logo

Overview

ID MAG04050
Name TLS3_bin.28
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Anaerolineae
Order Promineifilales
Family Promineifilaceae
Genus Leptofilum
Species
Assembly information
Completeness (%) 71.65
Contamination (%) 2.38
GC content (%) 57.0
N50 (bp) 5,465
Genome size (bp) 4,530,035

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4057

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1005100_0 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 394.0
TLS3_k127_1005100_1 NAD+ diphosphatase activity K03426,K20449 - 1.3.7.1,3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005187 277.0
TLS3_k127_1005100_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000001411 194.0
TLS3_k127_1005100_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000000000000000000000000000000000000005133 157.0
TLS3_k127_1005100_4 Antidote-toxin recognition MazE, bacterial antitoxin K18829 - - 0.000000000000001376 79.0
TLS3_k127_1005100_5 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000006631 72.0
TLS3_k127_1008567_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 324.0
TLS3_k127_1008567_1 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 291.0
TLS3_k127_1008567_2 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000001746 260.0
TLS3_k127_1016701_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009797 259.0
TLS3_k127_1016701_1 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000001886 205.0
TLS3_k127_1016701_2 cytochrome C family protein - - - 0.000000001532 69.0
TLS3_k127_1029614_0 DinB family - - - 0.0000000000000000000000000000000000000000000000000004198 188.0
TLS3_k127_1029614_1 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000000000201 117.0
TLS3_k127_1029614_2 spore germination - - - 0.0000000000000000000000004827 108.0
TLS3_k127_1030510_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002065 280.0
TLS3_k127_1030510_1 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009193 276.0
TLS3_k127_1030510_2 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005998 285.0
TLS3_k127_1030510_3 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00000000000000000001041 95.0
TLS3_k127_1040512_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.574e-271 850.0
TLS3_k127_1040512_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 354.0
TLS3_k127_1040512_2 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 289.0
TLS3_k127_1040512_3 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000005926 138.0
TLS3_k127_1040512_4 - - - - 0.0000000000000000005292 96.0
TLS3_k127_1040512_5 PFAM helix-turn-helix domain protein - - - 0.000000000003263 75.0
TLS3_k127_1047992_0 Thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000001833 264.0
TLS3_k127_1047992_1 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000000000006425 138.0
TLS3_k127_1047992_2 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000018 129.0
TLS3_k127_1047992_3 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000001124 123.0
TLS3_k127_105336_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000001516 215.0
TLS3_k127_105336_1 Methyltransferase domain - - - 0.000000000000000000000003961 103.0
TLS3_k127_105528_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 4.901e-269 855.0
TLS3_k127_105528_1 Baseplate J-like protein K01218 - 3.2.1.78 0.00000003348 63.0
TLS3_k127_1061348_0 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000001708 188.0
TLS3_k127_1061348_1 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.00002915 56.0
TLS3_k127_1088841_0 histidine kinase A domain protein - - - 1.508e-198 666.0
TLS3_k127_1088841_1 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000002952 232.0
TLS3_k127_1088841_2 PFAM zinc finger, SWIM domain protein - - - 0.000000000000000000000008626 102.0
TLS3_k127_1088841_3 CAAX protease self-immunity K07052 - - 0.0000006764 55.0
TLS3_k127_1088841_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0001316 52.0
TLS3_k127_10977_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 406.0
TLS3_k127_10977_1 Domain of unknown function (DUF368) K08974 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 325.0
TLS3_k127_10977_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 299.0
TLS3_k127_10977_3 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006993 263.0
TLS3_k127_10977_4 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000007494 228.0
TLS3_k127_10977_5 PFAM SEC-C motif domain protein - - - 0.00000000000000000000002466 109.0
TLS3_k127_10977_6 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000009871 101.0
TLS3_k127_1125461_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 2.117e-222 696.0
TLS3_k127_1125461_1 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00651 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0008899,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 488.0
TLS3_k127_1137833_0 Isocitrate/isopropylmalate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 509.0
TLS3_k127_1137833_1 PFAM Methicillin resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 332.0
TLS3_k127_1137833_2 PFAM Methicillin resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 299.0
TLS3_k127_1137833_3 protein phosphatase 2C domain protein - - - 0.00000000000000000000000009841 112.0
TLS3_k127_1137833_4 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.000000000003478 74.0
TLS3_k127_114505_0 PFAM DNA mismatch repair protein MutS domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 484.0
TLS3_k127_114505_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000004085 116.0
TLS3_k127_1148361_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 328.0
TLS3_k127_1148361_1 - - - - 0.0000000000000000000000009512 111.0
TLS3_k127_1148361_2 - - - - 0.000000000000000000000001357 107.0
TLS3_k127_1148361_3 membrane - - - 0.0000000000003591 81.0
TLS3_k127_114842_0 helix_turn _helix lactose operon repressor K05499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000203 288.0
TLS3_k127_114842_1 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000001004 174.0
TLS3_k127_114842_2 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000003286 171.0
TLS3_k127_114842_3 metal-binding protein - - - 0.000000000000000000000000000000000001192 141.0
TLS3_k127_114842_5 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0007365 43.0
TLS3_k127_1159289_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 611.0
TLS3_k127_1159289_1 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000191 189.0
TLS3_k127_1159289_2 - - - - 0.000000000000002973 86.0
TLS3_k127_1173548_0 PFAM glycoside hydrolase, family 3 domain protein K05349 - 3.2.1.21 0.0 1026.0
TLS3_k127_1173548_1 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 375.0
TLS3_k127_1173548_2 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.0001006 46.0
TLS3_k127_1192549_0 Putative glutamine amidotransferase K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 600.0
TLS3_k127_1192549_1 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001791 284.0
TLS3_k127_1192549_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000000000000000000000000000000000000000000002625 183.0
TLS3_k127_1192549_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000001632 155.0
TLS3_k127_1192549_4 Histidine kinase K07651 - 2.7.13.3 0.000000000000000000000000000000000005246 154.0
TLS3_k127_1197384_0 PFAM Aldo keto reductase family K19265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 493.0
TLS3_k127_1197384_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001502 221.0
TLS3_k127_1197384_2 - - - - 0.000002293 52.0
TLS3_k127_1201001_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 301.0
TLS3_k127_1201001_1 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K13940 - 2.7.6.3,4.1.2.25 0.0000000000000000000000000000000000000000000000000003043 189.0
TLS3_k127_1201001_2 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000007143 85.0
TLS3_k127_1201001_3 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000008004 63.0
TLS3_k127_1208238_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 385.0
TLS3_k127_1208238_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 334.0
TLS3_k127_1208238_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000003539 69.0
TLS3_k127_122751_0 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00819,K00821 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 591.0
TLS3_k127_122751_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 469.0
TLS3_k127_122751_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000001958 233.0
TLS3_k127_122751_3 transcriptional regulator, SARP family - - - 0.000000000000000000000000000000000000002507 164.0
TLS3_k127_122751_4 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000002361 121.0
TLS3_k127_122751_5 transporter - - - 0.0000000001205 74.0
TLS3_k127_1228034_0 Uncharacterised ACR (DUF711) K09157 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 308.0
TLS3_k127_1228034_1 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001003 284.0
TLS3_k127_1228034_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000005156 183.0
TLS3_k127_1228034_3 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000003786 166.0
TLS3_k127_1228034_4 UbiA prenyltransferase family K03179,K17105 - 2.5.1.39,2.5.1.42 0.0000000000000000000000000000000000005153 151.0
TLS3_k127_1259659_0 serine-type aminopeptidase activity K14475 - - 0.000000000000000000000000002918 124.0
TLS3_k127_1262292_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 424.0
TLS3_k127_1262292_1 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003324 273.0
TLS3_k127_1262292_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - 0.000000000000000000000000000005165 128.0
TLS3_k127_1271865_0 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000004283 220.0
TLS3_k127_1288677_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 496.0
TLS3_k127_1288677_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007744 276.0
TLS3_k127_1288677_2 Likely ribonuclease with RNase H fold. K06959 - - 0.000000000000000004031 88.0
TLS3_k127_129367_0 conserved protein (COG2071) K09166 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 310.0
TLS3_k127_129367_1 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000004602 267.0
TLS3_k127_129367_2 methylglyoxal synthase activity K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.0000000000000000000000000000000000000000000000000000000000004991 214.0
TLS3_k127_129367_3 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000004557 186.0
TLS3_k127_130038_0 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 407.0
TLS3_k127_130038_1 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000009535 227.0
TLS3_k127_130038_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000003329 180.0
TLS3_k127_130038_3 Domain of unknown function (DUF4386) - - - 0.000000000000000000000000000000000000000000001125 175.0
TLS3_k127_130038_4 ferredoxin-NADP+ reductase activity - - - 0.00000000000000000000000000000000000000000002593 174.0
TLS3_k127_130038_5 - - - - 0.00000000000000000000003767 101.0
TLS3_k127_130038_6 Cupin - - - 0.000000000000000000000825 101.0
TLS3_k127_1311959_0 hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 537.0
TLS3_k127_1311959_1 Hydrogenase accessory protein HypB K03189,K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 302.0
TLS3_k127_1311959_2 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000000000000001434 114.0
TLS3_k127_1311959_3 AIR synthase related protein, C-terminal domain K04655 - - 0.0000000000000002786 82.0
TLS3_k127_1325130_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009584 396.0
TLS3_k127_1325130_1 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 340.0
TLS3_k127_1325130_2 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000002751 238.0
TLS3_k127_1325130_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000506 183.0
TLS3_k127_1336705_0 Aminotransferase K00812,K10907 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 508.0
TLS3_k127_1336705_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 512.0
TLS3_k127_1336705_10 phosphorelay sensor kinase activity K14978 - - 0.000000000000008929 88.0
TLS3_k127_1336705_11 GAF domain - - - 0.000000003774 70.0
TLS3_k127_1336705_12 - - - - 0.00001213 51.0
TLS3_k127_1336705_13 SMART protein phosphatase 2C domain protein - - - 0.00003142 57.0
TLS3_k127_1336705_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 328.0
TLS3_k127_1336705_3 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005521 278.0
TLS3_k127_1336705_4 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000001146 263.0
TLS3_k127_1336705_5 PFAM ATP-binding region, ATPase domain protein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001381 274.0
TLS3_k127_1336705_6 protein histidine kinase activity K01768,K11527,K18143 - 2.7.13.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000002035 211.0
TLS3_k127_1336705_7 protein histidine kinase activity K01768,K11527,K18143 - 2.7.13.3,4.6.1.1 0.0000000000000000000000000000000182 142.0
TLS3_k127_1336705_8 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.00000000000000000000000000003702 136.0
TLS3_k127_1336705_9 - - - - 0.0000000000000005399 82.0
TLS3_k127_1353145_0 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009593 362.0
TLS3_k127_1353145_1 molybdenum ion binding K07140 - - 0.00000000000000000000000000000000000000000000000000000000004374 214.0
TLS3_k127_1353145_2 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000000000000000000000008561 177.0
TLS3_k127_1353145_3 Cupin domain - - - 0.00000000000000000000000000000000003541 137.0
TLS3_k127_1353145_4 Branched-chain amino acid transport protein (AzlD) - - - 0.0000000000002228 70.0
TLS3_k127_1354722_0 udp-glucose 4-epimerase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008013 539.0
TLS3_k127_1354722_1 Belongs to the FPP GGPP synthase family K13787,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 385.0
TLS3_k127_1354722_2 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.000000000000000000000000000000000000000000000000000000000344 206.0
TLS3_k127_1354722_3 Transcriptional regulator, Crp Fnr family K21564 - - 0.00000000000000000000000000000000000000000000000000000108 200.0
TLS3_k127_1354722_4 Belongs to the binding-protein-dependent transport system permease family K10440 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.0000000000000000000000000000005811 124.0
TLS3_k127_1354722_5 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000003123 66.0
TLS3_k127_1354722_6 - - - - 0.00001059 53.0
TLS3_k127_1359865_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 408.0
TLS3_k127_1359865_1 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003401 276.0
TLS3_k127_1359865_2 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.000000000000000000002159 109.0
TLS3_k127_1367348_0 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005954 256.0
TLS3_k127_1367348_1 phosphatidylinositol kinase activity - - - 0.00000000000000000000000000000000000000000000000000007419 191.0
TLS3_k127_1367348_2 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000402 170.0
TLS3_k127_1367348_3 AAA domain K02282 - - 0.00000000000000000000000000000000000000004176 167.0
TLS3_k127_1367348_4 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains K02584 - - 0.00000000000000000000121 108.0
TLS3_k127_1367348_5 Protein of unknown function (DUF1328) - - - 0.0000000000005972 70.0
TLS3_k127_1369013_0 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 507.0
TLS3_k127_1369013_1 TIGRFAM glycosyltransferase, MGT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 306.0
TLS3_k127_1369013_2 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000001751 109.0
TLS3_k127_1378381_0 Glutamine cyclotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 292.0
TLS3_k127_1378381_1 Diphthamide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004312 265.0
TLS3_k127_1378381_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000003712 226.0
TLS3_k127_1378381_3 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000005679 244.0
TLS3_k127_138201_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 367.0
TLS3_k127_138201_1 PFAM cyclic nucleotide-binding K16922 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 383.0
TLS3_k127_138201_2 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002428 247.0
TLS3_k127_138201_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000004331 184.0
TLS3_k127_138201_4 - - - - 0.000000000000001005 82.0
TLS3_k127_1386821_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000002306 225.0
TLS3_k127_139914_0 choline dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003309 289.0
TLS3_k127_139914_1 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000000000000000006363 224.0
TLS3_k127_139914_2 TIGRFAM pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family K17950 - 4.4.1.25 0.00000000000000000000000000000000000000001507 162.0
TLS3_k127_139914_3 - - - - 0.000000000000000000000000000000000000003381 150.0
TLS3_k127_139914_4 - - - - 0.00000000000000000000000000000000002389 144.0
TLS3_k127_1401769_0 COGs COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase alpha subunit K00174 - 1.2.7.11,1.2.7.3 7.482e-216 679.0
TLS3_k127_1401769_1 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate family K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 505.0
TLS3_k127_1401769_2 transcriptional regulator domain protein - - - 0.00000000000000000000000000000000000249 147.0
TLS3_k127_1401769_3 - - - - 0.0001846 49.0
TLS3_k127_1404928_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1243.0
TLS3_k127_1404928_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 7.299e-198 625.0
TLS3_k127_1404928_10 serine-type aminopeptidase activity K14475 - - 0.00000000000000000000000007605 124.0
TLS3_k127_1404928_11 - - - - 0.000000000000000000000001064 109.0
TLS3_k127_1404928_13 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000003881 99.0
TLS3_k127_1404928_14 Cupin domain - - - 0.0000000000001013 71.0
TLS3_k127_1404928_15 phosphotransferase activity, carboxyl group as acceptor - - - 0.000004083 57.0
TLS3_k127_1404928_16 Domain of unknown function DUF11 - - - 0.0001364 55.0
TLS3_k127_1404928_2 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 357.0
TLS3_k127_1404928_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 355.0
TLS3_k127_1404928_4 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 306.0
TLS3_k127_1404928_5 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000008623 194.0
TLS3_k127_1404928_6 YjbR - - - 0.0000000000000000000000000000000000000000000005159 169.0
TLS3_k127_1404928_7 TIGRFAM conserved - - - 0.0000000000000000000000000000000000000000000007265 170.0
TLS3_k127_1404928_8 Acetyltransferase - - - 0.00000000000000000000000000000000000007598 151.0
TLS3_k127_1404928_9 SnoaL-like domain - - - 0.0000000000000000000000000000000000031 140.0
TLS3_k127_1405035_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000001986 166.0
TLS3_k127_1405035_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000003578 136.0
TLS3_k127_1405035_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000006061 96.0
TLS3_k127_1405035_3 PFAM glycosyl transferase family 39 - - - 0.00000000000003708 87.0
TLS3_k127_1406012_0 PFAM NHL repeat containing protein - - - 0.00000005313 65.0
TLS3_k127_1411798_0 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001178 272.0
TLS3_k127_1436720_0 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 332.0
TLS3_k127_1436720_1 Phosphotransferase enzyme family - - - 0.00000000000000000000000004144 113.0
TLS3_k127_1436720_2 - - - - 0.0000000000000000000000004275 108.0
TLS3_k127_1436720_3 Domain of unknown function (DUF4926) - - - 0.0000000000000000000003197 97.0
TLS3_k127_1436720_4 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000001359 94.0
TLS3_k127_1436720_5 von Willebrand factor, type A K07114 - - 0.000002332 52.0
TLS3_k127_1439630_0 Monooxygenase fad-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001725 249.0
TLS3_k127_1439630_1 SMART AAA ATPase - - - 0.00000000000000000000000000000000004765 140.0
TLS3_k127_1441175_0 SMART alpha amylase catalytic sub domain K01187 - 3.2.1.20 2.168e-268 835.0
TLS3_k127_1441175_1 Alkaline and neutral invertase - - - 2.438e-266 836.0
TLS3_k127_1441175_2 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 442.0
TLS3_k127_1441175_3 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K13668 - 2.4.1.346 0.00000000000000000000000000001569 120.0
TLS3_k127_1443664_0 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 427.0
TLS3_k127_1443664_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.000000000000000000000000000000000000000000003937 166.0
TLS3_k127_1443664_2 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.00001582 54.0
TLS3_k127_1445694_0 NB-ARC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 388.0
TLS3_k127_1450031_0 PFAM RNA binding S1 domain protein K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000007345 229.0
TLS3_k127_1450031_1 biotin acetyl-CoA-carboxylase ligase K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000001098 175.0
TLS3_k127_1456266_0 PFAM peptidase M16 domain protein K06972 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 452.0
TLS3_k127_1456266_1 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000001198 254.0
TLS3_k127_146838_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005275 269.0
TLS3_k127_146838_1 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000001739 226.0
TLS3_k127_146838_2 helix_turn_helix, Lux Regulon - - - 0.0001209 45.0
TLS3_k127_1469915_0 Histidine kinase K07646 - 2.7.13.3 8.38e-271 860.0
TLS3_k127_1469915_1 Amino acid permease - - - 6.481e-221 705.0
TLS3_k127_1469915_2 Magnesium chelatase, subunit ChlI K07391 - - 6.633e-206 653.0
TLS3_k127_1469915_3 fad dependent oxidoreductase K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 405.0
TLS3_k127_1469915_4 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006277 281.0
TLS3_k127_1469915_5 Polysaccharide biosynthesis protein - - - 0.000000000002576 69.0
TLS3_k127_1521094_0 PFAM AMP-dependent synthetase and ligase - - - 1.407e-217 685.0
TLS3_k127_1521094_1 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 483.0
TLS3_k127_1521094_2 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 316.0
TLS3_k127_1521094_3 Alpha beta hydrolase K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000005665 199.0
TLS3_k127_154277_0 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 355.0
TLS3_k127_154277_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007262 277.0
TLS3_k127_154277_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000009566 121.0
TLS3_k127_1548392_0 PQQ-like domain - - - 0.000000000000000000000000000000000004377 159.0
TLS3_k127_1548392_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000000004704 102.0
TLS3_k127_1548392_2 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000002328 65.0
TLS3_k127_1548392_3 Transglutaminase-like superfamily K22452 - 2.3.2.13 0.0003791 49.0
TLS3_k127_1553077_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 569.0
TLS3_k127_1553077_1 PFAM peptidase S1 and S6, chymotrypsin Hap K08070 - 1.3.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 302.0
TLS3_k127_1553077_2 translation release factor activity K03265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003485 271.0
TLS3_k127_1553077_3 deaminated base DNA N-glycosylase activity - - - 0.0000000000000000000000000000000000000007258 156.0
TLS3_k127_1561290_0 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 532.0
TLS3_k127_1561290_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000004359 181.0
TLS3_k127_1561290_2 Domain of unknown function (DUF4395) - - - 0.00000000001398 65.0
TLS3_k127_1561290_3 cell redox homeostasis K02199,K03671,K03672 - 1.8.1.8 0.000000001801 63.0
TLS3_k127_1568945_0 FAD linked oxidase domain protein K00103,K16653 GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576 1.1.3.8,1.1.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 541.0
TLS3_k127_1568945_1 PFAM ABC transporter related K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 514.0
TLS3_k127_1568945_10 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000232 86.0
TLS3_k127_1568945_11 - - - - 0.0000000002574 64.0
TLS3_k127_1568945_12 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000002213 61.0
TLS3_k127_1568945_2 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 391.0
TLS3_k127_1568945_3 Serine threonine protein kinase K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 360.0
TLS3_k127_1568945_4 Tryptophan halogenase K16033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 355.0
TLS3_k127_1568945_5 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 329.0
TLS3_k127_1568945_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007357 263.0
TLS3_k127_1568945_7 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000005007 211.0
TLS3_k127_1568945_8 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000001233 154.0
TLS3_k127_1568945_9 Putative ATPase subunit of terminase (gpP-like) - - - 0.00000000000000003365 87.0
TLS3_k127_157527_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 434.0
TLS3_k127_157527_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000612 203.0
TLS3_k127_1576181_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 2.599e-268 834.0
TLS3_k127_1576181_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 564.0
TLS3_k127_1576181_2 PFAM short-chain dehydrogenase reductase SDR K15314 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 546.0
TLS3_k127_1576181_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 419.0
TLS3_k127_1576181_4 - - - - 0.0000000000000000000000000000000002704 134.0
TLS3_k127_1576181_5 Protein of unknown function (DUF433) - - - 0.000000000000000000000001124 107.0
TLS3_k127_1576181_6 Periplasmic copper-binding protein (NosD) - - - 0.0000000000001453 80.0
TLS3_k127_1576181_7 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 0.000000001159 59.0
TLS3_k127_160594_0 haloacid dehalogenase-like hydrolase K01534 - 3.6.3.3,3.6.3.5 4.169e-231 740.0
TLS3_k127_160594_1 iron ion homeostasis K03322,K03709,K04758 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000168 280.0
TLS3_k127_160594_2 COGs COG3629 DNA-binding transcriptional activator of the SARP family - - - 0.0000000000000000000000000000000000000000000000002786 193.0
TLS3_k127_1606275_0 NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000002123 197.0
TLS3_k127_1606275_1 guanyl-nucleotide exchange factor activity K01387,K07114,K12287 - 3.4.24.3 0.00000000000000000000000000000103 134.0
TLS3_k127_1606275_2 - - - - 0.000000000000000000000001537 111.0
TLS3_k127_1625835_0 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 298.0
TLS3_k127_1625835_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004782 243.0
TLS3_k127_1625835_10 signal transduction histidine kinase - - - 0.000000000002068 68.0
TLS3_k127_1625835_2 - - - - 0.000000000000000000000000000000000000000000000000000000000004164 216.0
TLS3_k127_1625835_3 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000000000000000000000000000000000006324 215.0
TLS3_k127_1625835_4 Bacterial PH domain - - - 0.0000000000000000000000000000000000000008654 154.0
TLS3_k127_1625835_5 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.0000000000000000000000000000000000004632 150.0
TLS3_k127_1625835_6 Subtilase family - - - 0.00000000000000000000000000005965 120.0
TLS3_k127_1625835_7 - - - - 0.00000000000000000000002807 103.0
TLS3_k127_1625835_8 FmdB family transcriptional regulator - - - 0.0000000000000000001822 91.0
TLS3_k127_1625835_9 MazG nucleotide pyrophosphohydrolase domain - - - 0.000000000000000001891 97.0
TLS3_k127_1631435_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 368.0
TLS3_k127_1631435_1 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 306.0
TLS3_k127_1631435_2 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002205 267.0
TLS3_k127_1631435_3 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity K00950,K13940 - 2.7.6.3,4.1.2.25 0.0000000000000000000000000001273 123.0
TLS3_k127_1631435_4 - - - - 0.0000000000000004805 89.0
TLS3_k127_1631435_5 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K07589 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8 0.00000006915 55.0
TLS3_k127_1631435_6 Domain of unknown function (DUF1990) - - - 0.000499 50.0
TLS3_k127_1633661_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 555.0
TLS3_k127_1633661_1 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005478 273.0
TLS3_k127_1633661_2 PFAM PIN domain - - - 0.00000000000000000000000000000001876 128.0
TLS3_k127_1633661_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000022 96.0
TLS3_k127_1633661_4 lipopolysaccharide biosynthesis protein - - - 0.0000000005356 71.0
TLS3_k127_1633661_5 Band 7 protein K07192 - - 0.00005811 56.0
TLS3_k127_1635822_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 348.0
TLS3_k127_1635822_1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005008 272.0
TLS3_k127_1635822_3 PFAM Tetratricopeptide repeat - - - 0.00000000005307 76.0
TLS3_k127_1658770_0 PFAM ABC transporter related K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 401.0
TLS3_k127_1658770_1 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 302.0
TLS3_k127_1658770_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000001609 87.0
TLS3_k127_1659249_0 Carboxyl transferase domain - - - 2.041e-284 880.0
TLS3_k127_1659249_1 Pfam:CPSase_L_chain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 511.0
TLS3_k127_1659249_2 PFAM biotin lipoyl attachment domain-containing protein - - - 0.0000000000000000000000000000000000000000001045 164.0
TLS3_k127_1675371_0 ABC transporter substrate-binding protein PnrA-like K02058,K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 484.0
TLS3_k127_168293_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 392.0
TLS3_k127_168293_1 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 353.0
TLS3_k127_168293_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 304.0
TLS3_k127_168293_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001351 242.0
TLS3_k127_1689237_0 COGs COG1132 ABC-type multidrug transport system ATPase and permease components K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 525.0
TLS3_k127_1689237_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 381.0
TLS3_k127_1689237_2 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 336.0
TLS3_k127_1689237_3 (ABC) transporter K06147,K06148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 328.0
TLS3_k127_1689237_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000008625 184.0
TLS3_k127_1689237_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000002668 158.0
TLS3_k127_171521_0 peptidase S16 K01338,K04076,K04770,K16012,K16014 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000003461 198.0
TLS3_k127_171521_1 - - - - 0.000000000000000001001 96.0
TLS3_k127_171521_2 - K01992 - - 0.0000002443 58.0
TLS3_k127_1727334_0 Peptidase family S58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 434.0
TLS3_k127_1727334_1 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003957 261.0
TLS3_k127_1727334_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.000000002441 58.0
TLS3_k127_1727334_3 monoacylglycerol catabolic process K13704,K13705 GO:0001654,GO:0002084,GO:0003407,GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006464,GO:0006575,GO:0006629,GO:0006638,GO:0006639,GO:0006644,GO:0006650,GO:0006658,GO:0006660,GO:0006793,GO:0006796,GO:0006807,GO:0007272,GO:0007275,GO:0007399,GO:0007423,GO:0007610,GO:0007626,GO:0007628,GO:0008150,GO:0008152,GO:0008328,GO:0008344,GO:0008366,GO:0008474,GO:0009056,GO:0009057,GO:0009395,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0010842,GO:0010996,GO:0016020,GO:0016021,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0019637,GO:0030163,GO:0030425,GO:0030534,GO:0031224,GO:0031226,GO:0032281,GO:0032501,GO:0032502,GO:0032838,GO:0032839,GO:0032991,GO:0034702,GO:0034703,GO:0035601,GO:0036211,GO:0036269,GO:0036477,GO:0042157,GO:0042159,GO:0042219,GO:0042552,GO:0042995,GO:0043005,GO:0043010,GO:0043170,GO:0043235,GO:0043412,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044463,GO:0044464,GO:0046434,GO:0046461,GO:0046462,GO:0046464,GO:0046475,GO:0046486,GO:0046503,GO:0047372,GO:0048513,GO:0048592,GO:0048593,GO:0048646,GO:0048731,GO:0048856,GO:0048880,GO:0048881,GO:0048882,GO:0048884,GO:0048898,GO:0048899,GO:0048915,GO:0048916,GO:0048919,GO:0048925,GO:0050896,GO:0052651,GO:0052689,GO:0060041,GO:0060042,GO:0071704,GO:0071944,GO:0090596,GO:0090659,GO:0097447,GO:0097458,GO:0098599,GO:0098732,GO:0098734,GO:0098796,GO:0098797,GO:0098802,GO:0098878,GO:0099568,GO:0120025,GO:0120038,GO:0120111,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902495,GO:1990351 3.1.1.23 0.0008566 51.0
TLS3_k127_1730357_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 4.535e-202 634.0
TLS3_k127_1730357_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 347.0
TLS3_k127_1730357_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 308.0
TLS3_k127_1730357_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 300.0
TLS3_k127_1730357_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000002025 249.0
TLS3_k127_1730357_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000001952 225.0
TLS3_k127_1730357_6 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000004077 78.0
TLS3_k127_1730610_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 512.0
TLS3_k127_1730610_1 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 380.0
TLS3_k127_1730610_2 xanthine phosphoribosyltransferase activity K00769,K07101 - 2.4.2.22 0.000000000000000000000000000000000000000000000000000000002857 205.0
TLS3_k127_1730610_3 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000004911 156.0
TLS3_k127_1730610_4 - - - - 0.00000000000000000000000000001314 123.0
TLS3_k127_1730610_5 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.0000000000000002594 81.0
TLS3_k127_1730610_6 Bacterial sugar transferase - - - 0.00000000000000077 77.0
TLS3_k127_1730610_7 rod shape-determining protein MreD K03571 - - 0.000006756 54.0
TLS3_k127_1734887_0 Bacterial membrane protein, YfhO - - - 0.0000000000000000000000004396 118.0
TLS3_k127_1734887_1 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000001738 105.0
TLS3_k127_1734887_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000002414 60.0
TLS3_k127_1744759_0 Carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 330.0
TLS3_k127_1744759_1 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000001646 184.0
TLS3_k127_1744759_2 - - - - 0.0000000000000000000000000000000005353 144.0
TLS3_k127_1744759_3 - - - - 0.000000000000000000000000000002316 129.0
TLS3_k127_1744759_4 - - - - 0.0000000000000000000000125 108.0
TLS3_k127_1744759_5 - - - - 0.000000000000003738 83.0
TLS3_k127_1744759_6 Leucine-rich repeat (LRR) protein - - - 0.000000000003464 81.0
TLS3_k127_1744759_7 SPFH domain-Band 7 family - - - 0.000002541 61.0
TLS3_k127_1746022_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 9.612e-216 685.0
TLS3_k127_1747489_0 cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 626.0
TLS3_k127_1747489_1 COG0277 FAD FMN-containing dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 510.0
TLS3_k127_1747489_2 DsrE/DsrF-like family - - - 0.000000000000000000000000000000007978 130.0
TLS3_k127_1747489_3 Response regulator receiver - - - 0.000000000000000000001444 99.0
TLS3_k127_1747489_4 Cytochrome c K08738 - - 0.0000000000007908 73.0
TLS3_k127_1750678_0 Belongs to the PAPS reductase family. CysH subfamily K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004014 274.0
TLS3_k127_1750678_1 Uroporphyrin-III C-methyltransferase K02303,K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000007414 268.0
TLS3_k127_1750678_2 Nitrite and sulphite reductase 4Fe-4S domain K00392 - 1.8.7.1 0.00000000000000000000000000000000000000000002685 166.0
TLS3_k127_1750678_3 precorrin-2 dehydrogenase activity K02302,K02304 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000157 129.0
TLS3_k127_1750678_4 - - - - 0.000000000000000000000000127 113.0
TLS3_k127_1789575_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 379.0
TLS3_k127_1789575_1 ABC-type antimicrobial peptide transport system, ATPase component K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 309.0
TLS3_k127_1789575_2 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000001371 240.0
TLS3_k127_1789575_3 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000005176 195.0
TLS3_k127_1789955_0 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 424.0
TLS3_k127_1789955_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 323.0
TLS3_k127_1789955_2 PFAM glycine cleavage T protein (aminomethyl transferase) K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000494 205.0
TLS3_k127_1810099_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 460.0
TLS3_k127_1810099_1 PFAM ABC transporter related K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000001311 238.0
TLS3_k127_1810099_2 PFAM Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000001005 210.0
TLS3_k127_1810099_3 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000001195 212.0
TLS3_k127_1810099_4 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000000000000000000000004337 177.0
TLS3_k127_1810099_5 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000001134 152.0
TLS3_k127_1810099_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000553 124.0
TLS3_k127_1812143_0 PFAM lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001692 289.0
TLS3_k127_1812143_1 Histidinol-phosphate phosphatase family protein K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000001795 217.0
TLS3_k127_1812143_2 PFAM metallophosphoesterase - - - 0.000000000000000000000000000000000002874 147.0
TLS3_k127_1812143_3 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000146 119.0
TLS3_k127_1833410_0 Kelch repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001435 244.0
TLS3_k127_1833410_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000006135 199.0
TLS3_k127_1833410_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000142 128.0
TLS3_k127_1833410_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.00000000000000000000000000000009311 130.0
TLS3_k127_1833410_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000001299 113.0
TLS3_k127_1833410_5 EthD domain - - - 0.0000000000004363 73.0
TLS3_k127_1833410_6 zinc-ribbon domain - - - 0.00001281 55.0
TLS3_k127_1843942_0 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002545 313.0
TLS3_k127_1843942_1 HD domain - - - 0.0000000000000000000000002818 124.0
TLS3_k127_1847776_0 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002217 250.0
TLS3_k127_1847776_1 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000009494 166.0
TLS3_k127_1847776_2 Domain of unknown function (DUF2703) - - - 0.000000000000000000000000000000000000000003812 163.0
TLS3_k127_1847776_3 - - - - 0.00000000000000000000000000000003584 130.0
TLS3_k127_1847776_4 PFAM NHL repeat containing protein K13735 - - 0.00000002175 67.0
TLS3_k127_1847776_5 Cell wall-associated hydrolase (invasion-associated protein) - - - 0.000000558 61.0
TLS3_k127_1847776_6 lipolytic protein G-D-S-L family - - - 0.0006973 45.0
TLS3_k127_1853607_0 PFAM Glucose Sorbosone dehydrogenase K21430 - - 1.864e-245 769.0
TLS3_k127_1853607_1 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 609.0
TLS3_k127_1853607_2 PFAM cytoplasmic peptidoglycan synthetase domain protein K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000006126 229.0
TLS3_k127_1853607_3 Major facilitator Superfamily - - - 0.0000000000000000000000000007803 119.0
TLS3_k127_1853607_4 - - - - 0.0000000000000000004306 91.0
TLS3_k127_1854096_0 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 483.0
TLS3_k127_1854096_1 Peptidase family C25 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 362.0
TLS3_k127_1854096_2 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000007017 212.0
TLS3_k127_1854096_3 Cna B domain protein - - - 0.000000000000000000000000000000000000000319 163.0
TLS3_k127_1854096_4 ABC-type multidrug transport system ATPase component - - - 0.00007625 54.0
TLS3_k127_1862745_0 ABC transporter permease K02004 - - 0.0 1045.0
TLS3_k127_1862745_1 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 346.0
TLS3_k127_1862745_2 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 297.0
TLS3_k127_1862745_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001808 265.0
TLS3_k127_1862745_4 Histidine kinase - - - 0.000004765 50.0
TLS3_k127_1872332_0 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 351.0
TLS3_k127_1872332_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 304.0
TLS3_k127_1872332_2 PFAM glucosamine galactosamine-6-phosphate isomerase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000008434 201.0
TLS3_k127_1872332_3 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000007538 192.0
TLS3_k127_1872332_4 isoprenoid biosynthetic process K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000008288 178.0
TLS3_k127_1872332_5 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000004053 152.0
TLS3_k127_1872332_6 COG1073 Hydrolases of the alpha beta superfamily K06889,K07397 - - 0.000000000000000000000000000000000001945 142.0
TLS3_k127_1872332_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000000000004583 135.0
TLS3_k127_1872332_8 Vitamin K epoxide reductase - - - 0.0000000000000000000000000000003783 131.0
TLS3_k127_1872543_0 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 355.0
TLS3_k127_1872543_1 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000003206 151.0
TLS3_k127_1872543_2 Aldo/keto reductase family - - - 0.0000000000000000000000000002829 117.0
TLS3_k127_1872543_3 PspC domain K03973 - - 0.00000004684 57.0
TLS3_k127_1879413_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 526.0
TLS3_k127_1879413_1 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 323.0
TLS3_k127_1879413_2 Two component transcriptional regulator, winged helix family K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 287.0
TLS3_k127_1879413_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003247 271.0
TLS3_k127_1879413_4 histidine kinase HAMP region domain protein K02484,K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000006211 242.0
TLS3_k127_1897907_0 (ABC) transporter K06020 GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 4.404e-289 895.0
TLS3_k127_1897907_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 9.614e-218 691.0
TLS3_k127_1897907_2 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000000000000000000000009437 206.0
TLS3_k127_1897907_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000002608 120.0
TLS3_k127_1899441_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 474.0
TLS3_k127_1899441_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 403.0
TLS3_k127_1899441_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000001648 180.0
TLS3_k127_1899441_3 PFAM GCN5-related N-acetyltransferase K03824 - - 0.000000000000000000000000000000000000000000004544 168.0
TLS3_k127_1899441_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000003873 156.0
TLS3_k127_1899441_5 CYTH - - - 0.0000000000000000000000000000000003665 137.0
TLS3_k127_1899441_6 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000000000005486 115.0
TLS3_k127_1899441_7 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000005005 85.0
TLS3_k127_1905077_0 Belongs to the ParA family K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 366.0
TLS3_k127_1905077_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 361.0
TLS3_k127_1905077_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 338.0
TLS3_k127_1905077_3 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004264 271.0
TLS3_k127_1905077_4 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007506 249.0
TLS3_k127_1905077_5 Asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.000000000000000000000000000000000000000000000000001983 188.0
TLS3_k127_1905077_6 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.000000000000000000000000000000000000000000002802 172.0
TLS3_k127_1905077_7 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.00000000000001158 77.0
TLS3_k127_1905077_8 PIN domain - - - 0.0000000000002009 77.0
TLS3_k127_1905077_9 TIGRFAM looped-hinge helix DNA binding domain, AbrB family - - - 0.0008714 46.0
TLS3_k127_1907392_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.442e-215 676.0
TLS3_k127_1907392_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 557.0
TLS3_k127_1907392_2 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.0000000000000000000000000000000000000002443 150.0
TLS3_k127_1907656_0 PFAM Amidohydrolase 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 379.0
TLS3_k127_1907656_1 - - - - 0.000000584 62.0
TLS3_k127_1912300_0 PFAM fumarate lyase K01679 - 4.2.1.2 6.513e-223 699.0
TLS3_k127_1912300_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 325.0
TLS3_k127_1912300_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000001627 166.0
TLS3_k127_1929268_0 PFAM amine oxidase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 592.0
TLS3_k127_1929268_1 PFAM Glycosyl transferase family 2 K14597 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 355.0
TLS3_k127_1933763_0 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007073 309.0
TLS3_k127_1933763_1 Peptidase, M28 - - - 0.000000000000000000000000000000000000000000000000101 195.0
TLS3_k127_1934717_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000002581 172.0
TLS3_k127_1934717_1 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000008526 143.0
TLS3_k127_1942047_0 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.00000000000000000000557 107.0
TLS3_k127_1942047_1 Membrane - - - 0.0000000000001373 83.0
TLS3_k127_1942047_2 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.0000000000005302 79.0
TLS3_k127_1942047_3 Membrane - - - 0.00000006821 57.0
TLS3_k127_1976854_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 4.198e-318 997.0
TLS3_k127_1976854_1 Domain of unknown function (DUF309) K09763 - - 0.00000000000000000000000000000007888 128.0
TLS3_k127_1980209_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003012 233.0
TLS3_k127_1980209_1 ADP binding K16247 - - 0.00000000000000000000000000003261 130.0
TLS3_k127_1980209_2 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.0000428 51.0
TLS3_k127_1984099_0 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 330.0
TLS3_k127_1984099_1 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 312.0
TLS3_k127_1984099_2 peptidase - - - 0.00000000000003267 84.0
TLS3_k127_1986994_0 Putative glucoamylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 552.0
TLS3_k127_1986994_1 Putative glucoamylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 426.0
TLS3_k127_1986994_2 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 417.0
TLS3_k127_1998662_1 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000006258 87.0
TLS3_k127_200159_0 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 423.0
TLS3_k127_200159_1 Sulphur transport K07112 - - 0.00000000002032 64.0
TLS3_k127_2005812_0 PFAM Exonuclease, RNase T and DNA polymerase III K02342,K03722 - 2.7.7.7,3.6.4.12 9.598e-238 766.0
TLS3_k127_2005812_1 Homoserine dehydrogenase K00003,K12524 - 1.1.1.3,2.7.2.4 0.0000001912 55.0
TLS3_k127_2005812_2 Dystroglycan-type cadherin-like domains. - - - 0.0000006491 63.0
TLS3_k127_2022598_0 PFAM Bacterial regulatory proteins, luxR family K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 493.0
TLS3_k127_2022598_1 PFAM deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 331.0
TLS3_k127_2022598_2 Sigma factor PP2C-like phosphatases K01768,K07315 - 3.1.3.3,4.6.1.1 0.0000000000000000000001122 106.0
TLS3_k127_2022598_3 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0007058 43.0
TLS3_k127_2024969_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 333.0
TLS3_k127_2024969_1 PFAM Kelch motif - - - 0.0000000000000000000000000000000000000000000003673 181.0
TLS3_k127_2024969_2 Predicted membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000002647 96.0
TLS3_k127_203057_0 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 378.0
TLS3_k127_203057_1 polysaccharide catabolic process K05991 - 3.2.1.123 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 301.0
TLS3_k127_2045199_0 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 2.684e-227 717.0
TLS3_k127_2045199_1 Domain of unknown function (DUF3459) K01187 - 3.2.1.20 2.027e-197 632.0
TLS3_k127_2045199_2 Binding-protein-dependent transport system inner membrane component K10237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 467.0
TLS3_k127_2045199_3 glycerophosphodiester transmembrane transport K02026,K10238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 392.0
TLS3_k127_2045199_4 ABC-type sugar transport system, periplasmic component K02027,K10236 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 379.0
TLS3_k127_2045199_5 nucleotidyltransferase activity K07075 - - 0.0000000000000000000000000000000000000001123 155.0
TLS3_k127_2045199_6 Alpha amylase, catalytic domain K05341 - 2.4.1.4 0.00000000000000000000000000000000003274 139.0
TLS3_k127_2045199_7 nucleotidyltransferase activity - - - 0.00000000000000000000000003343 111.0
TLS3_k127_2068705_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 8.611e-250 786.0
TLS3_k127_2068705_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 345.0
TLS3_k127_2068705_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000003629 202.0
TLS3_k127_2068705_3 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000007684 179.0
TLS3_k127_2068705_4 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000002238 53.0
TLS3_k127_2071819_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 456.0
TLS3_k127_2071819_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01761 - 2.5.1.48,4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 396.0
TLS3_k127_2071819_2 Belongs to the OMP decarboxylase family. Type 2 subfamily K00762,K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.00000000000000000000000000000000000000000000000006112 187.0
TLS3_k127_2071819_3 The glycine cleavage system catalyzes the degradation of glycine K00303,K00605 - 1.5.3.1,2.1.2.10 0.00000000000000000000000000000000153 134.0
TLS3_k127_2072874_0 COG1653 ABC-type sugar transport system, periplasmic component K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 599.0
TLS3_k127_2072874_1 purine nucleotide biosynthetic process K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 345.0
TLS3_k127_2072874_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000008499 201.0
TLS3_k127_2074380_0 Carotenoid biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002463 228.0
TLS3_k127_2074380_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000001949 195.0
TLS3_k127_2074380_2 metallopeptidase activity K01183 - 3.2.1.14 0.0000000000000000000000000000000007649 145.0
TLS3_k127_2090925_0 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 589.0
TLS3_k127_2090925_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 320.0
TLS3_k127_2090925_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001272 288.0
TLS3_k127_2090925_3 extracellular matrix structural constituent - - - 0.000000000000000000000000000000000000000000000009622 182.0
TLS3_k127_2090925_4 Dodecin K09165 - - 0.000000000000000000000001114 104.0
TLS3_k127_2098967_0 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006134 367.0
TLS3_k127_2098967_1 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000004511 129.0
TLS3_k127_2098967_2 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000001146 127.0
TLS3_k127_2098967_3 aldo keto reductase - - - 0.00000000000000000000004299 102.0
TLS3_k127_2098967_5 Protein of unknown function (DUF3592) - - - 0.000000001638 65.0
TLS3_k127_2121633_0 PFAM regulatory protein, MerR K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 368.0
TLS3_k127_212516_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 530.0
TLS3_k127_212516_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05889,K12678 - 1.1.2.6 0.0000000000000000000000000000000000000000000000000002071 202.0
TLS3_k127_212516_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05889,K12678 - 1.1.2.6 0.00000000000000000000000000000000000000000001042 182.0
TLS3_k127_212516_3 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000001578 117.0
TLS3_k127_212516_4 Belongs to the glycosyl hydrolase 43 family - - - 0.000000000000000000000000000425 130.0
TLS3_k127_213154_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009147 471.0
TLS3_k127_213154_1 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009527 354.0
TLS3_k127_213154_2 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 312.0
TLS3_k127_213154_3 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000007608 130.0
TLS3_k127_213154_4 Protein of unknown function (DUF2905) - - - 0.000000000000008051 76.0
TLS3_k127_213154_5 - - - - 0.00001278 53.0
TLS3_k127_2145289_0 LPXTG-motif cell wall anchor domain - - - 5.097e-257 827.0
TLS3_k127_2145289_1 PFAM ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 375.0
TLS3_k127_2145289_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 296.0
TLS3_k127_2145289_3 Mo-co oxidoreductase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000125 225.0
TLS3_k127_2145289_4 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000007798 136.0
TLS3_k127_2145289_5 - - - - 0.000000000000000000000001123 110.0
TLS3_k127_2146333_0 ribonucleoside-diphosphate reductase activity K00525,K21636 - 1.1.98.6,1.17.4.1 1.173e-279 864.0
TLS3_k127_2146333_1 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000002265 163.0
TLS3_k127_2146333_2 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.00000000000000000000000000000000001196 145.0
TLS3_k127_2146333_3 HD domain K07814 - - 0.000007018 51.0
TLS3_k127_214734_0 Carbamoyltransferase C-terminus K00612 - - 0.00000000000000000000000000002156 117.0
TLS3_k127_214734_1 O-antigen ligase like membrane protein - - - 0.0000000000000000000000000008698 130.0
TLS3_k127_2150458_0 Transcriptional regulatory protein, C terminal K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002738 267.0
TLS3_k127_2150458_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005817 259.0
TLS3_k127_2150458_2 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000003182 244.0
TLS3_k127_2150458_3 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000006729 160.0
TLS3_k127_2150458_5 NUDIX domain - - - 0.000000003417 59.0
TLS3_k127_2155796_0 Belongs to the PEP-utilizing enzyme family K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 4.451e-241 771.0
TLS3_k127_2155796_1 Rhodanese Homology Domain K07146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 389.0
TLS3_k127_2155796_2 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 308.0
TLS3_k127_2155796_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000006925 158.0
TLS3_k127_2155796_4 - - - - 0.00001072 57.0
TLS3_k127_2157547_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008285 232.0
TLS3_k127_2157547_1 DNA binding - - - 0.000000000000000000000000000000001445 135.0
TLS3_k127_2157547_2 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000001092 120.0
TLS3_k127_2157547_3 Glycosyltransferase Family 4 K15521 - 2.4.1.250 0.00000000000000000000000000004621 118.0
TLS3_k127_2157547_4 SnoaL-like polyketide cyclase - - - 0.000001044 56.0
TLS3_k127_2158223_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.64e-208 661.0
TLS3_k127_2158223_1 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000001914 213.0
TLS3_k127_2158223_2 Major facilitator Superfamily - - - 0.00000000000000000000000006173 111.0
TLS3_k127_2158325_0 tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 518.0
TLS3_k127_2158325_1 PFAM conserved K07027 - - 0.0000001424 63.0
TLS3_k127_2167709_0 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002129 289.0
TLS3_k127_2167709_1 FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits - - - 0.0000000000000002073 88.0
TLS3_k127_2167709_2 - - - - 0.0007031 47.0
TLS3_k127_2168889_0 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000785 183.0
TLS3_k127_2168889_1 Histidine kinase K07768 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564 2.7.13.3 0.00000000000000000000000000000001327 141.0
TLS3_k127_2168889_2 Catabolite gene activator and regulatory subunit of cAMP-dependent protein K10914 - - 0.00000000000007099 83.0
TLS3_k127_2170128_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306 - 1.8.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 499.0
TLS3_k127_2170128_1 response regulator K02479 - - 0.0000000000000000000000000000000000000000000000000000000001277 211.0
TLS3_k127_2170128_2 DMSO reductase anchor subunit (DmsC) K07308 - - 0.000000000002359 74.0
TLS3_k127_2173774_0 ATP synthesis coupled electron transport K00342,K00343,K05568 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 485.0
TLS3_k127_2173774_1 NADH ubiquinone oxidoreductase, 20 Kd subunit K14088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001059 252.0
TLS3_k127_2173774_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000278 245.0
TLS3_k127_2173774_3 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa - - - 0.0000000000000000000000000000000001658 141.0
TLS3_k127_2182467_0 PFAM glycosyl transferase, family 51 - - - 4.533e-245 789.0
TLS3_k127_2184531_0 DNA methylAse - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 496.0
TLS3_k127_2184531_1 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004414 258.0
TLS3_k127_2184531_2 Glycerol-3-phosphate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002916 246.0
TLS3_k127_2184531_3 PFAM LmbE family protein K18455 - 3.5.1.115 0.00000000000000000000000000000000000000000003078 166.0
TLS3_k127_2184531_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000008462 74.0
TLS3_k127_2192227_0 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 330.0
TLS3_k127_2192227_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0004786 53.0
TLS3_k127_2196211_0 nuclear chromosome segregation - - - 7.155e-276 872.0
TLS3_k127_2196211_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000005684 95.0
TLS3_k127_2201391_0 Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 394.0
TLS3_k127_2201391_1 PFAM Enoyl-CoA hydratase isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 319.0
TLS3_k127_2201391_2 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000001961 172.0
TLS3_k127_2201391_3 ABC transporter K02003 - - 0.000000000000000000001336 99.0
TLS3_k127_2201391_4 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000176 90.0
TLS3_k127_2201391_5 hydroperoxide reductase activity - - - 0.0000000000000000002646 91.0
TLS3_k127_2201391_6 ROK family K00886 - 2.7.1.63 0.000001373 50.0
TLS3_k127_2202368_0 Zn peptidase - - - 0.0000000000000000000000000000000000000002797 169.0
TLS3_k127_2202463_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 616.0
TLS3_k127_2202463_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 363.0
TLS3_k127_2202463_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000005455 184.0
TLS3_k127_2202463_3 Histidine phosphatase superfamily (branch 1) - - - 0.000000000000000000000000000000000705 138.0
TLS3_k127_2202463_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000002756 124.0
TLS3_k127_2214392_0 response to antibiotic - - - 2.623e-209 682.0
TLS3_k127_2214392_1 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 307.0
TLS3_k127_2214392_2 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 308.0
TLS3_k127_2214392_3 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000002942 226.0
TLS3_k127_2214392_4 Domain of unknown function (DUF4332) - - - 0.000000002622 68.0
TLS3_k127_2215553_0 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000003753 216.0
TLS3_k127_2215553_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000404 140.0
TLS3_k127_2225595_0 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 1.602e-236 743.0
TLS3_k127_2225595_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 284.0
TLS3_k127_2228491_0 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000003397 169.0
TLS3_k127_2228491_1 Cold shock protein domain K03704 - - 0.00000000000000000000002731 101.0
TLS3_k127_2228491_2 Alpha beta hydrolase - - - 0.0000000000000000147 94.0
TLS3_k127_2228491_3 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000004312 79.0
TLS3_k127_2228491_4 response to heat K03668 - - 0.00000000000009157 77.0
TLS3_k127_2234867_0 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 410.0
TLS3_k127_2234867_1 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 310.0
TLS3_k127_2234867_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000002985 237.0
TLS3_k127_2234867_3 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000195 155.0
TLS3_k127_2234867_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000004665 109.0
TLS3_k127_2241528_0 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 542.0
TLS3_k127_2241528_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 481.0
TLS3_k127_2241528_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 318.0
TLS3_k127_2241528_3 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001843 269.0
TLS3_k127_2241528_4 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000001587 236.0
TLS3_k127_2241528_5 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000008104 165.0
TLS3_k127_2241528_6 Acetyltransferase (GNAT) domain K18816 - 2.3.1.82 0.000000000000000000000000001027 117.0
TLS3_k127_2241528_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000711 98.0
TLS3_k127_2241528_8 Uracil-DNA glycosylase K21929 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.000002675 49.0
TLS3_k127_2262010_0 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 504.0
TLS3_k127_2262010_1 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 486.0
TLS3_k127_2262010_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003377 275.0
TLS3_k127_2262010_3 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002706 266.0
TLS3_k127_2262010_4 Cellulose synthase K00694 - 2.4.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000002069 262.0
TLS3_k127_2262010_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003566 243.0
TLS3_k127_2262010_6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000005192 153.0
TLS3_k127_2262010_7 - - - - 0.000000000000000000000004862 117.0
TLS3_k127_2270528_0 - - - - 0.000000000000000000000000000000000000000007575 162.0
TLS3_k127_2270528_1 PFAM Tetratricopeptide repeat - - - 0.0000000003982 71.0
TLS3_k127_2270528_2 - - - - 0.0000001628 60.0
TLS3_k127_2287858_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 8.953e-206 659.0
TLS3_k127_2287858_1 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003973 283.0
TLS3_k127_2287858_2 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000007459 178.0
TLS3_k127_2287858_3 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000000000001039 110.0
TLS3_k127_2287858_4 - - - - 0.0000000006508 72.0
TLS3_k127_2287858_5 metallopeptidase activity - - - 0.000000002724 69.0
TLS3_k127_2299982_0 PFAM Aminotransferase class I and II K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 545.0
TLS3_k127_2299982_1 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 288.0
TLS3_k127_2343220_0 PFAM extracellular solute-binding protein family 1 K10117,K17315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 611.0
TLS3_k127_2343220_1 Binding-protein-dependent transport system inner membrane component K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 445.0
TLS3_k127_2343220_2 Binding-protein-dependent transport system inner membrane component K17317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 298.0
TLS3_k127_2343220_3 DNA polymerase beta domain protein region - - - 0.000000000000000000000000000000000009051 138.0
TLS3_k127_2343220_4 TIGRFAM nucleotidyltransferase substrate binding protein, HI0074 - - - 0.00000000000000000000003536 100.0
TLS3_k127_2349940_0 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 516.0
TLS3_k127_2349940_1 CAAX amino terminal protease family - - - 0.0000000000000000000000000000000005593 141.0
TLS3_k127_2349940_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K01782,K07516 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000001399 64.0
TLS3_k127_2362970_0 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000002667 183.0
TLS3_k127_2362970_1 Cyclic nucleotide-monophosphate binding domain - - - 0.00000003608 61.0
TLS3_k127_2367150_0 ABC-type dipeptide transport system, periplasmic component K02035,K12368 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006857,GO:0008150,GO:0009987,GO:0015833,GO:0020037,GO:0030288,GO:0030313,GO:0031975,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042938,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:0097159,GO:1901363 - 6.212e-221 700.0
TLS3_k127_2367150_1 PHP domain protein K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 571.0
TLS3_k127_2367150_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K12369 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 428.0
TLS3_k127_2367150_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 392.0
TLS3_k127_2367150_4 Stage II sporulation K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000381 242.0
TLS3_k127_2372786_0 PFAM aminotransferase class I and II K14267,K14287 - 2.6.1.17,2.6.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 437.0
TLS3_k127_2372786_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 311.0
TLS3_k127_2372786_2 Helix-turn-helix type 11 domain protein K13572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002014 274.0
TLS3_k127_2372786_3 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000007227 206.0
TLS3_k127_2372786_4 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000001931 195.0
TLS3_k127_2372786_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000004873 126.0
TLS3_k127_2373722_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 413.0
TLS3_k127_2373722_1 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 365.0
TLS3_k127_2373722_2 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000006055 194.0
TLS3_k127_2373722_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K00657,K07023 - 2.3.1.57 0.000000000000002445 77.0
TLS3_k127_2373722_4 - - - - 0.0002115 47.0
TLS3_k127_2379289_0 trimethylamine methyltransferase K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 604.0
TLS3_k127_2379289_1 Belongs to the GcvT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 569.0
TLS3_k127_2379289_2 FCD - - - 0.0000000000000000000000000000000000000002774 159.0
TLS3_k127_2385177_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 392.0
TLS3_k127_2385177_1 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 399.0
TLS3_k127_2385177_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000002549 83.0
TLS3_k127_2385902_0 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 561.0
TLS3_k127_2385902_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 484.0
TLS3_k127_2385902_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 317.0
TLS3_k127_2385902_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002516 276.0
TLS3_k127_2385902_4 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000001468 250.0
TLS3_k127_2385902_5 iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000000000000001435 219.0
TLS3_k127_2385902_6 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000001304 148.0
TLS3_k127_2388425_0 histidine kinase dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 416.0
TLS3_k127_2388425_1 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 355.0
TLS3_k127_2388425_10 peroxiredoxin activity K01607 - 4.1.1.44 0.00000000000000000000000001813 111.0
TLS3_k127_2388425_11 Transcriptional regulator PadR-like family - - - 0.0000000000339 65.0
TLS3_k127_2388425_12 Regulatory protein, FmdB family - - - 0.0000000008171 62.0
TLS3_k127_2388425_13 - - - - 0.00000006728 58.0
TLS3_k127_2388425_2 TIGRFAM arsenite-activated ATPase (arsA) K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 319.0
TLS3_k127_2388425_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 287.0
TLS3_k127_2388425_4 Low molecular weight phosphotyrosine protein phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008292 256.0
TLS3_k127_2388425_5 Sigma-70, region 4 type 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000122 231.0
TLS3_k127_2388425_6 PFAM formylmethanofuran dehydrogenase, subunit E region K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000002777 232.0
TLS3_k127_2388425_7 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000471 183.0
TLS3_k127_2388425_8 Chromate transporter K07240 - - 0.0000000000000000000000000000000423 126.0
TLS3_k127_2388425_9 PFAM regulatory protein, ArsR K03892 - - 0.0000000000000000000000000003962 117.0
TLS3_k127_2389654_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001304 272.0
TLS3_k127_2389654_1 Winged helix-turn helix - - - 0.0000000000000000000000000000000000000000000000000000001432 199.0
TLS3_k127_2389654_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000003464 202.0
TLS3_k127_2389654_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000001107 193.0
TLS3_k127_2389654_4 Belongs to the glycosyl hydrolase 13 family - - - 0.0000000000000000000000000002599 129.0
TLS3_k127_2389654_5 PFAM aminotransferase class V K04127 - 5.1.1.17 0.0000009973 51.0
TLS3_k127_2399629_0 Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 546.0
TLS3_k127_2399629_1 IstB-like ATP binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002427 275.0
TLS3_k127_2399629_2 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000001123 134.0
TLS3_k127_2399629_3 trisaccharide binding - - - 0.0000000001746 66.0
TLS3_k127_2399629_4 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 0.000000002655 60.0
TLS3_k127_2409195_0 peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000005646 224.0
TLS3_k127_2409195_1 PFAM regulatory protein LuxR - - - 0.00000000000000000000000000000000000000000000000000002125 192.0
TLS3_k127_2409195_2 Trypsin-like peptidase domain K08372 - - 0.00000000000000000000000000000001544 137.0
TLS3_k127_2409195_3 integral membrane protein - - - 0.00000000000000004411 89.0
TLS3_k127_2409195_4 TIR domain - - - 0.000034 54.0
TLS3_k127_2409195_5 Protein conserved in bacteria - - - 0.0001975 48.0
TLS3_k127_2414724_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 379.0
TLS3_k127_2414724_1 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000001031 224.0
TLS3_k127_2421044_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000651 237.0
TLS3_k127_2421278_0 Aldo/keto reductase family K05882 - 1.1.1.91 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 433.0
TLS3_k127_2421278_1 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 418.0
TLS3_k127_2421278_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004038 269.0
TLS3_k127_2421278_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002194 251.0
TLS3_k127_2421278_4 PFAM NC domain - - - 0.00000000000000000000000003642 111.0
TLS3_k127_2421278_5 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000002427 103.0
TLS3_k127_2421278_6 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000001874 109.0
TLS3_k127_2421782_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 3.52e-196 619.0
TLS3_k127_2421782_1 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 432.0
TLS3_k127_2421782_2 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000002354 224.0
TLS3_k127_2421782_3 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000004228 145.0
TLS3_k127_2421787_0 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007935 398.0
TLS3_k127_2421787_1 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 323.0
TLS3_k127_2421787_2 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000002835 158.0
TLS3_k127_2421787_3 - - - - 0.00000000000000000000000000000002254 128.0
TLS3_k127_2421787_4 BON domain - - - 0.000000000000008592 82.0
TLS3_k127_2427630_0 Glycosyl transferase, WecB TagA CpsF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004888 398.0
TLS3_k127_2427630_1 PFAM sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 291.0
TLS3_k127_2427630_2 Glycosyl transferase family 21 - - - 0.000000000004243 68.0
TLS3_k127_24331_0 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000002693 264.0
TLS3_k127_2439231_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 2.122e-215 687.0
TLS3_k127_2439231_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 530.0
TLS3_k127_2439231_2 PFAM ABC transporter related K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 535.0
TLS3_k127_2439231_3 Alanine dehydrogenase/PNT, C-terminal domain K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 522.0
TLS3_k127_2439231_4 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 377.0
TLS3_k127_2439231_5 NADPH quinone reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 353.0
TLS3_k127_2439231_6 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 317.0
TLS3_k127_2439231_7 Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components K05785 - - 0.0000000000000118 81.0
TLS3_k127_2439231_8 Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho- dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains K05785 GO:0001000,GO:0001073,GO:0001121,GO:0001124,GO:0003674,GO:0003676,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008494,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032270,GO:0032774,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045182,GO:0045727,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090079,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000002324 78.0
TLS3_k127_2453944_0 type II secretion system protein K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 611.0
TLS3_k127_2453944_1 KaiC K07331 - - 0.000000000000000000000000000000000000000000000000000000000001813 217.0
TLS3_k127_2453944_2 Type II secretion system (T2SS), protein F K07333 - - 0.00000000000000000000000000000000000000000000000000001008 207.0
TLS3_k127_2453944_3 aspartic-type endopeptidase activity K02654 - 3.4.23.43 0.00000006509 60.0
TLS3_k127_2453944_4 - - - - 0.0001798 53.0
TLS3_k127_2456712_0 Putative esterase K07017 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 321.0
TLS3_k127_2456712_1 SNARE-like domain protein - - - 0.0000000000000000000000006028 114.0
TLS3_k127_2456712_2 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.000000000000000000000002885 103.0
TLS3_k127_2456712_3 Domain of unknown function (DUF1992) K19373 - - 0.000000000000000005086 87.0
TLS3_k127_2462219_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 454.0
TLS3_k127_2462219_1 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005003 251.0
TLS3_k127_2462219_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate - - - 0.000000000000000000000000000000000000000000000000000000000000006472 221.0
TLS3_k127_2462219_3 Multidrug MFS transporter - - - 0.00000000000000000000000000000000000000000001354 169.0
TLS3_k127_2462219_4 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000001511 165.0
TLS3_k127_2468481_0 oxidoreductase activity K02012,K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 389.0
TLS3_k127_2468481_1 ATPase family associated with various cellular activities (AAA) K07452 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 381.0
TLS3_k127_2468481_2 PFAM Patatin K07001 - - 0.00000000000000000000000000000000000000000000000000000001069 211.0
TLS3_k127_2468481_3 PFAM Patatin K07001 - - 0.00000000000000000000000000000000019 140.0
TLS3_k127_247715_0 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 514.0
TLS3_k127_247715_1 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000000004445 141.0
TLS3_k127_247715_2 Involved in the tonB-independent uptake of proteins K03641,K20276 - - 0.0000000008987 62.0
TLS3_k127_2477424_0 PFAM ABC transporter transmembrane region - - - 9.885e-222 707.0
TLS3_k127_2477424_1 Belongs to the arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000002386 203.0
TLS3_k127_2477424_2 Bacterial SH3 domain homologues - - - 0.0000003261 59.0
TLS3_k127_2477571_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000002048 238.0
TLS3_k127_2477571_1 Domain of unknown function (DUF389) - - - 0.0000000000000000000000000000000000000000000002504 190.0
TLS3_k127_2477571_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829,K19969,K21342 - 2.7.1.71,4.2.3.152,4.2.3.154,4.2.3.4 0.000000000000000000000000000000000000000000001437 170.0
TLS3_k127_2477571_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000004404 109.0
TLS3_k127_2478514_0 PFAM alpha-L-arabinofuranosidase domain protein K01209 - 3.2.1.55 1.124e-255 794.0
TLS3_k127_2478514_1 PFAM peptidylprolyl isomerase FKBP-type K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000001884 234.0
TLS3_k127_2478514_2 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.00000000000000000000000000000000000000000000000004022 191.0
TLS3_k127_2478514_3 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000006559 181.0
TLS3_k127_2478514_4 PFAM FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000001854 166.0
TLS3_k127_2480899_0 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.00000000000000000000000000000000000000000000000000000000000000004275 235.0
TLS3_k127_2480899_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000001033 189.0
TLS3_k127_2480899_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000004446 143.0
TLS3_k127_2480899_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000009663 141.0
TLS3_k127_2480899_4 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000003918 94.0
TLS3_k127_2484443_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 325.0
TLS3_k127_2484443_1 PFAM glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008684 323.0
TLS3_k127_2484443_2 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000007283 237.0
TLS3_k127_2484443_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000416 220.0
TLS3_k127_2502944_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006515 289.0
TLS3_k127_2502944_1 sh3 domain protein K15539 - - 0.00000000000000000000000000000000000000000000000000000000000006383 229.0
TLS3_k127_2502944_2 histone H2A K63-linked ubiquitination - - - 0.0000000000000000003553 98.0
TLS3_k127_2502944_3 Protein of unknown function (DUF1232) - - - 0.000001929 56.0
TLS3_k127_2503574_0 Bacterial extracellular solute-binding protein - - - 0.0 1088.0
TLS3_k127_2503574_1 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 492.0
TLS3_k127_2503574_2 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000009813 183.0
TLS3_k127_2504111_0 Family 4 glycosyl hydrolase K01222 - 3.2.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 521.0
TLS3_k127_2504111_1 glycerophosphodiester transmembrane transport K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 353.0
TLS3_k127_2504111_2 InterPro IPR009342 IPR010383 IPR010403 K18675 - 2.4.1.280 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 329.0
TLS3_k127_2504111_3 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001127 288.0
TLS3_k127_2504111_4 Glyco_18 K01183 - 3.2.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000001138 256.0
TLS3_k127_2504187_0 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002097 284.0
TLS3_k127_2504187_1 A G-specific K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001461 261.0
TLS3_k127_2552589_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 5.509e-249 777.0
TLS3_k127_2552589_1 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 523.0
TLS3_k127_2552589_2 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 321.0
TLS3_k127_2552589_3 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000000000001479 145.0
TLS3_k127_2552589_4 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000005324 124.0
TLS3_k127_2552589_5 CoA carboxylase activity K01965,K02160 - 6.4.1.3 0.000000000000000000000000001003 119.0
TLS3_k127_2556560_0 Molecular chaperone. Has ATPase activity K04079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005825 480.0
TLS3_k127_2556560_1 dna ligase K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 301.0
TLS3_k127_2557335_0 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008111 347.0
TLS3_k127_2557335_1 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000006466 208.0
TLS3_k127_2557335_2 TIGRFAM DNA binding domain - - - 0.00000000000000000000000000000000003596 140.0
TLS3_k127_2561623_0 sodium-dependent phosphate transmembrane transporter activity K03324,K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 347.0
TLS3_k127_2561623_1 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000001778 219.0
TLS3_k127_2561623_2 AMP binding - - - 0.00000000000000000003708 100.0
TLS3_k127_2561623_3 Universal stress protein family - - - 0.00000001079 65.0
TLS3_k127_2573858_0 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 543.0
TLS3_k127_2573858_1 PFAM galactose-1-phosphate uridyl transferase domain protein K00965 GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 492.0
TLS3_k127_2573858_10 Putative membrane peptidase family (DUF2324) - - - 0.00000000000000004507 85.0
TLS3_k127_2573858_2 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 467.0
TLS3_k127_2573858_3 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 336.0
TLS3_k127_2573858_4 Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 311.0
TLS3_k127_2573858_5 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005489 281.0
TLS3_k127_2573858_6 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000116 264.0
TLS3_k127_2573858_7 - - - - 0.000000000000000000000000000001758 131.0
TLS3_k127_2573858_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000001139 122.0
TLS3_k127_2573858_9 Phospholipase_D-nuclease N-terminal - - - 0.00000000000000001564 84.0
TLS3_k127_2578316_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K05587 - 1.6.5.3 8.268e-232 729.0
TLS3_k127_2578316_1 PFAM nickel-dependent hydrogenase, large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 1.417e-211 668.0
TLS3_k127_2578316_10 hydrogenase maturation protease - - - 0.00000000000000000000006442 104.0
TLS3_k127_2578316_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K03778 - 1.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 439.0
TLS3_k127_2578316_3 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K05299,K05588 - 1.17.1.10,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 345.0
TLS3_k127_2578316_4 PFAM NADH ubiquinone oxidoreductase, 20 K18007 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000001532 236.0
TLS3_k127_2578316_5 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K05586 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000002154 224.0
TLS3_k127_2578316_6 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000003186 171.0
TLS3_k127_2578316_7 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000006324 160.0
TLS3_k127_2578316_8 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000000002832 140.0
TLS3_k127_2578316_9 - - - - 0.0000000000000000000000000000000003646 135.0
TLS3_k127_2596611_0 ABC 3 transport family K09819,K11605,K11709 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 529.0
TLS3_k127_2596611_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 475.0
TLS3_k127_2596611_2 ABC 3 transport family K11708 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004454 282.0
TLS3_k127_2596611_3 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.00000000000000000000000298 108.0
TLS3_k127_2596611_4 Peptidase C26 K01951 - 6.3.5.2 0.00000000000001405 77.0
TLS3_k127_2596611_5 Peptidase C26 K01951 - 6.3.5.2 0.00000000006846 66.0
TLS3_k127_2596611_6 Peptidase C26 K01951 - 6.3.5.2 0.00000005735 55.0
TLS3_k127_2598407_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 522.0
TLS3_k127_2598407_1 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 358.0
TLS3_k127_2598407_2 Xylose isomerase-like TIM barrel K18910 - 5.1.3.30,5.1.3.31 0.000000000000000000000000002585 114.0
TLS3_k127_2603385_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001457 271.0
TLS3_k127_2603385_1 pfam nudix - - - 0.000000000000000000000000000000000000002711 153.0
TLS3_k127_2603385_2 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000003929 108.0
TLS3_k127_2603385_3 Baseplate J-like protein K01218 - 3.2.1.78 0.000000000000000001275 99.0
TLS3_k127_2603385_4 - - - - 0.00000000000000005448 92.0
TLS3_k127_2603385_5 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000001147 61.0
TLS3_k127_2608412_0 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 408.0
TLS3_k127_2608412_1 PFAM sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 334.0
TLS3_k127_2608412_2 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000004639 232.0
TLS3_k127_2608412_3 PFAM Di-glucose binding within endoplasmic reticulum - - - 0.00000000000000000000000000000000000000000000000000000000000001617 238.0
TLS3_k127_2608412_4 lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000004839 205.0
TLS3_k127_2608412_5 - - - - 0.0000000000000000000000000000000000000000000004252 178.0
TLS3_k127_2608412_6 HsdM N-terminal domain K03427 - 2.1.1.72 0.0000000000000006372 78.0
TLS3_k127_265505_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000613 490.0
TLS3_k127_265505_1 Fic/DOC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001417 276.0
TLS3_k127_265505_2 Helicase conserved C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004498 243.0
TLS3_k127_2655199_0 SMART AAA ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 546.0
TLS3_k127_2655199_1 pyruvate kinase activity K00873,K00958 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009986,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0022607,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 434.0
TLS3_k127_2655199_2 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000002979 142.0
TLS3_k127_2655199_3 AI-2E family transporter - - - 0.0000000000001052 78.0
TLS3_k127_2684413_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 488.0
TLS3_k127_2684413_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 389.0
TLS3_k127_2684413_2 trisaccharide binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008844 368.0
TLS3_k127_2684413_3 TIGRFAM glutaredoxin-like domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006118 267.0
TLS3_k127_2685967_0 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008207 375.0
TLS3_k127_2685967_1 P22_AR N-terminal domain - - - 0.0000001697 60.0
TLS3_k127_2705588_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 571.0
TLS3_k127_2705588_1 Tetratricopeptide repeat - - - 0.00000436 52.0
TLS3_k127_2715692_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 335.0
TLS3_k127_2715692_1 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 290.0
TLS3_k127_2715692_2 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000001709 128.0
TLS3_k127_2715692_3 - - - - 0.0000000000000000000000000001474 119.0
TLS3_k127_2715692_4 Preprotein translocase SecG subunit K03075 - - 0.00000003385 57.0
TLS3_k127_2717254_0 PucR C-terminal helix-turn-helix domain K02647 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 355.0
TLS3_k127_2717254_1 Manganese containing catalase K07217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006076 315.0
TLS3_k127_2717254_2 Predicted membrane protein (DUF2243) - - - 0.000000000000000000000000114 108.0
TLS3_k127_2743519_0 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 479.0
TLS3_k127_2743519_1 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 293.0
TLS3_k127_2743519_2 Iron-containing alcohol dehydrogenase K19954 - - 0.000000000000000000000000000000000000000000000000000000000000000000001188 250.0
TLS3_k127_2743519_3 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000001785 229.0
TLS3_k127_2743519_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000004806 227.0
TLS3_k127_2743519_5 heme binding - - - 0.000000000000000000000000000000000007936 151.0
TLS3_k127_2743519_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000009235 135.0
TLS3_k127_2743519_7 self proteolysis - - - 0.00000000000000000000000003779 114.0
TLS3_k127_2743519_8 Domain of unknown function (DUF4129) - - - 0.0000000000000223 82.0
TLS3_k127_2743519_9 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000003357 66.0
TLS3_k127_2753690_0 PFAM VanW family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008714 384.0
TLS3_k127_2753690_1 PFAM phospholipase D Transphosphatidylase - - - 0.000000000000000000000000000000000000001892 153.0
TLS3_k127_2753690_2 - - - - 0.000000000000000000000000004369 112.0
TLS3_k127_2753690_3 lipolytic protein G-D-S-L family - - - 0.00000000000959 67.0
TLS3_k127_2770227_0 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 516.0
TLS3_k127_2770227_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 514.0
TLS3_k127_2770227_2 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 429.0
TLS3_k127_2770227_3 Protein of unknown function (DUF421) - - - 0.00000000000000000000000000000000000000000000008447 174.0
TLS3_k127_2770227_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000001998 85.0
TLS3_k127_2776523_0 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006247 263.0
TLS3_k127_2776523_1 WD-40 repeat - - - 0.00000000007318 72.0
TLS3_k127_2796115_0 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 492.0
TLS3_k127_2796115_1 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 331.0
TLS3_k127_2807594_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009312 567.0
TLS3_k127_2807594_1 Alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000003176 237.0
TLS3_k127_2807594_2 nUDIX hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000009247 131.0
TLS3_k127_2807594_3 Transposase - - - 0.00000000002011 68.0
TLS3_k127_2821637_0 COGs COG0491 Zn-dependent hydrolase including glyoxylase - - - 0.0000000000000000000000000000000000000000000000000001369 192.0
TLS3_k127_2821637_1 Mate efflux family protein - - - 0.000000000000000000000000000002925 128.0
TLS3_k127_2821637_2 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.000004166 59.0
TLS3_k127_2821637_3 PFAM Sporulation and spore germination - - - 0.0000421 55.0
TLS3_k127_2827748_0 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 2.082e-277 887.0
TLS3_k127_2827748_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000745 230.0
TLS3_k127_2827748_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000001944 227.0
TLS3_k127_2827748_3 PFAM single-stranded nucleic acid binding R3H domain protein - - - 0.000000000000000000000000000000000000000003714 162.0
TLS3_k127_2827748_4 Putative regulatory protein - - - 0.00000000000000000000000000000000000006367 146.0
TLS3_k127_2834119_0 xylulokinase activity K00848,K00851,K00854,K00862 - 2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5 4.579e-262 816.0
TLS3_k127_2834119_1 ABC transporter K10548 - 3.6.3.17 3.513e-257 801.0
TLS3_k127_2834119_2 L-arabinose isomerase activity K01804 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008733,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.3.1.4 1.201e-233 733.0
TLS3_k127_2834119_3 ABC-type xylose transport system, periplasmic component K02058,K10546 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 511.0
TLS3_k127_2834119_4 PFAM Branched-chain amino acid transport system permease component K10547 GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0019321,GO:0031224,GO:0042732,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0071704,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 512.0
TLS3_k127_2834119_5 Periplasmic binding protein-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 337.0
TLS3_k127_2834119_6 Class II Aldolase and Adducin N-terminal domain K03077 - 5.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001429 280.0
TLS3_k127_2834119_7 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000001026 170.0
TLS3_k127_2834119_8 Methyltransferase type 12 - - - 0.0000000000000000000000000000000009043 136.0
TLS3_k127_2848877_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 337.0
TLS3_k127_2848877_1 Intracellular protease, PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000001538 263.0
TLS3_k127_2848877_2 - - - - 0.0000000000000000000000000000000037 129.0
TLS3_k127_2848877_3 - - - - 0.00000000000002083 78.0
TLS3_k127_2870869_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005929 382.0
TLS3_k127_2870869_1 - - - - 0.0000000000000111 88.0
TLS3_k127_2870869_2 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. - - - 0.00002454 50.0
TLS3_k127_2875888_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000001157 203.0
TLS3_k127_2875888_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000588 171.0
TLS3_k127_2875888_2 Sulfatase - - - 0.000000000000000000000002444 106.0
TLS3_k127_2875888_3 Galactose-3-O-sulfotransferase - - - 0.0000007023 60.0
TLS3_k127_2875888_4 Sulfotransferase family - - - 0.0000009809 60.0
TLS3_k127_2881898_0 PFAM ABC transporter related - - - 7.308e-253 790.0
TLS3_k127_2881898_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 389.0
TLS3_k127_2881898_2 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000006433 211.0
TLS3_k127_2881898_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000009864 150.0
TLS3_k127_2881898_4 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000006991 115.0
TLS3_k127_2881898_5 NmrA-like family K00091 - 1.1.1.219 0.00000001374 62.0
TLS3_k127_29089_0 Oligopeptidase F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 531.0
TLS3_k127_29089_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 512.0
TLS3_k127_29089_2 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 429.0
TLS3_k127_29089_3 Belongs to the arginase family K01476 - 3.5.3.1 0.00000000000000000000000000000000000000000000000002064 184.0
TLS3_k127_29089_4 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000000000000000002709 171.0
TLS3_k127_2921039_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 511.0
TLS3_k127_2921039_1 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000003827 172.0
TLS3_k127_2921039_2 TIGRFAM primosome, DnaD subunit - - - 0.00000000000000000000000000000000000000000001248 168.0
TLS3_k127_2921039_3 peptidyl-tyrosine sulfation - - - 0.000002922 60.0
TLS3_k127_2927172_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.372e-255 803.0
TLS3_k127_2927172_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006246 333.0
TLS3_k127_2927172_2 DNA alkylation repair - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 335.0
TLS3_k127_2927172_3 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000001372 255.0
TLS3_k127_2927172_4 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000002779 204.0
TLS3_k127_2927172_5 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000004243 184.0
TLS3_k127_2927172_6 PFAM metallophosphoesterase - - - 0.00000000000000000000000000000009662 130.0
TLS3_k127_2927172_7 AAA domain K07028 - - 0.000000000000000000003299 107.0
TLS3_k127_2938270_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 430.0
TLS3_k127_2938270_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 327.0
TLS3_k127_2939532_0 alpha-L-arabinofuranosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 562.0
TLS3_k127_2939532_1 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 465.0
TLS3_k127_2939532_2 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 452.0
TLS3_k127_2939532_4 cellulose binding K01179 - 3.2.1.4 0.0000000005657 72.0
TLS3_k127_2939532_5 PFAM Glycosyl transferase, group 1 - - - 0.0006341 44.0
TLS3_k127_2950989_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 400.0
TLS3_k127_2950989_1 Zinc finger domain - - - 0.000000000000006712 86.0
TLS3_k127_2955842_0 metallocarboxypeptidase activity - - - 2.492e-209 664.0
TLS3_k127_2955842_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009663 295.0
TLS3_k127_2955842_2 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000003014 219.0
TLS3_k127_2965089_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000005216 231.0
TLS3_k127_2965089_1 MFS/sugar transport protein - - - 0.0000000000000000000153 93.0
TLS3_k127_2979848_0 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 419.0
TLS3_k127_2979848_1 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000001085 114.0
TLS3_k127_2986924_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 3.989e-244 768.0
TLS3_k127_2986924_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 339.0
TLS3_k127_2986924_2 PFAM single-stranded nucleic acid binding R3H domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 322.0
TLS3_k127_2986924_3 PFAM succinate dehydrogenase cytochrome b subunit K00241 - - 0.000000000000000000000146 103.0
TLS3_k127_2986924_5 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.00000000000000000003226 95.0
TLS3_k127_2986924_6 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000004569 90.0
TLS3_k127_2993191_0 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 479.0
TLS3_k127_2993191_1 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 350.0
TLS3_k127_2993191_2 PFAM peptidase M4 thermolysin - - - 0.0000000000000000003371 102.0
TLS3_k127_2993191_3 - - - - 0.0000000000001601 78.0
TLS3_k127_2993191_4 amidase activity K01448,K02395 - 3.5.1.28 0.000000001428 70.0
TLS3_k127_2993191_5 phosphorelay signal transduction system - - - 0.00000000211 66.0
TLS3_k127_2995900_0 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 498.0
TLS3_k127_2995900_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 413.0
TLS3_k127_2995900_2 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 385.0
TLS3_k127_2995900_3 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 371.0
TLS3_k127_2995900_4 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000001693 180.0
TLS3_k127_2995900_5 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000001015 124.0
TLS3_k127_2996847_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008144 370.0
TLS3_k127_2996847_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 364.0
TLS3_k127_2996847_2 inorganic phosphate transmembrane transporter activity K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 349.0
TLS3_k127_2996847_3 phosphate ion binding K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 304.0
TLS3_k127_3003839_0 thiosulfate sulfurtransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 481.0
TLS3_k127_302386_0 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 477.0
TLS3_k127_302386_1 Helix-turn-helix domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 376.0
TLS3_k127_302386_2 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000706 256.0
TLS3_k127_302386_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000003306 246.0
TLS3_k127_302386_4 Uridine phosphorylase K00757 - 2.4.2.3 0.0000000000000000000000000000000000002834 150.0
TLS3_k127_302386_5 PFAM Polysaccharide biosynthesis protein - - - 0.00000008877 64.0
TLS3_k127_3026185_0 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001451 258.0
TLS3_k127_3026185_1 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000006275 176.0
TLS3_k127_3026185_2 histidine kinase HAMP region domain protein - - - 0.000000000000000000001554 98.0
TLS3_k127_3040122_0 Peptidase dimerisation domain protein K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 388.0
TLS3_k127_3040122_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000001277 151.0
TLS3_k127_3040122_2 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.0000000000000000000003797 97.0
TLS3_k127_3056486_0 membrane - - - 0.0000000000000000000001918 98.0
TLS3_k127_3056486_1 LysM domain - - - 0.00000000000002368 83.0
TLS3_k127_3056486_2 Belongs to the glycosyl hydrolase 18 family - - - 0.00009676 55.0
TLS3_k127_3064346_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000939 511.0
TLS3_k127_3064346_1 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 437.0
TLS3_k127_3064346_2 TIGRFAM FeS assembly protein SufD K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 384.0
TLS3_k127_3065324_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 383.0
TLS3_k127_3065324_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 352.0
TLS3_k127_3065324_2 ABC transporter K02003,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 295.0
TLS3_k127_3065324_3 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000000000000000000000000000002016 233.0
TLS3_k127_3065324_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000002034 85.0
TLS3_k127_3065324_5 HlyD family secretion protein K02005,K13888 - - 0.0000000000003502 82.0
TLS3_k127_306754_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000005728 185.0
TLS3_k127_306754_1 Adenylyl- / guanylyl cyclase, catalytic domain K07216 - - 0.00000000002149 77.0
TLS3_k127_306754_2 luxR family - - - 0.0003443 44.0
TLS3_k127_3072728_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 374.0
TLS3_k127_3072728_1 Metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006841 251.0
TLS3_k127_3072728_2 amine dehydrogenase activity K01406 - 3.4.24.40 0.00000000000003301 83.0
TLS3_k127_3072728_3 Nudix hydrolase - - - 0.000000002817 64.0
TLS3_k127_309429_0 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 565.0
TLS3_k127_309429_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 390.0
TLS3_k127_309429_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004169 265.0
TLS3_k127_309429_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000002561 154.0
TLS3_k127_309429_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000605 94.0
TLS3_k127_3118674_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 309.0
TLS3_k127_3118674_1 Protein of unknown function (DUF433) - - - 0.000000000000000000000000000000000000001796 148.0
TLS3_k127_3118674_2 - - - - 0.000000003351 58.0
TLS3_k127_3118674_3 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000002014 51.0
TLS3_k127_3119469_0 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000009686 171.0
TLS3_k127_3119469_1 PFAM ComEC Rec2-related protein K02238 - - 0.000000000000000000000000000000000000001929 156.0
TLS3_k127_3119469_2 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000003473 132.0
TLS3_k127_3122961_0 3-keto-5-aminohexanoate cleavage protein K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 412.0
TLS3_k127_3122961_1 AMP-binding enzyme K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 375.0
TLS3_k127_3122961_2 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 339.0
TLS3_k127_3122961_3 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001247 274.0
TLS3_k127_3122961_4 PFAM carboxyl transferase K01969 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000003689 190.0
TLS3_k127_3123540_0 PFAM ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 507.0
TLS3_k127_3123540_1 Protein of unknown function (DUF2089) - - - 0.000000000000000000000000003175 115.0
TLS3_k127_3123540_2 - - - - 0.0000000000000000002168 97.0
TLS3_k127_3124065_0 Two component transcriptional regulator, winged helix family K07669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 316.0
TLS3_k127_3124065_1 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 324.0
TLS3_k127_3124065_2 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.0000000000000000000000000000000000346 147.0
TLS3_k127_3124065_3 PspC domain - - - 0.00003487 47.0
TLS3_k127_3128772_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 5.235e-252 796.0
TLS3_k127_3128772_1 of nitrite reductase and ring-hydroxylating K05710 - - 0.0000000000000000000000005625 107.0
TLS3_k127_3134101_0 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000004411 136.0
TLS3_k127_3134101_1 Psort location CytoplasmicMembrane, score - - - 0.00000000001259 78.0
TLS3_k127_3149706_0 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000319 243.0
TLS3_k127_3149706_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000002259 207.0
TLS3_k127_3149706_2 HAD-hyrolase-like K01560,K07025 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000002733 201.0
TLS3_k127_3157198_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 1.919e-269 868.0
TLS3_k127_3157198_1 sequence-specific DNA binding - - - 0.000000000000000000000000000000007296 130.0
TLS3_k127_3157198_2 Bacterial transcriptional activator domain - - - 0.0001563 52.0
TLS3_k127_3163723_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0 1232.0
TLS3_k127_3163723_1 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008691 243.0
TLS3_k127_3163723_2 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000000000001318 79.0
TLS3_k127_3168335_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008648 583.0
TLS3_k127_3168335_1 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004303 292.0
TLS3_k127_3168335_2 maltose binding K02027,K15770 - - 0.000000000000000000000000000000001348 144.0
TLS3_k127_3168661_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 530.0
TLS3_k127_3168661_1 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004761 290.0
TLS3_k127_3168661_2 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002356 265.0
TLS3_k127_3168661_3 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000004095 233.0
TLS3_k127_3168661_4 PFAM cell divisionFtsK SpoIIIE K03466 GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000006808 223.0
TLS3_k127_3168661_5 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000005274 204.0
TLS3_k127_3168661_6 PFAM adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000008446 191.0
TLS3_k127_3168661_7 serine-type peptidase activity K04773 - - 0.00000000000000000000000000000000000000634 156.0
TLS3_k127_3168661_8 transmembrane transport K02035,K15580 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006869,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010876,GO:0015711,GO:0015718,GO:0015721,GO:0015833,GO:0015849,GO:0015850,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750 - 0.000000000000000000000000000000000001684 158.0
TLS3_k127_3168661_9 - - - - 0.0000000000000001114 89.0
TLS3_k127_3178980_0 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 493.0
TLS3_k127_3178980_1 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 434.0
TLS3_k127_3178980_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008097 375.0
TLS3_k127_3178980_3 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000004548 211.0
TLS3_k127_3178980_4 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000002536 184.0
TLS3_k127_3178980_5 Rab subfamily of small GTPases K07874 GO:0000045,GO:0000139,GO:0000149,GO:0000407,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005783,GO:0005789,GO:0005794,GO:0005795,GO:0005801,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006888,GO:0006890,GO:0006900,GO:0006906,GO:0006914,GO:0006996,GO:0007033,GO:0007154,GO:0007165,GO:0007264,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009966,GO:0009987,GO:0010646,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0016050,GO:0016070,GO:0016192,GO:0016197,GO:0016236,GO:0016462,GO:0016482,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019220,GO:0019222,GO:0019439,GO:0022406,GO:0022411,GO:0022607,GO:0023051,GO:0023052,GO:0031090,GO:0031323,GO:0031410,GO:0031982,GO:0031984,GO:0032258,GO:0032456,GO:0032984,GO:0033036,GO:0033365,GO:0034497,GO:0034498,GO:0034613,GO:0034622,GO:0034641,GO:0034655,GO:0035493,GO:0035494,GO:0035556,GO:0042147,GO:0042175,GO:0042325,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043549,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0048193,GO:0048194,GO:0048211,GO:0048278,GO:0048284,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051338,GO:0051640,GO:0051641,GO:0051649,GO:0051716,GO:0061024,GO:0061025,GO:0061709,GO:0061912,GO:0061919,GO:0065003,GO:0065007,GO:0065009,GO:0070727,GO:0070925,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072665,GO:0080134,GO:0080135,GO:0090114,GO:0090174,GO:0090304,GO:0097708,GO:0098588,GO:0098791,GO:0098827,GO:0140056,GO:1900101,GO:1901360,GO:1901361,GO:1901575,GO:1903008,GO:1905037,GO:1905897,GO:1990261 - 0.000000000000000000000000000003472 127.0
TLS3_k127_3178980_6 - - - - 0.00000000003464 73.0
TLS3_k127_3180144_0 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 570.0
TLS3_k127_3180144_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 406.0
TLS3_k127_3180144_2 cell envelope-related transcriptional attenuator - - - 0.00000000000000000000000000000000000000000000000000000004952 209.0
TLS3_k127_3180144_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000001637 133.0
TLS3_k127_3187155_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 454.0
TLS3_k127_3187155_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 434.0
TLS3_k127_3187155_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 304.0
TLS3_k127_3187155_3 Hydroxymethylglutaryl-CoA lyase K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000008724 267.0
TLS3_k127_3187155_4 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000002047 248.0
TLS3_k127_3187155_5 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000005739 214.0
TLS3_k127_3187155_6 PFAM Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000109 177.0
TLS3_k127_3187155_7 Protein of unknown function (DUF423) - - - 0.0000000000000000000000000000000000283 138.0
TLS3_k127_3187155_8 PFAM Rhodanese-like domain - - - 0.000000000000000001127 94.0
TLS3_k127_3191102_0 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 514.0
TLS3_k127_3191102_1 heme binding K21472 - - 0.00000000000000000000000000000000000000000000000000000000009584 213.0
TLS3_k127_3191102_2 hyperosmotic response - - - 0.0000000000000000000000000000000000000000000539 164.0
TLS3_k127_3191102_3 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000007798 113.0
TLS3_k127_3192595_0 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 558.0
TLS3_k127_3192595_1 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008362 282.0
TLS3_k127_3192595_2 WD40 domain protein beta Propeller K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001589 293.0
TLS3_k127_3192595_3 heme binding - - - 0.0000000000000000000000000000000000000000000005634 181.0
TLS3_k127_3192595_4 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000002091 109.0
TLS3_k127_3192595_5 TIGRFAM channel protein, hemolysin III family K11068 - - 0.000000000000000000005958 94.0
TLS3_k127_3192595_6 Transglycosylase SLT domain - - - 0.0000002168 62.0
TLS3_k127_3200612_0 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004996 262.0
TLS3_k127_3200612_1 Transposase - - - 0.000000000000000000000000000000000000000008912 164.0
TLS3_k127_3200612_2 Transposase - - - 0.0000000000000000000003955 98.0
TLS3_k127_3200612_3 Phosphopantetheine attachment site - - - 0.0000009622 53.0
TLS3_k127_3213047_1 AraC-like ligand binding domain - - - 0.000000000004174 72.0
TLS3_k127_3216485_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 407.0
TLS3_k127_3216485_1 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001666 271.0
TLS3_k127_3216485_2 PFAM metallophosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001703 254.0
TLS3_k127_3216485_3 Inner membrane component domain - - - 0.0000000000000000000000000009764 117.0
TLS3_k127_3232140_0 diaminopimelate decarboxylase activity K01586,K05366 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.1.129,3.4.16.4,4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 372.0
TLS3_k127_3232140_1 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005688 276.0
TLS3_k127_3232140_2 phosphonoacetaldehyde hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000002326 226.0
TLS3_k127_3232140_3 protein homooligomerization - - - 0.0000002755 59.0
TLS3_k127_3232703_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000002471 119.0
TLS3_k127_3232703_1 Propeptide_C25 - - - 0.000000000000000000000000005232 128.0
TLS3_k127_3233772_0 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000001905 246.0
TLS3_k127_3233772_1 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000831 155.0
TLS3_k127_3237072_0 ABC transporter substrate-binding protein PnrA-like K02058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 545.0
TLS3_k127_3237072_1 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 444.0
TLS3_k127_3237072_2 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006336 281.0
TLS3_k127_3246772_0 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0017118,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 374.0
TLS3_k127_3246772_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000006151 196.0
TLS3_k127_3246772_2 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000929 168.0
TLS3_k127_3246772_3 Integral membrane sensor signal transduction histidine kinase - - - 0.000000000000000000000000000000694 139.0
TLS3_k127_3246772_4 heme binding - - - 0.0000000000000000000000008132 119.0
TLS3_k127_3268501_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0016625,GO:0016903,GO:0043873,GO:0050896,GO:0055114 1.2.7.1 0.0 1393.0
TLS3_k127_3268501_1 Protein of unknown function (DUF692) K09930 - - 0.000000000229 68.0
TLS3_k127_3274978_0 peptidase dimerisation domain protein K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 497.0
TLS3_k127_3274978_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 318.0
TLS3_k127_3274978_3 tungstate ion transport K01990,K07705,K10112 - - 0.0000000000000000000000000000000000000000000000000002573 197.0
TLS3_k127_3274978_4 protein homooligomerization - - - 0.0000000000000000000000000000000000000000000000000007864 190.0
TLS3_k127_3274978_5 4-vinyl reductase, 4VR - - - 0.000000000000000000000000000000000000000000001635 172.0
TLS3_k127_3274978_6 NUDIX domain - - - 0.0000000000000000000000000000000003242 136.0
TLS3_k127_3274978_7 Nucleotidyltransferase domain - - - 0.000000000000000000000000001006 115.0
TLS3_k127_3274978_8 PFAM pentapeptide repeat protein - - - 0.000000000000001132 86.0
TLS3_k127_3298637_0 response regulator, receiver K07667 - - 0.00000000001387 72.0
TLS3_k127_3298637_1 - - - - 0.00000002872 68.0
TLS3_k127_330949_0 Putative neutral zinc metallopeptidase K06973 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001691 259.0
TLS3_k127_330949_1 transferase activity, transferring acyl groups - - - 0.00000000000000000000000000000000000000000008265 167.0
TLS3_k127_330949_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000416 151.0
TLS3_k127_3320798_0 sigma-70 region 2 domain protein K03088 - - 0.00000000000000000000000000000000000000000000000000000006659 202.0
TLS3_k127_3320798_1 Nudix hydrolase - - - 0.00000000000000000000004705 104.0
TLS3_k127_3320798_3 - - - - 0.000006093 48.0
TLS3_k127_3320798_4 AntiSigma factor - - - 0.0000126 57.0
TLS3_k127_3333211_0 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002253 245.0
TLS3_k127_3333211_1 Protein of unknown function (DUF2785) - - - 0.0000000000000000000000000000000000000000000000000000000000006007 220.0
TLS3_k127_3333211_2 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000001083 197.0
TLS3_k127_3333211_3 Protein conserved in bacteria K16785 - - 0.000000000000000000000000000000000000006574 149.0
TLS3_k127_3333211_4 HD domain - - - 0.0000002924 53.0
TLS3_k127_3334445_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 4.139e-281 880.0
TLS3_k127_3334445_1 ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 298.0
TLS3_k127_3334445_2 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000000000001019 212.0
TLS3_k127_3334445_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000009061 145.0
TLS3_k127_3334445_4 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000001165 114.0
TLS3_k127_333599_0 FecCD transport family K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 414.0
TLS3_k127_333599_1 COGs COG1120 ABC-type cobalamin Fe3 -siderophores transport systems ATPase components K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 365.0
TLS3_k127_333599_2 PFAM regulatory protein, MerR K22491 - - 0.0000000000000000000002366 102.0
TLS3_k127_3336382_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 545.0
TLS3_k127_3336382_1 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 539.0
TLS3_k127_3336382_2 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299,K03281 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 525.0
TLS3_k127_3336382_3 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 457.0
TLS3_k127_3336382_4 Protein of unknown function (DUF1295) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 336.0
TLS3_k127_3336382_5 JAB1/Mov34/MPN/PAD-1 ubiquitin protease - - - 0.0000000000000000000000001271 114.0
TLS3_k127_3336382_6 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000007363 110.0
TLS3_k127_3336382_7 Prokaryotic RING finger family 1 - - - 0.00007118 52.0
TLS3_k127_3336382_8 Prokaryotic RING finger family 1 - - - 0.0001924 49.0
TLS3_k127_3341120_0 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 308.0
TLS3_k127_3341120_1 PFAM EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001154 250.0
TLS3_k127_3341120_2 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000002163 247.0
TLS3_k127_3341120_3 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000001718 215.0
TLS3_k127_3341120_4 Sulfatase - - - 0.00000000000000000000000000000000000000000000000002672 185.0
TLS3_k127_3341120_5 - - - - 0.00000000000000000000000000000000000006997 145.0
TLS3_k127_3341120_6 InterPro IPR007367 - - - 0.0000000000000000000001063 100.0
TLS3_k127_3350096_0 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 3.153e-226 707.0
TLS3_k127_3350096_1 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 582.0
TLS3_k127_3350096_2 TIGRFAM polymorphic outer membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000037 259.0
TLS3_k127_3350096_3 PFAM Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000001159 220.0
TLS3_k127_3350096_4 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000000000003545 131.0
TLS3_k127_3350096_5 - - - - 0.00000000000000000000003226 100.0
TLS3_k127_3350096_6 L,D-transpeptidase catalytic domain - - - 0.00000000006319 66.0
TLS3_k127_3350096_7 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000003307 54.0
TLS3_k127_3350096_8 Involved in the tonB-independent uptake of proteins - - - 0.000003425 60.0
TLS3_k127_3365392_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 448.0
TLS3_k127_3365392_1 Two component transcriptional regulator, winged helix family K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000003164 242.0
TLS3_k127_3365392_2 Histidine kinase-like ATPases K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000001736 250.0
TLS3_k127_3365392_3 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000001354 229.0
TLS3_k127_3365392_4 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000537 190.0
TLS3_k127_3365392_5 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.00000000000000000000000000001213 126.0
TLS3_k127_3383970_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 397.0
TLS3_k127_3383970_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 313.0
TLS3_k127_3383970_10 Ribosomal protein L36 K02919 - - 0.00000000000072 68.0
TLS3_k127_3383970_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002269 264.0
TLS3_k127_3383970_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000001055 201.0
TLS3_k127_3383970_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000005755 201.0
TLS3_k127_3383970_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000102 192.0
TLS3_k127_3383970_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000004192 184.0
TLS3_k127_3383970_7 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000005959 175.0
TLS3_k127_3383970_8 Ribosomal protein S9/S16 K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000453 136.0
TLS3_k127_3383970_9 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000001527 128.0
TLS3_k127_3387650_0 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 308.0
TLS3_k127_3387650_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000001514 174.0
TLS3_k127_3403733_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K05873,K12960 - 3.5.4.28,3.5.4.31,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 566.0
TLS3_k127_3403733_1 Pyrimidine nucleoside phosphorylase C-terminal domain K00756 - 2.4.2.2 0.000000000000000000000000004723 111.0
TLS3_k127_3403733_2 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000004508 116.0
TLS3_k127_3426366_0 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 297.0
TLS3_k127_3426366_1 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000006072 244.0
TLS3_k127_3426366_2 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000002164 165.0
TLS3_k127_3426366_3 -O-antigen K18814 - - 0.0000000000000004276 91.0
TLS3_k127_3426366_4 Conserved repeat domain - - - 0.0000000493 65.0
TLS3_k127_3439221_0 TIGRFAM geranylgeranyl reductase K10960 - 1.3.1.111,1.3.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 575.0
TLS3_k127_3439221_1 Protein of unknown function (DUF3623) - - - 0.0000000000000000000000000000000000000000000002556 179.0
TLS3_k127_3439221_2 carboxylic ester hydrolase activity - - - 0.00000000000000000000000004849 111.0
TLS3_k127_344391_0 PFAM iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 434.0
TLS3_k127_344391_1 TIGRFAM RarD protein, DMT superfamily transporter K05786 - - 0.00000000000000000000000000000000000000000000000000002553 192.0
TLS3_k127_344391_2 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000001335 190.0
TLS3_k127_344391_3 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000003758 151.0
TLS3_k127_3454466_0 COGs COG1020 Non-ribosomal peptide synthetase modules and related protein - - - 0.0 1181.0
TLS3_k127_3454466_1 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 2.927e-197 632.0
TLS3_k127_3454466_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 425.0
TLS3_k127_3454466_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000001794 236.0
TLS3_k127_3454466_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000004144 231.0
TLS3_k127_3454466_5 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000002908 183.0
TLS3_k127_3454466_6 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000003316 169.0
TLS3_k127_3454466_7 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000332 130.0
TLS3_k127_3454466_8 Belongs to the UPF0758 family K03630 - - 0.00002798 48.0
TLS3_k127_3455535_0 protein with protein kinase and helix-hairpin-helix DNA-binding domains K11130 - - 0.0000000000000000000000000000000000000000000001363 183.0
TLS3_k127_3455535_1 protein serine/threonine phosphatase activity - - - 0.0000000000006517 78.0
TLS3_k127_3459042_0 Major facilitator superfamily K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 403.0
TLS3_k127_3459042_1 Radical SAM K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 315.0
TLS3_k127_3461809_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 478.0
TLS3_k127_3461809_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 451.0
TLS3_k127_3461809_10 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000002037 86.0
TLS3_k127_3461809_11 F420H(2)-dependent quinone reductase - - - 0.000000000000000139 83.0
TLS3_k127_3461809_12 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000008412 79.0
TLS3_k127_3461809_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000005283 202.0
TLS3_k127_3461809_3 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000002086 190.0
TLS3_k127_3461809_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000009711 172.0
TLS3_k127_3461809_5 COG1520 FOG WD40-like repeat - - - 0.0000000000000000000000000000000000004785 156.0
TLS3_k127_3461809_6 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins K03217 GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869 - 0.00000000000000000000000000000004319 137.0
TLS3_k127_3461809_7 Haemolytic - - - 0.000000000000000000000000000002536 121.0
TLS3_k127_3461809_8 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000001931 113.0
TLS3_k127_3461809_9 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000354 97.0
TLS3_k127_3466240_0 Lamin Tail Domain K07004 - - 7.577e-207 668.0
TLS3_k127_3470973_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 559.0
TLS3_k127_3470973_1 Integral membrane protein DUF92 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001365 264.0
TLS3_k127_3470973_2 PFAM Protein kinase domain - - - 0.0000000000002662 72.0
TLS3_k127_3470973_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681 - 0.0000002278 55.0
TLS3_k127_3477063_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 417.0
TLS3_k127_3477063_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000005422 59.0
TLS3_k127_3477063_2 Adenylate cyclase - - - 0.0000001309 60.0
TLS3_k127_3477063_3 protein kinase activity - - - 0.00004703 54.0
TLS3_k127_348962_0 ATPase associated with various cellular activities, AAA_5 K03696 - - 0.0 1181.0
TLS3_k127_348962_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000013 289.0
TLS3_k127_348962_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000002803 269.0
TLS3_k127_348962_3 PFAM glutamine amidotransferase class-I K07010 - - 0.00000000000000000000000000000000000000000000000000000000004719 213.0
TLS3_k127_348962_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000001933 117.0
TLS3_k127_348962_5 - - - - 0.000000000000000000000005181 102.0
TLS3_k127_348962_6 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding - - - 0.000000000000003352 81.0
TLS3_k127_3496646_0 PFAM beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 316.0
TLS3_k127_3496646_1 - - - - 0.000000000000000000000000000000000000000007429 166.0
TLS3_k127_3496646_2 CAAX protease self-immunity - - - 0.000000000000000000000000005671 123.0
TLS3_k127_3496646_3 response to heat K03668,K09914 - - 0.0000000000000009799 86.0
TLS3_k127_3496646_4 - - - - 0.000000000000001596 85.0
TLS3_k127_3496646_5 CAAX protease self-immunity - - - 0.000001307 54.0
TLS3_k127_3496871_0 Predicted membrane protein (DUF2306) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001148 267.0
TLS3_k127_3496871_1 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000000000000000000000000000004922 209.0
TLS3_k127_3496871_2 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000001002 198.0
TLS3_k127_3496871_3 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000000000000003259 101.0
TLS3_k127_3496871_4 - - - - 0.000000000000006922 82.0
TLS3_k127_3498171_0 PFAM ABC transporter related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 334.0
TLS3_k127_3498171_1 carbohydrate transport K02027,K10117,K11751 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 353.0
TLS3_k127_3498171_2 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000004256 228.0
TLS3_k127_3498171_3 secretion protein HlyD family - - - 0.000000000000000000000000000000000000000000000005114 179.0
TLS3_k127_3498171_4 Two component transcriptional regulator, winged helix family K07658 - - 0.00000000000000002243 83.0
TLS3_k127_3502225_0 PIN domain K18828 - - 0.0000000000000000000000000000000000000000004106 161.0
TLS3_k127_3502225_1 Protein of unknown function DUF86 - - - 0.0000000000000000000002443 102.0
TLS3_k127_3502225_2 DNA restriction-modification system - - - 0.00000000000000005396 90.0
TLS3_k127_3502225_3 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000000504 70.0
TLS3_k127_3502225_4 PFAM DNA polymerase beta domain protein region K07076 - - 0.000004552 54.0
TLS3_k127_3502225_5 Belongs to the ParB family K03497 - - 0.0003785 53.0
TLS3_k127_3503357_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001805 273.0
TLS3_k127_3503357_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002648 251.0
TLS3_k127_3503357_2 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.0000000000000000000000000000000000002166 152.0
TLS3_k127_3503357_3 DNA topoisomerase (ATP-hydrolyzing) inhibitor activity K13652,K13653 - - 0.000000000000000000000000000001555 127.0
TLS3_k127_3503357_4 PFAM glycoside hydrolase family 39 K21000 - - 0.000000215 60.0
TLS3_k127_3505398_0 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 469.0
TLS3_k127_3505398_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 315.0
TLS3_k127_3505398_2 FGGY family of carbohydrate kinases, N-terminal domain K00848,K00879,K01813 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008993,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019200,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046835,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901575 2.7.1.5,2.7.1.51,5.3.1.14 0.0000000000000000000000000000000003697 134.0
TLS3_k127_3505398_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000003773 106.0
TLS3_k127_3520211_0 ABC transporter (Permease) K02042 - - 0.0000000000000000000000000000000000000000000000000000004394 213.0
TLS3_k127_3520211_1 organic phosphonate transmembrane transporter activity K02042 - - 0.0000000000000000000000000000000000000000000000000007641 204.0
TLS3_k127_3520211_2 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000000000000000000000000000000008263 186.0
TLS3_k127_3520211_3 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000003411 165.0
TLS3_k127_3520211_4 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000009454 155.0
TLS3_k127_3520386_0 metal-dependent phosphohydrolase, HD sub domain K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 433.0
TLS3_k127_3520386_1 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007322 383.0
TLS3_k127_3520386_2 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000001164 220.0
TLS3_k127_3520386_3 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000005104 175.0
TLS3_k127_3520386_4 PFAM diacylglycerol kinase K00901 - 2.7.1.107 0.00000000000000000000000000000000000005301 146.0
TLS3_k127_3520386_5 YqeY-like protein K09117 - - 0.0000000000000000000000000000000005625 136.0
TLS3_k127_3520386_6 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K07042 - 3.5.4.5 0.00000000000000000000000000000007581 130.0
TLS3_k127_3520386_7 Diguanylate cyclase - - - 0.000000000000000005663 95.0
TLS3_k127_3521413_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000001265 208.0
TLS3_k127_3521413_1 Proteins of 100 residues with WXG - - - 0.000000000000000000000000000000000000000000001251 169.0
TLS3_k127_3521413_2 ABC-type dipeptide transport system periplasmic component K02035 - - 0.0000000000000000000000000000000008751 149.0
TLS3_k127_3521413_3 PFAM RNA recognition motif - - - 0.0000000000000000000000000000001192 127.0
TLS3_k127_3521413_4 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000001505 123.0
TLS3_k127_3521413_5 Transposase DDE domain group 1 - - - 0.0000000000000000000000000002565 128.0
TLS3_k127_3521413_6 Stage II K07315 - 3.1.3.3 0.000000000000000001343 87.0
TLS3_k127_3521413_7 Transposase DDE domain group 1 - - - 0.0000007086 59.0
TLS3_k127_3551024_0 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000008608 205.0
TLS3_k127_3551024_1 - - - - 0.0000000000004797 76.0
TLS3_k127_3554453_0 Transmembrane secretion effector K08225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 508.0
TLS3_k127_3554453_1 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000000000000000000000000000000000001287 206.0
TLS3_k127_3554453_2 Protein of unknown function (DUF2892) - - - 0.000000000000000002151 86.0
TLS3_k127_3554453_3 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000004171 72.0
TLS3_k127_3554453_4 Peptidoglycan-binding LysM - - - 0.0000003694 62.0
TLS3_k127_3554453_5 - - - - 0.0000005219 53.0
TLS3_k127_3554453_6 zinc-ribbon family - - - 0.000005798 51.0
TLS3_k127_3563774_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 524.0
TLS3_k127_3563774_1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K12583 - - 0.0000000000000000004013 89.0
TLS3_k127_356703_0 PFAM Dak phosphatase K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 433.0
TLS3_k127_356703_1 PFAM GHMP kinase K00869 - 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000003043 254.0
TLS3_k127_356703_2 Asp23 family, cell envelope-related function - - - 0.000000000000000000000002399 106.0
TLS3_k127_3574408_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000101 218.0
TLS3_k127_3574408_1 PFAM Sodium Bile acid symporter family K03453 - - 0.000000000000000000000000000000000000000000000000000000000002564 218.0
TLS3_k127_3574408_2 ThiF family - - - 0.000000000000000000000000000000000000003379 158.0
TLS3_k127_3574408_3 BRO family, N-terminal domain - - - 0.0000000000000000000000000000068 134.0
TLS3_k127_3574408_4 Uncharacterised protein family (UPF0175) - - - 0.00000000000000000000001575 102.0
TLS3_k127_3574408_5 - - - - 0.000000000000002198 79.0
TLS3_k127_3574408_6 Phage plasmid primase P4 family - - - 0.00000000000008827 83.0
TLS3_k127_3574408_7 - - - - 0.00000000239 62.0
TLS3_k127_3574408_8 - - - - 0.00000003929 59.0
TLS3_k127_3574408_9 - - - - 0.0000000958 58.0
TLS3_k127_3587697_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 325.0
TLS3_k127_3587697_1 PFAM ABC transporter related K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000122 231.0
TLS3_k127_3587697_2 carbohydrate transport K02027,K10117,K11751 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000003766 187.0
TLS3_k127_3587697_3 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000002843 156.0
TLS3_k127_3591630_0 ATP-dependent peptidase activity K01338,K04076,K04770 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 610.0
TLS3_k127_3591630_1 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000004432 221.0
TLS3_k127_3591630_2 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000001425 165.0
TLS3_k127_3591630_3 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.00000001996 57.0
TLS3_k127_3592700_0 PFAM NmrA family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001403 263.0
TLS3_k127_3592700_1 DNA-templated transcription, initiation K03088 - - 0.0000002715 60.0
TLS3_k127_3592700_2 Pfam:DUF2029 - - - 0.0005927 51.0
TLS3_k127_3593286_0 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002928 252.0
TLS3_k127_3593286_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000009436 178.0
TLS3_k127_3593286_2 DinB family - - - 0.0000000000000000000000000000001798 130.0
TLS3_k127_3593286_3 serine threonine protein kinase - - - 0.00000000000003962 78.0
TLS3_k127_3604200_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000004374 182.0
TLS3_k127_3604200_1 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 0.00000000000000000000000000000000146 150.0
TLS3_k127_3604200_2 FtsX-like permease family K02004 - - 0.000000000000000000000002963 120.0
TLS3_k127_360588_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 570.0
TLS3_k127_360588_1 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000009903 231.0
TLS3_k127_360588_2 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000001648 228.0
TLS3_k127_360588_3 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.0000000000000000000000000000000000000641 147.0
TLS3_k127_360588_4 MazG-like family - - - 0.0000000000000000000000000002046 118.0
TLS3_k127_3633224_0 von Willebrand factor type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 360.0
TLS3_k127_3635381_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 360.0
TLS3_k127_3635381_1 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 326.0
TLS3_k127_3635381_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 296.0
TLS3_k127_3635381_3 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000009443 215.0
TLS3_k127_3635381_4 formate dehydrogenase - - - 0.00000000000001666 78.0
TLS3_k127_3642089_0 BFD domain protein 2Fe-2S -binding domain protein K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000001533 223.0
TLS3_k127_3642089_1 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000006739 222.0
TLS3_k127_3642089_2 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.0000000000000000000000000000000248 140.0
TLS3_k127_3642089_3 DoxX-like family - - - 0.0000000000000000001845 90.0
TLS3_k127_3646330_0 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000001807 233.0
TLS3_k127_3646330_1 Bacterial transcriptional repressor C-terminal K16137 - - 0.0000000000000000000000000000000000000000000000000000000000000005438 226.0
TLS3_k127_3646330_2 OsmC-like protein K09136 - - 0.00000000000000000000000000000000000000000000001025 174.0
TLS3_k127_3646330_3 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000001856 147.0
TLS3_k127_3646330_4 CoA binding domain - - - 0.00000000000000004332 89.0
TLS3_k127_3646330_5 Membrane - - - 0.0002629 52.0
TLS3_k127_3682641_0 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 358.0
TLS3_k127_3682641_1 protein ubiquitination K10464,K15046 GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005667,GO:0005681,GO:0005737,GO:0005829,GO:0005856,GO:0006139,GO:0006351,GO:0006383,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009605,GO:0009607,GO:0009615,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010467,GO:0010605,GO:0010646,GO:0010648,GO:0010941,GO:0016070,GO:0018130,GO:0019222,GO:0019438,GO:0023051,GO:0023057,GO:0031323,GO:0031324,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0032774,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051704,GO:0051707,GO:0060255,GO:0060548,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1902531,GO:1902532,GO:1903320,GO:1903321,GO:1990904,GO:2001233,GO:2001234,GO:2001242,GO:2001243 - 0.00000000002958 77.0
TLS3_k127_3682641_2 Belongs to the peptidase S8 family K14645 - - 0.00000000002958 77.0
TLS3_k127_3682641_3 Subtilase family - - - 0.000007716 59.0
TLS3_k127_3682641_4 Anticodon-binding domain of tRNA K01870 - 6.1.1.5 0.0000171 48.0
TLS3_k127_3696422_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1131.0
TLS3_k127_3696422_1 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 431.0
TLS3_k127_3696422_2 Heat shock protein DnaJ domain protein K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 340.0
TLS3_k127_3703050_0 Type III restriction enzyme res subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 507.0
TLS3_k127_3703050_1 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 437.0
TLS3_k127_3703050_2 Two component regulator propeller K00936 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 374.0
TLS3_k127_3703050_3 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000981 169.0
TLS3_k127_3703050_4 Protein of unknown function (DUF790) K09744 - - 0.00000005806 58.0
TLS3_k127_3706921_0 tail sheath protein K06907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002061 270.0
TLS3_k127_3706921_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000007406 226.0
TLS3_k127_3706921_2 GPW gp25 family protein K06903 - - 0.000000000000002317 84.0
TLS3_k127_3706921_3 Phage tail sheath protein subtilisin-like domain - - - 0.00000000000002313 87.0
TLS3_k127_3720399_0 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004003 278.0
TLS3_k127_3720399_1 CO dehydrogenase flavoprotein C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001019 262.0
TLS3_k127_3720399_2 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000008876 213.0
TLS3_k127_3720399_3 response regulator K07814 - - 0.00000000000000000000001043 105.0
TLS3_k127_3730553_0 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 409.0
TLS3_k127_3730553_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 344.0
TLS3_k127_3730553_2 Immune inhibitor A peptidase M6 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 344.0
TLS3_k127_3730553_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004554 269.0
TLS3_k127_3730553_4 TIGRFAM glutaredoxin-like domain protein - - - 0.000000000003185 73.0
TLS3_k127_3730553_5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000004517 63.0
TLS3_k127_3744208_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 443.0
TLS3_k127_3744208_1 Formate/nitrite transporter K06212 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 358.0
TLS3_k127_3744208_2 Peptidase family S58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002411 267.0
TLS3_k127_3744208_3 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000001365 221.0
TLS3_k127_3744208_4 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000003922 210.0
TLS3_k127_3744208_5 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000001747 164.0
TLS3_k127_3744208_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000000000000001671 92.0
TLS3_k127_3751364_0 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 470.0
TLS3_k127_3751364_1 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 364.0
TLS3_k127_3751364_2 PFAM Chorismate mutase of the AroH class K06208 - 5.4.99.5 0.0000000000000000000000000000000000000000000000000002692 190.0
TLS3_k127_3751364_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000001024 170.0
TLS3_k127_3751364_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000001422 108.0
TLS3_k127_3751437_0 amine dehydrogenase activity - - - 7.675e-291 906.0
TLS3_k127_3751437_1 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 434.0
TLS3_k127_3751437_2 alginic acid biosynthetic process - - - 0.000000000000000000000000000000006967 132.0
TLS3_k127_375574_0 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.000000000000000000000000000000005531 139.0
TLS3_k127_375574_1 - - - - 0.000000000000000004665 89.0
TLS3_k127_375574_2 WD-40 repeat protein - - - 0.00000000000001182 85.0
TLS3_k127_3765909_0 PFAM ABC transporter related K02028,K09972 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 392.0
TLS3_k127_3765909_1 Bacterial periplasmic substrate-binding proteins K10039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009126 379.0
TLS3_k127_3765909_2 amino acid transport K09970,K09971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004947 285.0
TLS3_k127_3765909_3 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K09971 - - 0.000000000000000000000000000000000000000000000005051 196.0
TLS3_k127_3766129_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.466e-215 678.0
TLS3_k127_3766129_1 PFAM amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001471 240.0
TLS3_k127_3766656_0 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000004108 134.0
TLS3_k127_3766656_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000008624 121.0
TLS3_k127_3766656_2 transcriptional regulator - - - 0.00000000000000000000000009435 119.0
TLS3_k127_378727_0 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 437.0
TLS3_k127_378727_1 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 408.0
TLS3_k127_378727_2 pilus organization K02674,K07004 - - 0.000000000000000000000000000000000000000000000000000000001084 229.0
TLS3_k127_378727_3 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000006372 204.0
TLS3_k127_378727_4 Domain of unknown function (DUF1905) - - - 0.00000000000000000000000000000000386 130.0
TLS3_k127_378727_5 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000003021 74.0
TLS3_k127_3789524_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 1.236e-303 945.0
TLS3_k127_3789524_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 344.0
TLS3_k127_3789524_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 292.0
TLS3_k127_3789524_3 amino acid-binding ACT domain protein K04767 - - 0.0000000000000000000000000000001536 132.0
TLS3_k127_3795042_0 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 392.0
TLS3_k127_3795042_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 339.0
TLS3_k127_3795042_2 Two component transcriptional regulator, winged helix family K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 324.0
TLS3_k127_3795042_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 302.0
TLS3_k127_3795042_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000002825 144.0
TLS3_k127_3795042_5 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.00000000000000003761 81.0
TLS3_k127_3795042_6 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000001516 68.0
TLS3_k127_3810517_0 PFAM glycoside hydrolase family 65 central catalytic - - - 5.919e-287 910.0
TLS3_k127_3810517_1 helix_turn _helix lactose operon repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 340.0
TLS3_k127_3810517_2 ABC transporter, substratebinding protein K02035 - - 0.0003525 44.0
TLS3_k127_3848301_0 homoserine dehydrogenase - - - 2.789e-195 617.0
TLS3_k127_3848301_1 COGs COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000499 421.0
TLS3_k127_3848301_10 PFAM Sulfotransferase domain - - - 0.0000000000000000000000000000001208 137.0
TLS3_k127_3848301_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008285 340.0
TLS3_k127_3848301_4 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000001187 251.0
TLS3_k127_3848301_5 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000235 234.0
TLS3_k127_3848301_6 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000003478 224.0
TLS3_k127_3848301_7 Galactose-3-O-sulfotransferase - - - 0.0000000000000000000000000000000000000000000000000000004749 204.0
TLS3_k127_3848301_8 lipolytic protein G-D-S-L family K01278,K03561,K12287 - 3.4.14.5 0.000000000000000000000000000000000006057 148.0
TLS3_k127_3848301_9 PFAM Bacterial transferase hexapeptide (three repeats) - - - 0.0000000000000000000000000000000004233 134.0
TLS3_k127_3871701_0 trimethylamine methyltransferase K14083 - 2.1.1.250 7.745e-220 693.0
TLS3_k127_3871701_1 Cytochrome C oxidase subunit I K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 602.0
TLS3_k127_3871701_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 397.0
TLS3_k127_3871701_3 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000009588 229.0
TLS3_k127_3871701_4 Ferric reductase like transmembrane component K09792 - - 0.0000000000000000059 94.0
TLS3_k127_3871701_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000001062 68.0
TLS3_k127_3911356_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 3.76e-259 814.0
TLS3_k127_3911356_1 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000004554 211.0
TLS3_k127_3911356_2 Protein of unknown function (DUF3124) - - - 0.00000000000000000000000000000000000008577 149.0
TLS3_k127_3911839_0 PFAM O-antigen polymerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 387.0
TLS3_k127_3911839_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0001006 53.0
TLS3_k127_3922870_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000007092 147.0
TLS3_k127_3922870_1 SMART tyrosine protein kinase - - - 0.0000000000000006669 89.0
TLS3_k127_3922870_2 ribosome binding - - - 0.000326 52.0
TLS3_k127_3928445_0 protein histidine kinase activity K01768,K11527,K18143 - 2.7.13.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 323.0
TLS3_k127_3928445_1 protein methyltransferase activity K11434,K15984,K20421 - 2.1.1.242,2.1.1.303,2.1.1.319 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 292.0
TLS3_k127_3928445_2 PFAM Signal transduction response regulator, receiver domain - - - 0.000000000000000000000000000601 117.0
TLS3_k127_3928445_3 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000003335 116.0
TLS3_k127_3941560_0 PFAM MOSC domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001886 233.0
TLS3_k127_3941560_1 TIGRFAM uracil-DNA glycosylase, family 4 K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000001039 213.0
TLS3_k127_3941560_2 PFAM Methyltransferase type 11 - - - 0.000000000000003598 78.0
TLS3_k127_3946445_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001854 271.0
TLS3_k127_3950137_0 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 394.0
TLS3_k127_3950137_1 ADP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 389.0
TLS3_k127_3950137_2 Methyltransferase, type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 355.0
TLS3_k127_3950345_0 Nacht domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 508.0
TLS3_k127_3950345_1 ROK family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 449.0
TLS3_k127_3950345_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000851 80.0
TLS3_k127_3955131_0 Non-ribosomal peptide synthetase modules and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 444.0
TLS3_k127_3955131_1 COG1020 Non-ribosomal peptide synthetase modules and related proteins - - - 0.000000000000000000000000000000000000000000000000000000006587 219.0
TLS3_k127_3958296_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 598.0
TLS3_k127_3958296_1 Metallo-beta-lactamase superfamily domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 571.0
TLS3_k127_3958296_2 PFAM type II secretion system protein K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004596 274.0
TLS3_k127_3958296_3 PFAM type II secretion system protein K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001842 267.0
TLS3_k127_3958296_4 NIF3 (NGG1p interacting factor 3) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003664 249.0
TLS3_k127_3958296_5 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000007092 172.0
TLS3_k127_3958296_6 competence protein - - - 0.000000000000000000000000000000000000000000000822 174.0
TLS3_k127_3958296_7 PFAM low molecular weight phosphotyrosine protein phosphatase K01104 - 3.1.3.48 0.0000000000000000000000000000000000473 139.0
TLS3_k127_3958296_8 RecQ zinc-binding K03654 - 3.6.4.12 0.0001959 47.0
TLS3_k127_3963870_0 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 358.0
TLS3_k127_3963870_1 Predicted integral membrane protein (DUF2270) - - - 0.000000000000000000000000000000000000000000000000000000000001455 222.0
TLS3_k127_3963870_2 membrane - - - 0.000000000000000000000000000000000000000000000000001831 187.0
TLS3_k127_3963870_3 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000000000000000000002212 175.0
TLS3_k127_3963870_4 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000007738 169.0
TLS3_k127_3963870_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000001141 99.0
TLS3_k127_3963870_6 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.00000000000002077 85.0
TLS3_k127_3973104_0 Aldehyde dehydrogenase family K00141 - 1.2.1.28 2.696e-215 676.0
TLS3_k127_3973104_1 Aminomethyltransferase folate-binding domain K15066 - 2.1.1.341 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 283.0
TLS3_k127_3973104_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000004688 77.0
TLS3_k127_3983938_0 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 288.0
TLS3_k127_3983938_1 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000000000001244 205.0
TLS3_k127_3983938_2 SNARE associated Golgi protein - - - 0.0000000000000000000000000000005745 126.0
TLS3_k127_399220_0 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000003101 238.0
TLS3_k127_399220_1 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE - - - 0.0000000000000000000000000000000000000000000000000000000000000000942 222.0
TLS3_k127_399220_2 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000226 167.0
TLS3_k127_399220_3 Transcriptional regulator K02854,K02855 - - 0.00006391 50.0
TLS3_k127_3994009_0 leucyl-tRNA aminoacylation K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 1.852e-269 853.0
TLS3_k127_3994009_1 peptidyl-tyrosine sulfation K00525,K01768 - 1.17.4.1,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000003127 220.0
TLS3_k127_3994009_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000004363 205.0
TLS3_k127_3994009_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000001806 156.0
TLS3_k127_3994009_4 LysM domain K03642,K03791,K22278 - 3.5.1.104 0.0000000000000000000001546 103.0
TLS3_k127_3994009_5 ubiE/COQ5 methyltransferase family - - - 0.0000355 46.0
TLS3_k127_3994009_6 Uncharacterized conserved protein (DUF2293) - - - 0.0001944 45.0
TLS3_k127_4007914_0 Fibronectin type III-like domain K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 350.0
TLS3_k127_4007914_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000006125 183.0
TLS3_k127_4007914_2 Serine aminopeptidase, S33 - - - 0.00000006845 58.0
TLS3_k127_4011536_0 Protein of unknown function (DUF2723) - - - 0.000000000000000000000000000000000006574 158.0
TLS3_k127_404318_0 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 439.0
TLS3_k127_404318_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 405.0
TLS3_k127_404318_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000000001097 142.0
TLS3_k127_404318_3 COG COG0457 FOG TPR repeat - - - 0.0007534 50.0
TLS3_k127_4044498_0 FtsX-like permease family K02004 - - 9.857e-207 666.0
TLS3_k127_4044498_1 PFAM ABC transporter related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 361.0
TLS3_k127_4044498_2 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006037 244.0
TLS3_k127_406214_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 407.0
TLS3_k127_406214_1 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 289.0
TLS3_k127_406214_2 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006995 261.0
TLS3_k127_406214_3 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000006069 197.0
TLS3_k127_406214_4 - - - - 0.000000009245 61.0
TLS3_k127_406214_5 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.0005948 42.0
TLS3_k127_4066290_0 carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 447.0
TLS3_k127_4066290_1 YoaP-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 406.0
TLS3_k127_4066290_2 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 313.0
TLS3_k127_4066290_3 Mate efflux family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001912 279.0
TLS3_k127_4066290_4 Response regulator receiver K07670 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000203 76.0
TLS3_k127_4066442_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 501.0
TLS3_k127_4066442_1 Tellurite resistance protein TerB - - - 0.000000000000000000000000000000000000000000000000000000000000000006905 236.0
TLS3_k127_4066442_2 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000003914 224.0
TLS3_k127_4066442_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.00000000000000000000000000000000000000000009692 162.0
TLS3_k127_4066442_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000002585 143.0
TLS3_k127_4066442_5 YbbR-like protein - - - 0.0000000000000000000000000000000000004694 156.0
TLS3_k127_4066442_6 LppX_LprAFG lipoprotein K14954 - - 0.00000000000000000006211 99.0
TLS3_k127_4066442_7 Domain of unknown function (DUF4259) - - - 0.0000000000000002294 84.0
TLS3_k127_4070001_0 Belongs to the glycosyl hydrolase 2 family - - - 2.192e-197 636.0
TLS3_k127_4070001_1 Glycosyltransferase family 28 N-terminal domain K05841 - 2.4.1.173 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 533.0
TLS3_k127_4070001_10 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000001178 109.0
TLS3_k127_4070001_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 529.0
TLS3_k127_4070001_3 PFAM Adenosine AMP deaminase K01488,K18286 - 3.5.4.4,3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 454.0
TLS3_k127_4070001_4 COG1131 ABC-type multidrug transport system ATPase component K16907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 360.0
TLS3_k127_4070001_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000001965 262.0
TLS3_k127_4070001_6 ATPase, P-type transporting, HAD superfamily, subfamily IC K16905 - - 0.00000000000000000000000000000000000000000000000000000000000000001439 231.0
TLS3_k127_4070001_7 Domain of unknown function (DUF348) - - - 0.00000000000000000000000000000000000000000000000000000000000000002387 242.0
TLS3_k127_4070001_8 transmembrane transport K16906 - - 0.000000000000000000000000000000000000000000000000000000004295 207.0
TLS3_k127_4070001_9 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000000000000006991 195.0
TLS3_k127_407064_0 thiosulfate sulfurtransferase activity K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 341.0
TLS3_k127_407064_1 regulatory protein LysR K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000001143 234.0
TLS3_k127_407064_2 - - - - 0.00000000000000000000000000000000000000000000000000519 187.0
TLS3_k127_407064_3 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000000000001373 136.0
TLS3_k127_4093445_0 SPFH domain / Band 7 family - - - 3.613e-257 807.0
TLS3_k127_4093445_1 cellulase activity K01183 - 3.2.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000005698 262.0
TLS3_k127_4093445_2 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000003609 227.0
TLS3_k127_4093445_3 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000426 154.0
TLS3_k127_4093445_4 Cysteine-rich secretory protein family - - - 0.00000000004335 75.0
TLS3_k127_4104914_0 oxidoreductase activity - - - 3.636e-201 642.0
TLS3_k127_4104914_1 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.0000000000003653 74.0
TLS3_k127_4117325_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 1.385e-195 623.0
TLS3_k127_4117325_1 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003712 289.0
TLS3_k127_4117325_2 IMG reference gene - - - 0.0000000393 58.0
TLS3_k127_4117325_4 Diguanylate cyclase - - - 0.0001035 53.0
TLS3_k127_4129063_0 (ABC) transporter K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 529.0
TLS3_k127_4129063_1 LysM domain - - - 0.0006581 50.0
TLS3_k127_4150513_0 cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 360.0
TLS3_k127_4150513_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003065 252.0
TLS3_k127_4150513_2 PFAM ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005998 250.0
TLS3_k127_4150513_3 WD40 repeats K20332 - - 0.00000000000000000000000001545 128.0
TLS3_k127_4150513_4 Cellulase N-terminal ig-like domain K01179 - 3.2.1.4 0.000000000000000001979 91.0
TLS3_k127_4153816_0 intracellular signal transduction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 368.0
TLS3_k127_4153816_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 320.0
TLS3_k127_4153816_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 292.0
TLS3_k127_4153816_3 PFAM metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005492 249.0
TLS3_k127_4153816_5 DHHA2 K15986 - 3.6.1.1 0.0000000000000000001556 93.0
TLS3_k127_4156776_0 Predicted membrane protein (DUF2079) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 449.0
TLS3_k127_4156776_1 membrane - - - 0.00000000000000000000001151 115.0
TLS3_k127_4156776_2 oligosaccharyl transferase activity - - - 0.00000005098 60.0
TLS3_k127_4172711_0 polyketide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 526.0
TLS3_k127_4172711_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000003886 180.0
TLS3_k127_4180560_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 303.0
TLS3_k127_4180560_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003268 272.0
TLS3_k127_4180560_2 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002619 235.0
TLS3_k127_4180560_3 TRAP transporter solute receptor, TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000008046 230.0
TLS3_k127_4180560_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000008085 178.0
TLS3_k127_4180560_5 PFAM cytoplasmic chaperone TorD family protein - - - 0.0000000000000000000000000000000000000892 149.0
TLS3_k127_4192445_0 Belongs to the peptidase S8 family K13276 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 323.0
TLS3_k127_4192445_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000006081 239.0
TLS3_k127_4192445_2 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.000000002941 72.0
TLS3_k127_420999_0 Glycosyltransferase like family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000003372 244.0
TLS3_k127_420999_1 Methyltransferase type 11 K20444 - - 0.000000000000000000006193 99.0
TLS3_k127_4214094_0 PFAM ABC transporter related K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 518.0
TLS3_k127_4214094_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000000000000000000000000000000000000000000000005114 218.0
TLS3_k127_4214094_2 Molecular chaperone. Has ATPase activity - - - 0.000000000000000000000000000000000000000000000000002753 204.0
TLS3_k127_4214094_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000001419 131.0
TLS3_k127_4214094_4 AMP binding - - - 0.0000000000000000000000000884 113.0
TLS3_k127_4214094_5 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000007304 115.0
TLS3_k127_4217680_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 510.0
TLS3_k127_4217680_1 PFAM LmbE family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002127 240.0
TLS3_k127_4219582_0 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01457 - 3.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 433.0
TLS3_k127_4219582_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000009135 241.0
TLS3_k127_4219582_2 acyl-CoA dehydrogenase activity K09456 - - 0.0000000000000000000000000000000000000000000333 166.0
TLS3_k127_4223479_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 482.0
TLS3_k127_4223479_1 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 423.0
TLS3_k127_4223479_2 PFAM O-antigen polymerase - - - 0.0000000000000000000000000000000000000000000000000000000000004352 228.0
TLS3_k127_4241250_0 ABC transporter K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 579.0
TLS3_k127_4241250_1 TIGRFAM TraB family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 405.0
TLS3_k127_4241250_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 379.0
TLS3_k127_4241971_0 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000005143 197.0
TLS3_k127_4241971_1 bacterial-type flagellum-dependent cell motility K15923 - 3.2.1.51 0.000000000000000000000000000000000006077 140.0
TLS3_k127_4241971_2 Smr domain - - - 0.000000000000000000000000000000001241 132.0
TLS3_k127_4249750_0 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 504.0
TLS3_k127_4249750_1 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 455.0
TLS3_k127_4249750_2 Shikimate quinate 5-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 389.0
TLS3_k127_4249750_3 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 369.0
TLS3_k127_4249750_4 TIGRFAM small GTP-binding protein K06945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008893 289.0
TLS3_k127_4249750_5 4-vinyl reductase, 4VR - - - 0.00000000000000000000000000000000000000000000000000000000000000006274 229.0
TLS3_k127_4249750_6 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000003275 230.0
TLS3_k127_4249750_7 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000004129 211.0
TLS3_k127_4249750_8 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000001378 154.0
TLS3_k127_4261826_0 Two component transcriptional regulator, winged helix family K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004515 273.0
TLS3_k127_4261826_1 histidine kinase HAMP region domain protein K02484,K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000008594 228.0
TLS3_k127_4261826_2 ABC transporter K02003 - - 0.0000000000000000000000000000002449 125.0
TLS3_k127_4270325_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 561.0
TLS3_k127_4270325_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 519.0
TLS3_k127_4270325_2 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 420.0
TLS3_k127_4270325_3 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 367.0
TLS3_k127_4270325_4 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 355.0
TLS3_k127_4270325_5 TIGRFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 312.0
TLS3_k127_4270325_6 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000007198 246.0
TLS3_k127_4274020_0 glutamate-cysteine ligase activity K00836 - 2.6.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 518.0
TLS3_k127_4274020_1 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 331.0
TLS3_k127_4274020_2 ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003703 250.0
TLS3_k127_4274020_3 Aminoacyl-tRNA editing domain - - - 0.00000000000000000000000000000000000000000008571 164.0
TLS3_k127_4287846_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 475.0
TLS3_k127_4287846_1 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 462.0
TLS3_k127_4287846_2 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 338.0
TLS3_k127_429532_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 522.0
TLS3_k127_429532_1 5'-nucleotidase, C-terminal domain K11751 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000001424 245.0
TLS3_k127_4316675_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.159e-198 632.0
TLS3_k127_4316675_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756,K01857 - 4.3.2.2,5.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 531.0
TLS3_k127_4316675_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000483 165.0
TLS3_k127_4325890_0 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007777 543.0
TLS3_k127_4325890_1 CHAT domain - - - 0.000000009953 65.0
TLS3_k127_4325890_2 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000006013 48.0
TLS3_k127_4329942_0 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009024 492.0
TLS3_k127_4329942_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000001363 169.0
TLS3_k127_4329942_2 YGGT family K02221 - - 0.00000000000000003702 84.0
TLS3_k127_4334600_0 Belongs to the ATP-dependent AMP-binding enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 565.0
TLS3_k127_4334600_1 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000003427 241.0
TLS3_k127_4334600_2 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000001564 65.0
TLS3_k127_4334600_3 Belongs to the P-Pant transferase superfamily K06133 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000004884 52.0
TLS3_k127_434489_0 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 6.553e-198 622.0
TLS3_k127_434489_1 Nucleotidyl transferase K00973 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 441.0
TLS3_k127_434489_10 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000000002192 157.0
TLS3_k127_434489_11 PFAM peptidase M22 glycoprotease K14742 - - 0.00000000000000000000000000000000000001329 152.0
TLS3_k127_434489_12 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000000000003889 149.0
TLS3_k127_434489_14 Domain of unknown function (DUF4349) - - - 0.000000000000000000000000000000006499 142.0
TLS3_k127_434489_15 Uncharacterised protein family (UPF0175) - - - 0.0000000000000000000000000000000966 125.0
TLS3_k127_434489_16 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000002106 126.0
TLS3_k127_434489_17 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000001753 64.0
TLS3_k127_434489_2 short-chain dehydrogenase reductase SDR K12454 - 5.1.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 438.0
TLS3_k127_434489_3 PFAM NMT1 THI5 like domain protein K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 306.0
TLS3_k127_434489_4 Peroxisomal multifunctional enzyme type K12405,K14729 GO:0000003,GO:0000038,GO:0002064,GO:0003006,GO:0003674,GO:0003824,GO:0003857,GO:0004303,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0006066,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0007548,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008209,GO:0008210,GO:0008406,GO:0008584,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009719,GO:0009725,GO:0009888,GO:0009987,GO:0010033,GO:0010817,GO:0014070,GO:0016042,GO:0016054,GO:0016125,GO:0016229,GO:0016491,GO:0016508,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0019395,GO:0019637,GO:0019693,GO:0019752,GO:0022414,GO:0030154,GO:0030258,GO:0030283,GO:0030855,GO:0031907,GO:0031974,GO:0032501,GO:0032502,GO:0032787,GO:0033764,GO:0033865,GO:0033875,GO:0033993,GO:0034032,GO:0034440,GO:0034641,GO:0034754,GO:0035337,GO:0035383,GO:0036111,GO:0036112,GO:0042221,GO:0042445,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0044594,GO:0045137,GO:0046395,GO:0046483,GO:0046546,GO:0046661,GO:0046983,GO:0048468,GO:0048513,GO:0048545,GO:0048608,GO:0048731,GO:0048856,GO:0048869,GO:0050896,GO:0051186,GO:0051716,GO:0055086,GO:0055114,GO:0060008,GO:0060009,GO:0060429,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901568,GO:1901575,GO:1901615,GO:1902652 1.1.1.35,4.2.1.107,4.2.1.119 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 294.0
TLS3_k127_434489_5 PFAM metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001321 255.0
TLS3_k127_434489_6 Contains PIN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003406 231.0
TLS3_k127_434489_7 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000003964 220.0
TLS3_k127_434489_8 PFAM binding-protein-dependent transport systems inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000008817 173.0
TLS3_k127_434489_9 PFAM MazG nucleotide pyrophosphohydrolase - - - 0.0000000000000000000000000000000000000000000008676 167.0
TLS3_k127_4353872_0 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000001436 194.0
TLS3_k127_4353872_1 inorganic diphosphatase activity K15986 - 3.6.1.1 0.000000000000000000000000000000000000002734 154.0
TLS3_k127_4353872_2 Belongs to the peptidase S8 family - - - 0.000000000000000000003935 104.0
TLS3_k127_4353872_3 protein kinase activity - - - 0.000000000001214 72.0
TLS3_k127_4353872_4 DinB superfamily - - - 0.0006324 48.0
TLS3_k127_4354605_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 589.0
TLS3_k127_4354605_1 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 411.0
TLS3_k127_4354605_2 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 313.0
TLS3_k127_4354605_3 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004649 267.0
TLS3_k127_4354605_4 spore germination - - - 0.000000000000000000000000000000000000000000000000001195 199.0
TLS3_k127_4356529_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 436.0
TLS3_k127_4356529_1 ADP-glyceromanno-heptose 6-epimerase activity K01709 - 4.2.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 394.0
TLS3_k127_4356529_2 TIGRFAM Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.000000000000000000000000000000000000000000000000000000000000001775 227.0
TLS3_k127_4356529_3 Type ii secretion system K12510 - - 0.000000006541 62.0
TLS3_k127_4356788_0 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000907 215.0
TLS3_k127_4356788_1 PFAM Ubiquitin-conjugating - - - 0.0000000000000000000000000005238 119.0
TLS3_k127_4356788_2 PFAM Mov34 MPN PAD-1 family - - - 0.00000000000000000000002639 113.0
TLS3_k127_4356788_3 WXG100 protein secretion system (Wss), protein YukD - - - 0.00000000000006419 75.0
TLS3_k127_4368817_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 480.0
TLS3_k127_4368817_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 408.0
TLS3_k127_4368817_2 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.0000000000000000000000000000000000003586 148.0
TLS3_k127_4368817_3 Cytochrome c K17222 - - 0.000000000000000000000001886 113.0
TLS3_k127_4368817_4 - - - - 0.00009637 49.0
TLS3_k127_4373029_0 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000005427 186.0
TLS3_k127_4373029_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000003123 195.0
TLS3_k127_4373029_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000007639 187.0
TLS3_k127_4373029_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000009862 148.0
TLS3_k127_4382821_0 SMART von Willebrand factor, type A K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 394.0
TLS3_k127_4382821_1 endonuclease III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 318.0
TLS3_k127_4382821_2 XdhC and CoxI family - - - 0.000000000000000000000000000000000007169 143.0
TLS3_k127_4383325_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 400.0
TLS3_k127_4383325_1 TIGRFAM polymorphic outer membrane protein - - - 0.00000000000000000000000005305 121.0
TLS3_k127_4383325_2 Globin - - - 0.0000000000000000001269 94.0
TLS3_k127_4383325_3 - - - - 0.000000000000000002076 100.0
TLS3_k127_4385540_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K02056,K10545,K10548 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005975,GO:0005996,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015148,GO:0015749,GO:0015750,GO:0015753,GO:0017076,GO:0019321,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042732,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 9.228e-206 652.0
TLS3_k127_4385540_1 Periplasmic binding protein domain K10543,K10546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 537.0
TLS3_k127_4385540_2 response regulator K07669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 394.0
TLS3_k127_4385540_3 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000001184 270.0
TLS3_k127_4389216_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 533.0
TLS3_k127_4389216_1 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 453.0
TLS3_k127_4389216_2 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000002581 121.0
TLS3_k127_4425442_0 Acetyl propionyl-CoA carboxylase, alpha subunit K13777 - 6.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 457.0
TLS3_k127_4425442_1 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 344.0
TLS3_k127_4425442_2 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000438 267.0
TLS3_k127_4425442_3 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000003054 214.0
TLS3_k127_4425442_4 phosphorelay signal transduction system - - - 0.000000000000000000000000008023 118.0
TLS3_k127_4425442_5 TIGRFAM Lysine biosynthesis protein LysW K05826 - - 0.0000007937 54.0
TLS3_k127_4425442_6 TIGRFAM Lysine biosynthesis protein LysW K05826 - - 0.0004295 47.0
TLS3_k127_4428525_0 PFAM ABC transporter related K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 580.0
TLS3_k127_4428525_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 449.0
TLS3_k127_4428525_10 Mazg nucleotide pyrophosphohydrolase - - - 0.000000000000000002035 88.0
TLS3_k127_4428525_11 Belongs to the GbsR family - - - 0.000000000000001626 83.0
TLS3_k127_4428525_12 NurA - - - 0.00000000000001253 83.0
TLS3_k127_4428525_13 SPTR PilT protein domain protein - - - 0.00000000000002869 74.0
TLS3_k127_4428525_14 sequence-specific DNA binding - - - 0.000000000002353 69.0
TLS3_k127_4428525_15 PIN domain - - - 0.0000000003755 63.0
TLS3_k127_4428525_16 - - - - 0.0000002007 55.0
TLS3_k127_4428525_17 Tetratricopeptide repeat - - - 0.00000362 54.0
TLS3_k127_4428525_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 358.0
TLS3_k127_4428525_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 316.0
TLS3_k127_4428525_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000001357 241.0
TLS3_k127_4428525_5 PFAM NAD-dependent epimerase dehydratase K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000001294 179.0
TLS3_k127_4428525_6 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000006394 183.0
TLS3_k127_4428525_7 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - - - 0.00000000000000000000000000000000000001969 149.0
TLS3_k127_4428525_8 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000000003744 138.0
TLS3_k127_4428525_9 - - - - 0.00000000000000000000001303 102.0
TLS3_k127_4438_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 302.0
TLS3_k127_4438_1 DNA-binding transcription factor activity K03892 - - 0.0000000000000000000000000000000004892 138.0
TLS3_k127_4441283_0 Alpha mannosidase, middle domain K01191 - 3.2.1.24 0.0 1219.0
TLS3_k127_4441283_1 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009636 304.0
TLS3_k127_4441283_2 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000000000000000000000000003098 224.0
TLS3_k127_4441283_3 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000002771 175.0
TLS3_k127_4441283_4 PFAM peptidase S16 lon domain protein K07157 - - 0.000000000000000000000000000000001868 137.0
TLS3_k127_4451017_0 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004284 271.0
TLS3_k127_4451017_1 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000003586 145.0
TLS3_k127_4451017_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000403 112.0
TLS3_k127_4457725_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 6.928e-229 731.0
TLS3_k127_4457725_1 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 338.0
TLS3_k127_4459524_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1140.0
TLS3_k127_4459524_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 548.0
TLS3_k127_4459524_10 - - - - 0.000000000000000000000000000000000001002 141.0
TLS3_k127_4459524_11 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.00000000000000000000000000001787 123.0
TLS3_k127_4459524_12 Domain of unknown function (DUF1330) - - - 0.000000000000000000007077 95.0
TLS3_k127_4459524_14 - - - - 0.0000000000002041 78.0
TLS3_k127_4459524_16 - - - - 0.0000000001449 72.0
TLS3_k127_4459524_18 NUDIX hydrolase - - - 0.0000001827 59.0
TLS3_k127_4459524_19 - - - - 0.0000003057 58.0
TLS3_k127_4459524_2 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008841 432.0
TLS3_k127_4459524_20 deaminase - GO:0003674,GO:0003824,GO:0004131,GO:0005488,GO:0006139,GO:0006206,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009112,GO:0009451,GO:0009987,GO:0016070,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0019858,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:1901360,GO:1901564 - 0.000001328 51.0
TLS3_k127_4459524_3 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 347.0
TLS3_k127_4459524_4 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000892 282.0
TLS3_k127_4459524_5 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000006957 268.0
TLS3_k127_4459524_6 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000003021 197.0
TLS3_k127_4459524_7 PFAM Stage II sporulation E family protein K01079,K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000009004 191.0
TLS3_k127_4459524_8 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000000000319 164.0
TLS3_k127_4459524_9 belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000006075 145.0
TLS3_k127_4462470_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.577e-230 730.0
TLS3_k127_4462470_1 N-terminal 7TM region of histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 402.0
TLS3_k127_4462470_10 - - - - 0.0006524 42.0
TLS3_k127_4462470_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 332.0
TLS3_k127_4462470_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 322.0
TLS3_k127_4462470_4 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003397 284.0
TLS3_k127_4462470_5 PFAM inositol monophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002923 278.0
TLS3_k127_4462470_6 SMART serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001489 274.0
TLS3_k127_4462470_7 PFAM PKD domain containing protein - - - 0.0000000000000000000000482 116.0
TLS3_k127_4462470_8 TIGRFAM phosphoesterase, MJ0936 family K07095 - - 0.00000000000000000005082 100.0
TLS3_k127_4462470_9 Cysteine-rich secretory protein family - - - 0.00000000000000000006548 106.0
TLS3_k127_446678_0 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 572.0
TLS3_k127_446678_1 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 567.0
TLS3_k127_446678_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008853 514.0
TLS3_k127_446678_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 380.0
TLS3_k127_446678_4 methionine synthase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006897 376.0
TLS3_k127_446678_5 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009873 314.0
TLS3_k127_446678_6 methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 295.0
TLS3_k127_446678_7 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008892 281.0
TLS3_k127_446678_8 SMART HNH nuclease - - - 0.00000000000000000000000000000000206 135.0
TLS3_k127_446678_9 oligosaccharyl transferase activity - - - 0.00000000004159 68.0
TLS3_k127_4483524_0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K09065 - 2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 556.0
TLS3_k127_4483524_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 522.0
TLS3_k127_4483524_2 hydratase' K02509 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 353.0
TLS3_k127_4483524_3 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001183 269.0
TLS3_k127_4483524_4 UTRA K03710 - - 0.00000000000000000613 93.0
TLS3_k127_4489353_0 formate dehydrogenase (NAD+) activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004101 279.0
TLS3_k127_4489353_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000002913 203.0
TLS3_k127_4489353_2 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000001538 181.0
TLS3_k127_4489353_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000007447 177.0
TLS3_k127_4489353_4 Cupin 2, conserved barrel domain protein - - - 0.000002892 55.0
TLS3_k127_4491734_0 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 427.0
TLS3_k127_4491734_1 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005596 275.0
TLS3_k127_4491734_2 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000004387 242.0
TLS3_k127_4491734_3 PASTA K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000000000000000000000002348 108.0
TLS3_k127_4491734_4 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000259 97.0
TLS3_k127_4492412_0 (ABC) transporter K06147 - - 6.484e-227 719.0
TLS3_k127_4492412_1 Fibronectin type III-like domain K05349 - 3.2.1.21 3.586e-198 634.0
TLS3_k127_4492412_2 purine nucleotide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 437.0
TLS3_k127_4492412_3 cellulase activity K01183 - 3.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 369.0
TLS3_k127_4492412_4 ABC-type multidrug transport system ATPase and permease K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003669 278.0
TLS3_k127_4492412_5 Aminoglycoside phosphotransferase - - - 0.000000000000000000000002411 115.0
TLS3_k127_4492412_6 protein targeting K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0000000000001225 79.0
TLS3_k127_4492412_7 cysteine-type peptidase activity - - - 0.00000001329 66.0
TLS3_k127_4492412_8 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.000007511 51.0
TLS3_k127_4508677_0 Secreted and surface protein containing fasciclin-like repeats K19519 - - 0.00000000000000000000000000000000000000000000000000003598 199.0
TLS3_k127_4508677_1 NACHT domain - - - 0.000000000802 72.0
TLS3_k127_4508677_2 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0006078 53.0
TLS3_k127_4518011_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 457.0
TLS3_k127_4518011_1 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 346.0
TLS3_k127_4518011_2 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003769 264.0
TLS3_k127_4518011_3 Sulfate ABC transporter periplasmic sulfate-binding protein K02048 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000695 218.0
TLS3_k127_4518011_4 ATPase-coupled sulfate transmembrane transporter activity K02046,K02047 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000001808 190.0
TLS3_k127_4518011_5 PFAM Integrase catalytic region K07497 - - 0.0000000000000000000000000000003397 131.0
TLS3_k127_4518011_6 Acts as a magnesium transporter K06213 - - 0.0000000000000000000363 93.0
TLS3_k127_4518011_7 DNA integration - - - 0.00002219 50.0
TLS3_k127_4518011_8 response regulator K02483 - - 0.00004649 48.0
TLS3_k127_451948_0 ABC transporter transmembrane region K06147 - - 8.657e-241 758.0
TLS3_k127_451948_1 ABC transporter transmembrane region K06147 - - 1.854e-230 730.0
TLS3_k127_451948_2 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 311.0
TLS3_k127_451948_3 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000002605 153.0
TLS3_k127_4519726_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000001332 279.0
TLS3_k127_4519726_1 nitroreductase - - - 0.00000000000000005561 83.0
TLS3_k127_4528965_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 310.0
TLS3_k127_4528965_1 PFAM sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001222 245.0
TLS3_k127_4528965_2 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000002314 243.0
TLS3_k127_4528965_3 integral membrane protein - - - 0.0000000000000000000376 96.0
TLS3_k127_4534048_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1267.0
TLS3_k127_4534048_1 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 387.0
TLS3_k127_4534048_2 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 336.0
TLS3_k127_4538380_0 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 367.0
TLS3_k127_4538380_1 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000000000000001014 132.0
TLS3_k127_4538380_2 - - - - 0.000000000000000000000002794 111.0
TLS3_k127_4538380_3 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749 - - 0.00000000000000000001541 93.0
TLS3_k127_4538380_4 PFAM response regulator receiver K03413 - - 0.000000000000017 78.0
TLS3_k127_4552976_0 Fibronectin type III-like domain K05349 - 3.2.1.21 6.993e-314 980.0
TLS3_k127_4552976_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 6.831e-247 766.0
TLS3_k127_4552976_2 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 510.0
TLS3_k127_4552976_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 478.0
TLS3_k127_4552976_4 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000788 441.0
TLS3_k127_4552976_5 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 407.0
TLS3_k127_4555730_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005661 257.0
TLS3_k127_4555730_1 serine-type endopeptidase activity K04771,K08372 - 3.4.21.107 0.000005224 55.0
TLS3_k127_4562017_0 Glycyl-tRNA synthetase alpha subunit K14164 - 6.1.1.14 5.38e-227 726.0
TLS3_k127_4562017_1 ECF sigma factor K03088 - - 0.000000000000000000000000000000000002144 144.0
TLS3_k127_4562017_2 Anti-sigma-K factor rskA - - - 0.0000004853 60.0
TLS3_k127_456781_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000002875 71.0
TLS3_k127_456781_1 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.000009084 58.0
TLS3_k127_4570641_0 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000003657 246.0
TLS3_k127_4570641_1 ABC transporter, transmembrane region K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000004342 219.0
TLS3_k127_4570641_2 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000004095 129.0
TLS3_k127_4570641_3 GAF domain K18438 GO:0000302,GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0006935,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0007275,GO:0007568,GO:0007602,GO:0007610,GO:0007635,GO:0008081,GO:0008150,GO:0008340,GO:0009268,GO:0009314,GO:0009416,GO:0009581,GO:0009582,GO:0009583,GO:0009605,GO:0009628,GO:0009636,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010035,GO:0010259,GO:0010446,GO:0010468,GO:0010604,GO:0010628,GO:0010646,GO:0010648,GO:0010752,GO:0010754,GO:0016043,GO:0016787,GO:0016788,GO:0019222,GO:0023051,GO:0023052,GO:0023057,GO:0030030,GO:0032501,GO:0032502,GO:0032528,GO:0040011,GO:0042221,GO:0042330,GO:0042493,GO:0042542,GO:0042578,GO:0046677,GO:0047555,GO:0048518,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051606,GO:0051716,GO:0060255,GO:0065007,GO:0071840,GO:0120036,GO:1901700,GO:1902531,GO:1902532 3.1.4.17,3.1.4.35 0.000000000002191 80.0
TLS3_k127_4570796_0 PFAM AAA-4 family protein K02444,K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 446.0
TLS3_k127_4570796_1 PAS fold - - - 0.000000000000000000009737 108.0
TLS3_k127_4573168_0 Beta-lactamase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007626 293.0
TLS3_k127_4573168_1 PFAM PspC domain protein K03973 - - 0.0000000000000000004558 89.0
TLS3_k127_4573168_2 NUDIX domain - - - 0.000000000001765 74.0
TLS3_k127_4573168_3 Beta-lactamase enzyme family - - - 0.0000000000752 68.0
TLS3_k127_4589572_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002364 248.0
TLS3_k127_4589572_1 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000009775 205.0
TLS3_k127_4589572_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000009858 63.0
TLS3_k127_4595698_0 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 297.0
TLS3_k127_4595698_1 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000000001285 122.0
TLS3_k127_4595698_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000002104 102.0
TLS3_k127_4595698_3 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000175 94.0
TLS3_k127_461752_0 Phosphotransferase enzyme family K18844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 357.0
TLS3_k127_461752_1 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 - 2.4.2.22 0.00000000000000000000000000000000000000000000000000000002905 201.0
TLS3_k127_461752_2 Belongs to the FPP GGPP synthase family K00805 - 2.5.1.30 0.00000000000000000000000000000000000000000000000004481 190.0
TLS3_k127_461752_3 Coenzyme A transferase K01028,K01039 - 2.8.3.12,2.8.3.5 0.00000000000000000000000000000000000000000005164 168.0
TLS3_k127_4626194_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975,K01214 - 2.7.7.27,3.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 546.0
TLS3_k127_4626194_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 512.0
TLS3_k127_4626194_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000001142 207.0
TLS3_k127_4626194_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000001174 178.0
TLS3_k127_4626194_4 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.000000000000000000000000000000000000000001346 171.0
TLS3_k127_4626194_5 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000002283 95.0
TLS3_k127_4626194_6 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000001785 91.0
TLS3_k127_4626194_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000007867 57.0
TLS3_k127_463050_0 Serine hydrolase (FSH1) K03928 - 3.1.1.1 0.0000000000000000007257 98.0
TLS3_k127_463050_1 nUDIX hydrolase - - - 0.000000003116 64.0
TLS3_k127_4646032_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 541.0
TLS3_k127_4646032_1 Glycosyltransferase WbsX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000925 256.0
TLS3_k127_4646032_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000001205 153.0
TLS3_k127_4646032_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000005305 154.0
TLS3_k127_4646032_4 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000004225 113.0
TLS3_k127_4646032_5 Protein conserved in bacteria K09796 - - 0.00000000000000000000009298 104.0
TLS3_k127_4646032_6 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000006408 94.0
TLS3_k127_4646032_7 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000007213 83.0
TLS3_k127_4646032_8 PFAM Peptidoglycan-binding LysM - - - 0.000002957 60.0
TLS3_k127_4649356_0 Fibronectin type III-like domain K05349 - 3.2.1.21 3.744e-285 892.0
TLS3_k127_4649356_1 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 501.0
TLS3_k127_4649356_2 WD-40 repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000001215 259.0
TLS3_k127_4649356_3 PFAM glycoside hydrolase family 3 K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000003593 169.0
TLS3_k127_4649540_0 DEAD DEAH box helicase domain protein K06877 - - 7.523e-207 666.0
TLS3_k127_4675980_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K13774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 323.0
TLS3_k127_4675980_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000007274 222.0
TLS3_k127_4675980_2 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000006058 208.0
TLS3_k127_4675980_3 PhoQ Sensor K07682 GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000002975 165.0
TLS3_k127_4675980_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000002237 65.0
TLS3_k127_4675980_5 NUDIX domain - - - 0.00005266 52.0
TLS3_k127_4678383_0 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000004188 169.0
TLS3_k127_4678383_1 integral membrane protein - - - 0.000000000000000000000000000000000004066 153.0
TLS3_k127_4678383_2 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000005805 134.0
TLS3_k127_4678383_3 PFAM Cyclic nucleotide-binding K01420,K21563 - - 0.0000000000000009585 85.0
TLS3_k127_4682945_0 glycosyltransferase 36 associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 582.0
TLS3_k127_4701022_0 Cytochrome c bacterial - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 581.0
TLS3_k127_4701022_1 PFAM NAD dependent epimerase dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 503.0
TLS3_k127_4701022_2 ethanolamine kinase activity K07251,K18844 - 2.7.1.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000004675 269.0
TLS3_k127_4701022_3 Nucleoside H+ symporter K05820 - - 0.0000000000000000000000000000000000000000000000000000000000002567 228.0
TLS3_k127_4701022_4 calcium- and calmodulin-responsive adenylate cyclase activity K07260 - 3.4.17.14 0.00000000000000000000000000000000000000000000000000000000009907 222.0
TLS3_k127_4701022_5 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000003577 108.0
TLS3_k127_4701022_6 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000001261 72.0
TLS3_k127_4714498_0 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 458.0
TLS3_k127_4714498_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 405.0
TLS3_k127_4714498_2 PFAM ABC transporter related K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 324.0
TLS3_k127_4718237_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 591.0
TLS3_k127_4718237_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 316.0
TLS3_k127_4718237_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 293.0
TLS3_k127_4718237_3 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.0000000000000000000000000000000000000000000000000000000003154 208.0
TLS3_k127_4718237_4 PFAM secretion protein HlyD family protein K02005 - - 0.0000000000000000000000000000000000000001393 169.0
TLS3_k127_4718237_5 Two component transcriptional regulator, winged helix family K07658 - - 0.00000000000000000000000000000000005569 136.0
TLS3_k127_4718237_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000132 132.0
TLS3_k127_4726976_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 429.0
TLS3_k127_4726976_1 cAMP-dependent protein kinase regulatory subunit K04739 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005952,GO:0019899,GO:0019900,GO:0019901,GO:0032991,GO:0034236,GO:0042802,GO:0044424,GO:0044464,GO:0051018 - 0.0000000007934 72.0
TLS3_k127_4726976_2 -acetyltransferase - - - 0.000377 53.0
TLS3_k127_4727150_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 519.0
TLS3_k127_4727150_1 PFAM amidinotransferase K01482 - 3.5.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 397.0
TLS3_k127_4727150_2 ABC transporter K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 308.0
TLS3_k127_4727150_3 PFAM Rieske 2Fe-2S domain protein K00479,K00499,K05708 - 1.14.12.19,1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000003792 264.0
TLS3_k127_4727150_4 COG0765 ABC-type amino acid transport system permease component K02029,K10009,K16962 - - 0.0000000000000000000000000000000000000000000000000000000000000005634 229.0
TLS3_k127_4727150_5 amino acid transport K02030 - - 0.0000000000000000000000000000000000000000000000000000000000005783 220.0
TLS3_k127_4727150_6 TIGRFAM Addiction module toxin, RelE StbE - - - 0.000000000000000000000000000000001264 131.0
TLS3_k127_4727150_7 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000004825 106.0
TLS3_k127_4727150_8 Protein of unknown function (DUF664) - - - 0.000000000005411 72.0
TLS3_k127_4728705_0 Glycogen debranching enzyme N terminal - - - 5.532e-281 878.0
TLS3_k127_4728705_1 D-gluconate metabolic process K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 385.0
TLS3_k127_4728705_2 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 348.0
TLS3_k127_4728705_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000313 246.0
TLS3_k127_4728705_4 cAMP-dependent protein kinase regulatory subunit K04739 GO:0000003,GO:0000166,GO:0000228,GO:0000785,GO:0000790,GO:0001932,GO:0001933,GO:0002831,GO:0002832,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005886,GO:0005952,GO:0006469,GO:0006950,GO:0006979,GO:0007154,GO:0008104,GO:0008150,GO:0008277,GO:0008603,GO:0009266,GO:0009267,GO:0009405,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009653,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0009991,GO:0010563,GO:0010570,GO:0010605,GO:0010639,GO:0010646,GO:0010648,GO:0016020,GO:0017076,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019887,GO:0019954,GO:0022603,GO:0023051,GO:0023057,GO:0030154,GO:0030234,GO:0030291,GO:0030435,GO:0030436,GO:0030447,GO:0030448,GO:0030551,GO:0030552,GO:0030554,GO:0031279,GO:0031281,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031981,GO:0032101,GO:0032102,GO:0032104,GO:0032105,GO:0032107,GO:0032108,GO:0032268,GO:0032269,GO:0032386,GO:0032388,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032880,GO:0032991,GO:0033036,GO:0033043,GO:0033157,GO:0033554,GO:0033673,GO:0034305,GO:0034599,GO:0034605,GO:0034613,GO:0036094,GO:0036170,GO:0036180,GO:0040007,GO:0040008,GO:0042173,GO:0042221,GO:0042325,GO:0042326,GO:0042594,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043549,GO:0043934,GO:0043936,GO:0043937,GO:0043938,GO:0043943,GO:0043945,GO:0043949,GO:0043951,GO:0044092,GO:0044093,GO:0044182,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0045595,GO:0045597,GO:0045744,GO:0045761,GO:0045762,GO:0045786,GO:0045859,GO:0045881,GO:0045926,GO:0045936,GO:0046578,GO:0046580,GO:0046822,GO:0046824,GO:0046825,GO:0046827,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051056,GO:0051058,GO:0051094,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051246,GO:0051248,GO:0051338,GO:0051339,GO:0051348,GO:0051349,GO:0051445,GO:0051447,GO:0051641,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051784,GO:0060255,GO:0060258,GO:0060341,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070727,GO:0070887,GO:0071496,GO:0071900,GO:0071901,GO:0071944,GO:0080090,GO:0080134,GO:0090087,GO:0090316,GO:0097159,GO:0097271,GO:0097367,GO:0098772,GO:0106070,GO:0106072,GO:0110033,GO:0110034,GO:1900428,GO:1900429,GO:1900434,GO:1900435,GO:1900443,GO:1900444,GO:1901265,GO:1901363,GO:1902531,GO:1902532,GO:1902659,GO:1902660,GO:1903664,GO:1903666,GO:1903827,GO:1903829,GO:1904951,GO:2000241,GO:2000242,GO:2000479,GO:2000480 - 0.000000000000000000000000007017 120.0
TLS3_k127_4732559_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 1.367e-203 644.0
TLS3_k127_4732559_1 Glycine D-amino acid oxidase (deaminating) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 319.0
TLS3_k127_4732559_2 Cupin domain - - - 0.000001691 53.0
TLS3_k127_4737617_0 Dehydrogenase K08322 - 1.1.1.380 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 329.0
TLS3_k127_4737617_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000004864 236.0
TLS3_k127_4737617_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000001405 205.0
TLS3_k127_4737617_3 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.00000000000000000000000000000000000000006623 160.0
TLS3_k127_4737617_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000001979 111.0
TLS3_k127_4737617_5 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000006425 109.0
TLS3_k127_4737617_6 Antibiotic biosynthesis monooxygenase - - - 0.00000000000003265 76.0
TLS3_k127_4737617_7 - - - - 0.0000000002574 64.0
TLS3_k127_4738860_0 methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000002277 207.0
TLS3_k127_4738860_1 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.0000000000000000000000000000000000000000000000000000000009907 208.0
TLS3_k127_4738860_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000001731 201.0
TLS3_k127_4738860_3 - - - - 0.0000000000000000000000000000000000000000004911 161.0
TLS3_k127_4738860_4 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000003531 144.0
TLS3_k127_4738860_5 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000001056 106.0
TLS3_k127_4738860_6 dTDP biosynthetic process K00560,K00943 - 2.1.1.45,2.7.4.9 0.00000000000000000007665 100.0
TLS3_k127_4738860_7 - - - - 0.000000000007303 68.0
TLS3_k127_4738860_8 AAA domain K07028 - - 0.00001434 48.0
TLS3_k127_4738860_9 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00003522 46.0
TLS3_k127_4752409_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009747 346.0
TLS3_k127_4752409_1 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000002909 242.0
TLS3_k127_4752409_2 amino acid-binding ACT domain protein K04767 - - 0.00000000000000000000000000000000007983 136.0
TLS3_k127_4752862_0 Domain of unknown function (DUF4040) K05559,K05565 - - 1.3e-285 906.0
TLS3_k127_4752862_1 Proton-conducting membrane transporter K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 586.0
TLS3_k127_4752862_2 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05560,K05567 - - 0.00000000000000000000000000000002683 129.0
TLS3_k127_4752862_3 Belongs to the UPF0312 family - - - 0.0000000000000000000005676 98.0
TLS3_k127_4756170_0 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001079 250.0
TLS3_k127_4756170_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.0000000000000000000000000000000000000000000000000000000000225 213.0
TLS3_k127_4756170_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000005746 100.0
TLS3_k127_47843_0 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000002193 196.0
TLS3_k127_47843_1 oligosaccharyl transferase activity - - - 0.000000000000000000000000003267 126.0
TLS3_k127_47843_2 Histidine kinase K07642 - 2.7.13.3 0.00001406 53.0
TLS3_k127_4788847_0 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 475.0
TLS3_k127_4788847_1 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 349.0
TLS3_k127_4788847_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006599 278.0
TLS3_k127_4788847_3 Belongs to the MIP aquaporin (TC 1.A.8) family K02440,K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000005802 233.0
TLS3_k127_4794960_0 PFAM Insertion element protein K07488 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 291.0
TLS3_k127_4794960_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008636 274.0
TLS3_k127_4794960_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000001091 232.0
TLS3_k127_4794960_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000004016 182.0
TLS3_k127_4794960_4 ISXO2-like transposase domain - - - 0.0000000000000000000000000000000000000000003275 161.0
TLS3_k127_4794960_5 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K03320,K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000003568 98.0
TLS3_k127_4794960_6 response regulator - - - 0.000000000000000000114 93.0
TLS3_k127_4794960_7 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000171 87.0
TLS3_k127_4804250_0 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005303 265.0
TLS3_k127_4804250_1 monovalent cation:proton antiporter activity K05571 - - 0.00000000000000000000000000006993 118.0
TLS3_k127_4804250_2 multisubunit Na H antiporter MnhE subunit K05569 - - 0.0000000000000000000000003194 110.0
TLS3_k127_4804250_4 Amidohydrolase family K01464 - 3.5.2.2 0.00000001519 59.0
TLS3_k127_4804800_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.435e-238 752.0
TLS3_k127_4804800_1 Protein of unknown function (DUF3179) - - - 0.000000000000000000000000000000000000000000000005626 181.0
TLS3_k127_4810659_0 Enoyl-(Acyl carrier protein) reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 290.0
TLS3_k127_4810659_1 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 289.0
TLS3_k127_4810659_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000009413 195.0
TLS3_k127_4810659_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000008028 167.0
TLS3_k127_4810659_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.000000000000000000000000000000000001629 143.0
TLS3_k127_4810659_5 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.0000000000000000000000000000000002139 134.0
TLS3_k127_4810659_6 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000001395 78.0
TLS3_k127_4810659_7 Asp23 family, cell envelope-related function - - - 0.0000000000004319 74.0
TLS3_k127_4810659_8 Mutator MutT protein K03574 - 3.6.1.55 0.0000002374 58.0
TLS3_k127_4812162_0 deaminase activity K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 390.0
TLS3_k127_4812162_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000207 271.0
TLS3_k127_4812162_2 Phosphotransferase enzyme family - - - 0.0002962 49.0
TLS3_k127_4812695_0 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000001344 267.0
TLS3_k127_4812695_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000001165 258.0
TLS3_k127_4812695_2 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000001887 58.0
TLS3_k127_4819844_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000003454 239.0
TLS3_k127_4819844_1 Protein of unknown function (DUF2723) K14340 - - 0.0000000000000000000000000001048 135.0
TLS3_k127_4819844_2 Membrane - - - 0.000000000227 75.0
TLS3_k127_4832699_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007798 289.0
TLS3_k127_4832699_1 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000127 195.0
TLS3_k127_4832699_2 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000001549 164.0
TLS3_k127_4832699_3 ComEA protein K02237 - - 0.0000000000000000000000000000001104 133.0
TLS3_k127_4832699_4 Protein of unknown function (DUF3467) - - - 0.0000000000000000004516 91.0
TLS3_k127_4838892_0 Adenylosuccinate lyase C-terminus K01857 - 5.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 354.0
TLS3_k127_4838892_1 Domain of unknown function (DUF3368) K07066 - - 0.00000000000000000000000000000000000000000002647 166.0
TLS3_k127_4838892_2 Uncharacterised protein family (UPF0175) - - - 0.000000000000000000000002269 106.0
TLS3_k127_4838892_3 PFAM adenylate cyclase K05873 - 4.6.1.1 0.00001581 48.0
TLS3_k127_484007_0 hydrolase, family 3 K05349 - 3.2.1.21 7.929e-227 725.0
TLS3_k127_484007_1 periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001055 281.0
TLS3_k127_484007_2 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.0000001315 59.0
TLS3_k127_486876_0 glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000002659 222.0
TLS3_k127_486876_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000003014 190.0
TLS3_k127_488437_0 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.0000000000000000000000000000000002079 144.0
TLS3_k127_488437_1 PFAM ABC transporter related K01990 - - 0.000000000000000000606 90.0
TLS3_k127_488437_2 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.0001281 53.0
TLS3_k127_4888884_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 556.0
TLS3_k127_4888884_1 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000001099 231.0
TLS3_k127_4888884_2 Xanthine dehydrogenase, molybdenum binding subunit - - - 0.0000000000000000000000000001308 118.0
TLS3_k127_492802_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 602.0
TLS3_k127_492802_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 462.0
TLS3_k127_492802_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 316.0
TLS3_k127_492802_3 Phosphoribosyl transferase domain K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000001037 223.0
TLS3_k127_492802_4 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000000000000000000000000007938 186.0
TLS3_k127_4931779_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 294.0
TLS3_k127_4931779_1 Pyridoxamine 5'-phosphate oxidase K09979 - - 0.00000000000000000000000000000000000007849 146.0
TLS3_k127_4931779_2 OST-HTH/LOTUS domain - - - 0.0000000000000000000003949 109.0
TLS3_k127_4931779_3 - - - - 0.000000000000000000001731 102.0
TLS3_k127_4931779_4 Flagellar filament outer layer protein Flaa - - - 0.0000000000000000001637 103.0
TLS3_k127_4931779_6 Flp Fap pilin component K02651 - - 0.00000375 55.0
TLS3_k127_4937201_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 621.0
TLS3_k127_4937201_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 0.000000000000000000000000000000000000000000000000001607 187.0
TLS3_k127_4939354_0 isochorismatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004848 280.0
TLS3_k127_4939354_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000003272 249.0
TLS3_k127_4939354_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000002866 189.0
TLS3_k127_4939354_4 Acetyltransferase (GNAT) family - - - 0.000000000000003221 81.0
TLS3_k127_4939354_5 oxidoreductase activity - - - 0.00003595 54.0
TLS3_k127_4941991_0 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K13668 - 2.4.1.346 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 607.0
TLS3_k127_4941991_1 Alkaline and neutral invertase - - - 0.00000000000000000000000000000000000000000000000000000000000000001603 224.0
TLS3_k127_4951372_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 391.0
TLS3_k127_4951372_1 MgtC family K07507 - - 0.000000000000000000000000000000006967 132.0
TLS3_k127_4951372_2 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000009841 134.0
TLS3_k127_4951372_3 - - - - 0.00000000000000000006549 97.0
TLS3_k127_4951372_4 PFAM Methyltransferase type 12 - - - 0.00000000000000001478 83.0
TLS3_k127_4951372_5 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0003485 46.0
TLS3_k127_4953904_0 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003684 282.0
TLS3_k127_4953904_1 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.00000000000000000000000000000000000000000000000000000000000002061 226.0
TLS3_k127_4953904_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000001322 87.0
TLS3_k127_4960725_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.959e-203 658.0
TLS3_k127_4960725_1 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000001239 162.0
TLS3_k127_4960725_2 DAK2 domain fusion protein YloV K07030 - - 0.000000000000001822 78.0
TLS3_k127_4972676_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 480.0
TLS3_k127_4972676_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 417.0
TLS3_k127_4972676_2 Penicillin-binding Protein dimerisation domain K03587,K08384 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 418.0
TLS3_k127_4972676_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 339.0
TLS3_k127_4972676_4 Belongs to the SEDS family K05837 - - 0.000000001462 64.0
TLS3_k127_5000593_0 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 293.0
TLS3_k127_5000593_1 PFAM aminotransferase class V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001025 273.0
TLS3_k127_5000593_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025,K20866 - 3.1.3.10 0.00000000000000000000000000000001689 137.0
TLS3_k127_5000593_3 sh3 domain protein K01227,K03642 - 3.2.1.96 0.000000000000002457 88.0
TLS3_k127_5004747_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 565.0
TLS3_k127_5004747_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 498.0
TLS3_k127_5004747_2 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000000000001423 168.0
TLS3_k127_5016956_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000153 236.0
TLS3_k127_5016956_1 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000001553 118.0
TLS3_k127_5016956_2 - - - - 0.00000000000000000000003298 108.0
TLS3_k127_5016956_3 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000001584 89.0
TLS3_k127_5016956_4 response regulator - - - 0.000000000004644 73.0
TLS3_k127_5028050_0 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 518.0
TLS3_k127_5028050_1 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000006766 235.0
TLS3_k127_5028050_2 Aminoacyl-tRNA editing domain - - - 0.0000003572 56.0
TLS3_k127_5049947_0 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002698 265.0
TLS3_k127_5049947_1 Helix-turn-helix domain - - - 0.0000000000002365 78.0
TLS3_k127_5052738_0 Bacterial extracellular solute-binding protein - - - 3.69e-219 687.0
TLS3_k127_5052738_1 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 539.0
TLS3_k127_5052738_2 - - - - 0.0000000000000000000000000000004289 130.0
TLS3_k127_505806_0 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000001458 183.0
TLS3_k127_505806_1 SMART PAS domain containing protein - - - 0.0000000000000001095 92.0
TLS3_k127_505806_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.0005611 51.0
TLS3_k127_5062679_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 309.0
TLS3_k127_5062679_1 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000003819 177.0
TLS3_k127_5062679_2 Belongs to the UPF0102 family K07460 - - 0.0000000000000005579 79.0
TLS3_k127_5062679_3 - - - - 0.000000191 59.0
TLS3_k127_5075775_0 - - - - 0.0000000000000000000000000233 122.0
TLS3_k127_5075775_1 Tetratricopeptide repeat - - - 0.000000000000000001451 102.0
TLS3_k127_5076644_0 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006805 615.0
TLS3_k127_5076644_1 Transcriptional regulator K05799 - - 0.000000000000000000000000000000000000000000000000000000000000002729 224.0
TLS3_k127_5076644_2 extracellular matrix structural constituent - - - 0.000000001291 61.0
TLS3_k127_5082107_0 Tex-like protein N-terminal domain K06959 - - 1.439e-280 878.0
TLS3_k127_5082107_1 COG1233 Phytoene dehydrogenase and related K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 1.479e-242 757.0
TLS3_k127_5082107_2 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 350.0
TLS3_k127_5099680_0 Bacterial extracellular solute-binding protein K02064 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 424.0
TLS3_k127_5099680_1 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001614 281.0
TLS3_k127_5099680_2 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000006816 176.0
TLS3_k127_5099680_3 PFAM Thiamin pyrophosphokinase, catalytic region K00949 - 2.7.6.2 0.0000000000000000000000000000000000000001028 158.0
TLS3_k127_5099680_4 proteolysis - - - 0.00000000000000000000000000000002932 139.0
TLS3_k127_5099680_5 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000121 73.0
TLS3_k127_5102145_0 cellobiose phosphorylase K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 2.061e-256 830.0
TLS3_k127_5102145_1 LUD domain K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007577 264.0
TLS3_k127_5102145_2 Universal stress protein - - - 0.0000000000000000000000000000000000000000002895 171.0
TLS3_k127_5102145_3 LUD domain K00782,K18929 - - 0.00000000000000000000000005883 116.0
TLS3_k127_5102145_4 - - - - 0.000000000000000000001573 103.0
TLS3_k127_5102145_5 Type III secretion system lipoprotein chaperone (YscW) K09914 - - 0.000002636 53.0
TLS3_k127_5115097_0 PFAM Uncharacterised protein family UPF0182 K09118 - - 1.224e-233 755.0
TLS3_k127_5115097_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 4.304e-205 684.0
TLS3_k127_5115097_2 Homocysteine S-methyltransferase K00544,K00548 - 2.1.1.13,2.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 320.0
TLS3_k127_5115097_3 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002698 261.0
TLS3_k127_5115097_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000001841 259.0
TLS3_k127_5115097_5 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000000000000000007256 190.0
TLS3_k127_5115097_6 NUDIX domain - - - 0.000000000000000009435 92.0
TLS3_k127_5115097_7 phosphatase activity K01560,K07025 - 3.8.1.2 0.000000000000007388 81.0
TLS3_k127_5115097_8 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00007506 54.0
TLS3_k127_5117194_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 377.0
TLS3_k127_5117194_1 HD domain - - - 0.0000000000000000000000000000006426 138.0
TLS3_k127_5121983_0 PFAM FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 523.0
TLS3_k127_5121983_1 Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 367.0
TLS3_k127_5121983_10 Protein of unknown function DUF126 K09128 - - 0.00000000000001737 87.0
TLS3_k127_5121983_11 Belongs to the P(II) protein family - - - 0.000000004155 62.0
TLS3_k127_5121983_12 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00009892 51.0
TLS3_k127_5121983_2 SMART Nucleotide binding protein, PINc - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 361.0
TLS3_k127_5121983_3 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 310.0
TLS3_k127_5121983_4 NmrA-like family K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 300.0
TLS3_k127_5121983_5 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000001144 230.0
TLS3_k127_5121983_6 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000000000000000001824 192.0
TLS3_k127_5121983_7 Sodium/hydrogen exchanger family K03316 - - 0.00000000000000000000000000000000000000000000004846 178.0
TLS3_k127_5121983_8 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000001424 186.0
TLS3_k127_5123668_0 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 374.0
TLS3_k127_5123668_1 PFAM PSP1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003415 254.0
TLS3_k127_5123668_2 TIGRFAM metal dependent phophohydrolase - - - 0.0000000000000000000000000000000000000000000000000003572 192.0
TLS3_k127_5123668_3 PFAM RNA binding S1 domain protein - - - 0.000000000000000000000000000000000000000004982 164.0
TLS3_k127_5156964_0 HEAT repeats - - - 0.00000000000000000000000000000000000000000000001279 184.0
TLS3_k127_5156964_1 PFAM Auxin Efflux Carrier K07088 - - 0.0000000000000000000000000000000000004146 151.0
TLS3_k127_5156964_2 Peptidase MA superfamily - - - 0.0000000000000000000000000000000005347 146.0
TLS3_k127_5156964_3 SnoaL-like domain K01822 - 5.3.3.1 0.0000000000000000000002879 98.0
TLS3_k127_5162958_0 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003166 299.0
TLS3_k127_5162958_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000007217 156.0
TLS3_k127_5162958_2 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000533 54.0
TLS3_k127_5163494_0 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 607.0
TLS3_k127_5163494_1 Creatinase/Prolidase N-terminal domain K01262,K01271,K08326 GO:0003674,GO:0003824,GO:0004177,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002168 283.0
TLS3_k127_5163494_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000001664 237.0
TLS3_k127_5168149_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001031 252.0
TLS3_k127_5168149_1 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001477 249.0
TLS3_k127_5168149_2 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000003117 233.0
TLS3_k127_5168149_3 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000006624 177.0
TLS3_k127_5168149_4 - - - - 0.0000000006675 66.0
TLS3_k127_5168149_5 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00001178 57.0
TLS3_k127_5171216_0 trisaccharide binding - - - 2.517e-231 743.0
TLS3_k127_5171216_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004389 262.0
TLS3_k127_5171216_2 alginic acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000001071 197.0
TLS3_k127_5171216_3 Zinc-uptake complex component A periplasmic K02077,K09818 - - 0.000000000000000000000000000000000000000000000000000001632 205.0
TLS3_k127_5175460_0 elongation factor Tu domain 2 protein K02355 - - 2.732e-215 688.0
TLS3_k127_5175460_1 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 549.0
TLS3_k127_5175460_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 456.0
TLS3_k127_5175460_3 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003967 290.0
TLS3_k127_5175460_4 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001697 234.0
TLS3_k127_5175460_5 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000004841 220.0
TLS3_k127_5175460_6 PFAM Fe-S metabolism associated SufE K02426 - - 0.000000000000000000000000000000000000000000008028 167.0
TLS3_k127_5175460_7 Low molecular weight phosphotyrosine protein phosphatase K03892 - - 0.0000001242 59.0
TLS3_k127_5175460_8 - - - - 0.000001818 59.0
TLS3_k127_517594_0 carbohydrate transport K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 584.0
TLS3_k127_517594_1 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007014 524.0
TLS3_k127_517594_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 403.0
TLS3_k127_517594_3 protein conserved in bacteria K09778 - - 0.000000000000000000000003817 109.0
TLS3_k127_517594_4 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000002143 106.0
TLS3_k127_517594_5 Glycosyl hydrolase family 65, C-terminal domain K04844,K05342,K10231 - 2.4.1.230,2.4.1.64 0.00000000000002527 73.0
TLS3_k127_517594_6 Protein of unknown function, DUF624 - - - 0.0005682 49.0
TLS3_k127_5177373_0 ATPase AAA-2 domain protein K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 560.0
TLS3_k127_5177373_1 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003197 295.0
TLS3_k127_5177373_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000959 67.0
TLS3_k127_5177373_3 Lysin motif - - - 0.0000001356 58.0
TLS3_k127_5189302_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 408.0
TLS3_k127_5189302_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 289.0
TLS3_k127_5189302_2 - - - - 0.00000000000000000000000004682 108.0
TLS3_k127_5210988_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 1.737e-218 702.0
TLS3_k127_5210988_1 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0000000000000000000000000000000000000000000000000005407 186.0
TLS3_k127_5210988_2 LysM domain - - - 0.0000000000000000000000000000000000000282 147.0
TLS3_k127_5252426_0 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 362.0
TLS3_k127_5252426_1 PFAM YhhN family protein - - - 0.000000000000000000000000000000000000000000000000000000006101 207.0
TLS3_k127_5252426_2 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.0000000005405 62.0
TLS3_k127_5253579_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 3.49e-199 628.0
TLS3_k127_5253579_1 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000698 211.0
TLS3_k127_5253579_2 phosphatidylcholine synthase activity K01004,K17103 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24,2.7.8.8 0.0000000000000000000000000000000000000000000000000000006471 200.0
TLS3_k127_5266563_0 Belongs to the 3-oxoacid CoA-transferase family K01027 - 2.8.3.5 1.808e-200 629.0
TLS3_k127_5266563_1 PFAM Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000004537 166.0
TLS3_k127_5270037_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000007725 259.0
TLS3_k127_5270037_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000004087 211.0
TLS3_k127_5270037_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000008218 171.0
TLS3_k127_5270037_3 - - - - 0.000000000000000004018 96.0
TLS3_k127_5284468_0 DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 439.0
TLS3_k127_5284468_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 390.0
TLS3_k127_5284468_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 346.0
TLS3_k127_5284468_3 DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000309 234.0
TLS3_k127_5285805_0 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 411.0
TLS3_k127_5285805_1 Pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000005604 199.0
TLS3_k127_5285805_2 EamA-like transporter family - - - 0.00000000000000000000000000007636 121.0
TLS3_k127_5285805_3 Domain of unknown function (DUF1508) - - - 0.0000000000000000000000000004197 117.0
TLS3_k127_5298514_0 esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 347.0
TLS3_k127_5298514_1 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 326.0
TLS3_k127_5298514_2 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008475 279.0
TLS3_k127_5298514_3 PFAM DegV family protein - - - 0.000000000000000000000000000000000000000000000000000000000000002269 229.0
TLS3_k127_5298984_0 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.000000000000000000000000000000000000000000006919 180.0
TLS3_k127_5298984_1 PFAM homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000002782 72.0
TLS3_k127_5300506_0 Belongs to the glycosyl hydrolase family 6 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 454.0
TLS3_k127_5300506_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001747 265.0
TLS3_k127_5300506_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001502 239.0
TLS3_k127_5300506_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000007204 199.0
TLS3_k127_5300506_4 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000002585 166.0
TLS3_k127_5300677_0 PFAM binding-protein-dependent transport systems inner membrane component K15772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 312.0
TLS3_k127_5300677_1 PFAM binding-protein-dependent transport systems inner membrane component K10109 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 288.0
TLS3_k127_5300677_2 PFAM glycosyl hydrolase 53 domain protein K01224 - 3.2.1.89 0.000000000000000000000000000000000000000000000001091 183.0
TLS3_k127_5308843_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 518.0
TLS3_k127_5308843_1 cytokinin biosynthetic process K06966 - 3.2.2.10 0.00000000000000000000000000000000000000003611 158.0
TLS3_k127_5308843_2 PFAM aspartate glutamate uridylate kinase K06981 - 2.7.4.26 0.00000000000000000000000000000000000002057 147.0
TLS3_k127_5308843_3 Alpha beta hydrolase - - - 0.0000000000000000000000002755 117.0
TLS3_k127_5308843_4 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000009419 98.0
TLS3_k127_5308843_5 Multisubunit Na H antiporter MnhC subunit K00340,K05567 - 1.6.5.3 0.0000000000000000000518 94.0
TLS3_k127_5318969_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K08070 - 1.3.1.74,3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 327.0
TLS3_k127_5318969_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000005113 248.0
TLS3_k127_5318969_2 PFAM Thioredoxin domain K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000003847 229.0
TLS3_k127_5318969_3 Domain of unknown function (DUF4872) - - - 0.000000000000000000000000000000000000000000000001626 182.0
TLS3_k127_5318969_4 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K02056,K13924 - 2.1.1.80,3.1.1.61,3.6.3.17 0.0000000000000000000003354 97.0
TLS3_k127_5344798_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 399.0
TLS3_k127_5344798_1 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000006017 209.0
TLS3_k127_5355124_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 407.0
TLS3_k127_5355124_1 Galactose oxidase, central domain - - - 0.0000000000000000000000000000000000000000000007712 183.0
TLS3_k127_5355124_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 0.00001053 49.0
TLS3_k127_5369452_0 choline dehydrogenase activity K03333 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016614,GO:0016899,GO:0016995,GO:0044419,GO:0051704,GO:0055114 1.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008351 612.0
TLS3_k127_5369452_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 454.0
TLS3_k127_5369452_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 420.0
TLS3_k127_5369452_3 Belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 398.0
TLS3_k127_5369452_4 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004716 287.0
TLS3_k127_5369452_5 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000003129 218.0
TLS3_k127_5369452_6 Two component transcriptional regulator, winged helix family K07667 - - 0.000000000000000000000000000000000000000000000001239 184.0
TLS3_k127_5369452_7 Belongs to the ParB family K03497 - - 0.0000000000000000000000000006464 128.0
TLS3_k127_5369452_8 Periplasmic component of the Tol biopolymer transport system - - - 0.000000001132 70.0
TLS3_k127_5371325_0 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008398 522.0
TLS3_k127_5371325_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 473.0
TLS3_k127_5371325_2 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 377.0
TLS3_k127_5371325_3 histidine kinase A domain protein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008236 366.0
TLS3_k127_5371325_4 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.0000000000000000000000000000000000000000000000000000000000008864 214.0
TLS3_k127_5371325_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000006545 116.0
TLS3_k127_5371325_6 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000001222 59.0
TLS3_k127_5375207_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 424.0
TLS3_k127_5375207_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000001504 110.0
TLS3_k127_5376705_0 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 300.0
TLS3_k127_5376705_1 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000000000000000005118 173.0
TLS3_k127_53833_0 PFAM alpha amylase, catalytic K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 589.0
TLS3_k127_53833_1 - - - - 0.000000000000000000000000000000000000000000000000000000000009153 213.0
TLS3_k127_53833_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000002629 177.0
TLS3_k127_53833_3 Aminoacyl-tRNA editing domain K03976 - - 0.0000000000000000000000000000000000001126 148.0
TLS3_k127_53833_4 phosphorelay sensor kinase activity K01768,K02482,K02584,K07673,K10819 - 2.7.13.3,4.6.1.1 0.0000000000000000000000000000001925 137.0
TLS3_k127_53833_6 PFAM response regulator receiver - - - 0.00000001291 61.0
TLS3_k127_5408118_0 cellulase activity K01183 - 3.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 370.0
TLS3_k127_5408118_1 Bacterial transcriptional activator domain - - - 0.00000000000000000003498 102.0
TLS3_k127_5408118_2 TIGRFAM transposase, IS605 OrfB family K07496 - - 0.00000000000000305 77.0
TLS3_k127_5408118_3 Spoiid lytb domain protein K06381 - - 0.0001028 55.0
TLS3_k127_5409395_0 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000000000000000000000000000001327 214.0
TLS3_k127_5409395_1 Domain of unknown function (DUF4380) - - - 0.0000000000000000000000000006125 118.0
TLS3_k127_5409395_2 Endonuclease containing a URI domain K07461 - - 0.000000000000000000000000003725 113.0
TLS3_k127_5409395_3 choline kinase involved in LPS biosynthesis - - - 0.00000003473 65.0
TLS3_k127_5409395_4 ABC-2 family transporter protein K01992 - - 0.0000003161 54.0
TLS3_k127_5413499_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 389.0
TLS3_k127_5413499_1 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 360.0
TLS3_k127_5413499_2 PhoQ Sensor K07682 GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 314.0
TLS3_k127_5413499_3 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 300.0
TLS3_k127_5413499_4 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000008299 252.0
TLS3_k127_5413499_5 Transcriptional regulator, Crp Fnr family K01420,K10914 - - 0.00000000000000000000000000000000000000000000000000001382 197.0
TLS3_k127_5413499_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000002762 122.0
TLS3_k127_5414039_0 PFAM Glycoside hydrolase, clan GH-D K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 573.0
TLS3_k127_5414039_1 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000001284 185.0
TLS3_k127_5414039_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000003789 137.0
TLS3_k127_5414039_3 - - - - 0.000000000000000000000000000000004241 131.0
TLS3_k127_5414039_4 gnat family - - - 0.00001114 53.0
TLS3_k127_5427021_0 ABC-type sugar transport system periplasmic component K10559 - - 2.004e-295 926.0
TLS3_k127_5427021_1 Domain of unknown function (DUF4037) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 426.0
TLS3_k127_5427021_2 Belongs to the binding-protein-dependent transport system permease family K10561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 410.0
TLS3_k127_5427021_3 Belongs to the binding-protein-dependent transport system permease family K10560 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 415.0
TLS3_k127_5427021_4 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10562 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009584 396.0
TLS3_k127_5429519_0 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000008597 181.0
TLS3_k127_5429519_1 - - - - 0.000000000000000000000000000000000000000000000002842 177.0
TLS3_k127_5429519_2 - - - - 0.0000000000000000000000001487 109.0
TLS3_k127_5429519_3 PFAM SMC domain protein K03546 - - 0.000005539 52.0
TLS3_k127_5429519_4 Protein of unknown function (DUF456) K09793 - - 0.0005911 49.0
TLS3_k127_543238_0 Transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001129 270.0
TLS3_k127_543238_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000543 194.0
TLS3_k127_5433266_0 Belongs to the bacterial solute-binding protein 9 family K11707 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 410.0
TLS3_k127_5433266_1 ATPases associated with a variety of cellular activities K09817,K11710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 362.0
TLS3_k127_5433266_2 ABC 3 transport family K11708 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000005088 102.0
TLS3_k127_5433266_3 helix_turn_helix, mercury resistance - - - 0.00000000000000005117 91.0
TLS3_k127_5435195_0 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 413.0
TLS3_k127_5435195_1 Myo-inositol-1-phosphate synthase K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 347.0
TLS3_k127_5435195_2 Xylose isomerase-like TIM barrel K18910 - 5.1.3.30,5.1.3.31 0.000000000000000000000000000000000000000000008775 172.0
TLS3_k127_5446073_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 325.0
TLS3_k127_5446073_1 cell redox homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002743 283.0
TLS3_k127_5446073_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000001837 73.0
TLS3_k127_5446073_3 COG0457 FOG TPR repeat - - - 0.000002415 59.0
TLS3_k127_5450633_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 409.0
TLS3_k127_5450633_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002153 279.0
TLS3_k127_5450633_2 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000002818 202.0
TLS3_k127_5474380_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 313.0
TLS3_k127_5474380_1 PFAM GCN5-related N-acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000002308 172.0
TLS3_k127_5474380_2 peptidase M23 - - - 0.00000000000000000004365 97.0
TLS3_k127_5477161_0 CpXC protein - - - 0.000000000000000000000000000000000000000000000000000000000004757 224.0
TLS3_k127_5477161_1 exodeoxyribonuclease I activity - - - 0.0000000000000000000000000000000000000001423 156.0
TLS3_k127_5477161_2 ABC-type multidrug transport system ATPase component K01990 - - 0.000000006912 59.0
TLS3_k127_5477161_3 Flp Fap pilin component K02651 - - 0.0000008115 52.0
TLS3_k127_548688_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 1.253e-282 893.0
TLS3_k127_5490001_0 Nucleotidyltransferase K09962 - - 0.000000000000000000000000000000000000000000000161 175.0
TLS3_k127_5490001_1 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000001846 170.0
TLS3_k127_5490001_2 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 0.000000000000004266 77.0
TLS3_k127_5490001_3 PFAM luciferase family protein - - - 0.00001448 49.0
TLS3_k127_5502086_0 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.0 1086.0
TLS3_k127_5502086_1 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008504 346.0
TLS3_k127_5502086_2 Type IV pili methyl-accepting chemotaxis transducer N-term K07673 - 2.7.13.3 0.000000000000000000000000000000000000000000004965 185.0
TLS3_k127_5502086_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000004963 138.0
TLS3_k127_5502086_4 diguanylate cyclase - - - 0.00000000000001226 88.0
TLS3_k127_5502507_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 4.45e-297 921.0
TLS3_k127_5502507_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 5.604e-216 682.0
TLS3_k127_5521768_0 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001462 235.0
TLS3_k127_5521768_2 stress-induced mitochondrial fusion K04066,K07037,K17266 - - 0.00006152 53.0
TLS3_k127_5525431_0 PFAM Stage II sporulation E family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003702 229.0
TLS3_k127_5525431_1 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000006818 198.0
TLS3_k127_5525431_2 - - - - 0.000000000000000000000000000000000000007911 149.0
TLS3_k127_5525431_3 Antitoxin Phd_YefM, type II toxin-antitoxin system K19159 - - 0.0000000000000000000000000000000001144 135.0
TLS3_k127_5525431_4 Methyltransferase domain - - - 0.0000000000000000000000000000000001399 141.0
TLS3_k127_5525431_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - 0.000000000000000000000003024 106.0
TLS3_k127_5525431_6 TIGRFAM Addiction module killer protein, HI1419 - - - 0.0000000000000000005554 94.0
TLS3_k127_5542932_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000005469 144.0
TLS3_k127_5542932_1 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.00000000000000000000000001909 118.0
TLS3_k127_5545880_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 487.0
TLS3_k127_555170_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 581.0
TLS3_k127_555170_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 511.0
TLS3_k127_555170_2 transmembrane transport K22044 GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 - 0.0000000000000000000000000000000003418 141.0
TLS3_k127_556220_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 321.0
TLS3_k127_556220_2 Carbamoyl-phosphate synthetase large chain domain protein K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000003464 254.0
TLS3_k127_556220_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000002614 168.0
TLS3_k127_556220_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000001168 60.0
TLS3_k127_5564570_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 8.056e-291 899.0
TLS3_k127_5564570_1 PFAM LysM domain - - - 0.000001974 59.0
TLS3_k127_5564570_2 PFAM Thioredoxin K03671 - - 0.00007729 48.0
TLS3_k127_5583012_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 375.0
TLS3_k127_5583012_1 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 340.0
TLS3_k127_5583012_2 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 324.0
TLS3_k127_5583012_3 Integrin alpha (beta-propellor repeats). - - - 0.0000001697 60.0
TLS3_k127_5591954_0 SMART AAA ATPase K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 359.0
TLS3_k127_5591954_1 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 322.0
TLS3_k127_5591954_2 PFAM thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000000002494 177.0
TLS3_k127_5591954_3 GtrA-like protein - - - 0.00000000000000000000000000000000000003617 150.0
TLS3_k127_5591954_4 PFAM Archaeal ATPase - - - 0.00000000000000000000000000000000007548 156.0
TLS3_k127_5591954_5 O-Antigen ligase - - - 0.00000000000000000000000000895 115.0
TLS3_k127_5591954_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000891 94.0
TLS3_k127_5591954_7 PFAM Archaeal ATPase - - - 0.00000000000005596 84.0
TLS3_k127_5602954_0 cellulase activity K01183 - 3.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 353.0
TLS3_k127_5602954_1 sh3 domain protein K01448,K04771,K08884 - 2.7.11.1,3.4.21.107,3.5.1.28 0.0000000004541 73.0
TLS3_k127_5602954_2 FtsX-like permease family K02004 - - 0.00073 44.0
TLS3_k127_5614597_0 acetolactate synthase K01576,K01652 - 2.2.1.6,4.1.1.7 3.504e-205 653.0
TLS3_k127_5614597_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 454.0
TLS3_k127_5614597_2 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000002833 200.0
TLS3_k127_5614597_3 Purine catabolism regulatory protein-like family K09684 - - 0.0000000000000000000000000000000000000000003498 172.0
TLS3_k127_5618339_0 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009288 409.0
TLS3_k127_5618339_1 Helix-hairpin-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001504 274.0
TLS3_k127_5618339_2 PFAM peptidase S16 lon domain protein - - - 0.000000000000000000000000000000000000000000000004954 175.0
TLS3_k127_5618339_3 AMP binding - - - 0.000000000000000000000000004215 117.0
TLS3_k127_5618339_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000002941 90.0
TLS3_k127_5633617_0 efflux transmembrane transporter activity K02004,K16918 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001582 291.0
TLS3_k127_5633617_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001357 235.0
TLS3_k127_5633617_2 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000000000000005821 127.0
TLS3_k127_5633617_3 Rieske-like [2Fe-2S] domain K15762 - - 0.00000000002168 71.0
TLS3_k127_5633617_4 PFAM Redoxin domain protein - - - 0.00000003237 58.0
TLS3_k127_5634332_0 cellulase activity K01183 - 3.2.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 348.0
TLS3_k127_5634332_1 Cna B domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 366.0
TLS3_k127_5634332_2 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K01227 - 3.2.1.96 0.0000004705 63.0
TLS3_k127_563441_0 YidE YbjL duplication domain protein K07085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 508.0
TLS3_k127_563441_1 SPW repeat - - - 0.000000000000000005583 89.0
TLS3_k127_563441_2 Membrane - - - 0.0000000000000006063 81.0
TLS3_k127_563441_3 PFAM Forkhead-associated protein - - - 0.0000000007832 72.0
TLS3_k127_5647924_0 XdhC Rossmann domain K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 311.0
TLS3_k127_5647924_1 Ecdysteroid kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 306.0
TLS3_k127_565073_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 366.0
TLS3_k127_565073_1 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000005045 203.0
TLS3_k127_565073_2 Predicted membrane protein (DUF2243) - - - 0.00000000000000000000000000000000000008839 142.0
TLS3_k127_5651949_0 FAD dependent oxidoreductase - - - 7.137e-230 725.0
TLS3_k127_5651949_1 COG0714 MoxR-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 344.0
TLS3_k127_5651949_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001015 267.0
TLS3_k127_5651949_3 PhoQ Sensor - - - 0.000000000000000000000000000000000000000007535 171.0
TLS3_k127_5651949_4 Transposase DDE domain - - - 0.0000001226 63.0
TLS3_k127_5666773_0 Aldehyde dehydrogenase (NAD) family protein K13922 - 1.2.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009131 485.0
TLS3_k127_5666773_2 BMC - - - 0.0000000000000000000000000000000001116 140.0
TLS3_k127_5666773_3 AAA domain K02282 - - 0.0000000000000000000000000000000009906 144.0
TLS3_k127_5666773_4 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.00008238 49.0
TLS3_k127_567676_0 Formamidopyrimidine-DNA glycosylase N-terminal domain K05522 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 289.0
TLS3_k127_567676_1 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000007585 226.0
TLS3_k127_567676_2 PFAM DSBA oxidoreductase - - - 0.00000000000000000000000000000000000000000000001277 176.0
TLS3_k127_568700_0 carbohydrate transport K02027,K10117,K11751 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000381 304.0
TLS3_k127_5690707_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 464.0
TLS3_k127_5690707_1 Acetylornithine deacetylase K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 293.0
TLS3_k127_5690707_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000005403 99.0
TLS3_k127_5690944_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 2.67e-216 683.0
TLS3_k127_5690944_1 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000005811 164.0
TLS3_k127_5690944_2 - - - - 0.000000000000000000001827 96.0
TLS3_k127_5690944_3 - - - - 0.0000000004938 63.0
TLS3_k127_5690944_4 ATPase family associated with various cellular activities (AAA) - - - 0.0000000006864 68.0
TLS3_k127_5691326_0 Tetratricopeptide TPR_2 repeat protein - - - 2.169e-263 871.0
TLS3_k127_5691326_1 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000000000000000000000002395 158.0
TLS3_k127_5703940_0 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000007256 195.0
TLS3_k127_5703940_1 PFAM DinB family protein - - - 0.0000000000000000000000000000000000000000000002295 170.0
TLS3_k127_5703940_2 - - - - 0.0000000000000000000000000000000000000000000007072 174.0
TLS3_k127_5703940_3 PFAM DinB family protein - - - 0.0000000000000000000000000000000000000002165 154.0
TLS3_k127_5703940_4 Protein of unknown function (DUF1706) - - - 0.0000000000000000000000000000000000001221 148.0
TLS3_k127_5703940_5 Domain of unknown function (DUF4111) - - - 0.0000000000000000000000000000000878 134.0
TLS3_k127_5703940_6 Domain of unknown function (DUF4385) - - - 0.000000000000000000000001559 104.0
TLS3_k127_570593_0 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 320.0
TLS3_k127_570593_1 ABC-3 protein K09819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 299.0
TLS3_k127_570593_2 PFAM ABC transporter related K09820,K11710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 288.0
TLS3_k127_570593_3 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000001573 249.0
TLS3_k127_570593_4 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000006996 244.0
TLS3_k127_570593_5 permease - - - 0.000000000000000000000000000000000000124 153.0
TLS3_k127_570593_6 Belongs to the Fur family K03711 - - 0.000000000000000000000000000007453 127.0
TLS3_k127_570593_7 Transglycosylase associated protein - - - 0.0000000000000000000000008925 108.0
TLS3_k127_5718299_0 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000003475 186.0
TLS3_k127_5718299_1 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.0000000000000000000000000000000000000006162 159.0
TLS3_k127_572996_0 Sulfatase K01138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 498.0
TLS3_k127_572996_1 domain, Protein - GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.0000000003566 73.0
TLS3_k127_572996_2 lipoprotein biosynthetic process K13292 - - 0.000001816 53.0
TLS3_k127_5743084_0 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 375.0
TLS3_k127_5743084_1 PFAM Nickel-dependent hydrogenase, large subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 317.0
TLS3_k127_5743084_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.00000000000000000000000000000000000004538 144.0
TLS3_k127_5771483_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0000000000000000000000000000000000000000007044 160.0
TLS3_k127_5771483_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000001703 116.0
TLS3_k127_577600_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 509.0
TLS3_k127_577600_1 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 424.0
TLS3_k127_577600_2 translation release factor activity - - - 0.0000000000000000000000000000000718 136.0
TLS3_k127_5778257_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 364.0
TLS3_k127_5778257_1 Lysin motif - - - 0.00000000000000000000000000000000000000000000000002117 198.0
TLS3_k127_5778257_2 NmrA-like family - - - 0.0000000000000000000000000106 119.0
TLS3_k127_5778257_3 - - - - 0.0000000000000000001272 94.0
TLS3_k127_5778257_4 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000003027 75.0
TLS3_k127_5778257_5 - - - - 0.00000000004319 73.0
TLS3_k127_5778257_6 PFAM ThiamineS - - - 0.00002779 55.0
TLS3_k127_5782118_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 396.0
TLS3_k127_5782118_1 PFAM Roadblock LC7 family protein K07131 - - 0.0000000000000000000000000000000000000000000133 166.0
TLS3_k127_5800967_0 Heat shock 70 kDa protein K04043 - - 1.016e-279 872.0
TLS3_k127_5800967_1 PFAM sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 438.0
TLS3_k127_5800967_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 411.0
TLS3_k127_5800967_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 329.0
TLS3_k127_5800967_4 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009455 325.0
TLS3_k127_5800967_5 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 298.0
TLS3_k127_5800967_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000001271 139.0
TLS3_k127_5800967_7 Methylates ribosomal protein L11 K02687 - - 0.000000000000000000000000000004234 124.0
TLS3_k127_582860_0 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001303 241.0
TLS3_k127_582860_1 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000001649 208.0
TLS3_k127_582860_2 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000000000000000000000000000002637 159.0
TLS3_k127_582860_3 PFAM glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000001601 119.0
TLS3_k127_5832566_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 336.0
TLS3_k127_5832566_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000002125 145.0
TLS3_k127_5832566_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000005503 130.0
TLS3_k127_5833964_0 ABC transporter, ATP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 359.0
TLS3_k127_5833964_1 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002179 247.0
TLS3_k127_5833964_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000009097 85.0
TLS3_k127_5833964_3 - - - - 0.00000000000004205 77.0
TLS3_k127_5850827_0 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 367.0
TLS3_k127_5850827_1 rRNA (adenine-N6,N6-)-dimethyltransferase activity K00561,K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182,2.1.1.184 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 306.0
TLS3_k127_5850827_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000000000000003022 217.0
TLS3_k127_5850827_3 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000004232 198.0
TLS3_k127_5850827_4 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000001415 144.0
TLS3_k127_5850827_5 PFAM Rhomboid family - - - 0.000000000000000000000000000001995 128.0
TLS3_k127_5850827_6 - - - - 0.00000000000001539 78.0
TLS3_k127_5872579_0 PFAM glycosyl transferase, family 51 - - - 5.593e-207 686.0
TLS3_k127_5872579_1 FAD dependent oxidoreductase K15736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 518.0
TLS3_k127_5872579_2 Polysaccharide biosynthesis protein K01709 - 4.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 385.0
TLS3_k127_5872579_3 regulation of translation K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.000000000004516 73.0
TLS3_k127_5872579_4 dephospho-CoA kinase activity - - - 0.000000000007987 75.0
TLS3_k127_5872579_5 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000001957 68.0
TLS3_k127_5872579_6 transferase activity, transferring glycosyl groups - - - 0.0000003463 54.0
TLS3_k127_588013_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 325.0
TLS3_k127_588013_1 COG0668 Small-conductance mechanosensitive channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002449 261.0
TLS3_k127_588013_2 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000624 250.0
TLS3_k127_588013_3 NUDIX domain - - - 0.0000000000000000000000000000000000002756 148.0
TLS3_k127_588013_4 Domain of unknown function (DU1801) - - - 0.0000000000000000000000001112 110.0
TLS3_k127_5880189_0 alanine racemase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009869 360.0
TLS3_k127_5880189_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000008448 264.0
TLS3_k127_5880189_2 Winged helix DNA-binding domain - - - 0.000000000000000000000000009561 113.0
TLS3_k127_5890302_0 COGs COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000935 386.0
TLS3_k127_5890302_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 309.0
TLS3_k127_5890302_2 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000006146 190.0
TLS3_k127_5890302_3 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000003548 114.0
TLS3_k127_5890302_4 COG1309 Transcriptional regulator - - - 0.00000000000000000004381 98.0
TLS3_k127_5890302_5 ABC-2 family transporter protein K01992 - - 0.000000000000001264 78.0
TLS3_k127_5891256_0 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 491.0
TLS3_k127_5891256_1 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 357.0
TLS3_k127_5891256_2 Exopolysaccharide synthesis, ExoD - - - 0.00000000000000000000000000000000000000000000000000000000000000231 224.0
TLS3_k127_5891256_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000002567 80.0
TLS3_k127_5930807_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 480.0
TLS3_k127_5930807_1 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 462.0
TLS3_k127_5930807_2 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000003807 184.0
TLS3_k127_5944712_0 helix_turn_helix, Lux Regulon K03556 - - 0.0 1028.0
TLS3_k127_5944712_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 398.0
TLS3_k127_5944712_10 DJ-1/PfpI family - - - 0.0000001493 54.0
TLS3_k127_5944712_2 membrane protein (DUF2306) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001063 251.0
TLS3_k127_5944712_3 Transposase K07496 - - 0.0000000000000000000000000000000000000000000000000000000001403 216.0
TLS3_k127_5944712_4 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000002662 216.0
TLS3_k127_5944712_5 - - - - 0.000000000000000000000000000000000000000000000000000003501 198.0
TLS3_k127_5944712_6 - - - - 0.00000000000000000000000000000000000000000000000000001267 203.0
TLS3_k127_5944712_7 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000003109 149.0
TLS3_k127_5944712_8 Multicopper oxidase - - - 0.000000000000000000000000001158 117.0
TLS3_k127_5944712_9 - - - - 0.000000000000000000000001654 105.0
TLS3_k127_5944937_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 9.374e-284 894.0
TLS3_k127_5944937_1 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000001115 178.0
TLS3_k127_5944937_2 Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000539 122.0
TLS3_k127_595115_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.951e-317 979.0
TLS3_k127_5951199_0 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 381.0
TLS3_k127_5951199_1 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 377.0
TLS3_k127_5951199_2 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006602 280.0
TLS3_k127_5952968_0 beta-glucosidase activity K05350,K21000 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 441.0
TLS3_k127_5952968_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000003309 248.0
TLS3_k127_5952968_2 Fe-S oxidoreductase - - - 0.000000007253 61.0
TLS3_k127_6006041_0 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 331.0
TLS3_k127_6006041_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000005025 184.0
TLS3_k127_6006041_2 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000474 151.0
TLS3_k127_6006041_3 Transcriptional regulator, LysR family K02019 - - 0.00000000000000000000003038 104.0
TLS3_k127_601518_0 PFAM peptidase U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 480.0
TLS3_k127_601518_1 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 373.0
TLS3_k127_601518_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A - - - 0.00000000000000000000000000000000000000000000000000005036 192.0
TLS3_k127_6015712_0 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000004426 177.0
TLS3_k127_6015712_1 Glycosyl transferase family 2 K07011 - - 0.00000000000000861 83.0
TLS3_k127_6015712_2 glycosyl transferase group 1 - - - 0.00000001408 66.0
TLS3_k127_6018432_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 458.0
TLS3_k127_6018432_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 424.0
TLS3_k127_6018432_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 391.0
TLS3_k127_6018432_3 ribonucleoside-diphosphate reductase activity K00525,K21636 - 1.1.98.6,1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 354.0
TLS3_k127_6018432_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000005764 197.0
TLS3_k127_6018432_5 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000001477 101.0
TLS3_k127_6018432_6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.0007475 51.0
TLS3_k127_6019277_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000006766 245.0
TLS3_k127_6019277_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000116 199.0
TLS3_k127_6021317_0 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000001094 242.0
TLS3_k127_6021317_1 COG0437 Fe-S-cluster-containing hydrogenase components 1 K00184 - - 0.00000000000000000000000000000000000000000000000000000000009942 213.0
TLS3_k127_6021317_2 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000001592 201.0
TLS3_k127_6021317_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07777 - 2.7.13.3 0.00000000000000000000000000000000000002245 149.0
TLS3_k127_6021317_4 denitrification pathway - - - 0.00000000004227 74.0
TLS3_k127_60337_0 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000007561 268.0
TLS3_k127_60337_1 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.00000000000000000000000000000000000000000000000000000000000000000000006264 252.0
TLS3_k127_60337_2 PFAM glycoside hydrolase family 39 - - - 0.0000000000000000000000000000003831 128.0
TLS3_k127_6035382_0 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 357.0
TLS3_k127_6035382_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007478 254.0
TLS3_k127_6035382_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000073 203.0
TLS3_k127_6035781_0 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 6.327e-250 792.0
TLS3_k127_6035781_1 PFAM CBS domain containing protein K04767 - - 0.0000000000000000000000000000000000182 139.0
TLS3_k127_6044021_0 PFAM Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 408.0
TLS3_k127_6044021_1 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 361.0
TLS3_k127_6044021_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 306.0
TLS3_k127_6044021_3 atpase related to the helicase subunit of the holliday junction resolvase - - - 0.00000000000000000000000000000000000000000000000000000000006532 210.0
TLS3_k127_6050209_0 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 359.0
TLS3_k127_6050209_1 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001112 259.0
TLS3_k127_6050209_2 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000000000000000000000000006745 171.0
TLS3_k127_6050209_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000005575 162.0
TLS3_k127_6050209_4 - - - - 0.0000000000000000000001159 107.0
TLS3_k127_6050209_5 Protein of unknown function (DUF1679) - - - 0.0002746 48.0
TLS3_k127_6065934_0 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 408.0
TLS3_k127_6065934_1 PFAM ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000001128 188.0
TLS3_k127_6065934_2 cell envelope-related transcriptional attenuator - - - 0.00000000000000000000000000000000000000004502 170.0
TLS3_k127_6088338_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 326.0
TLS3_k127_6088338_1 NUDIX domain - - - 0.0000007763 58.0
TLS3_k127_609322_0 AAA ATPase domain - - - 2.5e-300 962.0
TLS3_k127_609322_1 membrane K13277,K15125,K15539 - - 1.642e-245 802.0
TLS3_k127_609322_2 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000298 155.0
TLS3_k127_609322_3 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000006189 166.0
TLS3_k127_6126504_0 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 537.0
TLS3_k127_6126504_1 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 331.0
TLS3_k127_6126504_2 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000008356 145.0
TLS3_k127_6126504_3 ATPase, AAA superfamily K06921 - - 0.0000000000000000000000000001487 124.0
TLS3_k127_6138827_0 PFAM IstB domain protein ATP-binding protein K02315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 455.0
TLS3_k127_6138827_1 - - - - 0.00000000000000000000000000000000000000000000000000000000002783 212.0
TLS3_k127_6138827_2 TIGRFAM primosome, DnaD subunit - - - 0.000000000000000000000000001316 114.0
TLS3_k127_6138827_3 Peptidase_C39 like family - - - 0.0000002515 59.0
TLS3_k127_6147625_0 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 591.0
TLS3_k127_6147625_1 homoserine kinase type II (Protein kinase fold) - - - 0.00000000000000000000000000000000000000000000000001201 193.0
TLS3_k127_6147625_2 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000001872 143.0
TLS3_k127_6169277_0 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000001747 228.0
TLS3_k127_6169277_1 AAA ATPase domain - - - 0.0000000001611 74.0
TLS3_k127_6188745_0 PFAM UvrD REP helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 587.0
TLS3_k127_6188745_1 Belongs to the glycosyl hydrolase family 6 K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 480.0
TLS3_k127_6188745_2 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005412 271.0
TLS3_k127_6188745_3 AAA domain - - - 0.00000000000000000000000000000000000000000002287 165.0
TLS3_k127_6188745_4 Homeodomain-like domain - - - 0.0000000000000000005242 89.0
TLS3_k127_6188745_5 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 0.000000000000006002 81.0
TLS3_k127_6188745_6 IMG reference gene - - - 0.000000000002467 70.0
TLS3_k127_6188745_7 ATPase domain predominantly from Archaea K06921 - - 0.0002532 48.0
TLS3_k127_6189862_0 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 3.934e-214 682.0
TLS3_k127_6189862_1 WD domain, G-beta repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 563.0
TLS3_k127_6189862_2 elongation factor Tu domain 2 protein K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 336.0
TLS3_k127_6189862_3 CHAT domain - - - 0.00000000000000000000000000000000000000005791 168.0
TLS3_k127_6189862_4 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000005091 156.0
TLS3_k127_6189862_5 phosphatase K14165 - 3.1.3.16,3.1.3.48 0.00000000000000009347 87.0
TLS3_k127_6218597_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K15654 - - 3.908e-217 702.0
TLS3_k127_6243317_0 Peptidase family M20/M25/M40 K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000003964 265.0
TLS3_k127_6243317_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000002926 221.0
TLS3_k127_6243317_2 NB-ARC domain - - - 0.0000000000000000005044 102.0
TLS3_k127_6243317_3 FeoC like transcriptional regulator - - - 0.000005019 51.0
TLS3_k127_624427_0 PFAM metal-dependent phosphohydrolase, HD sub domain K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007523 456.0
TLS3_k127_624427_1 Phosphomethylpyrimidine kinase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000005377 205.0
TLS3_k127_624427_2 Flp pilus assembly protein CpaB K02279 - - 0.000000000000000000000006719 115.0
TLS3_k127_624427_3 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.00000000002763 75.0
TLS3_k127_624427_4 Glyco_18 - - - 0.00002424 55.0
TLS3_k127_6247962_0 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 611.0
TLS3_k127_6247962_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000002194 168.0
TLS3_k127_6247962_2 Transcriptional regulator K03709 - - 0.0000000000000000000000000000000000004126 149.0
TLS3_k127_6247962_3 Glyoxalase-like domain - - - 0.00000000000000000000000000000000007939 137.0
TLS3_k127_6247962_4 - - - - 0.00000000000000000000000001001 114.0
TLS3_k127_6247962_5 FeoA K04758 - - 0.00000000000000000003635 100.0
TLS3_k127_6247962_6 FeoA K04758 - - 0.0000007985 54.0
TLS3_k127_6253715_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000008909 190.0
TLS3_k127_6253715_1 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.0000133 54.0
TLS3_k127_6255310_0 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 469.0
TLS3_k127_6255310_1 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 422.0
TLS3_k127_6255310_2 SMART protein phosphatase 2C domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 439.0
TLS3_k127_6255310_3 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 323.0
TLS3_k127_6255310_4 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000531 250.0
TLS3_k127_6255310_5 PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000009257 224.0
TLS3_k127_6255310_6 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.00000000000000000000000000001624 122.0
TLS3_k127_6255310_7 STAS domain K04749 - - 0.0000000000000003647 83.0
TLS3_k127_6255310_8 STAS domain - - - 0.0000000004152 66.0
TLS3_k127_6261002_0 Protein-glutamate methylesterase K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002035 297.0
TLS3_k127_6261002_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000002562 165.0
TLS3_k127_6261002_2 response regulator K07689 - - 0.0000000000000000000000000103 114.0
TLS3_k127_6261002_3 chromosome segregation - - - 0.0000000000000004296 83.0
TLS3_k127_6266464_0 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 495.0
TLS3_k127_6266464_1 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001132 278.0
TLS3_k127_6266464_2 PFAM lipopolysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008066 284.0
TLS3_k127_6270978_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 608.0
TLS3_k127_6270978_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829,K19969,K21342 - 2.7.1.71,4.2.3.152,4.2.3.154,4.2.3.4 0.000000000000000000000000000000000000000000000001281 178.0
TLS3_k127_6270978_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000437 142.0
TLS3_k127_6271048_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 5.215e-202 638.0
TLS3_k127_6271048_1 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000002038 218.0
TLS3_k127_6271048_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000001919 142.0
TLS3_k127_6271048_3 Chitinase class I K03791 - - 0.0000000000000000000007017 111.0
TLS3_k127_6275447_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 417.0
TLS3_k127_6275447_1 CHRD domain - - - 0.000000000000000000000000000000000000000001434 161.0
TLS3_k127_6275447_2 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000001962 141.0
TLS3_k127_6275447_3 - - - - 0.000000000000000000000000008312 126.0
TLS3_k127_6275447_5 LVIVD repeat - - - 0.00000232 59.0
TLS3_k127_6280190_0 PFAM AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 485.0
TLS3_k127_6280190_1 RNA polymerase II transcriptional preinitiation complex assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000001753 249.0
TLS3_k127_6280190_2 zinc ion binding - - - 0.000000000000006076 80.0
TLS3_k127_6308585_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 8.926e-307 955.0
TLS3_k127_6308585_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 6.37e-200 629.0
TLS3_k127_6308585_2 Fructose-bisphosphate aldolase class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 512.0
TLS3_k127_6308585_3 rRNA (uridine-N3-)-methyltransferase activity K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.0000000000000000000000000000000000000000001951 166.0
TLS3_k127_6309804_0 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000003042 229.0
TLS3_k127_6309804_1 cellulose binding - - - 0.000000000000000000000000000000003271 138.0
TLS3_k127_6313402_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 3.872e-289 905.0
TLS3_k127_6313402_1 ATP-grasp domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 439.0
TLS3_k127_6313402_2 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122,K00335 - 1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 398.0
TLS3_k127_6313402_3 Formyl transferase K00604,K11175 - 2.1.2.2,2.1.2.9 0.000000000000000000000000000000000000000000000000000000000003559 220.0
TLS3_k127_6313402_4 Bacterial Fe(2+) trafficking - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887 - 0.00000000000000000000000000000000002581 137.0
TLS3_k127_6314984_0 AAA ATPase domain - - - 1.494e-239 759.0
TLS3_k127_6314984_1 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 493.0
TLS3_k127_6314984_2 Soluble NSF attachment protein, SNAP - - - 0.0000000000000000000000000001616 128.0
TLS3_k127_6314984_3 protein conserved in bacteria - - - 0.000005592 57.0
TLS3_k127_6316144_0 Belongs to the glycosyl hydrolase 32 family K03332 GO:0003674,GO:0003824,GO:0004553,GO:0004564,GO:0005975,GO:0005984,GO:0005985,GO:0005987,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016052,GO:0016787,GO:0016798,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575 3.2.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 520.0
TLS3_k127_6316144_1 COG1175 ABC-type sugar transport systems permease components K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 444.0
TLS3_k127_6316144_2 COG0395 ABC-type sugar transport system permease component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 353.0
TLS3_k127_6316144_3 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 327.0
TLS3_k127_6316144_4 Cytochrome oxidase complex assembly protein 1 - - - 0.0000191 54.0
TLS3_k127_633873_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001001 261.0
TLS3_k127_633873_2 Transposase K07496 - - 0.00000004086 57.0
TLS3_k127_6348126_0 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 612.0
TLS3_k127_6348126_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00177 - 1.2.7.1,1.2.7.3 0.0000000000000000000000000000000000000000000000000001804 190.0
TLS3_k127_6356862_0 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 349.0
TLS3_k127_6356862_1 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 287.0
TLS3_k127_6356862_2 FtsJ-like methyltransferase K06968 - 2.1.1.186 0.00000000000008934 78.0
TLS3_k127_6356862_3 MFS_1 like family - - - 0.0000000006981 71.0
TLS3_k127_636178_0 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 3.264e-211 673.0
TLS3_k127_636178_1 PAS domain containing protein - - - 0.00000000000000000000000000000001927 133.0
TLS3_k127_636178_2 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.000000000000000000000000000004687 126.0
TLS3_k127_6362312_0 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 506.0
TLS3_k127_6362312_1 Belongs to the peptidase S51 family K05995 - 3.4.13.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 407.0
TLS3_k127_6362312_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 361.0
TLS3_k127_6362312_3 Serine hydrolase K07002 - - 0.00000000000000000000000000000000000000000000000000000000000000001883 228.0
TLS3_k127_6362312_4 PFAM bifunctional deaminase-reductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000917 212.0
TLS3_k127_6362312_5 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000006304 179.0
TLS3_k127_6362312_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07032 - - 0.00000000000000000000000007913 113.0
TLS3_k127_6362312_7 - - - - 0.000000000000000004391 90.0
TLS3_k127_6362312_8 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000002548 73.0
TLS3_k127_6369556_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 391.0
TLS3_k127_6369556_1 Protease prsW family - - - 0.0000000000000000000000000000000000000000000000000000003151 205.0
TLS3_k127_6369556_2 Subtilase family K14645 - - 0.00000000000000000000000000000000004459 143.0
TLS3_k127_6369556_3 - - - - 0.00000000000000000000006801 105.0
TLS3_k127_6369556_4 Domain of unknown function (DUF4342) - - - 0.0000000000359 68.0
TLS3_k127_6371683_0 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 291.0
TLS3_k127_6371683_1 Protein of unknown function DUF89 - - - 0.0000000000000000000000000000000000000000000000000000000000000003247 234.0
TLS3_k127_6371683_2 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000000000000006256 185.0
TLS3_k127_6371683_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000008758 151.0
TLS3_k127_639495_0 TIGRFAM phenylacetate-CoA oxygenase, PaaJ subunit K02612 - - 0.000000000000000000000000000000000000000000000000000001961 195.0
TLS3_k127_639495_1 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000004836 197.0
TLS3_k127_639495_2 NUDIX domain - - - 0.000000000003281 79.0
TLS3_k127_639495_3 Beta-lactamase enzyme family - - - 0.00000000007359 72.0
TLS3_k127_643130_0 TIGRFAM magnesium chelatase, H subunit K03403 - 6.6.1.1 0.0 1227.0
TLS3_k127_643130_1 cell redox homeostasis K02199 - - 0.0000512 54.0
TLS3_k127_6432492_0 ATP hydrolysis coupled proton transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 314.0
TLS3_k127_6432492_1 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000005567 140.0
TLS3_k127_6432492_2 IMG reference gene - - - 0.000000000000000000000004043 109.0
TLS3_k127_6432492_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000001564 64.0
TLS3_k127_6441970_0 Glycosyltransferase Family 4 - - - 0.0 1240.0
TLS3_k127_6441970_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.998e-232 730.0
TLS3_k127_6441970_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000001689 85.0
TLS3_k127_6441970_11 helix_turn_helix, Lux Regulon - - - 0.000000000006155 70.0
TLS3_k127_6441970_12 Belongs to the UPF0225 family K09858 - - 0.00001608 50.0
TLS3_k127_6441970_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.065e-194 625.0
TLS3_k127_6441970_3 beta-1,4-mannooligosaccharide phosphorylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 562.0
TLS3_k127_6441970_4 oxidoreductase activity, acting on diphenols and related substances as donors K09471 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 452.0
TLS3_k127_6441970_5 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001857 285.0
TLS3_k127_6441970_6 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001421 270.0
TLS3_k127_6441970_7 permease - - - 0.00000000000000000000000000000000000000000000000000001523 204.0
TLS3_k127_6441970_8 - - - - 0.0000000000000000000000000000000000001872 143.0
TLS3_k127_6441970_9 - - - - 0.0000000000000000000000000000001221 129.0
TLS3_k127_6447434_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.045e-215 677.0
TLS3_k127_6447434_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.874e-209 663.0
TLS3_k127_6447434_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000003557 242.0
TLS3_k127_6447434_3 rod shape-determining protein mreB K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000004522 225.0
TLS3_k127_6447434_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000003884 139.0
TLS3_k127_6447434_5 Psort location CytoplasmicMembrane, score - - - 0.000000000000000002051 92.0
TLS3_k127_6449011_0 - - - - 0.000000000000000000000000000000000000001556 154.0
TLS3_k127_6449011_1 Uncharacterised nucleotidyltransferase - - - 0.0000000000001538 82.0
TLS3_k127_6449011_2 HPr kinase - - - 0.00000131 59.0
TLS3_k127_6449011_3 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000001772 61.0
TLS3_k127_6452441_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 547.0
TLS3_k127_6452441_1 PFAM type II secretion system protein E K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 512.0
TLS3_k127_6452441_2 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 411.0
TLS3_k127_6452441_3 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002633 271.0
TLS3_k127_6452441_4 FeoA K03709 - - 0.0000000000000000000000000000000000000000000000000004306 191.0
TLS3_k127_6452441_5 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.00000000000000000000000000002696 120.0
TLS3_k127_6452441_6 - - - - 0.00000001106 59.0
TLS3_k127_6452441_7 - - - - 0.0001259 48.0
TLS3_k127_6461185_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1386.0
TLS3_k127_6461185_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 318.0
TLS3_k127_6461185_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000008352 145.0
TLS3_k127_6462012_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002843 274.0
TLS3_k127_6462012_1 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001249 262.0
TLS3_k127_6462012_2 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000006018 258.0
TLS3_k127_6462012_3 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.0000000000000000000000000000000000000001153 163.0
TLS3_k127_6462012_4 PFAM Rhodanese domain protein - - - 0.0000000000000000000000000000000000000009908 152.0
TLS3_k127_6462012_5 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.00000000000000000003913 91.0
TLS3_k127_6462012_7 histidine kinase HAMP region domain protein - - - 0.0000001128 61.0
TLS3_k127_6467619_0 bacterial-type flagellum-dependent cell motility K15923 - 3.2.1.51 1.517e-244 762.0
TLS3_k127_6467619_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000002633 106.0
TLS3_k127_6472060_0 IMP cyclohydrolase activity. It is involved in the biological process described with purine nucleotide biosynthetic process K00602 GO:0003360,GO:0003674,GO:0003824,GO:0003937,GO:0004643,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006760,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009235,GO:0009259,GO:0009260,GO:0009396,GO:0009611,GO:0009987,GO:0010035,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019238,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0021537,GO:0021543,GO:0021549,GO:0021987,GO:0022037,GO:0030900,GO:0030902,GO:0031099,GO:0031100,GO:0032501,GO:0032502,GO:0033013,GO:0034641,GO:0034654,GO:0042060,GO:0042221,GO:0042398,GO:0042558,GO:0042559,GO:0042802,GO:0042803,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046394,GO:0046452,GO:0046483,GO:0046653,GO:0046654,GO:0046983,GO:0048513,GO:0048731,GO:0048856,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0060322,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.1.2.3,3.5.4.10 2.916e-234 736.0
TLS3_k127_6472060_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 531.0
TLS3_k127_6472060_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002251 274.0
TLS3_k127_6472060_3 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000009295 223.0
TLS3_k127_6472060_4 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000001618 169.0
TLS3_k127_6472060_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000001998 108.0
TLS3_k127_6472850_0 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 302.0
TLS3_k127_6472850_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000003812 222.0
TLS3_k127_6472850_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000008306 223.0
TLS3_k127_650417_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 3.081e-276 870.0
TLS3_k127_650417_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 314.0
TLS3_k127_650417_2 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 308.0
TLS3_k127_650417_3 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000007318 185.0
TLS3_k127_650417_4 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000001476 200.0
TLS3_k127_650417_5 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000002845 174.0
TLS3_k127_6505351_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 423.0
TLS3_k127_6505351_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000001582 233.0
TLS3_k127_6505351_2 PFAM PDZ DHR GLGF domain protein K03797 - 3.4.21.102 0.00000000000000000000000000000002301 137.0
TLS3_k127_6505808_0 fatty acid desaturase K03921 - 1.14.19.11,1.14.19.2,1.14.19.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 293.0
TLS3_k127_6505808_1 cell envelope-related transcriptional attenuator - - - 0.00000000000000000000000000000000000000005436 169.0
TLS3_k127_6505808_2 Protein of unknown function DUF58 - - - 0.00000000000001013 79.0
TLS3_k127_6505808_3 Belongs to the peptidase S16 family K07177 - - 0.00001046 56.0
TLS3_k127_651991_0 Glycosyl hydrolase family 1 K00067 - 1.1.1.133 4.348e-270 846.0
TLS3_k127_651991_1 PFAM UDP-galactopyranose mutase, C-terminal K01854 - 5.4.99.9 3.41e-198 626.0
TLS3_k127_651991_10 response to heat K03668,K09914 - - 0.000000000006926 68.0
TLS3_k127_651991_2 helix_turn_helix, Lux Regulon K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 489.0
TLS3_k127_651991_3 Coenzyme F390 synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 421.0
TLS3_k127_651991_4 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008571 413.0
TLS3_k127_651991_5 cellulase activity K01183 - 3.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000002063 259.0
TLS3_k127_651991_6 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000002074 207.0
TLS3_k127_651991_7 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000006359 174.0
TLS3_k127_651991_8 - - - - 0.00000000000000000000002426 111.0
TLS3_k127_651991_9 Cell Wall K01448 - 3.5.1.28 0.0000000000006475 81.0
TLS3_k127_6521705_0 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 360.0
TLS3_k127_6521705_1 PFAM Ribonuclease BN-like family K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 360.0
TLS3_k127_6521705_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002772 262.0
TLS3_k127_6521705_3 Alkaline and neutral invertase - - - 0.000000000000000000000009245 115.0
TLS3_k127_6521705_4 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 0.0000000000000006862 79.0
TLS3_k127_6526142_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 3.24e-299 924.0
TLS3_k127_6526142_1 PFAM amidohydrolase K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 490.0
TLS3_k127_6526142_2 PFAM phenylalanine histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 451.0
TLS3_k127_6526142_3 - - - - 0.0000000000000001772 84.0
TLS3_k127_653336_0 Belongs to the glycosyl hydrolase 31 family - - - 3.829e-279 881.0
TLS3_k127_653336_1 Rare lipoprotein A K20628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 289.0
TLS3_k127_653336_2 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000003946 170.0
TLS3_k127_653336_3 Membrane proteins related to metalloendopeptidases - - - 0.000004918 58.0
TLS3_k127_6542569_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 8.029e-274 865.0
TLS3_k127_6542569_1 DNA recombination-mediator protein A K03168,K04096 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 390.0
TLS3_k127_6542569_2 Mannose-6-phosphate isomerase K00971,K01840,K16011 - 2.7.7.13,5.3.1.8,5.4.2.8 0.000000000000000000000000000000000000000000000000000001371 206.0
TLS3_k127_6542569_3 ribosome binding K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000008676 146.0
TLS3_k127_6542569_4 Belongs to the UPF0109 family K06960 - - 0.000000000000000000002526 96.0
TLS3_k127_655140_0 trisaccharide binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 599.0
TLS3_k127_655140_1 WD-40 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 314.0
TLS3_k127_6558220_0 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 443.0
TLS3_k127_6558220_1 Protein of unknown function DUF126 K09128 - - 0.000000000000000000000000000001019 126.0
TLS3_k127_6558220_2 Acetyltransferase (GNAT) domain - - - 0.000000000008742 67.0
TLS3_k127_6558220_3 - - - - 0.00002215 55.0
TLS3_k127_656300_0 PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein K00341 - 1.6.5.3 5.8e-206 666.0
TLS3_k127_656300_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 555.0
TLS3_k127_656300_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.000000000000000000000000000009136 121.0
TLS3_k127_656300_3 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000001412 104.0
TLS3_k127_656300_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000005411 63.0
TLS3_k127_6564079_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000005748 138.0
TLS3_k127_6564079_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000001921 127.0
TLS3_k127_6564079_2 proteolysis K21140 - 3.13.1.6 0.0000000000000000000000001057 111.0
TLS3_k127_657793_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009445 310.0
TLS3_k127_657793_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000009081 203.0
TLS3_k127_657793_2 DNA-binding transcription factor activity K03892 - - 0.000000000000001586 79.0
TLS3_k127_6579990_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 3.862e-234 739.0
TLS3_k127_6579990_1 CO dehydrogenase flavoprotein C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000001686 212.0
TLS3_k127_6587685_0 Amino acid adenylation domain - - - 3.509e-204 658.0
TLS3_k127_6588704_0 PFAM RNA binding S1 domain protein K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 326.0
TLS3_k127_6588704_1 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000537 274.0
TLS3_k127_6588704_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000001102 221.0
TLS3_k127_6603587_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 1.214e-241 765.0
TLS3_k127_6603587_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000005273 71.0
TLS3_k127_661600_0 Phage shock protein A K03969 - - 0.000000000000000000000000000000000000000000000000000000000005205 215.0
TLS3_k127_661600_1 Two component regulator propeller - - - 0.000000000000000000000000000000000000000005857 177.0
TLS3_k127_661600_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000004521 100.0
TLS3_k127_661600_3 cheY-homologous receiver domain - - - 0.0000000000000001901 94.0
TLS3_k127_6619189_0 PFAM Diacylglycerol kinase, catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000001579 244.0
TLS3_k127_6619189_1 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000003061 234.0
TLS3_k127_6619189_3 PHP-associated - - - 0.00000000000000001632 83.0
TLS3_k127_6620875_0 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 529.0
TLS3_k127_6620875_1 ABC transporter K17215 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 488.0
TLS3_k127_6620875_2 Periplasmic binding proteins and sugar binding domain of LacI family K17202 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 354.0
TLS3_k127_6620875_3 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004087 249.0
TLS3_k127_6620875_4 purine nucleotide biosynthetic process K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000004831 231.0
TLS3_k127_6620875_5 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000000000007987 175.0
TLS3_k127_6620875_6 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.000000000000000000000001326 106.0
TLS3_k127_6626167_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K15408 - 1.9.3.1 2.57e-291 918.0
TLS3_k127_6626167_1 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 290.0
TLS3_k127_6626167_2 MgtC family K07507 - - 0.000000000000000000000000000000000000000005583 158.0
TLS3_k127_6632497_0 Glycosyl hydrolases family 2 K01192 - 3.2.1.25 7.454e-298 935.0
TLS3_k127_6632497_1 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000008356 168.0
TLS3_k127_6632497_2 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000001075 123.0
TLS3_k127_6635018_0 TIGRFAM molybdenum cofactor synthesis domain K03750,K07219 - 2.10.1.1 1.504e-242 767.0
TLS3_k127_6635018_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 333.0
TLS3_k127_6635018_2 PFAM BMC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 318.0
TLS3_k127_6635018_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001878 272.0
TLS3_k127_6635018_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000123 181.0
TLS3_k127_6635018_5 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.0000000000000000000000000000000000000000000003108 176.0
TLS3_k127_6635018_6 COGs COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein K04027 - - 0.000000000000000000000000000000000000001558 149.0
TLS3_k127_6635018_8 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000000000008394 104.0
TLS3_k127_6644140_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009024 383.0
TLS3_k127_6644140_1 - - - - 0.0000000000000000000000000002494 134.0
TLS3_k127_6644140_2 - - - - 0.00000000000000000000000002484 114.0
TLS3_k127_6644140_3 - - - - 0.00001178 57.0
TLS3_k127_6644140_4 diguanylate cyclase K19168 - - 0.00004754 45.0
TLS3_k127_6647750_0 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002368 267.0
TLS3_k127_6647750_1 PFAM Stage V sporulation protein S K06416 - - 0.000000000000000000000000000131 117.0
TLS3_k127_6647750_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000408 113.0
TLS3_k127_664796_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 465.0
TLS3_k127_664796_1 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 317.0
TLS3_k127_666397_0 Sodium:sulfate symporter transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 554.0
TLS3_k127_666397_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 359.0
TLS3_k127_666397_2 acetyltransferase - - - 0.000000000000000000000000000000000000000000003937 166.0
TLS3_k127_666397_3 hyperosmotic response - - - 0.0000001248 61.0
TLS3_k127_6696878_0 Protein of unknown function (DUF1706) - - - 0.0000000000000000000000000008753 119.0
TLS3_k127_6696878_1 Protein of unknown function (DUF1706) - - - 0.0000000000000000000838 96.0
TLS3_k127_6696878_2 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit - - - 0.00001318 55.0
TLS3_k127_670257_0 peptidase S9 prolyl oligopeptidase active site K01303 - 3.4.19.1 1.131e-243 770.0
TLS3_k127_670257_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 407.0
TLS3_k127_670257_2 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 329.0
TLS3_k127_670257_3 Anaphase-promoting complex subunit 4 WD40 domain - - - 0.0000000000000000000000000000000000000000000000001055 185.0
TLS3_k127_6710603_0 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 310.0
TLS3_k127_6710603_1 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000007331 220.0
TLS3_k127_6710603_2 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000000000000001103 201.0
TLS3_k127_671305_0 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 424.0
TLS3_k127_671305_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 365.0
TLS3_k127_671305_2 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 345.0
TLS3_k127_671305_3 metallopeptidase activity K16922 - - 0.000000005181 64.0
TLS3_k127_6724502_0 Protein of unknown function DUF89 - - - 0.00000000000000000000000000000000000000000000000000611 186.0
TLS3_k127_6724502_1 Protein of unknown function (DUF3253) - - - 0.0000000000003333 74.0
TLS3_k127_6724502_2 Tetratricopeptide repeat - - - 0.00006328 55.0
TLS3_k127_6729032_0 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 1.613e-209 665.0
TLS3_k127_6730223_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 346.0
TLS3_k127_6730223_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 347.0
TLS3_k127_6730223_2 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000001936 132.0
TLS3_k127_6746716_0 DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 474.0
TLS3_k127_6746716_1 DNA binding - - - 0.00000000000000000000000000000000000000001844 160.0
TLS3_k127_6746716_2 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00038 51.0
TLS3_k127_6747235_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 526.0
TLS3_k127_6747235_1 Domain of unknown function (DUF4397) - - - 0.0000000000000000000000000000000000000000000000001568 193.0
TLS3_k127_6747235_2 Domain of unknown function (DUF4397) - - - 0.00000000000000002367 95.0
TLS3_k127_6747235_3 Anti-sigma-K factor rskA - - - 0.000000000008341 68.0
TLS3_k127_6749842_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 464.0
TLS3_k127_6749842_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000005467 264.0
TLS3_k127_6749842_2 Peptidase M10A and M12B matrixin and adamalysin - - - 0.00000000000006993 79.0
TLS3_k127_6749842_3 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000004605 59.0
TLS3_k127_6750835_0 Pyridoxal-phosphate dependent enzyme - - - 7.671e-244 760.0
TLS3_k127_6750835_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 351.0
TLS3_k127_6750835_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 340.0
TLS3_k127_6750835_3 ABC transporter substrate-binding protein PnrA-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 313.0
TLS3_k127_6750835_4 cytosine deaminase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002262 247.0
TLS3_k127_6750835_5 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000002461 252.0
TLS3_k127_6757320_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.96e-263 824.0
TLS3_k127_6757320_1 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000001502 134.0
TLS3_k127_6757320_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000003498 79.0
TLS3_k127_6758259_0 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K12528 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 487.0
TLS3_k127_6758259_1 Protein of unknown function (DUF2283) - - - 0.0000000000000000002417 89.0
TLS3_k127_6758259_2 - - - - 0.0000000000000001336 79.0
TLS3_k127_6758259_3 Winged helix-turn helix - - - 0.000000000006545 70.0
TLS3_k127_6758259_4 - - - - 0.000000003417 59.0
TLS3_k127_6759432_0 Histidine kinase-like ATPases K01768,K02488,K17763 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 497.0
TLS3_k127_6759432_1 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 374.0
TLS3_k127_6759432_2 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002018 284.0
TLS3_k127_6777010_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 436.0
TLS3_k127_6777010_1 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000488 106.0
TLS3_k127_6777010_2 mercury ion transmembrane transporter activity K07213 - - 0.000000000000003135 78.0
TLS3_k127_6777010_3 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000004045 55.0
TLS3_k127_6780041_0 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000001254 230.0
TLS3_k127_6780041_1 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000009078 107.0
TLS3_k127_6780041_2 Bacterial transcriptional activator domain - - - 0.000000002906 61.0
TLS3_k127_6780712_0 AAA domain - - - 6.618e-236 747.0
TLS3_k127_6784014_0 TIGRFAM isochorismate synthase K02361,K02552 - 5.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 487.0
TLS3_k127_6784014_1 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004762 245.0
TLS3_k127_6784014_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000007419 161.0
TLS3_k127_6784014_3 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.0000000000000000000000000000000000000002157 153.0
TLS3_k127_6784188_0 Amino acid permease - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 507.0
TLS3_k127_6784188_1 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000005144 220.0
TLS3_k127_6784188_2 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.000000000000000000000000000005988 125.0
TLS3_k127_6801251_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 304.0
TLS3_k127_6801251_1 Histidine kinase K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000004874 256.0
TLS3_k127_6801251_2 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000002411 214.0
TLS3_k127_6801251_3 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000002582 147.0
TLS3_k127_6801251_4 a CheY-like receiver domain and - - - 0.000000000000003525 77.0
TLS3_k127_6816254_0 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 546.0
TLS3_k127_6816254_1 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000001806 122.0
TLS3_k127_6816254_2 SnoaL-like domain K06893 - - 0.0000000000000000000000000001054 121.0
TLS3_k127_6816254_3 - - - - 0.0000000000000000003967 91.0
TLS3_k127_6823053_0 alginic acid biosynthetic process - - - 5.263e-278 872.0
TLS3_k127_6823053_1 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000002444 151.0
TLS3_k127_6823053_2 amine dehydrogenase activity - - - 0.0000000000000000000000006275 104.0
TLS3_k127_6829856_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 341.0
TLS3_k127_6829856_1 ATP synthesis coupled electron transport K00336 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 347.0
TLS3_k127_6829856_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000001305 248.0
TLS3_k127_6829856_3 Belongs to the complex I subunit 6 family K00339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000001808 139.0
TLS3_k127_6829856_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000003981 130.0
TLS3_k127_6829856_5 NADH ubiquinone oxidoreductase subunit 5 (Chain L) multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000001418 125.0
TLS3_k127_6842135_0 - - - - 0.000000000001609 71.0
TLS3_k127_6843864_0 PFAM SMC domain protein K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003679 293.0
TLS3_k127_6843864_1 PFAM sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006563 254.0
TLS3_k127_6843864_2 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000107 254.0
TLS3_k127_6843864_3 cheY-homologous receiver domain - - - 0.0000000000000000000000001401 111.0
TLS3_k127_6843864_4 Ribosomal protein S21 K02970 - - 0.00000000000003877 74.0
TLS3_k127_6843864_5 UbiA prenyltransferase family K04040 - 2.5.1.133,2.5.1.62 0.000003473 58.0
TLS3_k127_684660_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 423.0
TLS3_k127_684660_1 FCD domain - - - 0.000000000000000000000000000000000000000000000000000002022 199.0
TLS3_k127_684660_2 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.0000000000000000000000000000000001514 142.0
TLS3_k127_684660_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000001769 74.0
TLS3_k127_684660_4 photosynthesis - - - 0.00000000007469 64.0
TLS3_k127_6853317_0 PFAM ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 521.0
TLS3_k127_6853317_1 basic membrane K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 376.0
TLS3_k127_6853317_2 transport system permease K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 333.0
TLS3_k127_6853317_3 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 333.0
TLS3_k127_6853317_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 298.0
TLS3_k127_6853317_5 transport system permease K02057 - - 0.00000000000000000000000000000000000000000000000000001584 201.0
TLS3_k127_6860208_0 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 352.0
TLS3_k127_6860208_1 Fumarase C-terminus K01676,K01678 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000003346 248.0
TLS3_k127_6860208_2 Helix-turn-helix K21498 - - 0.000000000000000000000000000000000000000003532 157.0
TLS3_k127_6860208_3 Plasmid maintenance system killer K07334 - - 0.00000000000000000000000000000000000000015 151.0
TLS3_k127_6860208_4 - - - - 0.0000000000000000000000000000000001548 139.0
TLS3_k127_6860208_5 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.000000000000003157 80.0
TLS3_k127_6860208_6 Succinate dehydrogenase hydrophobic membrane anchor K00242 - - 0.000002458 54.0
TLS3_k127_6863748_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 5.298e-249 783.0
TLS3_k127_6863748_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 611.0
TLS3_k127_6863748_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000004847 174.0
TLS3_k127_6863748_3 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000008853 96.0
TLS3_k127_6863748_4 MarR family - - - 0.00000006879 60.0
TLS3_k127_6863748_5 PRC-barrel domain - - - 0.000001051 60.0
TLS3_k127_6872948_0 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000006312 174.0
TLS3_k127_6872948_1 PFAM phosphatidate cytidylyltransferase - - - 0.00000000000000000000000000000000001193 144.0
TLS3_k127_6872948_2 membrane K07148 - - 0.0000000000000000000002286 98.0
TLS3_k127_6872948_3 PFAM PfkB domain protein - - - 0.00000000001027 66.0
TLS3_k127_6874401_0 PFAM malic K00027,K00029 - 1.1.1.38,1.1.1.40 1.791e-227 716.0
TLS3_k127_6874401_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 317.0
TLS3_k127_6874401_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000002693 150.0
TLS3_k127_687808_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 497.0
TLS3_k127_687808_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001492 295.0
TLS3_k127_687808_2 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000114 256.0
TLS3_k127_687808_3 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000003561 149.0
TLS3_k127_687808_4 signal peptide processing K03100 - 3.4.21.89 0.0002525 54.0
TLS3_k127_6882024_0 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 571.0
TLS3_k127_6882024_1 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 364.0
TLS3_k127_6882024_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003278 282.0
TLS3_k127_6882024_3 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000000000000000000000003267 157.0
TLS3_k127_6882024_4 - - - - 0.0000000000000000000000000005717 119.0
TLS3_k127_6897928_0 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000005659 253.0
TLS3_k127_6897928_1 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000192 165.0
TLS3_k127_6897928_2 transferase activity, transferring glycosyl groups K12994 - 2.4.1.349 0.00000000000000000000002689 103.0
TLS3_k127_6903950_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 2.192e-229 726.0
TLS3_k127_6903950_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 301.0
TLS3_k127_6903950_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001951 268.0
TLS3_k127_6903950_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00338,K03615 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000002682 239.0
TLS3_k127_6903950_4 Domain of unknown function (DUF3524) - - - 0.000000000000000000000000000000000000000000000000000001131 198.0
TLS3_k127_6903950_5 FeS assembly protein IscX - - - 0.00000436 52.0
TLS3_k127_6913098_0 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000000000000004981 130.0
TLS3_k127_6913098_1 response to heat K03668,K09914 - - 0.00000000000000005167 94.0
TLS3_k127_6913128_0 serine-type endopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002224 289.0
TLS3_k127_6913128_1 serine-type endopeptidase activity - - - 0.000000000007635 68.0
TLS3_k127_6917377_0 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001988 267.0
TLS3_k127_6917377_1 PFAM RDD domain containing protein - - - 0.00000000000000000000000000000000000000000005915 170.0
TLS3_k127_6917377_2 Transcriptional modulator of MazE toxin, MazF K07171,K18841 GO:0001558,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0022607,GO:0030308,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0042802,GO:0042803,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044877,GO:0045926,GO:0046483,GO:0046700,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051259,GO:0051291,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000753 158.0
TLS3_k127_6917377_3 Transcriptional regulator antitoxin, MazE K07172 - - 0.0003912 43.0
TLS3_k127_6924294_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 420.0
TLS3_k127_6924294_1 pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000007827 264.0
TLS3_k127_6924294_2 InterPro IPR014922 - - - 0.00000000000000000000000000000000000000000000000000000001731 201.0
TLS3_k127_6924294_3 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000622 186.0
TLS3_k127_6924294_4 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000000000000000000000000000001453 190.0
TLS3_k127_6924294_5 pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000004863 155.0
TLS3_k127_6924294_6 YCII-related domain - - - 0.00000000000000000000000003885 112.0
TLS3_k127_6926691_0 Dehydrogenase E1 component K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 353.0
TLS3_k127_6926691_1 PFAM oxidoreductase, molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 300.0
TLS3_k127_6926691_2 PFAM major facilitator superfamily MFS_1 K08223 - - 0.0000000000000000000000000000000000000000000000000000000000005939 225.0
TLS3_k127_6927167_0 Domain of unknown function (DUF4129) - - - 0.000000000000000000000000000000000003985 151.0
TLS3_k127_6927167_1 pathogenesis K02417,K02519 - - 0.0000000000000004044 90.0
TLS3_k127_6927167_2 pathogenesis K02417,K02519 - - 0.00000000006631 72.0
TLS3_k127_6928902_0 Peptidase S9, prolyl oligopeptidase active site domain protein K01322 - 3.4.21.26 5.455e-248 783.0
TLS3_k127_6928902_1 PFAM Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 392.0
TLS3_k127_6928902_2 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 292.0
TLS3_k127_6928902_3 Putative inner membrane exporter, YdcZ K09936 - - 0.00000000000000000000000000000000000000000003231 165.0
TLS3_k127_6928902_4 transcriptional activator domain - - - 0.0000003328 58.0
TLS3_k127_6931684_0 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 600.0
TLS3_k127_6931684_1 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 301.0
TLS3_k127_6931684_2 ECF sigma factor K03088 - - 0.00000000000000000004483 98.0
TLS3_k127_6933356_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005985 295.0
TLS3_k127_6933356_1 enzyme binding K00567,K07443 - 2.1.1.63 0.0000000000000000000005272 102.0
TLS3_k127_6938733_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 399.0
TLS3_k127_6938733_1 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K03478 - 3.5.1.105 0.0000000000000000000000000000000000000003558 161.0
TLS3_k127_6951290_0 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 606.0
TLS3_k127_6951290_1 ABC transporter transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 552.0
TLS3_k127_6951290_2 COGs COG1132 ABC-type multidrug transport system ATPase and permease components K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 496.0
TLS3_k127_6951290_3 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006765 282.0
TLS3_k127_6958001_0 PFAM ribonucleotide reductase K00526 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 387.0
TLS3_k127_6958001_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000001115 170.0
TLS3_k127_6958001_2 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000004925 135.0
TLS3_k127_6964822_0 alpha-ribazole phosphatase activity K02226,K15634,K22305 - 3.1.3.3,3.1.3.73,5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000003162 225.0
TLS3_k127_6964822_1 Protein of unknown function (DUF3090) - - - 0.00000000000000000000000000000000000000000008425 165.0
TLS3_k127_6964822_2 phosphatidylinositol kinase activity - - - 0.000000000000000000000000000000005817 131.0
TLS3_k127_6964822_3 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.000000000000000000001884 98.0
TLS3_k127_6977360_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 609.0
TLS3_k127_6977360_1 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 488.0
TLS3_k127_6979620_0 carboxylic acid catabolic process K18334 - 4.2.1.68 1.268e-215 675.0
TLS3_k127_6979620_1 glycerophosphodiester transmembrane transport K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 419.0
TLS3_k127_6979620_2 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 391.0
TLS3_k127_6979620_3 transmembrane transport K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17242,K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008682 332.0
TLS3_k127_6979620_4 Aldo Keto reductase K17744 - 1.1.1.316 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 299.0
TLS3_k127_6979620_5 Fumarylacetoacetate (FAA) hydrolase family K01826 - 5.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 293.0
TLS3_k127_6979620_6 Amidohydrolase K07046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 291.0
TLS3_k127_6979620_7 Belongs to the RbsD FucU family K02431 GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0005996,GO:0006004,GO:0008150,GO:0008152,GO:0016853,GO:0016854,GO:0016857,GO:0019318,GO:0030246,GO:0036094,GO:0042806,GO:0044238,GO:0044281,GO:0048029,GO:0071704 5.1.3.29 0.0000000000000000000000000000000000000000000000000000002266 197.0
TLS3_k127_6990273_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000009489 205.0
TLS3_k127_6990273_1 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain K21023 - 2.7.7.65 0.00000000000000000000000000000000000003651 153.0
TLS3_k127_6990273_2 histidine kinase A domain protein - - - 0.000000000000000000000000000001001 143.0
TLS3_k127_6990273_3 diguanylate cyclase - - - 0.00000006505 67.0
TLS3_k127_6996680_0 Transposase, IS605 OrfB family K07496 - - 0.00000000000000000000001325 103.0
TLS3_k127_6996680_1 response regulator K07689 - - 0.0000000008085 64.0
TLS3_k127_6996680_2 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000002443 63.0
TLS3_k127_6996680_3 PFAM Abortive infection protein K07052 - - 0.00000001756 66.0
TLS3_k127_6996680_4 Putative transposase DNA-binding domain K07496 - - 0.0000004084 53.0
TLS3_k127_6996680_5 Phage plasmid primase P4 family - - - 0.0000005104 60.0
TLS3_k127_6997476_0 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 342.0
TLS3_k127_6997476_1 Binding-protein-dependent transport system inner membrane component K01284,K02029 - 3.4.15.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 302.0
TLS3_k127_6997476_2 PFAM ABC transporter related K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000004164 214.0
TLS3_k127_6997476_3 transmembrane transporter activity - - - 0.0000718 50.0
TLS3_k127_7000748_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.00000000000000000000000000000001573 129.0
TLS3_k127_7000748_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000000002157 104.0
TLS3_k127_7000748_2 PFAM short-chain dehydrogenase reductase SDR - - - 0.000000000000000000476 93.0
TLS3_k127_7001717_0 transmembrane transport K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17242,K17316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 352.0
TLS3_k127_7001717_1 Trypsin K04771 GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 0.000000001215 70.0
TLS3_k127_7001717_2 It is involved in the biological process described with response to stress - GO:0001671,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0008047,GO:0008150,GO:0009987,GO:0030234,GO:0031072,GO:0032781,GO:0043085,GO:0043462,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051087,GO:0051336,GO:0051345,GO:0051879,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0098772 - 0.00009572 54.0
TLS3_k127_7001878_0 Alpha amylase, catalytic domain K01187,K01208,K21575 - 3.2.1.133,3.2.1.135,3.2.1.20,3.2.1.54 3.457e-221 701.0
TLS3_k127_7001878_1 luxR family - - - 0.00000000000000000000000000000000000000000000001284 174.0
TLS3_k127_7001878_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000009704 168.0
TLS3_k127_7001878_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000009228 114.0
TLS3_k127_700964_0 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005712 276.0
TLS3_k127_700964_1 - - - - 0.000000000000003241 88.0
TLS3_k127_700964_2 PFAM ABC-2 type transporter K01992 - - 0.00000007632 63.0
TLS3_k127_7011595_0 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 530.0
TLS3_k127_7011595_1 PFAM glycosyl transferase group 1 - - - 0.0000000000000001237 85.0
TLS3_k127_7016350_0 endonuclease exonuclease phosphatase K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 485.0
TLS3_k127_7016350_1 Evidence 5 No homology to any previously reported sequences K07004 - - 0.0000000000000000000000000000000000000000000001309 192.0
TLS3_k127_7016350_2 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.000000000000000000000001083 105.0
TLS3_k127_7017992_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 455.0
TLS3_k127_7017992_1 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 301.0
TLS3_k127_7017992_2 Short-chain Dehydrogenase reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 286.0
TLS3_k127_7017992_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001414 254.0
TLS3_k127_7017992_4 protein conserved in bacteria (DUF2087) - - - 0.0000000000000000000000000000000000000000000000000000000000003044 218.0
TLS3_k127_7017992_5 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.0000000000000000000002922 103.0
TLS3_k127_7017992_6 Pfam:UPF0118 - - - 0.0000000000000001658 92.0
TLS3_k127_7017992_7 - - - - 0.00000003872 62.0
TLS3_k127_7028596_0 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 308.0
TLS3_k127_7028596_1 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000000000000000001425 227.0
TLS3_k127_7028596_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000001256 169.0
TLS3_k127_7028596_3 Domain of unknown function (DUF4260) - - - 0.0000000000000000000000000000000001501 136.0
TLS3_k127_7028596_4 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000002038 149.0
TLS3_k127_7028596_5 - - - - 0.000000000000008867 78.0
TLS3_k127_7028596_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000002932 74.0
TLS3_k127_7040747_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000007797 216.0
TLS3_k127_7040747_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000002211 196.0
TLS3_k127_7040747_2 Protein of unknown function DUF86 - - - 0.00000000000000000000000000000000000000008557 157.0
TLS3_k127_7040747_3 PFAM DSBA oxidoreductase - - - 0.00000000000000007723 85.0
TLS3_k127_7040747_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000002022 72.0
TLS3_k127_7040747_5 nucleotidyltransferase activity - - - 0.00002835 52.0
TLS3_k127_7041672_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000007846 173.0
TLS3_k127_7041672_1 Histidine kinase - - - 0.0000000000000000000000000000000698 127.0
TLS3_k127_7041672_2 Histidine kinase K03320 - - 0.00000000001775 69.0
TLS3_k127_7047666_0 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 418.0
TLS3_k127_7047666_1 Methyltransferase domain K06219 - - 0.000000000000000000000000000000000000000000000000000000003096 209.0
TLS3_k127_7047666_2 Protein of unknown function (DUF1116) - - - 0.00000000000000000000000000000000000000000000000005299 179.0
TLS3_k127_7047666_3 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000000000000003275 161.0
TLS3_k127_7047666_4 YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the K09780 - - 0.0000000000000000000000000002367 117.0
TLS3_k127_7047666_5 nucleotidyltransferase activity K00984,K19279 - 2.7.7.47 0.0000000000000000000000001906 110.0
TLS3_k127_7052793_0 Pyrroloquinoline quinone biosynthesis protein PqqB K06136 - - 0.0000000000000000000000000000000000000000000000000000000002918 213.0
TLS3_k127_7052793_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000002839 162.0
TLS3_k127_7052793_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000002434 130.0
TLS3_k127_7055226_0 Non-ribosomal peptide synthetase modules and related - - - 0.0 1143.0
TLS3_k127_7055226_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 592.0
TLS3_k127_7055226_2 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000002381 225.0
TLS3_k127_7055226_4 lipase activity - - - 0.00000000000000000000001017 113.0
TLS3_k127_7055226_5 thioesterase involved in non-ribosomal peptide biosynthesis K01071 - 3.1.2.21 0.0000000114 57.0
TLS3_k127_7069774_0 PFAM Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005892 308.0
TLS3_k127_7069774_1 glycosyl transferase family 28 - - - 0.00000000000000000000000000000000000000003944 156.0
TLS3_k127_7069774_2 PFAM alpha beta hydrolase fold - - - 0.000000000000000000004147 101.0
TLS3_k127_7069774_3 Glycosyltransferase family 28 N-terminal domain - - - 0.0000000000001811 75.0
TLS3_k127_7069774_4 AAA domain - - - 0.000000001018 66.0
TLS3_k127_7077851_0 PFAM cytochrome c oxidase, subunit I K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000002437 208.0
TLS3_k127_7077851_1 PFAM electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000001537 199.0
TLS3_k127_7077851_2 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000000000000001911 193.0
TLS3_k127_7077851_3 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000002391 176.0
TLS3_k127_7077851_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000001072 148.0
TLS3_k127_7077851_5 2 iron, 2 sulfur cluster binding - - - 0.00000000000000000000007132 106.0
TLS3_k127_7077851_6 Protein of unknown function (DUF3307) - - - 0.0000000000001339 80.0
TLS3_k127_7077851_7 Protein conserved in bacteria K09796 - - 0.000004199 50.0
TLS3_k127_7079141_0 Sodium:sulfate symporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 504.0
TLS3_k127_7079141_1 thiamine transport K02063 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015234,GO:0015238,GO:0015893,GO:0016020,GO:0022857,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0045117,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071934,GO:0071944,GO:0072348,GO:0072531,GO:0090482,GO:1901474,GO:1901682 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007381 282.0
TLS3_k127_7079141_2 AcrB/AcrD/AcrF family K03296 - - 0.00000000000000000000000004641 111.0
TLS3_k127_7079850_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006841 251.0
TLS3_k127_7079850_1 Phage shock protein A K03969 - - 0.0000000000000000000000000000000000003598 150.0
TLS3_k127_7079850_2 - - - - 0.00000000000000000000000001452 115.0
TLS3_k127_7079850_3 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000659 102.0
TLS3_k127_7079850_4 PFAM PspC domain K03973 - - 0.00000000000000138 78.0
TLS3_k127_7084138_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 395.0
TLS3_k127_7084138_1 TFIIE alpha subunit - - - 0.000000000000000009174 87.0
TLS3_k127_7084138_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000002711 79.0
TLS3_k127_7101425_0 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 324.0
TLS3_k127_7101425_1 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 315.0
TLS3_k127_7101425_10 Protein of unknown function (DUF2877) - - - 0.0000000009634 69.0
TLS3_k127_7101425_3 PFAM Translin K07477 - - 0.0000000000000000000000000000000000000000000000000000000002414 209.0
TLS3_k127_7101425_4 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000003511 199.0
TLS3_k127_7101425_5 Cys-tRNA(Pro) hydrolase activity K03976 - - 0.00000000000000000000000000000000000000000001368 166.0
TLS3_k127_7101425_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000008374 145.0
TLS3_k127_7101425_7 FAD-dependent pyridine nucleotide-disulfide oxidoreductase - - - 0.0000000000000000000000000000000000002687 153.0
TLS3_k127_7101425_8 Protein of unknown function (DUF4230) - - - 0.000000000000000000000001569 112.0
TLS3_k127_7101425_9 Protein of unknown function (DUF503) K09764 - - 0.000000000000005703 79.0
TLS3_k127_7133226_0 DNA polymerase K02337,K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 544.0
TLS3_k127_7133226_1 - - - - 0.00000000000000000000000004308 113.0
TLS3_k127_7156126_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008945 264.0
TLS3_k127_7156126_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000478 186.0
TLS3_k127_7156126_2 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000003273 163.0
TLS3_k127_7156126_3 Translation initiation factor SUI1 K03113 - - 0.00000000000000000008626 93.0
TLS3_k127_7156126_4 alpha-L-arabinofuranosidase - - - 0.0000000000000009152 91.0
TLS3_k127_7156126_5 RHS Repeat - - - 0.00000004859 66.0
TLS3_k127_7166394_0 Phage tail tape measure protein TP901 K02005,K02022 - - 0.00000000000000000000000000000000000000000000000000000000001885 213.0
TLS3_k127_7200146_0 1,4-alpha-glucan branching enzyme K00700,K01236 - 2.4.1.18,3.2.1.141 2.74e-203 643.0
TLS3_k127_7200146_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 324.0
TLS3_k127_7216231_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 615.0
TLS3_k127_7219103_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 453.0
TLS3_k127_7219103_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004073 257.0
TLS3_k127_7227940_0 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 566.0
TLS3_k127_7227940_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 349.0
TLS3_k127_7227940_2 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000005842 193.0
TLS3_k127_7227940_3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000003407 57.0
TLS3_k127_7230362_0 McrBC 5-methylcytosine restriction system component K19147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 352.0
TLS3_k127_7230362_1 Protein conserved in bacteria K07011 - - 0.0000000000000000000000000000000000000000000000000000000002624 209.0
TLS3_k127_7230362_2 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000132 172.0
TLS3_k127_7230362_3 - - - - 0.00000000000000000008669 96.0
TLS3_k127_7236142_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.925e-300 931.0
TLS3_k127_7236142_1 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 313.0
TLS3_k127_7236142_2 Membrane protein, TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008717 244.0
TLS3_k127_7247090_0 Belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 591.0
TLS3_k127_7247090_1 Bacterial extracellular solute-binding protein K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 292.0
TLS3_k127_7247090_2 Binding-protein-dependent transport system inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000004518 175.0
TLS3_k127_7247090_3 (mono)amine oxidase - - - 0.000000000000000000001312 96.0
TLS3_k127_724937_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 580.0
TLS3_k127_724937_1 RNA 3'-terminal phosphate cyclase (RTC), insert domain K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 317.0
TLS3_k127_724937_2 COG3335 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000006658 186.0
TLS3_k127_724937_3 histidine kinase dimerisation and phosphoacceptor region K03406,K07673,K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000000006396 194.0
TLS3_k127_724937_4 PFAM DMSO reductase anchor subunit (DmsC) K07308 - - 0.000002066 54.0
TLS3_k127_7253208_0 Fructosamine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001153 286.0
TLS3_k127_7253208_1 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000002099 259.0
TLS3_k127_7253208_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000001074 233.0
TLS3_k127_7253208_4 Serine threonine protein kinase - - - 0.0000000002601 70.0
TLS3_k127_725633_0 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 361.0
TLS3_k127_725633_1 Chalcone and stilbene synthases, C-terminal domain K16167,K19580 - 2.3.1.233 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 359.0
TLS3_k127_725633_2 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007554 250.0
TLS3_k127_725633_3 PFAM Isoprenylcysteine carboxyl methyltransferase K16168 - - 0.00000000000000000000000000000000000000000000000002265 186.0
TLS3_k127_725633_4 L-allo-threonine aldolase activity - - - 0.00000000000000000000000000000004322 129.0
TLS3_k127_725633_5 Ankyrin repeat K10380,K10799 - 2.4.2.30 0.00000004872 62.0
TLS3_k127_725633_6 YcxB-like protein - - - 0.00003588 48.0
TLS3_k127_725679_0 COGs COG2382 Enterochelin esterase K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 329.0
TLS3_k127_725679_1 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000001588 190.0
TLS3_k127_7260039_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 499.0
TLS3_k127_7260039_1 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000002878 131.0
TLS3_k127_7260364_0 PFAM ABC transporter related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 370.0
TLS3_k127_7260364_1 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005839 294.0
TLS3_k127_7260364_2 secretion protein HlyD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001221 247.0
TLS3_k127_727068_0 FAD linked oxidase domain protein - - - 8.586e-196 624.0
TLS3_k127_727068_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 386.0
TLS3_k127_727068_2 sequence-specific DNA binding K03718 - - 0.0000000000000000000000000000000000001512 147.0
TLS3_k127_727068_3 COG1002 Type II restriction enzyme, methylase subunits - - - 0.00000002403 55.0
TLS3_k127_7271795_0 ABC transporter K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007519 332.0
TLS3_k127_7271795_1 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003251 274.0
TLS3_k127_7271795_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.00000000000001398 76.0
TLS3_k127_7272814_0 PFAM Short-chain dehydrogenase reductase SDR K00059,K00076 - 1.1.1.100,1.1.1.159 0.000000000000000000000000000000000000000000000000000000000000000000005023 244.0
TLS3_k127_7272814_1 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001869 234.0
TLS3_k127_7272814_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000008059 190.0
TLS3_k127_7272814_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000002886 157.0
TLS3_k127_7272814_4 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000008276 137.0
TLS3_k127_7272814_5 DinB family - - - 0.0000000000004198 72.0
TLS3_k127_7273281_0 PFAM carboxyl transferase - - - 9.453e-245 765.0
TLS3_k127_7273281_1 PFAM Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 557.0
TLS3_k127_7273281_2 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 401.0
TLS3_k127_7273281_3 cellular response to DNA damage stimulus - - - 0.00000000000000000000000000000000000000000000000000344 186.0
TLS3_k127_7273281_4 ChaB K06197 - - 0.000000000000000000000000000000006171 128.0
TLS3_k127_7273281_5 PFAM biotin lipoyl attachment domain-containing protein - - - 0.0000000000000000000000006731 111.0
TLS3_k127_7273281_6 topoisomerase K03168 - 5.99.1.2 0.00000004045 55.0
TLS3_k127_727566_0 PFAM Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 414.0
TLS3_k127_727566_1 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 385.0
TLS3_k127_727566_2 Evidence 5 No homology to any previously reported sequences K07156,K07245,K14166 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000002194 256.0
TLS3_k127_727566_3 ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000003219 173.0
TLS3_k127_727566_4 response to abiotic stimulus - - - 0.0000000000000000000000000000000008819 138.0
TLS3_k127_727566_5 - - - - 0.00000000000000003141 89.0
TLS3_k127_727566_6 - - - - 0.0002306 49.0
TLS3_k127_7290561_0 neuron death in response to oxidative stress K01173 - - 0.00000000000000000000000000000000000000007415 164.0
TLS3_k127_7303144_0 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000001881 220.0
TLS3_k127_7303144_1 cheY-homologous receiver domain K07658 - - 0.00000000000000000000000000002692 121.0
TLS3_k127_7309928_0 ABC transporter K06147 - - 1.847e-210 671.0
TLS3_k127_7309928_1 Aminotransferase class-V K01556 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 330.0
TLS3_k127_7329606_0 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 446.0
TLS3_k127_7329606_1 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000000000000000000000000001497 216.0
TLS3_k127_7329606_2 Protein of unknown function (DUF3179) - - - 0.00000000000000000000000000000000000000000000000000000006413 207.0
TLS3_k127_7329606_3 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000008068 176.0
TLS3_k127_7329606_4 PIN domain - - - 0.0000000000000000000000000000000000000000000001107 172.0
TLS3_k127_7329606_5 Glycogen recognition site of AMP-activated protein kinase - - - 0.000000000000000000000003807 107.0
TLS3_k127_7329606_6 - - - - 0.000000000001548 70.0
TLS3_k127_7335368_0 PFAM sodium hydrogen exchanger - - - 3.689e-283 887.0
TLS3_k127_7335368_1 Imidazolonepropionase and related amidohydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 320.0
TLS3_k127_7335368_2 PFAM Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000001162 233.0
TLS3_k127_7339176_0 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000002602 241.0
TLS3_k127_7339176_1 phosphorelay sensor kinase activity K01768,K02482,K02584,K07673,K10819 - 2.7.13.3,4.6.1.1 0.00000000000000000000000000000001426 144.0
TLS3_k127_7358471_1 P22_AR N-terminal domain - - - 0.0000001604 54.0
TLS3_k127_7382838_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 381.0
TLS3_k127_7382838_1 Protein-disulfide isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005762 295.0
TLS3_k127_7382838_2 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000004561 109.0
TLS3_k127_7382838_3 O-methyltransferase activity - - - 0.00000000000000001672 83.0
TLS3_k127_7400422_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 452.0
TLS3_k127_7400422_1 ATPases associated with a variety of cellular activities K02000 - 3.6.3.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 383.0
TLS3_k127_7400422_2 COG4176 ABC-type proline glycine betaine transport system, permease component K02001 - - 0.0000000000000000000000000000000000000000008635 166.0
TLS3_k127_7402325_0 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 485.0
TLS3_k127_7402325_1 Alpha beta hydrolase K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000003427 171.0
TLS3_k127_7402325_2 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000006703 138.0
TLS3_k127_7402325_3 MaoC like domain - - - 0.00000000000000000000000000000006008 128.0
TLS3_k127_7406741_0 diaminopimelate decarboxylase activity K01585,K01586 - 4.1.1.19,4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 329.0
TLS3_k127_7406741_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 312.0
TLS3_k127_7406741_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 292.0
TLS3_k127_7406741_3 GyrI-like small molecule binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003248 264.0
TLS3_k127_7406741_4 PFAM von Willebrand factor type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003354 265.0
TLS3_k127_7406741_5 helix_turn_helix, arabinose operon control protein K13652 - - 0.0000000000000003413 81.0
TLS3_k127_7406741_6 NMT1/THI5 like - - - 0.00000000001987 77.0
TLS3_k127_7421489_0 Ig-like domain from next to BRCA1 gene - - - 0.0000000000000000000000000000001032 137.0
TLS3_k127_7421489_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000002534 87.0
TLS3_k127_7421735_0 Leucine rich repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000001181 239.0
TLS3_k127_7421735_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000004934 182.0
TLS3_k127_7421735_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000005666 149.0
TLS3_k127_7421735_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000006204 116.0
TLS3_k127_7421735_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000004603 53.0
TLS3_k127_7421871_0 Glycosyl hydrolases family 39 K01198 - 3.2.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 591.0
TLS3_k127_7421871_1 Putative glucoamylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 540.0
TLS3_k127_7421871_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 415.0
TLS3_k127_7421871_3 PFAM Ribonuclease BN-like family K07058 - - 0.00000000000000000000000000000000000000000000000000000000000001242 223.0
TLS3_k127_7421871_4 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000002305 177.0
TLS3_k127_7425354_0 Cellobiose phosphorylase K00702,K13688,K18675 - 2.4.1.20,2.4.1.280 0.0 1045.0
TLS3_k127_7425354_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 431.0
TLS3_k127_7425354_2 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 312.0
TLS3_k127_744416_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000004521 223.0
TLS3_k127_744416_1 Histidine kinase K07777 - 2.7.13.3 0.0000000000000000000000001619 122.0
TLS3_k127_744416_2 Predicted membrane protein (DUF2085) - - - 0.000000000000000000002129 98.0
TLS3_k127_745282_0 TIGRFAM threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 464.0
TLS3_k127_745282_1 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 409.0
TLS3_k127_745282_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000007986 198.0
TLS3_k127_745282_3 endonuclease exonuclease phosphatase - - - 0.00000000000000000000000000000000002075 144.0
TLS3_k127_7466302_0 tRNA wobble cytosine modification - - - 0.00000000000000000000000000000000000000000000002836 187.0
TLS3_k127_7466302_1 tRNA wobble cytosine modification - - - 0.000000000000000000000000009069 121.0
TLS3_k127_7478076_0 Alcohol dehydrogenase GroES domain protein - - - 5.326e-200 629.0
TLS3_k127_7478076_1 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 359.0
TLS3_k127_7478076_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 294.0
TLS3_k127_7478076_3 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001114 278.0
TLS3_k127_7479613_0 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 291.0
TLS3_k127_7479613_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000001816 233.0
TLS3_k127_7479613_2 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000005808 196.0
TLS3_k127_7479613_3 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.00000000000000000000000000000125 124.0
TLS3_k127_7479613_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000003182 58.0
TLS3_k127_748741_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 500.0
TLS3_k127_748741_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009053 411.0
TLS3_k127_748741_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 410.0
TLS3_k127_748741_3 PFAM Glycosyl transferase, group 1 K13668 GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.346 0.000000000000000000000000000000000000000003643 168.0
TLS3_k127_748741_4 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000003349 159.0
TLS3_k127_748741_5 FecR protein - - - 0.00000000000000000000000000001199 138.0
TLS3_k127_748741_6 ECF sigma factor K03088 - - 0.0000000000000000000000000001039 122.0
TLS3_k127_748741_7 PFAM Polysaccharide biosynthesis protein - - - 0.0000000000000000000001374 112.0
TLS3_k127_748741_8 methyltransferase - - - 0.0000000000001 79.0
TLS3_k127_748741_9 Tfp pilus assembly protein tip-associated adhesin PilY1 K02674 - - 0.0002152 55.0
TLS3_k127_7487529_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000005409 232.0
TLS3_k127_7496117_0 intracellular signal transduction - - - 1.634e-252 809.0
TLS3_k127_7498074_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 292.0
TLS3_k127_7498074_1 periplasmic protein (DUF2233) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003132 285.0
TLS3_k127_7498074_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000003466 189.0
TLS3_k127_7498074_3 Belongs to the SUA5 family K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.00000000000000000000000000000000001933 143.0
TLS3_k127_7498074_4 Bacterial SH3 domain - - - 0.0004983 49.0
TLS3_k127_7518606_0 NADPH:quinone reductase activity K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 404.0
TLS3_k127_7518606_1 MgtE intracellular N domain K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006639 336.0
TLS3_k127_7518606_2 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 GO:0002252,GO:0002376,GO:0003674,GO:0003824,GO:0006464,GO:0006476,GO:0006807,GO:0006935,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033558,GO:0034979,GO:0034983,GO:0035601,GO:0036048,GO:0036049,GO:0036055,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071704,GO:0098542,GO:0098732,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 309.0
TLS3_k127_7518606_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000001388 234.0
TLS3_k127_7518606_4 Psort location Cytoplasmic, score K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000003309 173.0
TLS3_k127_7518606_5 Putative membrane peptidase family (DUF2324) - - - 0.0000000000000000000000000000000000000000000000689 180.0
TLS3_k127_7518606_6 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000004758 144.0
TLS3_k127_7518606_7 peptidase C60 sortase A and B K07284 - 3.4.22.70 0.000000000000000000000000000000003332 138.0
TLS3_k127_7518606_8 Histidine kinase - - - 0.000000002709 63.0
TLS3_k127_7518978_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.961e-206 657.0
TLS3_k127_7518978_1 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 473.0
TLS3_k127_7518978_2 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000001699 233.0
TLS3_k127_7518978_3 Major facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000152 174.0
TLS3_k127_7518978_4 regulation of single-species biofilm formation K02342,K03763,K13573 - 2.7.7.7 0.0000000000000000000000000000000000007868 153.0
TLS3_k127_7518978_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000004537 104.0
TLS3_k127_7518978_6 Protein of unknown function (DUF448) K07742 - - 0.00000000000000000002097 96.0
TLS3_k127_7519593_0 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 542.0
TLS3_k127_7519593_1 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 377.0
TLS3_k127_7519593_2 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 337.0
TLS3_k127_7519593_3 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000004577 234.0
TLS3_k127_7519593_4 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000001543 192.0
TLS3_k127_7519593_5 dehydratase K17865,K19659 - 4.2.1.119,4.2.1.55 0.00000000000000000000000000000001828 130.0
TLS3_k127_7522132_0 pyridine nucleotide-disulphide oxidoreductase K00362,K07001 - 1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 433.0
TLS3_k127_7522132_1 MFS_1 like family K08151,K08153 - - 0.00000000000000000000000000000000000000000000000000003833 203.0
TLS3_k127_7522132_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000167 165.0
TLS3_k127_7522132_3 acetyltransferase - - - 0.00000000000000000000000000000000000002223 148.0
TLS3_k127_7522132_4 Transmembrane secretion effector - - - 0.000000000000000000000000000000000001694 145.0
TLS3_k127_7522132_5 NmrA-like family - - - 0.00000000000000000000000000000368 123.0
TLS3_k127_7522132_6 - - - - 0.00000001376 65.0
TLS3_k127_7535959_0 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 287.0
TLS3_k127_7535959_1 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000008643 200.0
TLS3_k127_7535959_3 transglycosylase K08309 - - 0.000000001874 68.0
TLS3_k127_7535959_4 Alpha/beta hydrolase family - - - 0.0000007935 58.0
TLS3_k127_7535959_5 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) - - - 0.00006729 48.0
TLS3_k127_7536482_0 ABC transporter, transmembrane region K06147 - - 7.963e-216 685.0
TLS3_k127_7536482_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 609.0
TLS3_k127_7536482_2 SWIM zinc finger - - - 0.000000000000000000000000000000000000000000000000000000000007674 220.0
TLS3_k127_7536482_3 Shikimate kinase - - - 0.0000000000000000000000000000000000000000000000000005595 190.0
TLS3_k127_7536482_4 adenylate kinase activity - - - 0.000000000000000000000000000000000000000000000000145 186.0
TLS3_k127_7536482_5 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000001545 162.0
TLS3_k127_7538725_0 PFAM mannose-6-phosphate isomerase type I K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 331.0
TLS3_k127_7538725_1 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001852 298.0
TLS3_k127_7538725_2 phosphorelay signal transduction system K07670 - - 0.00000000000000000000000000000000000000008638 153.0
TLS3_k127_7541834_0 PFAM Patatin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000724 281.0
TLS3_k127_7541834_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000001261 260.0
TLS3_k127_7541834_2 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000000000000000003347 249.0
TLS3_k127_7541834_3 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000000000000000002633 227.0
TLS3_k127_7541834_4 PHP-associated - - - 0.0000000000000000000000000000000000000000000000000000000007689 205.0
TLS3_k127_7541834_5 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000001614 165.0
TLS3_k127_7541834_6 Belongs to the UPF0337 (CsbD) family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000176 96.0
TLS3_k127_754891_0 lactate racemase activity K22373 - 5.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 449.0
TLS3_k127_754891_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003696 270.0
TLS3_k127_754891_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004252 252.0
TLS3_k127_754891_3 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000003452 208.0
TLS3_k127_754891_4 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000003909 189.0
TLS3_k127_754891_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000002078 186.0
TLS3_k127_754891_6 Shikimate kinase K00851 - 2.7.1.12 0.00000000000000000000000000000000000000000001851 166.0
TLS3_k127_754891_7 domain, Protein - - - 0.0000000000000000000000000000000000008078 153.0
TLS3_k127_7550190_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K14090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 552.0
TLS3_k127_7550190_1 quinone binding K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 419.0
TLS3_k127_7550190_2 4Fe-4S binding domain K14091 - - 0.0000000000000000000000000000000000000000000000002579 184.0
TLS3_k127_7550190_3 hydrogenase maturation protease K08315 - 3.4.23.51 0.0000000000000000000001239 103.0
TLS3_k127_7553150_0 TIGRFAM molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 446.0
TLS3_k127_7553150_1 PFAM glycosyl transferase family 39 - - - 0.000000000000002447 85.0
TLS3_k127_7553150_2 - - - - 0.000000000008427 71.0
TLS3_k127_7553150_3 - - - - 0.0000008277 61.0
TLS3_k127_7553150_4 Lysylphosphatidylglycerol synthase TM region - - - 0.000001008 61.0
TLS3_k127_7554463_0 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 399.0
TLS3_k127_7554463_1 Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000001504 231.0
TLS3_k127_7554463_2 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000009009 196.0
TLS3_k127_7554463_3 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000006941 159.0
TLS3_k127_7569458_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000002915 176.0
TLS3_k127_7569458_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.00002798 48.0
TLS3_k127_7570523_0 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008733 393.0
TLS3_k127_7570523_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K00446 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 369.0
TLS3_k127_7570523_2 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000005845 66.0
TLS3_k127_7572048_0 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009833 550.0
TLS3_k127_7572048_1 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000002884 174.0
TLS3_k127_7572048_2 Cellulose biosynthesis protein BcsQ K02282 - - 0.0000000000000000000000000000000000000000001144 173.0
TLS3_k127_7572048_3 Two component transcriptional regulator, winged helix family K07667 - - 0.000000000000000000000000000004504 123.0
TLS3_k127_7572048_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000003386 74.0
TLS3_k127_7587495_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1244.0
TLS3_k127_7587495_1 beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000009993 168.0
TLS3_k127_7587495_2 PFAM regulatory protein AsnC Lrp family - - - 0.00000000000000000000000000000104 124.0
TLS3_k127_7587495_3 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.00000000001628 65.0
TLS3_k127_7616089_0 ABC transporter K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001618 278.0
TLS3_k127_7616089_1 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.00000000000000000000000000000000000000000000000000000000002632 209.0
TLS3_k127_7616089_2 transmembrane transport K09696 - - 0.000000000000000000000000000000112 138.0
TLS3_k127_7616089_3 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.000000009564 56.0
TLS3_k127_7616089_4 FHA domain - - - 0.0000004109 63.0
TLS3_k127_7622853_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000001099 218.0
TLS3_k127_7622853_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000004808 165.0
TLS3_k127_7622853_2 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000242 149.0
TLS3_k127_7630466_0 NAD-dependent epimerase dehydratase K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 344.0
TLS3_k127_7630466_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000005178 190.0
TLS3_k127_7630466_2 transaminase activity K00375 - - 0.0000000000000000000000000000000000000000004608 159.0
TLS3_k127_7630466_3 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000007014 149.0
TLS3_k127_7639038_0 Rieske-like [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 608.0
TLS3_k127_7639038_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 496.0
TLS3_k127_7639038_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000003101 240.0
TLS3_k127_7639038_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000001676 209.0
TLS3_k127_7639038_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000008152 201.0
TLS3_k127_7639038_5 PIN domain - - - 0.000000000000000000000000000000000000000000000001409 177.0
TLS3_k127_7639038_6 HicB family - - - 0.0000000000000000000000000001939 119.0
TLS3_k127_7639038_7 Protein of unknown function (DUF512) - - - 0.00000004992 58.0
TLS3_k127_7645356_0 Two component transcriptional regulator, winged helix family K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 332.0
TLS3_k127_7645356_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000000356 197.0
TLS3_k127_7645356_2 PFAM von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000003426 181.0
TLS3_k127_7645356_3 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000002445 103.0
TLS3_k127_7645356_4 - - - - 0.00000000000000000002173 92.0
TLS3_k127_7656952_0 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000004326 213.0
TLS3_k127_7656952_1 GNAT acetyltransferase - - - 0.000000000000000000000000000000007533 138.0
TLS3_k127_7656952_2 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.00000000000000000001257 95.0
TLS3_k127_7672532_0 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 383.0
TLS3_k127_7672532_1 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000001827 207.0
TLS3_k127_7672532_2 PFAM response regulator receiver - - - 0.0000000000000000000000000007303 117.0
TLS3_k127_7673364_0 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000005494 121.0
TLS3_k127_7673364_1 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000000004636 112.0
TLS3_k127_7673364_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.00000000000000000000001129 102.0
TLS3_k127_7673364_3 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000002709 95.0
TLS3_k127_7673364_4 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000001553 95.0
TLS3_k127_7695533_0 Psort location CytoplasmicMembrane, score K00368 - 1.7.2.1 0.00000000000000000000000000000000000000009102 174.0
TLS3_k127_7695533_1 methyltransferase - - - 0.00000000000000000000304 104.0
TLS3_k127_7706373_0 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 1.65e-268 854.0
TLS3_k127_7706373_1 Alpha-amylase domain K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 464.0
TLS3_k127_7706373_2 Semialdehyde dehydrogenase, NAD binding domain K00133,K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0030312,GO:0036094,GO:0040007,GO:0043891,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071944,GO:0097159,GO:1901265,GO:1901363 1.2.1.11,1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 402.0
TLS3_k127_7706373_3 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 351.0
TLS3_k127_7706373_4 S23 ribosomal protein - - - 0.0000000000504 63.0
TLS3_k127_7725426_0 PFAM Prolyl oligopeptidase family - - - 1.949e-273 855.0
TLS3_k127_7725426_1 PFAM glycosyl transferase, family 51 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 552.0
TLS3_k127_7725426_2 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 412.0
TLS3_k127_7725426_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000004896 252.0
TLS3_k127_7725426_4 Thiopurine S-methyltransferase (TPMT) K00569 - 2.1.1.67 0.00000000000000000000000000000000000000003289 160.0
TLS3_k127_7725426_5 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000001471 148.0
TLS3_k127_7725426_6 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000002265 100.0
TLS3_k127_7725426_7 Membrane - - - 0.000000000004723 80.0
TLS3_k127_7728358_0 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000009431 260.0
TLS3_k127_7728358_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000002067 208.0
TLS3_k127_7728358_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000002393 191.0
TLS3_k127_7728358_3 PFAM Acetyltransferase (GNAT) family K00657 - 2.3.1.57 0.00000000000000000000000000000000000000000001043 167.0
TLS3_k127_7728358_4 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000003234 112.0
TLS3_k127_7728358_5 VanZ like family - - - 0.0000000000000006125 83.0
TLS3_k127_7728358_6 Phosphodiester glycosidase - - - 0.00000001419 66.0
TLS3_k127_7728358_7 oxidoreductase activity K08282,K16260 - 2.7.11.1 0.00000002589 64.0
TLS3_k127_7728358_8 Zinc finger domain - - - 0.0000872 51.0
TLS3_k127_7753685_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 424.0
TLS3_k127_7753685_1 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 351.0
TLS3_k127_7753685_2 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000002599 194.0
TLS3_k127_7753685_3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000001146 127.0
TLS3_k127_7753685_4 Thioesterase domain - - - 0.000000000000000000000000000001517 130.0
TLS3_k127_7753685_5 - - - - 0.000000000000000000000000004814 114.0
TLS3_k127_7753685_6 Protein of unknown function (DUF433) - - - 0.000000000000000000004336 97.0
TLS3_k127_7753685_7 PFAM LmbE family protein K18455 - 3.5.1.115 0.0000000000000002846 81.0
TLS3_k127_7760317_0 PFAM ABC transporter transmembrane region K06147,K18890 - - 7.152e-216 682.0
TLS3_k127_7760317_1 PFAM ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 432.0
TLS3_k127_7772780_0 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K12452,K13328 - 1.17.1.1,4.2.1.164 2.774e-201 637.0
TLS3_k127_7772780_1 Belongs to the peptidase S16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 566.0
TLS3_k127_7772780_2 Protoporphyrinogen oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 467.0
TLS3_k127_7772780_3 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 341.0
TLS3_k127_7772780_4 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000002702 112.0
TLS3_k127_7772780_5 - - - - 0.00000000003605 67.0
TLS3_k127_7773813_0 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 538.0
TLS3_k127_7773813_1 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 472.0
TLS3_k127_7773813_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 404.0
TLS3_k127_7793613_0 Arabinogalactan endo-beta-1,4-galactanase K01224 - 3.2.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 331.0
TLS3_k127_7815184_0 Phosphotransferase enzyme family K17910 - 2.7.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000001441 268.0
TLS3_k127_7815184_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001953 250.0
TLS3_k127_7815184_2 homoserine kinase type II (protein kinase fold) - - - 0.0000000000000000000000000000000000000000000000000000000000000006367 231.0
TLS3_k127_7815184_3 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000003704 176.0
TLS3_k127_7815184_4 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000006803 145.0
TLS3_k127_7815184_5 Acetyltransferase (GNAT) family - - - 0.00000000000000001362 88.0
TLS3_k127_7817452_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 436.0
TLS3_k127_7817452_1 PUCC protein K08226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 370.0
TLS3_k127_7817452_2 AAA ATPase domain - - - 0.0000000000000009038 91.0
TLS3_k127_7823593_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 306.0
TLS3_k127_7823593_1 Cytochrome c - - - 0.00000000000000000000000000000000000000002136 153.0
TLS3_k127_7823593_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000587 65.0
TLS3_k127_7829759_0 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 429.0
TLS3_k127_7829759_1 Belongs to the ABC transporter superfamily K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 342.0
TLS3_k127_7829759_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K13891,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000003172 232.0
TLS3_k127_7829759_3 nitrogen compound transport K02033,K02034,K15581 - - 0.0000000000000000000000000000000000000000000000000004211 196.0
TLS3_k127_7836131_0 Amidohydrolase family K18456 - 3.5.4.32 1.207e-194 619.0
TLS3_k127_7836131_1 PFAM Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 333.0
TLS3_k127_7836131_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000133 281.0
TLS3_k127_7836131_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000003077 222.0
TLS3_k127_7836131_4 - - - - 0.00000000000000000000000000002645 123.0
TLS3_k127_7836131_5 PFAM Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.0000000000000000006842 92.0
TLS3_k127_7836131_6 Peptidase M10 serralysin C terminal K01406 - 3.4.24.40 0.000000000000001844 90.0
TLS3_k127_7839668_0 Horizontally Transferred TransMembrane Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 501.0
TLS3_k127_7839668_1 Prolyl oligopeptidase family - - - 0.00003956 55.0
TLS3_k127_7842256_0 pathogenesis K21471,K21687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000251 289.0
TLS3_k127_7842256_1 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000242 232.0
TLS3_k127_7842256_2 Threonyl alanyl tRNA synthetase SAD K07050 - - 0.000000000000000000000000000000000000000008363 159.0
TLS3_k127_7842256_3 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000001027 151.0
TLS3_k127_7842256_4 Bacterial transcription activator, effector binding domain - - - 0.0000000000000000000000000000004487 128.0
TLS3_k127_7842256_5 Transcriptional regulator K13653 - - 0.000000000000000000000203 106.0
TLS3_k127_7842256_6 anti-sigma regulatory factor, serine threonine protein kinase K04757 - 2.7.11.1 0.0000000000000004143 83.0
TLS3_k127_7842256_7 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.00006582 50.0
TLS3_k127_7842256_8 STAS domain - - - 0.00007601 50.0
TLS3_k127_7842256_9 conserved protein (DUF2267) - - - 0.00008979 50.0
TLS3_k127_7847585_0 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 455.0
TLS3_k127_7847585_1 PFAM oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 453.0
TLS3_k127_7847585_2 Beta-lactamase K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 352.0
TLS3_k127_7847585_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000001542 72.0
TLS3_k127_7848419_0 Sulfate transporter K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 580.0
TLS3_k127_7848419_1 PFAM Rhodanese domain protein - - - 0.000000000000000000000000000000004862 131.0
TLS3_k127_7856276_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 420.0
TLS3_k127_7856276_1 UbiA prenyltransferase family K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 362.0
TLS3_k127_7856276_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000002754 69.0
TLS3_k127_7859046_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000152 263.0
TLS3_k127_7859046_1 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000001123 146.0
TLS3_k127_7859046_2 Lysin motif - - - 0.0001648 50.0
TLS3_k127_7861048_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 389.0
TLS3_k127_7861048_1 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 313.0
TLS3_k127_7861048_2 SMART regulatory protein, ArsR - - - 0.00000000000005641 81.0
TLS3_k127_7868612_0 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 471.0
TLS3_k127_7868612_1 UDP-glucose 4-epimerase activity K01784,K08679,K17947 - 5.1.3.2,5.1.3.25,5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007081 424.0
TLS3_k127_7868612_10 - - - - 0.00000000000000000000000121 119.0
TLS3_k127_7868612_11 DNA binding - - - 0.000000000000000000008414 95.0
TLS3_k127_7868612_2 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 329.0
TLS3_k127_7868612_3 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 299.0
TLS3_k127_7868612_4 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008445 273.0
TLS3_k127_7868612_5 Helix-turn-helix XRE-family like proteins K18831 - - 0.000000000000000000000000000000000000000000000002308 176.0
TLS3_k127_7868612_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000004899 163.0
TLS3_k127_7868612_7 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.0000000000000000000000000000000000000001999 151.0
TLS3_k127_7868612_8 response to stress - - - 0.0000000000000000000000000000000009851 138.0
TLS3_k127_7868612_9 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000000000000000000000001258 117.0
TLS3_k127_7882010_0 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 468.0
TLS3_k127_7882010_1 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000109 165.0
TLS3_k127_7891402_0 Sodium/hydrogen exchanger family - - - 2.846e-246 778.0
TLS3_k127_7891402_1 component I K01665,K03342 - 2.6.1.85,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 383.0
TLS3_k127_7891402_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 318.0
TLS3_k127_7891402_3 - - - - 0.0000000000000000000421 95.0
TLS3_k127_7899015_0 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 508.0
TLS3_k127_7899015_1 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 308.0
TLS3_k127_7899015_2 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 325.0
TLS3_k127_7899015_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000009227 270.0
TLS3_k127_7899015_4 PFAM cytochrome c oxidase, subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000005702 254.0
TLS3_k127_7899015_5 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.0000000000000000000000000000000000000000000000000000000000000000009435 238.0
TLS3_k127_7899015_6 mitochondrial respiratory chain complex IV assembly K14998 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 - 0.0000000000000000000000000000000993 134.0
TLS3_k127_7899015_7 - - - - 0.0000000001797 69.0
TLS3_k127_7911955_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 4.996e-230 726.0
TLS3_k127_7911955_1 PFAM oxidoreductase domain protein - - - 2.895e-217 679.0
TLS3_k127_7911955_2 AP endonuclease family 2 C terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006739 243.0
TLS3_k127_7911955_3 negative regulation of transcription, DNA-templated K10947 - - 0.00000000000000000000000000000949 122.0
TLS3_k127_7911955_4 Hep Hag repeat protein - - - 0.0000000000000000000000003835 120.0
TLS3_k127_7911955_5 - - - - 0.0000000000000001031 88.0
TLS3_k127_7911955_6 - - - - 0.0000001793 59.0
TLS3_k127_7919446_1 dihydrofolate reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 304.0
TLS3_k127_7919446_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000009644 202.0
TLS3_k127_7929169_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 458.0
TLS3_k127_7929169_1 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001177 283.0
TLS3_k127_7929169_2 response to abiotic stimulus K01971,K03086,K06867,K06886 GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006996,GO:0007010,GO:0007015,GO:0008092,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030029,GO:0030036,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044877,GO:0046983,GO:0051015,GO:0051259,GO:0065003,GO:0071840,GO:0097435 6.5.1.1 0.0000000000000000000000000000000000004967 147.0
TLS3_k127_7930555_0 Proline racemase K01777 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016855,GO:0018112,GO:0019752,GO:0036361,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047661,GO:0050346,GO:0071704,GO:1901564 5.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 505.0
TLS3_k127_7930555_1 glycine d-amino acid oxidases (Deaminating) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003385 240.0
TLS3_k127_7930555_2 aminoglycoside hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.0000000000000000000000000000000000000000000000000001074 190.0
TLS3_k127_7935513_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 3.2e-206 664.0
TLS3_k127_7935513_1 Bacterial extracellular solute-binding protein K15770 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007647 407.0
TLS3_k127_7935513_2 transmembrane transport K02025,K05814,K10109,K10118,K10237,K10241,K15771,K17235,K17242,K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 318.0
TLS3_k127_7935513_3 Belongs to the glycosyl hydrolase 13 family - - - 0.000000000000000000004842 108.0
TLS3_k127_7935513_4 Transcriptional regulator, MarR family - - - 0.0000000000000005264 84.0
TLS3_k127_7938400_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 346.0
TLS3_k127_7938400_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003867 273.0
TLS3_k127_7938400_2 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003773 258.0
TLS3_k127_7952344_0 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region - - - 0.0003061 43.0
TLS3_k127_7956080_1 PFAM Phosphoglycerate mutase K02226,K22305 - 3.1.3.3,3.1.3.73 0.0000000000000000000000000000000000001418 151.0
TLS3_k127_7956080_2 Methyltransferase domain - - - 0.00000000000000000000000000005384 124.0
TLS3_k127_7956080_3 PFAM restriction endonuclease K07448 - - 0.0000000000000000000003252 98.0
TLS3_k127_7968042_0 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 353.0
TLS3_k127_7968042_1 Protein of unknown function (DUF4012) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002 271.0
TLS3_k127_7998621_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1047.0
TLS3_k127_7998621_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 9.99e-226 717.0
TLS3_k127_7998621_2 FGGY family of carbohydrate kinases, N-terminal domain K00848,K00879,K01813 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008993,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019200,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046835,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901575 2.7.1.5,2.7.1.51,5.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 522.0
TLS3_k127_7998621_3 Transcriptional regulator ArsR family - - - 0.0000000000000000000000000000000000000006034 150.0
TLS3_k127_7998621_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000001273 140.0
TLS3_k127_7999994_0 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000003371 198.0
TLS3_k127_7999994_1 Nitrate reductase delta subunit - - - 0.000000000000000000000000000000000000000000000001217 187.0
TLS3_k127_7999994_2 PFAM YeeE YedE family (DUF395) K07112 - - 0.0000000000000000000000000000000000000000000002853 172.0
TLS3_k127_7999994_3 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000003086 168.0
TLS3_k127_7999994_4 PFAM YeeE YedE family (DUF395) K07112 - - 0.000000000000000000000000000000000000000001496 161.0
TLS3_k127_8005792_0 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007108 286.0
TLS3_k127_8005792_1 S-adenosyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000001558 204.0
TLS3_k127_8005792_2 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000001681 186.0
TLS3_k127_8005792_3 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000003491 135.0
TLS3_k127_8005792_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000005064 62.0
TLS3_k127_8011593_0 cellulase activity K01730 - 4.2.2.6 0.000000000000000000000000000000000001087 157.0
TLS3_k127_8011593_1 ASPIC and UnbV - - - 0.000001662 59.0
TLS3_k127_803727_0 PFAM FAD dependent oxidoreductase K09471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005543 383.0
TLS3_k127_803727_1 Vitamin k epoxide reductase - - - 0.00000000000000000000000000000000000002161 147.0
TLS3_k127_803727_2 protein conserved in bacteria containing thioredoxin-like domain - - - 0.00000000000000000000000000000001846 135.0
TLS3_k127_804821_0 Protein of unknown function (DUF1349) K09702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 286.0
TLS3_k127_804821_1 PFAM bifunctional deaminase-reductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 283.0
TLS3_k127_804821_2 An automated process has identified a potential problem with this gene model - - - 0.0000000000000000000000000000000000000000000000002803 184.0
TLS3_k127_8055329_0 Belongs to the peptidase S8 family - - - 5.752e-227 725.0
TLS3_k127_8055329_1 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000952 240.0
TLS3_k127_8064659_0 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 324.0
TLS3_k127_8064659_1 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.000000000000000000000000000000000000000000000000000001165 199.0
TLS3_k127_8064659_2 Methyltransferase FkbM domain - - - 0.000000000000000000000321 108.0
TLS3_k127_8101257_0 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 379.0
TLS3_k127_8101257_1 Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000000000000000000000000001543 226.0
TLS3_k127_8101257_2 AAA domain - - - 0.00000000000000000000000000000002243 133.0
TLS3_k127_8101257_3 Putative transposase DNA-binding domain K07496 - - 0.00000000002488 70.0
TLS3_k127_810790_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 339.0
TLS3_k127_810790_1 TIGRFAM phosphate binding protein - - - 0.00000000000000000000000000000000005309 144.0
TLS3_k127_8109742_0 PFAM isocitrate lyase and phosphorylmutase K01637 - 4.1.3.1 3.055e-209 658.0
TLS3_k127_8109742_1 transcriptional activator domain - - - 0.00000000000000001501 87.0
TLS3_k127_8109742_2 Belongs to the malate synthase family K01638 - 2.3.3.9 0.000006361 48.0
TLS3_k127_812098_0 Belongs to the ALAD family K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 456.0
TLS3_k127_812098_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 426.0
TLS3_k127_812098_2 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009695 377.0
TLS3_k127_812098_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000252 289.0
TLS3_k127_812098_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006306 289.0
TLS3_k127_812098_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000005301 249.0
TLS3_k127_812098_6 Uroporphyrinogen-III synthase HemD K02303,K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000006007 149.0
TLS3_k127_8121097_0 Glycogen debranching enzyme, glucanotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 430.0
TLS3_k127_8121097_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000001201 174.0
TLS3_k127_8121097_2 Protein of unknown function (DUF952) - - - 0.00000000000000000000000000000000000007642 145.0
TLS3_k127_8121097_3 Bacterial PH domain - - - 0.000000000000000000000000000001996 138.0
TLS3_k127_8121097_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000002004 93.0
TLS3_k127_8121097_5 cell division protein FtsK K03466 - - 0.0000009189 52.0
TLS3_k127_8124050_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000005127 138.0
TLS3_k127_8124156_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 550.0
TLS3_k127_8124156_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 338.0
TLS3_k127_8124156_2 lysine exporter protein (LysE YggA) K06600,K06895 - - 0.00000000000000008774 90.0
TLS3_k127_8125676_0 PFAM ABC transporter related K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 515.0
TLS3_k127_8125676_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 349.0
TLS3_k127_8125676_2 Transcriptional regulator, LacI family K02529 - - 0.000009475 49.0
TLS3_k127_8125879_0 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000003955 207.0
TLS3_k127_8125879_2 SMART Glycosyl hydrolase, family 13, subfamily, catalytic K00701 - 2.4.1.19 0.0000000000002651 72.0
TLS3_k127_8127705_0 Peptidase C39 family K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 344.0
TLS3_k127_8127705_1 Helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000002552 189.0
TLS3_k127_8127705_2 IMG reference gene - - - 0.0000000000000000000000000000000000000000009976 173.0
TLS3_k127_8140116_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 5.651e-302 972.0
TLS3_k127_8140116_1 Signal Transduction Histidine Kinase - - - 0.00000000000000000000000000000000000000000166 159.0
TLS3_k127_8140116_2 photosynthesis - - - 0.00000000000000000000000000000000000000007018 154.0
TLS3_k127_8142493_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 410.0
TLS3_k127_8142493_1 lactoylglutathione lyase activity K01239 - 3.2.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001773 255.0
TLS3_k127_8142493_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000002825 156.0
TLS3_k127_8143518_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006462 275.0
TLS3_k127_8143518_1 DNA polymerase III - - - 0.0000000000000000000000000000000000000000000000000000000000001304 222.0
TLS3_k127_8143518_2 regulation of response to stimulus - - - 0.00000000000000000000000000000000000000000000000000002171 213.0
TLS3_k127_8143518_3 Acetyltransferase GNAT family - - - 0.0000000000000000000000000000000002672 143.0
TLS3_k127_8143518_4 PFAM HD domain K06950 - - 0.0000000000000001189 88.0
TLS3_k127_8143518_5 response to heat K03668,K09914 - - 0.0000000000000003981 93.0
TLS3_k127_8143518_6 S-layer homology domain - - - 0.0000001384 65.0
TLS3_k127_8160631_0 PFAM Glycosyl transferase family 2 K00694 - 2.4.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 375.0
TLS3_k127_8160631_1 PFAM peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000356 204.0
TLS3_k127_8160631_2 Protein of unknown function (DUF2089) - - - 0.00000000000000000000000000003356 120.0
TLS3_k127_8160631_3 Bacterial protein of unknown function (DUF951) - - - 0.0000000000000000001653 89.0
TLS3_k127_8160631_4 Putative adhesin - - - 0.000000851 59.0
TLS3_k127_8160968_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 413.0
TLS3_k127_8160968_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 343.0
TLS3_k127_8160968_2 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004969 274.0
TLS3_k127_8160968_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000002348 189.0
TLS3_k127_8160968_4 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000001644 164.0
TLS3_k127_8160968_5 SnoaL-like domain - - - 0.00000000000002116 82.0
TLS3_k127_8160968_6 - - - - 0.00000007353 62.0
TLS3_k127_8168904_0 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 473.0
TLS3_k127_8168904_1 trisaccharide binding - - - 0.00000000000000000000004514 99.0
TLS3_k127_8168904_2 membrane-bound metal-dependent K07038 - - 0.00000000000000007295 87.0
TLS3_k127_8170592_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000746 258.0
TLS3_k127_8170592_1 belongs to the PRA-CH family K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000005282 153.0
TLS3_k127_8170592_2 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000000000000002349 113.0
TLS3_k127_8170592_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000001021 101.0
TLS3_k127_8170592_4 Protein phosphatase 2A homologues, catalytic domain. K06269 - 3.1.3.16 0.0000000000008124 79.0
TLS3_k127_8174230_0 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 379.0
TLS3_k127_8174230_1 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 359.0
TLS3_k127_8174230_2 - K01992 - - 0.0000000000000000000000000000000000000002196 166.0
TLS3_k127_8186719_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 405.0
TLS3_k127_8186719_1 Response regulator receiver K11443 - - 0.000000000000000000000000000001382 126.0
TLS3_k127_8186719_2 DNA helicase - - - 0.0000000000000003489 82.0
TLS3_k127_8188686_0 ATPase associated with various cellular K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 443.0
TLS3_k127_8188686_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000003542 181.0
TLS3_k127_8188686_2 Belongs to the glycosyl hydrolase 13 family - - - 0.0000000000000000000000000000000000005166 158.0
TLS3_k127_8191242_0 Site-specific DNA-methyltransferase (Adenine-specific) K06223 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 370.0
TLS3_k127_8191242_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000143 282.0
TLS3_k127_8191242_2 PFAM metallophosphoesterase - - - 0.000000000000000000000000000000000000000003913 164.0
TLS3_k127_8191242_4 Tellurite resistance protein TehB - - - 0.0000000000000000000000001084 115.0
TLS3_k127_8195767_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 361.0
TLS3_k127_8195767_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 295.0
TLS3_k127_8195767_2 lipoprotein biosynthetic process K13292 - - 0.0000000000000000001938 95.0
TLS3_k127_8200790_0 Predicted permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 351.0
TLS3_k127_8200790_1 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 306.0
TLS3_k127_8200790_2 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001002 242.0
TLS3_k127_8200790_3 Belongs to the SEDS family - - - 0.000000000000000000000000000000000000000000000000000008163 207.0
TLS3_k127_8200790_4 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000009031 178.0
TLS3_k127_8200790_5 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000467 154.0
TLS3_k127_8200790_6 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000004441 128.0
TLS3_k127_8200790_7 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000007933 119.0
TLS3_k127_8200790_8 Bacterial regulatory proteins, tetR family K03577 - - 0.00000000000000000000000000009631 123.0
TLS3_k127_8204195_0 protein histidine kinase activity K02484,K07636,K07642 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 444.0
TLS3_k127_8204195_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008996 285.0
TLS3_k127_8204195_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000413 156.0
TLS3_k127_8204195_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000002737 105.0
TLS3_k127_8204195_4 - - - - 0.000000000000000004582 85.0
TLS3_k127_8226030_0 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954 303.0
TLS3_k127_8226030_1 Methyltransferase type 11 - - - 0.000000000000000000000000000002548 128.0
TLS3_k127_8226030_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000004405 116.0
TLS3_k127_8227337_0 - - - - 0.0000000000001183 81.0
TLS3_k127_8227337_1 CAAX protease self-immunity K07052 - - 0.0005965 51.0
TLS3_k127_8237407_0 pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 483.0
TLS3_k127_8237407_1 glycine betaine transport K02002 - - 0.000000000000000000000000000000000000000000003984 174.0
TLS3_k127_8243902_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001292 266.0
TLS3_k127_8243902_2 PFAM AzlC family protein - - - 0.000000000000000000000000000000000000000000000000000000000009479 215.0
TLS3_k127_8243902_3 AAA domain - - - 0.000000000000000000000000000000000000000000000000005542 187.0
TLS3_k127_8243902_4 Putative stress-induced transcription regulator - - - 0.0000000000000000000000000000000000000000000006556 174.0
TLS3_k127_8243902_5 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.000000000000000000000000000000000000000000008642 162.0
TLS3_k127_8243902_6 membrane - - - 0.0000000000000000001446 92.0
TLS3_k127_8243902_7 Protein of unknown function (DUF805) - - - 0.000000000000000001775 92.0
TLS3_k127_8243902_8 Helix-turn-helix XRE-family like proteins - - - 0.000000001873 65.0
TLS3_k127_8260490_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 380.0
TLS3_k127_8260490_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000008912 232.0
TLS3_k127_8260490_2 Male sterility protein K00091 - 1.1.1.219 0.0000004489 54.0
TLS3_k127_8263026_0 CoA-ligase K02381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006207 576.0
TLS3_k127_8263026_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000001309 72.0
TLS3_k127_8263026_2 belongs to the nudix hydrolase family K03574 - 3.6.1.55 0.00000000001688 68.0
TLS3_k127_8272388_0 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007568 506.0
TLS3_k127_8272388_1 PFAM formylmethanofuran dehydrogenase, subunit E region K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000001303 220.0
TLS3_k127_8272388_2 TIGRFAM amino acid adenylation domain - - - 0.000000000000000000000004096 109.0
TLS3_k127_8280750_0 - - - - 0.0000000000002296 84.0
TLS3_k127_8280750_1 beta-galactosidase activity - - - 0.00003816 53.0
TLS3_k127_8293966_0 Heavy metal translocating P-type atpase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 411.0
TLS3_k127_8293966_1 ribonuclease II K01147 - 3.1.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 372.0
TLS3_k127_8293966_2 Methyl-viologen-reducing hydrogenase, delta subunit K02572,K02573,K03522 - - 0.000000000000000000000000000000000000000000000000000000000000003269 244.0
TLS3_k127_8293966_3 Transcriptional regulator, Crp Fnr family K21564 - - 0.0000000000000000000000000000000000000000000000001008 186.0
TLS3_k127_8293966_4 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000001716 109.0
TLS3_k127_8293966_5 PFAM Ribonuclease II K01147 - 3.1.13.1 0.0000000000000007214 83.0
TLS3_k127_8293966_6 - - - - 0.000000214 55.0
TLS3_k127_8300940_0 phosphorelay signal transduction system K07670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001966 277.0
TLS3_k127_8300940_1 AMP binding K03294 - - 0.000000000000000000000000000000000001239 151.0
TLS3_k127_8300940_2 PhoQ Sensor - - - 0.00000000000000000002752 92.0
TLS3_k127_8306380_0 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 479.0
TLS3_k127_8316974_0 PFAM basic membrane lipoprotein K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 450.0
TLS3_k127_8316974_2 Bacterial toxin of type II toxin-antitoxin system, YafQ K19157 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006415,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032984,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034655,GO:0042221,GO:0042710,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043565,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044010,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044764,GO:0044877,GO:0046483,GO:0046677,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 - 0.00000000000000000000000000007462 117.0
TLS3_k127_8324026_0 FAD linked oxidase domain protein - - - 0.0 1095.0
TLS3_k127_8326476_0 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 355.0
TLS3_k127_8326476_1 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000000000000000000000009967 221.0
TLS3_k127_8326882_0 COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 377.0
TLS3_k127_8326882_1 glycosyl transferase group 1 K08256 - 2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000001799 231.0
TLS3_k127_8326882_2 TIGRFAM competence damage-inducible protein CinA K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000000000000009259 163.0
TLS3_k127_8326882_3 Belongs to the UPF0102 family K07460 - - 0.00000007699 56.0
TLS3_k127_8326882_4 Crp-like helix-turn-helix domain - - - 0.0003026 49.0
TLS3_k127_8328055_0 P-loop Domain of unknown function (DUF2791) K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000004063 212.0
TLS3_k127_8328055_1 DEAD H associated K03724 - - 0.000000000000000000000000009617 115.0
TLS3_k127_8328055_3 P-loop Domain of unknown function (DUF2791) - - - 0.00000138 61.0
TLS3_k127_8329747_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000001491 257.0
TLS3_k127_8329747_1 SMART PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000002568 233.0
TLS3_k127_8345695_0 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 550.0
TLS3_k127_8345695_1 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000000000000000000000001866 229.0
TLS3_k127_8345695_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000318 218.0
TLS3_k127_8345695_3 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000116 206.0
TLS3_k127_8354988_0 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 505.0
TLS3_k127_8354988_1 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 366.0
TLS3_k127_8354988_2 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001366 277.0
TLS3_k127_8354988_3 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000006817 182.0
TLS3_k127_8354988_4 Protein of unknown function (DUF1361) - - - 0.0000000000000000000000000000000001132 141.0
TLS3_k127_8354988_5 COGs COG0491 Zn-dependent hydrolase including glyoxylase - - - 0.000000000000000000000001013 108.0
TLS3_k127_8354988_7 transmembrane sensor domain - - - 0.00000001134 64.0
TLS3_k127_8354988_8 - - - - 0.000004201 57.0
TLS3_k127_8355779_0 Penicillin-Binding Protein C-terminus Family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 455.0
TLS3_k127_8355779_1 Thioesterase domain K01071 - 3.1.2.21 0.000000000000000000000000000000000000000000000000000000000000000004451 231.0
TLS3_k127_839150_0 Two component transcriptional regulator, winged helix family K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007442 262.0
TLS3_k127_839150_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000152 235.0
TLS3_k127_839150_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000004201 192.0
TLS3_k127_839150_3 response regulator K07657 - - 0.00000003286 61.0
TLS3_k127_8407324_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 375.0
TLS3_k127_8407324_1 tRNA rRNA methyltransferase K00556,K03218,K03437 - 2.1.1.185,2.1.1.34 0.000000001488 67.0
TLS3_k127_8408726_0 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007205 352.0
TLS3_k127_8408726_1 PFAM ABC transporter related K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 331.0
TLS3_k127_8408726_2 ABC transporter, ATP-binding protein K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 308.0
TLS3_k127_8408726_3 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000001317 204.0
TLS3_k127_8408726_4 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000002245 189.0
TLS3_k127_8414391_0 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 559.0
TLS3_k127_8414391_1 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 441.0
TLS3_k127_8414391_2 Pyridoxal-phosphate dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 344.0
TLS3_k127_8414391_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000003048 217.0
TLS3_k127_8414391_4 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000008575 185.0
TLS3_k127_8414391_5 Response regulator, receiver K02030,K03407,K07679,K11443,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.00000000000000000000000000000005677 129.0
TLS3_k127_8414391_6 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.000000000000000000363 90.0
TLS3_k127_8418918_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 6.935e-213 692.0
TLS3_k127_8418918_1 Hsp70 protein K04046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 392.0
TLS3_k127_8418918_2 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000006717 192.0
TLS3_k127_8418918_3 COG3119 Arylsulfatase A and related enzymes - - - 0.0000015 51.0
TLS3_k127_8432694_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 312.0
TLS3_k127_8432694_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000001366 205.0
TLS3_k127_8432694_2 Domain of unknown function (DUF4870) - - - 0.00000000000000000000000009198 109.0
TLS3_k127_8432694_3 Protein of unknown function (DUF4013) - - - 0.00000000000000000000004574 108.0
TLS3_k127_8432694_4 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.000000000000000002806 87.0
TLS3_k127_8432694_5 Polymer-forming cytoskeletal - - - 0.000000000000006176 86.0
TLS3_k127_8442741_0 Platelet-activating factor acetylhydrolase, isoform II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 361.0
TLS3_k127_8442741_1 Methyltransferase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001211 280.0
TLS3_k127_8442741_2 polysaccharide catabolic process K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000002307 259.0
TLS3_k127_8442741_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003417 249.0
TLS3_k127_8442741_4 - - - - 0.0000000000000000000000000000000000000000002061 168.0
TLS3_k127_8442741_5 - - - - 0.00003322 54.0
TLS3_k127_8443142_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 548.0
TLS3_k127_8443142_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 332.0
TLS3_k127_8443142_2 Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000001575 176.0
TLS3_k127_8443142_3 Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000001182 167.0
TLS3_k127_8461193_0 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 514.0
TLS3_k127_8461193_1 Protein of unknown function (DUF3105) - - - 0.0000000000000000000000000000000000000000000000479 177.0
TLS3_k127_8461193_2 Protein of unknown function (DUF3105) - - - 0.000000000000000000000000000000000000000000001846 170.0
TLS3_k127_8462705_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 359.0
TLS3_k127_8462705_1 PFAM peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 297.0
TLS3_k127_8462705_2 Domain of unknown function (DUF427) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001137 256.0
TLS3_k127_8462705_3 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000004482 250.0
TLS3_k127_8464016_0 peptidase M24 K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 330.0
TLS3_k127_8464016_1 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 310.0
TLS3_k127_8464016_2 precorrin-2 dehydrogenase activity K02302,K02304 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000002259 250.0
TLS3_k127_8464016_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000002598 255.0
TLS3_k127_8464016_4 Domain of unknown function (DUF892) - - - 0.00000000000000000000000000000000000000000001535 167.0
TLS3_k127_8464016_5 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 0.000000000003222 76.0
TLS3_k127_8464900_0 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 439.0
TLS3_k127_8464900_1 COGs COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006711 404.0
TLS3_k127_8464900_2 Pyruvate ferredoxin oxidoreductase and related K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000001926 173.0
TLS3_k127_846985_0 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000002383 191.0
TLS3_k127_846985_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000002082 144.0
TLS3_k127_846985_2 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.0000000000000000000000000000008289 123.0
TLS3_k127_846985_3 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000009515 133.0
TLS3_k127_8470947_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 345.0
TLS3_k127_8470947_1 Redoxin - - - 0.000000000000000000000000000000000000004214 148.0
TLS3_k127_8470947_2 Tocopherol cyclase - - - 0.0000000000001477 76.0
TLS3_k127_8470947_3 Redoxin K03564 - 1.11.1.15 0.000002986 50.0
TLS3_k127_8480552_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 610.0
TLS3_k127_8480552_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 329.0
TLS3_k127_8480552_2 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.19.3 0.000000000000000000000000000000000000000000000000000000000000001306 224.0
TLS3_k127_8480552_3 cellulose binding - - - 0.000000000000000000000000000000000001511 151.0
TLS3_k127_8480552_4 cell redox homeostasis K02199 - - 0.0000000000000000000000000001447 119.0
TLS3_k127_8480552_5 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.000000000000000000000000002732 124.0
TLS3_k127_8480552_6 Copper resistance protein K07156 - - 0.0000000000003384 76.0
TLS3_k127_8481526_0 helix_turn_helix, Lux Regulon K03556 - - 7.255e-312 981.0
TLS3_k127_8481526_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 442.0
TLS3_k127_8481526_2 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 397.0
TLS3_k127_8481526_3 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 355.0
TLS3_k127_8481526_5 - - - - 0.0000000184 60.0
TLS3_k127_8488118_0 Belongs to the malate synthase family K01638 - 2.3.3.9 3.345e-227 713.0
TLS3_k127_8488118_1 sequence-specific DNA binding K07110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 535.0
TLS3_k127_8488118_2 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 523.0
TLS3_k127_8488118_3 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005612 271.0
TLS3_k127_8499922_0 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000001158 160.0
TLS3_k127_8499922_1 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000001038 132.0
TLS3_k127_8499922_2 AntiSigma factor - - - 0.0000000000000000000000005909 116.0
TLS3_k127_8499922_3 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000001115 89.0
TLS3_k127_8502359_0 Cobalamin B12-binding K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000007187 181.0
TLS3_k127_8502359_1 GTPase activity K07588 - - 0.00000000000000000000000000000000000000003262 155.0
TLS3_k127_8502359_2 domain, Protein K01185,K01224,K01447,K01876,K11904,K21472 - 3.2.1.17,3.2.1.89,3.5.1.28,6.1.1.12 0.000000000000000000000000000000001441 149.0
TLS3_k127_8502359_3 - - - - 0.000001255 55.0
TLS3_k127_8509391_0 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 445.0
TLS3_k127_8509391_1 PFAM VWA containing CoxE family protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 425.0
TLS3_k127_8509391_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000004131 108.0
TLS3_k127_8509391_3 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000001697 60.0
TLS3_k127_8533556_0 PFAM ABC transporter K05833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 294.0
TLS3_k127_8533556_1 transport system permease K05832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004532 265.0
TLS3_k127_8533556_2 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000004544 261.0
TLS3_k127_8533556_3 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000002644 165.0
TLS3_k127_8533556_4 N-terminal half of MaoC dehydratase - - - 0.0001668 44.0
TLS3_k127_8536333_0 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 407.0
TLS3_k127_8536333_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002132 265.0
TLS3_k127_8546787_0 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 382.0
TLS3_k127_8546787_1 glycosyl transferase family 28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007645 366.0
TLS3_k127_8546787_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 342.0
TLS3_k127_8546787_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002614 275.0
TLS3_k127_8546787_4 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000003664 240.0
TLS3_k127_8546787_5 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000001836 168.0
TLS3_k127_8546787_6 ABC-type transport system involved in multi-copper enzyme maturation, permease K01992 - - 0.000000000000000000000000000000000008237 146.0
TLS3_k127_8546787_8 - - - - 0.0000000000001741 78.0
TLS3_k127_8546787_9 - - - - 0.00003002 48.0
TLS3_k127_8549501_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 1.464e-270 878.0
TLS3_k127_8549501_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 360.0
TLS3_k127_8549501_2 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000001402 208.0
TLS3_k127_8554187_0 Baseplate J-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009463 522.0
TLS3_k127_8554187_1 Glycosyltransferase family 28 N-terminal domain K05841 - 2.4.1.173 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 351.0
TLS3_k127_8554187_2 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001055 263.0
TLS3_k127_8554187_3 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000938 138.0
TLS3_k127_8554187_4 Phage tail protein (Tail_P2_I) - - - 0.0000000000000000000000000000002297 129.0
TLS3_k127_8554187_5 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000000000000000000001336 100.0
TLS3_k127_8562426_0 Subtilase family K17734 - - 0.0000000000000000000000000000000000000000000000000000000000000000006204 259.0
TLS3_k127_8562426_1 cellulase activity K01201 - 3.2.1.45 0.0008242 53.0
TLS3_k127_8565243_0 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 398.0
TLS3_k127_8566242_0 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 437.0
TLS3_k127_8566242_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000002626 79.0
TLS3_k127_8574382_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0 1009.0
TLS3_k127_8574382_1 COGs COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008062 606.0
TLS3_k127_8574382_2 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 543.0
TLS3_k127_8574382_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 541.0
TLS3_k127_8574382_4 trisaccharide binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 403.0
TLS3_k127_8574382_5 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000001244 178.0
TLS3_k127_8574382_6 Cytochrome c - - - 0.0000000000000000000000000000000009139 133.0
TLS3_k127_8574382_7 Haem-binding domain - - - 0.0000000000000000000000000113 114.0
TLS3_k127_8576252_0 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 1.757e-281 881.0
TLS3_k127_8576252_1 Histidine kinase - - - 0.000000000002452 69.0
TLS3_k127_8578505_0 cellulose binding - - - 4.056e-221 689.0
TLS3_k127_8578505_1 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001204 228.0
TLS3_k127_8578505_10 Protein of unknown function (DUF1706) - - - 0.00000000000000000000000000000000003859 139.0
TLS3_k127_8578505_11 helix_turn_helix, arabinose operon control protein K21701 - - 0.00000000000000000000000000000000004244 137.0
TLS3_k127_8578505_12 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000002025 136.0
TLS3_k127_8578505_13 Domain of unknown function (DU1801) - - - 0.000000000000000000000002097 107.0
TLS3_k127_8578505_15 Glycosyl transferase, family 2 - - - 0.0000000000003259 71.0
TLS3_k127_8578505_16 Domain of unknown function (DUF1905) - - - 0.0000003779 53.0
TLS3_k127_8578505_2 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000000000000000000000000000004317 212.0
TLS3_k127_8578505_3 - - - - 0.000000000000000000000000000000000000000000000000000000001588 203.0
TLS3_k127_8578505_4 Pfam RibD C-terminal domain K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000003257 202.0
TLS3_k127_8578505_5 DinB family - - - 0.0000000000000000000000000000000000000000000000000000005778 198.0
TLS3_k127_8578505_6 - - - - 0.0000000000000000000000000000000000000000000000008165 177.0
TLS3_k127_8578505_7 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000004143 162.0
TLS3_k127_8578505_8 enzyme binding K05982,K07452 - 3.1.21.7 0.000000000000000000000000000000000000000002385 158.0
TLS3_k127_8578505_9 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000000000000000000000000000000000000005026 147.0
TLS3_k127_8578852_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 485.0
TLS3_k127_8578852_1 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000007641 102.0
TLS3_k127_8578852_2 - - - - 0.0000000145 61.0
TLS3_k127_8578852_3 Horizontally Transferred TransMembrane Domain - - - 0.0000001315 56.0
TLS3_k127_858136_0 PFAM ABC transporter transmembrane region K06147 - - 7.174e-216 685.0
TLS3_k127_858136_1 PFAM Prenyltransferase squalene oxidase - - - 0.000000000000000000000000107 113.0
TLS3_k127_8586849_0 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000001557 251.0
TLS3_k127_8586849_1 HIT domain - - - 0.0000000000000000000000000000001311 129.0
TLS3_k127_8586849_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000002618 132.0
TLS3_k127_8586849_3 Helix-hairpin-helix motif K02237 - - 0.00000002442 66.0
TLS3_k127_8591168_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001603 238.0
TLS3_k127_8591168_1 COG0433 Predicted ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000021 224.0
TLS3_k127_8591168_2 lysozyme - - - 0.0000000000000000000000000000000000000000000000000000000004508 205.0
TLS3_k127_8591168_3 - - - - 0.000000000000000000000001056 108.0
TLS3_k127_8591168_5 - - - - 0.0000000000000009286 83.0
TLS3_k127_8591168_6 - - - - 0.00000000001368 75.0
TLS3_k127_8591168_7 - - - - 0.000000000871 66.0
TLS3_k127_8591168_9 lysozyme - - - 0.00000002066 61.0
TLS3_k127_869368_0 Condensation domain - - - 4.865e-284 913.0
TLS3_k127_873271_0 Binding-protein-dependent transport system inner membrane component K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000003083 236.0
TLS3_k127_873271_1 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000001452 228.0
TLS3_k127_873271_2 Bacterial extracellular solute-binding protein K11069 - - 0.0000000000000000000000000000000000000000000000000005531 198.0
TLS3_k127_873271_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000001144 102.0
TLS3_k127_873271_4 Transcriptional regulator padr family - - - 0.000000000000000001239 89.0
TLS3_k127_873271_5 PFAM Forkhead-associated protein - - - 0.00000000000000004151 90.0
TLS3_k127_886125_0 Glutamate synthase K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1611.0
TLS3_k127_895663_0 protein histidine kinase activity K01768,K11527,K18143 - 2.7.13.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000002648 259.0
TLS3_k127_895663_1 protein histidine kinase activity K01768,K11527,K18143 - 2.7.13.3,4.6.1.1 0.0000000000000000000000000000000001365 149.0
TLS3_k127_901906_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008919 241.0
TLS3_k127_901906_1 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000001509 228.0
TLS3_k127_901906_2 - - - - 0.0000000000000000000000000000000000000509 147.0
TLS3_k127_901906_3 PFAM sodium calcium exchanger membrane region K07301 - - 0.000000000000002961 77.0
TLS3_k127_901906_4 Uncharacterised protein family (UPF0175) - - - 0.0000000000001158 74.0
TLS3_k127_901906_5 - - - - 0.0000000004356 64.0
TLS3_k127_905006_0 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002516 282.0
TLS3_k127_905006_1 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006677 257.0
TLS3_k127_905006_2 His Kinase A (phosphoacceptor) domain - - - 0.00001139 58.0
TLS3_k127_927010_0 SMART Elongator protein 3 MiaB NifB - - - 1.332e-266 831.0
TLS3_k127_927010_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 334.0
TLS3_k127_941418_0 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 339.0
TLS3_k127_941418_1 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000008984 235.0
TLS3_k127_941418_2 Calx-beta domain - - - 0.00000000000000000000000000000000000000000000000000006106 213.0
TLS3_k127_941418_3 PFAM Maf family protein K06287 - - 0.00000000000000000000000000000000000002665 152.0
TLS3_k127_941418_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000003444 97.0
TLS3_k127_941418_5 Type IV pilus biogenesis stability protein PilW - - - 0.000005944 57.0
TLS3_k127_948701_0 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 369.0
TLS3_k127_948701_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 349.0
TLS3_k127_948701_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003093 253.0
TLS3_k127_948701_3 acetyltransferase K15520 - 2.3.1.189 0.00000000000000000000000000000000000000000000000000001107 196.0
TLS3_k127_948701_4 Male sterility protein - - - 0.000000000000000000000000000001013 135.0
TLS3_k127_948701_5 Aldo/keto reductase family - - - 0.0000000007082 61.0
TLS3_k127_948701_6 TPR repeat - - - 0.00006318 53.0
TLS3_k127_948835_0 PFAM PfkB domain protein K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 411.0
TLS3_k127_948835_1 ATPase activity K02010,K02052,K02062,K11072 - 3.6.3.30,3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 309.0
TLS3_k127_948835_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002404 262.0
TLS3_k127_948835_3 COGs COG0463 Glycosyltransferase involved in cell wall biogenesis K20534 - - 0.00000000000000000000000000000000000000000000000000000129 203.0
TLS3_k127_957920_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 9.14e-322 992.0
TLS3_k127_957920_1 Mo-molybdopterin cofactor metabolic process K03636 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 373.0
TLS3_k127_957920_2 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000000003372 135.0
TLS3_k127_957920_3 TIGRFAM MoaD family protein K03636 - - 0.00000000000000000000000000000001306 129.0
TLS3_k127_982137_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0 1322.0
TLS3_k127_991890_0 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 334.0
TLS3_k127_991890_1 Stage II sporulation protein M - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 340.0
TLS3_k127_991890_2 YCII-related domain - - - 0.00000000255 61.0