DUF883) - - - 0.000000000000000000008485 97.0
TLS3_k127_4774742_13 enzyme of heme biosynthesis K02496,K13543 - 2.1.1.107,4.2.1.75 0.00000000000000000001367 104.0
TLS3_k127_4774742_14 Membrane fusogenic activity K09806 - - 0.0000000000000000001533 91.0
TLS3_k127_4774742_15 membrane - - - 0.0000001146 59.0
TLS3_k127_4774742_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 324.0
TLS3_k127_4774742_3 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 302.0
TLS3_k127_4774742_4 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003001 289.0
TLS3_k127_4774742_5 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003234 289.0
TLS3_k127_4774742_6 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001816 253.0
TLS3_k127_4774742_7 Response regulator of the LytR AlgR family K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001643 246.0
TLS3_k127_4774742_8 Bacterial regulatory protein, arsR family - - - 0.000000000000000000000000000000000000000000000000000000000000000009615 228.0
TLS3_k127_4774742_9 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000001295 191.0
TLS3_k127_4791030_0 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 574.0
TLS3_k127_4791030_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 323.0
TLS3_k127_4791030_2 Pfam MotA TolQ ExbB proton channel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007646 274.0
TLS3_k127_4791030_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000008269 224.0
TLS3_k127_4791030_4 - - - - 0.0000000000000000000000000000000000000000000004896 183.0
TLS3_k127_4791030_5 HDOD domain - - - 0.000000000000000000000000000001432 140.0
TLS3_k127_4791239_0 Acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 600.0
TLS3_k127_4791239_1 Transcriptional regulatory protein, C terminal K02483,K07663 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 326.0
TLS3_k127_4791239_2 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001606 249.0
TLS3_k127_4791239_3 Protein of unknown function (DUF962) - - - 0.00000000000000000000000000000000000000000000000002972 190.0
TLS3_k127_4791239_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.000000000000000000000000000000000000000000009231 166.0
TLS3_k127_4791239_5 Histidine kinase - - - 0.00000000000000000000001339 106.0
TLS3_k127_4807468_0 PAS fold - - - 2.257e-217 691.0
TLS3_k127_4807468_1 DNA polymerase type-B family K02336 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 568.0
TLS3_k127_4807468_2 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004096 252.0
TLS3_k127_4807468_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000009417 143.0
TLS3_k127_4807468_4 cheY-homologous receiver domain - - - 0.000000000000000000000000000000009275 136.0
TLS3_k127_4807468_5 - - - - 0.000000000000004897 79.0
TLS3_k127_481797_0 Belongs to the peptidase S8 family K08651 - 3.4.21.66 3.791e-262 830.0
TLS3_k127_481797_2 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.000000000000000000000000000000000000000000000000000133 199.0
TLS3_k127_481797_3 TIGRFAM phage conjugal plasmid C-4 type zinc finger protein, TraR family - - - 0.00000000000000000000000000000000000000141 148.0
TLS3_k127_481797_4 YCII-related domain - - - 0.0000000000002133 76.0
TLS3_k127_4829309_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1247.0
TLS3_k127_4829309_1 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 454.0
TLS3_k127_4829309_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 434.0
TLS3_k127_4829309_3 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 309.0
TLS3_k127_4869385_0 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 476.0
TLS3_k127_4869385_1 YjbR - - - 0.000000000000000000000000000008561 129.0
TLS3_k127_4869385_2 thiolester hydrolase activity - - - 0.00000000000000003361 83.0
TLS3_k127_4869385_3 YjbR - - - 0.00000000000000121 87.0
TLS3_k127_4873100_0 GMC oxidoreductase - - - 4.791e-293 906.0
TLS3_k127_4873100_1 Universal stress protein family K14055 - - 0.000000000000000000000000000000000000000000000000004118 193.0
TLS3_k127_4873100_2 Gluconate 2-dehydrogenase subunit 3 - - - 0.00000000000000000000000000009984 123.0
TLS3_k127_4873100_3 PFAM Cytochrome C - - - 0.0000000000000000000000002773 114.0
TLS3_k127_4880905_0 Belongs to the ClpA ClpB family K03694 - - 1.822e-310 963.0
TLS3_k127_4880905_1 secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000001217 187.0
TLS3_k127_4880905_2 Type II secretion system protein C - - - 0.0000000000000000000000000000000000000000004744 169.0
TLS3_k127_4880905_3 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000005282 153.0
TLS3_k127_488288_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 371.0
TLS3_k127_488288_1 Domain of unknown function (DUF4398) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006362 276.0
TLS3_k127_488288_2 redox protein, regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000000157 158.0
TLS3_k127_488288_3 Crp-like helix-turn-helix domain - - - 0.000000000000000000000000000000000006214 138.0
TLS3_k127_488288_4 Domain of unknown function (DUF4398) - - - 0.00000000000000811 79.0
TLS3_k127_4900342_0 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 1.969e-229 732.0
TLS3_k127_4900342_1 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 379.0
TLS3_k127_4900822_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 1.008e-215 679.0
TLS3_k127_4900822_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 376.0
TLS3_k127_4900822_2 transcription elongation factor GreA GreB K06140 - - 0.000000000000000000000000000007421 126.0
TLS3_k127_4913044_0 Belongs to the enoyl-CoA hydratase isomerase family K00022,K07514 - 1.1.1.35,4.2.1.17,5.3.3.8 7.172e-302 940.0
TLS3_k127_4913044_1 Acetolactate synthase K01652 - 2.2.1.6 1.5e-281 878.0
TLS3_k127_4913044_10 Reprolysin (M12B) family zinc metalloprotease - - - 0.0000000000000000000000000000000000000004016 170.0
TLS3_k127_4913044_11 Alpha/beta hydrolase family - - - 0.00000000000000000000000000001642 130.0
TLS3_k127_4913044_12 Adenylate cyclase - - - 0.0003789 53.0
TLS3_k127_4913044_2 peptidase S9 - - - 4.594e-267 839.0
TLS3_k127_4913044_3 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 2.648e-196 621.0
TLS3_k127_4913044_4 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 358.0
TLS3_k127_4913044_5 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 347.0
TLS3_k127_4913044_6 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000001349 235.0
TLS3_k127_4913044_7 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001441 228.0
TLS3_k127_4913044_8 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000000000000000003951 183.0
TLS3_k127_4913044_9 acetolactate synthase, small K01653 - 2.2.1.6 0.0000000000000000000000000000000000000001924 158.0
TLS3_k127_4936223_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006151 314.0
TLS3_k127_4936223_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006376 310.0
TLS3_k127_4953142_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000992 509.0
TLS3_k127_4953142_1 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 304.0
TLS3_k127_4953142_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001853 287.0
TLS3_k127_4953142_3 glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000003964 265.0
TLS3_k127_4953142_4 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000006133 241.0
TLS3_k127_4953142_5 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000001481 74.0
TLS3_k127_4953142_6 - - - - 0.000000000005806 74.0
TLS3_k127_4959842_0 Receptor K02014 - - 8.931e-265 844.0
TLS3_k127_4959842_1 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008474 386.0
TLS3_k127_4959842_2 Receptor K02014 - - 0.000007168 48.0
TLS3_k127_4961595_0 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 545.0
TLS3_k127_4961595_1 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000007584 247.0
TLS3_k127_4961595_2 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000002578 204.0
TLS3_k127_4961595_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000001114 104.0
TLS3_k127_4993438_0 PFAM Phosphate-selective porin O K07221 - - 0.00000000000000000000000000000003001 134.0
TLS3_k127_4997895_0 - - - - 0.000000002123 70.0
TLS3_k127_5006187_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1446.0
TLS3_k127_5006187_1 Diphthamide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008163 263.0
TLS3_k127_5006187_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000001332 207.0
TLS3_k127_5006219_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 360.0
TLS3_k127_5006219_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 334.0
TLS3_k127_5027076_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 6.129e-211 662.0
TLS3_k127_5092656_0 Alpha-L-arabinofuranosidase K01209 - 3.2.1.55 3.462e-233 730.0
TLS3_k127_5092656_1 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 437.0
TLS3_k127_5092656_2 ABC-type sugar transport system, periplasmic component K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 436.0
TLS3_k127_5092656_3 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 383.0
TLS3_k127_5092656_4 Binding-protein-dependent transport systems inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 329.0
TLS3_k127_5092656_5 Belongs to the glycosyl hydrolase 43 family K06113 - 3.2.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 288.0
TLS3_k127_5092656_6 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000003922 232.0
TLS3_k127_5092656_7 Belongs to the glycosyl hydrolase family 6 K01179,K01181,K01218,K19668 - 3.2.1.4,3.2.1.78,3.2.1.8,3.2.1.91 0.00000000000000000000000000000000000000000000001631 184.0
TLS3_k127_5092656_8 Cobalamin (vitamin B12) biosynthesis CbiX protein - - - 0.000000000000000000000000000000000000000000004383 175.0
TLS3_k127_5092656_9 gluconolactonase activity - - - 0.00000000000000000000000000000000002734 140.0
TLS3_k127_5098474_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 7.346e-252 808.0
TLS3_k127_5098474_1 protein conserved in bacteria - - - 0.00000000000000000000001001 101.0
TLS3_k127_5112755_0 PFAM Mannitol dehydrogenase K00040 - 1.1.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 570.0
TLS3_k127_5112755_1 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 355.0
TLS3_k127_5116062_0 Malic enzyme K00029 - 1.1.1.40 0.0 1212.0
TLS3_k127_5116062_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 413.0
TLS3_k127_5116062_2 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 367.0
TLS3_k127_5116062_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 314.0
TLS3_k127_5116062_4 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000745 221.0
TLS3_k127_5116062_5 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000001656 219.0
TLS3_k127_5116062_6 MafB19-like deaminase K01487 - 3.5.4.3 0.00000000000000000000000000000000000000000000000000000001892 201.0
TLS3_k127_5116062_7 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000002311 177.0
TLS3_k127_5116062_8 Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins - - - 0.0000000000000000000000000000002556 126.0
TLS3_k127_5116062_9 YCII-related domain - - - 0.000000000000000000000000000001239 124.0
TLS3_k127_5124388_0 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 521.0
TLS3_k127_5124388_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 413.0
TLS3_k127_5124388_2 ABC transporter substrate-binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 367.0
TLS3_k127_5124388_3 ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 356.0
TLS3_k127_5124388_4 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002965 246.0
TLS3_k127_5124388_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000009855 243.0
TLS3_k127_5124388_6 Belongs to the UPF0307 family K09889 - - 0.0000000000000000000000000000008809 128.0
TLS3_k127_5125631_0 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 329.0
TLS3_k127_5125631_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 282.0
TLS3_k127_5125631_2 Thioesterase superfamily K19222 - 3.1.2.28 0.000000000000000000000000000000000000000000000001409 177.0
TLS3_k127_5127255_0 Histidine kinase - - - 8.409e-207 670.0
TLS3_k127_5127255_1 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 490.0
TLS3_k127_5127255_10 Probable zinc-ribbon domain - - - 0.0000000000000000000000000005323 116.0
TLS3_k127_5127255_11 - - - - 0.00000000000000007167 85.0
TLS3_k127_5127255_2 lactoylglutathione lyase activity K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 340.0
TLS3_k127_5127255_3 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 294.0
TLS3_k127_5127255_4 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001859 244.0
TLS3_k127_5127255_5 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000000000000000000000000000000000003516 198.0
TLS3_k127_5127255_6 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000001204 167.0
TLS3_k127_5127255_7 - - - - 0.00000000000000000000000000008536 119.0
TLS3_k127_5127255_8 - - - - 0.00000000000000000000000000008688 116.0
TLS3_k127_5127255_9 - - - - 0.0000000000000000000000000005277 117.0
TLS3_k127_5127567_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.365e-210 679.0
TLS3_k127_5127567_1 glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 496.0
TLS3_k127_5127567_2 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 459.0
TLS3_k127_5127567_3 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000001915 260.0
TLS3_k127_5127567_4 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000007397 65.0
TLS3_k127_5131136_0 Histidine kinase - - - 1.045e-219 708.0
TLS3_k127_5131136_1 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 550.0
TLS3_k127_5131136_11 Acetyltransferase (GNAT) domain - - - 0.000000005147 64.0
TLS3_k127_5131136_2 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 529.0
TLS3_k127_5131136_3 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 460.0
TLS3_k127_5131136_4 Tetrapyrrole (Corrin/Porphyrin) Methylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 397.0
TLS3_k127_5131136_5 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 368.0
TLS3_k127_5131136_6 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 343.0
TLS3_k127_5131136_7 protein conserved in bacteria K09912 - - 0.000000000000000000000000000000000000000000003323 169.0
TLS3_k127_5131136_8 Domain of unknown function (DUF4154) - - - 0.000000000000000000000000000000000023 142.0
TLS3_k127_5131136_9 Methyltransferase K00564 - 2.1.1.172 0.0000000000000000000000000000002695 124.0
TLS3_k127_5133633_0 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008876 550.0
TLS3_k127_5133633_1 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 490.0
TLS3_k127_5133633_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002461 224.0
TLS3_k127_5133633_3 Protein of unknown function (DUF1778) - - - 0.000000000000000000000000001261 115.0
TLS3_k127_5166681_0 Glycosyl hydrolases family 39 - - - 1.95e-239 752.0
TLS3_k127_5166681_1 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 548.0
TLS3_k127_5166681_2 Alpha-L-fucosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 299.0
TLS3_k127_5166681_3 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002173 258.0
TLS3_k127_5166681_4 Thioesterase - - - 0.000000000000000000000000000000000000000000000000000000002896 211.0
TLS3_k127_5177270_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 439.0
TLS3_k127_5177270_1 COG0303 Molybdopterin biosynthesis enzyme K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 333.0
TLS3_k127_5177270_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000263 264.0
TLS3_k127_5177270_3 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001055 246.0
TLS3_k127_5177270_4 MoaC family K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000001143 192.0
TLS3_k127_5177270_5 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase - - - 0.00000000000000000000000000000000000000000000000001128 188.0
TLS3_k127_5195496_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 389.0
TLS3_k127_5195496_1 Binding-protein-dependent transport system inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 358.0
TLS3_k127_5195496_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000001654 176.0
TLS3_k127_5199065_0 FAD binding domain K10676 - 1.14.13.20 7.47e-202 640.0
TLS3_k127_5199065_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 314.0
TLS3_k127_5199065_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002887 269.0
TLS3_k127_5199065_3 fumarate reductase K05898 - 1.3.99.4 0.000000000000000002773 85.0
TLS3_k127_5199065_4 FAD binding domain - - - 0.00000000006606 64.0
TLS3_k127_5202819_0 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 523.0
TLS3_k127_5202819_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 395.0
TLS3_k127_5202819_2 Nudix N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000005673 229.0
TLS3_k127_5202819_3 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000002657 198.0
TLS3_k127_5202819_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000001802 137.0
TLS3_k127_5202819_5 PDZ domain - - - 0.00000000000000000000007794 111.0
TLS3_k127_5229501_0 Cysteine-rich secretory protein family - - - 0.000000000000000000000000000000000000000000000000000000001017 211.0
TLS3_k127_5235343_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 555.0
TLS3_k127_5235343_1 Anthranilate synthase component I K01657,K01665 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 482.0
TLS3_k127_5235343_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 323.0
TLS3_k127_5235343_3 PFAM Aminotransferase, class IV K02619 - 4.1.3.38 0.00000000000000000000000000000000000000000000000000000000004384 216.0
TLS3_k127_5235343_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000001617 122.0
TLS3_k127_5235343_5 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000008232 91.0
TLS3_k127_5237622_0 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 564.0
TLS3_k127_5237622_1 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000001323 276.0
TLS3_k127_5237622_2 PFAM peptidase S16 lon domain protein K07157 - - 0.00000000000000000000000000000000000000000000001975 177.0
TLS3_k127_5237622_3 PFAM CAAX amino terminal protease family K07052 - - 0.0000000000000000000000000000000000000187 155.0
TLS3_k127_5237622_4 - - - - 0.000000000008141 72.0
TLS3_k127_5263312_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 5.973e-195 616.0
TLS3_k127_5263312_2 Belongs to the Dps family - - - 0.00000000000000000000002021 107.0
TLS3_k127_5263312_3 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000000000000008817 89.0
TLS3_k127_5263312_4 - - - - 0.00000000000000002769 90.0
TLS3_k127_5268064_0 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 GO:0000271,GO:0003674,GO:0003824,GO:0004475,GO:0005975,GO:0005976,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008905,GO:0008928,GO:0009058,GO:0009059,GO:0009242,GO:0009628,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046377,GO:0050896,GO:0070568,GO:0071704,GO:1901135,GO:1901137,GO:1901576 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 551.0
TLS3_k127_5268064_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000007948 203.0
TLS3_k127_5268064_2 S23 ribosomal protein - - - 0.000000000000000000257 93.0
TLS3_k127_5273340_0 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 439.0
TLS3_k127_5273340_1 PFAM Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003867 273.0
TLS3_k127_5273340_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000002714 264.0
TLS3_k127_5287791_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481,K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008505 526.0
TLS3_k127_5287791_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000000000009892 164.0
TLS3_k127_5287791_2 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000000001211 96.0
TLS3_k127_5300451_0 COG1538 Outer membrane protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 313.0
TLS3_k127_5300451_1 PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000005986 191.0
TLS3_k127_5300451_2 Sulfurtransferase - - - 0.0000000000000000000000009662 106.0
TLS3_k127_5315588_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 411.0
TLS3_k127_5315588_1 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 387.0
TLS3_k127_5315588_2 Cell shape determining protein MreB Mrl - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 310.0
TLS3_k127_5315588_3 N-Acetylmuramoyl-L-alanine amidase K11066,K12287 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000001339 234.0
TLS3_k127_5315588_5 polysaccharide biosynthetic process - - - 0.0000000000000000000000003551 119.0
TLS3_k127_5315588_6 response regulator - - - 0.00000000006138 68.0
TLS3_k127_5342380_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 580.0
TLS3_k127_5342380_1 glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 395.0
TLS3_k127_5342380_2 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 311.0
TLS3_k127_5342380_3 PFAM AsmA family K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001062 295.0
TLS3_k127_5342380_4 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000001745 148.0
TLS3_k127_5342380_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000002053 93.0
TLS3_k127_5344293_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000947 173.0
TLS3_k127_5344293_1 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.00000000000000000000000005641 113.0
TLS3_k127_5353202_0 modulator of DNA gyrase K03568 - - 2.087e-217 683.0
TLS3_k127_5353202_1 Type II secretory pathway component ExeA K02450,K12283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 329.0
TLS3_k127_5361362_0 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 371.0
TLS3_k127_5361362_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008032 244.0
TLS3_k127_5361362_2 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000001964 132.0
TLS3_k127_5361362_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.00000000004236 63.0
TLS3_k127_5361868_0 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 606.0
TLS3_k127_5361868_1 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 368.0
TLS3_k127_5361868_2 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 309.0
TLS3_k127_5361868_3 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 292.0
TLS3_k127_5361868_4 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000000002419 212.0
TLS3_k127_5361868_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000004596 164.0
TLS3_k127_5361868_6 Belongs to the UPF0149 family K09895 - - 0.000000000000000000000000001205 126.0
TLS3_k127_5361868_7 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000002226 109.0
TLS3_k127_5382052_0 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000007423 216.0
TLS3_k127_5382052_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000486 143.0
TLS3_k127_5385044_0 DNA ligase K01971 - 6.5.1.1 0.0 1151.0
TLS3_k127_5417310_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 599.0
TLS3_k127_5417310_1 enterobactin catabolic process K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 432.0
TLS3_k127_5417310_2 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 322.0
TLS3_k127_5417310_3 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000004603 250.0
TLS3_k127_5417310_4 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000005842 221.0
TLS3_k127_5417310_5 Periplasmic binding protein domain - - - 0.000000000000000000000000000000000000000000000000000000001379 215.0
TLS3_k127_5419477_0 Sugar (and other) transporter K08195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 366.0
TLS3_k127_5419477_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 293.0
TLS3_k127_5419477_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000239 269.0
TLS3_k127_5419477_3 nuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000003792 241.0
TLS3_k127_5419477_4 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000001911 166.0
TLS3_k127_5419477_5 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000003816 102.0
TLS3_k127_5419477_6 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000008089 99.0
TLS3_k127_5419477_7 SNARE associated Golgi protein - - - 0.0000000000001512 77.0
TLS3_k127_5423532_0 PEP-utilising enzyme, TIM barrel domain K01007 - 2.7.9.2 0.0 1198.0
TLS3_k127_5423532_1 Putative peptidoglycan binding domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 352.0
TLS3_k127_5423532_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 331.0
TLS3_k127_5423532_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 290.0
TLS3_k127_5423532_4 AAA domain K07028 - - 0.00000000000000000000000000000000000007929 149.0
TLS3_k127_5423532_5 Universal stress protein - - - 0.00000000000000000000000000000214 125.0
TLS3_k127_5428369_0 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 2.402e-211 672.0
TLS3_k127_5428369_1 Glycosyl Hydrolase Family 88 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 575.0
TLS3_k127_5428369_2 intracellular protease amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 412.0
TLS3_k127_5428369_3 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.00000000000000003207 81.0
TLS3_k127_5428369_4 Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen K00472 - 1.14.11.2 0.000000001572 67.0
TLS3_k127_5428369_5 type II secretion system protein K - - - 0.0004356 53.0
TLS3_k127_5429924_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.753e-246 772.0
TLS3_k127_5432251_0 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004523 265.0
TLS3_k127_5487591_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 7.971e-233 746.0
TLS3_k127_5487591_1 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009748 327.0
TLS3_k127_5487591_2 peptide chain release factor K15034 - - 0.000000000000000000000000000000000003279 143.0
TLS3_k127_5487591_3 small protein containing a coiled-coil domain - - - 0.000000000000002961 77.0
TLS3_k127_5506235_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 1.947e-310 962.0
TLS3_k127_5506235_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 6.719e-296 916.0
TLS3_k127_5506235_10 Negative regulator of sigma E activity K03597 - - 0.00001198 55.0
TLS3_k127_5506235_2 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 442.0
TLS3_k127_5506235_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003745 259.0
TLS3_k127_5506235_4 MucB/RseB C-terminal domain K03598 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0044464,GO:0045152 - 0.000000000000000000000000000000000000000000000001256 187.0
TLS3_k127_5506235_5 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.00000000000000000000000000006222 121.0
TLS3_k127_5506235_6 Succinate dehydrogenase, hydrophobic anchor subunit K00242 - - 0.0000000000000000000000000006561 123.0
TLS3_k127_5506235_7 Flavinator of succinate dehydrogenase K09159 - - 0.000000000001793 72.0
TLS3_k127_5506235_8 Protein of unknown function (DUF1674) - - - 0.00000000005895 63.0
TLS3_k127_5506235_9 PFAM glutaredoxin 2 - - - 0.000000001543 62.0
TLS3_k127_5508212_0 Secreted protein, containing von Willebrand factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 365.0
TLS3_k127_5508212_1 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000192 268.0
TLS3_k127_5508212_2 PFAM AMMECR1 domain protein K09141 - - 0.00000000000000000000000000000000000000000004952 170.0
TLS3_k127_5508212_3 - - - - 0.000000000000000000000000619 120.0
TLS3_k127_5508212_4 - - - - 0.000000000000000001557 96.0
TLS3_k127_5518048_0 DNA helicase K03654 - 3.6.4.12 7.313e-250 785.0
TLS3_k127_5518048_1 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 363.0
TLS3_k127_5518048_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 317.0
TLS3_k127_5518048_3 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 325.0
TLS3_k127_5518048_4 PilZ domain - - - 0.0000000000004962 72.0
TLS3_k127_5521260_0 Oxidoreductase K16044 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0070401,GO:0070402,GO:0097159,GO:0102497,GO:1901265,GO:1901363 1.1.1.371 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 297.0
TLS3_k127_5521260_1 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000005751 207.0
TLS3_k127_5523921_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 2.221e-217 703.0
TLS3_k127_5523921_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 387.0
TLS3_k127_5523921_2 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 325.0
TLS3_k127_5523921_3 ErfK YbiS YcfS YnhG K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 320.0
TLS3_k127_5523921_4 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000001667 201.0
TLS3_k127_5523921_5 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000001753 99.0
TLS3_k127_5523921_6 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000461 73.0
TLS3_k127_5523921_7 (Lipo)protein - - - 0.0004488 47.0
TLS3_k127_5583946_0 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 434.0
TLS3_k127_5583946_1 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 419.0
TLS3_k127_5583946_2 NADPH-quinone reductase (modulator of drug activity B) - - - 0.00000000000000000000000000000000000000000000000000000000000000003025 228.0
TLS3_k127_5583946_3 Putative phosphatase (DUF442) - - - 0.0000000000000000000000000000000000001933 147.0
TLS3_k127_5583946_4 transcriptional - - - 0.000000000000000000000000006411 113.0
TLS3_k127_5583946_5 Protein of unknown function (DUF2892) - - - 0.00000000000000000000006548 99.0
TLS3_k127_5583946_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000001488 87.0
TLS3_k127_5588226_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1380.0
TLS3_k127_5588226_1 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 597.0
TLS3_k127_5588226_2 FAD binding domain K10676 - 1.14.13.20 0.000000000001138 70.0
TLS3_k127_5594065_0 SMART ATPase, AAA type, core - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 310.0
TLS3_k127_5594065_1 Trypsin-like serine protease - - - 0.00000000000000000000000000000000000000000000000000000000005573 215.0
TLS3_k127_5594065_2 - - - - 0.000000000001043 74.0
TLS3_k127_5617277_0 serine threonine protein kinase K12132 - 2.7.11.1 1.844e-209 679.0
TLS3_k127_5617277_1 PFAM Type II secretion system protein E - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 512.0
TLS3_k127_5617277_2 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 450.0
TLS3_k127_5617277_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 416.0
TLS3_k127_5617277_4 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 309.0
TLS3_k127_5624158_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 623.0
TLS3_k127_5624158_1 Tetratricopeptide repeat - - - 0.0000004439 56.0
TLS3_k127_562775_0 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000001289 163.0
TLS3_k127_562775_1 COG0724 RNA-binding proteins (RRM domain) - - - 0.00000000000000000000000000003695 119.0
TLS3_k127_562775_2 Protein of unknown function (DUF2380) - - - 0.00000000000000000000000006191 117.0
TLS3_k127_56301_0 Protein of unknown function - - - 0.0000000000000000000000000000000000000000000000000000000000000000002336 246.0
TLS3_k127_56301_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.00000000000000000000000000000000000000002601 156.0
TLS3_k127_5634979_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 486.0
TLS3_k127_5634979_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000663 200.0
TLS3_k127_5634979_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000003535 190.0
TLS3_k127_5642326_0 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 373.0
TLS3_k127_5642326_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 327.0
TLS3_k127_5642326_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001782 286.0
TLS3_k127_5642326_3 signal peptide protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008791 280.0
TLS3_k127_5642326_4 Domain of unknown function (DUF4386) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004103 268.0
TLS3_k127_5642326_5 aminopeptidase N - - - 0.00000000000000000000000000000000000000000000000000000000000000000004933 246.0
TLS3_k127_5642326_6 CRP FNR family - - - 0.000000000000000000000000000000000000000000000000000000000000000002714 234.0
TLS3_k127_5642326_7 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000003004 244.0
TLS3_k127_5642326_8 - - - - 0.000000000000003885 76.0
TLS3_k127_5642326_9 COG1943 Transposase and inactivated derivatives - - - 0.0000001217 55.0
TLS3_k127_5646674_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 403.0
TLS3_k127_5646674_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 324.0
TLS3_k127_5646674_10 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000004351 149.0
TLS3_k127_5646674_11 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000009989 113.0
TLS3_k127_5646674_12 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000004446 106.0
TLS3_k127_5646674_13 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000007049 106.0
TLS3_k127_5646674_14 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000004069 74.0
TLS3_k127_5646674_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 289.0
TLS3_k127_5646674_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000011 278.0
TLS3_k127_5646674_4 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000121 258.0
TLS3_k127_5646674_5 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000008929 214.0
TLS3_k127_5646674_6 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000007143 213.0
TLS3_k127_5646674_7 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000005432 182.0
TLS3_k127_5646674_8 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000005512 161.0
TLS3_k127_5646674_9 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000000004194 159.0
TLS3_k127_5649897_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 4.03e-285 884.0
TLS3_k127_5649897_1 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003033 279.0
TLS3_k127_5659312_0 DNA-binding domain of Proline dehydrogenase K13821 - 1.2.1.88,1.5.5.2 0.0 1205.0
TLS3_k127_5659312_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 601.0
TLS3_k127_5659312_10 Belongs to the HSP15 family K04762 - - 0.0000000000000000000000000000785 120.0
TLS3_k127_5659312_11 phosphohistidine phosphatase, SixA K08296 - - 0.0000000004971 62.0
TLS3_k127_5659312_12 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000006635 61.0
TLS3_k127_5659312_2 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 551.0
TLS3_k127_5659312_3 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008652,GO:0008743,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046870,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 520.0
TLS3_k127_5659312_4 XdhC and CoxI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003169 268.0
TLS3_k127_5659312_5 MOSC domain protein beta barrel domain protein K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001715 259.0
TLS3_k127_5659312_6 PFAM Thioredoxin K05838 - - 0.000000000000000000000000000000000000000000000000000000000000006005 228.0
TLS3_k127_5659312_7 conserved protein UCP033924 - - - 0.000000000000000000000000000000000000000000000000005255 184.0
TLS3_k127_5659312_8 salt-induced outer membrane protein K07283 - - 0.00000000000000000000000000000000002271 147.0
TLS3_k127_5659312_9 Signal peptide peptidase K04773 GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - 0.000000000000000000000000000008197 124.0
TLS3_k127_5676315_0 Sodium/hydrogen exchanger family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 593.0
TLS3_k127_5676315_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 390.0
TLS3_k127_5676315_10 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000001948 156.0
TLS3_k127_5676315_11 - - - - 0.00000000000000000000000008728 112.0
TLS3_k127_5676315_12 - - - - 0.00000002209 60.0
TLS3_k127_5676315_13 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00006179 45.0
TLS3_k127_5676315_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 388.0
TLS3_k127_5676315_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 306.0
TLS3_k127_5676315_4 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 289.0
TLS3_k127_5676315_5 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000003104 230.0
TLS3_k127_5676315_6 RNA cap guanine-N2 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000001321 225.0
TLS3_k127_5676315_7 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000001111 211.0
TLS3_k127_5676315_8 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000001478 189.0
TLS3_k127_5676315_9 - - - - 0.00000000000000000000000000000000000000001699 167.0
TLS3_k127_568423_0 Cytochrome c K08738 - - 0.0000000000000000000000000000000002119 138.0
TLS3_k127_568423_2 Membrane - - - 0.000000000000000000000000005378 125.0
TLS3_k127_568423_3 EF hand - - - 0.000004342 55.0
TLS3_k127_5702499_0 receptor K16087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 382.0
TLS3_k127_5702499_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 361.0
TLS3_k127_5702499_2 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.0000000000000000000000000000000004807 143.0
TLS3_k127_5702499_3 Flagellar biosynthesis type III secretory pathway chaperone K02399 - - 0.00000003227 61.0
TLS3_k127_5702499_4 Hemin uptake protein hemP - - - 0.0000007898 56.0
TLS3_k127_5702499_5 COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor) K02398 - - 0.000002799 53.0
TLS3_k127_5706010_0 Outer Membrane Lipoprotein - GO:0008150,GO:0043900,GO:0050789,GO:0050794,GO:0065007,GO:1900190 - 0.000000000000000000000000000000000000000000000000000000000000001978 223.0
TLS3_k127_5706010_1 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000123 209.0
TLS3_k127_5706010_2 - - - - 0.000000000000000000000000000000000008338 143.0
TLS3_k127_5706010_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000003917 108.0
TLS3_k127_5706010_4 Protein of unknown function (DUF1648) - - - 0.00000000000002155 81.0
TLS3_k127_5718763_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000002186 75.0
TLS3_k127_5718986_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 491.0
TLS3_k127_5739177_0 TonB dependent receptor K16091 - - 5.454e-321 995.0
TLS3_k127_5739177_1 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 297.0
TLS3_k127_5739177_2 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 295.0
TLS3_k127_5739177_3 cephalosporin-C deacetylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008514 251.0
TLS3_k127_5739177_4 PRC-barrel domain - - - 0.0000000000000000000000000000000000000000004388 162.0
TLS3_k127_5744262_0 SMART AAA ATPase K08482 - - 3.135e-218 690.0
TLS3_k127_5744262_1 His Kinase A (phosphoacceptor) domain - - - 1.44e-214 687.0
TLS3_k127_5744262_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 626.0
TLS3_k127_5744262_3 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 466.0
TLS3_k127_5744262_4 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 383.0
TLS3_k127_5744262_5 membrane-bound metal-dependent K01993,K07038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 379.0
TLS3_k127_5744262_6 protein conserved in bacteria K09793 - - 0.00000000000000000000000000000000000000000000004227 175.0
TLS3_k127_5782060_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000009007 184.0
TLS3_k127_5782060_1 PFAM Surface antigen K07278 - - 0.00000000000000000000000000000000001714 143.0
TLS3_k127_5785564_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 447.0
TLS3_k127_5789674_0 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 489.0
TLS3_k127_5789674_1 Belongs to the flagella basal body rod proteins family K02396 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 471.0
TLS3_k127_5789674_2 Bacterial flagellin C-terminal helical region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 389.0
TLS3_k127_5789674_3 TIGRFAM Flagellar hook-associated protein 3 K02397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 327.0
TLS3_k127_5789674_4 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 317.0
TLS3_k127_5789674_5 Flagellar rod assembly protein muramidase FlgJ K02395 - - 0.000000000000000000000000000000000000000000000000000000000000000000001343 247.0
TLS3_k127_5789674_6 flagellar protein FliS K02422 - - 0.00000000000000000000000000002581 121.0
TLS3_k127_5789674_7 Atypical PilZ domain, cyclic di-GMP receptor - - - 0.000000000000000000000000442 112.0
TLS3_k127_5789674_8 FlaG protein K06603 - - 0.00000000000103 73.0
TLS3_k127_5791935_0 TonB-dependent receptor - - - 3.708e-309 976.0
TLS3_k127_5791935_1 Aldehyde dehydrogenase family K00128 - 1.2.1.3 7.283e-206 650.0
TLS3_k127_5791935_2 Pectate lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 545.0
TLS3_k127_5791935_3 Amb_all K01728 - 4.2.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 437.0
TLS3_k127_5791935_4 2-keto-4-pentenoate hydratase K02554 - 4.2.1.80 0.000001469 53.0
TLS3_k127_5814489_0 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 419.0
TLS3_k127_5814489_1 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 372.0
TLS3_k127_5814489_2 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000005364 231.0
TLS3_k127_5815291_0 DEAD DEAH box helicase K03724 - - 0.0 1424.0
TLS3_k127_5837556_0 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor - - - 1.623e-251 786.0
TLS3_k127_5840083_0 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 517.0
TLS3_k127_5840083_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 432.0
TLS3_k127_5845512_0 Belongs to the GARS family K01945,K13713 - 6.3.2.6,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 415.0
TLS3_k127_5845512_1 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000008273 214.0
TLS3_k127_5845512_2 - - - - 0.000000002576 62.0
TLS3_k127_5851715_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 575.0
TLS3_k127_5887202_0 AAA-like domain - - - 5.128e-253 803.0
TLS3_k127_5887202_1 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 496.0
TLS3_k127_5887202_10 Tetratricopeptide repeat - - - 0.0000000000000000000002785 105.0
TLS3_k127_5887202_11 Domain of unknown function (DUF4168) - - - 0.000002079 57.0
TLS3_k127_5887202_2 Extracellular solute-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 430.0
TLS3_k127_5887202_3 ATPase activity K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 402.0
TLS3_k127_5887202_4 sulfate ABC transporter K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 379.0
TLS3_k127_5887202_5 Sulfate ABC transporter, permease protein CysT K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 367.0
TLS3_k127_5887202_6 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 316.0
TLS3_k127_5887202_7 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001666 271.0
TLS3_k127_5887202_8 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000001224 170.0
TLS3_k127_5887202_9 DoxX - - - 0.00000000000000000000000000000000000000001248 160.0
TLS3_k127_5901601_0 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 529.0
TLS3_k127_5901601_1 Fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 349.0
TLS3_k127_5909773_0 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 486.0
TLS3_k127_5909773_1 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000000000004609 208.0
TLS3_k127_5909773_2 Transfers electrons from cytochrome c551 to cytochrome oxidase - - - 0.0000000000000000000000000000000000000000000000004992 179.0
TLS3_k127_5909773_3 hyperosmotic response K04065 - - 0.00000002801 60.0
TLS3_k127_5920305_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 4.795e-242 764.0
TLS3_k127_5920305_1 membrane K07148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 383.0
TLS3_k127_5920305_2 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 334.0
TLS3_k127_5920305_3 gntR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004999 283.0
TLS3_k127_5920305_4 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000000000000002787 170.0
TLS3_k127_593902_0 Vitamin K epoxide reductase family - - - 5.583e-321 1007.0
TLS3_k127_593902_1 Belongs to the heme-copper respiratory oxidase family K02274,K15408 - 1.9.3.1 2.263e-304 950.0
TLS3_k127_593902_2 mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 327.0
TLS3_k127_593902_3 Cytochrome C oxidase subunit II, periplasmic domain K02275,K02826 - 1.10.3.12,1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 302.0
TLS3_k127_593902_4 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004156 276.0
TLS3_k127_593902_5 Predicted membrane protein (DUF2231) - - - 0.000000000000000000000000000000000000000000000000000002823 194.0
TLS3_k127_593902_6 Uncharacterised protein family (UPF0093) - - - 0.0000000000000001803 85.0
TLS3_k127_5945787_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000004036 229.0
TLS3_k127_5945787_1 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000002987 220.0
TLS3_k127_5945787_2 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000001966 102.0
TLS3_k127_5945787_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0008007 44.0
TLS3_k127_5956853_0 Dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004159 269.0
TLS3_k127_5956853_1 Histidine kinase K19616 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001568 252.0
TLS3_k127_5956853_2 Cupin - - - 0.000000000001162 68.0
TLS3_k127_595753_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1179.0
TLS3_k127_5974986_0 efflux transmembrane transporter activity - - - 0.000000000000003003 78.0
TLS3_k127_5974986_1 RibD C-terminal domain - - - 0.0000000001231 61.0
TLS3_k127_5974986_2 Recombinase - - - 0.00000000127 63.0
TLS3_k127_5974986_3 RibD C-terminal domain - - - 0.000000001973 65.0
TLS3_k127_5974986_4 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00002547 53.0
TLS3_k127_6000712_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 501.0
TLS3_k127_6000712_1 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 370.0
TLS3_k127_6000712_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 298.0
TLS3_k127_6000712_3 Two component transcriptional regulator, winged helix family - - - 0.0000000000002596 78.0
TLS3_k127_6000712_4 PFAM cytochrome c, class I - - - 0.00000006736 56.0
TLS3_k127_6000712_5 - - - - 0.000001178 56.0
TLS3_k127_6000712_6 alginic acid biosynthetic process K10297 - - 0.000002544 52.0
TLS3_k127_6001428_0 Beta-xylanase K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 357.0
TLS3_k127_6001428_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - - 0.000000000000000000000000000000002501 134.0
TLS3_k127_6002205_0 COG0668 Small-conductance mechanosensitive channel K16052 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 402.0
TLS3_k127_6002205_1 Alpha Beta K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 319.0
TLS3_k127_6004196_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000002999 221.0
TLS3_k127_6004196_1 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000004652 195.0
TLS3_k127_6004196_2 Histidine kinase - - - 0.000000000000005409 81.0
TLS3_k127_6018425_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 559.0
TLS3_k127_6018425_1 subfamily IA, variant 1 K20862 - 3.1.3.102,3.1.3.104 0.000000000000000000000000000000000000008407 151.0
TLS3_k127_6030977_0 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000008401 203.0
TLS3_k127_6030977_1 Protein of unknown function (DUF1203) - - - 0.00000000000000000000000000000000000000000000000000007012 192.0
TLS3_k127_6030977_2 - - - - 0.00000000000000000001396 100.0
TLS3_k127_6030977_3 Catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge K00574 - 2.1.1.79 0.0000000239 55.0
TLS3_k127_6030977_4 SnoaL-like domain - - - 0.000000727 57.0
TLS3_k127_6038113_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 496.0
TLS3_k127_6080405_0 MASE1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001385 277.0
TLS3_k127_6080405_1 heme binding - - - 0.0000000000000000000000000000000000000000000000000000000000003563 235.0
TLS3_k127_6080405_2 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000004708 123.0
TLS3_k127_6080405_3 esterase K12686 - - 0.000000009192 57.0
TLS3_k127_6085360_0 type II secretion system protein E K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 520.0
TLS3_k127_6085360_1 Belongs to the GSP D family K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000002066 250.0
TLS3_k127_6085360_2 Type II secretion system K12510 - - 0.000000000000000000000000000000000000000000000006585 183.0
TLS3_k127_6085360_3 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.000000000000000000000000000000000000009136 156.0
TLS3_k127_6085360_4 type II secretion system protein K12511 - - 0.000000000000000008019 90.0
TLS3_k127_6085360_5 - - - - 0.0000000003602 70.0
TLS3_k127_6085360_6 - - - - 0.0006267 51.0
TLS3_k127_6097661_0 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008518 398.0
TLS3_k127_6097661_1 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 366.0
TLS3_k127_6097661_2 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000006556 135.0
TLS3_k127_6105948_0 COG0725 ABC-type molybdate transport system, periplasmic component K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007236 281.0
TLS3_k127_6105948_1 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000001445 115.0
TLS3_k127_6105948_2 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.00000000000000000000002374 104.0
TLS3_k127_61194_0 Dienelactone hydrolase family - - - 5.298e-282 880.0
TLS3_k127_61194_1 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.000000000000000000000000000000000000001758 153.0
TLS3_k127_61194_2 CcdB protein K19163 - - 0.00000000000000000000000000173 114.0
TLS3_k127_61194_3 Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid K19164 - - 0.0000000000000000001292 91.0
TLS3_k127_61194_4 - - - - 0.0000000000000002907 82.0
TLS3_k127_61194_5 - - - - 0.00000000001615 72.0
TLS3_k127_6124293_0 thiamine-containing compound biosynthetic process K02051 - - 1.139e-247 775.0
TLS3_k127_6124293_1 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 347.0
TLS3_k127_6124293_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 337.0
TLS3_k127_6124293_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000156 226.0
TLS3_k127_6124293_4 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000006415 165.0
TLS3_k127_6135437_0 Belongs to the transferase hexapeptide repeat family K00674 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007519 415.0
TLS3_k127_6135437_1 Succinyldiaminopimelate K14261,K14267 - 2.6.1.17 0.00000000000000000000000000000000002814 137.0
TLS3_k127_6135437_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000006964 54.0
TLS3_k127_6135485_0 Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 406.0
TLS3_k127_6135485_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 307.0
TLS3_k127_6135485_2 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009368 264.0
TLS3_k127_6139772_0 Putative ATPase subunit of terminase (gpP-like) - - - 0.00000000000000000000000002864 108.0
TLS3_k127_6146766_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 463.0
TLS3_k127_6146766_1 membrane K08981 - - 0.00000000000000000000000000000000000001959 154.0
TLS3_k127_6146766_2 Bacterial PH domain K09167 - - 0.00000000000000002059 92.0
TLS3_k127_6196710_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 1.434e-226 716.0
TLS3_k127_6196710_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 1.295e-204 649.0
TLS3_k127_6196710_2 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K13896,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 522.0
TLS3_k127_6196710_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 488.0
TLS3_k127_6196710_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 481.0
TLS3_k127_6202988_0 Outer membrane efflux protein K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009268 453.0
TLS3_k127_6202988_1 Efflux pump membrane transporter K03296,K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000004512 235.0
TLS3_k127_6202988_2 BetI-type transcriptional repressor, C-terminal - - - 0.000000000000000000000000000000000000004364 157.0
TLS3_k127_6210092_0 7TMR-DISM extracellular 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 490.0
TLS3_k127_6210092_1 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000128 209.0
TLS3_k127_6210092_2 FR47-like protein - - - 0.0000000000000000000000001064 112.0
TLS3_k127_6212833_0 COG0471 Di- and tricarboxylate transporters - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 589.0
TLS3_k127_6212833_1 Protein conserved in bacteria K09927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 438.0
TLS3_k127_6219363_0 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 494.0
TLS3_k127_6219363_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 306.0
TLS3_k127_6219363_2 - - - - 0.0000000001139 69.0
TLS3_k127_6220676_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000005184 169.0
TLS3_k127_6222489_0 Phosphoglucose isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 352.0
TLS3_k127_6222489_1 Sulfate permease family K03321 - - 0.0000000000000000000000000000000000000000000000000000000003145 206.0
TLS3_k127_6222489_2 Universal stress protein - - - 0.000000000000000000000000000000007886 139.0
TLS3_k127_6222489_3 P-type ATPase K01537 - 3.6.3.8 0.0001815 45.0
TLS3_k127_6227138_0 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 598.0
TLS3_k127_6227138_1 phosphoribosyl transferase K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000007302 230.0
TLS3_k127_6227138_2 BON domain K04065 - - 0.0000000000000000000000000000000000000000000000000000000316 204.0
TLS3_k127_6227138_3 SNARE associated Golgi protein - - - 0.00000000000000218 78.0
TLS3_k127_6227138_4 PEP-utilising enzyme, TIM barrel domain K01006,K01007,K02768,K08483,K11183 - 2.7.1.202,2.7.3.9,2.7.9.1,2.7.9.2 0.000000000002308 66.0
TLS3_k127_6227138_5 Bacterial protein of unknown function (DUF883) - - - 0.000001025 56.0
TLS3_k127_6230705_0 Phospholipase D. Active site motifs. K01115 - 3.1.4.4 5.437e-210 674.0
TLS3_k127_6230705_1 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000006285 267.0
TLS3_k127_6230705_2 rhodanese-related sulfurtransferase - - - 0.00000000000000000000000000000000000000000000000000000006122 203.0
TLS3_k127_6230705_3 Protein of unknown function, DUF599 - - - 0.00000000000000000000000000000000000000009454 155.0
TLS3_k127_6230705_4 Endonuclease/Exonuclease/phosphatase family - - - 0.00001194 56.0
TLS3_k127_6230706_0 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009563 373.0
TLS3_k127_6230706_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000003974 175.0
TLS3_k127_6230706_2 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000004042 167.0
TLS3_k127_6233160_0 Gluconolactonase K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 430.0
TLS3_k127_6233160_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 297.0
TLS3_k127_6233160_2 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000001532 224.0
TLS3_k127_6233160_3 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000005477 168.0
TLS3_k127_6236719_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 612.0
TLS3_k127_6236719_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 456.0
TLS3_k127_6236719_2 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 409.0
TLS3_k127_6236719_3 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008824 282.0
TLS3_k127_6236719_4 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000004981 207.0
TLS3_k127_6236719_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000007604 170.0
TLS3_k127_6244884_0 Allophanate hydrolase subunit 1 K01941 - 6.3.4.6 0.0 1516.0
TLS3_k127_6244884_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 490.0
TLS3_k127_6244884_2 TIGRFAM Urea carboxylase-associated protein 1 K09967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 330.0
TLS3_k127_6244884_3 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 327.0
TLS3_k127_6244884_4 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000877 332.0
TLS3_k127_6244884_5 Urea carboxylase-associated protein 2 K09967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 328.0
TLS3_k127_6245633_0 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003345 276.0
TLS3_k127_6245633_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000004862 153.0
TLS3_k127_6245633_2 Putative adhesin - - - 0.00000000000000000000000000000002309 141.0
TLS3_k127_6245633_3 CHASE2 - - - 0.000006434 48.0
TLS3_k127_6245633_4 - - - - 0.00004154 54.0
TLS3_k127_6256266_0 Splits dipeptides with a prolyl residue in the C- terminal position K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 463.0
TLS3_k127_6256266_1 2-oxopent-4-enoate hydratase activity K02554 - 4.2.1.80 0.0000000000000000000000000000000000000000000000000001579 195.0
TLS3_k127_6256266_2 -acetyltransferase - - - 0.000000000000002993 81.0
TLS3_k127_6260185_0 PFAM SpoVR family protein K06415 - - 5.867e-282 874.0
TLS3_k127_6260185_1 Belongs to the UPF0229 family K09786 - - 9.763e-217 678.0
TLS3_k127_6269600_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 520.0
TLS3_k127_6269600_1 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.0000000000000000000000000000000000003844 144.0
TLS3_k127_6269600_2 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000002225 139.0
TLS3_k127_6270039_0 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004753 271.0
TLS3_k127_6270039_1 Disulfide bond formation protein DsbB - - - 0.000000000000000000000000000000000000000000000000000000000000000000001189 242.0
TLS3_k127_6270039_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000002322 157.0
TLS3_k127_6270039_3 - - - - 0.000000000004861 68.0
TLS3_k127_6273153_0 7TMR-DISM extracellular 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 482.0
TLS3_k127_6273153_1 PFAM Glutathione-dependent formaldehyde-activating, GFA - - - 0.00000000000000000000000000000000000001146 149.0
TLS3_k127_6285906_0 Glycosyltransferase Family 4 - - - 0.0 1124.0
TLS3_k127_6285906_1 beta-1,4-mannooligosaccharide phosphorylase - - - 9.177e-225 703.0
TLS3_k127_6285906_2 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 521.0
TLS3_k127_6285906_3 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 427.0
TLS3_k127_6285906_4 Tryptophan halogenase K14266 - 1.14.19.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 293.0
TLS3_k127_6285906_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 291.0
TLS3_k127_6285906_6 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 293.0
TLS3_k127_6285906_7 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006 269.0
TLS3_k127_6285906_8 - K07004 - - 0.0000005775 63.0
TLS3_k127_6309439_0 May be involved in recombination K03554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001762 283.0
TLS3_k127_6309439_1 membrane - - - 0.0000000000000000000000000000001702 132.0
TLS3_k127_6309439_2 - - - - 0.0002508 50.0
TLS3_k127_6346449_0 pfkB family carbohydrate kinase K00874 - 2.7.1.45 4.653e-225 705.0
TLS3_k127_6346449_1 Belongs to the arginase family K01476,K01480,K12255,K18459 - 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 521.0
TLS3_k127_6346449_2 Aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 395.0
TLS3_k127_6346449_3 PFAM Ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 315.0
TLS3_k127_6346449_4 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000000000001375 222.0
TLS3_k127_6346449_5 O-acetylhomoserine K01740 - 2.5.1.49 0.00000000000000003964 81.0
TLS3_k127_63481_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 579.0
TLS3_k127_63481_1 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 463.0
TLS3_k127_63481_2 TIGRFAM alpha-L-glutamate ligase-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 379.0
TLS3_k127_63481_3 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000489 155.0
TLS3_k127_63481_4 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K18800 - - 0.000000000001425 70.0
TLS3_k127_6369287_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 539.0
TLS3_k127_6369287_1 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069,K11073 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 419.0
TLS3_k127_6369287_2 Binding-protein-dependent transport system inner membrane component K11071,K11075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 411.0
TLS3_k127_6369287_3 Binding-protein-dependent transport system inner membrane component K11070,K11074 - - 0.000000000000000000000000000000000000000000000000000000000000268 217.0
TLS3_k127_6379889_0 PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding K00256,K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 488.0
TLS3_k127_6379889_1 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000002423 217.0
TLS3_k127_6379889_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000001688 160.0
TLS3_k127_6379889_3 Domain of unknown function (DU1801) K05937 - - 0.0000000000000000000000000009097 116.0
TLS3_k127_6387753_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 432.0
TLS3_k127_6387753_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000003278 147.0
TLS3_k127_6388152_0 Peptidase M15 K02395 - - 0.0000000000000000000000000000005398 131.0
TLS3_k127_6388152_1 - - - - 0.0000000009158 64.0
TLS3_k127_6403860_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 333.0
TLS3_k127_6403860_1 - - - - 0.00000000000000000000000000000006508 130.0
TLS3_k127_6403914_0 N-acetyltransferase GCN5 - - - 0.0007284 46.0
TLS3_k127_6405709_0 sensor diguanylate cyclase phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 312.0
TLS3_k127_6428631_0 Circularly permuted ATP-grasp type 2 - - - 1.781e-239 749.0
TLS3_k127_6428631_1 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 388.0
TLS3_k127_6428631_2 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005217 264.0
TLS3_k127_6428631_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002484 253.0
TLS3_k127_6433510_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 436.0
TLS3_k127_6433510_1 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 340.0
TLS3_k127_6433510_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 323.0
TLS3_k127_6433510_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001178 250.0
TLS3_k127_6433510_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000009318 119.0
TLS3_k127_6433510_5 - - - - 0.000000000000000000000001838 109.0
TLS3_k127_6433510_6 - - - - 0.00000000000000000000008492 100.0
TLS3_k127_6443465_0 Transposase K07486 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007393 302.0
TLS3_k127_6443465_2 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000138 115.0
TLS3_k127_6443465_3 Protein of unknown function (DUF2442) - - - 0.000000000000001808 78.0
TLS3_k127_6444451_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1014.0
TLS3_k127_6444451_1 Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000000000000001702 185.0
TLS3_k127_6444451_2 ATP-dependent helicase K03579 - 3.6.4.13 0.0000000000000000000003646 95.0
TLS3_k127_6457029_0 Histidine Phosphotransfer domain K11527 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 377.0
TLS3_k127_6460816_0 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 370.0
TLS3_k127_6460816_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000007353 205.0
TLS3_k127_6460816_2 'PFAM Response regulator receiver - - - 0.000000000000000000007593 96.0
TLS3_k127_6480024_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 568.0
TLS3_k127_6480024_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 498.0
TLS3_k127_6480024_2 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 315.0
TLS3_k127_6480024_3 Elongation factor P--(R)-beta-lysine ligase K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 303.0
TLS3_k127_6480024_4 Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 288.0
TLS3_k127_6480024_5 FimV C-terminal K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001341 289.0
TLS3_k127_6480024_6 PFAM electron transport protein SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000003504 175.0
TLS3_k127_6480024_8 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000229 48.0
TLS3_k127_6486201_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1026.0
TLS3_k127_6486201_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 588.0
TLS3_k127_6486201_2 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007798 406.0
TLS3_k127_6486201_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 316.0
TLS3_k127_6486201_4 Response regulator in two-component regulatory system with KdpD K07667 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001321 268.0
TLS3_k127_6486201_5 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000008983 78.0
TLS3_k127_6520550_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008165 339.0
TLS3_k127_6520550_1 EF-hand domain pair - - - 0.0004311 48.0
TLS3_k127_6559530_0 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007711 533.0
TLS3_k127_6559530_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 519.0
TLS3_k127_6559530_2 RsbT co-antagonist protein rsbRD N-terminal domain K17763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 336.0
TLS3_k127_6559530_3 Serine/threonine phosphatases, family 2C, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 308.0
TLS3_k127_6559530_4 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) K17762 - - 0.0000000000000000000000000000000000000000000000000006909 186.0
TLS3_k127_6559530_5 Histidine kinase-like ATPases K17752 - 2.7.11.1 0.000000000000000000000000000000000000000000000000004805 184.0
TLS3_k127_6559530_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000003932 175.0
TLS3_k127_6559530_7 cheY-homologous receiver domain - - - 0.00000000000000003513 88.0
TLS3_k127_6560017_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 574.0
TLS3_k127_6560017_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 556.0
TLS3_k127_6560017_2 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 373.0
TLS3_k127_6560017_3 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 303.0
TLS3_k127_6560017_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000297 193.0
TLS3_k127_6560017_5 UPF0391 membrane protein - - - 0.000000000003485 72.0
TLS3_k127_6560017_6 - - - - 0.000001102 55.0
TLS3_k127_6560017_7 - - - - 0.0003269 51.0
TLS3_k127_6572829_0 Cytochrome c - - - 2.175e-296 930.0
TLS3_k127_6576361_0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 293.0
TLS3_k127_6576361_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000001021 230.0
TLS3_k127_6576361_2 PFAM methyltransferase - - - 0.0000000000000000000000000000000000000000000001234 178.0
TLS3_k127_6576361_3 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.000000000000000000000004115 110.0
TLS3_k127_6579782_0 ROK family - - - 0.00000000000000000000000000000000000000000000000000009094 190.0
TLS3_k127_6579782_1 membrane K14205 - 2.3.2.3 0.0000000000000000000000000000000000000005036 163.0
TLS3_k127_6579782_2 Gluconate 2-dehydrogenase subunit 3 - - - 0.000000000000000000000000000005094 122.0
TLS3_k127_6588184_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.68e-239 761.0
TLS3_k127_6588184_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 2.945e-203 642.0
TLS3_k127_6588184_10 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001065 184.0
TLS3_k127_6588184_11 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000003461 173.0
TLS3_k127_6588184_12 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000003231 137.0
TLS3_k127_6588184_13 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000008377 113.0
TLS3_k127_6588184_14 membrane - - - 0.000000000000000001018 97.0
TLS3_k127_6588184_15 protein conserved in bacteria K09937 - - 0.000000000009319 66.0
TLS3_k127_6588184_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 565.0
TLS3_k127_6588184_3 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 531.0
TLS3_k127_6588184_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 471.0
TLS3_k127_6588184_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008784,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0019842,GO:0030170,GO:0030203,GO:0034645,GO:0036094,GO:0036361,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0048037,GO:0050662,GO:0070279,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 347.0
TLS3_k127_6588184_6 phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 287.0
TLS3_k127_6588184_7 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001131 281.0
TLS3_k127_6588184_8 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002381 273.0
TLS3_k127_6588184_9 (FHA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000002264 224.0
TLS3_k127_6598347_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 333.0
TLS3_k127_6612738_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 452.0
TLS3_k127_6612738_1 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 400.0
TLS3_k127_6612738_2 ABC transporter K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 353.0
TLS3_k127_6612738_3 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 0.0000000000000000000000000000000000000000000003212 171.0
TLS3_k127_6612738_4 Sigma 54 modulation protein K05808 - - 0.0000000000000000000000000000000000001253 144.0
TLS3_k127_6612738_5 Belongs to the BolA IbaG family - - - 0.000000000000000000000122 100.0
TLS3_k127_6612738_6 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.00001111 55.0
TLS3_k127_6612738_7 lipopolysaccharide transmembrane transporter activity K02040,K11719 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0017089,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - 0.0001227 51.0
TLS3_k127_661591_0 ATPase (AAA K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 448.0
TLS3_k127_661591_1 LysM domain K06194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 298.0
TLS3_k127_661591_2 Lysin motif - - - 0.0004793 45.0
TLS3_k127_6623711_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00322 - 1.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 570.0
TLS3_k127_6623711_1 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 539.0
TLS3_k127_6623711_2 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.000000000000000000000000000000000000000000000000000004425 193.0
TLS3_k127_6626562_0 Elongation factor G, domain IV K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009428 267.0
TLS3_k127_6626562_1 Transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000003618 222.0
TLS3_k127_6639560_0 transport system involved in gliding motility, auxiliary component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 521.0
TLS3_k127_6639560_1 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 365.0
TLS3_k127_6639560_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 322.0
TLS3_k127_6639560_3 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000000004198 185.0
TLS3_k127_6650215_0 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 492.0
TLS3_k127_6650215_1 Serine hydrolase involved in the detoxification of formaldehyde K01070,K09795 - 3.1.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 408.0
TLS3_k127_6650215_2 transporter K07552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 315.0
TLS3_k127_6650215_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002305 262.0
TLS3_k127_6665941_1 Type ii and iii secretion system protein - - - 0.000000000000000000000000000001077 131.0
TLS3_k127_6665941_2 - - - - 0.000000000000000000000000000007774 123.0
TLS3_k127_6670838_0 PFAM Transposase IS66 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001398 257.0
TLS3_k127_6705455_0 amidase activity K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 486.0
TLS3_k127_6705455_1 - - - - 0.000004126 54.0
TLS3_k127_6734511_0 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 358.0
TLS3_k127_6734511_1 Belongs to the GST superfamily K00799 GO:0000302,GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0009636,GO:0010035,GO:0016740,GO:0016765,GO:0042221,GO:0042493,GO:0042542,GO:0044424,GO:0044464,GO:0046677,GO:0050896,GO:1901700 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000002602 243.0
TLS3_k127_6734511_2 Tannase and feruloyl esterase K21105 - 3.1.1.102 0.000000000000000002428 85.0
TLS3_k127_6776866_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.517e-276 861.0
TLS3_k127_6776866_1 Helicase K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 443.0
TLS3_k127_6776866_2 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 340.0
TLS3_k127_6776866_3 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000009549 229.0
TLS3_k127_6776866_4 Peptidase family M28 - - - 0.0000000000000000000001601 100.0
TLS3_k127_6776866_5 TIGRFAM conserved repeat domain - - - 0.000000000000004901 83.0
TLS3_k127_6831162_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 2.178e-218 692.0
TLS3_k127_6831162_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 590.0
TLS3_k127_6831162_2 ABC-type dipeptide transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 351.0
TLS3_k127_6836439_0 cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 512.0
TLS3_k127_6836439_1 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000005545 130.0
TLS3_k127_6836439_2 Domain of unknown function (DUF4386) - - - 0.0000000000000000000009769 101.0
TLS3_k127_6841670_0 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 314.0
TLS3_k127_6841670_1 MlaA lipoprotein K04754 - - 0.000000000000000000000000001082 116.0
TLS3_k127_6843095_0 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 474.0
TLS3_k127_6843095_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 409.0
TLS3_k127_6843095_2 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 335.0
TLS3_k127_6843095_3 DinB family - - - 0.000000000000000000000000000000000000000000000000000000000002267 216.0
TLS3_k127_6843095_4 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000002626 216.0
TLS3_k127_6843095_5 methyltransferase activity - - - 0.00000000000000000000000000000003469 131.0
TLS3_k127_6843095_6 6-phosphogluconolactonase K07404 - 3.1.1.31 0.000001833 53.0
TLS3_k127_6853293_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.554e-196 620.0
TLS3_k127_6853293_1 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000006712 232.0
TLS3_k127_6853293_2 binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000007121 175.0
TLS3_k127_6853293_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000004078 163.0
TLS3_k127_6853293_4 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000001896 153.0
TLS3_k127_6853293_5 TIGRFAM ribosomal protein L30 K02907 - - 0.0000000000000001509 80.0
TLS3_k127_6853293_6 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000004487 65.0
TLS3_k127_6869553_0 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000000000000000000000000002602 189.0
TLS3_k127_6869553_1 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.0000000000000000000000000007605 125.0
TLS3_k127_6869553_2 General secretion pathway protein J K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.00000000000000000000004513 101.0
TLS3_k127_6874350_0 Circadian clock protein K08482 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 579.0
TLS3_k127_6874350_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 409.0
TLS3_k127_6874350_2 KaiB K08481 - - 0.00000000000000000000000000000000000000000001088 164.0
TLS3_k127_6910687_0 transporter - - - 2.865e-281 878.0
TLS3_k127_6910687_1 PFAM peptidase M2, peptidyl-dipeptidase A K01283 - 3.4.15.1 4.83e-234 738.0
TLS3_k127_6910687_2 POT family K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 496.0
TLS3_k127_6910687_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 299.0
TLS3_k127_6910687_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000001548 70.0
TLS3_k127_6910687_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000003819 71.0
TLS3_k127_6911840_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 572.0
TLS3_k127_6911840_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000003541 128.0
TLS3_k127_6911840_2 MltA-interacting MipA family protein K07274 - - 0.000000000007236 75.0
TLS3_k127_6913441_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 293.0
TLS3_k127_6913441_1 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000009856 252.0
TLS3_k127_6913441_2 D,D-heptose 1,7-bisphosphate phosphatase - - - 0.0000000000000000000000000000000000000000000000000183 181.0
TLS3_k127_6935319_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.486e-279 865.0
TLS3_k127_6935319_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 343.0
TLS3_k127_6935319_2 PFAM Cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.000000000000000000000000000000000000000001434 161.0
TLS3_k127_6935319_3 Integral membrane protein (DUF2244) - - - 0.00000000005485 70.0
TLS3_k127_6935319_4 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.197 0.0007936 44.0
TLS3_k127_6938321_0 PFAM Pyrrolo-quinoline quinone K00114 - 1.1.2.8 0.0 1056.0
TLS3_k127_6938321_1 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007587 486.0
TLS3_k127_6938321_2 Bacterial regulatory protein, Fis family K21405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 470.0
TLS3_k127_6938321_3 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000181 284.0
TLS3_k127_6938321_4 - - - - 0.0000000000000000000000000000001082 128.0
TLS3_k127_6946589_0 hydrolase, family 65, central catalytic - - - 1.943e-204 649.0
TLS3_k127_6946589_1 PIN domain - - - 0.000000000000000000007163 98.0
TLS3_k127_696400_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1037.0
TLS3_k127_696400_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 460.0
TLS3_k127_696400_2 chromosome segregation K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 352.0
TLS3_k127_696400_3 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 315.0
TLS3_k127_696400_4 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000005151 245.0
TLS3_k127_696400_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000008187 237.0
TLS3_k127_696400_6 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000001972 229.0
TLS3_k127_696400_7 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000118 224.0
TLS3_k127_696400_8 Translation initiation factor K03113 - - 0.0000000000000000000000000000001492 129.0
TLS3_k127_696400_9 - - - - 0.00003883 53.0
TLS3_k127_6966500_0 amidase activity K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 4.969e-235 751.0
TLS3_k127_6966500_1 amidase activity K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 2.06e-220 704.0
TLS3_k127_6989532_0 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 370.0
TLS3_k127_6989532_1 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 366.0
TLS3_k127_6996904_0 OmpA family K03286 - - 0.0000000000000000000000003319 109.0
TLS3_k127_7002851_0 Allophanate hydrolase K01457 - 3.5.1.54 1.715e-214 684.0
TLS3_k127_7002851_1 Allophanate hydrolase subunit 2 K01941,K01959 - 6.3.4.6,6.4.1.1 0.0000000000000000000000001234 110.0
TLS3_k127_7006964_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 2.545e-198 631.0
TLS3_k127_7006964_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 3.035e-197 624.0
TLS3_k127_7006964_2 Belongs to the peptidase S1C family K04691,K04771,K04772 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 332.0
TLS3_k127_7006964_3 Cytochrome C1 family K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006552 265.0
TLS3_k127_7006964_4 Stringent starvation protein A K03599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001901 250.0
TLS3_k127_7006964_5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000007166 241.0
TLS3_k127_7009761_0 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 576.0
TLS3_k127_7009761_1 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 510.0
TLS3_k127_7009761_10 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000002603 127.0
TLS3_k127_7009761_11 cheY-homologous receiver domain - - - 0.0000000000001646 78.0
TLS3_k127_7009761_12 FG-GAP repeat protein - - - 0.000000000003651 72.0
TLS3_k127_7009761_13 DNA-templated transcription, initiation - - - 0.0001212 54.0
TLS3_k127_7009761_2 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 394.0
TLS3_k127_7009761_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 361.0
TLS3_k127_7009761_4 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004364 272.0
TLS3_k127_7009761_5 Protein of unknown function (DUF3014) - - - 0.00000000000000000000000000000000000000000000000000000001379 209.0
TLS3_k127_7009761_6 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000001102 183.0
TLS3_k127_7009761_7 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000009458 171.0
TLS3_k127_7009761_8 Autotransporter beta-domain - - - 0.000000000000000000000000000000000000000002167 179.0
TLS3_k127_7009761_9 Response regulator receiver domain - - - 0.000000000000000000000000009699 113.0
TLS3_k127_7018956_0 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 342.0
TLS3_k127_7018956_1 PFAM TadE family protein - - - 0.0000000000000000000000000000000000000000000000000001073 201.0
TLS3_k127_7018956_2 - - - - 0.0000000000000000008093 90.0
TLS3_k127_7023415_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 403.0
TLS3_k127_7023415_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 348.0
TLS3_k127_7023415_2 PhnA Zinc-Ribbon K06193 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000006281 184.0
TLS3_k127_7023415_3 MAPEG family - - - 0.00000000000000000000000000000000000000000000000009803 183.0
TLS3_k127_7023415_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000005855 85.0
TLS3_k127_704540_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007559 348.0
TLS3_k127_704540_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003198 274.0
TLS3_k127_704540_2 polysaccharide export protein K01991 - - 0.00000000000000000000000000000000000000000000000003569 185.0
TLS3_k127_704540_3 AAA domain - - - 0.00000000000000000000000000000000000000000000000007458 188.0
TLS3_k127_704540_4 protein involved in exopolysaccharide biosynthesis - - - 0.000000000000000000000000000000000000000000001745 185.0
TLS3_k127_704540_5 Protein conserved in bacteria - - - 0.00000007845 64.0
TLS3_k127_7046570_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 484.0
TLS3_k127_7046570_1 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 362.0
TLS3_k127_7046570_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 0.0000489 46.0
TLS3_k127_7058246_0 Belongs to the glycosyl hydrolase 43 family K01198,K01209 - 3.2.1.37,3.2.1.55 8.568e-235 737.0
TLS3_k127_7058246_1 PFAM oxidoreductase domain protein - - - 3.88e-199 635.0
TLS3_k127_7058246_2 Trehalose utilisation K15538,K21132 - 3.2.1.130,3.2.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009026 550.0
TLS3_k127_7058246_3 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 432.0
TLS3_k127_7058246_4 Cupin 2, conserved barrel domain protein K00971,K19547 - 2.7.7.13,5.3.3.19 0.0001373 48.0
TLS3_k127_7059384_0 PFAM 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 1.226e-212 680.0
TLS3_k127_7059384_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005935 354.0
TLS3_k127_7059384_2 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003928 279.0
TLS3_k127_7059384_3 MTH538 TIR-like domain (DUF1863) - - - 0.00000004023 57.0
TLS3_k127_7060140_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.797e-240 755.0
TLS3_k127_7060140_1 OmpA-like transmembrane domain - - - 0.00001612 52.0
TLS3_k127_7063987_0 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008646 283.0
TLS3_k127_7063987_1 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001593 269.0
TLS3_k127_7072802_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1189.0
TLS3_k127_7072802_1 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000002464 229.0
TLS3_k127_7072802_2 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000000000000000000000000307 133.0
TLS3_k127_707510_0 PFAM Carbon starvation protein CstA K06200 - - 0.0 1045.0
TLS3_k127_707510_1 translation initiation factor activity K06996 - - 0.0000000000000000000000000000000000000000000000000000001258 212.0
TLS3_k127_707510_2 alpha-ribazole phosphatase activity K15634 - 5.4.2.12 0.00000000000000000000000000002041 127.0
TLS3_k127_707510_3 Selenoprotein, putative - - - 0.00000057 53.0
TLS3_k127_7078044_0 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 438.0
TLS3_k127_7078044_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 305.0
TLS3_k127_7078044_2 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001003 245.0
TLS3_k127_7078044_3 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000003149 199.0
TLS3_k127_7078044_4 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000008311 171.0
TLS3_k127_7078044_5 Glycosyl hydrolases family 16 - - - 0.0000000000000000000000000000000000000003127 162.0
TLS3_k127_7078044_6 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000001761 151.0
TLS3_k127_7078044_7 Protein conserved in bacteria - - - 0.000000000000000000000005408 118.0
TLS3_k127_7088285_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1017.0
TLS3_k127_7088285_1 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 625.0
TLS3_k127_7088285_10 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000000002655 167.0
TLS3_k127_7088285_11 Domain of unknown function (DUF4390) - - - 0.00000000000000000000000000000001979 133.0
TLS3_k127_7088285_2 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 453.0
TLS3_k127_7088285_3 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 379.0
TLS3_k127_7088285_4 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 378.0
TLS3_k127_7088285_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 359.0
TLS3_k127_7088285_6 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 345.0
TLS3_k127_7088285_7 Response regulator receiver K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 296.0
TLS3_k127_7088285_8 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 293.0
TLS3_k127_7088285_9 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000003556 254.0
TLS3_k127_709304_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1678.0
TLS3_k127_709304_1 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 377.0
TLS3_k127_709304_2 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 356.0
TLS3_k127_709304_3 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 342.0
TLS3_k127_709304_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000002176 190.0
TLS3_k127_7099688_0 peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 621.0
TLS3_k127_7099688_1 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 605.0
TLS3_k127_7101456_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 1.607e-199 633.0
TLS3_k127_7101456_1 Pyrimidine nucleoside phosphorylase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 555.0
TLS3_k127_7101456_2 Sodium ABC transporter permease K09696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 511.0
TLS3_k127_7101456_3 abc transporter atp-binding protein K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 393.0
TLS3_k127_7101456_4 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 326.0
TLS3_k127_7101456_5 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000001468 229.0
TLS3_k127_7101456_6 Diguanylate cyclase K03320 - - 0.00000000000000000000000000000000000001065 166.0
TLS3_k127_7101456_7 helix_turn_helix, arabinose operon control protein - - - 0.000000000262 65.0
TLS3_k127_7105595_0 Fis family transcriptional regulator K10941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 435.0
TLS3_k127_7105595_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 350.0
TLS3_k127_7105595_2 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000000000000000006071 108.0
TLS3_k127_7105595_3 Atypical PilZ domain, cyclic di-GMP receptor - - - 0.000001791 50.0
TLS3_k127_7108858_0 Heparinase II/III N-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002288 277.0
TLS3_k127_7108858_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000001355 117.0
TLS3_k127_7110041_0 Glycosyl hydrolase, family 20, catalytic domain - - - 0.0 1128.0
TLS3_k127_7117876_0 COG4206 Outer membrane cobalamin receptor protein K16092 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015267,GO:0015318,GO:0015889,GO:0015893,GO:0016020,GO:0016021,GO:0019904,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 422.0
TLS3_k127_7117876_1 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 304.0
TLS3_k127_7117876_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002348 259.0
TLS3_k127_7117876_3 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000008524 243.0
TLS3_k127_7117876_4 PFAM LppC K07121 - - 0.00000000000000000000000000000000000000000000000000000000000000005435 233.0
TLS3_k127_7117876_5 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000022 118.0
TLS3_k127_7118091_0 Tryptophan halogenase K14266 - 1.14.19.9 5.544e-227 712.0
TLS3_k127_7118091_1 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000963 550.0
TLS3_k127_7118091_2 - - - - 0.00000000005031 74.0
TLS3_k127_7118642_0 Outer membrane receptor - - - 0.0 1036.0
TLS3_k127_7118642_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 5.974e-220 704.0
TLS3_k127_7118642_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 588.0
TLS3_k127_7118642_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000005148 200.0
TLS3_k127_7118642_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000003395 160.0
TLS3_k127_7118642_5 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000005096 119.0
TLS3_k127_7118642_6 Major facilitator Superfamily - - - 0.00001271 48.0
TLS3_k127_7135958_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 1.72e-229 715.0
TLS3_k127_7135958_1 Pro-apoptotic serine protease nma111. Source PGD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 393.0
TLS3_k127_7135958_2 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000001187 130.0
TLS3_k127_7140510_0 TIGRFAM FeS assembly SUF system protein SufT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000332 265.0
TLS3_k127_7140510_1 Rieske-like [2Fe-2S] domain K05710,K18087 - - 0.00000000000000000000000000001254 120.0
TLS3_k127_7140510_2 Phosphoglycerate mutase family K08296 - - 0.0000000000000002477 81.0
TLS3_k127_7151640_0 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 562.0
TLS3_k127_7152270_0 amidase activity K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 1.172e-203 652.0
TLS3_k127_7152270_1 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000005192 215.0
TLS3_k127_7152270_2 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000000000006634 190.0
TLS3_k127_7152270_3 - - - - 0.0000000000000004177 84.0
TLS3_k127_7152940_0 receptor - - - 0.0 1299.0
TLS3_k127_7152940_1 fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 507.0
TLS3_k127_7152940_2 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000091 294.0
TLS3_k127_7152940_3 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000000005541 198.0
TLS3_k127_7152940_4 Transcriptional regulator - - - 0.00000002278 55.0
TLS3_k127_7163146_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 513.0
TLS3_k127_7163146_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 317.0
TLS3_k127_7163146_2 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008114 260.0
TLS3_k127_7163146_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000002137 236.0
TLS3_k127_7163146_4 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000001013 145.0
TLS3_k127_7169079_0 Di-haem oxidoreductase, putative peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 469.0
TLS3_k127_7169079_1 Imelysin K07231 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 316.0
TLS3_k127_7185711_0 PFAM Peptidase family M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 364.0
TLS3_k127_7185711_1 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006812 272.0
TLS3_k127_7185711_2 Protein of unknown function (DUF938) - - - 0.00000000000000000000000000000000000000000000000000000000000000001331 231.0
TLS3_k127_7185711_3 Protein of unknown function (DUF1249) K09920 - - 0.000000000000000000000000001342 118.0
TLS3_k127_7188426_0 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 313.0
TLS3_k127_7188426_1 Protein of unknown function (DUF3025) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004348 267.0
TLS3_k127_7188426_2 OmpA-like transmembrane domain - - - 0.00000000000000000001153 99.0
TLS3_k127_7188426_3 Galactose oxidase, central domain - - - 0.0000000000004144 71.0
TLS3_k127_7189406_0 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009892 462.0
TLS3_k127_7189406_1 Domain of unknown function (DUF3526) K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 387.0
TLS3_k127_7189406_2 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 295.0
TLS3_k127_7189406_3 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005123 287.0
TLS3_k127_7189406_4 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001012 266.0
TLS3_k127_7189406_5 Lysine exporter protein (Lyse ygga) K11250 - - 0.000000000000000000000000000000000000000000000000000000000207 207.0
TLS3_k127_7189406_6 PFAM DGPFAETKE family protein - - - 0.000000000000000000000000000000000000000000000004187 177.0
TLS3_k127_7189406_7 SnoaL-like domain - - - 0.0000000000000000001354 95.0
TLS3_k127_7189406_8 - - - - 0.0000000003593 64.0
TLS3_k127_7203395_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 488.0
TLS3_k127_7203395_1 Sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 422.0
TLS3_k127_7203395_2 Iron-storage protein K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000001854 242.0
TLS3_k127_7203395_3 Sigma-54 interaction domain K02481,K10941 - - 0.00000000000000000000001788 106.0
TLS3_k127_7203395_4 Protein involved in outer membrane biogenesis - - - 0.00000000000000000005819 98.0
TLS3_k127_7203395_5 BFD-like 2Fe-2S binding domain-containing protein K02192 - - 0.000000000001958 69.0
TLS3_k127_7215801_0 Binding-protein-dependent transport system inner membrane component K02042 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 401.0
TLS3_k127_7215801_1 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 308.0
TLS3_k127_7215801_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000003053 225.0
TLS3_k127_7215801_3 ubiE/COQ5 methyltransferase family - - - 0.0000000001189 66.0
TLS3_k127_7216873_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 398.0
TLS3_k127_7216873_1 Domain of unknown function (DUF1993) K09983 - - 0.0000000000000000000000000000000000000000000000000000000000000001636 225.0
TLS3_k127_7216873_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00003745 46.0
TLS3_k127_7222508_0 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 574.0
TLS3_k127_7222508_1 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 402.0
TLS3_k127_7222508_2 Protein of unknown function (DUF3450) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003578 270.0
TLS3_k127_7222508_3 MotA/TolQ/ExbB proton channel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009463 242.0
TLS3_k127_7222508_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000001372 225.0
TLS3_k127_7222508_5 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000000000000000000000001294 218.0
TLS3_k127_7222508_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000002248 181.0
TLS3_k127_7222508_7 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000000000000000000000000000147 174.0
TLS3_k127_7247538_0 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 309.0
TLS3_k127_7247538_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000002472 205.0
TLS3_k127_7254082_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 1.468e-207 652.0
TLS3_k127_7254082_1 Belongs to the peptidase M17 family K01255,K01259 - 3.4.11.1,3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 375.0
TLS3_k127_7254082_2 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000189 117.0
TLS3_k127_726705_0 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 309.0
TLS3_k127_726705_1 membrane protein, TerC K05794 - - 0.0000000000000003875 80.0
TLS3_k127_7271729_0 L COG3436 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 609.0
TLS3_k127_7271729_1 IS66 Orf2 like protein K07484 - - 0.0000000000000000000000000000000000000000000001687 173.0
TLS3_k127_7271729_2 Transposase K07483 - - 0.00000000000000003541 87.0
TLS3_k127_7290227_0 single-stranded DNA 5'-3' exodeoxyribonuclease activity K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002073 274.0
TLS3_k127_7290227_1 PFAM UV-endonuclease UvdE K13281 - - 0.00000000000000000000000000003791 117.0
TLS3_k127_7290227_2 Uncharacterized protein conserved in bacteria (DUF2171) - - - 0.00000000000000000002118 93.0
TLS3_k127_7318851_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1225.0
TLS3_k127_7318851_1 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family - - - 0.0 1195.0
TLS3_k127_7318851_2 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362 - 1.7.1.15 9.768e-204 648.0
TLS3_k127_7318851_3 Uroporphyrinogen-III synthase HemD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006798 341.0
TLS3_k127_7318851_4 Transcriptional regulator PadR-like family - - - 0.000000000000000000000006579 105.0
TLS3_k127_7318851_5 general secretion pathway protein - - - 0.000002304 49.0
TLS3_k127_7329815_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 527.0
TLS3_k127_7329815_1 Cysteine methyltransferase K00567 - 2.1.1.63 0.000001791 50.0
TLS3_k127_7344663_0 gag-polyprotein putative aspartyl protease - - - 0.000000000000000000000000000000004508 140.0
TLS3_k127_7344663_1 Pilus assembly protein PilX K02673 - - 0.0004331 53.0
TLS3_k127_7358735_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 478.0
TLS3_k127_7358735_1 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000001414 169.0
TLS3_k127_7359856_0 biogenesis protein K09792 - - 0.0000000000000000000000000000000000000009895 156.0
TLS3_k127_7359856_1 Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A- site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0003533 51.0
TLS3_k127_7361389_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007312 295.0
TLS3_k127_7371936_0 Capsule assembly protein Wzi - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 374.0
TLS3_k127_7371936_1 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001659 260.0
TLS3_k127_7381323_0 Domain of unknown function (DUF3459) K00700,K01236 - 2.4.1.18,3.2.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 378.0
TLS3_k127_7381323_1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214,K02438 - 3.2.1.196,3.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008428 330.0
TLS3_k127_7387674_0 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 335.0
TLS3_k127_7387674_1 Histidine kinase K02484,K07640,K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 315.0
TLS3_k127_7387674_2 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005228 276.0
TLS3_k127_7387674_3 transcriptional regulator K07662 - - 0.0000000000000000000000000000000000000000000000000000000000000001468 229.0
TLS3_k127_7391408_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03696 - - 4.118e-208 684.0
TLS3_k127_7391408_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000001272 250.0
TLS3_k127_7391408_2 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07661 - - 0.000000000000000034 82.0
TLS3_k127_7415130_0 small GTP-binding protein K02355 - - 4.556e-279 873.0
TLS3_k127_7430706_0 Cardiolipin synthase K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 390.0
TLS3_k127_7430706_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 372.0
TLS3_k127_7430706_2 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007517 253.0
TLS3_k127_7430706_3 Nudix hydrolase K01515 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019144,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0047631,GO:0050896 3.6.1.13 0.000000000000000000000000000001811 131.0
TLS3_k127_7430706_4 Belongs to the UPF0235 family K09131 - - 0.00000000000000000001468 94.0
TLS3_k127_7434677_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 539.0
TLS3_k127_7434677_1 COG0277 FAD FMN-containing dehydrogenases K00102 - 1.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 507.0
TLS3_k127_7434677_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 464.0
TLS3_k127_7434677_3 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 405.0
TLS3_k127_7434677_4 Phosphatase K07093 - - 0.00000000000000000000000008825 108.0
TLS3_k127_7434677_5 Belongs to the ompA family - - - 0.0000000000000000000001808 108.0
TLS3_k127_7434677_7 - - - - 0.000000000421 66.0
TLS3_k127_7455546_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 553.0
TLS3_k127_7455546_1 SMP-30 Gluconolaconase LRE-like K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000001827 254.0
TLS3_k127_7460841_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 477.0
TLS3_k127_7460841_1 MazG family K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 311.0
TLS3_k127_7460841_2 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.000000000000000000000000000000000000000000004357 171.0
TLS3_k127_7461484_0 receptor - - - 0.0 1125.0
TLS3_k127_7461484_1 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 509.0
TLS3_k127_7461484_2 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 336.0
TLS3_k127_7461484_3 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 329.0
TLS3_k127_7461484_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001715 250.0
TLS3_k127_7461484_5 - - - - 0.000000002365 61.0
TLS3_k127_7492649_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 6.428e-225 707.0
TLS3_k127_7492649_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 385.0
TLS3_k127_7492649_2 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 376.0
TLS3_k127_7492649_3 Protein tyrosine kinase K08282,K11916,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009618 292.0
TLS3_k127_7492649_4 Forkhead associated domain K11894 - - 0.0000000000000000000000000000000000000000000000000000000000009474 227.0
TLS3_k127_7492649_5 SMART protein phosphatase 2C domain protein K01090 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000008429 192.0
TLS3_k127_7492649_6 glyoxalase III activity - - - 0.00000000000001108 81.0
TLS3_k127_7493216_0 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 497.0
TLS3_k127_7493216_1 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 407.0
TLS3_k127_7493216_2 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000002245 182.0
TLS3_k127_7494362_0 Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 1.411e-301 945.0
TLS3_k127_7494362_1 2-methylcitrate dehydratase K01720 - 4.2.1.79 3.305e-214 674.0
TLS3_k127_7494362_2 Cellulase (glycosyl hydrolase family 5) K19355 - 3.2.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 563.0
TLS3_k127_7494362_3 Aldo/keto reductase family K19265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 462.0
TLS3_k127_7494362_4 Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 441.0
TLS3_k127_7494362_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K10715 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000003599 254.0
TLS3_k127_7494362_6 - - - - 0.000000000000000000000000000000000000000000000001204 179.0
TLS3_k127_7494362_7 - - - - 0.000000000000000000000000000000000000000000001217 169.0
TLS3_k127_7494362_8 protein TIM barrel - - - 0.0000000000000000000000001176 123.0
TLS3_k127_7536230_0 Belongs to the ParA family K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 416.0
TLS3_k127_7536230_1 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.0000000000000000000000000000000000000000000000000000000000000000006442 238.0
TLS3_k127_7536230_2 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.000000000000000000000000000005205 123.0
TLS3_k127_7536230_3 endonuclease containing a URI domain K07461 - - 0.0000000000000000009147 94.0
TLS3_k127_754368_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1227.0
TLS3_k127_754368_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 460.0
TLS3_k127_754368_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 373.0
TLS3_k127_754368_3 Inner membrane protein involved in colicin E2 resistance K06143 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 342.0
TLS3_k127_754368_4 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004161 274.0
TLS3_k127_754368_5 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.00000000000000000000000000000000000000000000006548 174.0
TLS3_k127_7554417_0 NapC/NirT cytochrome c family, N-terminal region K02569,K03532 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 331.0
TLS3_k127_7554417_1 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008762 281.0
TLS3_k127_7554417_2 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.0000000000000000000000000000000000000000007078 163.0
TLS3_k127_7554417_3 SCO1/SenC - - - 0.0000000000000000000000000000000000009993 149.0
TLS3_k127_7558730_0 ankyrin repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 526.0
TLS3_k127_7558730_1 Belongs to the peptidase S41A family - - - 0.00000000006526 69.0
TLS3_k127_7584947_0 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 369.0
TLS3_k127_7584947_1 Domain of unknown function (DUF3291) - - - 0.00000000000000000000000000000000000000000000000000000000000000003056 228.0
TLS3_k127_7584947_2 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000000000000007075 166.0
TLS3_k127_7584947_3 Cupin domain - - - 0.000000000000000000000000000000008455 133.0
TLS3_k127_7584947_4 DnaK suppressor protein K06204 - - 0.000000000000000000000005083 105.0
TLS3_k127_7584947_5 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.0000000000001251 71.0
TLS3_k127_7590775_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 6.972e-219 689.0
TLS3_k127_7590775_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 390.0
TLS3_k127_7597965_0 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 332.0
TLS3_k127_7597965_1 Histidine kinase K07637 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001746 294.0
TLS3_k127_7597965_2 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000000104 147.0
TLS3_k127_7597965_3 Involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain K03578 - 3.6.4.13 0.0000000000000000004173 92.0
TLS3_k127_7597965_4 Peptidase propeptide and YPEB domain - - - 0.0007567 47.0
TLS3_k127_759914_0 Trehalase K01194 GO:0003674,GO:0003824,GO:0004553,GO:0004555,GO:0005975,GO:0005984,GO:0005991,GO:0005993,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009628,GO:0009987,GO:0015927,GO:0016052,GO:0016787,GO:0016798,GO:0033554,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0050896,GO:0051716,GO:0071214,GO:0071470,GO:0071474,GO:0071704,GO:0104004,GO:1901575 3.2.1.28 5.308e-254 792.0
TLS3_k127_759914_1 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 415.0
TLS3_k127_759914_10 helix_turn_helix, Lux Regulon K02479,K07684 - - 0.0000002235 62.0
TLS3_k127_759914_2 Arginase family K01476 - 3.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 389.0
TLS3_k127_759914_3 YCII-related domain - - - 0.0000000000000000000000000000000000000000000004729 169.0
TLS3_k127_759914_4 SnoaL-like domain - - - 0.000000000000000000000000000000000000000001905 162.0
TLS3_k127_759914_5 belongs to the sigma-70 factor family K03088 - - 0.00000000000000000000000000000009006 125.0
TLS3_k127_759914_6 Domain of unknown function (DUF4349) - - - 0.00000000000000000000000001442 121.0
TLS3_k127_759914_7 - - - - 0.000000000000000000000004123 113.0
TLS3_k127_759914_8 Periplasmic or secreted lipoprotein - - - 0.000000000000000009449 94.0
TLS3_k127_759914_9 COG0477 Permeases of the major facilitator superfamily - - - 0.00000001795 57.0
TLS3_k127_7616940_0 Mandelate racemase muconate lactonizing enzyme K08323 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0008927,GO:0009056,GO:0016052,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044238,GO:0046872,GO:0071704,GO:1901575 4.2.1.8 7.264e-234 728.0
TLS3_k127_7616940_1 Belongs to the glycosyl hydrolase 67 family K01235 - 3.2.1.139 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 488.0
TLS3_k127_7616940_2 Glucuronate isomerase K01812 - 5.3.1.12 0.000000000000000000000000000000000000000000000000000001495 196.0
TLS3_k127_7656350_0 PFAM Amylo-alpha-16-glucosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 520.0
TLS3_k127_7656350_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 483.0
TLS3_k127_7656350_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000004745 216.0
TLS3_k127_7656350_3 Domain of unknown function (DUF4168) - - - 0.0000186 52.0
TLS3_k127_7663275_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 3.425e-216 693.0
TLS3_k127_7663275_1 Putative nucleotidyltransferase substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 382.0
TLS3_k127_7663275_2 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 348.0
TLS3_k127_7663275_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 289.0
TLS3_k127_7663275_4 EXOIII - - - 0.0000000000000000000000000000000000000000000000000000000000000002527 235.0
TLS3_k127_7663275_5 Sigma-70, region 4 - - - 0.000000000000000000000000000000000000000000000000000000001215 204.0
TLS3_k127_7663275_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000185 202.0
TLS3_k127_7663275_7 AntiSigma factor - - - 0.0000000000000000000000000000000000000004065 158.0
TLS3_k127_7683131_0 Receptor K02014 - - 2.628e-222 713.0
TLS3_k127_7683131_1 Domain of unknown function (DUF4880) K07165 - - 0.00000000001597 66.0
TLS3_k127_7685313_0 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 402.0
TLS3_k127_7685313_1 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity - - - 0.0000000000000000000000000000000000000000000000000000000000001216 219.0
TLS3_k127_7685313_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000001203 65.0
TLS3_k127_768714_0 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 429.0
TLS3_k127_768714_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004143 278.0
TLS3_k127_768714_2 - - - - 0.00000000000000000000000000000000000000000000000000000002102 211.0
TLS3_k127_768714_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000001392 154.0
TLS3_k127_768714_4 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000006239 109.0
TLS3_k127_7692425_0 Secretin N-terminal domain K12282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006593 456.0
TLS3_k127_7692425_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 331.0
TLS3_k127_7692425_2 Pilus assembly protein K12279 - - 0.00000000000000000000000000000000000000000009127 173.0
TLS3_k127_7692425_3 Type II secretion system (T2SS), protein M K12280 - - 0.00000000000000000000003277 109.0
TLS3_k127_7692425_4 PFAM Fimbrial assembly family protein - - - 0.0000000000000000003501 96.0
TLS3_k127_7692425_5 - K12281 - - 0.0000000008182 64.0
TLS3_k127_7692911_0 Transcriptional regulator K13572 - - 0.000000000000000000000000000000000000000000000000000000000001988 221.0
TLS3_k127_7692911_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.00007601 50.0
TLS3_k127_7703483_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 383.0
TLS3_k127_7703483_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 353.0
TLS3_k127_7703483_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 343.0
TLS3_k127_7710797_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 370.0
TLS3_k127_7710797_1 Histidine biosynthesis bifunctional protein HisB K01089 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 297.0
TLS3_k127_7710797_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000004827 233.0
TLS3_k127_7710797_3 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0033554,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0050896,GO:0051716,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000001518 232.0
TLS3_k127_7710797_4 Histidine biosynthesis bifunctional protein HisIE K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000002447 188.0
TLS3_k127_7717312_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 477.0
TLS3_k127_7717312_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 293.0
TLS3_k127_7717312_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000001166 219.0
TLS3_k127_7717312_3 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000002371 156.0
TLS3_k127_7717312_4 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0010876,GO:0016020,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0034613,GO:0042157,GO:0042277,GO:0043170,GO:0044238,GO:0044462,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0051668,GO:0070727,GO:0071704,GO:0071723,GO:0071944,GO:0072657,GO:1901564 - 0.00000000000000000000003776 108.0
TLS3_k127_7718015_0 Peptidase C39 family K13409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 479.0
TLS3_k127_7718015_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 289.0
TLS3_k127_7718015_2 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000003067 248.0
TLS3_k127_7722401_0 helicase superfamily c-terminal domain K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 362.0
TLS3_k127_7722401_1 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000483 179.0
TLS3_k127_7722401_2 SWIB/MDM2 domain K03169 - 5.99.1.2 0.0000000000000000000000000000000005805 134.0
TLS3_k127_7722401_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000003646 115.0
TLS3_k127_7736718_0 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 311.0
TLS3_k127_7736718_1 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 308.0
TLS3_k127_7736718_2 polar amino acid ABC transporter, inner membrane subunit K02029,K09971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006475 285.0
TLS3_k127_7736718_3 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000006009 268.0
TLS3_k127_7736718_4 ABC transporter permease K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000006122 229.0
TLS3_k127_7736718_5 PFAM Extracellular solute-binding protein, family 3 K02030 - - 0.0000000000000000000000000000000000000000000005641 170.0
TLS3_k127_7736718_6 gag-polyprotein putative aspartyl protease - - - 0.000000000000000000000000000000000000002519 160.0
TLS3_k127_7736718_7 PFAM aldo keto reductase - - - 0.00000000000000000002159 97.0
TLS3_k127_7754745_0 peroxidase K07223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 345.0
TLS3_k127_7754745_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 299.0
TLS3_k127_7765355_0 PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000001764 222.0
TLS3_k127_7787121_0 Enoyl-CoA hydratase K13816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009078 296.0
TLS3_k127_7787121_1 Histidine Phosphotransfer domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004479 267.0
TLS3_k127_7787121_2 Amidohydrolase K10221 - 3.1.1.57 0.000000000000000000000000000000000000000000000000005218 183.0
TLS3_k127_7802018_0 PFAM NADH Ubiquinone plastoquinone K05568 - - 9.649e-208 662.0
TLS3_k127_7802018_1 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter MnhD subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 479.0
TLS3_k127_7802018_2 Glycosyl hydrolase, family 20, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 419.0
TLS3_k127_7802018_3 Proton-conducting membrane transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 349.0
TLS3_k127_7802018_4 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.000000000000000000000003263 104.0
TLS3_k127_7802018_5 Domain related to MnhB subunit of Na+/H+ antiporter - - - 0.0000000000000002976 81.0
TLS3_k127_7819447_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000493 242.0
TLS3_k127_7824216_0 Concanavalin A-like lectin/glucanases superfamily - - - 2.818e-267 848.0
TLS3_k127_7824216_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009431 434.0
TLS3_k127_7824216_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002426 273.0
TLS3_k127_7856021_0 Major facilitator Superfamily K05939 - 2.3.1.40,6.2.1.20 8.245e-218 695.0
TLS3_k127_7856021_1 Two component signalling adaptor domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 582.0
TLS3_k127_7856021_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 439.0
TLS3_k127_7856021_3 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003928 248.0
TLS3_k127_7856021_4 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000002253 220.0
TLS3_k127_7861456_0 Heat shock 70 kDa protein K04043 - - 9.308e-320 988.0
TLS3_k127_7861456_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000821 458.0
TLS3_k127_7861456_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009285 406.0
TLS3_k127_7861456_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000002743 261.0
TLS3_k127_7861456_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000003088 150.0
TLS3_k127_7867332_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 404.0
TLS3_k127_7867332_1 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 327.0
TLS3_k127_7872536_0 Sugar (and other) transporter K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004586 354.0
TLS3_k127_7872536_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003839 251.0
TLS3_k127_7872536_2 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000001952 223.0
TLS3_k127_7872536_3 of the major facilitator superfamily K08151 - - 0.000000000000000000000000000000000000002319 148.0
TLS3_k127_7875236_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 8.941e-263 827.0
TLS3_k127_7875236_1 oxidoreductase K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 559.0
TLS3_k127_7875236_2 Carboxylesterase family - - - 0.000000000000000000000000000000000000000000000002679 184.0
TLS3_k127_7875236_3 Protein of unknown function (DUF2459) - - - 0.00000000000000000000000001941 117.0
TLS3_k127_7875236_4 OsmC-like protein - - - 0.0000000000000000003946 87.0
TLS3_k127_7875236_5 Protein of unknown function (DUF4242) - - - 0.000000249 61.0
TLS3_k127_7895185_0 Outer membrane protein beta-barrel family - - - 2.862e-316 990.0
TLS3_k127_7895185_1 Pfam:Y_phosphatase3C K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001826 298.0
TLS3_k127_7895185_2 Protein tyrosine serine phosphatase K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000001177 277.0
TLS3_k127_7902952_0 Histidine kinase - - - 1.711e-198 656.0
TLS3_k127_7902952_1 Belongs to the BI1 family K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000162 262.0
TLS3_k127_7902952_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000001597 161.0
TLS3_k127_7910112_0 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 2.062e-203 635.0
TLS3_k127_7910112_1 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 292.0
TLS3_k127_7924550_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 3.516e-202 638.0
TLS3_k127_7924550_1 PFAM Glycosyl transferase, family 2 K11936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 496.0
TLS3_k127_7924550_2 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 319.0
TLS3_k127_7924550_3 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000201 280.0
TLS3_k127_7924550_4 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000001865 201.0
TLS3_k127_7924550_5 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000001687 121.0
TLS3_k127_7924550_6 PFAM secretion protein HlyD family protein - - - 0.0000000000000000000000000004993 127.0
TLS3_k127_7924550_7 receptor K16091 - - 0.00001745 58.0
TLS3_k127_7927548_0 Transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001664 253.0
TLS3_k127_7936880_0 Methyl-accepting chemotaxis protein (MCP) signaling domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 388.0
TLS3_k127_7936880_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000001075 254.0
TLS3_k127_7936880_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000008514 185.0
TLS3_k127_7936880_3 Bacterial signalling protein N terminal repeat - - - 0.000000000000000000000000000000000000000001015 166.0
TLS3_k127_7936880_4 Response regulator receiver K02658 - - 0.000000000000000000000000000000008239 132.0
TLS3_k127_7936880_5 CheW-like domain - - - 0.00000000000000000000002008 107.0
TLS3_k127_7954444_0 Outer membrane receptor - - - 0.0 1051.0
TLS3_k127_7963256_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0 1004.0
TLS3_k127_7963256_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 516.0
TLS3_k127_7969417_0 PFAM Transglutaminase-like K22452 - 2.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 398.0
TLS3_k127_7969417_1 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000001655 153.0
TLS3_k127_7973027_0 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000002354 263.0
TLS3_k127_7973027_1 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.0000000000000000000000000009097 116.0
TLS3_k127_7973027_2 - - - - 0.00000000000007142 76.0
TLS3_k127_7973027_3 Major facilitator superfamily K08218 - - 0.0007747 43.0
TLS3_k127_7977257_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 304.0
TLS3_k127_7977257_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000003253 112.0
TLS3_k127_7977257_2 ORF located using Glimmer GeneMark Blastx COG0841 TC K03296,K18138 - - 0.000000007071 57.0
TLS3_k127_797948_0 transcription factor binding K15836 - - 0.00000000000000000000000000000000000000000000000581 187.0
TLS3_k127_8004841_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 428.0
TLS3_k127_8004841_1 - - - - 0.00000000000000000000000000000000000000000000000000000000003089 211.0
TLS3_k127_8004841_2 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000006973 177.0
TLS3_k127_8010492_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 591.0
TLS3_k127_8010492_1 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 287.0
TLS3_k127_8010492_2 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000002764 200.0
TLS3_k127_8010492_3 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000005731 104.0
TLS3_k127_8042806_0 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000001506 120.0
TLS3_k127_8042806_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0001281 53.0
TLS3_k127_8044721_0 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000003648 182.0
TLS3_k127_8044721_1 ECF sigma factor - - - 0.00000000000000000000000000000000000000000003352 168.0
TLS3_k127_8044721_2 Pentapeptide repeats (9 copies) - - - 0.000000000000000000000000000000000000000009214 164.0
TLS3_k127_8049791_0 Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 2.108e-215 679.0
TLS3_k127_8049791_1 Protein of unknown function (DUF1415) K09941 - - 0.0000000000000000000000000000000000000000000000000000000000000000005297 237.0
TLS3_k127_8055344_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000005197 254.0
TLS3_k127_8055488_0 peptidase M20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 509.0
TLS3_k127_8055488_1 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 388.0
TLS3_k127_8055488_2 Preprotein translocase subunit TatD K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 320.0
TLS3_k127_8055488_3 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000001119 208.0
TLS3_k127_8055488_4 WLM domain K07043 - - 0.0000000000000000000000000000000000000000000000006857 183.0
TLS3_k127_8055488_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000001877 105.0
TLS3_k127_8055488_6 peptidyl-tyrosine sulfation - - - 0.0003577 53.0
TLS3_k127_8070337_0 membrane protein terc K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 514.0
TLS3_k127_8070337_1 HWE histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 406.0
TLS3_k127_8101594_0 Glycosyl transferases group 1 K12994 - 2.4.1.349 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 358.0
TLS3_k127_8101594_1 Glycosyl transferase 4-like domain K12995 - 2.4.1.348 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 324.0
TLS3_k127_8101594_2 Pfam Methyltransferase - - - 0.000000000000000000000000000000000000000000005275 170.0
TLS3_k127_8111942_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 427.0
TLS3_k127_8111942_1 MarR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 333.0
TLS3_k127_8111942_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000001365 231.0
TLS3_k127_8111942_3 - - - - 0.0000001454 56.0
TLS3_k127_8113480_0 GTP-binding protein TypA K06207 - - 4.775e-294 912.0
TLS3_k127_8113480_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 469.0
TLS3_k127_8113480_2 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 417.0
TLS3_k127_8113480_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 389.0
TLS3_k127_8116592_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 391.0
TLS3_k127_8116592_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 364.0
TLS3_k127_8116592_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 308.0
TLS3_k127_8116592_3 EamA-like transporter family - - - 0.0000000000000000000000000002541 118.0
TLS3_k127_8122050_0 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 421.0
TLS3_k127_8122050_1 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 319.0
TLS3_k127_818053_0 NMT1-like family - - - 2.056e-209 657.0
TLS3_k127_818053_1 PFAM Nitrile hydratase alpha chain K01721,K20807 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004918 269.0
TLS3_k127_818053_2 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.000000000000000000000000000000000000000001726 158.0
TLS3_k127_818053_3 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.0000000000000000000000000001135 120.0
TLS3_k127_8189899_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.863e-218 695.0
TLS3_k127_8189899_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 554.0
TLS3_k127_8189899_10 - - - - 0.0000007814 57.0
TLS3_k127_8189899_11 - - - - 0.000001232 53.0
TLS3_k127_8189899_12 protein conserved in bacteria K03749 - - 0.00001512 55.0
TLS3_k127_8189899_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 503.0
TLS3_k127_8189899_3 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009413 360.0
TLS3_k127_8189899_4 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000007724 265.0
TLS3_k127_8189899_5 serine threonine protein kinase K11912,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000002437 243.0
TLS3_k127_8189899_6 COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA K06169 - - 0.0000000000000000000000000000000000000000000000000000007795 199.0
TLS3_k127_8189899_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000005298 192.0
TLS3_k127_8189899_8 Colicin v production K03558 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - 0.0000000000000000000000836 104.0
TLS3_k127_8189899_9 - - - - 0.000000006253 60.0
TLS3_k127_8212261_0 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 411.0
TLS3_k127_8212261_1 Hpt domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 421.0
TLS3_k127_8212261_2 Major Facilitator Superfamily K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 361.0
TLS3_k127_8212261_3 Chemotaxis phosphatase CheX K03409 - - 0.00000000000000000000000000000000000000001714 157.0
TLS3_k127_8212261_4 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000003692 150.0
TLS3_k127_8212261_5 Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000001649 151.0
TLS3_k127_8212261_6 endonuclease exonuclease phosphatase - - - 0.000000000000000000000000000001317 134.0
TLS3_k127_8212261_7 - - - - 0.00000000000002893 80.0
TLS3_k127_8212261_8 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000005031 76.0
TLS3_k127_8212261_9 cheY-homologous receiver domain - - - 0.00004183 56.0
TLS3_k127_8230994_0 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 523.0
TLS3_k127_8230994_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 383.0
TLS3_k127_8230994_2 glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003065 283.0
TLS3_k127_8230994_3 thiamine kinase activity - - - 0.00000000000000000000000000000006535 137.0
TLS3_k127_8230994_4 Phosphopantetheine attachment site - - - 0.000000000000000000000000004259 113.0
TLS3_k127_8230994_5 GtrA-like protein - - - 0.00000000000000004677 87.0
TLS3_k127_823392_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0 1019.0
TLS3_k127_823392_1 MatE K03327 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 494.0
TLS3_k127_823392_10 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 0.000000000000000000000000000000000001694 145.0
TLS3_k127_823392_11 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000004237 132.0
TLS3_k127_823392_2 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 504.0
TLS3_k127_823392_3 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 469.0
TLS3_k127_823392_4 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 465.0
TLS3_k127_823392_5 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 419.0
TLS3_k127_823392_6 PFAM regulatory protein LysR K11921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 377.0
TLS3_k127_823392_7 DNA polymerase III, delta subunit K02340 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 298.0
TLS3_k127_823392_8 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000006455 258.0
TLS3_k127_823392_9 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000004196 233.0
TLS3_k127_8247125_0 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 444.0
TLS3_k127_8247125_1 GcrA cell cycle regulator K13583 - - 0.0000000000000000001468 91.0
TLS3_k127_8247125_2 ABC-type branched-chain amino acid transport systems ATPase component - - - 0.0000000000003125 73.0
TLS3_k127_8247125_3 cobalamin synthesis protein - - - 0.000000000654 62.0
TLS3_k127_8247125_5 Domain of unknown function (DUF4167) - - - 0.0005502 47.0
TLS3_k127_8269188_0 Pathogenicity protein K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 627.0
TLS3_k127_8269188_1 membrane K07278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 373.0
TLS3_k127_8292168_0 Homoserine dehydrogenase, NAD binding domain - - - 2.209e-215 677.0
TLS3_k127_8292168_1 ATP-dependent helicase K03579 - 3.6.4.13 0.00000000000000000000513 92.0
TLS3_k127_8316898_0 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 337.0
TLS3_k127_8316898_1 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000003369 163.0
TLS3_k127_8317400_0 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 1.628e-296 929.0
TLS3_k127_8317400_1 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000002302 245.0
TLS3_k127_8317400_2 Pfam:HipA_N K07154 - 2.7.11.1 0.0000000904 54.0
TLS3_k127_8319534_0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02351 - - 0.00000000000000000000000000000000000000000000000000000000001639 215.0
TLS3_k127_8319534_1 COG0526 Thiol-disulfide isomerase and thioredoxins K02199 - - 0.00000000000000000000000000000000000000000000000000000001566 203.0
TLS3_k127_8319534_2 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000001929 194.0
TLS3_k127_8319534_3 Nitroreductase family - - - 0.0000000000000000000000000000000000000000009157 167.0
TLS3_k127_8319534_4 TIGRFAM Cytochrome c-type biogenesis protein CcmI K02200 - - 0.00000000000000000000000000000000000001365 162.0
TLS3_k127_8319534_5 subunit of a heme lyase K02200 - - 0.000000000000000000000000000003825 130.0
TLS3_k127_8334414_0 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 421.0
TLS3_k127_8334414_1 3'-5' exonuclease K07501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 350.0
TLS3_k127_8334414_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 341.0
TLS3_k127_8334414_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 315.0
TLS3_k127_8334414_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000001193 234.0
TLS3_k127_8334414_5 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000003196 185.0
TLS3_k127_8334414_6 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000001772 111.0
TLS3_k127_8334414_7 Domain of unknown function (DUF4845) - - - 0.000000003085 63.0
TLS3_k127_8362422_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.282e-277 867.0
TLS3_k127_8362422_1 diguanylate cyclase - - - 6.567e-256 811.0
TLS3_k127_8362422_2 Peptidase family M28 - - - 6.014e-200 636.0
TLS3_k127_8362422_3 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000000000000000001143 197.0
TLS3_k127_8367290_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1021.0
TLS3_k127_8367290_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000001425 146.0
TLS3_k127_8367290_2 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000224 134.0
TLS3_k127_8415726_0 Histidine kinase K07637,K07638,K07717 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 517.0
TLS3_k127_8415726_1 Deoxyribodipyrimidine photo-lyase-related protein K06876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 398.0
TLS3_k127_8415726_2 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 286.0
TLS3_k127_8415726_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000009635 123.0
TLS3_k127_8415726_4 Response regulator, receiver - - - 0.00000000000000000004786 96.0
TLS3_k127_8420212_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 6.424e-194 616.0
TLS3_k127_8420629_0 Cellulase N-terminal ig-like domain - - - 1.392e-241 764.0
TLS3_k127_8420629_1 Glycosyl hydrolases family 8 K15531 - 3.2.1.156 8.44e-218 684.0
TLS3_k127_8420629_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 590.0
TLS3_k127_8420629_3 RESPONSE REGULATOR receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 552.0
TLS3_k127_8420629_4 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 460.0
TLS3_k127_8420629_5 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 385.0
TLS3_k127_8420629_6 Converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 355.0
TLS3_k127_8420629_7 PFAM Ion transport K08714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 323.0
TLS3_k127_8420629_8 pyrroloquinoline quinone binding K12349 - 3.5.1.23 0.000000000000000000000009912 107.0
TLS3_k127_8422751_0 TonB-dependent Receptor Plug Domain - - - 1.131e-266 856.0
TLS3_k127_8422751_1 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 510.0
TLS3_k127_8422751_2 Protein of unknown function (DUF418) K07148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 364.0
TLS3_k127_8422751_3 Belongs to the peptidase S11 family K07262 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005033 284.0
TLS3_k127_8422751_4 Putative 2OG-Fe(II) oxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004975 268.0
TLS3_k127_842592_0 response regulator K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000001483 243.0
TLS3_k127_842592_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003097 247.0
TLS3_k127_842592_2 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.00000000000000000002988 95.0
TLS3_k127_842592_3 - - - - 0.0000002713 57.0
TLS3_k127_8450780_0 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 507.0
TLS3_k127_8450780_1 PFAM metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 402.0
TLS3_k127_8450780_2 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000006778 102.0
TLS3_k127_8459097_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 597.0
TLS3_k127_8468763_0 Glycosyl hydrolases family 32 K03332 - 3.2.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 499.0
TLS3_k127_8471546_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007175 414.0
TLS3_k127_8471546_1 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 374.0
TLS3_k127_8471546_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 336.0
TLS3_k127_8471546_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 320.0
TLS3_k127_8471546_4 photoreceptor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000001859 250.0
TLS3_k127_8471546_5 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000002002 104.0
TLS3_k127_8475486_0 Alpha-L-fucosidase K01206 - 3.2.1.51 1.533e-260 807.0
TLS3_k127_8475486_1 Di-glucose binding within endoplasmic reticulum - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 392.0
TLS3_k127_8475486_2 Transcriptional regulator - - - 0.0000000000003643 71.0
TLS3_k127_8484250_0 Secreted protein, containing von Willebrand factor (VWF) type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 312.0
TLS3_k127_8484250_1 von Willebrand factor (VWF) type A domain - - - 0.000000000000000000000002314 104.0
TLS3_k127_8484250_2 COG0811 Biopolymer transport proteins - - - 0.0000001059 57.0
TLS3_k127_8499928_0 COG0793 Periplasmic protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 519.0
TLS3_k127_8499928_1 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 426.0
TLS3_k127_8499928_2 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000006898 224.0
TLS3_k127_8499928_3 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000979 194.0
TLS3_k127_8499928_4 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000002053 132.0
TLS3_k127_8499928_5 - - - - 0.000000000000000002506 91.0
TLS3_k127_8516149_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 2.086e-202 649.0
TLS3_k127_8516149_1 SMART Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 323.0
TLS3_k127_8516149_2 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000004119 146.0
TLS3_k127_8530573_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001009 267.0
TLS3_k127_8530573_1 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000001753 213.0
TLS3_k127_8530573_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000006929 167.0
TLS3_k127_8530573_3 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000001206 115.0
TLS3_k127_8538961_0 TIGRFAM penicillin-binding protein, 1A K05366 - 2.4.1.129,3.4.16.4 6.911e-247 787.0
TLS3_k127_8538961_1 Pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 367.0
TLS3_k127_8538961_2 Pilus assembly protein PilO K02664 - - 0.00000000000000000000000000000000000000000000000000001076 196.0
TLS3_k127_8538961_3 mRNA catabolic process - - - 0.0000000000000000000000000000000000000000000000000003847 192.0
TLS3_k127_8538961_4 PFAM Fimbrial assembly K02663 - - 0.00000000000000000000000000000000000000000000003456 176.0
TLS3_k127_8538961_5 pilus assembly protein pilp K02665 - - 0.00000000000000000000000000000000000000000006414 165.0
TLS3_k127_8538961_6 type IV pilus secretin PilQ K02666 - - 0.0000000000000000007479 91.0
TLS3_k127_8538961_7 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000001991 81.0
TLS3_k127_8542283_0 serine-type endopeptidase activity K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 503.0
TLS3_k127_8545114_0 Glycerol-3-phosphate dehydrogenase K00057 GO:0003674,GO:0003824,GO:0004367,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006072,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 349.0
TLS3_k127_8545114_1 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000008136 207.0
TLS3_k127_8545114_2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000006025 149.0
TLS3_k127_8545114_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000005507 109.0
TLS3_k127_8545114_4 Rhodanese Homology Domain - - - 0.00000000000000000000004939 101.0
TLS3_k127_8554384_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 497.0
TLS3_k127_8554384_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 404.0
TLS3_k127_8554384_2 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 358.0
TLS3_k127_8554384_3 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000000000000000000002615 207.0
TLS3_k127_8561798_0 chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009282 379.0
TLS3_k127_8561798_1 helix_turn_helix isocitrate lyase regulation K02624 - - 0.000000000000000000000000000000000000000000000000000000002113 209.0
TLS3_k127_8561798_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000009552 196.0
TLS3_k127_8561798_3 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000005404 94.0
TLS3_k127_8562494_0 DnaJ C terminal domain K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009447 332.0
TLS3_k127_8562494_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000008211 216.0
TLS3_k127_8562494_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000004339 92.0
TLS3_k127_8570976_0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 536.0
TLS3_k127_8570976_1 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 398.0
TLS3_k127_8570976_2 MarR family transcriptional regulator - - - 0.000000000000000000000000000000000000000001626 161.0
TLS3_k127_8587195_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 449.0
TLS3_k127_8587195_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000008986 194.0
TLS3_k127_8587195_2 troponin C - GO:0003674,GO:0005488,GO:0005515,GO:0008092,GO:0031013 - 0.00000003111 57.0
TLS3_k127_866322_0 transferase activity, transferring glycosyl groups K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 570.0
TLS3_k127_866322_1 UDP binding domain K00066 - 1.1.1.132 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 558.0
TLS3_k127_866322_2 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 344.0
TLS3_k127_866322_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000006897 215.0
TLS3_k127_866322_4 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053 - - 0.0000000000000000000000000000000000000000000000000006962 191.0
TLS3_k127_866322_5 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.0001765 46.0
TLS3_k127_86844_0 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 420.0
TLS3_k127_86844_1 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 392.0
TLS3_k127_86844_2 arsenate reductase K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.0000000000000000000000000000000000000997 147.0
TLS3_k127_86844_3 PFAM Protein kinase domain - - - 0.000000009192 57.0
TLS3_k127_876736_0 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000003463 247.0
TLS3_k127_876736_1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000001213 73.0
TLS3_k127_876736_2 Helix-hairpin-helix motif K02237 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.000000001278 66.0
TLS3_k127_878942_0 tail specific protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 298.0
TLS3_k127_878942_1 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007746 248.0
TLS3_k127_878942_2 PFAM 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.000000000000000000000000000000000000000000000000000000000000000000006848 244.0
TLS3_k127_878942_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000001051 239.0
TLS3_k127_878942_4 Catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate K01631 - 4.1.2.21 0.00000000000000000000000000000000000000000000000000000001367 205.0
TLS3_k127_878942_5 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000001024 167.0
TLS3_k127_878942_6 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000001018 145.0
TLS3_k127_878942_8 TRANSCRIPTIONal - - - 0.0000000000000000002014 91.0
TLS3_k127_880001_0 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 386.0
TLS3_k127_880001_1 PFAM TadE family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 317.0
TLS3_k127_880001_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000111 259.0
TLS3_k127_880001_3 - - - - 0.000000000000000000000000000000000000000004451 171.0
TLS3_k127_880001_4 - - - - 0.0000000000000000000000001765 109.0
TLS3_k127_880001_5 - - - - 0.0000000000000000000001058 102.0
TLS3_k127_880001_6 - - - - 0.00000000006624 73.0
TLS3_k127_882071_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 8.352e-202 641.0
TLS3_k127_882071_1 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit K21801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 448.0
TLS3_k127_882071_2 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 422.0
TLS3_k127_882071_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009399 377.0
TLS3_k127_882071_4 amidase activity K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000412 118.0
TLS3_k127_902257_1 Glycine zipper 2TM domain - - - 0.000001867 51.0
TLS3_k127_9105_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 4.982e-252 807.0
TLS3_k127_9105_1 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 2.852e-219 692.0
TLS3_k127_9105_10 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001018 250.0
TLS3_k127_9105_11 FCD - - - 0.00000000000000000000000000000000000000000008997 170.0
TLS3_k127_9105_2 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000069 600.0
TLS3_k127_9105_3 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 522.0
TLS3_k127_9105_4 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 467.0
TLS3_k127_9105_5 Acetoacetyl-CoA synthase K01907 - 6.2.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 438.0
TLS3_k127_9105_6 Reduces the stability of FtsZ polymers in the presence of ATP K06916 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 388.0
TLS3_k127_9105_7 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 313.0
TLS3_k127_9105_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002008 287.0
TLS3_k127_9105_9 enoyl-CoA hydratase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000007239 256.0
TLS3_k127_919367_0 Sulfate permease family K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 467.0
TLS3_k127_919367_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000005733 243.0
TLS3_k127_924632_0 Binding-protein-dependent transport system inner membrane component K02050,K15552,K15554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 406.0
TLS3_k127_924632_1 Abc transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 367.0
TLS3_k127_924632_2 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000002161 217.0
TLS3_k127_924632_3 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000002004 177.0
TLS3_k127_924632_4 peptidyl-tyrosine sulfation - - - 0.0000000000000003778 85.0
TLS3_k127_92835_0 COG1505 Serine proteases of the peptidase family S9A K01322 - 3.4.21.26 1.027e-257 813.0
TLS3_k127_92835_1 peptidase K01278 - 3.4.14.5 2.702e-224 718.0
TLS3_k127_92835_2 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000006986 149.0
TLS3_k127_938611_0 phosphohydrolase - - - 0.0000000000000000001353 91.0
TLS3_k127_941820_0 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 599.0
TLS3_k127_947497_0 Dehydrogenase E1 component K00164 GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 1.924e-316 990.0
TLS3_k127_947497_1 TIGRFAM Undecaprenyl-phosphate glucose phosphotransferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 456.0
TLS3_k127_947497_2 dTDP biosynthetic process K00560,K00943 - 2.1.1.45,2.7.4.9 0.000000000000000000000000000000000000000000000000000229 207.0
TLS3_k127_947497_3 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000001217 91.0
TLS3_k127_955519_0 NMT1-like family K02051,K15553 - - 4.777e-207 653.0
TLS3_k127_955519_1 HlyD membrane-fusion protein of T1SS K12542 - - 0.000000000000000000000000000000000000000000000000000000000000000000002323 237.0
TLS3_k127_955519_2 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.000000000000000000000000000000000000000000000000000000000000000006106 237.0
TLS3_k127_955519_3 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000004238 176.0
TLS3_k127_955519_4 - - - - 0.00000000000000000000000000000000000000169 149.0
TLS3_k127_955837_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 471.0
TLS3_k127_955837_1 helix_turn_helix gluconate operon transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 409.0
TLS3_k127_955837_11 Putative zinc-finger - - - 0.0001884 47.0
TLS3_k127_955837_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003448 266.0
TLS3_k127_955837_3 LysR substrate binding domain K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000006482 230.0
TLS3_k127_955837_4 Glyoxalase-like domain K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000001195 173.0
TLS3_k127_955837_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000001316 179.0
TLS3_k127_955837_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000002785 147.0
TLS3_k127_955837_7 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000001251 122.0
TLS3_k127_955837_8 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000001072 118.0
TLS3_k127_955837_9 - - - - 0.000000000000000000009533 97.0
TLS3_k127_970458_0 Glycosyl hydrolase family 9 - - - 0.0 1047.0
TLS3_k127_970458_1 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000002796 185.0
TLS3_k127_970458_2 - - - - 0.0000000000000005472 81.0
TLS3_k127_975998_0 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 446.0
TLS3_k127_975998_1 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 310.0
TLS3_k127_975998_2 peptidase M20 - - - 0.00000000000000000000000000000442 119.0
TLS3_k127_975998_3 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 0.000000000000000000000000007894 110.0
TLS3_k127_975998_4 - - - - 0.00000000000000000000001368 109.0
TLS3_k127_980793_0 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 339.0
TLS3_k127_980793_1 - - - - 0.000000000000000006289 93.0
TLS3_k127_980793_2 protein methyltransferase activity - - - 0.0000000000008535 73.0
TLS3_k127_999381_0 Outer membrane receptor K02014 - - 7.393e-247 782.0
TLS3_k127_999381_1 E COG0620 Methionine synthase II (cobalamin-independent) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 492.0
TLS3_k127_999381_2 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 499.0
TLS3_k127_999381_3 citrate synthase K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007694 325.0
TLS3_k127_999381_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003507 267.0
TLS3_k127_999381_5 PFAM NADPH-dependent FMN reductase K19784 - - 0.0000000000000000000000000000000000000000000000000000000001965 214.0
TLS3_k127_999381_6 - - - - 0.00000000000000000000000000000000000001764 150.0
TLS3_k127_999381_7 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000002112 157.0