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Overview

ID MAG04051
Name TLS3_bin.3
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Actinomycetota
Class Nitriliruptoria
Order Euzebyales
Family JAHELV01
Genus
Species
Assembly information
Completeness (%) 76.05
Contamination (%) 3.87
GC content (%) 74.0
N50 (bp) 7,592
Genome size (bp) 4,761,289

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4319

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1000572_0 Maltogenic Amylase, C-terminal domain K05343 GO:0000023,GO:0000271,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016160,GO:0016161,GO:0016787,GO:0016798,GO:0016853,GO:0016866,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046872,GO:0047471,GO:0055114,GO:0071704,GO:0071944,GO:1901576 3.2.1.1,5.4.99.16 2.64e-276 859.0
TLS3_k127_1000572_1 Protein of unknown function (DUF3417) K00688 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.4.1.1 8.172e-251 801.0
TLS3_k127_1000572_2 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 1.134e-211 677.0
TLS3_k127_1000572_3 Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity) K16146 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016310,GO:0034637,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046835,GO:0071704,GO:0071944,GO:1901576 2.7.1.175 0.000000000000000000000000000000001254 145.0
TLS3_k127_1001500_0 FAD binding domain K14672,K15972 - 1.14.13.200 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 389.0
TLS3_k127_1001500_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 364.0
TLS3_k127_1001500_2 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 334.0
TLS3_k127_1001500_3 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009098 316.0
TLS3_k127_1001500_4 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000169 275.0
TLS3_k127_1001500_5 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003144 265.0
TLS3_k127_1001500_6 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000003691 174.0
TLS3_k127_1001500_7 acetyltransferase K03829 - - 0.0000000000000000000000000000000000000000008787 160.0
TLS3_k127_1001500_8 Cupin domain - - - 0.0000000000000000000000000000000000000001102 162.0
TLS3_k127_1007456_0 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0003674,GO:0003824,GO:0004422,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0052657,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000009163 243.0
TLS3_k127_1007456_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075 GO:0008150,GO:0040007 2.4.2.8,6.3.4.19 0.0000000000000000000000000000000000000000005908 174.0
TLS3_k127_1009565_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000001011 197.0
TLS3_k127_1013032_0 carbamoyl transferase, NodU family K00612 - - 1.308e-218 688.0
TLS3_k127_1014049_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 434.0
TLS3_k127_1014049_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 358.0
TLS3_k127_1014049_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 319.0
TLS3_k127_1023295_0 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002968 235.0
TLS3_k127_1023295_1 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000001756 218.0
TLS3_k127_1023295_2 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000005242 214.0
TLS3_k127_1023295_3 tRNA threonylcarbamoyladenosine modification K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000005247 183.0
TLS3_k127_1023295_4 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000002608 169.0
TLS3_k127_1023295_5 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.0000000000000000000000000001701 126.0
TLS3_k127_1023295_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06925 GO:0008150,GO:0040007 - 0.0000000000000000000001603 114.0
TLS3_k127_1023295_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000005139 57.0
TLS3_k127_1045268_0 Domain of unknown function (DUF4389) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 407.0
TLS3_k127_1065408_0 Na+/Pi-cotransporter K03324,K14683 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 308.0
TLS3_k127_1065408_1 TrkA-C domain K07228 - - 0.0000000000000000000000000000000000008725 150.0
TLS3_k127_1065408_2 Sodium hydrogen exchanger K03455 - - 0.00000000000000000000000000000000836 130.0
TLS3_k127_1069011_0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain K05989 - 3.2.1.40 0.0 1267.0
TLS3_k127_1069011_1 hydrolase, family 3 K05349 - 3.2.1.21 7.373e-311 975.0
TLS3_k127_1069011_10 conserved protein containing a ferredoxin-like domain K18929 - - 0.000000000000000000000000000000002413 143.0
TLS3_k127_1069011_2 ATPases associated with a variety of cellular activities K10562 - 3.6.3.17 2.716e-216 689.0
TLS3_k127_1069011_3 Bacterial extracellular solute-binding protein K10117 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 548.0
TLS3_k127_1069011_4 Periplasmic binding protein domain K02058,K10559 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 468.0
TLS3_k127_1069011_5 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 435.0
TLS3_k127_1069011_6 Binding-protein-dependent transport system inner membrane component K02025,K10118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 436.0
TLS3_k127_1069011_7 Binding-protein-dependent transport system inner membrane component K10119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 405.0
TLS3_k127_1069011_8 Ribose xylose arabinose galactoside ABC-type transport systems, permease components K10560 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 394.0
TLS3_k127_1069011_9 Branched-chain amino acid transport system / permease component K10561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 381.0
TLS3_k127_1078805_0 O-acetylhomoserine K01740 - 2.5.1.49 8.381e-212 666.0
TLS3_k127_1078805_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 441.0
TLS3_k127_1078805_2 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00651 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0008899,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 428.0
TLS3_k127_1078805_3 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 351.0
TLS3_k127_1078805_4 Acetyl xylan esterase (AXE1) K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 311.0
TLS3_k127_1078805_5 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000001308 247.0
TLS3_k127_1078805_6 AraC-binding-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004494 231.0
TLS3_k127_1078805_7 peptidase C60 sortase A and B - - - 0.0000000000000000000000000000000000000000000004316 169.0
TLS3_k127_1078805_8 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000000001647 123.0
TLS3_k127_1081303_0 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000002235 248.0
TLS3_k127_1081303_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000005151 220.0
TLS3_k127_1081303_2 PFAM Methicillin resistance protein - - - 0.000000000000000000000000000002 130.0
TLS3_k127_1087988_0 potassium ion transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 363.0
TLS3_k127_1087988_1 Integral membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003805 274.0
TLS3_k127_1087988_2 Dodecin K09165 - - 0.000000000000000004067 91.0
TLS3_k127_1098288_0 Glycosyl hydrolases family 39 K01198 - 3.2.1.37 8.166e-229 748.0
TLS3_k127_1098288_1 Protein of unknown function (DUF3131) - - - 1.919e-204 653.0
TLS3_k127_1098288_10 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 375.0
TLS3_k127_1098288_11 COG0346 Lactoylglutathione lyase and related lyases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 347.0
TLS3_k127_1098288_12 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 320.0
TLS3_k127_1098288_13 Glycosyl hydrolases family 15 K22308 - 3.2.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 293.0
TLS3_k127_1098288_14 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000001539 226.0
TLS3_k127_1098288_15 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000000000000000000000000000000000862 226.0
TLS3_k127_1098288_16 Domain of unknown function (DUF1905) - - - 0.0000000000000000000000000001609 129.0
TLS3_k127_1098288_17 - - - - 0.000000000000000000004848 99.0
TLS3_k127_1098288_19 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000207 63.0
TLS3_k127_1098288_2 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 604.0
TLS3_k127_1098288_3 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 498.0
TLS3_k127_1098288_4 Binding-protein-dependent transport system inner membrane component K10119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 433.0
TLS3_k127_1098288_5 PFAM binding-protein-dependent transport systems inner membrane component K10118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 407.0
TLS3_k127_1098288_6 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 402.0
TLS3_k127_1098288_7 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 386.0
TLS3_k127_1098288_8 Bacterial extracellular solute-binding protein K10117 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 409.0
TLS3_k127_1098288_9 Binding-protein-dependent transport system inner membrane component K02026,K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 374.0
TLS3_k127_1104997_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003526 254.0
TLS3_k127_1104997_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000003723 202.0
TLS3_k127_1106951_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 5.751e-207 666.0
TLS3_k127_1106951_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 362.0
TLS3_k127_1106951_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 338.0
TLS3_k127_1106951_3 Electron transfer flavoprotein alpha subunit K03522 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 308.0
TLS3_k127_1106951_4 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000411 272.0
TLS3_k127_1106951_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000005797 161.0
TLS3_k127_1106951_6 PFAM AIG2 family protein - - - 0.00000000000000000000000000000000000002716 154.0
TLS3_k127_1106951_7 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000001936 132.0
TLS3_k127_1106951_8 - - - - 0.000000000000000000000009214 105.0
TLS3_k127_1106951_9 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 0.00000000000000000000008092 101.0
TLS3_k127_1115239_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00271 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.4.1.23 0.000000000000000000000000000000000000000641 151.0
TLS3_k127_1116880_0 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 464.0
TLS3_k127_1116880_1 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 379.0
TLS3_k127_1116880_2 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 336.0
TLS3_k127_1116880_3 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995,K11957 GO:0003333,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015808,GO:0015818,GO:0015829,GO:0015849,GO:0015893,GO:0032328,GO:0034220,GO:0042221,GO:0042493,GO:0042940,GO:0042941,GO:0043090,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903805,GO:1903806,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 296.0
TLS3_k127_1116880_4 branched-chain amino acid K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 293.0
TLS3_k127_1116880_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000003251 170.0
TLS3_k127_1116880_6 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.000000000000000000003481 104.0
TLS3_k127_1144350_0 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 443.0
TLS3_k127_1144350_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003556 276.0
TLS3_k127_1144350_2 Transcriptional regulatory protein, C terminal K07776 - - 0.000000000000000000000000000001627 126.0
TLS3_k127_1144350_3 Armadillo/beta-catenin-like repeats - - - 0.000000000000000000000000006232 124.0
TLS3_k127_1146161_0 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 492.0
TLS3_k127_1146161_1 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000006829 233.0
TLS3_k127_1146161_2 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000001067 199.0
TLS3_k127_1146161_3 Phosphate transporter family - - - 0.00000000000000000000000000000000000000000000000005944 189.0
TLS3_k127_1146161_4 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000006434 140.0
TLS3_k127_1146161_6 Transcriptional activator domain - - - 0.00000003969 56.0
TLS3_k127_1150904_0 Glycosyl hydrolases family 6 K19668 - 3.2.1.91 8.141e-236 736.0
TLS3_k127_1150904_1 Belongs to the DEAD box helicase family K05592,K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 3.665e-212 674.0
TLS3_k127_1150904_2 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 438.0
TLS3_k127_1150904_3 Major Facilitator Superfamily - - - 0.00002427 56.0
TLS3_k127_1154300_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 450.0
TLS3_k127_1154300_1 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.00000000000000000000000000000000000000000000000000000007811 203.0
TLS3_k127_117522_0 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 417.0
TLS3_k127_117522_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 377.0
TLS3_k127_117522_2 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004565 275.0
TLS3_k127_117522_3 ABC transporter, ATP-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005625 250.0
TLS3_k127_1187286_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000001071 195.0
TLS3_k127_1187286_1 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000001363 156.0
TLS3_k127_1187286_2 Rhodanese-related sulfurtransferase - - - 0.00000000000000000000000008257 110.0
TLS3_k127_1187286_3 phosphohistidine phosphatase K08296 - - 0.000000002683 65.0
TLS3_k127_1193737_0 amino acid K20265 - - 2.65e-260 809.0
TLS3_k127_1193737_1 Peptidase dimerisation domain - - - 7.086e-226 706.0
TLS3_k127_1193737_2 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 425.0
TLS3_k127_1193737_3 membrane protein of uknown function UCP014873 - - - 0.00000000000000000000000000000000000000000000000002358 185.0
TLS3_k127_1193737_4 Belongs to the peptidase M24B family K01271,K01274 - 3.4.13.9 0.0000000000000000000000000000000000000000000000007243 196.0
TLS3_k127_1193737_5 - - - - 0.00000000000000000000000000000000002077 142.0
TLS3_k127_1193737_6 Short C-terminal domain - - - 0.000000000000000000000000000005831 122.0
TLS3_k127_1195314_0 - - - - 0.00000000000004063 86.0
TLS3_k127_1195314_1 - - - - 0.0000000001963 70.0
TLS3_k127_1198650_0 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009468 277.0
TLS3_k127_1198650_1 PFAM short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000004154 238.0
TLS3_k127_1198650_2 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.000000000000000000000000000000000000000000000000000000000001137 215.0
TLS3_k127_1198650_3 Methyltransferase domain - - - 0.00000000000000000000000000000001639 133.0
TLS3_k127_1198650_4 Transcriptional regulator - - - 0.000000000000000000000000301 120.0
TLS3_k127_1198650_5 pyridoxamine 5-phosphate - - - 0.000023 51.0
TLS3_k127_1198650_6 Short repeat of unknown function (DUF308) - - - 0.0002485 53.0
TLS3_k127_1204187_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 338.0
TLS3_k127_1204187_1 ABC-2 family transporter protein K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000003159 239.0
TLS3_k127_1204187_2 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000001004 207.0
TLS3_k127_1204187_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000006747 196.0
TLS3_k127_1204187_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000009816 192.0
TLS3_k127_1204187_5 glutamine amidotransferase - - - 0.000000000000000000000000004503 126.0
TLS3_k127_1237091_0 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006193 285.0
TLS3_k127_1237091_1 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000005289 192.0
TLS3_k127_1251662_0 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 393.0
TLS3_k127_1251662_1 Glycolate oxidase subunit GlcD K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 380.0
TLS3_k127_1255736_0 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 539.0
TLS3_k127_1255736_1 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000007187 157.0
TLS3_k127_1266390_0 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008656 577.0
TLS3_k127_1266390_1 Platelet-activating factor acetylhydrolase, isoform II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 452.0
TLS3_k127_1266390_10 YGGT family - - - 0.0000000000000002199 88.0
TLS3_k127_1266390_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 388.0
TLS3_k127_1266390_3 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 379.0
TLS3_k127_1266390_4 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003408 273.0
TLS3_k127_1266390_5 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004261 256.0
TLS3_k127_1266390_6 MafB19-like deaminase K01487 - 3.5.4.3 0.000000000000000000000000000000000000000001103 168.0
TLS3_k127_1266390_7 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000001679 157.0
TLS3_k127_1266390_8 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000001275 143.0
TLS3_k127_1266390_9 DNA helicase - - - 0.0000000000000000000000000000001396 134.0
TLS3_k127_1266993_0 Male sterility protein K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 516.0
TLS3_k127_1266993_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007316 444.0
TLS3_k127_1266993_2 Belongs to the DegT DnrJ EryC1 family K12452 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 400.0
TLS3_k127_1266993_3 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377,K16554 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 372.0
TLS3_k127_1266993_4 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 364.0
TLS3_k127_1266993_5 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 368.0
TLS3_k127_1266993_6 Dehydrogenase E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 350.0
TLS3_k127_1266993_7 HAD-hyrolase-like K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000006382 216.0
TLS3_k127_1266993_8 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000468 197.0
TLS3_k127_1279305_0 xanthine dehydrogenase, a b hammerhead - - - 1.093e-279 882.0
TLS3_k127_1279305_1 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 332.0
TLS3_k127_1279305_2 Xanthine dehydrogenase iron-sulfur cluster and FAD-binding subunit A K13481 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000219 260.0
TLS3_k127_1279305_3 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004986 261.0
TLS3_k127_1279305_4 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000001452 204.0
TLS3_k127_1279305_5 dienelactone hydrolase - - - 0.00000000000000000000000000000000000004609 154.0
TLS3_k127_1279305_6 Putative sensor - - - 0.0000000007199 64.0
TLS3_k127_1285330_0 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007572 272.0
TLS3_k127_1285330_1 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000001808 228.0
TLS3_k127_1294147_0 Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 589.0
TLS3_k127_1294147_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 500.0
TLS3_k127_1294147_2 amino acid ABC transporter, ATP-binding protein K02028,K17076 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 364.0
TLS3_k127_1294147_3 FAD linked oxidase K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 317.0
TLS3_k127_1294147_4 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 291.0
TLS3_k127_1294147_5 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000008424 231.0
TLS3_k127_1294147_6 C-terminal, D2-small domain, of ClpB protein K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 0.0000000000000000000000000000000000000000000001267 181.0
TLS3_k127_1294147_7 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K02030 - - 0.00000000000000000000000000000053 124.0
TLS3_k127_1294147_8 OsmC-like protein - - - 0.00000000002147 73.0
TLS3_k127_1301677_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 339.0
TLS3_k127_1301677_1 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 296.0
TLS3_k127_1301677_2 - - - - 0.00000000000000047 85.0
TLS3_k127_1305815_0 Belongs to the aldehyde dehydrogenase family - - - 5.786e-213 672.0
TLS3_k127_1305815_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 310.0
TLS3_k127_1305815_2 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005989 293.0
TLS3_k127_1305815_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001539 260.0
TLS3_k127_1305815_4 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002322 254.0
TLS3_k127_1305815_5 NADPH quinone - - - 0.000000000000000000000000000000000000000000000000000000000000000003731 239.0
TLS3_k127_1305815_6 COGs COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000009869 211.0
TLS3_k127_1305815_7 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000001831 179.0
TLS3_k127_1305815_8 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00001529 57.0
TLS3_k127_1305815_9 Pfam:DUF59 - - - 0.00002288 53.0
TLS3_k127_1315190_0 Cell envelope-related transcriptional attenuator domain - - - 0.00000000000000000000000000000000000000000000000009246 196.0
TLS3_k127_1315190_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000001101 181.0
TLS3_k127_1315190_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA - - - 0.00000000000000000001059 95.0
TLS3_k127_1345468_0 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 605.0
TLS3_k127_1345468_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 560.0
TLS3_k127_1345468_2 Pectate lyase K01728 - 4.2.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 539.0
TLS3_k127_1345468_3 Protein of unknown function (DUF993) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 470.0
TLS3_k127_1345468_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 429.0
TLS3_k127_1345468_5 Xylose isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 402.0
TLS3_k127_1345468_6 Belongs to the DapA family K01707,K01714 - 4.2.1.41,4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 383.0
TLS3_k127_1345468_7 GDP-mannose 4,6 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 352.0
TLS3_k127_1357709_0 Bacterial protein of unknown function (DUF839) K07093 - - 1.531e-220 704.0
TLS3_k127_1357709_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 394.0
TLS3_k127_1357709_2 protein conserved in bacteria containing thioredoxin-like domain - - - 0.00000000000000000000000000000000000000000000000002106 190.0
TLS3_k127_1357709_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000007571 183.0
TLS3_k127_1362836_0 transcriptional regulator - - - 0.000000000000000000000000000000006903 134.0
TLS3_k127_1362836_1 - - - - 0.0004341 52.0
TLS3_k127_1375997_0 MobA-like NTP transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 318.0
TLS3_k127_1375997_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000004725 102.0
TLS3_k127_140861_0 ABC-type sugar transport system, ATPase component K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 501.0
TLS3_k127_140861_1 deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000000002147 245.0
TLS3_k127_140861_2 Glycoside hydrolase, family 20 - - - 0.000001622 61.0
TLS3_k127_1420801_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002847 278.0
TLS3_k127_1420801_1 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000001217 154.0
TLS3_k127_1420801_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000003655 113.0
TLS3_k127_1420801_3 Histidine kinase - - - 0.00000000000003027 75.0
TLS3_k127_1420801_4 acyl-CoA dehydrogenase - - - 0.00000000168 59.0
TLS3_k127_1420801_5 Histidine kinase - - - 0.000000666 58.0
TLS3_k127_1420801_6 ATPases associated with a variety of cellular activities K01990 - - 0.000004853 51.0
TLS3_k127_1420801_7 helix_turn_helix, Lux Regulon - - - 0.0003512 47.0
TLS3_k127_144318_0 Bacterial protein of unknown function (DUF899) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009972 366.0
TLS3_k127_144318_1 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000103 291.0
TLS3_k127_144318_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 293.0
TLS3_k127_144318_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000004863 145.0
TLS3_k127_1450065_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K15408 - 1.9.3.1 0.0 1247.0
TLS3_k127_1450065_1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.0000000000000000000000000000000000000000001337 171.0
TLS3_k127_1455089_0 Domain of unknown function (DUF427) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 329.0
TLS3_k127_1455089_1 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 304.0
TLS3_k127_1455089_2 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001366 249.0
TLS3_k127_1455089_3 decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006756 242.0
TLS3_k127_1455089_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000005027 114.0
TLS3_k127_1455089_5 Rho termination factor, N-terminal domain - - - 0.00000000000000000000000002416 109.0
TLS3_k127_1455089_6 Bacterial regulatory proteins, tetR family - - - 0.0003014 47.0
TLS3_k127_146099_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 597.0
TLS3_k127_146099_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 567.0
TLS3_k127_146099_2 Acetyltransferase (GNAT) domain K02348 - - 0.000000000000000000000000000000000000000000009935 170.0
TLS3_k127_146099_3 Septum formation initiator family protein K09009 - - 0.000000000000000000000000000000000000000007916 166.0
TLS3_k127_146099_4 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein - - - 0.000000000000000000000000000000000006238 147.0
TLS3_k127_146099_5 Septum formation initiator K13052 - - 0.0000000001512 68.0
TLS3_k127_1469361_0 Bacterial transcriptional activator domain - - - 4.176e-194 638.0
TLS3_k127_1469361_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00140,K00823 - 1.2.1.18,1.2.1.27,2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 537.0
TLS3_k127_1469361_10 cobalamin (vitamin B12) biosynthesis CbiX K03795 - 4.99.1.3 0.00000000000000000000000000000000000000000000000000000000007122 219.0
TLS3_k127_1469361_11 TIGRFAM TIGR00725 family protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000000001014 159.0
TLS3_k127_1469361_12 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000001625 94.0
TLS3_k127_1469361_13 Amino acid-binding act domain protein - - - 0.00000003059 62.0
TLS3_k127_1469361_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008295 524.0
TLS3_k127_1469361_3 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008979 452.0
TLS3_k127_1469361_4 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 367.0
TLS3_k127_1469361_5 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 357.0
TLS3_k127_1469361_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007542 327.0
TLS3_k127_1469361_7 acetyltransferase - GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 303.0
TLS3_k127_1469361_8 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001711 277.0
TLS3_k127_1469361_9 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000616 240.0
TLS3_k127_1473713_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 3.242e-228 719.0
TLS3_k127_1475094_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001971 255.0
TLS3_k127_1475094_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07671 GO:0000287,GO:0003674,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043167,GO:0043169,GO:0044110,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051704,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000005315 233.0
TLS3_k127_1505414_0 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 365.0
TLS3_k127_1505677_0 Actin K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 441.0
TLS3_k127_1505677_1 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 392.0
TLS3_k127_1505677_2 RadC-like JAB domain K03630 - - 0.0000000000000000000000003113 118.0
TLS3_k127_1505677_3 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000001388 106.0
TLS3_k127_1505677_4 - - - - 0.000004206 58.0
TLS3_k127_1505677_5 Tfp pilus assembly protein FimV - - - 0.00001634 57.0
TLS3_k127_1522628_0 Heparinase II/III N-terminus - - - 0.00000000000000005916 95.0
TLS3_k127_1531269_0 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain K13633 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 381.0
TLS3_k127_1531269_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000006936 248.0
TLS3_k127_1531269_2 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000379 188.0
TLS3_k127_1531269_3 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000000000000000000002447 126.0
TLS3_k127_1531269_4 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0002762 46.0
TLS3_k127_1534510_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 3.404e-208 668.0
TLS3_k127_1534510_1 Belongs to the BCCT transporter (TC 2.A.15) family K02168 - - 1.149e-206 668.0
TLS3_k127_1534510_10 flagellar hook-associated protein K02396 - - 0.000000000000000000000000000000000000000000000000003175 203.0
TLS3_k127_1534510_11 GGDEF domain - - - 0.00000000000000000000000000000000000000000000006502 192.0
TLS3_k127_1534510_12 Bacterial flagellin N-terminal helical region K02397 - - 0.0000000000000000000000000000000000000005176 160.0
TLS3_k127_1534510_13 Peptidase, M23 K21471 - - 0.000000000000000000000000000000000000001543 156.0
TLS3_k127_1534510_14 3-methyladenine DNA glycosylase - - - 0.00000000000000000000000000001769 130.0
TLS3_k127_1534510_15 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.00000000000000000006107 98.0
TLS3_k127_1534510_16 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.000000000000000075 84.0
TLS3_k127_1534510_17 FIST C domain - - - 0.000000002027 61.0
TLS3_k127_1534510_18 DnaJ C terminal domain - - - 0.00000005591 64.0
TLS3_k127_1534510_19 FlgN protein - - - 0.0000004091 61.0
TLS3_k127_1534510_2 Nad-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 524.0
TLS3_k127_1534510_3 Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 384.0
TLS3_k127_1534510_4 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 357.0
TLS3_k127_1534510_5 succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000001802 264.0
TLS3_k127_1534510_6 5'-3' exonuclease - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000326 245.0
TLS3_k127_1534510_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000001575 234.0
TLS3_k127_1534510_8 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000006166 211.0
TLS3_k127_1534510_9 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000002776 205.0
TLS3_k127_1542156_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000001218 263.0
TLS3_k127_1542156_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001151 261.0
TLS3_k127_1542156_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000005365 252.0
TLS3_k127_1542156_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000001802 63.0
TLS3_k127_1565126_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003856 240.0
TLS3_k127_1565126_1 Divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000002154 128.0
TLS3_k127_1565126_2 Bacterial-like globin K06886 GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0019825,GO:0020012,GO:0020037,GO:0030682,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0042737,GO:0043207,GO:0044237,GO:0044248,GO:0044270,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046209,GO:0046210,GO:0046906,GO:0048037,GO:0050896,GO:0051213,GO:0051410,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:0075136,GO:0097159,GO:0098754,GO:1901363,GO:1901698,GO:2001057 - 0.000000000000004612 87.0
TLS3_k127_1567144_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 473.0
TLS3_k127_1567144_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 428.0
TLS3_k127_1567144_2 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 307.0
TLS3_k127_1567144_3 PASTA K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000114 235.0
TLS3_k127_1584576_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 8.772e-281 920.0
TLS3_k127_1584576_1 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 580.0
TLS3_k127_1584576_2 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 377.0
TLS3_k127_1584576_3 Periplasmic binding protein domain K10543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 350.0
TLS3_k127_1584576_4 ATPases associated with a variety of cellular activities K10545 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 336.0
TLS3_k127_1584576_5 FGGY family of carbohydrate kinases, C-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001814 273.0
TLS3_k127_1585939_0 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 544.0
TLS3_k127_1592929_0 alcohol dehydrogenase K00004,K00008 - 1.1.1.14,1.1.1.303,1.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 424.0
TLS3_k127_1592929_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000002598 157.0
TLS3_k127_1601582_0 - - - - 0.00000000000000000000000000000000000000000000000001039 198.0
TLS3_k127_1601582_1 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000344 181.0
TLS3_k127_1601582_3 PFAM Pentapeptide repeats (8 copies) - - - 0.00000000000000004464 94.0
TLS3_k127_1604577_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 1.475e-312 967.0
TLS3_k127_1604577_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 480.0
TLS3_k127_1604577_10 Exonuclease K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000003953 208.0
TLS3_k127_1604577_11 - - - - 0.000000000000000000000000000000000000000000000000001999 192.0
TLS3_k127_1604577_12 membrane protein domain - - - 0.000000009953 65.0
TLS3_k127_1604577_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 403.0
TLS3_k127_1604577_3 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 410.0
TLS3_k127_1604577_4 succinate dehydrogenase K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 367.0
TLS3_k127_1604577_5 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 355.0
TLS3_k127_1604577_6 Transcriptional regulators of sugar metabolism - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 287.0
TLS3_k127_1604577_7 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002165 287.0
TLS3_k127_1604577_8 beta-galactosidase K12308 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004386 272.0
TLS3_k127_1604577_9 succinate dehydrogenase K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004055 250.0
TLS3_k127_1605242_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 346.0
TLS3_k127_1605242_1 Oxidoreductase FAD-binding domain K00529,K02613 GO:0000166,GO:0003674,GO:0005488,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0036094,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0097159,GO:0098754,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 1.18.1.3 0.00000000000000000000000000000000000000000000000003151 188.0
TLS3_k127_1605242_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000004094 184.0
TLS3_k127_1605242_3 Nitroreductase family - - - 0.00000000000000000000000000000000000000000003927 169.0
TLS3_k127_1605242_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000132 72.0
TLS3_k127_1618173_0 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 516.0
TLS3_k127_1618173_1 Enoyl-CoA hydratase isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000000000000005724 213.0
TLS3_k127_1618173_2 - - - - 0.000000000000000000000000000000000000117 149.0
TLS3_k127_1619931_0 Tex-like protein N-terminal domain K06959 - - 0.0 1149.0
TLS3_k127_1619931_1 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 302.0
TLS3_k127_1628205_0 CobQ/CobB/MinD/ParA nucleotide binding domain K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 407.0
TLS3_k127_1628205_1 ABC-type Mn2 Zn2 transport systems permease components K02075,K09819 - - 0.000000000000000000000000000000000000000000000000000000000000000000002716 247.0
TLS3_k127_1628205_2 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000001345 244.0
TLS3_k127_1628205_3 ABC transporter K11603 - - 0.0000000000000000000000000000000000000000000000000000000000001024 233.0
TLS3_k127_1628205_4 - - - - 0.00000000000000000000000000000000000000000000000000005541 190.0
TLS3_k127_163848_0 Mg-chelatase subunit ChlI K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 521.0
TLS3_k127_163848_1 von Willebrand factor type A - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 464.0
TLS3_k127_163848_2 Rhodanese Homology Domain K01011 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 349.0
TLS3_k127_163848_3 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 361.0
TLS3_k127_163848_4 endonuclease exonuclease phosphatase - - - 0.00000000000000000000001372 113.0
TLS3_k127_163848_5 Anti-sigma regulatory factor (Ser Thr protein kinase) K04757 - 2.7.11.1 0.000000000000088 84.0
TLS3_k127_163848_6 gas vesicle protein - - - 0.0009931 50.0
TLS3_k127_1674416_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 434.0
TLS3_k127_1674416_1 AraC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000478 274.0
TLS3_k127_1674416_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000004032 268.0
TLS3_k127_1674416_3 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000007106 191.0
TLS3_k127_1690860_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008981 448.0
TLS3_k127_1690860_1 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 359.0
TLS3_k127_1690860_2 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 338.0
TLS3_k127_1690860_3 WD40 repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000001463 248.0
TLS3_k127_1690860_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000002165 223.0
TLS3_k127_1690860_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000001573 159.0
TLS3_k127_1690860_6 Transcriptional regulator - - - 0.000000000000000000000000000000000000000238 156.0
TLS3_k127_1690860_7 Ethanolamine utilisation protein EutQ K04030 - - 0.000000000000000000000000000001827 137.0
TLS3_k127_1706942_0 Type II/IV secretion system protein K02283 - - 0.0000000000000000000000000000000001081 153.0
TLS3_k127_1706942_1 NUBPL iron-transfer P-loop NTPase - - - 0.000000006369 66.0
TLS3_k127_1722576_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.1.11.5 1.989e-257 842.0
TLS3_k127_1722576_1 Viral (Superfamily 1) RNA helicase K03581 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 499.0
TLS3_k127_1722576_2 regulation of methylation-dependent chromatin silencing K07454 - - 0.000000000000000000000000000000000000009116 147.0
TLS3_k127_1722576_3 Exodeoxyribonuclease V, gamma subunit - - - 0.00000000000000000000000000001759 126.0
TLS3_k127_1722576_4 Phage derived protein Gp49-like (DUF891) - - - 0.000000000000000000000008235 107.0
TLS3_k127_1722576_5 Helix-turn-helix XRE-family like proteins - - - 0.000000000005078 72.0
TLS3_k127_1733148_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1642.0
TLS3_k127_1733148_1 Belongs to the glycosyl hydrolase family 6 - - - 4.629e-195 620.0
TLS3_k127_1733148_2 Glycosyl hydrolase family 12 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 400.0
TLS3_k127_1733148_3 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001021 298.0
TLS3_k127_1733148_4 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000000000000000000000000000000000000000001826 251.0
TLS3_k127_1733148_5 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006986 246.0
TLS3_k127_1736857_0 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 383.0
TLS3_k127_1736857_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007386 277.0
TLS3_k127_1736857_2 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000001116 213.0
TLS3_k127_1739148_0 diguanylate cyclase - - - 7.283e-285 908.0
TLS3_k127_1739148_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000003147 239.0
TLS3_k127_1739148_10 ABC transporter K06147 - - 0.000000000000000000000002441 112.0
TLS3_k127_1739148_11 AraC-like ligand binding domain - - - 0.000000000000000004308 95.0
TLS3_k127_1739148_12 - - - - 0.00000002241 62.0
TLS3_k127_1739148_2 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000002088 219.0
TLS3_k127_1739148_3 MafB19-like deaminase K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 0.000000000000000000000000000000000000000000000000003949 188.0
TLS3_k127_1739148_4 zinc metalloprotease K06402 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.00000000000000000000000000000000000000001002 168.0
TLS3_k127_1739148_5 Belongs to the peptidase S16 family K07177 - - 0.0000000000000000000000000000000000000000376 167.0
TLS3_k127_1739148_6 - - - - 0.0000000000000000000000000000000000000006477 166.0
TLS3_k127_1739148_7 PFAM globin K06886 - - 0.000000000000000000000000000000003426 134.0
TLS3_k127_1739148_8 AAA ATPase domain - - - 0.000000000000000000000000000002394 130.0
TLS3_k127_1739148_9 - - - - 0.00000000000000000000000000001498 121.0
TLS3_k127_1749516_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 2.505e-216 694.0
TLS3_k127_1749516_1 membrane protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 385.0
TLS3_k127_1749516_2 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 359.0
TLS3_k127_1749516_3 transmembrane transport - - - 0.00000000000000000000000000000000000000000000000001211 196.0
TLS3_k127_1749516_4 Cell wall-associated - - - 0.000000000269 71.0
TLS3_k127_1754460_0 Phosphate acyltransferases - - - 0.00000000000000000000000000000003338 143.0
TLS3_k127_175841_0 Peptidase M1 membrane alanine aminopeptidase - - - 9.412e-273 857.0
TLS3_k127_175841_1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 605.0
TLS3_k127_175841_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 292.0
TLS3_k127_175841_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002146 233.0
TLS3_k127_175841_4 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000001028 187.0
TLS3_k127_1766242_0 Mannose-1-phosphate guanylyltransferase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000002757 213.0
TLS3_k127_1766242_1 Polysaccharide biosynthesis protein - - - 0.0000003493 61.0
TLS3_k127_1766242_2 CDP-alcohol phosphatidyltransferase - - - 0.000000415 63.0
TLS3_k127_1768061_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 436.0
TLS3_k127_1768061_1 Sulfotransferase domain K01014 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006790,GO:0008146,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016782,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0046505,GO:0046506,GO:0071704,GO:1901576 2.8.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 383.0
TLS3_k127_1768061_2 PFAM Glycosyl hydrolase family 32 K01193 - 3.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000095 317.0
TLS3_k127_1768061_3 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000002941 250.0
TLS3_k127_1768061_4 PAC2 family - - - 0.000000000000000000000000000000000000000000000000000000000000003666 230.0
TLS3_k127_1768061_5 Yqey-like protein K09117 - - 0.00000000000000000000000000000009795 132.0
TLS3_k127_1768061_6 Phage integrase family - - - 0.000000000000000000000000000271 123.0
TLS3_k127_1768061_7 GtrA-like protein - - - 0.00000000000001001 87.0
TLS3_k127_1768061_8 Serine aminopeptidase, S33 - - - 0.0000000000005813 80.0
TLS3_k127_1777709_0 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000002097 207.0
TLS3_k127_1777709_1 peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.00000000000000000000000000000000000000000000000000007165 204.0
TLS3_k127_1777709_2 Domain of Unknown Function (DUF1206) - - - 0.00000000000000000002527 91.0
TLS3_k127_1777709_3 Transposase - - - 0.00000000000000002063 93.0
TLS3_k127_1797994_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006967 299.0
TLS3_k127_1797994_1 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000001252 224.0
TLS3_k127_1800910_0 Non-essential cell division protein that could be required for efficient cell constriction - - - 7.085e-231 753.0
TLS3_k127_1800910_1 Peptidase M16 - - - 6.507e-206 649.0
TLS3_k127_1800910_10 RNA polymerase II transcriptional preinitiation complex assembly - - - 0.00000000005309 71.0
TLS3_k127_1800910_2 Glycosyl hydrolases family 6 K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 590.0
TLS3_k127_1800910_3 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 576.0
TLS3_k127_1800910_4 Peptidase M16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 574.0
TLS3_k127_1800910_5 VWA domain containing CoxE-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 519.0
TLS3_k127_1800910_6 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 458.0
TLS3_k127_1800910_7 Low temperature requirement A - - - 0.0000000000000000000000000000000000000000000004786 181.0
TLS3_k127_1800910_8 transcriptional regulator - - - 0.00000000000000000000000000000003491 132.0
TLS3_k127_1800910_9 response to heat K06867,K07090 - - 0.00000000000000000115 100.0
TLS3_k127_1817216_0 choline-sulfatase K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 598.0
TLS3_k127_1817216_1 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 397.0
TLS3_k127_1817216_2 beta-fructofuranosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 382.0
TLS3_k127_1817216_3 response to hydroperoxide K09861 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 341.0
TLS3_k127_1817216_4 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 286.0
TLS3_k127_1817216_5 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000008634 241.0
TLS3_k127_1817216_6 Transmembrane protease, serine 9 K01316,K09614,K09640 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0010467,GO:0016485,GO:0016787,GO:0017171,GO:0019538,GO:0031638,GO:0031639,GO:0043170,GO:0044238,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.9 0.000000008631 57.0
TLS3_k127_1818310_0 Thiamine pyrophosphate enzyme, central domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009059 608.0
TLS3_k127_1828083_0 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000002128 235.0
TLS3_k127_1828083_1 UTRA K03710 - - 0.00000000000000000000000000000000000000000000000000000000001642 215.0
TLS3_k127_1828083_2 - - - - 0.000000000000000006693 93.0
TLS3_k127_1848859_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 612.0
TLS3_k127_1848859_1 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000006124 79.0
TLS3_k127_1854597_0 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 381.0
TLS3_k127_1854597_1 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000001268 194.0
TLS3_k127_1854597_2 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000005356 184.0
TLS3_k127_1854597_3 Protein of unknown function (DUF3040) - - - 0.0000002655 59.0
TLS3_k127_1854597_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0001219 48.0
TLS3_k127_1873327_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009407 538.0
TLS3_k127_1875895_0 Recombinase K06400 - - 5.617e-199 638.0
TLS3_k127_1875895_1 Transposase - - - 0.00000000000000003383 81.0
TLS3_k127_1883966_0 PFAM Uncharacterised protein family UPF0182 K09118 - - 1.15e-213 693.0
TLS3_k127_1883966_1 AsnC-type helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 349.0
TLS3_k127_1883966_2 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 324.0
TLS3_k127_1883966_3 hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000886 239.0
TLS3_k127_1883966_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000005131 196.0
TLS3_k127_1883966_5 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000004123 169.0
TLS3_k127_1883966_6 NAD dependent epimerase/dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000376 169.0
TLS3_k127_1883966_7 Molybdopterin converting factor, large subunit K03635 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 0.0000000000000000000000000000001248 132.0
TLS3_k127_1883966_8 Phage portal protein - - - 0.0006934 52.0
TLS3_k127_1906335_0 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 513.0
TLS3_k127_1906335_1 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 312.0
TLS3_k127_1906335_2 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 308.0
TLS3_k127_1911156_0 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000000000000000000000000000000000000000000000003252 241.0
TLS3_k127_1911156_1 Histidine kinase - - - 0.000000000000000000000000000000000000000008132 177.0
TLS3_k127_1911156_2 Stage II sporulation E family protein - - - 0.00000000000315 70.0
TLS3_k127_1911270_0 PFAM Glycoside hydrolase, family 38 - - - 0.0 1075.0
TLS3_k127_1911270_1 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000002951 194.0
TLS3_k127_1911270_2 peptidyl-prolyl cis-trans isomerase activity K00645,K02597,K03769,K03771 - 2.3.1.39,5.2.1.8 0.0000000000000000000000000000000000000004891 169.0
TLS3_k127_1911270_3 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000005101 76.0
TLS3_k127_1924958_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006148 263.0
TLS3_k127_1924958_1 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000003915 269.0
TLS3_k127_1924958_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000181 253.0
TLS3_k127_1944373_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 3.271e-265 837.0
TLS3_k127_1944373_1 SurA N-terminal domain - - - 0.00000000001936 72.0
TLS3_k127_1944373_2 Evidence 4 Homologs of previously reported genes of - - - 0.00000005841 56.0
TLS3_k127_1963660_0 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 341.0
TLS3_k127_1963660_1 ABC transporter (Periplasmic binding protein) K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 319.0
TLS3_k127_1963660_2 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009941 315.0
TLS3_k127_1963660_3 Methyltransferase K10218 - 4.1.3.17 0.0000000000000000000000000000000000003171 153.0
TLS3_k127_1963660_4 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000001568 149.0
TLS3_k127_1967013_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 313.0
TLS3_k127_1967013_1 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000006199 238.0
TLS3_k127_1967013_2 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000002005 194.0
TLS3_k127_1967013_3 Glutaredoxin K00384 - 1.8.1.9 0.00000000002257 67.0
TLS3_k127_1968300_0 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 523.0
TLS3_k127_1968300_1 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 441.0
TLS3_k127_1968300_10 deazaflavin-dependent nitroreductase family protein - - - 0.00001221 48.0
TLS3_k127_1968300_2 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 442.0
TLS3_k127_1968300_3 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 400.0
TLS3_k127_1968300_4 Esterase PHB depolymerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004586 328.0
TLS3_k127_1968300_5 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000002509 198.0
TLS3_k127_1968300_6 positive regulation of growth K07746 - - 0.000000000000000000000000000000000000000000000000006566 183.0
TLS3_k127_1968300_7 conserved protein, contains double-stranded beta-helix domain - - - 0.000000000000000000002044 98.0
TLS3_k127_1968300_8 - - - - 0.000000000000000001057 101.0
TLS3_k127_1968300_9 Domain of unknown function (DUF309) K09763 - - 0.000007225 49.0
TLS3_k127_1968861_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 529.0
TLS3_k127_1971886_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 552.0
TLS3_k127_1971886_1 amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 408.0
TLS3_k127_1971886_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 397.0
TLS3_k127_1971886_3 Belongs to the binding-protein-dependent transport system permease family K01997,K11956 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 398.0
TLS3_k127_1971886_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 376.0
TLS3_k127_1971886_5 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 358.0
TLS3_k127_1971886_6 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 337.0
TLS3_k127_1971886_7 Response regulator receiver K22010 GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000107 255.0
TLS3_k127_1971886_8 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000005111 233.0
TLS3_k127_1971886_9 Belongs to the TrpC family K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.0000000000000000000000000000003408 128.0
TLS3_k127_1972523_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 4.879e-215 674.0
TLS3_k127_1972523_1 Animal haem peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 482.0
TLS3_k127_1972523_2 Periplasmic binding protein LacI transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 330.0
TLS3_k127_1972523_3 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008447 282.0
TLS3_k127_1972523_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000803 275.0
TLS3_k127_1972523_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000005262 265.0
TLS3_k127_1972523_6 diguanylate cyclase - - - 0.0000000000000000000000000006308 129.0
TLS3_k127_1992195_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 397.0
TLS3_k127_1992195_1 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000007168 189.0
TLS3_k127_1992195_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000639 145.0
TLS3_k127_1992195_3 PFAM Transcription regulator, TetR-like, DNA-binding, bacterial archaeal - - - 0.000000000001614 77.0
TLS3_k127_1992195_4 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000008977 53.0
TLS3_k127_1997767_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 368.0
TLS3_k127_1997767_1 Glycosyl Hydrolase Family 88 - - - 0.0000000000000000000000000000000000000000000000000002056 191.0
TLS3_k127_2004963_0 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 409.0
TLS3_k127_2004963_1 Transport permease protein K09694 - - 0.00000000000000000000000000000000000000000000000000000003348 217.0
TLS3_k127_2004963_2 haloacid dehalogenase-like hydrolase K07026 - 3.1.3.70 0.0000000000000000000000000000000000000000000000000005194 193.0
TLS3_k127_201310_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 524.0
TLS3_k127_2020597_0 ATP synthase alpha/beta chain, C terminal domain K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008638 612.0
TLS3_k127_2020597_1 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 410.0
TLS3_k127_2020597_2 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000006886 205.0
TLS3_k127_2020597_3 F1 subunit gamma K02115 - - 0.000000000000000000000000000000000000000000000000000004996 202.0
TLS3_k127_2020597_4 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000001348 186.0
TLS3_k127_2021207_0 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006474 268.0
TLS3_k127_2021207_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000009391 244.0
TLS3_k127_2021207_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 6.3.2.9 0.00000000000000000000000000000000000006505 149.0
TLS3_k127_2027535_0 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 503.0
TLS3_k127_2027535_1 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 482.0
TLS3_k127_2027535_10 Oxidoreductase - - - 0.00000000000000000000000000001964 125.0
TLS3_k127_2027535_2 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 410.0
TLS3_k127_2027535_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 372.0
TLS3_k127_2027535_4 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 347.0
TLS3_k127_2027535_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 317.0
TLS3_k127_2027535_6 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000267 277.0
TLS3_k127_2027535_7 positive regulation of transcription, DNA-templated K09684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005471 252.0
TLS3_k127_2027535_8 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000706 227.0
TLS3_k127_2027535_9 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000001139 204.0
TLS3_k127_2031336_0 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 4.019e-221 694.0
TLS3_k127_2031336_1 Amino acid permease K16238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 468.0
TLS3_k127_2031336_2 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 336.0
TLS3_k127_2031336_3 Transcriptional regulator K05799 - - 0.00000000000000000000000000000000000000000000000000000000000695 224.0
TLS3_k127_2031336_4 glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000007132 215.0
TLS3_k127_2031336_5 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.000000000004838 70.0
TLS3_k127_2031336_6 - - - - 0.0002773 52.0
TLS3_k127_2034563_0 Aconitate hydratase 1 K01681 - 4.2.1.3 0.0 1282.0
TLS3_k127_2034563_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657 3.3.1.1 2.661e-265 824.0
TLS3_k127_2034563_2 FAD binding domain K19189 - 1.14.13.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 369.0
TLS3_k127_2034563_3 PFAM Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001892 281.0
TLS3_k127_2034563_4 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.000000000000000000000000000000000000000000000000000008775 196.0
TLS3_k127_2034563_5 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000005771 156.0
TLS3_k127_2034563_6 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000009353 111.0
TLS3_k127_2034563_7 CBS domain K04767 - - 0.000000000000000000002507 98.0
TLS3_k127_2035391_0 Belongs to the FGGY kinase family K00851 - 2.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 441.0
TLS3_k127_2035391_1 Bacterial extracellular solute-binding protein K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 390.0
TLS3_k127_2035391_2 gntR family - - - 0.0000000000000000000000000000000000000000000000000000000254 220.0
TLS3_k127_2035391_3 metal-sulfur cluster biosynthetic enzyme - - - 0.0000000000000000000000001093 115.0
TLS3_k127_2035391_4 pyridoxamine 5-phosphate - - - 0.0000000000000000000000001229 112.0
TLS3_k127_2054983_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 374.0
TLS3_k127_2054983_1 peptidase dimerisation domain protein K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000044 275.0
TLS3_k127_2054983_2 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000002948 191.0
TLS3_k127_2054983_3 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000003081 170.0
TLS3_k127_2054983_4 5'-3' exonuclease, C-terminal SAM fold K02335 - 2.7.7.7 0.00000000000000000000000000000000000001136 160.0
TLS3_k127_2054983_5 amino acid transport - - - 0.000000000003798 77.0
TLS3_k127_205841_0 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 528.0
TLS3_k127_205841_1 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 475.0
TLS3_k127_205841_2 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00000000000000000000000001412 113.0
TLS3_k127_2077562_0 Domain of unknown function (DUF3516) - - - 3.986e-277 878.0
TLS3_k127_2077562_1 Uncharacterised ACR (DUF711) K09157 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 566.0
TLS3_k127_2077562_2 belongs to the sigma-70 factor family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 544.0
TLS3_k127_2077562_3 short chain dehydrogenase K00218 - 1.3.1.33 0.000000000000000000000000000000000000000000000000000000000000000001082 241.0
TLS3_k127_2077562_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000007733 199.0
TLS3_k127_2077562_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000001526 96.0
TLS3_k127_2077562_6 ACT domain K03567 - - 0.0000000000124 73.0
TLS3_k127_2077562_7 Protein of unknown function (DUF664) - - - 0.000000000955 61.0
TLS3_k127_2083408_0 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009 373.0
TLS3_k127_2083408_1 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 375.0
TLS3_k127_2083408_2 Histone acetyltransferase - - - 0.0002984 50.0
TLS3_k127_2089576_0 penicillin-binding protein K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 415.0
TLS3_k127_2089576_1 trisaccharide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 327.0
TLS3_k127_2089576_2 Methyltransferase domain - - - 0.000000000000000000007423 96.0
TLS3_k127_2091039_0 Oxidoreductase K10219 - 1.1.1.312 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 471.0
TLS3_k127_2091039_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000002076 197.0
TLS3_k127_2094193_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.56e-231 730.0
TLS3_k127_2094193_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01190,K05350 - 3.2.1.21,3.2.1.23 2.085e-223 709.0
TLS3_k127_2094193_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 422.0
TLS3_k127_2094193_11 transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 404.0
TLS3_k127_2094193_12 transport K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 406.0
TLS3_k127_2094193_13 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 377.0
TLS3_k127_2094193_14 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 383.0
TLS3_k127_2094193_15 endo-1,4-beta-xylanase activity K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 361.0
TLS3_k127_2094193_16 PFAM Glycosyl hydrolase family 32 K01193 - 3.2.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 333.0
TLS3_k127_2094193_17 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 305.0
TLS3_k127_2094193_18 PFAM Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 290.0
TLS3_k127_2094193_19 periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001827 291.0
TLS3_k127_2094193_2 cellulose binding - - - 2.862e-196 617.0
TLS3_k127_2094193_20 Dna alkylation repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003615 271.0
TLS3_k127_2094193_21 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005366 259.0
TLS3_k127_2094193_22 ATPases associated with a variety of cellular activities K01995,K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000001156 243.0
TLS3_k127_2094193_23 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000002539 249.0
TLS3_k127_2094193_24 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000003274 251.0
TLS3_k127_2094193_25 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000017 223.0
TLS3_k127_2094193_26 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000008676 218.0
TLS3_k127_2094193_27 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000005849 218.0
TLS3_k127_2094193_28 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000008986 194.0
TLS3_k127_2094193_29 COG4177 ABC-type branched-chain amino acid transport system, permease component - - - 0.0000000000000000000000000000000000000000000000000003022 207.0
TLS3_k127_2094193_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 533.0
TLS3_k127_2094193_30 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000000256 189.0
TLS3_k127_2094193_31 COG0559 Branched-chain amino acid ABC-type transport system, permease components - - - 0.0000000000000000000000000000000000000000000000005386 194.0
TLS3_k127_2094193_32 Beta-lactamase K01286 - 3.4.16.4 0.00000000000000000000000000000000000001136 160.0
TLS3_k127_2094193_33 Pfam Zn-finger in ubiquitin-hydrolases and other protein - - - 0.00000000000000000000000000000002757 132.0
TLS3_k127_2094193_34 Protein of unknown function (DUF3887) - - - 0.000000000000000000000002568 114.0
TLS3_k127_2094193_35 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.0000000000000000000003848 107.0
TLS3_k127_2094193_36 - - - - 0.000000000000000000001043 102.0
TLS3_k127_2094193_37 Protein of unknown function (DUF3224) - - - 0.000000000000000000006158 98.0
TLS3_k127_2094193_38 - - - - 0.0000000000002584 82.0
TLS3_k127_2094193_4 Aldehyde dehydrogenase family K14519 - 1.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 511.0
TLS3_k127_2094193_5 4-hydroxybenzoate K00481 - 1.14.13.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 514.0
TLS3_k127_2094193_6 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 491.0
TLS3_k127_2094193_7 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008407 461.0
TLS3_k127_2094193_8 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 463.0
TLS3_k127_2094193_9 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 450.0
TLS3_k127_2105282_0 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000003578 179.0
TLS3_k127_2105282_1 Antibiotic biosynthesis monooxygenase K21481 - 1.14.99.57 0.000000000000000000000000001581 123.0
TLS3_k127_2116949_0 malto-oligosyltrehalose synthase K06044 - 5.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 299.0
TLS3_k127_2116949_1 CAAX protease self-immunity K07052 - - 0.0000000000000003562 80.0
TLS3_k127_2117165_0 Phosphomethylpyrimidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005813 252.0
TLS3_k127_2117165_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000003983 142.0
TLS3_k127_2117165_2 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000001403 89.0
TLS3_k127_2123657_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005727 269.0
TLS3_k127_2123657_1 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000003165 173.0
TLS3_k127_2123657_2 Sigma-70, region 4 K03088 - - 0.000000000000000000000000271 111.0
TLS3_k127_2128304_0 Bacterial transcriptional activator domain - - - 1.168e-240 786.0
TLS3_k127_2128304_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004387 282.0
TLS3_k127_2135800_0 Epoxide hydrolase N terminus K21159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 542.0
TLS3_k127_2135800_1 WYL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 447.0
TLS3_k127_2135800_2 Domain of unknown function (DUF1996) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 300.0
TLS3_k127_2135800_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006918 268.0
TLS3_k127_2135800_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000009741 207.0
TLS3_k127_2135800_5 auxin-activated signaling pathway K07088 - - 0.000000000000000000000000000000000000000000000000000001078 203.0
TLS3_k127_2135800_6 Excalibur calcium-binding domain - - - 0.00000000491 64.0
TLS3_k127_2148401_0 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process K07067 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 407.0
TLS3_k127_2148401_1 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 374.0
TLS3_k127_2148401_2 Transcriptional regulator, CarD family K07736 GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.000000000000000000000000000000000000000000000000000008649 195.0
TLS3_k127_2148401_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000133 173.0
TLS3_k127_2148401_4 serine threonine protein kinase - - - 0.000000000000001202 91.0
TLS3_k127_2162042_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 7.642e-260 832.0
TLS3_k127_2162042_1 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 527.0
TLS3_k127_2162042_2 Glycosyl hydrolase family 12 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 304.0
TLS3_k127_2162042_3 Capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003053 287.0
TLS3_k127_2162042_4 Protein of unknown function (DUF418) - - - 0.00000000000000000000000000000000000000000000000000000000000001732 237.0
TLS3_k127_2162042_5 O-Antigen ligase - - - 0.000000000000000000000000000000000000000000000000007648 203.0
TLS3_k127_2162042_6 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000000797 197.0
TLS3_k127_2162042_7 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000001478 94.0
TLS3_k127_2180151_0 Class II Aldolase and Adducin N-terminal domain K00068 - 1.1.1.140 0.0 1059.0
TLS3_k127_2180151_1 FGGY family of carbohydrate kinases, N-terminal domain K00848 - 2.7.1.5 3.161e-196 623.0
TLS3_k127_2180151_2 Bacterial PH domain - - - 0.000000000000000000000000000000000004639 147.0
TLS3_k127_2192352_0 Type ii secretion system protein e K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 383.0
TLS3_k127_2192352_1 Type II secretion system (T2SS), protein F - - - 0.0000000000000000000000000000000000000000000006659 188.0
TLS3_k127_2192352_2 type II secretion system - - - 0.000000000000000000000000000000000008791 152.0
TLS3_k127_2192352_3 PFAM TadE family protein - - - 0.00000000000002046 82.0
TLS3_k127_2192352_4 TadE-like protein - - - 0.00000000007103 75.0
TLS3_k127_2200777_0 Sodium:solute symporter family K14387 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 510.0
TLS3_k127_2200777_1 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 399.0
TLS3_k127_2200777_2 Glycosyl hydrolases family 43 K06113 - 3.2.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 332.0
TLS3_k127_2200777_3 Transport permease protein K01992,K18233 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009886 315.0
TLS3_k127_2200777_4 Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001859 250.0
TLS3_k127_2200777_5 ABC transporter K01990 - - 0.00000000000000000000000000000000003274 139.0
TLS3_k127_2231121_0 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002597 280.0
TLS3_k127_2231121_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000008737 175.0
TLS3_k127_2231121_2 Glycosyltransferase - - - 0.0000000000000000000001907 101.0
TLS3_k127_2282278_0 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 293.0
TLS3_k127_2282278_1 Peptidase M50B-like - - - 0.0000000000000000000000000000000000000000000000000000000000003402 217.0
TLS3_k127_2282278_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000002103 93.0
TLS3_k127_2294293_0 glycine betaine K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 497.0
TLS3_k127_2294293_1 ABC-type proline glycine betaine transport system, permease component K05846 - - 0.00000000000000000000000000000000000000000000000000000005744 207.0
TLS3_k127_2294293_2 Binding-protein-dependent transport system inner membrane component K05845,K05846 - - 0.0000000000000008453 84.0
TLS3_k127_2294293_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K03585 - - 0.00004851 54.0
TLS3_k127_2301432_0 Transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009651 406.0
TLS3_k127_2301432_1 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 315.0
TLS3_k127_2301432_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000002608 151.0
TLS3_k127_2301432_3 Protein conserved in bacteria - - - 0.0000000000000000000000000000000001389 146.0
TLS3_k127_2301883_0 Belongs to the arginase family K01476 - 3.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000008217 232.0
TLS3_k127_2301883_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000002413 219.0
TLS3_k127_2301883_2 Putative stress-induced transcription regulator - - - 0.00000000000000000000000000000000000007017 161.0
TLS3_k127_2322230_0 component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1252.0
TLS3_k127_2322230_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 340.0
TLS3_k127_2322230_2 Phospholipid glycerol acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003602 271.0
TLS3_k127_2322230_3 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000004308 169.0
TLS3_k127_2322230_4 Glycine betaine K05845 - - 0.0000000000000000000001794 109.0
TLS3_k127_2322230_5 oxidoreductase activity - - - 0.0000001825 62.0
TLS3_k127_2330347_0 Belongs to the glycosyl hydrolase 13 family - - - 0.0 1312.0
TLS3_k127_2330347_1 Methyl-accepting chemotaxis protein (MCP) signaling domain K02660,K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001266 276.0
TLS3_k127_2330347_2 - - - - 0.00000000000000000000000000000000000000000000000000000008996 200.0
TLS3_k127_2330347_3 Regulatory protein - - - 0.0000000000000000000000000000000003873 134.0
TLS3_k127_2330347_4 helicase activity - - - 0.00000000002902 75.0
TLS3_k127_2338314_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0 1019.0
TLS3_k127_2338314_1 NlpC/P60 family K20742,K21471 - 3.4.14.13 0.00000000000000000000000000000000000000001561 162.0
TLS3_k127_2338314_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000008877 148.0
TLS3_k127_2338314_3 PQQ enzyme repeat - - - 0.000000000000000000000000000000001439 151.0
TLS3_k127_2338314_4 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000419 66.0
TLS3_k127_2361305_0 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 489.0
TLS3_k127_2379074_0 Cytidylyltransferase K00983 - 2.7.7.43 0.0000000000000000000000000000000000000000000000000009622 194.0
TLS3_k127_2379074_1 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000003541 178.0
TLS3_k127_2379074_2 slime layer polysaccharide biosynthetic process - - - 0.00000000000003642 84.0
TLS3_k127_2379074_3 Transglutaminase-like superfamily - - - 0.0000000003601 67.0
TLS3_k127_2381318_0 PFAM Cys Met metabolism K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 508.0
TLS3_k127_2381318_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 339.0
TLS3_k127_2381318_2 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000000000000000004916 183.0
TLS3_k127_2394933_0 Belongs to the long-chain O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 349.0
TLS3_k127_2394933_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005655 254.0
TLS3_k127_2394933_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001735 237.0
TLS3_k127_2394933_3 PFAM GCN5-related N-acetyltransferase K03827 - - 0.0000000000000000000000000000000000000000000000000000000001218 207.0
TLS3_k127_2394933_4 - - - - 0.00000000002303 70.0
TLS3_k127_2397760_0 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 307.0
TLS3_k127_2397760_1 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000001089 215.0
TLS3_k127_2397760_2 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000001212 179.0
TLS3_k127_2397760_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000001779 191.0
TLS3_k127_2397760_4 integration host factor - - - 0.0000000000000000000000000002505 120.0
TLS3_k127_2397760_5 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.0000001116 53.0
TLS3_k127_2397788_0 Domain of unknown function (DUF4872) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 368.0
TLS3_k127_2397788_1 Putative nucleotidyltransferase DUF294 K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 343.0
TLS3_k127_2397788_2 von Willebrand factor, type A - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 336.0
TLS3_k127_2397788_3 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000002647 122.0
TLS3_k127_2397788_4 - - - - 0.000000000392 69.0
TLS3_k127_2401305_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 589.0
TLS3_k127_2401305_1 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 495.0
TLS3_k127_2401305_10 Pfam Amidohydrolase K20810 - 3.5.4.40 0.0000000000000000000000000000000000000000000000000001266 203.0
TLS3_k127_2401305_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000001729 158.0
TLS3_k127_2401305_12 AMP-binding enzyme C-terminal domain K01911,K02549 GO:0003674,GO:0003824,GO:0008150,GO:0008756,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0040007 4.2.1.113,6.2.1.26 0.000000000000000000000000000003942 130.0
TLS3_k127_2401305_13 Pfam:DUF2029 - - - 0.0000000000000000000003889 111.0
TLS3_k127_2401305_14 polysaccharide biosynthetic process K00655,K00721 - 2.3.1.51,2.4.1.83 0.00000000002293 78.0
TLS3_k127_2401305_15 helix_turn_helix, mercury resistance - - - 0.000008985 56.0
TLS3_k127_2401305_2 geranylgeranyl reductase K21401 - 1.3.99.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 397.0
TLS3_k127_2401305_3 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 GO:0008150,GO:0040007 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 334.0
TLS3_k127_2401305_4 chorismate binding enzyme K02552 - 5.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 338.0
TLS3_k127_2401305_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001087 274.0
TLS3_k127_2401305_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000007306 235.0
TLS3_k127_2401305_7 Belongs to the MenA family. Type 1 subfamily K02548 GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000001131 232.0
TLS3_k127_2401305_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000003636 226.0
TLS3_k127_2401305_9 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000001043 217.0
TLS3_k127_2405608_0 Glutathione S-transferase, C-terminal domain K07393 - 1.8.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 496.0
TLS3_k127_2405608_1 Mth938 domain-containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006357,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010941,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045598,GO:0045600,GO:0045893,GO:0045935,GO:0045944,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0060548,GO:0065007,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000000002199 124.0
TLS3_k127_2421120_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 438.0
TLS3_k127_2421120_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 372.0
TLS3_k127_2437045_0 protein conserved in bacteria - - - 3.41e-212 671.0
TLS3_k127_2437045_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 3.866e-199 633.0
TLS3_k127_2437045_2 Dynamin family - GO:0003674,GO:0005215,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015562,GO:0016020,GO:0022857,GO:0030312,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 452.0
TLS3_k127_2437045_3 Heat shock 70 kDa protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008631 444.0
TLS3_k127_2437045_4 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 347.0
TLS3_k127_2437045_5 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000001036 269.0
TLS3_k127_2437045_6 belongs to the thioredoxin family - - - 0.0000000000000000004851 98.0
TLS3_k127_2437045_7 - - - - 0.000000001416 70.0
TLS3_k127_2452322_0 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 491.0
TLS3_k127_2452322_1 Protein of unknown function (DUF418) K07148 - - 0.0000000000000000000000000000000000000000000000000000000000000000004225 244.0
TLS3_k127_2452322_2 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000002963 136.0
TLS3_k127_2452322_3 - - - - 0.0001764 46.0
TLS3_k127_2454081_0 lacI family K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 432.0
TLS3_k127_2454081_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006602 280.0
TLS3_k127_2454081_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000006909 226.0
TLS3_k127_2454081_3 Beta-lactamase - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - 0.0000000000000000000000000000000000000000000003807 176.0
TLS3_k127_2454081_4 CYTH - - - 0.000000000000000000000000000000000000171 147.0
TLS3_k127_2454081_5 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372 5.1.1.3 0.000000000000000000000000000115 118.0
TLS3_k127_2454081_6 - - - - 0.000000000000000000444 93.0
TLS3_k127_2460261_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.188e-256 802.0
TLS3_k127_2460261_1 Dihydroxyacetone kinase K05878 - 2.7.1.121 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 512.0
TLS3_k127_2460261_2 Belongs to the MIP aquaporin (TC 1.A.8) family K02440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 352.0
TLS3_k127_2460261_3 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 314.0
TLS3_k127_2460261_4 Dak2 K05879 - 2.7.1.121 0.0000000000000000000000000000000000000000000000000000000000005946 218.0
TLS3_k127_2460261_5 dihydroxyacetone kinase K05881 - 2.7.1.121 0.0000000000000000000000000001141 121.0
TLS3_k127_2460345_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 611.0
TLS3_k127_2460345_1 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000002138 250.0
TLS3_k127_2460345_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000005109 99.0
TLS3_k127_2462627_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001858 275.0
TLS3_k127_2462627_1 Formamidopyrimidine-DNA glycosylase H2TH domain K05522,K10563 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0003906,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034599,GO:0034641,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0090304,GO:0097159,GO:0097506,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000003742 231.0
TLS3_k127_2465762_0 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 358.0
TLS3_k127_2465762_1 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000826 197.0
TLS3_k127_2465762_2 Glycosyl transferase family 2 - - - 0.00007291 53.0
TLS3_k127_2470159_0 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000001177 187.0
TLS3_k127_2470159_1 Histidine kinase - - - 0.0000000000003552 81.0
TLS3_k127_2470159_2 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000002617 76.0
TLS3_k127_2470159_3 Peptidase family S51 - - - 0.0000001649 61.0
TLS3_k127_2470159_4 Tfp pilus assembly protein FimV - - - 0.0001865 51.0
TLS3_k127_2471309_0 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 482.0
TLS3_k127_2477204_0 Alcohol dehydrogenase GroES-like domain K00001,K00008 - 1.1.1.1,1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 403.0
TLS3_k127_2477204_1 PFAM Bacterial regulatory proteins, lacI family K02529,K05499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 426.0
TLS3_k127_2477204_2 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007831 372.0
TLS3_k127_2477204_3 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 361.0
TLS3_k127_2477204_4 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 332.0
TLS3_k127_2477204_5 B3/4 domain - - - 0.000000000000000000000000000000000000000000000000000000000004841 216.0
TLS3_k127_2477204_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000004609 154.0
TLS3_k127_2477204_7 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000008551 118.0
TLS3_k127_2477204_8 AzlC protein - - - 0.00000007626 64.0
TLS3_k127_2483714_0 Amidinotransferase K01478 - 3.5.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 370.0
TLS3_k127_2483714_1 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000009981 205.0
TLS3_k127_2483714_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.0000000000000000000000000000000000005538 153.0
TLS3_k127_2488395_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 597.0
TLS3_k127_2488395_1 ANTAR domain protein - - - 0.000000000000000000000000000000000000000000003866 179.0
TLS3_k127_2488395_2 Protein of unknown function (DUF983) - - - 0.0000000000000000000000392 111.0
TLS3_k127_2488395_3 His Kinase A (phosphoacceptor) domain - - - 0.000001167 61.0
TLS3_k127_2495976_0 hydrolase, family 3 K05349 - 3.2.1.21 4.379e-312 965.0
TLS3_k127_2532947_0 ATPases associated with a variety of cellular activities K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 465.0
TLS3_k127_2532947_1 DegT/DnrJ/EryC1/StrS aminotransferase family K13010,K19430 - 2.6.1.102 0.00000000000000000000000000000000000001992 155.0
TLS3_k127_2532947_2 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000000000000008685 106.0
TLS3_k127_2539419_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 509.0
TLS3_k127_2539419_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 408.0
TLS3_k127_2539419_2 transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000005249 192.0
TLS3_k127_2541930_0 FAD linked oxidase domain protein K16653 GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576 1.1.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 402.0
TLS3_k127_2541930_1 3-dehydroquinate synthase K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 397.0
TLS3_k127_2541930_2 phosphatidylinositol metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 380.0
TLS3_k127_2541930_3 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 319.0
TLS3_k127_2541930_4 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 310.0
TLS3_k127_2541930_5 KR domain K16652 - 1.1.1.333 0.0000000000000000000000000000000000000000000000000000000000000000000021 246.0
TLS3_k127_2541930_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00007233 56.0
TLS3_k127_2546862_0 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 403.0
TLS3_k127_2546862_1 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 364.0
TLS3_k127_2546862_10 Acetyltransferase (GNAT) family K22477 - 2.3.1.1 0.0000000000006545 75.0
TLS3_k127_2546862_11 - - - - 0.000000000002569 69.0
TLS3_k127_2546862_12 Putative zinc-finger - - - 0.000001846 60.0
TLS3_k127_2546862_2 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007345 290.0
TLS3_k127_2546862_3 Alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000003288 246.0
TLS3_k127_2546862_4 Haloacid dehalogenase, type II K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000003126 200.0
TLS3_k127_2546862_5 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000355 175.0
TLS3_k127_2546862_6 Phosphodiester glycosidase - - - 0.00000000000000000000000000001101 137.0
TLS3_k127_2546862_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000002391 122.0
TLS3_k127_2546862_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000001077 109.0
TLS3_k127_2546862_9 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000001257 88.0
TLS3_k127_2559527_0 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 446.0
TLS3_k127_2559527_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 329.0
TLS3_k127_2559527_2 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004294 247.0
TLS3_k127_2561920_0 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 5.321e-273 849.0
TLS3_k127_2561920_1 DNA RNA non-specific endonuclease K01173 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007749 419.0
TLS3_k127_2561920_2 Belongs to the glycosyl hydrolase family 6 K19668 - 3.2.1.91 0.0000000000000000000000000001685 128.0
TLS3_k127_2561920_3 cellulose binding - - - 0.000000000005715 79.0
TLS3_k127_2561920_4 Belongs to the glycosyl hydrolase 12 (cellulase H) family - - - 0.00000000001798 76.0
TLS3_k127_2568907_0 GMC oxidoreductase K00108 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 460.0
TLS3_k127_2568907_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001653 244.0
TLS3_k127_2568907_2 Domain of unknown function (DUF1707) - - - 0.00000000001699 72.0
TLS3_k127_2568907_3 Predicted integral membrane protein (DUF2269) - - - 0.000002183 59.0
TLS3_k127_2573181_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 389.0
TLS3_k127_2573181_1 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.6 0.000000000000001735 82.0
TLS3_k127_2576357_0 PFAM PHP domain K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 508.0
TLS3_k127_2576357_1 Glycosyltransferase family 28 N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007021 280.0
TLS3_k127_2576357_2 glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000009133 209.0
TLS3_k127_2576357_3 Methylpurine-DNA glycosylase (MPG) K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.000000000000000000000000000000000000000000000002359 191.0
TLS3_k127_2593502_0 TonB-dependent receptor plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000006447 207.0
TLS3_k127_2593502_1 nicotinamide mononucleotide transporter K03811 - - 0.000000000000000000000000000000000000000000000004162 181.0
TLS3_k127_2593502_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000129 112.0
TLS3_k127_2593502_3 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.0000000000000000000000001587 108.0
TLS3_k127_2593502_4 Phosphotransferase enzyme family K07251 - 2.7.1.89 0.0000000000000000000001944 110.0
TLS3_k127_2593502_5 YKOF-related Family - - - 0.000000000000000007927 89.0
TLS3_k127_2593590_0 ABC-type sugar transport system periplasmic component K02058,K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 463.0
TLS3_k127_2593590_1 xylulokinase activity K00848,K00851,K00854,K00862 - 2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 462.0
TLS3_k127_2593590_2 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10562 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008204 406.0
TLS3_k127_2593590_3 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 323.0
TLS3_k127_2593590_4 PFAM Xylose isomerase-like TIM barrel K18910 - 5.1.3.30,5.1.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 311.0
TLS3_k127_2593590_5 inositol 2-dehydrogenase activity K16043 - 1.1.1.370 0.000000000000000000000000000000000000000000000000000000000000000000008044 258.0
TLS3_k127_2593590_6 Glucose-6-phosphate isomerase (GPI) K06859 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000144 211.0
TLS3_k127_2593590_7 PFAM short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000001051 185.0
TLS3_k127_2593590_8 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000003997 129.0
TLS3_k127_2606212_0 PFAM Hydantoinase oxoprolinase - - - 2.718e-244 772.0
TLS3_k127_2606212_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 2.297e-227 715.0
TLS3_k127_2606212_2 Bacterial extracellular solute-binding protein K07114 - - 0.000000000000000000000000000000000000000000000000000002756 196.0
TLS3_k127_2606212_3 - - - - 0.00000000000000000000711 102.0
TLS3_k127_2606397_0 Pyridine nucleotide-disulphide oxidoreductase K21567 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 452.0
TLS3_k127_2606397_1 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 416.0
TLS3_k127_2606397_10 Putative regulatory protein - - - 0.00000000000000000605 86.0
TLS3_k127_2606397_11 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000002207 85.0
TLS3_k127_2606397_12 - - - - 0.00000000000008561 79.0
TLS3_k127_2606397_2 reductase K00002,K06221,K06222,K17743 GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008106,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0047681,GO:0051596,GO:0055114,GO:0071704,GO:1901575,GO:1990002 1.1.1.2,1.1.1.307,1.1.1.346 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001285 279.0
TLS3_k127_2606397_3 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000253 177.0
TLS3_k127_2606397_4 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000126 131.0
TLS3_k127_2606397_5 PadR family transcriptional regulator K10947 - - 0.000000000000000000000000000001275 125.0
TLS3_k127_2606397_6 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.000000000000000000000004801 110.0
TLS3_k127_2606397_7 Amino acid-binding - - - 0.0000000000000000000001358 106.0
TLS3_k127_2606397_8 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000005382 105.0
TLS3_k127_2606397_9 Protein of unknown function (DUF952) - - - 0.00000000000000000000304 104.0
TLS3_k127_260807_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 1.323e-222 708.0
TLS3_k127_260807_1 Catalase domain protein K03781 - 1.11.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 600.0
TLS3_k127_260807_10 Exonuclease K03546 - - 0.00000000000000000000000000000000000000000013 165.0
TLS3_k127_260807_11 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000001968 169.0
TLS3_k127_260807_12 BON domain - - - 0.0000000000000002648 93.0
TLS3_k127_260807_13 Protein of unknown function DUF86 - - - 0.00002681 51.0
TLS3_k127_260807_2 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 484.0
TLS3_k127_260807_3 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 408.0
TLS3_k127_260807_4 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008381 279.0
TLS3_k127_260807_5 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000003407 265.0
TLS3_k127_260807_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000009047 218.0
TLS3_k127_260807_7 PFAM DoxX family protein K16937 - 1.8.5.2 0.0000000000000000000000000000000000000000000000000000000000164 214.0
TLS3_k127_260807_8 COGs COG2380 conserved - - - 0.00000000000000000000000000000000000000000000000000000005291 209.0
TLS3_k127_260807_9 Belongs to the Fur family K03711,K22297 - - 0.00000000000000000000000000000000000000000000001744 175.0
TLS3_k127_2614420_0 Pfam:Pyridox_oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001093 276.0
TLS3_k127_2614420_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000002358 215.0
TLS3_k127_2614420_2 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000006234 191.0
TLS3_k127_2614420_3 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000001948 85.0
TLS3_k127_2629103_0 DEAD DEAH box helicase K03724 - - 6.831e-221 698.0
TLS3_k127_2629103_1 Histidine kinase K00936 GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007294 439.0
TLS3_k127_2629103_2 RNA polymerase K03090 GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 301.0
TLS3_k127_2629103_3 DEAD DEAH box helicase domain protein K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 296.0
TLS3_k127_2629103_4 Diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000002209 225.0
TLS3_k127_2629103_5 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000005203 208.0
TLS3_k127_2629103_6 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000004396 140.0
TLS3_k127_2629103_7 NUDIX domain - - - 0.000000000000000000000000003193 129.0
TLS3_k127_2629103_8 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000000002537 82.0
TLS3_k127_2629103_9 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00004161 57.0
TLS3_k127_263958_0 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 466.0
TLS3_k127_263958_1 endo-1,4-beta-xylanase activity K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 369.0
TLS3_k127_263958_10 transcriptional - - - 0.0000000000000000000000000000000000007976 141.0
TLS3_k127_263958_11 Putative zinc-finger - - - 0.000000000000002827 81.0
TLS3_k127_263958_2 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 322.0
TLS3_k127_263958_3 Bacterial regulatory proteins, lacI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006388 280.0
TLS3_k127_263958_4 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006798 268.0
TLS3_k127_263958_5 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000231 240.0
TLS3_k127_263958_6 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000001867 224.0
TLS3_k127_263958_7 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000001279 184.0
TLS3_k127_263958_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000008447 169.0
TLS3_k127_263958_9 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000006989 164.0
TLS3_k127_2659453_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 559.0
TLS3_k127_2659453_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 477.0
TLS3_k127_2659453_10 - - - - 0.000000000001211 78.0
TLS3_k127_2659453_11 - - - - 0.0001764 46.0
TLS3_k127_2659453_2 DNA polymerase beta thumb K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 439.0
TLS3_k127_2659453_3 Periplasmic binding protein domain K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 426.0
TLS3_k127_2659453_4 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 338.0
TLS3_k127_2659453_5 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 327.0
TLS3_k127_2659453_6 Pirin K06911 - - 0.00000000000000000000000000000000000000000000000000006349 199.0
TLS3_k127_2659453_7 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.0000000000000000000000000006685 119.0
TLS3_k127_2698419_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009064 242.0
TLS3_k127_2698419_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000008041 191.0
TLS3_k127_2707169_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 1.785e-307 956.0
TLS3_k127_2707169_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 563.0
TLS3_k127_2707169_2 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 544.0
TLS3_k127_2707169_3 alcohol dehydrogenase K18382 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 507.0
TLS3_k127_2707169_4 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 322.0
TLS3_k127_2707169_5 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000002219 220.0
TLS3_k127_2707169_6 metal-sulfur cluster biosynthetic enzyme - - - 0.0000000000000000000000000000000000000000000000000009921 191.0
TLS3_k127_2707169_7 pyridoxamine 5-phosphate K07006 - - 0.00000000000000000000000000000000000000000001688 183.0
TLS3_k127_2714023_0 Nucleotidyl transferase K00966,K00992 - 2.7.7.13,2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 314.0
TLS3_k127_2714023_1 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000001384 183.0
TLS3_k127_2719552_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 522.0
TLS3_k127_2719552_1 MlrC C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 391.0
TLS3_k127_2719552_2 regulator IclR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000863 262.0
TLS3_k127_2719552_3 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.000000000000000000000000000000000000000000000000000000000000000000002963 248.0
TLS3_k127_2719552_4 transcriptional regulator K13641 - - 0.00000000000000000000000000000000000000000000000000000000000000009293 232.0
TLS3_k127_2719552_5 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000009565 213.0
TLS3_k127_2719552_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000009135 158.0
TLS3_k127_2722928_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 454.0
TLS3_k127_2722928_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007896 273.0
TLS3_k127_2722928_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000009403 259.0
TLS3_k127_2722928_3 Mut7-C ubiquitin K09122 - - 0.000000000000000000000000000000000000000000000000000000000307 231.0
TLS3_k127_2722928_4 Belongs to the UPF0312 family - - - 0.00000000000000002021 90.0
TLS3_k127_2725954_0 Bacterial transcription activator, effector binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000248 261.0
TLS3_k127_2725954_1 amine dehydrogenase activity K08642 - - 0.00000000000000000000000000000000000000000000000000000000000000000003057 245.0
TLS3_k127_2725954_2 Ferredoxin - - - 0.00000000000000000000000000000000000000000000003871 178.0
TLS3_k127_2725954_3 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000009095 179.0
TLS3_k127_2725954_4 Arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.000000000000000000000000000000000000000019 166.0
TLS3_k127_2725954_5 glyoxalase - - - 0.00000000000000009622 89.0
TLS3_k127_2728649_0 FGGY family of carbohydrate kinases, N-terminal domain K00853 - 2.7.1.16 2.33e-216 702.0
TLS3_k127_2728649_1 Transcriptional regulator K11531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 305.0
TLS3_k127_2728649_2 Periplasmic binding protein domain K10559 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006042 277.0
TLS3_k127_2728649_3 L-ribulose-5-phosphate 4-epimerase K03077 - 5.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000328 261.0
TLS3_k127_2728649_4 Belongs to the binding-protein-dependent transport system permease family K10560 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001574 263.0
TLS3_k127_2728649_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000002698 253.0
TLS3_k127_2728649_6 Belongs to the binding-protein-dependent transport system permease family K10561 - - 0.0000000000000000000000000000000000000000000000000000001676 219.0
TLS3_k127_2728649_7 PFAM Sugar isomerase (SIS) K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000002877 199.0
TLS3_k127_2740356_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 599.0
TLS3_k127_2740356_1 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 319.0
TLS3_k127_2740356_2 possibly involved in thiol disulfide interchange. contains PS00013 prokaryotic membrane lipoprotein lipid attachment site, N-term signal pepitde sequence and PS00194 thioredoxin family active site - - - 0.00000000000000000001475 94.0
TLS3_k127_2740464_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 324.0
TLS3_k127_2740464_1 Short-chain Dehydrogenase reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009769 289.0
TLS3_k127_2740464_2 Transcriptional regulator - - - 0.00001083 51.0
TLS3_k127_2740586_0 Aminotransferase K00812,K14267 - 2.6.1.1,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 494.0
TLS3_k127_2740586_1 ABC transporter, ATP-binding protein K02028,K02029 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 331.0
TLS3_k127_2740586_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 337.0
TLS3_k127_2740586_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002105 286.0
TLS3_k127_2740586_4 ABC transporter K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000005538 222.0
TLS3_k127_2744071_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0008150,GO:0040007 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 560.0
TLS3_k127_2744071_1 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 363.0
TLS3_k127_2744071_2 Domain of unknown function (DUF3291) - - - 0.0000000000000000000000000000000000000000000000000000000000004713 218.0
TLS3_k127_2744071_3 Sulfotransferase domain - - - 0.000000000000007165 85.0
TLS3_k127_2744909_0 WD-40 repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 487.0
TLS3_k127_2744909_1 Bacterial extracellular solute-binding protein K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005042 265.0
TLS3_k127_2751192_0 PFAM carboxyl transferase K18472 - 2.1.3.15,6.4.1.2,6.4.1.3 2.201e-204 647.0
TLS3_k127_2751192_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 377.0
TLS3_k127_2751192_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000006473 224.0
TLS3_k127_2751918_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 5.378e-226 712.0
TLS3_k127_2751918_1 helix_turn_helix, Deoxyribose operon repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 414.0
TLS3_k127_2751918_2 Periplasmic binding protein domain K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 415.0
TLS3_k127_2751918_3 Transcriptional regulator K07506,K07720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 399.0
TLS3_k127_2751918_4 Methyltransferase small domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003812 232.0
TLS3_k127_2751918_5 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000004883 213.0
TLS3_k127_2751918_6 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000002635 209.0
TLS3_k127_2751918_7 Catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate K03784 - 2.4.2.1 0.00000000000000000000000000000000000000000000002413 173.0
TLS3_k127_2751918_8 Protein of unknown function (DUF861) - - - 0.0000000000000000000001078 102.0
TLS3_k127_2775842_0 ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008753 278.0
TLS3_k127_2775842_1 - - - - 0.00000001698 66.0
TLS3_k127_2776438_0 PFAM HhH-GPD family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006949 317.0
TLS3_k127_2776438_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003428 272.0
TLS3_k127_2776438_2 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001663 254.0
TLS3_k127_2776438_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000003313 73.0
TLS3_k127_2778472_0 Na H antiporter - - - 2.131e-201 647.0
TLS3_k127_2778472_1 40-residue YVTN family beta-propeller - - - 0.00000000000000000000000000000000000003312 161.0
TLS3_k127_2778472_2 Universal stress protein family - - - 0.0000000000000000000000000000000007623 149.0
TLS3_k127_2778472_3 Elongation factor SelB, winged helix K03833 - - 0.000000000000000002217 93.0
TLS3_k127_2795102_0 PFAM ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 398.0
TLS3_k127_2795102_1 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000003542 174.0
TLS3_k127_2795102_2 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000000001144 144.0
TLS3_k127_2797270_0 Cellulase (glycosyl hydrolase family 5) K01218 - 3.2.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 535.0
TLS3_k127_2797270_1 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 349.0
TLS3_k127_2797270_2 EAL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 292.0
TLS3_k127_2797270_3 MobA-like NTP transferase domain K03752 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000168 214.0
TLS3_k127_2801481_0 Vault protein inter-alpha-trypsin domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 596.0
TLS3_k127_2801481_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 394.0
TLS3_k127_2801481_2 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008467 280.0
TLS3_k127_2801481_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001112 259.0
TLS3_k127_2801481_4 Diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000003832 212.0
TLS3_k127_2801481_5 Sortase family K07284 - 3.4.22.70 0.00000000000000000000000000000000000000000000002324 184.0
TLS3_k127_2801481_6 MerR HTH family regulatory protein - - - 0.00000000000000000000000006103 115.0
TLS3_k127_2801481_7 Histidine kinase - - - 0.0000002356 53.0
TLS3_k127_2825130_0 Transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000006565 233.0
TLS3_k127_2826452_0 cellular response to dsDNA K11211,K19302 - 2.7.1.166,3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 510.0
TLS3_k127_2826452_1 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002706 284.0
TLS3_k127_2826452_2 Substrate binding domain of ABC-type glycine betaine transport system K05845 - - 0.0000000000000000000000000000000000000000005544 166.0
TLS3_k127_2826452_4 Lysylphosphatidylglycerol synthase TM region K07027,K19302 - 3.6.1.27 0.0001065 48.0
TLS3_k127_2829405_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0008150,GO:0040007 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 367.0
TLS3_k127_2829405_1 cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000008344 240.0
TLS3_k127_2829405_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000005852 241.0
TLS3_k127_2829405_3 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000004544 168.0
TLS3_k127_2829405_4 FCD - - - 0.0000000000000000000000000000000000000001631 159.0
TLS3_k127_2829405_5 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.000000000000000000000002674 108.0
TLS3_k127_2829405_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000006039 104.0
TLS3_k127_2829405_7 Glucose Sorbosone dehydrogenase - - - 0.000000000000000000002673 94.0
TLS3_k127_2829405_8 ThiS family K03154 - - 0.000001345 58.0
TLS3_k127_2836660_0 ABC transporter transmembrane region K06147,K06148 - - 9.842e-314 977.0
TLS3_k127_2836660_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000001046 274.0
TLS3_k127_2836660_2 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000003149 177.0
TLS3_k127_2836660_3 CoA binding domain K06929 - - 0.00000000000000000000000000000000000003554 154.0
TLS3_k127_2836660_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000001044 98.0
TLS3_k127_2836660_5 - - - - 0.0000008647 57.0
TLS3_k127_2836660_6 Cro/C1-type HTH DNA-binding domain - - - 0.000007489 54.0
TLS3_k127_2841669_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 3.246e-277 870.0
TLS3_k127_2841669_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 440.0
TLS3_k127_284642_0 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000002279 184.0
TLS3_k127_284642_1 Cell envelope-related transcriptional attenuator domain - - - 0.0000000000000000000000001276 119.0
TLS3_k127_284642_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000002912 89.0
TLS3_k127_284642_3 - - - - 0.000000005107 66.0
TLS3_k127_284642_4 - - - - 0.0007647 44.0
TLS3_k127_2853455_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 521.0
TLS3_k127_2853455_1 AAA domain - GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009405,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044315,GO:0044419,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004457 284.0
TLS3_k127_2853455_2 alpha-ribazole phosphatase activity K02226,K15634,K22305 - 3.1.3.3,3.1.3.73,5.4.2.12 0.000000000000000000000000000000000000000001539 166.0
TLS3_k127_2853455_3 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.0000000002075 66.0
TLS3_k127_288388_0 SAICAR synthetase K01923,K01945 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.0000000000000000000000000000461 117.0
TLS3_k127_288388_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000001659 93.0
TLS3_k127_2893418_0 phosphoheptose isomerase K03271,K15669 - 2.7.7.71,5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000001917 231.0
TLS3_k127_2893418_1 Cytidylyltransferase-like K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000002176 197.0
TLS3_k127_2893418_2 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000005266 165.0
TLS3_k127_2904396_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 398.0
TLS3_k127_2904396_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 338.0
TLS3_k127_2904396_2 PFAM sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000006778 222.0
TLS3_k127_2904396_3 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000003362 181.0
TLS3_k127_2904396_4 PFAM lipopolysaccharide biosynthesis protein K08252,K08253 - 2.7.10.1,2.7.10.2 0.000001127 58.0
TLS3_k127_2916443_0 organic phosphonate transport K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 359.0
TLS3_k127_2916443_1 ABC-type phosphate phosphonate transport system, ATPase component K02041 - 3.6.3.28 0.000000000000000000000000000000000000000000000000000000000000000000000000007326 259.0
TLS3_k127_2916443_2 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005706 257.0
TLS3_k127_2916443_3 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000001315 124.0
TLS3_k127_2918517_0 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 295.0
TLS3_k127_2918517_1 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000002951 72.0
TLS3_k127_2918517_2 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.00001236 56.0
TLS3_k127_2919876_0 PFAM amidohydrolase 2 K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003296 276.0
TLS3_k127_2919876_1 mandelate racemase muconate lactonizing K01856,K02549 - 4.2.1.113,5.5.1.1 0.00000000000002437 79.0
TLS3_k127_2919876_2 carboxymuconolactone decarboxylase - - - 0.000000000654 70.0
TLS3_k127_2927348_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 436.0
TLS3_k127_2927348_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000184 240.0
TLS3_k127_2927348_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.7.1.148 0.0000000000004547 74.0
TLS3_k127_2945073_0 PFAM extracellular solute-binding protein family 5 K02035 - - 1.795e-212 674.0
TLS3_k127_2945073_1 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 511.0
TLS3_k127_2945073_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 408.0
TLS3_k127_2945073_3 ABC-type dipeptide oligopeptide nickel transport system, permease component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 387.0
TLS3_k127_2945073_4 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000004091 254.0
TLS3_k127_2945073_5 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000005613 235.0
TLS3_k127_2951793_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 579.0
TLS3_k127_2951793_1 COGs COG1620 L-lactate permease K03303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001871 273.0
TLS3_k127_2956095_0 Belongs to the TPP enzyme family K03336 - 3.7.1.22 1.971e-288 898.0
TLS3_k127_2956095_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 3.232e-257 803.0
TLS3_k127_2956095_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 451.0
TLS3_k127_2956095_3 ABC transporter substrate-binding protein K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009904 413.0
TLS3_k127_2956095_4 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 398.0
TLS3_k127_2956095_5 dehydratase K03335 - 4.2.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 355.0
TLS3_k127_2956095_6 KduI/IolB family K03337 - 5.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 302.0
TLS3_k127_2956095_7 Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 321.0
TLS3_k127_2966009_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 4.019e-241 763.0
TLS3_k127_2967068_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 9.387e-256 816.0
TLS3_k127_2967068_1 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 3.565e-227 725.0
TLS3_k127_2967068_10 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000005563 256.0
TLS3_k127_2967068_11 alpha-ribazole phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000002843 240.0
TLS3_k127_2967068_12 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000538 196.0
TLS3_k127_2967068_13 transcriptional regulator - - - 0.00000000000000000000000000000000000000001851 162.0
TLS3_k127_2967068_2 Acyl-coa dehydrogenase K00249 - 1.3.8.7 2.056e-194 635.0
TLS3_k127_2967068_3 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 2.889e-194 619.0
TLS3_k127_2967068_4 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008178 538.0
TLS3_k127_2967068_5 PFAM acyl-CoA dehydrogenase domain protein K00252 - 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 479.0
TLS3_k127_2967068_6 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 390.0
TLS3_k127_2967068_7 COGs COG2133 Glucose sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 306.0
TLS3_k127_2967068_8 S-adenosyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003303 286.0
TLS3_k127_2967068_9 o-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008763 247.0
TLS3_k127_2977465_0 Belongs to the AAA ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 598.0
TLS3_k127_2977465_1 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 310.0
TLS3_k127_2977465_2 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002894 272.0
TLS3_k127_2977465_3 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002146 264.0
TLS3_k127_2977465_4 Transglycosylase-like domain protein K21688 GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016 - 0.00000000002526 64.0
TLS3_k127_2977465_5 Transglycosylase-like domain protein K21688 GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016 - 0.00000000002526 64.0
TLS3_k127_2985459_0 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001311 249.0
TLS3_k127_2985459_1 Transcriptional regulator - - - 0.000000000000000000000000000000002711 134.0
TLS3_k127_2985459_2 TIGRFAM conserved - - - 0.0000000000000000000000000000004952 137.0
TLS3_k127_2992781_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 563.0
TLS3_k127_2992781_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 345.0
TLS3_k127_2992781_2 - - - - 0.000000000000000000000000000000000000000000000000000005515 201.0
TLS3_k127_2992781_3 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000153 169.0
TLS3_k127_2992781_4 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000001414 132.0
TLS3_k127_2992781_5 ATPase, P-type transporting, HAD superfamily, subfamily IC - - - 0.0000001336 57.0
TLS3_k127_2992781_6 Lysylphosphatidylglycerol synthase TM region K07027,K20468 - - 0.000000134 56.0
TLS3_k127_2992781_7 Bacterial regulatory proteins, tetR family - - - 0.0002695 52.0
TLS3_k127_2993080_0 KR domain K00218 - 1.3.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000528 281.0
TLS3_k127_2993080_1 Peptidase family S49 K04773,K04774 - - 0.00000000000000000000000000000000000000000000000000000000000001035 224.0
TLS3_k127_2993080_2 Peptidase M50 - - - 0.00000000000000000000000000000000000000004286 168.0
TLS3_k127_2997069_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.389e-218 691.0
TLS3_k127_2997069_1 May be involved in recombinational repair of damaged DNA K03631 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 309.0
TLS3_k127_3005914_0 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 572.0
TLS3_k127_3005914_1 SnoaL-like domain K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 508.0
TLS3_k127_3005914_2 phosphoserine phosphatase K01079 GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0004722,GO:0005488,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016597,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0031406,GO:0036094,GO:0036211,GO:0040007,GO:0042578,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 432.0
TLS3_k127_3005914_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 409.0
TLS3_k127_3005914_4 PFAM Aldehyde dehydrogenase K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000002347 248.0
TLS3_k127_3005914_5 Trypsin-like serine protease with C-terminal PDZ domain - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000003008 214.0
TLS3_k127_3005914_6 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0000000000000000000000000000000000000000000000000004749 194.0
TLS3_k127_3023655_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007511 452.0
TLS3_k127_3023655_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.00000000000000000000000000008279 122.0
TLS3_k127_3023655_2 Competence protein ComEC K02238 - - 0.0000000000000000000000009858 120.0
TLS3_k127_3023655_3 Reductase C-terminal K05297 - 1.18.1.1 0.0000000000001936 76.0
TLS3_k127_3023655_4 DNA-directed DNA polymerase activity K02340 - 2.7.7.7 0.0000000001006 73.0
TLS3_k127_3031390_0 ABC transporter transmembrane region K02021,K06147,K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 498.0
TLS3_k127_3031390_1 ABC transporter related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 455.0
TLS3_k127_3031390_2 PAS domain - - - 0.000000000000000000000000000000000000000000000000000003689 211.0
TLS3_k127_3031390_3 PFAM HhH-GPD family protein - - - 0.000000000000000000000000000000000000000000000000000008794 194.0
TLS3_k127_3031390_4 protein conserved in bacteria - - - 0.000001435 54.0
TLS3_k127_3042912_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 1.953e-226 720.0
TLS3_k127_3042912_1 HIT family hydrolase, diadenosine tetraphosphate hydrolase K19710 GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000003963 220.0
TLS3_k127_3042912_2 CDP-alcohol phosphatidyltransferase K00995,K00999 GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.11,2.7.8.5 0.0000000000000000000000000000002312 134.0
TLS3_k127_304391_0 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000085 436.0
TLS3_k127_304391_1 acyl-CoA dehydrogenase K00248,K11410 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 433.0
TLS3_k127_304391_2 Methylamine utilisation protein MauE - - - 0.00000000000006668 80.0
TLS3_k127_304391_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0009311 51.0
TLS3_k127_3056566_0 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 452.0
TLS3_k127_3056566_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 405.0
TLS3_k127_3056566_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005078 283.0
TLS3_k127_3056566_3 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000000000000001693 206.0
TLS3_k127_3056566_4 DoxX-like family - - - 0.0000000000000000005943 91.0
TLS3_k127_3057053_0 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 553.0
TLS3_k127_3057053_1 Fumarylacetoacetase N-terminal K01555 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 409.0
TLS3_k127_3057053_2 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 391.0
TLS3_k127_3057053_3 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008488 289.0
TLS3_k127_3057053_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000003573 187.0
TLS3_k127_3057053_5 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000007974 186.0
TLS3_k127_3070613_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 462.0
TLS3_k127_3070613_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 312.0
TLS3_k127_3070613_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000001983 132.0
TLS3_k127_3070613_3 Diguanylate cyclase - - - 0.0000000000000000000000000003582 132.0
TLS3_k127_3070613_4 HDOD domain - - - 0.0000000000000001003 88.0
TLS3_k127_3072412_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 522.0
TLS3_k127_3072412_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000003464 266.0
TLS3_k127_3078557_0 decarboxylase K13745 - 4.1.1.86 1.509e-200 638.0
TLS3_k127_3078557_1 Predicted membrane protein (DUF2254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 486.0
TLS3_k127_3078557_2 L-lysine 6-monooxygenase (NADPH-requiring) K03897 - 1.14.13.59 0.000000000000000000000000000000000000000000000000000000007215 204.0
TLS3_k127_3087348_0 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 533.0
TLS3_k127_3087348_1 ATPases associated with a variety of cellular activities K01990,K11050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 370.0
TLS3_k127_3087348_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001585 282.0
TLS3_k127_3087348_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000005208 240.0
TLS3_k127_3087348_4 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000001477 209.0
TLS3_k127_3087348_5 Domain of unknown function (DUF4143) K07133 - - 0.00000000000009588 72.0
TLS3_k127_3087348_6 - - - - 0.00004516 53.0
TLS3_k127_308876_0 epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 359.0
TLS3_k127_308876_1 Glycosyl transferase 4-like domain - - - 0.000000000000000000000001838 109.0
TLS3_k127_3095803_0 Fn3 associated - - - 3.006e-204 664.0
TLS3_k127_3102104_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 477.0
TLS3_k127_3102104_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 387.0
TLS3_k127_3102104_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000006956 224.0
TLS3_k127_3102104_3 alpha-ribazole phosphatase activity K15634,K22306 - 3.1.3.85,5.4.2.12 0.00000000000000000000000000000000000001579 151.0
TLS3_k127_3102104_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000416 119.0
TLS3_k127_3102104_5 - - - - 0.000000000000000000535 97.0
TLS3_k127_3102104_6 - - - - 0.00004116 48.0
TLS3_k127_3104316_0 Fructose-bisphosphate aldolase, class II K01624 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 544.0
TLS3_k127_3104316_1 threonine--tRNA ligase K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 463.0
TLS3_k127_3104316_2 IrrE N-terminal-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 444.0
TLS3_k127_3104316_3 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 342.0
TLS3_k127_3104316_4 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000000000000000000000000001388 191.0
TLS3_k127_3104316_5 Putative inner membrane exporter, YdcZ K09936 - - 0.0000000000000000000000000000000009238 135.0
TLS3_k127_3104316_6 Histidine kinase - - - 0.0000000000000000000000000000001036 145.0
TLS3_k127_3104316_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000008317 104.0
TLS3_k127_310785_0 Molybdopterin oxidoreductase Fe4S4 domain K00372,K02567 - - 8.626e-255 826.0
TLS3_k127_310785_1 Major Facilitator Superfamily K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 456.0
TLS3_k127_310785_2 nitrite transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 301.0
TLS3_k127_310785_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008714 273.0
TLS3_k127_310785_4 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002243 264.0
TLS3_k127_310785_5 FMN reductase K00299 - 1.5.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000001961 255.0
TLS3_k127_310785_6 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000239 149.0
TLS3_k127_310785_7 - - - - 0.000000004458 62.0
TLS3_k127_3125149_0 Alpha-galactosidase K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 511.0
TLS3_k127_3125149_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 509.0
TLS3_k127_3125149_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000004542 139.0
TLS3_k127_312574_0 Class II Aldolase and Adducin N-terminal domain K00068 - 1.1.1.140 1.423e-316 977.0
TLS3_k127_312574_1 Isomerase K01820 - 5.3.1.14 2.796e-195 619.0
TLS3_k127_312574_2 L-rhamnose mutarotase K03534 - 5.1.3.32 0.000000000000000000000000000000000000000000007368 165.0
TLS3_k127_3129085_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 375.0
TLS3_k127_3129085_1 TIGRFAM 2-oxoglutarate dehydrogenase, E2 component K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 369.0
TLS3_k127_3129085_2 mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005799 260.0
TLS3_k127_3129085_3 Biotin/lipoate A/B protein ligase family K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000001028 170.0
TLS3_k127_3131937_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 561.0
TLS3_k127_3131937_1 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 443.0
TLS3_k127_3145914_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 444.0
TLS3_k127_3145914_1 Homoserine dehydrogenase K00003,K12524 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 441.0
TLS3_k127_3145914_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 427.0
TLS3_k127_3145914_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 390.0
TLS3_k127_3145914_4 branched-chain amino acid - - - 0.000000000000000000000000000000000000000000000000000000002559 209.0
TLS3_k127_3145914_5 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000000007926 158.0
TLS3_k127_3145914_6 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000001085 139.0
TLS3_k127_3145914_7 Branched-chain amino acid transport protein (AzlD) - - - 0.000000000000002797 87.0
TLS3_k127_3145914_8 COG1278 Cold shock proteins K03704 - - 0.00000000000004579 76.0
TLS3_k127_3145914_9 Glycosylase K05522 - 4.2.99.18 0.000000001594 59.0
TLS3_k127_3146467_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 434.0
TLS3_k127_3146467_1 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 381.0
TLS3_k127_3158402_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 4.538e-222 698.0
TLS3_k127_3158402_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001663 259.0
TLS3_k127_3162239_0 Ribonucleotide reductase, barrel domain K00525 - 1.17.4.1 7.034e-293 915.0
TLS3_k127_3162239_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 334.0
TLS3_k127_3162239_2 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000001031 212.0
TLS3_k127_3162239_3 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000001278 115.0
TLS3_k127_3167815_0 peptidase K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007523 419.0
TLS3_k127_3167815_1 PFAM alpha beta hydrolase fold K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000002014 246.0
TLS3_k127_3167815_2 RHS Repeat - - - 0.0000003049 59.0
TLS3_k127_3171399_0 Phosphomethylpyrimidine kinase - - - 0.00000000000000000000000000000000000000000000000000007709 198.0
TLS3_k127_3171399_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000002254 62.0
TLS3_k127_3172121_0 Diacylglycerol kinase K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 400.0
TLS3_k127_3172121_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004042 278.0
TLS3_k127_3172121_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000002129 215.0
TLS3_k127_3172121_3 SnoaL-like domain - - - 0.00000000000000000005725 92.0
TLS3_k127_3172121_4 Prokaryotic phospholipase A2 - - - 0.0000000005824 68.0
TLS3_k127_3183876_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000002286 183.0
TLS3_k127_3183876_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000005636 173.0
TLS3_k127_3183876_2 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000002421 93.0
TLS3_k127_3195031_0 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000000000003324 186.0
TLS3_k127_3195031_1 COG0433 Predicted ATPase - - - 0.0000000000000008853 91.0
TLS3_k127_3195031_2 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.00000000000002383 85.0
TLS3_k127_3196713_0 ADP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 543.0
TLS3_k127_3196713_1 Exporter of polyketide K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 511.0
TLS3_k127_3196713_10 - - - - 0.00000000000000000000000000000000000004065 150.0
TLS3_k127_3196713_11 Roadblock lc7 family protein K07131 - - 0.00000000000000000000000000000000004223 140.0
TLS3_k127_3196713_12 - - - - 0.00000000000001564 85.0
TLS3_k127_3196713_13 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.000000000002061 78.0
TLS3_k127_3196713_2 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 461.0
TLS3_k127_3196713_3 Belongs to the NOS family. Bacterial NOS oxygenase subfamily K00491 - 1.14.14.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 409.0
TLS3_k127_3196713_4 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 357.0
TLS3_k127_3196713_5 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 292.0
TLS3_k127_3196713_6 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001191 269.0
TLS3_k127_3196713_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000006934 161.0
TLS3_k127_3196713_8 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000001729 155.0
TLS3_k127_3196713_9 PIN domain K18828 - - 0.00000000000000000000000000000000000001877 154.0
TLS3_k127_3219256_0 cobaltochelatase CobN subunit K02230 - 6.6.1.2 0.0 1315.0
TLS3_k127_3219256_1 von Willebrand factor type A K03404,K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 516.0
TLS3_k127_3222182_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 426.0
TLS3_k127_3222182_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 357.0
TLS3_k127_3222182_2 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002372 260.0
TLS3_k127_3222182_3 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000001501 124.0
TLS3_k127_3222182_4 Sterol carrier protein domain - - - 0.000000000000000000004805 104.0
TLS3_k127_3222182_5 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000009281 91.0
TLS3_k127_3222182_6 - - - - 0.000000000003289 72.0
TLS3_k127_3234160_0 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002006 253.0
TLS3_k127_3234160_1 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000006763 116.0
TLS3_k127_3234160_2 - - - - 0.0000000001825 68.0
TLS3_k127_3252576_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 578.0
TLS3_k127_3252576_1 RmlD substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009439 432.0
TLS3_k127_3252576_2 Nucleotidyl transferase K00978 - 2.7.7.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 412.0
TLS3_k127_3252576_3 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K00067,K01790 - 1.1.1.133,5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000004841 254.0
TLS3_k127_3252576_4 bifunctional deaminase-reductase domain protein - - - 0.000000000000000000000000000412 118.0
TLS3_k127_3252576_5 Glycosyl transferase, family 2 - - - 0.00000000000000004215 87.0
TLS3_k127_329509_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 372.0
TLS3_k127_329509_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 333.0
TLS3_k127_3314426_0 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 354.0
TLS3_k127_3314426_1 AlkA N-terminal domain K13529 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000001621 279.0
TLS3_k127_3314426_2 spore germination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009941 275.0
TLS3_k127_3314426_3 Domain of unknown function (DUF1707) - - - 0.000000000000000000000000000006128 134.0
TLS3_k127_3320590_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 8.826e-237 758.0
TLS3_k127_3320590_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 454.0
TLS3_k127_3320590_10 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000003151 188.0
TLS3_k127_3320590_11 PFAM Glycosyl transferase, group 1 K08256 GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.345 0.000000000000000000000000000000000000000000942 162.0
TLS3_k127_3320590_12 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000006025 149.0
TLS3_k127_3320590_13 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 0.0000000000000000000000000000000000811 150.0
TLS3_k127_3320590_14 Preprotein translocase K03210 - - 0.00000000000000001009 89.0
TLS3_k127_3320590_15 Protein of unknown function (DUF3048) C-terminal domain - - - 0.00000002171 66.0
TLS3_k127_3320590_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 448.0
TLS3_k127_3320590_3 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 317.0
TLS3_k127_3320590_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001514 284.0
TLS3_k127_3320590_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002211 277.0
TLS3_k127_3320590_6 Metal dependent phosphohydrolases with conserved 'HD' motif. K09163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002326 259.0
TLS3_k127_3320590_7 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000006996 229.0
TLS3_k127_3320590_8 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000002664 231.0
TLS3_k127_3320590_9 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000002297 188.0
TLS3_k127_3332710_0 PFAM monooxygenase FAD-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 434.0
TLS3_k127_3332710_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 425.0
TLS3_k127_3332710_2 Peptidase S15 K06978 - - 0.00000000000000000000000000000000000000000000000000000004432 198.0
TLS3_k127_3332710_3 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000008766 181.0
TLS3_k127_3332710_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000003538 128.0
TLS3_k127_3332710_6 bacterial-type flagellum organization - - - 0.000000003813 67.0
TLS3_k127_3333110_0 Thiamine pyrophosphate enzyme, central domain K03336 - 3.7.1.22 5.001e-224 711.0
TLS3_k127_3333110_1 Transmembrane secretion effector K18215 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009984 583.0
TLS3_k127_3333110_10 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000005395 208.0
TLS3_k127_3333110_11 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000004584 204.0
TLS3_k127_3333110_12 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000002296 201.0
TLS3_k127_3333110_13 transcriptional regulator - - - 0.00000000000000000000000000000000000000000002752 169.0
TLS3_k127_3333110_14 ABC transporter substrate-binding protein K02051 - - 0.000000000000000000000000000000000007498 152.0
TLS3_k127_3333110_15 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02821 - 2.7.1.194 0.000000000000000000000000000004374 125.0
TLS3_k127_3333110_16 Cupin 2, conserved barrel domain protein - - - 0.0000000000000005355 90.0
TLS3_k127_3333110_17 PTS system, Lactose/Cellobiose specific IIB subunit - - - 0.000000000000007394 83.0
TLS3_k127_3333110_2 PTS system ascorbate-specific transporter subunit IIC K03475 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 503.0
TLS3_k127_3333110_3 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 489.0
TLS3_k127_3333110_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 391.0
TLS3_k127_3333110_5 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004511 265.0
TLS3_k127_3333110_6 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009871 245.0
TLS3_k127_3333110_7 triphosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001482 220.0
TLS3_k127_3333110_8 ABC transporter (Permease) K02050 - - 0.0000000000000000000000000000000000000000000000000000000003832 212.0
TLS3_k127_3333110_9 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000001815 222.0
TLS3_k127_3338224_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 596.0
TLS3_k127_3338224_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 466.0
TLS3_k127_3338224_2 cytochrome P-450 K00493 - 1.14.14.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 398.0
TLS3_k127_3338224_3 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002602 264.0
TLS3_k127_3338224_4 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000002072 233.0
TLS3_k127_3338224_5 - - - - 0.000000003502 68.0
TLS3_k127_3338224_6 - - - - 0.00005941 48.0
TLS3_k127_3338224_7 integral membrane protein - - - 0.0008789 47.0
TLS3_k127_3344295_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.0 1134.0
TLS3_k127_3344295_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136 - 4.301e-295 920.0
TLS3_k127_3344295_10 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.00000000000000000000000000000000000000000000000005754 187.0
TLS3_k127_3344295_11 Aldose 1-epimerase K01785 - 5.1.3.3 0.00000000000000000000000000000000000357 149.0
TLS3_k127_3344295_12 GGDEF domain - - - 0.00000000000000000000001961 103.0
TLS3_k127_3344295_13 Protein of unknown function (DUF559) - - - 0.00000000000000000000002404 112.0
TLS3_k127_3344295_14 - - - - 0.0000008439 61.0
TLS3_k127_3344295_2 XdhC Rossmann domain K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 479.0
TLS3_k127_3344295_3 ATPase associated with various cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 422.0
TLS3_k127_3344295_4 Protein containing von Willebrand factor type A (VWA) domain K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 415.0
TLS3_k127_3344295_5 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008302 374.0
TLS3_k127_3344295_6 transferase activity, transferring glycosyl groups K07011,K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 346.0
TLS3_k127_3344295_7 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000008164 260.0
TLS3_k127_3344295_8 Zn-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001829 239.0
TLS3_k127_3344295_9 carbon monoxide dehydrogenase subunit G K09386 - - 0.0000000000000000000000000000000000000000000000000000005715 202.0
TLS3_k127_3352667_0 siderophore-interacting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 402.0
TLS3_k127_3352667_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009433 256.0
TLS3_k127_3352667_10 lactoylglutathione lyase activity K01724 - 4.2.1.96 0.00004383 52.0
TLS3_k127_3352667_11 pyridine nucleotide-disulphide oxidoreductase - - - 0.0007293 49.0
TLS3_k127_3352667_2 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000436 250.0
TLS3_k127_3352667_3 translation initiation factor activity K06996 - - 0.000000000000000000000000000000000000000000002208 171.0
TLS3_k127_3352667_4 AzlC protein - - - 0.0000000000000000000000000000004804 134.0
TLS3_k127_3352667_5 Domain of unknown function (DUF4135) - - - 0.00000000000000000000000000003946 134.0
TLS3_k127_3352667_6 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000005516 126.0
TLS3_k127_3352667_7 Lanthionine synthetase C family protein - - - 0.0000000000000001687 91.0
TLS3_k127_3352667_8 - - - - 0.000000000001952 71.0
TLS3_k127_3358370_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 297.0
TLS3_k127_3358370_1 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000000000004776 229.0
TLS3_k127_3358370_2 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000003908 199.0
TLS3_k127_3366393_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 482.0
TLS3_k127_3366393_1 UDP binding domain K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 367.0
TLS3_k127_3366393_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007143 349.0
TLS3_k127_3367742_0 AMP-binding enzyme K12508 - 6.2.1.34 2.298e-208 668.0
TLS3_k127_3367742_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 452.0
TLS3_k127_3386165_0 FAD linked oxidase domain protein - - - 0.0 1266.0
TLS3_k127_3386165_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000008936 185.0
TLS3_k127_3386165_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000001969 171.0
TLS3_k127_3386165_3 sequence-specific DNA binding - - - 0.000000000000000000002809 108.0
TLS3_k127_3390772_0 transcriptional regulator, SARP family - - - 0.0000000000000000000000000000000000000000000000000001555 202.0
TLS3_k127_3390772_1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000004645 184.0
TLS3_k127_3390772_2 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000312 158.0
TLS3_k127_3390772_3 - - - - 0.00000000000001937 85.0
TLS3_k127_3401897_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 2.671e-218 695.0
TLS3_k127_3401897_1 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 558.0
TLS3_k127_3401897_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000001411 160.0
TLS3_k127_3401897_3 Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000517 153.0
TLS3_k127_3401897_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000001041 141.0
TLS3_k127_3403391_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA - - - 2.636e-262 848.0
TLS3_k127_3424002_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 2.335e-206 655.0
TLS3_k127_3424002_1 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 455.0
TLS3_k127_3424002_2 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 418.0
TLS3_k127_3424002_3 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 417.0
TLS3_k127_3436105_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 466.0
TLS3_k127_3436105_1 Fumarate reductase flavoprotein C-term K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005418 304.0
TLS3_k127_3436105_2 belongs to the nudix hydrolase family - - - 0.000000001043 59.0
TLS3_k127_3436430_0 Ring hydroxylating alpha subunit (catalytic domain) - - - 2.518e-203 640.0
TLS3_k127_3436430_1 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 601.0
TLS3_k127_3436430_2 Ring hydroxylating beta subunit - - - 0.000000000000000000000000000000000000000000000000005762 203.0
TLS3_k127_3436430_3 - - - - 0.000000000000000000000000000000002202 139.0
TLS3_k127_3436430_4 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000002007 128.0
TLS3_k127_3436430_5 - - - - 0.00000000000000000000005169 101.0
TLS3_k127_343875_0 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 - 1.13.11.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005942 454.0
TLS3_k127_343875_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 419.0
TLS3_k127_346874_0 Trypsin-like peptidase domain K01173 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008796 623.0
TLS3_k127_346874_1 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000007709 173.0
TLS3_k127_346874_2 Putative cell wall binding repeat 2 - - - 0.00000003591 66.0
TLS3_k127_346874_3 Heat shock protein DnaJ domain protein - - - 0.000000121 62.0
TLS3_k127_346874_4 FMN-dependent dehydrogenase - - - 0.000176 44.0
TLS3_k127_3512897_0 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 567.0
TLS3_k127_3512897_1 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000945 477.0
TLS3_k127_3512897_3 transposase activity - - - 0.0000000005744 73.0
TLS3_k127_35215_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 301.0
TLS3_k127_35215_1 Transport permease protein K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 305.0
TLS3_k127_35215_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000001118 166.0
TLS3_k127_3523635_0 PFAM oxidoreductase, molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 340.0
TLS3_k127_3523635_1 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009483 322.0
TLS3_k127_3523635_2 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 302.0
TLS3_k127_3523635_3 5'-3' exonuclease - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000002861 186.0
TLS3_k127_3523635_4 - - - - 0.000000000000000000002138 99.0
TLS3_k127_3524146_0 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 288.0
TLS3_k127_3524146_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000004803 144.0
TLS3_k127_352932_0 SMART Nucleotide binding protein, PINc K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 364.0
TLS3_k127_352932_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 304.0
TLS3_k127_352932_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000947 283.0
TLS3_k127_352932_3 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000005114 179.0
TLS3_k127_352932_4 FtsX-like permease family K02004 - - 0.0000000000000000000000000000007523 142.0
TLS3_k127_352932_5 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000003745 98.0
TLS3_k127_352932_6 Belongs to the NadC ModD family K00767,K03813 - 2.4.2.19 0.000000002294 58.0
TLS3_k127_3535988_0 FMN-dependent dehydrogenase K00467 - 1.13.12.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 546.0
TLS3_k127_3535988_1 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003583 280.0
TLS3_k127_3535988_2 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000000000000000002318 116.0
TLS3_k127_353907_0 Amino acid permease - - - 3.006e-202 649.0
TLS3_k127_353907_1 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497,K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 515.0
TLS3_k127_353907_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 357.0
TLS3_k127_353907_3 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 317.0
TLS3_k127_353907_4 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000000000000000000003114 245.0
TLS3_k127_353907_5 transferase activity, transferring glycosyl groups K00713,K03280 - 2.4.1.56 0.00000000000000000000000000000000000000000000000000000000003249 232.0
TLS3_k127_353907_6 CBS domain - - - 0.0000000000000000000000000000000000000000000000000002141 188.0
TLS3_k127_353907_7 Domain of unknown function (DUF1905) - - - 0.0000000000000000000000000000000000000000000000000003387 190.0
TLS3_k127_353907_8 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000002664 132.0
TLS3_k127_353907_9 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000005069 97.0
TLS3_k127_3540593_0 ThiF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 424.0
TLS3_k127_3540593_1 - - - - 0.0000000000000000000005279 105.0
TLS3_k127_3540593_2 PFAM O-antigen - - - 0.000000000000000000001763 109.0
TLS3_k127_3540593_3 Required for chromosome condensation and partitioning K03529 - - 0.000009259 59.0
TLS3_k127_3551640_0 Alpha amylase, catalytic domain K01187,K05341,K05343 - 2.4.1.4,3.2.1.1,3.2.1.20,5.4.99.16 2.995e-229 731.0
TLS3_k127_3551640_1 Transcriptional activator domain - - - 1.937e-200 661.0
TLS3_k127_3551640_10 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000004953 140.0
TLS3_k127_3551640_11 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.00000000000000000000000001921 123.0
TLS3_k127_3551640_12 - - - - 0.00000000006742 72.0
TLS3_k127_3551640_13 - - - - 0.000000001181 61.0
TLS3_k127_3551640_14 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0001766 53.0
TLS3_k127_3551640_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 502.0
TLS3_k127_3551640_3 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 427.0
TLS3_k127_3551640_4 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 387.0
TLS3_k127_3551640_5 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001813 277.0
TLS3_k127_3551640_6 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000003844 242.0
TLS3_k127_3551640_8 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000002486 203.0
TLS3_k127_3551640_9 Histidine kinase - - - 0.00000000000000000000000000000000000000006826 167.0
TLS3_k127_3556120_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 1.702e-210 674.0
TLS3_k127_3556120_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 566.0
TLS3_k127_3556120_10 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 311.0
TLS3_k127_3556120_11 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K15580 - - 0.00000000000000000000000000000000000000000000000000000000008808 225.0
TLS3_k127_3556120_12 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000001003 213.0
TLS3_k127_3556120_13 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000001071 129.0
TLS3_k127_3556120_14 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.00000000000000000000000000000199 138.0
TLS3_k127_3556120_15 PFAM Penicillinase repressor - - - 0.0000000000000000000002292 104.0
TLS3_k127_3556120_16 May be required for sporulation K09762 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944 - 0.0000000000000000000006185 109.0
TLS3_k127_3556120_17 Preprotein translocase SecG subunit K03075 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000004765 74.0
TLS3_k127_3556120_18 Peptidase family M48 - - - 0.000000000001981 80.0
TLS3_k127_3556120_2 Peptide ABC transporter substrate-binding protein K02035,K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 563.0
TLS3_k127_3556120_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 507.0
TLS3_k127_3556120_4 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 456.0
TLS3_k127_3556120_5 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000628 460.0
TLS3_k127_3556120_6 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006866 422.0
TLS3_k127_3556120_7 ABC transporter (Permease) K02033,K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 399.0
TLS3_k127_3556120_8 Peptide ABC transporter permease K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007812 362.0
TLS3_k127_3556120_9 Displays ATPase and GTPase activities K06958 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 321.0
TLS3_k127_3571272_0 PFAM amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 421.0
TLS3_k127_3571272_1 PFAM Mg2 transporter protein CorA family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 402.0
TLS3_k127_3573724_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 3.029e-303 952.0
TLS3_k127_3573724_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 329.0
TLS3_k127_3573724_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009192 341.0
TLS3_k127_3573724_3 formate dehydrogenase K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 321.0
TLS3_k127_3573724_4 molybdopterin cofactor binding K00123,K08348 - 1.17.1.9,1.17.5.3 0.0000000000000000000000000000000000000000000000000000004394 199.0
TLS3_k127_3573724_5 protein involved in formate dehydrogenase formation K02380 - - 0.000000000000000000009136 102.0
TLS3_k127_3573724_6 Protein of unknown function (DUF971) K03593 - - 0.00000000008634 68.0
TLS3_k127_3576671_0 Alanine dehydrogenase/PNT, C-terminal domain K00148 - 1.2.1.46 5.053e-229 717.0
TLS3_k127_3576671_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 442.0
TLS3_k127_3576671_2 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 419.0
TLS3_k127_3576671_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 330.0
TLS3_k127_3576671_4 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000001834 216.0
TLS3_k127_3576671_5 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000008844 198.0
TLS3_k127_3576671_6 protein conserved in bacteria K09957 - - 0.0000000000000000000000000000000000000000289 161.0
TLS3_k127_3576671_7 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000003204 97.0
TLS3_k127_3576897_0 Bacterial extracellular solute-binding protein K10117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000786 616.0
TLS3_k127_3576897_1 Cellulase (glycosyl hydrolase family 5) K01218 - 3.2.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 487.0
TLS3_k127_3576897_2 helix_turn _helix lactose operon repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 379.0
TLS3_k127_3576897_3 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001138 291.0
TLS3_k127_3576897_4 Cobalt ABC transporter K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001229 264.0
TLS3_k127_3576897_6 Belongs to the Fur family K03711 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000002948 85.0
TLS3_k127_3581683_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 313.0
TLS3_k127_3581683_1 Required for chromosome condensation and partitioning K03529 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 304.0
TLS3_k127_3581683_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000001473 113.0
TLS3_k127_3590548_0 Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003585 276.0
TLS3_k127_3590548_1 Protein of unknown function (DUF1697) - - - 0.00000000000000000000000002297 121.0
TLS3_k127_3590548_2 Yqey-like protein K09117 - - 0.000000000000000005705 94.0
TLS3_k127_3590548_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000001785 82.0
TLS3_k127_3590548_4 ubiE/COQ5 methyltransferase family - - - 0.000002293 52.0
TLS3_k127_3593123_0 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 599.0
TLS3_k127_3593123_1 PFAM IstB domain protein ATP-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003831 268.0
TLS3_k127_3593123_2 IstB-like ATP binding protein - - - 0.000000000000000000000000000000000000000002607 168.0
TLS3_k127_3602561_0 DNA primase, small subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 484.0
TLS3_k127_3602561_1 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 476.0
TLS3_k127_3602561_2 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000008739 124.0
TLS3_k127_3602561_3 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000764 107.0
TLS3_k127_3602561_4 Major Facilitator Superfamily - - - 0.0000000000000000007068 102.0
TLS3_k127_3602561_5 Protein of unknown function (DUF998) - - - 0.0000000000009912 79.0
TLS3_k127_3602561_6 Protein of unknown function (DUF998) - - - 0.0000002286 63.0
TLS3_k127_3607796_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 3.959e-209 674.0
TLS3_k127_3607796_1 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 600.0
TLS3_k127_3607796_10 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000009851 121.0
TLS3_k127_3607796_11 PFAM membrane protein of uknown function UCP014873 - - - 0.00000000000000000005105 98.0
TLS3_k127_3607796_12 - - - - 0.0000000000000001521 85.0
TLS3_k127_3607796_13 Protein of unknown function (DUF2905) - - - 0.000000000000007783 83.0
TLS3_k127_3607796_14 PFAM CBS domain K07182 - - 0.0000005471 61.0
TLS3_k127_3607796_15 - - - - 0.00001333 57.0
TLS3_k127_3607796_2 cAMP biosynthetic process K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001774 283.0
TLS3_k127_3607796_3 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000002097 179.0
TLS3_k127_3607796_4 - - - - 0.000000000000000000000000000000000000000000004097 182.0
TLS3_k127_3607796_5 Predicted membrane protein (DUF2243) - - - 0.0000000000000000000000000000000000000000001335 165.0
TLS3_k127_3607796_6 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000000299 163.0
TLS3_k127_3607796_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000000001365 155.0
TLS3_k127_3607796_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000002132 165.0
TLS3_k127_3607796_9 TfoX N-terminal domain - - - 0.00000000000000000000000000000000003698 138.0
TLS3_k127_3611131_0 Cellulase N-terminal ig-like domain K01179 - 3.2.1.4 0.0 1044.0
TLS3_k127_3611131_1 PhoD-like phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 520.0
TLS3_k127_3611131_2 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 442.0
TLS3_k127_3611131_3 Elongation factor G C-terminus K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 417.0
TLS3_k127_3611131_4 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000518 242.0
TLS3_k127_3620111_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 512.0
TLS3_k127_3620111_1 oxidoreductase activity, acting on CH-OH group of donors K13237 - 1.3.1.34 0.000000001607 62.0
TLS3_k127_3626968_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 423.0
TLS3_k127_3626968_1 Beta propeller domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000344 274.0
TLS3_k127_3626968_2 SMART alpha amylase, catalytic sub domain K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000006043 258.0
TLS3_k127_3631804_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 304.0
TLS3_k127_3631804_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 295.0
TLS3_k127_3631804_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003367 258.0
TLS3_k127_3631804_3 Phospholipase_D-nuclease N-terminal - - - 0.000000000000001145 84.0
TLS3_k127_3631804_4 Protein of unknown function (DUF541) K09807 - - 0.000003821 57.0
TLS3_k127_3644424_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001294 290.0
TLS3_k127_3668433_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 327.0
TLS3_k127_3668433_1 Glycosyl transferases group 1 - - - 0.00000000000000000000002032 111.0
TLS3_k127_3683901_0 Superfamily I DNA and RNA helicases and helicase subunits - - - 5.983e-213 690.0
TLS3_k127_3711350_0 ATP synthase alpha/beta family, nucleotide-binding domain K02412 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 406.0
TLS3_k127_3711350_1 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001855 270.0
TLS3_k127_3711350_10 Flagella basal body rod protein K02387 - - 0.0000000000000005187 82.0
TLS3_k127_3711350_11 Flagellar hook-basal body complex protein FliE K02408 - - 0.00000000004992 67.0
TLS3_k127_3711350_2 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006228 270.0
TLS3_k127_3711350_3 The M ring may be actively involved in energy transduction K02409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001514 266.0
TLS3_k127_3711350_4 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 GO:0001539,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006928,GO:0006935,GO:0006996,GO:0008150,GO:0009288,GO:0009425,GO:0009605,GO:0009987,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0040011,GO:0042221,GO:0042330,GO:0042802,GO:0042803,GO:0042995,GO:0043226,GO:0043228,GO:0044085,GO:0044403,GO:0044419,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0044780,GO:0044781,GO:0046982,GO:0046983,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243,GO:0070925,GO:0071840,GO:0071944,GO:0071973,GO:0071978,GO:0097588 - 0.00000000000000000000000000000000000000000000000000000004633 209.0
TLS3_k127_3711350_5 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.00000000000000000000000000000002757 142.0
TLS3_k127_3711350_6 Glycosyl transferase family 2 - - - 0.000000000000000000000000000002943 140.0
TLS3_k127_3711350_7 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000008754 125.0
TLS3_k127_3711350_8 Flagellar basal body rod FlgEFG protein C-terminal K02388 - - 0.0000000000000000000001302 107.0
TLS3_k127_3711350_9 flagellar protein FliS K02422 - - 0.000000000000000000003672 100.0
TLS3_k127_3717626_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 4.688e-232 736.0
TLS3_k127_3717626_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000818 175.0
TLS3_k127_3717626_2 - - - - 0.00000000000000000000000000000000000000001398 168.0
TLS3_k127_3717626_3 Peptidase family M23 - - - 0.00000000000000000000000000000000003648 144.0
TLS3_k127_3717626_4 NAD-dependent epimerase dehydratase - - - 0.00000000002077 66.0
TLS3_k127_3720579_0 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 480.0
TLS3_k127_3720579_1 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001644 255.0
TLS3_k127_3722450_0 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 590.0
TLS3_k127_3722450_1 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 490.0
TLS3_k127_3722450_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 328.0
TLS3_k127_3722450_3 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006431 290.0
TLS3_k127_3722450_4 LacI family K02529 - - 0.000000000000000000000000000000000000001097 163.0
TLS3_k127_3722450_5 DNA polymerase III, beta - - - 0.00000000000000000000000000000000007499 142.0
TLS3_k127_3722450_6 mannose-ethanolamine phosphotransferase activity - - - 0.000000000000000000000000000000001767 151.0
TLS3_k127_3723020_0 Required for chromosome condensation and partitioning K03529 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 394.0
TLS3_k127_3723020_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000004933 243.0
TLS3_k127_3723020_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000002252 231.0
TLS3_k127_3723020_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000003747 206.0
TLS3_k127_3723020_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000002125 140.0
TLS3_k127_3723020_5 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000008927 131.0
TLS3_k127_3723020_6 metal-binding protein K07040 GO:0008150,GO:0040007 - 0.000000000000000000000000000000528 132.0
TLS3_k127_3723020_7 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000002808 130.0
TLS3_k127_3723020_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.00000000000000000000002479 111.0
TLS3_k127_3723020_9 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000002151 71.0
TLS3_k127_3724930_0 PFAM Glycoside hydrolase, family 38 K01191,K15524 - 3.2.1.170,3.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008199 593.0
TLS3_k127_3724930_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 434.0
TLS3_k127_3724930_2 ATPases associated with a variety of cellular activities K10112 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015169,GO:0015399,GO:0015405,GO:0015430,GO:0015605,GO:0015711,GO:0015748,GO:0015794,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098656,GO:1901264,GO:1901505 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000899 420.0
TLS3_k127_3724930_3 ABC-type sugar transport system, periplasmic component K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 444.0
TLS3_k127_3724930_4 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 381.0
TLS3_k127_3724930_5 glycerophosphodiester transmembrane transport K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 310.0
TLS3_k127_3724930_6 PFAM Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 291.0
TLS3_k127_3724930_7 - - - - 0.0000000007086 61.0
TLS3_k127_3724930_8 Helix-turn-helix XRE-family like proteins - - - 0.0007651 51.0
TLS3_k127_3730954_0 Belongs to the glycosyl hydrolase 28 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 583.0
TLS3_k127_3730954_1 trisaccharide binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 527.0
TLS3_k127_3730954_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 458.0
TLS3_k127_3730954_3 Flavin-binding monooxygenase-like K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 431.0
TLS3_k127_3730954_4 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K00481 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0018131,GO:0019438,GO:0030312,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0046872,GO:0046914,GO:0052837,GO:0052838,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.14.13.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 388.0
TLS3_k127_3730954_5 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 312.0
TLS3_k127_3730954_6 B12 binding domain K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000483 257.0
TLS3_k127_3730954_7 Domain of unknown function (DUF4397) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002347 249.0
TLS3_k127_3730954_8 light absorption - - - 0.0002282 50.0
TLS3_k127_3731520_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 0.0 1023.0
TLS3_k127_3731520_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 8.24e-301 935.0
TLS3_k127_3731520_10 Putative NAD(P)-binding K03499 - - 0.00000000000000000000000000000000000000000000000000000000000001178 223.0
TLS3_k127_3731520_11 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000007181 212.0
TLS3_k127_3731520_12 TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000000000000000004104 211.0
TLS3_k127_3731520_13 - - - - 0.00000000000000000000000000000000000000000000000000005887 195.0
TLS3_k127_3731520_14 cyclic nucleotide binding - - - 0.0000000000000000000000000000000000000000000000000001844 206.0
TLS3_k127_3731520_15 - - - - 0.0000000000000000000000000003247 121.0
TLS3_k127_3731520_16 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000004087 111.0
TLS3_k127_3731520_17 Domain of unknown function (DUF1876) - - - 0.00000000000000000000002972 102.0
TLS3_k127_3731520_18 Cupin 2 conserved barrel domain protein - - - 0.0000000000000000002596 99.0
TLS3_k127_3731520_19 Belongs to the small heat shock protein (HSP20) family K13993 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - 0.00003133 51.0
TLS3_k127_3731520_2 His Kinase A (phosphoacceptor) domain - - - 6.426e-243 780.0
TLS3_k127_3731520_3 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 471.0
TLS3_k127_3731520_4 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 383.0
TLS3_k127_3731520_5 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 369.0
TLS3_k127_3731520_6 response regulator, receiver K02483,K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 295.0
TLS3_k127_3731520_7 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000001798 252.0
TLS3_k127_3731520_8 Transcriptional regulator, MarR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003792 238.0
TLS3_k127_3731520_9 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000009472 239.0
TLS3_k127_3735075_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 523.0
TLS3_k127_3735075_1 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008261 330.0
TLS3_k127_3735075_2 Domain related to MnhB subunit of Na+/H+ antiporter K05565,K14086 - - 0.0000000000000000000000000000000000000000000000001144 188.0
TLS3_k127_3735075_3 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.00000000000000000000000000000000002352 147.0
TLS3_k127_3735075_4 Multisubunit Na H antiporter MnhC subunit K05567 - - 0.000000000000000000005414 106.0
TLS3_k127_3735075_5 cation proton antiporter K05571 - - 0.00000000000000000009581 98.0
TLS3_k127_3735075_6 Na H antiporter K05565,K14086 - - 0.000000000000000003107 98.0
TLS3_k127_3735075_7 Na+/H+ ion antiporter subunit K05569 - - 0.0000000000000003578 83.0
TLS3_k127_3735075_8 Multisubunit Na H antiporter, MnhF subunit K05570 - - 0.000003869 56.0
TLS3_k127_3737385_0 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000191 170.0
TLS3_k127_3737385_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000001967 152.0
TLS3_k127_3737385_2 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000003551 127.0
TLS3_k127_3739016_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 327.0
TLS3_k127_3739016_1 von Willebrand factor type A K03404,K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003666 275.0
TLS3_k127_3739016_2 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009111 280.0
TLS3_k127_3743440_0 PFAM Glycoside hydrolase, family 38 K01191,K15524 - 3.2.1.170,3.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 383.0
TLS3_k127_3743440_1 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000000000000000005026 223.0
TLS3_k127_3765368_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 478.0
TLS3_k127_3765368_1 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 423.0
TLS3_k127_3765368_2 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 360.0
TLS3_k127_3765368_3 AMP-forming long-chain acyl-CoA synthetase K01897 - 6.2.1.3 0.000000000000000000000004638 107.0
TLS3_k127_3768091_0 Histidine kinase K07642 - 2.7.13.3 0.00000000002111 76.0
TLS3_k127_3777651_0 cellulose binding - - - 0.0 1143.0
TLS3_k127_3789977_0 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 353.0
TLS3_k127_3789977_1 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 333.0
TLS3_k127_3789977_2 Bacterial periplasmic substrate-binding proteins K10005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000238 288.0
TLS3_k127_3789977_3 - - - - 0.00000000000000000000000000000000000000000000000002241 190.0
TLS3_k127_3796715_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 366.0
TLS3_k127_3796715_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001017 278.0
TLS3_k127_3796715_10 - - - - 0.00000146 60.0
TLS3_k127_3796715_2 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000004944 248.0
TLS3_k127_3796715_3 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000002575 188.0
TLS3_k127_3796715_4 O-methyltransferase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000004585 187.0
TLS3_k127_3796715_5 Protein of unknown function (DUF3151) - - - 0.00000000000000000000000000000000000002634 151.0
TLS3_k127_3796715_6 signal transduction histidine kinase - - - 0.000000000000000000000000001056 127.0
TLS3_k127_3796715_7 Thioesterase superfamily protein - - - 0.000000000000000000000000002698 118.0
TLS3_k127_3796715_8 Ferredoxin - - - 0.000000000003314 78.0
TLS3_k127_3796715_9 PFAM Cupin 2 conserved barrel domain protein - - - 0.000000000006545 70.0
TLS3_k127_3798037_0 Glycosyl hydrolase family 65 central catalytic domain protein K00691,K05342 - 2.4.1.64,2.4.1.8 1.189e-299 940.0
TLS3_k127_3798037_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 330.0
TLS3_k127_3798037_2 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009107 253.0
TLS3_k127_3798037_3 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000002894 123.0
TLS3_k127_3814828_0 FAD binding domain K07077 - - 1.227e-240 754.0
TLS3_k127_3814828_1 PFAM FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 397.0
TLS3_k127_3814828_2 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 392.0
TLS3_k127_3814828_3 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 307.0
TLS3_k127_3814828_4 Bacterial transcriptional repressor C-terminal - - - 0.0000000000000000000000000000000005617 138.0
TLS3_k127_3825884_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 539.0
TLS3_k127_3825884_1 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 473.0
TLS3_k127_3825884_10 DoxX-like family - - - 0.00000000000000000000000000000000000000000000000002407 184.0
TLS3_k127_3825884_11 xyloglucan:xyloglucosyl transferase activity K16559 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000005017 155.0
TLS3_k127_3825884_12 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000001946 123.0
TLS3_k127_3825884_13 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000002594 81.0
TLS3_k127_3825884_2 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 428.0
TLS3_k127_3825884_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 414.0
TLS3_k127_3825884_4 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 408.0
TLS3_k127_3825884_5 PFAM Bacterial regulatory protein, arsR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005087 281.0
TLS3_k127_3825884_6 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001744 267.0
TLS3_k127_3825884_7 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002348 263.0
TLS3_k127_3825884_8 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000001215 220.0
TLS3_k127_3825884_9 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000003538 214.0
TLS3_k127_3837304_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 554.0
TLS3_k127_3837304_1 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000007504 151.0
TLS3_k127_3838040_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 520.0
TLS3_k127_3838040_1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 356.0
TLS3_k127_3838040_2 spheroidene monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000002284 219.0
TLS3_k127_3846711_0 Protein of unknown function (DUF692) K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 423.0
TLS3_k127_3846711_1 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 346.0
TLS3_k127_3846711_2 Trypsin-like serine protease - - - 0.000000000000000000000000000000000000000000000000001759 207.0
TLS3_k127_3846711_3 phenylacetate-CoA ligase activity - - - 0.0000000000000000000000000000000000000000001173 173.0
TLS3_k127_3846711_4 Trypsin-like peptidase domain - - - 0.00000000000000000000000000001791 132.0
TLS3_k127_3846711_5 Belongs to the peptidase S1B family K01183 - 3.2.1.14 0.0000000000000000005114 103.0
TLS3_k127_3846711_6 - - - - 0.00000000346 61.0
TLS3_k127_3846711_7 Carboxypeptidase regulatory-like domain - - - 0.000000548 58.0
TLS3_k127_3859910_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 6.843e-321 994.0
TLS3_k127_3859910_1 Dehydrogenase K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 374.0
TLS3_k127_3859910_2 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002017 278.0
TLS3_k127_3861604_0 alkaline phosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 566.0
TLS3_k127_3861604_1 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.0000000000000000000005945 99.0
TLS3_k127_3864564_0 Type II/IV secretion system protein K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 596.0
TLS3_k127_3864564_1 Pilus assembly protein K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 320.0
TLS3_k127_3864564_10 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000008124 91.0
TLS3_k127_3864564_11 TadE-like protein - - - 0.0001663 49.0
TLS3_k127_3864564_2 Type ii secretion system K12510 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002301 280.0
TLS3_k127_3864564_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000003144 256.0
TLS3_k127_3864564_4 Type ii secretion system K12511 - - 0.00000000000000000000000000000000000000000000000000000000000005974 230.0
TLS3_k127_3864564_5 PFAM Cell envelope-related transcriptional attenuator - - - 0.000000000000000000000000000000000000000000000000000004878 206.0
TLS3_k127_3864564_6 - - - - 0.0000000000000000000000000000003312 140.0
TLS3_k127_3864564_7 Pilus assembly protein K02279 - - 0.0000000000000000000000000000009727 130.0
TLS3_k127_3864564_8 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000001216 124.0
TLS3_k127_3864564_9 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000005386 108.0
TLS3_k127_386490_0 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 507.0
TLS3_k127_386490_1 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009233 467.0
TLS3_k127_386490_10 rRNA binding K02890,K02899,K04074 - - 0.000000000000000000000001321 113.0
TLS3_k127_386490_2 Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008979 312.0
TLS3_k127_386490_3 WYL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008906 249.0
TLS3_k127_386490_4 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000007257 256.0
TLS3_k127_386490_5 Dehydrogenase K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000002594 230.0
TLS3_k127_386490_6 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000000000000000000000000002047 216.0
TLS3_k127_386490_7 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000004567 213.0
TLS3_k127_386490_8 MDMPI C-terminal domain - - - 0.00000000000000000000000000000003628 143.0
TLS3_k127_386490_9 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000567 123.0
TLS3_k127_3865929_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000001706 172.0
TLS3_k127_3865929_1 mitochondrial respiratory chain complex IV assembly K14998 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 - 0.00000000000000000000000000006576 122.0
TLS3_k127_3865929_2 - - - - 0.000000000000000000000001588 116.0
TLS3_k127_3865929_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000003951 64.0
TLS3_k127_3883727_0 MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 320.0
TLS3_k127_3883727_1 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001223 266.0
TLS3_k127_3883727_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002473 257.0
TLS3_k127_3883727_3 RF-1 domain K15034 - - 0.0000000000000000000000000007236 118.0
TLS3_k127_3897983_0 Diguanylate cyclase - - - 1.021e-213 691.0
TLS3_k127_3897983_1 PFAM AP endonuclease family 2 C terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 414.0
TLS3_k127_3897983_2 Protein involved in cellulose biosynthesis - - - 0.00000000000000000000000000000000000000000000000004096 193.0
TLS3_k127_3897983_3 Protein involved in cellulose biosynthesis - - - 0.0000000000000000000000000000000000000000000000001769 195.0
TLS3_k127_3897983_4 Type IV secretory pathway, VirB4 - - - 0.00000000000000000000000000000000000000000000007679 180.0
TLS3_k127_3897983_5 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000000000000000000000002457 160.0
TLS3_k127_3897983_6 Signal peptidase (SPase) II - - - 0.00000000000000000000000000000001987 135.0
TLS3_k127_3897983_7 Lysin motif - - - 0.000000000000000242 94.0
TLS3_k127_3897983_8 ftsk spoiiie K03466 - - 0.0000000008485 72.0
TLS3_k127_3899224_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 310.0
TLS3_k127_3899224_1 Glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 308.0
TLS3_k127_3899224_2 ATPases associated with a variety of cellular activities K09693 - 3.6.3.40 0.000000000000000000000000000000000000000000000000000000000000000001849 237.0
TLS3_k127_3899224_3 ABC-2 type transporter K09692 - - 0.000000000000000000000000000000000000000000000000000001292 204.0
TLS3_k127_3899224_4 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000000000000000000000005962 152.0
TLS3_k127_3899224_5 Stealth protein CR2, conserved region 2 - - - 0.00000001863 64.0
TLS3_k127_3905778_0 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 1.655e-235 736.0
TLS3_k127_3905778_1 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 503.0
TLS3_k127_3905778_2 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006727 438.0
TLS3_k127_3905778_3 Catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone K00382 GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 435.0
TLS3_k127_3905778_4 cytochrome c oxidase K02351,K02862 - - 0.00000000000000000000000000000000000000001383 168.0
TLS3_k127_3905778_5 SCO1/SenC K07152 - - 0.00000000000000000000000001069 121.0
TLS3_k127_3918597_0 Sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 534.0
TLS3_k127_3918597_1 Sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 518.0
TLS3_k127_3918597_2 COG COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms Transcription - - - 0.0000000000000000000000000000000000001336 154.0
TLS3_k127_3918597_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07638 - 2.7.13.3 0.00004872 46.0
TLS3_k127_3922797_0 PFAM Acetamidase Formamidase K01455 - 3.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 444.0
TLS3_k127_3922797_1 TIGRFAM cysteine desulfurase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 349.0
TLS3_k127_3922797_2 Amb_all K01728 - 4.2.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 325.0
TLS3_k127_3922797_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 294.0
TLS3_k127_3922797_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002012 263.0
TLS3_k127_3922797_5 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009157 260.0
TLS3_k127_3922797_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000004777 210.0
TLS3_k127_3922797_7 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000004136 177.0
TLS3_k127_3922797_8 - - - - 0.0000000000726 74.0
TLS3_k127_3929365_0 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 374.0
TLS3_k127_3929365_1 Antibiotic biosynthesis monooxygenase K09932 - - 0.0000000000000000000000000000000000000000000000000000002743 205.0
TLS3_k127_3929365_2 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000003086 190.0
TLS3_k127_3929365_3 Protein of unknown function (DUF3039) - - - 0.000000000000000006831 88.0
TLS3_k127_3932367_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 592.0
TLS3_k127_3932367_1 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000002184 207.0
TLS3_k127_3932367_2 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K13483 - - 0.0000000000000000000000000000001081 143.0
TLS3_k127_3938965_0 helicase superfamily c-terminal domain K05592,K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005571 412.0
TLS3_k127_3938965_1 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009518 265.0
TLS3_k127_3938965_2 Glycosyl transferase 4-like domain K14335 - - 0.00000000000000000000000000000000000000000000000000000000000002463 222.0
TLS3_k127_3938965_3 Sigma-70, region 4 K02405 - - 0.0000000000000000000000000000000000000000000003553 179.0
TLS3_k127_3944304_0 Magnesium transport protein CorA K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 353.0
TLS3_k127_3944304_1 Histidine kinase - - - 0.00000000000000000000000000000000000000002894 176.0
TLS3_k127_3944304_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000006464 113.0
TLS3_k127_3944304_3 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000000000000000000000357 107.0
TLS3_k127_3948310_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 5.24e-250 781.0
TLS3_k127_3948310_1 acyl-CoA dehydrogenase K09456 - - 7.017e-195 626.0
TLS3_k127_3948310_2 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 344.0
TLS3_k127_3948310_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003546 285.0
TLS3_k127_3948310_4 Domain of unknown function (DUF202) K00389 - - 0.000000000000000000000000001834 116.0
TLS3_k127_3949548_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 379.0
TLS3_k127_3949548_1 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008163 306.0
TLS3_k127_3949548_2 Protein of unknown function (DUF418) - - - 0.0000000000000002207 85.0
TLS3_k127_3954957_0 Subtilase family K08651,K14743 - 3.4.21.66 0.0000000000000000000000000000000000000000000000000000000000000000003993 255.0
TLS3_k127_3954957_1 peptidase U61 LD-carboxypeptidase A K01297 - 3.4.17.13 0.0000000000000000000000000000000000000005112 156.0
TLS3_k127_3954957_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000001546 111.0
TLS3_k127_3955467_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 3.275e-316 981.0
TLS3_k127_3955467_1 DNA polymerase III, epsilon subunit K02342 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 413.0
TLS3_k127_3955467_10 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.000000001221 63.0
TLS3_k127_3955467_11 YacP-like NYN domain - - - 0.000000005576 69.0
TLS3_k127_3955467_12 transporter K08195 - - 0.000000007836 68.0
TLS3_k127_3955467_13 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876 - 6.1.1.12 0.000003341 55.0
TLS3_k127_3955467_14 - - - - 0.00001633 56.0
TLS3_k127_3955467_2 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005545 344.0
TLS3_k127_3955467_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009829 331.0
TLS3_k127_3955467_4 Quinone oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 325.0
TLS3_k127_3955467_5 PFAM Glycosyl transferase, group 1 K13668 - 2.4.1.346 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007819 286.0
TLS3_k127_3955467_6 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000001686 243.0
TLS3_k127_3955467_7 Formate/nitrite transporter K21990 - - 0.000000000000000000000000000000000000000000000000000000000000000001656 237.0
TLS3_k127_3955467_8 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000006647 233.0
TLS3_k127_3955467_9 cheY-homologous receiver domain - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000458 75.0
TLS3_k127_3958397_0 Sigma factor PP2C-like phosphatases K04757 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 426.0
TLS3_k127_3958397_1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.000000000000000000000000000000000000000008047 156.0
TLS3_k127_3959051_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 346.0
TLS3_k127_3959051_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 296.0
TLS3_k127_3959051_2 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 297.0
TLS3_k127_3959051_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 GO:0008150,GO:0040007 5.4.99.18 0.00000000000000000000000000000000000000000000000000009323 191.0
TLS3_k127_3959051_4 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000001152 125.0
TLS3_k127_4015181_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 334.0
TLS3_k127_4015181_1 PFAM glycosyl transferase family 39 K00728 - 2.4.1.109 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008582 331.0
TLS3_k127_4015181_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000004678 217.0
TLS3_k127_4015181_3 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000003526 117.0
TLS3_k127_4023380_0 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005987 290.0
TLS3_k127_4023380_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000003012 262.0
TLS3_k127_4023380_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000006052 206.0
TLS3_k127_4023380_3 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000007774 177.0
TLS3_k127_4029343_0 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1230.0
TLS3_k127_4029343_1 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 344.0
TLS3_k127_4029343_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 323.0
TLS3_k127_4029343_3 CoA-binding K09181 - - 0.000000000000000000000000000000000000000001655 162.0
TLS3_k127_4029343_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00001334 57.0
TLS3_k127_4035890_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 306.0
TLS3_k127_4035890_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001765 282.0
TLS3_k127_4035890_2 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000005728 132.0
TLS3_k127_4035890_3 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000003995 98.0
TLS3_k127_4035890_4 lactate/malate dehydrogenase, NAD binding domain K00016,K00024 - 1.1.1.27,1.1.1.37 0.000000000000005897 76.0
TLS3_k127_4044244_0 Elongation factor G, domain IV K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 537.0
TLS3_k127_4044244_1 xyloglucan:xyloglucosyl transferase activity K20846 - 3.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 317.0
TLS3_k127_4044244_2 G5 K21688 - - 0.000000000000000002075 96.0
TLS3_k127_4087593_0 Berberine and berberine like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 495.0
TLS3_k127_4087593_1 YjbR - - - 0.00000000000000000000000000000000000000000000007255 170.0
TLS3_k127_4088373_0 DUF based on E. rectale Gene description (DUF3880) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 393.0
TLS3_k127_4088373_1 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002164 278.0
TLS3_k127_4088373_2 ATPases associated with a variety of cellular activities K09693 - 3.6.3.40 0.000000000000000000000000000000000000000000000000000000000000000000000000004137 265.0
TLS3_k127_4088373_3 ABC-2 type transporter K09692 - - 0.000000000000000000000000000000000000000000000000000009925 203.0
TLS3_k127_4088373_4 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000008163 122.0
TLS3_k127_4088373_5 Glycosyl transferases group 1 - - - 0.0000000000000000000000000008806 121.0
TLS3_k127_4097132_0 Sodium:sulfate symporter transmembrane region K14445 - - 8.678e-238 749.0
TLS3_k127_4097132_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 485.0
TLS3_k127_4097132_2 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 415.0
TLS3_k127_4097132_3 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 385.0
TLS3_k127_4097132_4 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 330.0
TLS3_k127_4097132_5 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005056 253.0
TLS3_k127_4097132_6 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.00000000000000000000000000000000000000000000000000000000001257 217.0
TLS3_k127_4097132_7 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000004137 186.0
TLS3_k127_4101726_0 COGs COG2610 H gluconate symporter and related permease K06156 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 509.0
TLS3_k127_4101726_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002353 276.0
TLS3_k127_4101726_2 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000003226 90.0
TLS3_k127_4106346_0 Belongs to the glycosyl hydrolase 2 family K01195 - 3.2.1.31 4.114e-305 943.0
TLS3_k127_4106346_1 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 8.183e-224 702.0
TLS3_k127_4106346_12 COG3209 Rhs family protein - - - 0.000000000000000000000000009903 127.0
TLS3_k127_4106346_13 self proteolysis - - - 0.000000000000000000000178 113.0
TLS3_k127_4106346_15 cyclic nucleotide-binding K10914 - - 0.0000000001263 76.0
TLS3_k127_4106346_16 Domain of unknown function (DUF2088) - - - 0.000000001638 65.0
TLS3_k127_4106346_17 Cytidylate kinase-like family - - - 0.00000008931 60.0
TLS3_k127_4106346_2 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 594.0
TLS3_k127_4106346_3 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 585.0
TLS3_k127_4106346_4 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 457.0
TLS3_k127_4106346_5 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 409.0
TLS3_k127_4106346_6 PFAM ExsB family protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 391.0
TLS3_k127_4106346_7 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 342.0
TLS3_k127_4106346_8 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001407 277.0
TLS3_k127_4106346_9 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000001705 179.0
TLS3_k127_4110764_0 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000001091 249.0
TLS3_k127_4110764_1 ABC transporter - - - 0.000000000000000000000000000000000000000000000000001695 198.0
TLS3_k127_4110764_2 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000001895 184.0
TLS3_k127_4110764_3 C4-type zinc ribbon domain K07164 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000002379 135.0
TLS3_k127_4110764_4 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.00000000000001158 77.0
TLS3_k127_4121589_0 Phosphotransferase system EIIB cysteine, phosphorylation site K02803,K02804 - 2.7.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 420.0
TLS3_k127_4121589_1 Pts system K02777,K02802 - 2.7.1.193 0.0000000000000000000000000000000000001991 145.0
TLS3_k127_4142118_0 NADP oxidoreductase coenzyme F420-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005772 295.0
TLS3_k127_4142118_1 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000006916 214.0
TLS3_k127_4142118_2 Cupin - - - 0.000000000000000000000002271 109.0
TLS3_k127_4142118_3 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000002185 76.0
TLS3_k127_4144741_0 Superfamily I DNA and RNA helicases and helicase subunits - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 398.0
TLS3_k127_4144741_1 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006098 269.0
TLS3_k127_4144741_2 EamA-like transporter family K03298 - - 0.00000000001255 69.0
TLS3_k127_4155150_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 424.0
TLS3_k127_4155150_1 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 397.0
TLS3_k127_4155150_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 296.0
TLS3_k127_4155150_3 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000665 236.0
TLS3_k127_4155150_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00003488 50.0
TLS3_k127_4171158_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 586.0
TLS3_k127_4171158_1 UbiA prenyltransferase family K14136 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016763,GO:0031224,GO:0031226,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046872,GO:0052636,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.2.45 0.000000000000000000000000000000000000000000000000000000000001025 223.0
TLS3_k127_4171158_2 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000001645 228.0
TLS3_k127_4171158_3 Membrane - - - 0.00000000000000000000000000000000000000000000000000001195 192.0
TLS3_k127_4186148_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 455.0
TLS3_k127_4186148_1 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 348.0
TLS3_k127_4186148_2 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 344.0
TLS3_k127_4186148_3 PFAM Rhomboid family protein - - - 0.000000000000000000000000000000000000000000000000004903 188.0
TLS3_k127_4186148_4 helix_turn_helix ASNC type - - - 0.0000000000000000000000000001421 121.0
TLS3_k127_4192068_0 Belongs to the peptidase M24B family K01271,K01274 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008362 425.0
TLS3_k127_4192068_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 346.0
TLS3_k127_4192068_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01657,K02500 GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 329.0
TLS3_k127_4192068_3 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000006414 248.0
TLS3_k127_4192068_4 Imidazoleglycerol-phosphate dehydratase K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000002876 248.0
TLS3_k127_4192068_5 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814,K01817 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000004694 248.0
TLS3_k127_4192068_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.0000000000000000000000000000000000000000000000000000000001233 223.0
TLS3_k127_4192068_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000001163 184.0
TLS3_k127_4192068_8 Protein of unknown function (DUF4230) - - - 0.0000000000000000000000000000000000000000000002821 182.0
TLS3_k127_4192068_9 Peptidase S16, lon domain protein K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000001849 139.0
TLS3_k127_4222968_0 MviN-like protein K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009374 331.0
TLS3_k127_4222968_1 PFAM Glycosyl transferase, group 1 K19424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 315.0
TLS3_k127_4222968_2 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000402 219.0
TLS3_k127_4222968_3 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000003096 205.0
TLS3_k127_4222968_4 O-Antigen ligase - - - 0.00000000000000000000000000000000000000000000000000005311 202.0
TLS3_k127_4222968_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000003214 183.0
TLS3_k127_4245688_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 347.0
TLS3_k127_4245688_1 ABC transporter K01990,K13926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000775 293.0
TLS3_k127_4245688_2 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000003179 228.0
TLS3_k127_4245688_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000001044 204.0
TLS3_k127_4245688_4 Belongs to the Fur family K03711 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000278 128.0
TLS3_k127_4254945_0 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 467.0
TLS3_k127_4254945_1 S-adenosyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 344.0
TLS3_k127_4254945_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 316.0
TLS3_k127_4254945_3 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000004727 98.0
TLS3_k127_4280213_0 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 334.0
TLS3_k127_4280213_1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000003889 210.0
TLS3_k127_4280213_2 FAD-dependent pyridine nucleotide-disulfide oxidoreductase - - - 0.00000000000000000000000000000000000000000009991 166.0
TLS3_k127_4280213_3 Bacterial PH domain - - - 0.000002563 57.0
TLS3_k127_4280213_4 DNA polymerase A domain K02335 - 2.7.7.7 0.00005007 50.0
TLS3_k127_4281892_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 448.0
TLS3_k127_4281892_1 Glycosyl Transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000013 267.0
TLS3_k127_4281892_2 Sigma 54 modulation/S30EA ribosomal protein C terminus - - - 0.0000000000007903 74.0
TLS3_k127_4291043_0 Polysaccharide biosynthesis protein K03328,K16695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006774 351.0
TLS3_k127_4291043_1 Belongs to the glycosyl hydrolase 32 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 309.0
TLS3_k127_4291043_2 transferase activity, transferring glycosyl groups K00754,K13684 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008378,GO:0008610,GO:0008653,GO:0008921,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035250,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002945 282.0
TLS3_k127_4291043_3 Right handed beta helix region - - - 0.0000000000000000000000000000000000000000000000000000000001594 233.0
TLS3_k127_4291043_4 O-Antigen ligase - - - 0.0000000000000000000000000005903 131.0
TLS3_k127_429323_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 3.011e-232 727.0
TLS3_k127_429323_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 603.0
TLS3_k127_429323_2 Glycosyl transferases group 1 K16148 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 481.0
TLS3_k127_429323_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 411.0
TLS3_k127_429323_4 TIGRFAM exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 325.0
TLS3_k127_429323_5 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000008773 167.0
TLS3_k127_429323_6 Lycopene cyclase K06443 - 5.5.1.19 0.000000000000000000757 93.0
TLS3_k127_429323_7 Clp amino terminal domain, pathogenicity island component - - - 0.00006614 56.0
TLS3_k127_4295541_0 ABC transporter K06147 - - 0.0000000000000000000000000000000000000000000000000000000000695 218.0
TLS3_k127_4295541_1 Belongs to the UPF0234 family K09767 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000005378 176.0
TLS3_k127_4295541_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000006553 128.0
TLS3_k127_4295541_3 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000009563 120.0
TLS3_k127_4295541_4 membrane K08981 - - 0.0000000000000000000005987 106.0
TLS3_k127_4296571_0 phenylalanyl-tRNA synthetase (beta subunit) K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 581.0
TLS3_k127_4296571_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 496.0
TLS3_k127_4296571_10 Regulates arginine biosynthesis genes K03402 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000004458 128.0
TLS3_k127_4296571_2 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 428.0
TLS3_k127_4296571_3 TIGRFAM acetylornithine and succinylornithine K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 386.0
TLS3_k127_4296571_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 360.0
TLS3_k127_4296571_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 309.0
TLS3_k127_4296571_6 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 306.0
TLS3_k127_4296571_7 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004307 286.0
TLS3_k127_4296571_8 Transmembrane secretion effector K18215 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001542 264.0
TLS3_k127_4296571_9 Semialdehyde dehydrogenase, NAD binding domain K00145 GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000002107 252.0
TLS3_k127_4334663_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 370.0
TLS3_k127_4334663_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 362.0
TLS3_k127_4334663_2 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 312.0
TLS3_k127_4334663_3 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000006281 222.0
TLS3_k127_4334663_4 - - - - 0.0000000000000000000000000000000000000000000006538 172.0
TLS3_k127_4334663_5 - - - - 0.000000000000000002705 91.0
TLS3_k127_4334663_6 dehydrogenase complex catalyzes the overall conversion of - - - 0.000000000000004102 84.0
TLS3_k127_4334663_7 - - - - 0.0000000000002886 75.0
TLS3_k127_4339119_0 STAS domain K17763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 310.0
TLS3_k127_4339119_1 STAS domain - - - 0.0000000000000000000000000000000000000000000000000007297 194.0
TLS3_k127_4339119_2 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17762 - - 0.00000000000000000000000000000000000007935 146.0
TLS3_k127_4339119_3 Sigma factor PP2C-like phosphatases K05518 - 3.1.3.3 0.0000000000000000000005678 98.0
TLS3_k127_4341747_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 508.0
TLS3_k127_4341747_1 helix_turn _helix lactose operon repressor - - - 0.000000000000000000000000000000000000000000000000000001275 217.0
TLS3_k127_4341747_2 Sulfotransferase domain - - - 0.00003822 56.0
TLS3_k127_4341747_3 Planctomycete cytochrome C - - - 0.00008839 55.0
TLS3_k127_4349245_0 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 380.0
TLS3_k127_4349245_1 DNA-binding transcriptional activator of the SARP family - GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006355,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019538,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0080090,GO:0090407,GO:0097159,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001001 267.0
TLS3_k127_4369298_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 1.841e-214 674.0
TLS3_k127_4369298_1 UDP-N-acetylglucosamine 2-epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 323.0
TLS3_k127_4369298_2 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 337.0
TLS3_k127_4370582_0 DEAH box helicase K06877 - - 9.962e-229 732.0
TLS3_k127_4370582_1 Belongs to the anti-sigma-factor antagonist family K04749 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000004472 174.0
TLS3_k127_4370582_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000001297 154.0
TLS3_k127_4370582_3 transcriptional regulator - - - 0.00000000000000000000000000000002167 137.0
TLS3_k127_4370582_4 Cupin 2, conserved barrel domain protein - - - 0.0000000003203 70.0
TLS3_k127_4370582_5 anti-sigma regulatory factor - - - 0.0001502 50.0
TLS3_k127_4391965_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 4.906e-321 1037.0
TLS3_k127_4391965_1 Uncharacterised protein family UPF0047 - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000744 164.0
TLS3_k127_4391965_2 Helix-turn-helix domain K07729 - - 0.000000000000000000000009307 102.0
TLS3_k127_4392766_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000002755 248.0
TLS3_k127_4392766_1 Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol K15520 GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701 2.3.1.189 0.0000000000000000000000000000000000000000000000000000000009378 215.0
TLS3_k127_4392766_2 Transcriptional regulator - - - 0.00000001638 66.0
TLS3_k127_4392766_3 ThiS family - - - 0.0004075 52.0
TLS3_k127_4392766_4 - - - - 0.000729 44.0
TLS3_k127_4419203_0 Domain of unknown function (DUF1794) - - - 0.000000000000000000000000000000000002749 143.0
TLS3_k127_4419203_1 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000001122 111.0
TLS3_k127_4419203_2 - - - - 0.0000002191 57.0
TLS3_k127_4428952_0 Pyridine nucleotide-disulphide oxidoreductase K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 388.0
TLS3_k127_4428952_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 349.0
TLS3_k127_4428952_2 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 292.0
TLS3_k127_4428952_3 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000002123 176.0
TLS3_k127_4428952_4 acetyltransferase - - - 0.0000000000000000000000005155 113.0
TLS3_k127_4433108_0 FAD dependent oxidoreductase K16037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 564.0
TLS3_k127_4433108_1 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 341.0
TLS3_k127_4433108_10 pyridoxamine 5-phosphate - - - 0.00000000000000000000000000000406 124.0
TLS3_k127_4433108_11 - - - - 0.000000004062 66.0
TLS3_k127_4433108_2 Lytic polysaccharide mono-oxygenase, cellulose-degrading K22033 - 1.14.99.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 310.0
TLS3_k127_4433108_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002502 274.0
TLS3_k127_4433108_4 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000193 267.0
TLS3_k127_4433108_5 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000001904 223.0
TLS3_k127_4433108_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000001239 167.0
TLS3_k127_4433108_7 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000001608 156.0
TLS3_k127_4433108_8 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000516 142.0
TLS3_k127_4433108_9 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000006721 133.0
TLS3_k127_4458787_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 414.0
TLS3_k127_4458787_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000001377 150.0
TLS3_k127_4464531_0 Extensin-like protein C-terminus - - - 0.00000000000000000000000000000000000000000001292 170.0
TLS3_k127_4464531_1 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.00001269 55.0
TLS3_k127_4464531_2 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.00001359 58.0
TLS3_k127_4469189_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000003273 258.0
TLS3_k127_4469189_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000001602 189.0
TLS3_k127_4469189_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000001104 147.0
TLS3_k127_4469189_3 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000002696 139.0
TLS3_k127_447870_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000004831 192.0
TLS3_k127_447870_1 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000005671 153.0
TLS3_k127_447870_2 MacB-like periplasmic core domain K02004 - - 0.00000001498 66.0
TLS3_k127_4479434_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 618.0
TLS3_k127_4479434_1 Flagella basal body rod protein K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000366 245.0
TLS3_k127_4479434_10 Bacterial export proteins, family 3 K02420 - - 0.0000000000000000007453 89.0
TLS3_k127_4479434_11 PFAM flagellar FlbD family protein K02385 - - 0.000000008424 66.0
TLS3_k127_4479434_12 Membrane - - - 0.00004667 52.0
TLS3_k127_4479434_13 flagellar K02418,K02419 - - 0.0002462 50.0
TLS3_k127_4479434_14 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.0003281 53.0
TLS3_k127_4479434_2 FliP family K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000004963 247.0
TLS3_k127_4479434_3 MotA/TolQ/ExbB proton channel family K02556 - - 0.0000000000000000000000000000000000000000000000000000000061 207.0
TLS3_k127_4479434_4 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000000000000000000000000000000000000000000000004577 204.0
TLS3_k127_4479434_5 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000000000003022 174.0
TLS3_k127_4479434_6 Flagellar hook capping protein - N-terminal region K02389 - - 0.0000000000000000000004804 100.0
TLS3_k127_4479434_7 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 - - 0.000000000000000000007383 99.0
TLS3_k127_4479434_8 Flagellar motor switch protein FliM K02416 - - 0.0000000000000000001192 101.0
TLS3_k127_4479434_9 Role in flagellar biosynthesis K02421 - - 0.0000000000000000003677 97.0
TLS3_k127_4512068_0 FGGY family of carbohydrate kinases, N-terminal domain K00853 - 2.7.1.16 1.71e-206 663.0
TLS3_k127_4512068_1 Class II Aldolase and Adducin N-terminal domain K03077 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019752,GO:0019852,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:1901575 5.1.3.4 0.000000000000000000000000000000000000000000001794 180.0
TLS3_k127_4515771_0 Sodium:neurotransmitter symporter family K03308 - - 1.92e-196 628.0
TLS3_k127_4515771_1 Capsule synthesis protein K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 353.0
TLS3_k127_4515771_2 TOBE domain K02017,K02018 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 350.0
TLS3_k127_4515771_3 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000001261 181.0
TLS3_k127_4515771_4 Anti-sigma-K factor rskA - - - 0.00000000000000000000006466 108.0
TLS3_k127_4518060_0 COGs COG2274 ABC-type bacteriocin lantibiotic exporter contain an N-terminal double-glycine peptidase domain - - - 5.746e-199 640.0
TLS3_k127_4518060_1 - - - - 0.00000000000000000003198 98.0
TLS3_k127_4518060_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000002251 59.0
TLS3_k127_4519883_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.318e-200 644.0
TLS3_k127_4519883_1 Membrane - - - 0.00000000000000000000000000000000000000000000000003907 205.0
TLS3_k127_4519883_2 PFAM Appr-1-p processing domain protein - - - 0.00000000000000000000000000000242 132.0
TLS3_k127_4520870_0 Elongator protein 3, MiaB family, Radical SAM - - - 1.629e-262 823.0
TLS3_k127_4520870_1 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 463.0
TLS3_k127_4520870_2 Belongs to the SEDS family K05837 - - 0.0000000000000000000000000000000000000000000000000086 186.0
TLS3_k127_4520870_3 protein conserved in bacteria - - - 0.0000000000000000000000000000007038 135.0
TLS3_k127_4531996_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00819 - 2.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 520.0
TLS3_k127_4531996_1 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000000000000000002026 180.0
TLS3_k127_4531996_2 Belongs to the glycosyl hydrolase 26 family - - - 0.0000000000000000000000000000000000000000000000003847 186.0
TLS3_k127_4537628_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 566.0
TLS3_k127_4537628_1 PFAM Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000001666 216.0
TLS3_k127_4537628_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000005697 203.0
TLS3_k127_4537628_3 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000004378 197.0
TLS3_k127_4537628_4 Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.00000000000000000000000000000000000000001465 174.0
TLS3_k127_4542609_0 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000003067 239.0
TLS3_k127_4542609_1 Protein of unknown function (DUF3152) - - - 0.00000000000000000000000000000000000000000003184 177.0
TLS3_k127_4559836_0 formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009897 588.0
TLS3_k127_4559836_1 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 415.0
TLS3_k127_4559836_10 carbon dioxide binding K04653,K04654 - - 0.00000002962 61.0
TLS3_k127_4559836_2 Initiates the rapid degradation of small, acid-soluble proteins during spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 323.0
TLS3_k127_4559836_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000007358 219.0
TLS3_k127_4559836_4 - - - - 0.000000000000000000000000000000000000000000000000000000000006353 224.0
TLS3_k127_4559836_5 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000000000004517 191.0
TLS3_k127_4559836_6 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000000000124 171.0
TLS3_k127_4559836_7 transcriptional regulator K07721 - - 0.0000000000000000000000000000000000001097 144.0
TLS3_k127_4559836_8 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.000000000000000000000000008184 113.0
TLS3_k127_4559836_9 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000000000000001987 108.0
TLS3_k127_4560259_0 Phosphatase - - - 0.00000000000000000000000000000000000000000000000000000009883 203.0
TLS3_k127_4560259_1 Sortase family - - - 0.00000000000000000000000000000000000000000005175 169.0
TLS3_k127_4560259_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000007328 158.0
TLS3_k127_4560259_3 Anti-sigma-K factor rskA - - - 0.0000000000000000000000000002777 126.0
TLS3_k127_4574105_0 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 428.0
TLS3_k127_4574105_1 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 382.0
TLS3_k127_4574105_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 350.0
TLS3_k127_4574105_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 299.0
TLS3_k127_4574105_4 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000006905 239.0
TLS3_k127_4574105_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000006342 201.0
TLS3_k127_4576675_0 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 438.0
TLS3_k127_4576675_1 metal-dependent phosphoesterase, PHP family K07053,K20859 - 3.1.3.97,3.1.4.57 0.0000000000000000000000000000000000000000000000000000000000000000001639 240.0
TLS3_k127_4576675_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000006171 181.0
TLS3_k127_4576675_3 PFAM Glycosyl transferase, group 1 K14335 - - 0.00000000000000000000000000000001389 132.0
TLS3_k127_4576675_4 Belongs to the Nudix hydrolase family - - - 0.000000000000000000002581 107.0
TLS3_k127_4576675_5 histone H2A K63-linked ubiquitination - - - 0.0000000000000009097 85.0
TLS3_k127_4576675_6 helix_turn_helix, Lux Regulon - - - 0.0000000000003054 78.0
TLS3_k127_4621038_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 295.0
TLS3_k127_4621038_1 ABC-type cobalamin Fe3 -siderophore transport system, ATPase component K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000474 291.0
TLS3_k127_462312_0 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 464.0
TLS3_k127_462312_1 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 335.0
TLS3_k127_462312_2 Serine aminopeptidase, S33 - - - 0.000000009949 66.0
TLS3_k127_462312_3 enzyme binding K00567,K07443 - 2.1.1.63 0.00000001266 61.0
TLS3_k127_4624240_0 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 627.0
TLS3_k127_4624240_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0000988,GO:0000990,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000000000000000002808 160.0
TLS3_k127_4624240_2 Secreted repeat of unknown function - - - 0.00000000000000000000000000000000000004201 150.0
TLS3_k127_4624240_3 Putative zinc-finger - - - 0.0000000000000000000001088 110.0
TLS3_k127_4624240_4 - - - - 0.00002103 57.0
TLS3_k127_4632503_0 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 334.0
TLS3_k127_4632503_1 PFAM intradiol ring-cleavage dioxygenase K04098 - 1.13.11.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 329.0
TLS3_k127_4632503_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002198 267.0
TLS3_k127_4632503_3 ABC-type nitrate sulfonate bicarbonate transport system, permease component K15554 - - 0.0000000000000000000000000000000000000000000000000000000000000001239 241.0
TLS3_k127_4632503_4 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.0000000000000000000000000000000000006983 142.0
TLS3_k127_463685_0 Fructosamine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005435 255.0
TLS3_k127_463685_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000381 197.0
TLS3_k127_463685_2 Low molecular weight phosphatase family K01104 - 3.1.3.48 0.0000000000000000000000000000000000001198 147.0
TLS3_k127_463685_3 Glycine cleavage T-protein C-terminal barrel domain K06980 - - 0.0000000000000000000000001855 117.0
TLS3_k127_463685_4 response regulator, receiver K07814 - - 0.00000000000003446 78.0
TLS3_k127_4639308_0 pathogenesis - - - 0.0000000000006144 80.0
TLS3_k127_4639308_1 Domain of unknown function (DUF4129) - - - 0.0000002274 63.0
TLS3_k127_4639308_2 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.0005401 43.0
TLS3_k127_465718_0 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000001537 228.0
TLS3_k127_465718_1 Periplasmic binding protein LacI transcriptional regulator - - - 0.0000000000000000000000000000000000002388 142.0
TLS3_k127_4660676_0 Domain of unknown function (DUF4162) K18232 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 521.0
TLS3_k127_4660676_1 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 434.0
TLS3_k127_4660676_10 cell wall organization K18197 - 4.2.2.23 0.0000005419 54.0
TLS3_k127_4660676_11 Phage integrase family - - - 0.0000008881 55.0
TLS3_k127_4660676_2 ABC-2 family transporter protein K18233 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 430.0
TLS3_k127_4660676_3 ERCC3/RAD25/XPB C-terminal helicase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002948 287.0
TLS3_k127_4660676_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000008326 235.0
TLS3_k127_4660676_5 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.00000000000000000000000000000000000000000000000000000005688 203.0
TLS3_k127_4660676_6 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000005776 167.0
TLS3_k127_4660676_7 Histidine kinase - - - 0.0000000000000000000000000000000000311 150.0
TLS3_k127_4660676_8 Domain of unknown function (DUF3291) - - - 0.000000000000000000000001299 111.0
TLS3_k127_4660676_9 Belongs to the glycosyl hydrolase family 6 - - - 0.0000000000000000000003841 95.0
TLS3_k127_4663491_0 adenosine deaminase K01488,K18286 GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.4.4,3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 531.0
TLS3_k127_4663491_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 413.0
TLS3_k127_4663491_2 transport, permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 319.0
TLS3_k127_4663491_3 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000002807 218.0
TLS3_k127_4666340_0 Nad-dependent epimerase dehydratase K01784,K21332 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 389.0
TLS3_k127_4666340_1 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008507 387.0
TLS3_k127_4666340_2 dUTPase K01494 GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000361 261.0
TLS3_k127_4666340_3 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000331 263.0
TLS3_k127_4666340_4 Glycosyl hydrolases family 18 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001333 262.0
TLS3_k127_4666340_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000002538 132.0
TLS3_k127_4666340_6 WbqC-like protein family - - - 0.000000000000002903 88.0
TLS3_k127_4667512_0 ATP synthase alpha/beta chain, C terminal domain K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 622.0
TLS3_k127_4667512_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002448 284.0
TLS3_k127_4667512_2 ATP synthase B/B' CF(0) K02109 - - 0.0000000000000000000000000000000000000000000001936 180.0
TLS3_k127_4667512_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000002158 138.0
TLS3_k127_4667512_4 Pentapeptide repeat protein - - - 0.0000000000000000000000000000000004466 144.0
TLS3_k127_4667512_5 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.0000000000000000000000000000002529 128.0
TLS3_k127_4667512_6 F0F1-ATPase subunit K02116 - - 0.0000000000000000000000000002905 120.0
TLS3_k127_4667512_7 N-ATPase, AtpR subunit - - - 0.00000000000001013 79.0
TLS3_k127_4667512_8 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000126 52.0
TLS3_k127_4668124_0 Animal haem peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 562.0
TLS3_k127_4668124_1 Stealth protein CR2, conserved region 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 369.0
TLS3_k127_4668124_2 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 327.0
TLS3_k127_4668124_3 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002008 255.0
TLS3_k127_4668124_4 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000003515 169.0
TLS3_k127_4668124_5 KR domain - - - 0.0000000000000000000000000001894 126.0
TLS3_k127_4687641_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 570.0
TLS3_k127_4703188_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000001218 234.0
TLS3_k127_4704272_0 HypF finger K04656 - - 3.245e-296 929.0
TLS3_k127_4704272_1 Small subunit K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000005264 235.0
TLS3_k127_4723640_0 Type II secretion system (T2SS), protein F K12510 - - 0.00000000000000003 93.0
TLS3_k127_4723640_1 PFAM Type II secretion system F domain K12511 - - 0.0000000000000001319 91.0
TLS3_k127_4727120_0 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 286.0
TLS3_k127_4727120_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001115 278.0
TLS3_k127_4727120_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001165 243.0
TLS3_k127_4727120_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000003025 214.0
TLS3_k127_4727120_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000006695 198.0
TLS3_k127_4727120_5 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000002362 141.0
TLS3_k127_4727120_6 - - - - 0.00000000001862 74.0
TLS3_k127_4738081_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 4.737e-205 658.0
TLS3_k127_4738081_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0008150,GO:0040007 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 462.0
TLS3_k127_4738081_10 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.0000000000000000000000000000000000000000001698 177.0
TLS3_k127_4738081_11 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000001786 160.0
TLS3_k127_4738081_12 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997,K06925 - 2.7.8.7 0.000000000000000000001148 103.0
TLS3_k127_4738081_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 404.0
TLS3_k127_4738081_3 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016773,GO:0043743,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 315.0
TLS3_k127_4738081_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000003591 239.0
TLS3_k127_4738081_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000001619 235.0
TLS3_k127_4738081_6 F420-dependent oxidoreductase K12234 GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000002867 224.0
TLS3_k127_4738081_7 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002069 204.0
TLS3_k127_4738081_8 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000007712 198.0
TLS3_k127_4738081_9 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000002438 186.0
TLS3_k127_4759138_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 433.0
TLS3_k127_4759138_1 AIR synthase related protein, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000001281 224.0
TLS3_k127_4759138_2 Domain of unknown function (DUF1918) - GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009628,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.00000000000000008033 84.0
TLS3_k127_4759138_3 Belongs to the thiolase family - - - 0.000000000001202 73.0
TLS3_k127_4759138_4 SAF - - - 0.000001425 59.0
TLS3_k127_4759138_5 recombinase activity - - - 0.000737 48.0
TLS3_k127_4776275_0 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 364.0
TLS3_k127_4776275_1 Cytokinin riboside 5'-monophosphate phosphoribohydrolase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000001035 250.0
TLS3_k127_4776275_2 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000000000000006464 166.0
TLS3_k127_4776275_3 CGNR zinc finger - - - 0.00000000000000000000000000004536 123.0
TLS3_k127_4776275_4 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000002599 63.0
TLS3_k127_4776275_5 - - - - 0.00001612 55.0
TLS3_k127_4777889_0 Stealth protein CR3, conserved region 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005985 376.0
TLS3_k127_4777889_1 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 310.0
TLS3_k127_4777889_2 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000001804 200.0
TLS3_k127_4777889_3 - - - - 0.0000000000000000002568 103.0
TLS3_k127_4783124_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1109.0
TLS3_k127_4783124_1 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 9.416e-286 893.0
TLS3_k127_4783124_10 RibD C-terminal domain - - - 0.0000000008855 61.0
TLS3_k127_4783124_11 Histidine kinase - - - 0.0000007594 58.0
TLS3_k127_4783124_2 ROK family K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 291.0
TLS3_k127_4783124_3 Belongs to the WrbA family K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000006917 264.0
TLS3_k127_4783124_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002312 255.0
TLS3_k127_4783124_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000671 239.0
TLS3_k127_4783124_6 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000000000000007082 130.0
TLS3_k127_4783124_7 - - - - 0.000000000000000000000000000003263 129.0
TLS3_k127_4783124_8 - - - - 0.00000000000000000000000000002969 122.0
TLS3_k127_4783124_9 Heavy-metal-associated domain K07213 - - 0.00000000000000008065 90.0
TLS3_k127_4783432_0 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 450.0
TLS3_k127_4783432_1 phosphatidylinositol kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000002783 244.0
TLS3_k127_4783432_2 Protein of unknown function (DUF3090) - - - 0.00000000000000000000000000002213 124.0
TLS3_k127_4789033_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 390.0
TLS3_k127_4789033_1 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000005639 179.0
TLS3_k127_4789033_2 - - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000004789 85.0
TLS3_k127_4813766_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K16422 - 1.1.3.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 306.0
TLS3_k127_4813766_1 Belongs to the UPF0337 (CsbD) family - - - 0.00001608 50.0
TLS3_k127_4821907_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 3.422e-233 740.0
TLS3_k127_4821907_1 DNA helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 397.0
TLS3_k127_4821907_2 Ricin-type beta-trefoil - - - 0.00000000000000000000000000000000000000000000000000002584 196.0
TLS3_k127_4821907_3 pectate lyase K01051,K01728 - 3.1.1.11,4.2.2.2 0.000000000000000000000000000000000000000008815 156.0
TLS3_k127_4821907_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.00000000000000000000000000000007091 134.0
TLS3_k127_4821907_5 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000001255 74.0
TLS3_k127_4827243_0 Domain of unknown function (DUF4037) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 449.0
TLS3_k127_4827243_1 Periplasmic binding protein LacI transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 343.0
TLS3_k127_4827243_2 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006391 261.0
TLS3_k127_4827243_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000002777 232.0
TLS3_k127_4827243_4 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000000001612 204.0
TLS3_k127_4827243_5 S4 RNA-binding domain K04762 - - 0.000000000000000000000000000000000000000000002727 166.0
TLS3_k127_4827243_6 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000006426 126.0
TLS3_k127_4827243_7 Abortive infection protein K07052 - - 0.000000000000000000000000002273 121.0
TLS3_k127_4830408_0 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 388.0
TLS3_k127_4830408_1 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 349.0
TLS3_k127_4830408_2 Belongs to the carbohydrate kinase PfkB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002891 245.0
TLS3_k127_4830408_3 - - - - 0.0000000000000000000000000001078 122.0
TLS3_k127_4831273_0 glucose sorbosone - - - 1.505e-312 974.0
TLS3_k127_4831273_1 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 1.496e-198 634.0
TLS3_k127_4869366_0 Haloacid dehalogenase-like hydrolase K02566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 374.0
TLS3_k127_4869366_1 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000276 188.0
TLS3_k127_4869366_2 mitochondrial respiratory chain complex IV assembly K14998 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 - 0.000000000039 66.0
TLS3_k127_4893006_0 Putative carbohydrate binding domain K00702 - 2.4.1.20 0.0 1226.0
TLS3_k127_4893006_1 hydrolase activity, acting on ester bonds K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 378.0
TLS3_k127_4893006_2 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009622 319.0
TLS3_k127_4893006_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 309.0
TLS3_k127_4893006_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005111 258.0
TLS3_k127_4893006_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000005779 227.0
TLS3_k127_4893006_6 acid phosphatase activity - - - 0.000000000000000000000000000000000002024 153.0
TLS3_k127_4893006_7 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.0000000005519 71.0
TLS3_k127_4897310_0 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 522.0
TLS3_k127_4897310_1 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 520.0
TLS3_k127_4897310_10 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000002453 132.0
TLS3_k127_4897310_11 Endonuclease Exonuclease Phosphatase - - - 0.00000000677 62.0
TLS3_k127_4897310_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007658 427.0
TLS3_k127_4897310_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 364.0
TLS3_k127_4897310_4 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005805 281.0
TLS3_k127_4897310_5 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000001681 247.0
TLS3_k127_4897310_6 BetI-type transcriptional repressor, C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000003361 211.0
TLS3_k127_4897310_7 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000007696 186.0
TLS3_k127_4897310_8 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000003401 178.0
TLS3_k127_4897310_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000003298 141.0
TLS3_k127_4901155_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 588.0
TLS3_k127_4901155_1 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007187 387.0
TLS3_k127_4901155_2 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000008784 254.0
TLS3_k127_4901155_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000007905 129.0
TLS3_k127_4909102_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 3.321e-218 694.0
TLS3_k127_4909102_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000004137 109.0
TLS3_k127_4910576_0 PFAM carboxyl transferase - - - 1.981e-236 747.0
TLS3_k127_4910576_1 Biotin carboxylase C-terminal domain K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 533.0
TLS3_k127_4910576_2 Biotin-(Acetyl-CoA carboxylase) ligase K03524 - 6.3.4.15 0.000000000000000000000000000000000001091 160.0
TLS3_k127_4910576_3 PFAM blue (type 1) copper domain protein K07243 - - 0.0000000000007645 75.0
TLS3_k127_4913057_0 NAD(P)-binding Rossmann-like domain - - - 8.116e-220 694.0
TLS3_k127_4913057_1 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 609.0
TLS3_k127_4913057_10 GlcNAc-PI de-N-acetylase K22135 - - 0.00000000000000000000000000000000000000000001315 173.0
TLS3_k127_4913057_11 BetI-type transcriptional repressor, C-terminal - - - 0.0000000000000000000000000000000000001413 150.0
TLS3_k127_4913057_12 DoxX K15977 - - 0.0000000000000000000003238 101.0
TLS3_k127_4913057_13 Subtilase family - - - 0.00000001389 67.0
TLS3_k127_4913057_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 553.0
TLS3_k127_4913057_3 CoA binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007122 419.0
TLS3_k127_4913057_4 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 399.0
TLS3_k127_4913057_5 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 396.0
TLS3_k127_4913057_6 Putrescine transport system permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 336.0
TLS3_k127_4913057_7 Binding-protein-dependent transport system inner membrane component K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 331.0
TLS3_k127_4913057_8 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 312.0
TLS3_k127_4913057_9 D-alanyl-D-alanine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000123 187.0
TLS3_k127_4945962_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 530.0
TLS3_k127_4945962_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000001242 192.0
TLS3_k127_4945962_2 KR domain - - - 0.00000000000000000000000000000000000001095 155.0
TLS3_k127_4962427_0 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000001163 185.0
TLS3_k127_4962427_1 heme binding K21471,K21472 - - 0.000000000000000000000000000000004692 134.0
TLS3_k127_4962427_2 - - - - 0.000002092 58.0
TLS3_k127_4970140_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000002955 229.0
TLS3_k127_4970140_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000005673 194.0
TLS3_k127_4970140_2 Cytidylate kinase K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000291 172.0
TLS3_k127_4975155_0 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 546.0
TLS3_k127_4975155_1 Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000000000004175 237.0
TLS3_k127_4975155_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000005109 110.0
TLS3_k127_4975155_3 Belongs to the ArsC family - - - 0.0000000000000000000000001023 112.0
TLS3_k127_4975155_4 Rhomboid family K19225 - 3.4.21.105 0.00000000000000934 87.0
TLS3_k127_4994363_0 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 464.0
TLS3_k127_4994363_1 Proline racemase K01777 - 5.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 347.0
TLS3_k127_4994363_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 348.0
TLS3_k127_4994363_3 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000001973 274.0
TLS3_k127_4994363_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001659 256.0
TLS3_k127_4996386_0 PFAM Fatty acid desaturase, type 2 K03921 - 1.14.19.11,1.14.19.2,1.14.19.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 377.0
TLS3_k127_4996386_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007175 352.0
TLS3_k127_4999618_0 Alpha beta hydrolase K03821 - - 0.000000000000000000000000000000000000000000000000000000001778 215.0
TLS3_k127_4999618_1 Belongs to the CinA family - - - 0.0000000000000000000000000000006932 129.0
TLS3_k127_4999618_2 - K07022,K07089 - - 0.00000000000000000000000003698 109.0
TLS3_k127_5004228_0 Ricin-type beta-trefoil - - - 1.113e-224 709.0
TLS3_k127_5004228_1 Stage II sporulation E family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 474.0
TLS3_k127_5004228_2 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 364.0
TLS3_k127_5004228_3 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003181 253.0
TLS3_k127_5004228_4 antisigma factor binding K04749 - - 0.000000000000000000000000007517 114.0
TLS3_k127_5004228_5 antisigma factor binding K03090,K04749,K06378 - - 0.00000000000000000000000002252 117.0
TLS3_k127_5057948_0 GcpE protein K03526 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 451.0
TLS3_k127_5057948_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 419.0
TLS3_k127_5057948_10 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00001554 55.0
TLS3_k127_5057948_2 Participates in both transcription termination and antitermination K02600 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 376.0
TLS3_k127_5057948_3 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 383.0
TLS3_k127_5057948_4 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 306.0
TLS3_k127_5057948_5 PFAM TrkA-N domain K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000005121 231.0
TLS3_k127_5057948_6 PFAM Peptidase family M50 K11749 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000001218 231.0
TLS3_k127_5057948_7 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000002056 142.0
TLS3_k127_5057948_8 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000001322 82.0
TLS3_k127_5057948_9 Protein of unknown function (DUF448) K07742 - - 0.00000001568 63.0
TLS3_k127_5069091_0 PFAM fumarylacetoacetate (FAA) hydrolase K16164 - 3.7.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 322.0
TLS3_k127_5069091_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000004328 223.0
TLS3_k127_5069091_2 Predicted membrane protein (DUF2157) - - - 0.000000000000000000004741 108.0
TLS3_k127_5079280_0 Histidine kinase K07654 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 304.0
TLS3_k127_5079280_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001904 278.0
TLS3_k127_5079280_2 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000002537 138.0
TLS3_k127_5079280_3 Sporulation and spore germination - - - 0.0000000000000000000000000000008642 138.0
TLS3_k127_5079280_4 Serine threonine protein kinase involved in cell cycle control - - - 0.00000000000000000000001592 103.0
TLS3_k127_5079280_5 Immunoglobulin-like domain of bacterial spore germination - - - 0.00000000000000000000004441 113.0
TLS3_k127_5083325_0 DEAD H associated domain protein K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 500.0
TLS3_k127_5083325_1 Belongs to the FPG family K05522 - 4.2.99.18 0.000000000000000000000000000000000000000000000000005793 189.0
TLS3_k127_5085382_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 572.0
TLS3_k127_5085382_1 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000004258 144.0
TLS3_k127_5085382_2 Probable cobalt transporter subunit (CbtA) - - - 0.00000000000000000003934 94.0
TLS3_k127_511674_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 415.0
TLS3_k127_511674_1 NMT1/THI5 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001201 291.0
TLS3_k127_511674_10 - - - - 0.0006968 44.0
TLS3_k127_511674_2 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001003 286.0
TLS3_k127_511674_3 PFAM Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000003777 251.0
TLS3_k127_511674_4 B3 4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000173 220.0
TLS3_k127_511674_5 phosphoribosyltransferase K07100 - - 0.000000000000000000000000000000000000000000000000000000000007864 214.0
TLS3_k127_511674_6 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000000000000000006089 135.0
TLS3_k127_511674_7 Major facilitator Superfamily - - - 0.0000000000000000000000000004199 130.0
TLS3_k127_511674_8 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000001376 98.0
TLS3_k127_5120702_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 5.883e-255 814.0
TLS3_k127_5120702_1 Receptor family ligand binding region K01999 - - 0.000000000000000000008325 109.0
TLS3_k127_5138864_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 310.0
TLS3_k127_5142491_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008787 332.0
TLS3_k127_5142491_1 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 305.0
TLS3_k127_5142491_2 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 4.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000001647 273.0
TLS3_k127_5142491_3 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000002085 213.0
TLS3_k127_5160892_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 395.0
TLS3_k127_5160892_1 AAA ATPase central domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 357.0
TLS3_k127_5161852_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007531 558.0
TLS3_k127_5161852_1 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 286.0
TLS3_k127_5161852_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001098 252.0
TLS3_k127_5167287_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 374.0
TLS3_k127_5167287_1 HRDC domain K03657 GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097 3.6.4.12 0.00000000000000000000000000000000000000000006258 167.0
TLS3_k127_5167287_2 filamentation induced by cAMP protein Fic - - - 0.000000007441 63.0
TLS3_k127_5173733_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00066 - 1.1.1.132 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 497.0
TLS3_k127_5173733_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004493 274.0
TLS3_k127_5173733_2 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000005653 254.0
TLS3_k127_5173733_3 transferase activity, transferring amino-acyl groups - - - 0.000000000008024 79.0
TLS3_k127_5173808_0 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008448 477.0
TLS3_k127_5173808_1 glutamate--cysteine ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 472.0
TLS3_k127_5173808_2 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 454.0
TLS3_k127_5173808_3 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000005077 162.0
TLS3_k127_5175949_0 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 449.0
TLS3_k127_5175949_1 Ku70 and Ku80 are 70kDa and 80kDa subunits of the Lupus Ku autoantigen K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000694 273.0
TLS3_k127_5175949_2 - - - - 0.00000000000000000000000000000000000000000000003442 188.0
TLS3_k127_5175949_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000002817 140.0
TLS3_k127_5175949_4 glyoxalase III activity - - - 0.00000000000000000000000000000000104 145.0
TLS3_k127_5175949_5 DNA-binding transcription factor activity - - - 0.000000000000000000008748 98.0
TLS3_k127_5182457_0 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 308.0
TLS3_k127_5182457_1 - - - - 0.00000000000000000000000000000000000000000000000000000000001085 219.0
TLS3_k127_5182457_2 Glycosyl transferase WecB/TagA/CpsF family K05946 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000003121 202.0
TLS3_k127_5211124_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 422.0
TLS3_k127_5211124_1 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002018 289.0
TLS3_k127_5211124_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003388 245.0
TLS3_k127_5211124_3 Uncharacterized conserved protein (COG2071) K09166 - - 0.0000000000000000000000000000000000000000000000359 178.0
TLS3_k127_5226351_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 564.0
TLS3_k127_5226351_1 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 549.0
TLS3_k127_5226351_10 Isochorismatase family - - - 0.00000000000000000000146 104.0
TLS3_k127_5226351_11 Thioesterase superfamily K07107 - - 0.000000000000000000002185 103.0
TLS3_k127_5226351_12 Pfam:DUF59 K02612 - - 0.00000000000000005406 94.0
TLS3_k127_5226351_13 Helix-turn-helix XRE-family like proteins - - - 0.00000005927 61.0
TLS3_k127_5226351_15 phenylacetate-CoA oxygenase, PaaJ subunit K02612 - - 0.000008844 51.0
TLS3_k127_5226351_2 phenylacetic acid catabolic K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008497 431.0
TLS3_k127_5226351_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003046 257.0
TLS3_k127_5226351_4 HipA-like C-terminal domain K07154 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000004728 233.0
TLS3_k127_5226351_5 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000001123 197.0
TLS3_k127_5226351_6 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000003559 183.0
TLS3_k127_5226351_7 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000006885 169.0
TLS3_k127_5226351_8 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000792 139.0
TLS3_k127_5226351_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000009084 122.0
TLS3_k127_5236959_0 ABC transporter K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 427.0
TLS3_k127_5236959_1 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003059 277.0
TLS3_k127_5236959_2 Peptidase S24-like K03100 - 3.4.21.89 0.00000000000000000000005395 107.0
TLS3_k127_5243737_0 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000009523 204.0
TLS3_k127_5243737_1 - - - - 0.00000000000000000000000000000000003593 149.0
TLS3_k127_5243737_2 diguanylate cyclase - - - 0.0000000000000000000000000000000009057 149.0
TLS3_k127_5243737_4 Protein conserved in bacteria K09796 - - 0.00002068 48.0
TLS3_k127_5248849_0 fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 432.0
TLS3_k127_5248849_1 FAD dependent oxidoreductase K06954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001926 287.0
TLS3_k127_5280245_0 PFAM deoxyribose-phosphate aldolase phospho-2- dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 556.0
TLS3_k127_5280245_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 379.0
TLS3_k127_5280245_2 Branched-chain amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 311.0
TLS3_k127_5280245_3 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 299.0
TLS3_k127_5280245_4 PFAM Branched-chain amino acid transport protein (AzlD) - - - 0.0000000000000000000000000001342 130.0
TLS3_k127_5280245_5 Domain of unknown function (DUF1707) - - - 0.0000000001037 68.0
TLS3_k127_5280245_6 Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family K00561 - 2.1.1.184 0.000000009502 60.0
TLS3_k127_530320_0 PFAM magnesium chelatase ChlI subunit K07391 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000008064 203.0
TLS3_k127_530320_1 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000002891 109.0
TLS3_k127_530320_2 Protein conserved in bacteria - - - 0.00000000000000000001095 104.0
TLS3_k127_5308599_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1196.0
TLS3_k127_5308599_1 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000000000000000000000000000001138 153.0
TLS3_k127_5308599_2 peptidase U61 LD-carboxypeptidase A K01297 - 3.4.17.13 0.0000000000006943 78.0
TLS3_k127_5327601_0 Enoyl-CoA hydratase/isomerase K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 297.0
TLS3_k127_5327601_1 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007197 245.0
TLS3_k127_5327601_2 aldo keto reductase - - - 0.00000000000000000000000000000000000000001526 169.0
TLS3_k127_5331297_0 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009265 471.0
TLS3_k127_5331297_1 Aminoacyl-tRNA editing domain K03976 - - 0.0000000000000000000000000000000000000000000000000000000000000001072 229.0
TLS3_k127_5331297_2 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000006744 160.0
TLS3_k127_5331297_3 Toxic component of a toxin-antitoxin (TA) module K07171 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - 0.000000000000000000000113 104.0
TLS3_k127_5346077_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 3.475e-227 731.0
TLS3_k127_5346077_1 General secretory system II, protein E domain protein K02652 - - 6.697e-207 661.0
TLS3_k127_5346077_10 Bacterial extracellular solute-binding protein, family 7 K21395 - - 0.00000000000000000000000000002609 129.0
TLS3_k127_5346077_11 type IV pilus modification protein PilV - - - 0.000000000000000000000000001804 128.0
TLS3_k127_5346077_12 Mannose-6-phosphate isomerase - - - 0.000000000000000000000007389 109.0
TLS3_k127_5346077_13 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000004175 93.0
TLS3_k127_5346077_14 Prokaryotic N-terminal methylation motif K02650 - - 0.000000000000000005973 94.0
TLS3_k127_5346077_15 - - - - 0.000000000000001311 91.0
TLS3_k127_5346077_16 DNA binding domain, excisionase family - - - 0.0000000000001472 72.0
TLS3_k127_5346077_17 general secretion pathway protein K02650 - - 0.0000000000004596 79.0
TLS3_k127_5346077_18 Domain of unknown function (DUF4388) - - - 0.00002038 57.0
TLS3_k127_5346077_19 PFAM Fimbrial assembly family protein K02663 - - 0.00006822 54.0
TLS3_k127_5346077_2 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 501.0
TLS3_k127_5346077_20 carbon utilization - - - 0.0001644 53.0
TLS3_k127_5346077_3 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 426.0
TLS3_k127_5346077_4 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 304.0
TLS3_k127_5346077_5 pilus assembly protein PilW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001236 302.0
TLS3_k127_5346077_6 pilus assembly protein PilM K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000013 266.0
TLS3_k127_5346077_7 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000003577 193.0
TLS3_k127_5346077_8 KR domain K00059,K07535 - 1.1.1.100 0.0000000000000000000000000000000000000009747 158.0
TLS3_k127_5346077_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000001476 154.0
TLS3_k127_5355843_0 belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.00000000000000000000000000000000000000000008469 163.0
TLS3_k127_5355843_1 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.0000000000000000000000000000000000004298 152.0
TLS3_k127_5355843_2 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 0.00003051 52.0
TLS3_k127_5360936_0 Cell envelope-related transcriptional attenuator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 381.0
TLS3_k127_5360936_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 321.0
TLS3_k127_5360936_2 Pas domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 325.0
TLS3_k127_5360936_3 Domain of unknown function (DUF1990) - - - 0.0000000000000000000000000000000000000000000000000000000000000256 233.0
TLS3_k127_5360936_4 Domain of unknown function (DUF1990) - - - 0.0000000000000000000000000000000000000000000815 179.0
TLS3_k127_5360936_5 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000002847 145.0
TLS3_k127_5360936_6 - - - - 0.000000000000000000000000000000002813 139.0
TLS3_k127_5360936_7 Domain of unknown function (DUF1905) - - - 0.00000000000000000000000000000002811 134.0
TLS3_k127_5360936_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000005054 79.0
TLS3_k127_5457311_0 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 525.0
TLS3_k127_5461284_0 Aldehyde oxidase and xanthine dehydrogenase K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 554.0
TLS3_k127_5461284_1 dna ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 458.0
TLS3_k127_5461284_2 PFAM Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 325.0
TLS3_k127_5461284_3 YHS domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 294.0
TLS3_k127_5461284_4 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004049 278.0
TLS3_k127_5461284_5 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP) K03707 - 3.5.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000002969 266.0
TLS3_k127_5461284_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000111 240.0
TLS3_k127_5461284_7 Hydrolase - - - 0.00000000000000000000000000000000000001969 156.0
TLS3_k127_5461284_8 Protein of unknown function (DUF559) - - - 0.0000000006595 71.0
TLS3_k127_5470314_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 5.284e-300 956.0
TLS3_k127_5470314_1 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 362.0
TLS3_k127_5470314_2 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 341.0
TLS3_k127_5470314_3 Binding-protein-dependent transport system inner membrane component K10118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 299.0
TLS3_k127_5470314_4 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001591 275.0
TLS3_k127_5470314_5 - - - - 0.0000000000000000000000000000000000000000006527 173.0
TLS3_k127_5470314_6 Histidine kinase - - - 0.000000000000000000000000000000000002234 155.0
TLS3_k127_5470314_7 HTH domain - - - 0.00000000000000000000000000007541 133.0
TLS3_k127_5470314_8 SnoaL-like domain - - - 0.0000000000000000000008817 95.0
TLS3_k127_5470314_9 Histidine kinase - - - 0.0000002402 60.0
TLS3_k127_5470689_0 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 512.0
TLS3_k127_5470689_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 409.0
TLS3_k127_5470689_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 398.0
TLS3_k127_5470689_3 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000002962 188.0
TLS3_k127_5470689_4 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000002942 142.0
TLS3_k127_5470689_5 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000001029 135.0
TLS3_k127_5470689_6 Cell envelope-related transcriptional attenuator domain - - - 0.00000000000000000000000002637 121.0
TLS3_k127_5470689_7 YCII-related domain - - - 0.00000000000000002269 91.0
TLS3_k127_5470689_8 YCII-related domain - - - 0.00000000000000002753 89.0
TLS3_k127_5470689_9 YCII-related domain - - - 0.000000000000001182 82.0
TLS3_k127_5482818_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 495.0
TLS3_k127_5482818_1 PFAM regulatory protein, MerR - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000006612 195.0
TLS3_k127_5482818_2 (FHA) domain - - - 0.000000000000000000000000000000000000000000000000174 181.0
TLS3_k127_5482818_3 PFAM peptidase S11, D-alanyl-D-alanine carboxypeptidase K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000001522 181.0
TLS3_k127_5482818_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000001956 166.0
TLS3_k127_5482818_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000000001044 154.0
TLS3_k127_5511361_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 355.0
TLS3_k127_5511361_1 Protein of unknown function (DUF2786) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004433 251.0
TLS3_k127_5511361_2 - - - - 0.00000001187 66.0
TLS3_k127_5514771_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 460.0
TLS3_k127_5514771_1 extracellular solute-binding K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 388.0
TLS3_k127_5514771_2 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 0.0000000000000000000000000000000000000001156 170.0
TLS3_k127_5516088_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 422.0
TLS3_k127_5516088_1 Lysylphosphatidylglycerol synthase TM region K07027,K20468 - - 0.00000000000000000000000000001357 128.0
TLS3_k127_5516088_2 ABC transporter - - - 0.000000000003739 66.0
TLS3_k127_5519711_0 Peptidase S9 prolyl oligopeptidase active site domain protein K01303 - 3.4.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 551.0
TLS3_k127_5519711_1 aminotransferase class I and II K00812,K10907,K14260,K14261 - 2.6.1.1,2.6.1.2,2.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 518.0
TLS3_k127_5519711_10 Short-chain dehydrogenase reductase sdr K00218 - 1.3.1.33 0.00000000000005421 84.0
TLS3_k127_5519711_11 - - - - 0.00000000007654 67.0
TLS3_k127_5519711_2 50S ribosome-binding GTPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003046 271.0
TLS3_k127_5519711_3 Domain of unknown function (DUF368) K08974 - - 0.000000000000000000000000000000000000000000000000000000000000000000008641 245.0
TLS3_k127_5519711_4 Ferritin-like domain K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000008808 240.0
TLS3_k127_5519711_5 PFAM PEBP family protein K06910,K07032 - - 0.0000000000000000000000000000000000007324 149.0
TLS3_k127_5519711_6 RecB family K07465 - - 0.00000000000000000000000000000007454 139.0
TLS3_k127_5519711_7 ABC transporter - - - 0.00000000000000000000000000007465 126.0
TLS3_k127_5519711_8 PFAM regulatory protein TetR - - - 0.0000000000000000000003361 104.0
TLS3_k127_5519711_9 of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000014 96.0
TLS3_k127_5526534_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 377.0
TLS3_k127_5526534_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000001492 248.0
TLS3_k127_5526534_2 belongs to the sigma-70 factor family, ECF subfamily K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000000001437 98.0
TLS3_k127_5526534_3 COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT K02669 - - 0.0001242 52.0
TLS3_k127_5541022_0 - - - - 0.00000000000000251 80.0
TLS3_k127_5541022_1 gluconolactonase activity - - - 0.00000000000002739 81.0
TLS3_k127_5541690_0 Aldo/keto reductase family K13315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 479.0
TLS3_k127_5541690_1 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 358.0
TLS3_k127_5541690_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 334.0
TLS3_k127_5541690_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 304.0
TLS3_k127_5541690_4 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000001784 69.0
TLS3_k127_5543865_0 type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 514.0
TLS3_k127_5543865_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 413.0
TLS3_k127_5543865_2 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003836 291.0
TLS3_k127_5543865_3 Domain present in PSD-95, Dlg, and ZO-1/2. K08372 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007947 257.0
TLS3_k127_5543865_4 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000001012 80.0
TLS3_k127_5543865_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000168 67.0
TLS3_k127_5548839_0 Luciferase-like monooxygenase - - - 7.558e-209 654.0
TLS3_k127_5548839_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 553.0
TLS3_k127_5548839_2 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 315.0
TLS3_k127_5548839_3 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002736 280.0
TLS3_k127_5548839_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000004578 174.0
TLS3_k127_5612630_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.493e-217 713.0
TLS3_k127_5612630_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 377.0
TLS3_k127_5612630_2 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000125 130.0
TLS3_k127_5612630_3 NmrA-like family - - - 0.0000000000000000002499 91.0
TLS3_k127_5612630_4 PFAM heat shock protein DnaJ domain protein K03686,K05516 - - 0.00000005305 66.0
TLS3_k127_5612630_5 helix_turn _helix lactose operon repressor K02529 - - 0.00009106 46.0
TLS3_k127_5612745_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 571.0
TLS3_k127_5612745_1 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 449.0
TLS3_k127_5612745_2 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 441.0
TLS3_k127_5612745_3 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005768 250.0
TLS3_k127_5612745_4 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000003535 140.0
TLS3_k127_5612745_5 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.000000000000000000003193 109.0
TLS3_k127_5612745_6 Major Facilitator Superfamily - - - 0.000000000000007625 87.0
TLS3_k127_5612745_7 helix_turn _helix lactose operon repressor K02529 - - 0.0004308 46.0
TLS3_k127_561535_0 TIGRFAM nitrite extrusion protein (nitrite facilitator) K02575 GO:0003674,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015112,GO:0015113,GO:0015318,GO:0015698,GO:0015706,GO:0015707,GO:0022857,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0071705,GO:0098656,GO:1902025 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 497.0
TLS3_k127_561535_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372,K02567 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 480.0
TLS3_k127_5623330_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 563.0
TLS3_k127_5623330_1 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 442.0
TLS3_k127_5630353_0 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 390.0
TLS3_k127_5630353_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001005 270.0
TLS3_k127_5630353_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000001163 68.0
TLS3_k127_5633844_0 Right handed beta helix region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003628 268.0
TLS3_k127_5633844_1 Glutathione S-transferase, C-terminal domain K07393 - 1.8.5.7 0.00000000000000000000000000000000000007259 142.0
TLS3_k127_5633844_2 Carboxylesterase family K01066 - - 0.00000000000000000000000000000000005004 151.0
TLS3_k127_5633844_3 FR47-like protein - - - 0.0000000000000000007644 92.0
TLS3_k127_5633844_4 Transcriptional regulator PadR-like family - - - 0.0007338 47.0
TLS3_k127_5647801_0 Tetrapyrrole (Corrin/Porphyrin) Methylases K13541 - 2.1.1.131,3.7.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 573.0
TLS3_k127_5647801_1 Tetrapyrrole (Corrin/Porphyrin) Methylases K00595 - 2.1.1.132 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 362.0
TLS3_k127_5647801_2 Tetrapyrrole (Corrin/Porphyrin) Methylases K05936 - 2.1.1.133,2.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 317.0
TLS3_k127_5647801_3 cobalamin (vitamin B12) biosynthesis CbiX K03795 - 4.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 305.0
TLS3_k127_5647801_4 Tetrapyrrole (Corrin/Porphyrin) Methylases K03394 - 2.1.1.130,2.1.1.151 0.000000000000000000000000000000000000000000000000000000000000000364 235.0
TLS3_k127_5647801_5 Precorrin-8X methylmutase K06042 - 5.4.99.60,5.4.99.61 0.00000000000000000000000000000000000000000000000000000000000008012 224.0
TLS3_k127_5647801_6 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000007121 185.0
TLS3_k127_5647801_7 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000000000001615 102.0
TLS3_k127_5721573_0 Anion-transporting ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 336.0
TLS3_k127_5721573_1 PFAM Anion-transporting ATPase - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000001814 224.0
TLS3_k127_5721573_2 Membrane-bound serine protease (ClpP class) K07403 - - 0.00000000000000000000000000043 130.0
TLS3_k127_5723746_0 cytochrome oxidase assembly K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001161 289.0
TLS3_k127_5723746_1 PFAM Archaeal ATPase K06921 - - 0.00000000000000000000000000000000000000000000000000000961 207.0
TLS3_k127_5723746_2 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01911,K02549 GO:0003674,GO:0003824,GO:0008150,GO:0008756,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0040007 4.2.1.113,6.2.1.26 0.00000000000000000000000000000000000000000000003148 175.0
TLS3_k127_5723746_3 peptidase C60 sortase A and B - - - 0.00000000000000000000000000000000000000009078 161.0
TLS3_k127_5723746_4 Alpha Beta K06889 - - 0.0000000000000000001381 96.0
TLS3_k127_5754378_0 - - - - 0.00000000000000000000000000001359 135.0
TLS3_k127_5754378_1 ATP- GTP-binding protein - - - 0.0000000000000000482 89.0
TLS3_k127_5755847_0 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 452.0
TLS3_k127_5755847_1 PFAM regulatory protein LuxR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008886 390.0
TLS3_k127_5755847_2 Domain of unknown function (DUF427) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 349.0
TLS3_k127_5755847_3 NAD dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000001753 229.0
TLS3_k127_5755847_4 Domain of unknown function (DUF4281) - - - 0.000000000000000002757 89.0
TLS3_k127_5755847_5 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000007402 81.0
TLS3_k127_5763457_0 Superfamily I DNA and RNA helicases and helicase subunits - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008913 265.0
TLS3_k127_5763457_1 Belongs to the thioredoxin family K00384,K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.9 0.0000000000000000000000000000000000000000000000000006569 186.0
TLS3_k127_5763457_2 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000001409 145.0
TLS3_k127_5763457_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000007571 109.0
TLS3_k127_5763457_4 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000002273 105.0
TLS3_k127_5763457_5 amino acid transport - - - 0.00000007518 63.0
TLS3_k127_5763457_6 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0008164 48.0
TLS3_k127_5764201_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000438 243.0
TLS3_k127_5764201_1 AMP binding - - - 0.0000000007844 62.0
TLS3_k127_5768739_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000265 247.0
TLS3_k127_5768739_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000009315 177.0
TLS3_k127_5768739_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000006731 166.0
TLS3_k127_577042_0 Pyrimidine nucleoside phosphorylase C-terminal domain K00756 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 353.0
TLS3_k127_577042_1 Phage integrase, N-terminal SAM-like domain K04763 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 314.0
TLS3_k127_577042_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000003977 182.0
TLS3_k127_577042_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000003722 168.0
TLS3_k127_577042_4 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000002271 156.0
TLS3_k127_577042_5 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000004446 97.0
TLS3_k127_5783191_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 548.0
TLS3_k127_5797389_0 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 584.0
TLS3_k127_5797389_1 PFAM Xylose isomerase domain protein TIM barrel K06605 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 476.0
TLS3_k127_5797389_2 Oxidoreductase family, NAD-binding Rossmann fold K18652 - 1.1.1.361 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 410.0
TLS3_k127_5797389_3 Belongs to the hyi family K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 368.0
TLS3_k127_5797389_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 337.0
TLS3_k127_5797389_5 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 344.0
TLS3_k127_5797389_6 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000004341 221.0
TLS3_k127_5797389_7 Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) K00010 - 1.1.1.18,1.1.1.369 0.0000000000531 63.0
TLS3_k127_5797389_8 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0001663 49.0
TLS3_k127_5802000_0 Phosphotransferase System K02768,K02769,K02770,K02794,K02795 - 2.7.1.191,2.7.1.202 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 606.0
TLS3_k127_5802000_1 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003575 271.0
TLS3_k127_5802000_2 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001127 261.0
TLS3_k127_5821674_0 belongs to the CobB CobQ family K13788 - 2.3.1.8 3.474e-236 754.0
TLS3_k127_5821674_1 alcohol dehydrogenase - - - 1.259e-209 662.0
TLS3_k127_5821674_10 Belongs to the UPF0336 family - - - 0.00000000000000000192 90.0
TLS3_k127_5821674_2 beta-lactamase domain protein K13075 - 3.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 464.0
TLS3_k127_5821674_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008117 438.0
TLS3_k127_5821674_4 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 307.0
TLS3_k127_5821674_5 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000007681 220.0
TLS3_k127_5821674_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000005688 203.0
TLS3_k127_5821674_7 Regulatory protein, FmdB family - - - 0.00000000000000000000000000000000000000000000005791 175.0
TLS3_k127_5821674_8 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000002525 169.0
TLS3_k127_5821674_9 PFAM MaoC domain protein dehydratase - - - 0.0000000000000000000256 101.0
TLS3_k127_5840727_0 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 409.0
TLS3_k127_5840727_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000002158 232.0
TLS3_k127_5840727_2 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000626 196.0
TLS3_k127_5840727_3 Probable cobalt transporter subunit (CbtB) - - - 0.000000003205 60.0
TLS3_k127_5840727_4 Probable cobalt transporter subunit (CbtA) - - - 0.0000004655 57.0
TLS3_k127_5841970_0 PFAM Aldehyde dehydrogenase K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 466.0
TLS3_k127_5841970_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000001453 267.0
TLS3_k127_5841970_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000006907 183.0
TLS3_k127_5841970_3 Transcriptional regulator - - - 0.000000000000000000000003627 111.0
TLS3_k127_5844646_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 6.585e-203 652.0
TLS3_k127_5844646_1 Pfam UbiA prenyltransferase - - - 0.0000000000000000000000000000000000000000000000000000008642 209.0
TLS3_k127_5844646_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000001694 92.0
TLS3_k127_5874831_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 445.0
TLS3_k127_5874831_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002246 299.0
TLS3_k127_5874831_2 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000009038 235.0
TLS3_k127_5874831_3 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000003193 226.0
TLS3_k127_5874831_4 Exporter of polyketide K01992 - - 0.0000000000000000000000000000000000000000000000000002478 200.0
TLS3_k127_5874831_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000002934 115.0
TLS3_k127_5874831_6 Exporter of polyketide K01992 - - 0.00000000000002526 84.0
TLS3_k127_5881530_0 Belongs to the glycosyl hydrolase 13 family K01200,K01214 - 3.2.1.41,3.2.1.68 0.0 1088.0
TLS3_k127_5881530_1 Animal haem peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006881 599.0
TLS3_k127_5881530_2 Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 415.0
TLS3_k127_5881530_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009547 357.0
TLS3_k127_5881530_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 312.0
TLS3_k127_5881530_5 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007563 226.0
TLS3_k127_5881530_6 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000001128 195.0
TLS3_k127_5881530_7 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000001923 128.0
TLS3_k127_5881530_8 Histidine kinase - - - 0.0000000000000000000000000007647 130.0
TLS3_k127_5881530_9 lactoylglutathione lyase activity - - - 0.000000000000001657 84.0
TLS3_k127_5921149_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 422.0
TLS3_k127_5921149_1 GTP cyclohydrolase II K14652 GO:0005575,GO:0005576,GO:0008150,GO:0040007 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000007497 146.0
TLS3_k127_5921149_2 domain protein associated with RNAses G and E K07586 - - 0.0000000000000000002611 94.0
TLS3_k127_5921149_3 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.0000000000000002623 90.0
TLS3_k127_5921149_4 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000002427 73.0
TLS3_k127_5934776_0 PAS fold domain protein K21023 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 411.0
TLS3_k127_5934776_1 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 351.0
TLS3_k127_5934776_3 - - - - 0.00001196 50.0
TLS3_k127_5940451_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 5.264e-288 907.0
TLS3_k127_5940451_1 Aldehyde dehydrogenase family - - - 1.492e-224 714.0
TLS3_k127_5940451_2 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000008688 206.0
TLS3_k127_5940451_3 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.0000000000000000000000000000000000000000000000002128 181.0
TLS3_k127_5940451_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000001113 151.0
TLS3_k127_5940451_5 - - - - 0.00000000000000000000000000000000000004358 156.0
TLS3_k127_5940451_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000001368 135.0
TLS3_k127_5940451_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000005108 125.0
TLS3_k127_5940451_8 - - - - 0.0000000000000005323 81.0
TLS3_k127_5949306_0 Protein of unknown function (DUF998) - - - 0.00000000000000000000000000000000000000000000000000000000000000001305 232.0
TLS3_k127_5949306_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000001012 117.0
TLS3_k127_5949306_2 - - - - 0.0000000000000000005811 90.0
TLS3_k127_5949306_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate - - - 0.000000000001463 72.0
TLS3_k127_5950243_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 303.0
TLS3_k127_5950243_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000009437 117.0
TLS3_k127_5964206_0 - - - - 0.000000001478 66.0
TLS3_k127_5964206_1 - - - - 0.0000019 60.0
TLS3_k127_5996812_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 442.0
TLS3_k127_5996812_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000002899 227.0
TLS3_k127_5996812_2 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000000006838 229.0
TLS3_k127_5996812_3 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000225 213.0
TLS3_k127_5996812_4 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000004763 211.0
TLS3_k127_5996812_5 - - - - 0.0000000000000000000000000000000000000007621 152.0
TLS3_k127_5996812_6 - - - - 0.0000000000000000000001988 101.0
TLS3_k127_5996812_7 COG1520 FOG WD40-like repeat - - - 0.0000006943 58.0
TLS3_k127_6001398_0 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 437.0
TLS3_k127_6001398_1 Delta-aminolevulinic acid dehydratase K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009503 356.0
TLS3_k127_6001398_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749,K13542 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 0.00000001642 58.0
TLS3_k127_6011906_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 503.0
TLS3_k127_6011906_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 300.0
TLS3_k127_6020082_0 transferase activity, transferring glycosyl groups K16148 - 2.4.1.342 0.00000000000000000000000000000000000000000000000000002588 212.0
TLS3_k127_6020082_1 Sulfotransferase family - - - 0.0000000000000000000000005225 122.0
TLS3_k127_6020082_2 Aminoglycoside phosphotransferase K02204 - 2.7.1.39 0.0000000000001407 81.0
TLS3_k127_6027381_0 FAD-linked oxidoreductase K00103 - 1.1.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 518.0
TLS3_k127_6027381_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 489.0
TLS3_k127_6027381_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000001212 185.0
TLS3_k127_6046366_0 Belongs to the pseudouridine synthase RsuA family K06178,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000005214 263.0
TLS3_k127_6046366_1 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000001015 252.0
TLS3_k127_6046366_2 Chorismate mutase type I K06208 - 5.4.99.5 0.0000000000000000000000000000005166 126.0
TLS3_k127_6046366_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000001194 61.0
TLS3_k127_6046837_0 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007791 502.0
TLS3_k127_6046837_1 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 432.0
TLS3_k127_6046837_2 Acyl CoA acetate 3-ketoacid CoA K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 387.0
TLS3_k127_6046837_3 3-carboxy-cis,cis-muconate cycloisomerase K01857 - 5.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 374.0
TLS3_k127_6046837_4 Protocatechuate 3,4-dioxygenase, beta K00449 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 360.0
TLS3_k127_6046837_5 protocatechuate 3,4-dioxygenase K00448 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000000006472 239.0
TLS3_k127_60482_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.72e-260 814.0
TLS3_k127_60482_1 Type ii secretion system protein e K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004179 294.0
TLS3_k127_60482_2 Evidence 2b Function of strongly homologous gene K03406 - - 0.000000000000000000000000000000000000000000000000000002252 209.0
TLS3_k127_60482_3 PAC2 family - - - 0.00000000000000000000000000000000000000000000000004781 188.0
TLS3_k127_60482_4 PFAM Thioredoxin domain K05838 - - 0.00000000000000000000000000000000000000000000000006151 189.0
TLS3_k127_60482_5 Protein of unknown function (DUF2587) - - - 0.000000000000000000000000000000000005442 144.0
TLS3_k127_60482_6 peptidase K21471 - - 0.000000000000000000000000000000001635 144.0
TLS3_k127_60482_7 Thioesterase superfamily - - - 0.000000000000000000000000007601 117.0
TLS3_k127_60482_8 tetratricopeptide repeat - - - 0.00000001371 66.0
TLS3_k127_6077587_0 lysyltransferase activity K07027,K20468 - - 0.00000000004532 74.0
TLS3_k127_6082103_0 thiamine-containing compound biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 378.0
TLS3_k127_6082103_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001241 275.0
TLS3_k127_6082103_2 PFAM ABC transporter related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002071 264.0
TLS3_k127_6082103_3 CDP-alcohol phosphatidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000004274 236.0
TLS3_k127_6082103_4 PFAM Thiamin pyrophosphokinase, catalytic region K00949 - 2.7.6.2 0.000000000000000000009978 101.0
TLS3_k127_6082103_5 Thiamine-binding protein - - - 0.00000000000000000001074 98.0
TLS3_k127_611679_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K21159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 544.0
TLS3_k127_611679_1 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 404.0
TLS3_k127_611679_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008634 255.0
TLS3_k127_611679_3 - - - - 0.00000000000000000000000000000000000000006421 154.0
TLS3_k127_6118939_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 3.553e-278 882.0
TLS3_k127_6118939_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 453.0
TLS3_k127_6118939_2 NADPH quinone reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 326.0
TLS3_k127_6118939_3 ABC transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001035 290.0
TLS3_k127_6118939_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000001783 220.0
TLS3_k127_6118939_5 PFAM Alpha amylase, catalytic K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000001347 213.0
TLS3_k127_6118939_6 Universal stress protein - - - 0.0000000000000000001292 100.0
TLS3_k127_6119368_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 398.0
TLS3_k127_6119368_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 323.0
TLS3_k127_6119368_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 308.0
TLS3_k127_6119368_3 Protein of unknown function (DUF4031) - - - 0.000000000000000000000000001555 116.0
TLS3_k127_6119368_4 AsnC family - - - 0.0000000000000000000000000446 108.0
TLS3_k127_6119368_5 Ribosomal L28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000005437 95.0
TLS3_k127_6119368_6 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 0.0000000000000002996 87.0
TLS3_k127_6119368_7 GTP binding - - - 0.000005297 53.0
TLS3_k127_6124371_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 2.678e-280 878.0
TLS3_k127_6124371_1 Dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 458.0
TLS3_k127_6124371_10 - - - - 0.00004545 56.0
TLS3_k127_6124371_2 Ferredoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 430.0
TLS3_k127_6124371_3 Aminomethyltransferase folate-binding domain K00605 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 317.0
TLS3_k127_6124371_4 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000002576 246.0
TLS3_k127_6124371_5 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.00000000000000000000000000000000000001068 152.0
TLS3_k127_6124371_6 Belongs to the HesB IscA family K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564 - 0.00000000000000000000000000000000000008225 148.0
TLS3_k127_6124371_7 YbaK prolyl-tRNA synthetase associated region - - - 0.00000000000000000000000000000000008997 138.0
TLS3_k127_6124371_8 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00658 - 2.3.1.61 0.0000000000000002021 80.0
TLS3_k127_6124371_9 Belongs to the sulfur carrier protein TusA family K04487 - 2.8.1.7 0.000000000001334 73.0
TLS3_k127_6128195_0 Carbon starvation protein K06200 - - 5.513e-243 763.0
TLS3_k127_6128195_1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 612.0
TLS3_k127_6128195_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 441.0
TLS3_k127_6128195_3 Ribosomal protein S1-like RNA-binding domain K02945 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 424.0
TLS3_k127_6128195_4 - - - - 0.00000000000000000000000000000000000000004494 164.0
TLS3_k127_6128195_5 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000001322 153.0
TLS3_k127_6128195_6 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000673 167.0
TLS3_k127_6128195_7 - - - - 0.0000000000000000001103 103.0
TLS3_k127_6131904_0 PFAM LmbE family protein K18455 - 3.5.1.115 0.00000000000000000000000000000000000000000000000000002533 199.0
TLS3_k127_6131904_1 trans-aconitate 2-methyltransferase activity K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000004992 177.0
TLS3_k127_6131904_2 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000003899 176.0
TLS3_k127_6131904_3 Protein of unknown function (DUF2000) - - - 0.00000000000000000000000000000000000000001149 165.0
TLS3_k127_6131904_4 YacP-like NYN domain - - - 0.000000000000000002989 89.0
TLS3_k127_6138168_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.445e-208 661.0
TLS3_k127_6138168_1 PFAM Myo-inositol-1-phosphate synthase K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 562.0
TLS3_k127_6138168_10 PFAM EAL domain protein - - - 0.000000000000000000000000000000000000000000000001321 197.0
TLS3_k127_6138168_11 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog - - - 0.0000000000000000000000000000000000000000009258 165.0
TLS3_k127_6138168_12 Transcriptional regulator - - - 0.00000000000000000000000000000000000001068 152.0
TLS3_k127_6138168_13 Superoxide dismutase K00518 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.15.1.1 0.0000000000000000000000000000000000005641 153.0
TLS3_k127_6138168_14 Family of unknown function (DUF5318) - - - 0.00000000000000000004519 99.0
TLS3_k127_6138168_15 Acetyltransferase (GNAT) domain - - - 0.000000000000000001448 92.0
TLS3_k127_6138168_16 histidine kinase A domain protein - - - 0.00000000000000001743 97.0
TLS3_k127_6138168_17 - - - - 0.0000000000005183 75.0
TLS3_k127_6138168_18 Peptidase S24-like K03100 - 3.4.21.89 0.000000001237 66.0
TLS3_k127_6138168_19 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000718 50.0
TLS3_k127_6138168_2 4-alpha-glucanotransferase K00705 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 503.0
TLS3_k127_6138168_3 tRNA nucleotidyltransferase poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008838 510.0
TLS3_k127_6138168_4 PFAM Cytochrome b b6 domain K03891 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 358.0
TLS3_k127_6138168_5 Transglycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 367.0
TLS3_k127_6138168_6 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 337.0
TLS3_k127_6138168_7 Threonyl alanyl tRNA synthetase SAD K07050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 325.0
TLS3_k127_6138168_8 c reductase K03890 - - 0.000000000000000000000000000000000000000000000000000000007258 208.0
TLS3_k127_6138168_9 Cytochrome c K00406,K03889 - - 0.0000000000000000000000000000000000000000000000003177 191.0
TLS3_k127_6149425_0 Rieske-like [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000004859 186.0
TLS3_k127_6149425_1 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000021 178.0
TLS3_k127_6149425_2 PFAM LmbE family protein - - - 0.00000000000000000000006779 100.0
TLS3_k127_6184294_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090 - 0.0 1305.0
TLS3_k127_6184294_1 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001942 291.0
TLS3_k127_6193834_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 GO:0008150,GO:0040007 3.5.1.5 2.7e-299 923.0
TLS3_k127_6193834_1 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 GO:0003674,GO:0003824,GO:0003924,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 320.0
TLS3_k127_6193834_2 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.00000000000000000000000000000000000000000000000000001887 197.0
TLS3_k127_6210280_0 Phenazine biosynthesis protein PhzF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 338.0
TLS3_k127_6210280_1 20S proteasome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006771 320.0
TLS3_k127_6210280_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 291.0
TLS3_k127_6210280_3 PFAM cyclase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003342 241.0
TLS3_k127_6210280_4 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000000000004456 171.0
TLS3_k127_6210280_5 glyoxalase III activity - - - 0.00000000000000000000000004148 114.0
TLS3_k127_6213085_0 allantoinase K01466 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 511.0
TLS3_k127_6213085_1 Belongs to the allantoicase family K01477 - 3.5.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 418.0
TLS3_k127_6213085_2 Belongs to the HpcH HpaI aldolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 406.0
TLS3_k127_6213085_3 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin K00365 - 1.7.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002862 271.0
TLS3_k127_6213085_4 Transthyretin K07127 - 3.5.2.17 0.000000000000000000000000000001906 128.0
TLS3_k127_6235160_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 288.0
TLS3_k127_6235160_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000004607 220.0
TLS3_k127_6235160_2 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000006171 201.0
TLS3_k127_6240031_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009071 421.0
TLS3_k127_6240031_1 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001763 247.0
TLS3_k127_6240031_2 Binds the 23S rRNA K02909 - - 0.000000000000000000000000006593 111.0
TLS3_k127_6240638_0 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 623.0
TLS3_k127_6240638_1 Short chain fatty acid transporter K02106 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 512.0
TLS3_k127_6240638_2 Belongs to the glycosyl hydrolase family 6 K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949 324.0
TLS3_k127_6240638_3 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000816 326.0
TLS3_k127_6240638_4 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000003809 170.0
TLS3_k127_6240638_5 Protein of unknown function, DUF488 - - - 0.000000000000000000000003489 110.0
TLS3_k127_624269_0 FtsJ-like methyltransferase K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000003093 267.0
TLS3_k127_624269_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000003352 215.0
TLS3_k127_624269_2 May be involved in recombinational repair of damaged DNA K03631 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000006906 89.0
TLS3_k127_624269_3 Tetratricopeptide repeat - - - 0.0000000000000000138 87.0
TLS3_k127_624269_4 granule-associated protein - - - 0.0001658 50.0
TLS3_k127_6249933_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 447.0
TLS3_k127_6249933_1 Sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 426.0
TLS3_k127_6249933_2 Mur ligase, middle domain protein K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 327.0
TLS3_k127_6249933_3 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000001611 273.0
TLS3_k127_6249933_4 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000003297 220.0
TLS3_k127_6249933_5 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000001816 215.0
TLS3_k127_6249933_6 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine - - - 0.000000000000000000000000000000000000000000000000002153 196.0
TLS3_k127_6249933_7 redox protein regulator of disulfide bond formation K04063 - - 0.00000000000000000000000000000000000000001669 158.0
TLS3_k127_6249933_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000001013 77.0
TLS3_k127_6252959_0 PFAM FAD linked oxidase domain protein - - - 1.128e-201 638.0
TLS3_k127_6252959_1 Transcriptional regulator - - - 0.00000000000000000000000000000003777 131.0
TLS3_k127_6277974_0 Melibiase K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 522.0
TLS3_k127_6277974_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 519.0
TLS3_k127_6277974_10 Repeat of unknown function (DUF346) - - - 0.000000000000000000000000000000000000000000000000000000000000006302 241.0
TLS3_k127_6277974_11 PFAM sulfatase K01137 - 3.1.6.14 0.00000000000000000000000000000000000000000000000000000002709 221.0
TLS3_k127_6277974_12 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000008279 181.0
TLS3_k127_6277974_13 Haem-degrading - - - 0.000000000000000000000000000000001504 135.0
TLS3_k127_6277974_14 Histidine kinase - - - 0.00000000000000000000000000004841 124.0
TLS3_k127_6277974_15 sh3 domain protein K07282,K12132,K15539 - 2.7.11.1 0.0000000000000000000000006421 121.0
TLS3_k127_6277974_16 FR47-like protein - - - 0.0000000000000000006648 93.0
TLS3_k127_6277974_17 - - - - 0.00000000000000006102 83.0
TLS3_k127_6277974_2 Bacterial extracellular solute-binding protein K17315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 457.0
TLS3_k127_6277974_3 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 449.0
TLS3_k127_6277974_4 PFAM binding-protein-dependent transport systems inner membrane component K17316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 387.0
TLS3_k127_6277974_5 Binding-protein-dependent transport system inner membrane component K17317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 384.0
TLS3_k127_6277974_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 355.0
TLS3_k127_6277974_7 beta-fructofuranosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 339.0
TLS3_k127_6277974_8 Pfam Ion transport protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002301 283.0
TLS3_k127_6277974_9 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) K03335 - 4.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000001639 250.0
TLS3_k127_6287596_0 Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006376 425.0
TLS3_k127_6287596_1 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 396.0
TLS3_k127_6287596_2 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001037 269.0
TLS3_k127_6287596_3 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000001494 249.0
TLS3_k127_6296387_0 ATPases associated with a variety of cellular activities K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 436.0
TLS3_k127_6296387_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000401 242.0
TLS3_k127_6296387_2 PFAM extracellular solute-binding protein family 1 K10232 - - 0.00000000000000000000000000000000000000000000000001668 192.0
TLS3_k127_6296387_3 PFAM mannose-6-phosphate isomerase type I K01809 - 5.3.1.8 0.000000000000000000000000000000000000000000002513 178.0
TLS3_k127_6296387_4 pyridoxamine 5-phosphate K05558 - - 0.000000000000000000000000000000000000000000003137 168.0
TLS3_k127_6296387_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000002602 171.0
TLS3_k127_6296387_6 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000006736 157.0
TLS3_k127_6296387_7 AAA ATPase domain - - - 0.000000000000000000000000000000000002066 149.0
TLS3_k127_6296387_8 Bacterial transcriptional activator domain - - - 0.0000000002189 71.0
TLS3_k127_6299805_0 acyl-CoA dehydrogenase K00248 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 477.0
TLS3_k127_6299805_1 Acyl-CoA hydrolase K01075,K10806 - 3.1.2.23 0.000000000000000000000000000000000000009745 155.0
TLS3_k127_630261_0 Glycosyl hydrolase family 115 - - - 0.0 1449.0
TLS3_k127_630261_1 sequence-specific DNA binding - - - 0.000000000000174 85.0
TLS3_k127_6313948_0 COG0618 Exopolyphosphatase-related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 446.0
TLS3_k127_6313948_1 Putative sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 361.0
TLS3_k127_6313948_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 324.0
TLS3_k127_6313948_3 Pfam Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005793 268.0
TLS3_k127_6313948_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.00004626 46.0
TLS3_k127_6321699_0 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004245 292.0
TLS3_k127_6321699_1 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000005922 231.0
TLS3_k127_6321699_2 PKD domain - - - 0.000000000000000000000000000000000000000000001543 190.0
TLS3_k127_6321699_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000006179 161.0
TLS3_k127_6321699_4 F5/8 type C domain K01206 - 3.2.1.51 0.00000000000000000009286 106.0
TLS3_k127_6321699_5 Amidase K01426 - 3.5.1.4 0.00000000000000001542 89.0
TLS3_k127_6321699_6 AAA domain K03609 - - 0.00002376 57.0
TLS3_k127_6325630_0 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000001511 211.0
TLS3_k127_6326323_0 Sigma-70 region 2 - - - 4.639e-196 619.0
TLS3_k127_6326323_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 - 3.2.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001018 286.0
TLS3_k127_6326323_2 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000002461 207.0
TLS3_k127_6326323_3 - - - - 0.00000000000000000000004825 115.0
TLS3_k127_6344307_0 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000004194 162.0
TLS3_k127_6344307_1 - - - - 0.0000000003461 73.0
TLS3_k127_6345385_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1319.0
TLS3_k127_6345385_1 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007114 398.0
TLS3_k127_6345385_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 291.0
TLS3_k127_6370396_0 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000007677 239.0
TLS3_k127_6370396_1 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000208 151.0
TLS3_k127_6370396_2 Domain of Unknown Function (DUF1206) - - - 0.00000000000000000000000000000000435 138.0
TLS3_k127_6384712_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 598.0
TLS3_k127_6384712_1 Acetohydroxy acid isomeroreductase, NADPH-binding domain K06988 - 1.5.1.40 0.00000000000000000000000000000000002943 143.0
TLS3_k127_6384712_2 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000004378 56.0
TLS3_k127_6384712_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0006387 51.0
TLS3_k127_6387946_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006572 382.0
TLS3_k127_6387946_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 334.0
TLS3_k127_6387946_2 Cellulose biosynthesis protein BcsQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005457 259.0
TLS3_k127_6387946_3 acetyltransferase K03825 - - 0.00000000000000000000000000000000005485 142.0
TLS3_k127_6387946_4 PFAM helix-turn-helix HxlR type - - - 0.00000000000000000000000000233 125.0
TLS3_k127_6387946_5 - - - - 0.000000000000000000000000004071 120.0
TLS3_k127_6387946_6 SnoaL-like domain - - - 0.00002123 56.0
TLS3_k127_6387946_7 Domain of unknown function (DUF427) - - - 0.00004824 51.0
TLS3_k127_6387946_8 Domain of unknown function (DUF427) - - - 0.0005371 47.0
TLS3_k127_6389013_0 Belongs to the CarB family K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0 1263.0
TLS3_k127_6389013_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006265 413.0
TLS3_k127_6389013_2 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 415.0
TLS3_k127_6389013_3 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 413.0
TLS3_k127_6389013_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000002113 237.0
TLS3_k127_6389013_5 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000002721 211.0
TLS3_k127_6389013_6 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000002232 143.0
TLS3_k127_6390488_0 CopC domain K14166 - - 0.00000000000000000000000000000000000000000000249 189.0
TLS3_k127_6390488_1 - - - - 0.0000000000000000000000000000000000006019 157.0
TLS3_k127_6390488_2 Putative zinc-finger K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000001061 64.0
TLS3_k127_6402638_0 Belongs to the peptidase S8 family - - - 4.726e-290 922.0
TLS3_k127_6402638_1 UPF0365 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 460.0
TLS3_k127_6402638_2 Membrane-bound serine protease (ClpP class) K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 374.0
TLS3_k127_6402638_3 helix_turn _helix lactose operon repressor - - - 0.000000000000000000000000000000000000001563 158.0
TLS3_k127_6410732_0 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000004465 269.0
TLS3_k127_6410732_1 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000000001784 173.0
TLS3_k127_6410732_2 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.000003249 55.0
TLS3_k127_6439352_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.402e-229 725.0
TLS3_k127_6439352_1 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 299.0
TLS3_k127_6439352_2 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000000000000000000000000000000000002462 166.0
TLS3_k127_6439352_3 response regulator - - - 0.0000000000000000000000000000000000000302 154.0
TLS3_k127_6439352_4 Histidine kinase - - - 0.0000000000000000000004169 111.0
TLS3_k127_6440257_0 pfkB family carbohydrate kinase K03338 - 2.7.1.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 472.0
TLS3_k127_6440257_1 Deoxyribose-phosphate aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 385.0
TLS3_k127_6440257_2 NmrA-like family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 348.0
TLS3_k127_6440257_3 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 300.0
TLS3_k127_6440257_4 PFAM Myo-inositol catabolism IolB domain protein K03337 - 5.3.1.30 0.0000000000000000000000000000002144 138.0
TLS3_k127_6457170_0 Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta K01969 - 6.4.1.4 2.419e-275 858.0
TLS3_k127_6457170_1 Acetyl propionyl-CoA carboxylase, alpha subunit K11263 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.4.14,6.4.1.2,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001383 278.0
TLS3_k127_6457170_2 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.00000000000000000000000000000000000000000000000000000000000000000002059 242.0
TLS3_k127_6457170_3 acetyltransferase - - - 0.000000000000000000000000000000000000000003503 159.0
TLS3_k127_6463389_0 transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000001753 242.0
TLS3_k127_647118_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.099e-224 703.0
TLS3_k127_647118_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 400.0
TLS3_k127_647118_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00271 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.4.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 308.0
TLS3_k127_647118_3 PFAM helix-turn-helix HxlR type - - - 0.0000000000000000000000000000000000004937 157.0
TLS3_k127_647118_4 - - - - 0.00000000000000000000003122 109.0
TLS3_k127_6475092_0 Glycosyl hydrolase family 3 C-terminal domain K05349 - 3.2.1.21 1.604e-226 726.0
TLS3_k127_6475092_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002271 248.0
TLS3_k127_6475092_2 Sterol carrier protein domain - - - 0.000000000000000000000000000000000000000000000000000000000002237 224.0
TLS3_k127_6475092_3 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000002024 208.0
TLS3_k127_6496087_0 Male sterility protein K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 440.0
TLS3_k127_6496087_1 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 434.0
TLS3_k127_6496087_2 N-acyl-D-aspartate D-glutamate deacylase K01465,K06015 - 3.5.1.81,3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 405.0
TLS3_k127_6496087_3 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K21210 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000505 279.0
TLS3_k127_6496087_4 sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family - - - 0.0000000000000000000000000000000004242 151.0
TLS3_k127_6498854_0 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002391 269.0
TLS3_k127_6498854_1 NMT1-like family K02051 - - 0.000000000000000000000000000001651 137.0
TLS3_k127_6498854_2 proline dipeptidase activity K01262 - 3.4.11.9 0.000000000000000000000177 108.0
TLS3_k127_6500757_0 SpoIID LytB domain protein - - - 0.000000000000000000000000000000000008918 156.0
TLS3_k127_6500757_1 Belongs to the peptidase S8 family K14645,K14743 - - 0.000000000000000000000000001189 124.0
TLS3_k127_6500757_2 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000003206 93.0
TLS3_k127_6500757_3 S-layer homology domain - - - 0.000002315 61.0
TLS3_k127_6503270_0 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000001183 206.0
TLS3_k127_6503270_1 Trypsin-like serine protease - - - 0.0000000000000000000001077 109.0
TLS3_k127_6521059_0 Signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 437.0
TLS3_k127_6521197_0 PFAM NLP P60 protein K21471 GO:0005575,GO:0005576 - 0.00000000000000000000000000000000001161 149.0
TLS3_k127_6521197_1 - - - - 0.000000000000000000001968 102.0
TLS3_k127_6525106_0 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 353.0
TLS3_k127_6525106_1 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000001669 158.0
TLS3_k127_6525106_2 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000001563 120.0
TLS3_k127_6525106_3 Domain of unknown function (DUF2017) - - - 0.000001007 57.0
TLS3_k127_6528706_0 FAD linked oxidase domain protein K00103,K00594 - 1.1.3.41,1.1.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009014 458.0
TLS3_k127_6528706_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 453.0
TLS3_k127_6528706_2 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 421.0
TLS3_k127_6528706_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 392.0
TLS3_k127_6528706_4 Oligopeptide/dipeptide transporter, C-terminal region K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 374.0
TLS3_k127_6528706_5 trisaccharide binding - - - 0.00000000000000000000000000516 119.0
TLS3_k127_6567641_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 2.75e-308 974.0
TLS3_k127_6567641_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 575.0
TLS3_k127_6567641_10 tetraacyldisaccharide 4'-kinase activity K00912,K09791 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.1.130 0.000000000002569 69.0
TLS3_k127_6567641_11 Phosphoribosyl transferase domain - - - 0.00000000004674 76.0
TLS3_k127_6567641_12 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000874 68.0
TLS3_k127_6567641_13 Protein of unknown function (DUF3499) - - - 0.000000003857 67.0
TLS3_k127_6567641_14 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.000009857 58.0
TLS3_k127_6567641_2 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 521.0
TLS3_k127_6567641_3 ATPase family associated with various cellular activities (AAA) K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 460.0
TLS3_k127_6567641_4 helix_turn_helix, Lux Regulon K02479 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 305.0
TLS3_k127_6567641_5 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 324.0
TLS3_k127_6567641_6 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000007808 205.0
TLS3_k127_6567641_7 Sugar isomerase (SIS) K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000004751 192.0
TLS3_k127_6567641_8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000007969 165.0
TLS3_k127_6567641_9 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.0000000000000000000000000000009804 122.0
TLS3_k127_6570851_0 sugar phosphate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 419.0
TLS3_k127_6570851_1 Domain of unknown function DUF21 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 361.0
TLS3_k127_6570851_2 lipopolysaccharide transmembrane transporter activity K07058 - - 0.00000000000000000000000000000000000000000000000000004503 200.0
TLS3_k127_6570851_3 GGDEF domain - - - 0.0000000000000000000000000000000000004762 158.0
TLS3_k127_6571245_0 Phosphotransferase system, EIIC K02798,K02799,K02800 - 2.7.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 484.0
TLS3_k127_6571245_1 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 434.0
TLS3_k127_6571245_2 DeoR C terminal sensor domain K03436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 310.0
TLS3_k127_6571245_3 Scramblase - - - 0.00000000000000000000000000000000000000000002328 169.0
TLS3_k127_6571245_4 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02768,K02798,K11183 - 2.7.1.197,2.7.1.202 0.0000000000000000000000000000000000000448 151.0
TLS3_k127_6571245_5 PTS system, Lactose/Cellobiose specific IIB subunit K02799 - 2.7.1.197 0.0000000000000000000000000000000002217 134.0
TLS3_k127_6575924_0 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008256 332.0
TLS3_k127_6575924_1 PFAM ADP-ribosylation Crystallin J1 - - - 0.00000000000000000805 91.0
TLS3_k127_6597317_0 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 500.0
TLS3_k127_6597317_1 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 421.0
TLS3_k127_6597317_2 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 345.0
TLS3_k127_6597317_3 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001628 240.0
TLS3_k127_6597317_4 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000008772 216.0
TLS3_k127_6597317_5 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000002628 214.0
TLS3_k127_6597317_6 Acetyltransferase (GNAT) domain K00657,K00663 - 2.3.1.57,2.3.1.82 0.0000000000000000000000000000000000000000000002853 172.0
TLS3_k127_6597317_7 ABC transporter - - - 0.0000000000007986 81.0
TLS3_k127_6597317_8 transcriptional regulator - - - 0.000002738 50.0
TLS3_k127_662445_0 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 297.0
TLS3_k127_662445_1 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000003243 213.0
TLS3_k127_6633302_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 4.221e-239 755.0
TLS3_k127_6633302_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006956 285.0
TLS3_k127_6633302_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000006303 274.0
TLS3_k127_6633302_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000157 266.0
TLS3_k127_6633302_4 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000007313 241.0
TLS3_k127_6633302_5 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000088 199.0
TLS3_k127_6633302_6 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000001004 186.0
TLS3_k127_6633302_7 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000007817 158.0
TLS3_k127_6633302_8 Zn peptidase - - - 0.00000000000000000000000000000000000005348 160.0
TLS3_k127_6633302_9 Dihydroneopterin aldolase K01633,K13940 GO:0008150,GO:0040007 1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8 0.00000000000000000000004089 113.0
TLS3_k127_6636386_0 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 513.0
TLS3_k127_6636386_1 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 427.0
TLS3_k127_6636386_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 362.0
TLS3_k127_6636386_3 metallophosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001029 250.0
TLS3_k127_6636386_4 PAS fold domain protein K21023 - 2.7.7.65 0.00000000000000000000000000000000000005918 158.0
TLS3_k127_6636386_5 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form - - - 0.0000000000000000000000000000000000001549 146.0
TLS3_k127_6636386_6 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000008204 113.0
TLS3_k127_6636386_7 MazG nucleotide pyrophosphohydrolase domain - - - 0.00000000000000000000004906 102.0
TLS3_k127_6642163_0 Penicillin amidase K01434 - 3.5.1.11 9.741e-260 830.0
TLS3_k127_6642163_1 5'-nucleotidase, C-terminal domain K01081,K01119 - 3.1.3.5,3.1.3.6,3.1.4.16 0.0002741 50.0
TLS3_k127_664235_0 Glutamine synthetase, beta-Grasp domain K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 1.386e-197 627.0
TLS3_k127_664235_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 552.0
TLS3_k127_6661669_0 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 484.0
TLS3_k127_6661669_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008637 325.0
TLS3_k127_6661669_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000003049 211.0
TLS3_k127_6661669_3 Single-stranded DNA-binding protein K03111 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000001005 171.0
TLS3_k127_6661669_4 glutamine amidotransferase - - - 0.0000000000000000000000000000000000005493 153.0
TLS3_k127_6661669_5 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000004768 133.0
TLS3_k127_6661669_6 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000001296 98.0
TLS3_k127_6661669_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000002963 97.0
TLS3_k127_6661669_8 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000049 95.0
TLS3_k127_6666677_0 DNA ligase - GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 508.0
TLS3_k127_6666677_1 DNA primase, small subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 370.0
TLS3_k127_6670512_0 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 435.0
TLS3_k127_6670512_1 WD-40 repeat-containing protein K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 385.0
TLS3_k127_6670512_2 Protein of unknown function (DUF4231) - - - 0.0000000000000000000000000000000009238 135.0
TLS3_k127_6670512_3 COGs COG1476 transcriptional regulator protein - - - 0.000000001316 64.0
TLS3_k127_6670512_4 - - - - 0.0000001154 60.0
TLS3_k127_6670512_5 Lamin Tail Domain - - - 0.00005684 55.0
TLS3_k127_6679105_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1118.0
TLS3_k127_6679105_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008902 253.0
TLS3_k127_6690034_0 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 350.0
TLS3_k127_6690034_1 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 303.0
TLS3_k127_6690034_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005362 278.0
TLS3_k127_6690034_3 Pfam:Pyridox_oxidase K05558 - - 0.0000000000000000000000000000000000000000000000000000000000000006336 223.0
TLS3_k127_6690034_4 Multicopper oxidase K00368 - 1.7.2.1 0.0000001128 61.0
TLS3_k127_6692511_0 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 332.0
TLS3_k127_6692511_1 Vitamin K-dependent gamma-carboxylase - - - 0.0000000004673 71.0
TLS3_k127_6708777_0 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 357.0
TLS3_k127_6708777_1 pfam abc K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 374.0
TLS3_k127_6708777_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009623 367.0
TLS3_k127_6708777_3 AMP-forming long-chain acyl-CoA synthetase K01897 - 6.2.1.3 0.0000000000000000000000000005485 119.0
TLS3_k127_6714831_0 AAA ATPase K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 335.0
TLS3_k127_6714831_1 Virulence factor BrkB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001325 281.0
TLS3_k127_6714831_2 - - - - 0.000000000000000000000000000000000006242 141.0
TLS3_k127_6714831_3 Xylose isomerase-like TIM barrel - - - 0.0000000000000002523 79.0
TLS3_k127_6744278_0 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000002701 202.0
TLS3_k127_6744278_1 Protein of unknown function (DUF2630) - - - 0.0000000000000000001928 91.0
TLS3_k127_6745993_0 SNF2 family N-terminal domain - - - 0.0 1075.0
TLS3_k127_6745993_1 Permease for cytosine purines, uracil, thiamine, allantoin K10974 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 555.0
TLS3_k127_6745993_10 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000004283 173.0
TLS3_k127_6745993_11 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 0.000000000000000000000000000000000004934 151.0
TLS3_k127_6745993_2 Animal haem peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006981 559.0
TLS3_k127_6745993_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 416.0
TLS3_k127_6745993_4 S-adenosyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 309.0
TLS3_k127_6745993_5 MafB19-like deaminase K01485 - 3.5.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000004016 254.0
TLS3_k127_6745993_6 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002147 251.0
TLS3_k127_6745993_7 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000772 205.0
TLS3_k127_6745993_8 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000003314 181.0
TLS3_k127_6745993_9 RibD C-terminal domain K14654 - 1.1.1.302 0.00000000000000000000000000000000000000000000001312 178.0
TLS3_k127_6746489_0 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 468.0
TLS3_k127_6746489_1 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008819 458.0
TLS3_k127_6746489_10 Transcriptional regulator PadR-like family K10947 - - 0.0000000000000000000000000000000000004821 148.0
TLS3_k127_6746489_11 Carboxymuconolactone decarboxylase family - - - 0.00000002541 66.0
TLS3_k127_6746489_12 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000003407 57.0
TLS3_k127_6746489_13 hydroperoxide reductase activity - - - 0.00003748 50.0
TLS3_k127_6746489_2 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 378.0
TLS3_k127_6746489_3 ATPases associated with a variety of cellular activities K15555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 337.0
TLS3_k127_6746489_4 SpoU rRNA Methylase family K00556 - 2.1.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 325.0
TLS3_k127_6746489_5 NMT1/THI5 like - - - 0.000000000000000000000000000000000000000000000000000000000000000007105 240.0
TLS3_k127_6746489_6 - - - - 0.0000000000000000000000000000000000000000000000000000000002208 222.0
TLS3_k127_6746489_7 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000003024 184.0
TLS3_k127_6746489_8 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000003204 166.0
TLS3_k127_6746489_9 SnoaL-like domain - - - 0.0000000000000000000000000000000000000009777 154.0
TLS3_k127_6753342_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.7.7.8 6.015e-251 801.0
TLS3_k127_6753342_1 Cellulase (glycosyl hydrolase family 5) K19355 - 3.2.1.78 1.518e-200 646.0
TLS3_k127_6753342_10 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000793 222.0
TLS3_k127_6753342_11 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.0000000000000000000000000000000002347 134.0
TLS3_k127_6753342_12 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000867 113.0
TLS3_k127_6753342_13 Protein of unknown function (DUF503) K09764 - - 0.000000000000001889 79.0
TLS3_k127_6753342_2 Ftsk_gamma K03466 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 606.0
TLS3_k127_6753342_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 537.0
TLS3_k127_6753342_4 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 508.0
TLS3_k127_6753342_5 Insulinase (Peptidase family M16) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 445.0
TLS3_k127_6753342_6 DHH family K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007751 297.0
TLS3_k127_6753342_7 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008292 283.0
TLS3_k127_6753342_8 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000718 264.0
TLS3_k127_6753342_9 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000004589 231.0
TLS3_k127_6753707_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 514.0
TLS3_k127_6753707_1 Belongs to the glycosyl hydrolase family 6 K14194,K14201 GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0044877,GO:0051704,GO:0070051,GO:0098630,GO:0098743 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 328.0
TLS3_k127_6753707_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001165 285.0
TLS3_k127_6753707_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001174 275.0
TLS3_k127_6765093_0 Histidine kinase K02478,K07704 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 473.0
TLS3_k127_6765093_1 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 307.0
TLS3_k127_6788870_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.00000000000000000000000000000000000000000005957 168.0
TLS3_k127_6788870_2 Plasmid stability protein K21495 - - 0.0000000000004954 80.0
TLS3_k127_6788870_3 amidohydrolase K03392 - 4.1.1.45 0.000001186 55.0
TLS3_k127_6788870_4 3-demethylubiquinone-9 3-methyltransferase - - - 0.00003863 55.0
TLS3_k127_6788870_5 D-isomer specific 2-hydroxyacid dehydrogenase K03778 - 1.1.1.28 0.0001514 48.0
TLS3_k127_6795029_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 362.0
TLS3_k127_6795029_1 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001795 276.0
TLS3_k127_6795029_2 HrcA protein C terminal domain K03705 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000002266 241.0
TLS3_k127_6800966_0 Peptidase M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 539.0
TLS3_k127_6800966_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 453.0
TLS3_k127_6800966_2 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 371.0
TLS3_k127_6800966_3 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 339.0
TLS3_k127_6800966_4 - - - - 0.00000004285 67.0
TLS3_k127_680421_0 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 448.0
TLS3_k127_680421_1 Sortase family - - - 0.000000000000000000000000000000000000000001248 166.0
TLS3_k127_680421_2 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000001049 78.0
TLS3_k127_680421_3 DoxX family - - - 0.00003153 47.0
TLS3_k127_6827946_0 Sigma-70 region 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 566.0
TLS3_k127_6827946_1 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 547.0
TLS3_k127_6827946_10 YCII-related domain - - - 0.0000000000000000000000000000000000000000000005619 168.0
TLS3_k127_6827946_11 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000009851 167.0
TLS3_k127_6827946_12 PhoQ Sensor - - - 0.0000000000000000000000000000000000000007271 167.0
TLS3_k127_6827946_13 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.00000000000000000000000000000000911 141.0
TLS3_k127_6827946_14 Histidine kinase - - - 0.00000000000000000000000000000002716 144.0
TLS3_k127_6827946_15 - - - - 0.000000000000000000003901 99.0
TLS3_k127_6827946_16 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000008347 74.0
TLS3_k127_6827946_17 Intracellular proteinase inhibitor - - - 0.000001346 56.0
TLS3_k127_6827946_2 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 450.0
TLS3_k127_6827946_3 WD-40 repeat-containing protein K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 432.0
TLS3_k127_6827946_4 Pentapeptide repeats (8 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 346.0
TLS3_k127_6827946_5 phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 346.0
TLS3_k127_6827946_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000008151 211.0
TLS3_k127_6827946_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000001606 208.0
TLS3_k127_6827946_8 PFAM DsrE DsrF-like family - - - 0.000000000000000000000000000000000000000000000000000003137 196.0
TLS3_k127_6827946_9 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000001315 173.0
TLS3_k127_6831919_0 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000006247 122.0
TLS3_k127_6831919_1 zinc ion binding K06204 - - 0.00000000003479 70.0
TLS3_k127_6837326_0 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 443.0
TLS3_k127_6837326_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000007474 179.0
TLS3_k127_6837326_2 interspecies interaction between organisms K18353 - - 0.00000000000000000000000000000000000003908 158.0
TLS3_k127_6837326_3 protein with SCP PR1 domains - - - 0.0000000000009648 82.0
TLS3_k127_6840801_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K01281 - 3.4.14.11 9.551e-271 844.0
TLS3_k127_6840801_1 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 4.561e-262 826.0
TLS3_k127_6840801_2 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 377.0
TLS3_k127_6840801_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000005076 119.0
TLS3_k127_6841660_0 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 566.0
TLS3_k127_6841660_1 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000003637 159.0
TLS3_k127_6841660_2 Trehalose corynomycolyl transferase - - - 0.00000000021 64.0
TLS3_k127_6841660_3 - - - - 0.000000009519 65.0
TLS3_k127_6844889_0 Lipase maturation factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 582.0
TLS3_k127_6844889_1 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 454.0
TLS3_k127_6844889_2 Transport permease protein K01992,K18233 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 356.0
TLS3_k127_6844889_3 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008623 253.0
TLS3_k127_6844889_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000001984 200.0
TLS3_k127_6844889_5 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000002583 196.0
TLS3_k127_6844889_6 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000002869 172.0
TLS3_k127_6844889_7 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.000000000000000000001623 99.0
TLS3_k127_6844889_8 - K22014 - - 0.000001671 55.0
TLS3_k127_6851128_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 456.0
TLS3_k127_6851128_1 abc transporter atp-binding protein K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 398.0
TLS3_k127_6851128_2 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) K05845 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001031 251.0
TLS3_k127_6851128_3 permease K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000009013 252.0
TLS3_k127_6851128_4 homocysteine K00547,K21169 - 2.1.1.10 0.00000000000000000000000000000000000000000000000000001738 197.0
TLS3_k127_6851128_5 transport K05845,K05846 - - 0.000000000000000000000000000000000000000000000000002588 200.0
TLS3_k127_6851128_6 GDP-mannose mannosyl hydrolase activity - - - 0.000000000000000000000000000000000000000004991 174.0
TLS3_k127_685195_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 2.805e-249 781.0
TLS3_k127_685195_1 Clp amino terminal domain, pathogenicity island component K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 1.262e-207 654.0
TLS3_k127_685195_2 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 568.0
TLS3_k127_685195_3 Sodium:sulfate symporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 557.0
TLS3_k127_685195_4 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 319.0
TLS3_k127_685195_5 Phosphotransferase enzyme family K00897 - 2.7.1.95 0.00000000000000000000000000000000000000000001439 176.0
TLS3_k127_685195_6 Family of unknown function (DUF5319) - - - 0.0000000000000000000000016 113.0
TLS3_k127_685195_7 Methyltransferase K16437,K21336 - - 0.00001443 53.0
TLS3_k127_6888311_0 Beta-lactamase K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 419.0
TLS3_k127_6888311_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007142 244.0
TLS3_k127_6888311_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.000000000000000000000103 105.0
TLS3_k127_6933875_0 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 556.0
TLS3_k127_6933875_1 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 406.0
TLS3_k127_6933875_10 dehydratase - - - 0.00000000000000000000000000000000000000000000000001057 186.0
TLS3_k127_6933875_11 - - - - 0.00000000000000000000000000000000000000000000000001707 193.0
TLS3_k127_6933875_12 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000004643 177.0
TLS3_k127_6933875_13 transcriptional regulator - - - 0.0000000000000000000000000001437 121.0
TLS3_k127_6933875_14 - - - - 0.000000000000000000000000000454 125.0
TLS3_k127_6933875_15 YCII-related domain - - - 0.00000000000000009118 91.0
TLS3_k127_6933875_16 Archease protein family (MTH1598/TM1083) - - - 0.000000000000009582 89.0
TLS3_k127_6933875_17 Carboxypeptidase regulatory-like domain - - - 0.00000000000001539 78.0
TLS3_k127_6933875_18 - - - - 0.00000000001309 74.0
TLS3_k127_6933875_2 Belongs to the peptidase S1B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 350.0
TLS3_k127_6933875_3 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 338.0
TLS3_k127_6933875_4 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 295.0
TLS3_k127_6933875_5 Belongs to the peptidase S8 family K08651,K14645 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001055 293.0
TLS3_k127_6933875_6 5'-3' exonuclease - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000001431 224.0
TLS3_k127_6933875_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000003624 219.0
TLS3_k127_6933875_8 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000000000000000000000000000000001978 218.0
TLS3_k127_6933875_9 - - - - 0.00000000000000000000000000000000000000000000000000003203 212.0
TLS3_k127_6943952_0 Cation transport ATPase (P-type) K01537 - 3.6.3.8 1.69e-295 938.0
TLS3_k127_6943952_1 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 396.0
TLS3_k127_6943952_10 Domain of unknown function (DUF1905) - - - 0.000000000000000000000000000000001089 132.0
TLS3_k127_6943952_11 Protein of unknown function (DUF1761) - - - 0.00000000000000000000000000000001627 130.0
TLS3_k127_6943952_12 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000002547 103.0
TLS3_k127_6943952_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 313.0
TLS3_k127_6943952_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 305.0
TLS3_k127_6943952_4 Abc-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000335 285.0
TLS3_k127_6943952_5 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004534 247.0
TLS3_k127_6943952_6 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004723 250.0
TLS3_k127_6943952_7 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000001055 230.0
TLS3_k127_6943952_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000586 199.0
TLS3_k127_6943952_9 PFAM peptidase K21471 - - 0.000000000000000000000000000000000000000003411 165.0
TLS3_k127_6976812_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 429.0
TLS3_k127_6976812_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000001987 213.0
TLS3_k127_6977062_0 AMP-binding enzyme K01907 - 6.2.1.16 1.911e-204 655.0
TLS3_k127_6977062_1 Major facilitator superfamily K08167 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 620.0
TLS3_k127_6977062_2 L-carnitine dehydratase bile acid-inducible protein F K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000065 414.0
TLS3_k127_6977062_3 Domain of unknown function (DUF4916) - - - 0.00000000000000000000000000000000000000000000000000000000001874 219.0
TLS3_k127_6977062_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 0.000000000000000000000000000000000000000000000000000005798 194.0
TLS3_k127_6977062_5 NUDIX hydrolase - - - 0.00000000000000000000000000001124 124.0
TLS3_k127_6996770_0 Zn_pept - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 575.0
TLS3_k127_6996770_1 Efflux ABC transporter, permease protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 433.0
TLS3_k127_6996770_2 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 291.0
TLS3_k127_6996770_3 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002141 290.0
TLS3_k127_6996770_4 Histidine kinase - - - 0.00000000000000000000000000001019 136.0
TLS3_k127_7005818_0 Transcriptional regulator K02624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 355.0
TLS3_k127_7005818_1 decarboxylase K01607,K14727 - 3.1.1.24,4.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 304.0
TLS3_k127_7005818_2 decarboxylase K01607,K14727 - 3.1.1.24,4.1.1.44 0.0000000000000000000000000000000000000000000000001621 182.0
TLS3_k127_7005818_3 3-carboxy-cis,cis-muconate cycloisomerase K01857 - 5.5.1.2 0.000000000001365 70.0
TLS3_k127_7010929_0 Belongs to the transketolase family K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006447 502.0
TLS3_k127_7010929_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K03778 - 1.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 404.0
TLS3_k127_7010929_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 319.0
TLS3_k127_7010929_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 309.0
TLS3_k127_7010929_4 Belongs to the transketolase family K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009457 306.0
TLS3_k127_7027755_0 Type III restriction enzyme, res subunit - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009575 580.0
TLS3_k127_7027755_1 TIGRFAM sugar-phosphate isomerase, RpiB LacA LacB family K01808 - 5.3.1.6 0.00000000000000000000000000000005447 142.0
TLS3_k127_7027755_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000002361 140.0
TLS3_k127_7029377_0 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001158 291.0
TLS3_k127_7029377_1 Domain of unkown function (DUF1775) K09796 - - 0.0000000000000000000000000000000000001896 155.0
TLS3_k127_7029377_2 RDD family - - - 0.0000000000000000000000000000000001897 142.0
TLS3_k127_7037087_0 Molybdopterin dehydrogenase K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 292.0
TLS3_k127_7037087_1 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000002292 249.0
TLS3_k127_7075751_0 Evidence 2b Function of strongly homologous gene K05343 - 3.2.1.1,5.4.99.16 1.826e-225 717.0
TLS3_k127_7075751_1 PFAM Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 466.0
TLS3_k127_7075751_2 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 415.0
TLS3_k127_7075751_3 Acetamidase formamidase K01455 - 3.5.1.49 0.0000000000000000009838 87.0
TLS3_k127_708321_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 5.64e-210 666.0
TLS3_k127_708321_1 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 620.0
TLS3_k127_708321_2 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000005052 229.0
TLS3_k127_708321_3 Acyl transferase domain K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000001083 220.0
TLS3_k127_708321_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000001206 137.0
TLS3_k127_7095194_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 556.0
TLS3_k127_7095194_1 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000004502 231.0
TLS3_k127_7095194_2 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000000000000000000000001226 185.0
TLS3_k127_7095194_3 Transcriptional Regulator AraC Family - - - 0.0000000000000000000000000000000000001718 154.0
TLS3_k127_7095194_4 PFAM regulatory protein TetR - - - 0.0000004728 59.0
TLS3_k127_7096126_0 synthase K02228 - 2.1.1.152 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 338.0
TLS3_k127_7096126_1 precorrin-6x reductase K05895 - 1.3.1.106,1.3.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007888 284.0
TLS3_k127_7096126_2 Siderophore-interacting protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000003124 232.0
TLS3_k127_7096126_3 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.0000000000000007631 80.0
TLS3_k127_7100557_0 WD40 repeats - - - 0.0 1262.0
TLS3_k127_7100557_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 321.0
TLS3_k127_7100557_2 Helix-turn-helix diphteria tox regulatory element K03709 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000002242 228.0
TLS3_k127_7100557_3 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000000000001517 225.0
TLS3_k127_7100557_4 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000005716 199.0
TLS3_k127_7100557_5 Methyltransferase domain - - - 0.0000000000000000000000000000000003137 145.0
TLS3_k127_7100557_6 Alpha/beta hydrolase family K07020 - - 0.000000000000000000000000000000112 138.0
TLS3_k127_7100557_7 - - - - 0.000000000000000000000000003248 123.0
TLS3_k127_7100557_8 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000001085 121.0
TLS3_k127_7100557_9 Transglycosylase associated protein - - - 0.00000000000000000003183 93.0
TLS3_k127_7114579_0 ABC transporter - - - 9.362e-233 745.0
TLS3_k127_7114579_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 339.0
TLS3_k127_7114579_2 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003039 269.0
TLS3_k127_7122333_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 579.0
TLS3_k127_7147943_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 407.0
TLS3_k127_7147943_1 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 357.0
TLS3_k127_7147943_2 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005207 271.0
TLS3_k127_7147943_3 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001724 244.0
TLS3_k127_7147943_4 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000009815 199.0
TLS3_k127_7147943_5 - - - - 0.000000000000007542 87.0
TLS3_k127_7151077_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 1.641e-195 617.0
TLS3_k127_7151077_1 Mn2 and Fe2 transporters of the NRAMP family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002994 283.0
TLS3_k127_7164840_0 ABC transporter K16907 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0015562,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 314.0
TLS3_k127_7164840_1 Transcriptional regulator - - - 0.00000000000000000000007977 108.0
TLS3_k127_7164840_2 ATPase, P-type transporting, HAD superfamily, subfamily IC - - - 0.000004751 59.0
TLS3_k127_7174594_0 Belongs to the MurCDEF family K01924 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007984 501.0
TLS3_k127_7199935_0 Belongs to the aldehyde dehydrogenase family K22187 - - 6.824e-249 778.0
TLS3_k127_7199935_1 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 306.0
TLS3_k127_7199935_2 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005655 250.0
TLS3_k127_7200594_0 Fe-S oxidoreductase - - - 7.869e-231 736.0
TLS3_k127_7200594_1 aldo keto reductase K00064 - 1.1.1.122 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 383.0
TLS3_k127_7200594_2 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 306.0
TLS3_k127_7200594_3 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 300.0
TLS3_k127_7200594_4 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000001325 196.0
TLS3_k127_7200594_5 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.000000000000000000000000000000000000000000000001776 181.0
TLS3_k127_7200594_6 pyridoxamine 5-phosphate - - - 0.00000000000000000000000000009144 122.0
TLS3_k127_7200594_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000003174 106.0
TLS3_k127_7200594_8 mandelate racemase muconate lactonizing K18334 - 4.2.1.68 0.000000004149 59.0
TLS3_k127_721119_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into K01875 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 405.0
TLS3_k127_721119_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 360.0
TLS3_k127_721119_2 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001276 268.0
TLS3_k127_721119_3 YibE F family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001105 267.0
TLS3_k127_721119_4 Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000003274 257.0
TLS3_k127_721119_5 PFAM ROK family protein K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000003844 249.0
TLS3_k127_721119_6 PFAM Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000006743 168.0
TLS3_k127_721119_7 Secreted repeat of unknown function - - - 0.00000000000000000000000000000004393 134.0
TLS3_k127_721119_8 Transglycosylase associated protein - - - 0.000000000000000000000000000000266 124.0
TLS3_k127_721119_9 Protein of unknown function (DUF4446) - - - 0.000000000000000000003896 101.0
TLS3_k127_721277_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 450.0
TLS3_k127_721277_1 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000001702 139.0
TLS3_k127_721277_2 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.000000000000000000548 98.0
TLS3_k127_721277_3 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000001707 76.0
TLS3_k127_7214476_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 539.0
TLS3_k127_7214476_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 340.0
TLS3_k127_7214476_10 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.000008092 57.0
TLS3_k127_7214476_2 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002208 269.0
TLS3_k127_7214476_3 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000001006 258.0
TLS3_k127_7214476_4 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000772 205.0
TLS3_k127_7214476_5 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000122 188.0
TLS3_k127_7214476_6 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000004323 181.0
TLS3_k127_7214476_7 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.00000000000000000000000000000000000000001411 163.0
TLS3_k127_7214476_8 Stress responsive A/B Barrel Domain - - - 0.00000000006143 70.0
TLS3_k127_7214476_9 OsmC-like protein - - - 0.000007211 52.0
TLS3_k127_7218751_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 581.0
TLS3_k127_7218751_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000002664 228.0
TLS3_k127_7218751_3 a CheY-like receiver domain and - - - 0.000000000000000000000000000000000000000000009443 164.0
TLS3_k127_7218751_4 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000007668 172.0
TLS3_k127_7237922_0 Lamin Tail Domain K07004 - - 6.295e-251 805.0
TLS3_k127_7237922_1 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 533.0
TLS3_k127_7237922_2 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 477.0
TLS3_k127_7237922_3 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000009121 189.0
TLS3_k127_7245443_0 PAS domain K18350 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000001249 249.0
TLS3_k127_7245443_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000000000000001638 192.0
TLS3_k127_7245443_2 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000008317 76.0
TLS3_k127_7252566_0 COG0433 Predicted ATPase K06915 - - 5.848e-226 723.0
TLS3_k127_7252566_1 Sulfurtransferase K01011 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 453.0
TLS3_k127_7252566_2 SufE protein probably involved in Fe-S center assembly K02426 - - 0.0000000000000000000000000000000000000000001211 163.0
TLS3_k127_7252566_3 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.0000000000000000000004936 101.0
TLS3_k127_7297432_0 Glycine cleavage system P-protein K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 571.0
TLS3_k127_7297432_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 372.0
TLS3_k127_7297432_2 Bifunctional nuclease K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000002218 183.0
TLS3_k127_7297432_3 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000004116 182.0
TLS3_k127_7304409_0 Bacterial periplasmic substrate-binding proteins K02030,K02424,K17073 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009746 261.0
TLS3_k127_7304409_1 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000002478 228.0
TLS3_k127_7304409_2 - - - - 0.0000000000000000000000000000000000000000000005597 170.0
TLS3_k127_7304409_3 FR47-like protein - - - 0.000000000000000000000001607 113.0
TLS3_k127_7304409_4 Uncharacterized protein family UPF0016 - - - 0.0000000000635 76.0
TLS3_k127_7320100_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008638 336.0
TLS3_k127_7320100_1 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.0000000000000000000000000000000000001284 160.0
TLS3_k127_7320100_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000003025 132.0
TLS3_k127_7320100_3 Cobalamin B12-binding domain protein - - - 0.000000000000000000000000000004366 130.0
TLS3_k127_7334348_0 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 299.0
TLS3_k127_7334348_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000007724 265.0
TLS3_k127_7334348_2 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000001104 246.0
TLS3_k127_7339394_0 potassium ion transmembrane transporter activity K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 7.445e-222 705.0
TLS3_k127_7339394_1 PFAM von Willebrand factor type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 369.0
TLS3_k127_7339394_2 COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 345.0
TLS3_k127_7339394_3 Protein of unknown function (DUF3097) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 321.0
TLS3_k127_7339394_4 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 314.0
TLS3_k127_7339394_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000001546 245.0
TLS3_k127_7339394_6 PASTA K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000001693 225.0
TLS3_k127_7339394_7 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000000000000000000000000000000000000000000007609 205.0
TLS3_k127_7339394_8 YjbR - - - 0.00000000000000000000000000000000000000000009073 164.0
TLS3_k127_7357216_0 ABC transporter - - - 0.0 1414.0
TLS3_k127_7357216_1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 584.0
TLS3_k127_7357216_10 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000006223 230.0
TLS3_k127_7357216_11 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000158 181.0
TLS3_k127_7357216_12 Pfam:Methyltransf_6 - - - 0.000000000000000000000000000000000000000000000009969 179.0
TLS3_k127_7357216_13 Iron-sulfur cluster assembly protein - - - 0.000000000000000000028 100.0
TLS3_k127_7357216_14 Cupin domain - - - 0.000000000000000001543 97.0
TLS3_k127_7357216_15 - - - - 0.0001958 47.0
TLS3_k127_7357216_2 Creatinase/Prolidase N-terminal domain K01271,K15783 - 3.4.13.9,3.5.4.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 580.0
TLS3_k127_7357216_3 amidohydrolase 2 K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 569.0
TLS3_k127_7357216_4 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 418.0
TLS3_k127_7357216_5 Oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 388.0
TLS3_k127_7357216_6 PAC sensor-containing diguanylate cyclase phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 334.0
TLS3_k127_7357216_7 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 307.0
TLS3_k127_7357216_8 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000008676 228.0
TLS3_k127_7357216_9 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001536 229.0
TLS3_k127_7358713_0 Serine phosphatase RsbU, regulator of sigma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 432.0
TLS3_k127_7358713_1 PFAM Pyruvate carboxyltransferase K01640,K18314 - 4.1.3.4,4.1.3.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 400.0
TLS3_k127_7358713_2 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 381.0
TLS3_k127_7358713_3 Protein of unknown function (DUF454) K09790 - - 0.0000000000000000000000000000000000000000000001262 172.0
TLS3_k127_7358713_4 Lamin Tail Domain - - - 0.0000000000000000000000000614 112.0
TLS3_k127_7358713_5 Transcriptional regulator - - - 0.000000000000000000537 98.0
TLS3_k127_7358713_6 Domain of unknown function (DUF4349) - - - 0.00000000000000001493 94.0
TLS3_k127_7358713_7 DoxX family - - - 0.000000111 59.0
TLS3_k127_7368306_0 PFAM amidohydrolase 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 317.0
TLS3_k127_7368306_1 Major facilitator Superfamily - - - 0.000000000000000000008461 99.0
TLS3_k127_7372561_0 Peptidase C26 K01658,K01664 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000001104 244.0
TLS3_k127_7372561_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000002314 100.0
TLS3_k127_7373924_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 369.0
TLS3_k127_7373924_1 Signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001694 251.0
TLS3_k127_7373924_2 regulatory protein GntR HTH K03710 - - 0.0000000000000000000000000000000000000000000000000000000000001321 222.0
TLS3_k127_7373924_3 phosphonoacetaldehyde hydrolase activity K19270 - 3.1.3.23 0.000000000000000000000000000000000000000000000000005793 189.0
TLS3_k127_7373924_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000002514 158.0
TLS3_k127_7373924_5 GGDEF domain - - - 0.00000000000000000000000000000000573 134.0
TLS3_k127_7373924_6 phosphotransferase system K02803 - 2.7.1.193 0.00000000000000000002445 95.0
TLS3_k127_7375082_0 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007782 437.0
TLS3_k127_7375082_1 PRC-barrel domain - - - 0.000000000000000000000000000000000000000000253 176.0
TLS3_k127_7375082_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000026 86.0
TLS3_k127_7375082_3 PRC-barrel domain - - - 0.0000000000000001711 92.0
TLS3_k127_7382638_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1469.0
TLS3_k127_7382638_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1172.0
TLS3_k127_7382638_2 Belongs to the GPI family K01810 - 5.3.1.9 3.425e-196 670.0
TLS3_k127_7382638_3 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009742 343.0
TLS3_k127_7382638_4 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000006257 222.0
TLS3_k127_7382638_5 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000000000000000000000003859 196.0
TLS3_k127_7382638_6 menaquinone-dependent protoporphyrinogen oxidase activity K00230 - 1.3.5.3 0.000000000000000000000000000000000000000000002972 177.0
TLS3_k127_7382638_7 Belongs to the universal stress protein A family - - - 0.00000000000000000000002039 111.0
TLS3_k127_7392012_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 335.0
TLS3_k127_7392012_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000003645 241.0
TLS3_k127_7392012_2 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding - - - 0.0000000000000000000000000000000000000000000006359 174.0
TLS3_k127_7392012_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000005543 164.0
TLS3_k127_7396793_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 519.0
TLS3_k127_7396793_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000315 235.0
TLS3_k127_7397579_0 Acyl-CoA oxidase K00232 - 1.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 445.0
TLS3_k127_7397579_1 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 336.0
TLS3_k127_7397579_2 Transcriptional regulator - - - 0.000000000000000000000000000000009803 136.0
TLS3_k127_7406308_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 371.0
TLS3_k127_7406308_1 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 - 1.6.5.3 0.00002377 55.0
TLS3_k127_7407932_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 553.0
TLS3_k127_7407932_1 Secreted repeat of unknown function - - - 0.000000000000000000000000000000000000000000000000002831 205.0
TLS3_k127_7407932_2 peptidase C60 sortase A and B - - - 0.00000000000000000000000000000000000000000000007316 177.0
TLS3_k127_7407932_3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K08641,K11206 - 3.4.13.22 0.00000000000000000000000000000000000000000007873 173.0
TLS3_k127_7407932_4 - - - - 0.0000000000000000000000000000000000000000001455 178.0
TLS3_k127_7407932_5 - - - - 0.000000000000000000000002501 111.0
TLS3_k127_7407932_6 Immunoglobulin-like domain of bacterial spore germination - - - 0.000000000000000002955 91.0
TLS3_k127_7407932_7 Secreted repeat of unknown function - - - 0.000000000000001322 91.0
TLS3_k127_7407932_8 Endonuclease Exonuclease phosphatase - - - 0.000000003555 64.0
TLS3_k127_7407932_9 bis(5'-adenosyl)-triphosphatase activity K02503 - - 0.0002814 53.0
TLS3_k127_7410200_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 8.233e-216 695.0
TLS3_k127_7410200_1 Belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007953 601.0
TLS3_k127_7410200_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 312.0
TLS3_k127_7414357_0 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 403.0
TLS3_k127_7414357_1 Universal stress protein - - - 0.0000000000000000000000000000009027 133.0
TLS3_k127_7414357_2 Regulatory protein - - - 0.0000000000003655 72.0
TLS3_k127_742036_0 Bacterial extracellular solute-binding protein K02027,K17329 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 320.0
TLS3_k127_742036_1 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001183 281.0
TLS3_k127_742036_2 COG1874 Beta-galactosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008725 268.0
TLS3_k127_742036_3 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003098 261.0
TLS3_k127_742036_4 UTRA K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000005412 231.0
TLS3_k127_742036_5 BadF BadG BcrA BcrD - - - 0.000000000000000000000000000000000000000006108 175.0
TLS3_k127_742036_6 PFAM WD domain, G-beta repeat - - - 0.000000000000006561 83.0
TLS3_k127_742036_7 V-set and transmembrane domain-containing protein 2B - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944 - 0.0001545 47.0
TLS3_k127_7432828_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 GO:0008150,GO:0040007 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 308.0
TLS3_k127_7432828_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000004097 176.0
TLS3_k127_7432828_2 precorrin-2 dehydrogenase activity K02302,K02304 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000007645 75.0
TLS3_k127_7433531_0 DNA polymerase K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 306.0
TLS3_k127_7446476_0 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 625.0
TLS3_k127_7446476_1 Signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005667 451.0
TLS3_k127_7446476_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001699 274.0
TLS3_k127_7446476_3 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002049 252.0
TLS3_k127_7446476_5 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000004537 104.0
TLS3_k127_7446476_6 haloacid dehalogenase-like hydrolase - - - 0.000000000005865 77.0
TLS3_k127_7446476_7 LysE type translocator - - - 0.00000000001767 74.0
TLS3_k127_7446669_0 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 533.0
TLS3_k127_7446669_1 Sulfate permease family K03321 GO:0000103,GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006790,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008152,GO:0008272,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0017076,GO:0019001,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0097159,GO:0098656,GO:0098660,GO:0098661,GO:1901265,GO:1901363,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 494.0
TLS3_k127_7446669_2 PFAM Rhodanese domain protein - - - 0.0000000000000000000000000000000000000000000000000006589 190.0
TLS3_k127_7464419_0 Pfam Sodium hydrogen exchanger K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007415 384.0
TLS3_k127_7464419_1 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 301.0
TLS3_k127_7464419_2 methylglyoxal synthase activity K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.0000000000000000000000000000000000000000000000000000000003131 205.0
TLS3_k127_7464419_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000001077 93.0
TLS3_k127_7464419_4 Ferredoxin - - - 0.000000000000000004791 88.0
TLS3_k127_7464419_5 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000002232 55.0
TLS3_k127_7490902_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 1.339e-253 794.0
TLS3_k127_7490902_1 nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein K00366,K00392 GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016002,GO:0016053,GO:0016491,GO:0016667,GO:0016673,GO:0019344,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050311,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.7.7.1,1.8.7.1 4.409e-197 631.0
TLS3_k127_7490902_2 Belongs to the class-I aminoacyl-tRNA synthetase family K15526 - 6.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 371.0
TLS3_k127_7490902_3 A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics K18455 GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010126,GO:0010127,GO:0016137,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0071704,GO:0098754,GO:1901135,GO:1901657 3.5.1.115 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 323.0
TLS3_k127_7490902_4 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 323.0
TLS3_k127_7490902_5 Belongs to the PAPS reductase family. CysH subfamily K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000003802 216.0
TLS3_k127_7490902_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000002523 201.0
TLS3_k127_7490902_7 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000009598 119.0
TLS3_k127_7490902_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000001763 107.0
TLS3_k127_7490902_9 rRNA binding - - - 0.00002987 56.0
TLS3_k127_7497915_0 MoeA domain protein domain I and II K00963,K03750 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1,2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 357.0
TLS3_k127_7497915_1 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 327.0
TLS3_k127_7497915_2 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 344.0
TLS3_k127_7497915_3 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 313.0
TLS3_k127_7497915_4 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002237 289.0
TLS3_k127_7497915_5 TIGRFAM molybdenum cofactor synthesis domain K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000004159 172.0
TLS3_k127_7497915_6 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000004349 162.0
TLS3_k127_7497915_7 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.000000000000000000000000000002161 133.0
TLS3_k127_7497915_8 regulatory protein, FmdB family - - - 0.00000000000000000006078 102.0
TLS3_k127_7497915_9 SAF - - - 0.0003837 51.0
TLS3_k127_7498253_0 Phage shock protein C (PspC) K03973 - - 0.000000000000000000000002169 110.0
TLS3_k127_7498253_1 PspC domain - - - 0.000002167 58.0
TLS3_k127_7498253_2 Protein of unknown function (DUF998) - - - 0.000006862 57.0
TLS3_k127_750460_0 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.000000000000000000000000000000000000000000000000000000000003466 218.0
TLS3_k127_750460_1 ATPase involved in DNA repair K03546 - - 0.0000000000000000000000000000000000000000000000000000000001861 212.0
TLS3_k127_7511916_0 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 519.0
TLS3_k127_7511916_1 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10562 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 458.0
TLS3_k127_7511916_2 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 409.0
TLS3_k127_7511916_3 Lysine exporter protein (Lyse ygga) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001726 284.0
TLS3_k127_7511916_4 short-chain dehydrogenase reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000001424 260.0
TLS3_k127_7511916_5 Methyltransferase domain - - - 0.00000000000000000000000000000000288 140.0
TLS3_k127_7557142_0 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 327.0
TLS3_k127_7557142_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.000000000000000001902 96.0
TLS3_k127_7565984_0 SMART alpha amylase catalytic sub domain K01187 - 3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 493.0
TLS3_k127_7565984_1 CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 418.0
TLS3_k127_7565984_2 overlaps another CDS with the same product name - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 362.0
TLS3_k127_7565984_3 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 340.0
TLS3_k127_7565984_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000339 270.0
TLS3_k127_7565984_5 PFAM YbaK prolyl-tRNA synthetase associated region - - - 0.000000000000000000000000000000004606 138.0
TLS3_k127_7565984_6 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures - - - 0.0000000000000000000000000488 119.0
TLS3_k127_7565984_7 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000001997 78.0
TLS3_k127_7565984_8 Protein of unknown function (DUF1232) - - - 0.00004244 52.0
TLS3_k127_7584941_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1152.0
TLS3_k127_7584941_1 carbon monoxide dehydrogenase subunit G K09386 - - 0.00000000000000000000000000003324 129.0
TLS3_k127_7587650_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 1.353e-211 677.0
TLS3_k127_7587650_1 Penicillin binding protein transpeptidase domain K05364 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 467.0
TLS3_k127_7587650_2 Belongs to the SEDS family K03588 GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 401.0
TLS3_k127_7587650_3 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 395.0
TLS3_k127_7587650_4 Serine/threonine phosphatases, family 2C, catalytic domain K20074 GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000003481 232.0
TLS3_k127_7587650_5 Domain of unknown function (DUF4191) - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000006447 169.0
TLS3_k127_7587650_6 Protein of unknown function (DUF2662) - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000001627 151.0
TLS3_k127_7587650_7 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding - - - 0.000000000000000000000000000212 123.0
TLS3_k127_7587650_8 FHA domain containing protein - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - 0.000000000000000000002156 102.0
TLS3_k127_7602149_0 lipolytic protein G-D-S-L family - - - 0.0 1038.0
TLS3_k127_7602149_1 protein conserved in bacteria K09955 - - 1.489e-249 796.0
TLS3_k127_7602149_2 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 571.0
TLS3_k127_7602149_3 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 505.0
TLS3_k127_7602149_4 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 401.0
TLS3_k127_7602149_5 PFAM binding-protein-dependent transport systems inner membrane component K02025,K10189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 420.0
TLS3_k127_7624755_0 Aconitase C-terminal domain K01681 - 4.2.1.3 9.21e-305 946.0
TLS3_k127_7624755_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 347.0
TLS3_k127_7624755_10 PFAM peptidase - - - 0.0000000000000000000000000004258 123.0
TLS3_k127_7624755_11 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000008374 87.0
TLS3_k127_7624755_12 PFAM magnesium chelatase ChlI subunit K07391 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.00000000004596 70.0
TLS3_k127_7624755_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 317.0
TLS3_k127_7624755_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 302.0
TLS3_k127_7624755_4 Sigma-70, region 4 K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001216 270.0
TLS3_k127_7624755_5 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000005955 246.0
TLS3_k127_7624755_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000003392 218.0
TLS3_k127_7624755_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000001628 206.0
TLS3_k127_7624755_8 Cytidylyltransferase family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.00000000000000000000000000000000000000000000000000001886 202.0
TLS3_k127_7624755_9 DNA processing protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000001546 196.0
TLS3_k127_7626132_0 sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 395.0
TLS3_k127_7626132_1 Bacterial sugar transferase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000003457 245.0
TLS3_k127_7626132_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000005773 100.0
TLS3_k127_7626132_3 Bacterial protein of unknown function (DUF948) - - - 0.00000001469 62.0
TLS3_k127_7626132_4 helix_turn_helix, Lux Regulon K07684 - - 0.0000003909 60.0
TLS3_k127_7626132_5 - - - - 0.0003695 46.0
TLS3_k127_7641319_0 glutamate synthase, alpha subunit domain protein K00284 - 1.4.7.1 0.0 1393.0
TLS3_k127_7641319_1 ABC transporter, transmembrane region K06147 - - 7.415e-196 632.0
TLS3_k127_7641319_2 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009463 248.0
TLS3_k127_7642102_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002277 291.0
TLS3_k127_7642102_1 Glycosyl transferase, family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000001635 207.0
TLS3_k127_7644874_0 Oxidoreductase family, C-terminal alpha beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 580.0
TLS3_k127_7644874_1 AP endonuclease family 2 C terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 352.0
TLS3_k127_7648307_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335,K05587 - 1.6.5.3 5.167e-212 682.0
TLS3_k127_7648307_1 Coenzyme F420-reducing hydrogenase, alpha subunit K00436 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 610.0
TLS3_k127_7648307_2 PFAM 2Fe-2S iron-sulfur cluster binding domain K05588 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 338.0
TLS3_k127_7648307_3 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000001564 241.0
TLS3_k127_7648307_4 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K05586 - 1.6.5.3 0.00000000000000000000000000000000000000000000244 176.0
TLS3_k127_7648307_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000009731 119.0
TLS3_k127_7648307_6 Initiates the rapid degradation of small, acid-soluble proteins during spore germination - - - 0.0000000000000000007486 102.0
TLS3_k127_7648307_7 Tellurite resistance protein TerB - - - 0.000000000005467 70.0
TLS3_k127_7659521_0 PFAM binding-protein-dependent transport systems inner membrane component K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009149 289.0
TLS3_k127_7659521_1 Binding-protein-dependent transport system inner membrane component K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006234 277.0
TLS3_k127_7659521_2 Bacterial extracellular solute-binding protein K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003355 260.0
TLS3_k127_7659521_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000001871 210.0
TLS3_k127_7660177_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 1.489e-256 797.0
TLS3_k127_7660177_1 spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 460.0
TLS3_k127_7660177_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 437.0
TLS3_k127_7660177_3 Aldehyde dehydrogenase K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 407.0
TLS3_k127_7660177_4 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 329.0
TLS3_k127_7660177_5 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000009719 258.0
TLS3_k127_7660177_6 Uncharacterized protein conserved in bacteria (DUF2332) - - - 0.000000000000000000000000000000000000000000000000000000000000001364 233.0
TLS3_k127_7660177_7 Low molecular weight phosphatase family - - - 0.00000000000000000000000000000000000000000000000000001097 199.0
TLS3_k127_7660177_8 transcriptional regulator K03892 - - 0.000000000000000000000000000000000000000001268 159.0
TLS3_k127_7673111_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.0 1082.0
TLS3_k127_7673111_1 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 542.0
TLS3_k127_7673111_10 Transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000005481 161.0
TLS3_k127_7673111_11 Pfam Zn-finger in ubiquitin-hydrolases and other protein - - - 0.00000000000000000000000000000000000000002327 154.0
TLS3_k127_7673111_12 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000002491 160.0
TLS3_k127_7673111_13 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000003435 109.0
TLS3_k127_7673111_14 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000002646 71.0
TLS3_k127_7673111_2 Cys/Met metabolism PLP-dependent enzyme K01739 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 514.0
TLS3_k127_7673111_3 trisaccharide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 380.0
TLS3_k127_7673111_4 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005171 287.0
TLS3_k127_7673111_5 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003982 265.0
TLS3_k127_7673111_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000005022 244.0
TLS3_k127_7673111_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000002619 219.0
TLS3_k127_7673111_8 KR domain - - - 0.0000000000000000000000000000000000000000000001131 177.0
TLS3_k127_7673111_9 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000001736 165.0
TLS3_k127_7677754_0 pyridine nucleotide-disulphide oxidoreductase K17218 GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0005515,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0042802,GO:0044237,GO:0045333,GO:0055114 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 381.0
TLS3_k127_7677754_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 302.0
TLS3_k127_7677754_10 BON domain - - - 0.00000000000466 79.0
TLS3_k127_7677754_2 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003046 253.0
TLS3_k127_7677754_3 glyoxalase III activity - - - 0.00000000000000000000000000186 128.0
TLS3_k127_7677754_4 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000003305 115.0
TLS3_k127_7677754_5 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000003522 107.0
TLS3_k127_7677754_6 PFAM CBS domain containing protein K04767 - - 0.0000000000000000002404 93.0
TLS3_k127_7677754_7 Universal stress protein family - - - 0.00000000000000002562 95.0
TLS3_k127_7677754_8 BON domain - - - 0.0000000000000002263 92.0
TLS3_k127_7677754_9 Putative peptidoglycan binding domain - - - 0.000000000001514 79.0
TLS3_k127_7692019_0 Phosphotransferase System K02768,K02769,K02770 - 2.7.1.202 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 445.0
TLS3_k127_7692019_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 430.0
TLS3_k127_7692019_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 376.0
TLS3_k127_7692019_3 PFAM cation transporter K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 379.0
TLS3_k127_7692019_4 potassium uptake protein TrkH K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 363.0
TLS3_k127_7692019_5 domain protein K03499 - - 0.000000000000000000000000000000000000002113 168.0
TLS3_k127_7692019_6 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000001701 154.0
TLS3_k127_7692019_7 PTS HPr component phosphorylation site K11189 - - 0.000000000000000148 83.0
TLS3_k127_7692019_8 - - - - 0.000001487 60.0
TLS3_k127_7692019_9 - - - - 0.0007079 51.0
TLS3_k127_7694981_0 Protein of unknown function (DUF1116) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 585.0
TLS3_k127_7694981_1 CoA-ligase K02381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 480.0
TLS3_k127_7694981_2 Transcriptional regulatory protein, C terminal K11329 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 315.0
TLS3_k127_7694981_3 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000007721 145.0
TLS3_k127_7694981_4 Protein of unknown function (DUF2877) - - - 0.00000000000000000000000007531 122.0
TLS3_k127_7696600_0 Glycosyl hydrolases family 6 K19668 - 3.2.1.91 4.588e-209 663.0
TLS3_k127_7696600_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 527.0
TLS3_k127_7696600_2 Belongs to the aldehyde dehydrogenase family K00135 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009013,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 513.0
TLS3_k127_7696600_3 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 402.0
TLS3_k127_7696600_4 TIGRFAM daunorubicin resistance ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 372.0
TLS3_k127_7696600_5 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003448 266.0
TLS3_k127_7696600_6 DNA primase, small subunit - - - 0.00000000000000000000000000000000000000000000000000000004234 208.0
TLS3_k127_7696600_7 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000008028 195.0
TLS3_k127_7696600_8 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000008984 96.0
TLS3_k127_770100_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 5.741e-202 647.0
TLS3_k127_770100_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 568.0
TLS3_k127_770100_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 499.0
TLS3_k127_770100_3 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 347.0
TLS3_k127_770100_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 315.0
TLS3_k127_770100_5 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000005238 224.0
TLS3_k127_770100_6 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000009225 67.0
TLS3_k127_770100_7 - - - - 0.000001829 59.0
TLS3_k127_7701582_0 Putative metal-binding motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 327.0
TLS3_k127_7711056_0 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 339.0
TLS3_k127_7711056_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 339.0
TLS3_k127_7711056_2 pilus organization - - - 0.0000000000000000146 91.0
TLS3_k127_7732690_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 2.549e-290 903.0
TLS3_k127_7732690_1 transporter K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 632.0
TLS3_k127_7732690_2 NADPH quinone reductase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007648 373.0
TLS3_k127_7732690_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000005664 204.0
TLS3_k127_7732690_4 Phosphatase K20074 GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 3.1.3.16 0.000000000000000000000000000000000000000000000000004645 190.0
TLS3_k127_7752140_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 4.709e-298 949.0
TLS3_k127_7752140_1 ATP-grasp domain K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 432.0
TLS3_k127_7752140_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 309.0
TLS3_k127_7752140_3 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000001711 215.0
TLS3_k127_7752140_4 with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000002225 175.0
TLS3_k127_7752140_5 HD domain - - - 0.000000000000000008693 97.0
TLS3_k127_7752140_6 response regulator - - - 0.00000003724 63.0
TLS3_k127_7752884_0 arylformamidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 359.0
TLS3_k127_7752884_1 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000001001 154.0
TLS3_k127_7752884_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01856,K01860,K19802 - 5.1.1.20,5.5.1.1,5.5.1.7 0.0000000000000000000000000003061 126.0
TLS3_k127_7752884_3 Cupin domain - - - 0.000000000000000000000000321 111.0
TLS3_k127_7752884_4 Antibiotic biosynthesis monooxygenase - GO:0003674,GO:0003824 - 0.000000000000000001623 97.0
TLS3_k127_7758632_0 Stage II sporulation E family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 427.0
TLS3_k127_7758632_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007677 385.0
TLS3_k127_7758632_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002013 280.0
TLS3_k127_7758632_3 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000419 248.0
TLS3_k127_7758632_4 - - - - 0.0000000000000000000000000000000000000000000000001545 180.0
TLS3_k127_7758632_5 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000392 160.0
TLS3_k127_7759522_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030312,GO:0030976,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 3.539e-232 733.0
TLS3_k127_7759522_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 544.0
TLS3_k127_7759522_2 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 363.0
TLS3_k127_7759522_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000004085 267.0
TLS3_k127_7759522_4 TIGRFAM Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000002592 234.0
TLS3_k127_7759522_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000001934 228.0
TLS3_k127_7759522_6 acetyltransferase - GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - 0.000000001191 58.0
TLS3_k127_7763493_0 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001337 243.0
TLS3_k127_7763493_1 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000347 188.0
TLS3_k127_7772017_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 317.0
TLS3_k127_7772017_1 PFAM ROK family protein K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000003872 251.0
TLS3_k127_7772017_2 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000001549 209.0
TLS3_k127_7772017_3 Cyclase dehydrase - - - 0.000000000000000000000000000006673 124.0
TLS3_k127_7772017_4 translation release factor activity K03265 - - 0.0000000000000000000000000009286 126.0
TLS3_k127_7772017_5 PTS system fructose IIA component K05881 - 2.7.1.121 0.0000000000000008637 82.0
TLS3_k127_7773194_0 Glycosyltransferase family 28 C-terminal domain - - - 2.041e-279 870.0
TLS3_k127_7773194_1 NnrU protein K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 356.0
TLS3_k127_7773194_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 288.0
TLS3_k127_7780963_0 LAGLIDADG DNA endonuclease family K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 4.578e-296 924.0
TLS3_k127_7780963_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 516.0
TLS3_k127_7780963_10 Helix-turn-helix domain - - - 0.0000000000001428 81.0
TLS3_k127_7780963_11 ferrous iron binding - - - 0.00000004015 64.0
TLS3_k127_7780963_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 372.0
TLS3_k127_7780963_3 Belongs to the CinA family K03742,K03743 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 305.0
TLS3_k127_7780963_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000006199 259.0
TLS3_k127_7780963_5 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000006748 234.0
TLS3_k127_7780963_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000006905 218.0
TLS3_k127_7780963_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000002438 141.0
TLS3_k127_7780963_8 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000005951 113.0
TLS3_k127_7780963_9 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000004069 102.0
TLS3_k127_7784948_0 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 503.0
TLS3_k127_7784948_1 PFAM Phospholipid glycerol acyltransferase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 385.0
TLS3_k127_7784948_2 PFAM NAD-dependent epimerase dehydratase K01784 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 329.0
TLS3_k127_7784948_3 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 318.0
TLS3_k127_7800180_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 383.0
TLS3_k127_7800180_1 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000232 122.0
TLS3_k127_7800180_2 Cold shock protein K03704 - - 0.00000000000000000000000000575 111.0
TLS3_k127_7804906_0 DeoR C terminal sensor domain K03436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 298.0
TLS3_k127_7804906_1 Belongs to the carbohydrate kinase PfkB family K00882 - 2.7.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007161 283.0
TLS3_k127_7804906_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000102 220.0
TLS3_k127_7804906_3 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.000000000000000000000000000000000000000008639 158.0
TLS3_k127_7804906_4 PTS system, Lactose/Cellobiose specific IIB subunit K02768,K02769,K02770 - 2.7.1.202 0.000000000000000000000000002863 121.0
TLS3_k127_7804978_0 UPF0060 membrane protein K09771 GO:0005575,GO:0005576 - 0.00000000000000000000000000000000000000000000000000000001564 205.0
TLS3_k127_7804978_1 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000001132 183.0
TLS3_k127_7804978_2 Transcriptional regulator K19591 - - 0.00000000000000001095 87.0
TLS3_k127_7804978_3 - - - - 0.0002146 49.0
TLS3_k127_7813395_0 2-oxoglutarate dehydrogenase C-terminal K00164 - 1.2.4.2 0.0 1316.0
TLS3_k127_7813395_1 Aminopeptidase I zinc metalloprotease (M18) K01267 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 488.0
TLS3_k127_7813395_2 AI-2E family transporter K20469 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000968 238.0
TLS3_k127_7813395_3 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.000000000000000000000000000000003292 139.0
TLS3_k127_7813395_4 Biotin-lipoyl like K02160 - - 0.00000000009225 67.0
TLS3_k127_7813395_5 RDD family - - - 0.0000001012 64.0
TLS3_k127_7818519_0 Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway K15521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044249,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 2.4.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 337.0
TLS3_k127_7818519_1 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000000000001727 143.0
TLS3_k127_7818519_2 Putative bacterial sensory transduction regulator - - - 0.00000000000000000000000004311 118.0
TLS3_k127_7821208_0 Transcriptional regulatory protein, C terminal K07669,K07672 GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 304.0
TLS3_k127_7821208_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 311.0
TLS3_k127_7824099_0 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K05342 - 2.4.1.64 1.012e-302 947.0
TLS3_k127_7824099_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K21789 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 525.0
TLS3_k127_7824099_2 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 424.0
TLS3_k127_7824099_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 362.0
TLS3_k127_7824099_4 phosphonoacetaldehyde hydrolase activity K01087,K01194,K01838,K05342 GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008801,GO:0009058,GO:0009292,GO:0009294,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016853,GO:0016866,GO:0016868,GO:0019203,GO:0030312,GO:0033554,GO:0034637,GO:0040007,GO:0042221,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046351,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0071704,GO:0071944,GO:1901576 2.4.1.64,3.1.3.12,3.2.1.28,5.4.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 294.0
TLS3_k127_7824099_5 Inositol monophosphatase family K01092,K05602 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008934,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016053,GO:0016137,GO:0016138,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052745,GO:0052803,GO:0052834,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659 3.1.3.15,3.1.3.25 0.000000000000000000000000000000000000000000000000000003084 202.0
TLS3_k127_7824099_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000001924 54.0
TLS3_k127_782683_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 482.0
TLS3_k127_782683_1 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009816 442.0
TLS3_k127_782683_10 SCP-2 sterol transfer family - - - 0.000007423 55.0
TLS3_k127_782683_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 401.0
TLS3_k127_782683_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 399.0
TLS3_k127_782683_4 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 393.0
TLS3_k127_782683_5 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 366.0
TLS3_k127_782683_6 Glycosyl transferase WecB/TagA/CpsF family K05946 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000000009484 217.0
TLS3_k127_782683_7 sugar transferase - - - 0.0000000000000000000000000000000000000000000000005285 188.0
TLS3_k127_782683_8 Capsular exopolysaccharide family K08253 - 2.7.10.2 0.000000000000000000000000000000002184 149.0
TLS3_k127_782683_9 Stage II sporulation - - - 0.00000000000000000000000000008791 134.0
TLS3_k127_7838540_0 DNA primase, small subunit K01971 - 6.5.1.1 3.256e-199 668.0
TLS3_k127_7838540_1 ERCC4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 298.0
TLS3_k127_7838540_2 Peptidase family S51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000167 246.0
TLS3_k127_7838540_3 serine threonine protein kinase K08884 - 2.7.11.1 0.000000000000000000000001935 117.0
TLS3_k127_7838540_4 - - - - 0.000000000000001957 81.0
TLS3_k127_7838540_5 phosphoribosyl-ATP diphosphatase activity - - - 0.000000000003094 79.0
TLS3_k127_7841665_0 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 419.0
TLS3_k127_7841665_1 Transcriptional regulator - - - 0.0000000000000004062 82.0
TLS3_k127_7853557_0 Transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000008679 190.0
TLS3_k127_7853557_1 FAD-binding domain - - - 0.00000000000000000000000000000000000000000000001433 189.0
TLS3_k127_7876073_0 Amb_all K01728 - 4.2.2.2 1.157e-205 657.0
TLS3_k127_7876073_1 Belongs to the glycosyl hydrolase family 6 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 402.0
TLS3_k127_7877210_0 protein, coenzyme F420 biosynthesis associated - - - 0.000000000000000000000000000000000000000000000000000000000000000152 235.0
TLS3_k127_7901904_0 Cell envelope-related transcriptional attenuator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 325.0
TLS3_k127_7901904_1 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 322.0
TLS3_k127_7901904_2 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 306.0
TLS3_k127_7901904_3 RNA polymerase sigma-24 subunit, ECF subfamily - - - 0.0000000000000000000000000000000000000000000001374 191.0
TLS3_k127_7961846_0 histidine kinase HAMP region domain protein K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 321.0
TLS3_k127_7961846_1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 315.0
TLS3_k127_7961846_2 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000000000000000001538 188.0
TLS3_k127_7961846_3 ABC transporter K02003 - - 0.000000000000000000000000000000000679 138.0
TLS3_k127_7961846_4 - - - - 0.000000000000000001552 93.0
TLS3_k127_7961846_5 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000001957 84.0
TLS3_k127_7968582_0 Molybdate ABC transporter K02017,K02018 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 307.0
TLS3_k127_7968582_1 Activator of hsp90 atpase 1 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001573 248.0
TLS3_k127_7968582_2 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 - 0.00000000000000000000000000000000000000000000000000000000002021 220.0
TLS3_k127_7968582_3 NAT, N-acetyltransferase, of N-acetylglutamate synthase K22478 - 2.3.1.1,2.7.2.8 0.000000000000000000000000000000000000000000000000000004786 205.0
TLS3_k127_7968582_4 TOBE domain - - - 0.0000000000000000000000000002194 119.0
TLS3_k127_7975253_0 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000005264 235.0
TLS3_k127_7975253_1 PFAM CHAD domain containing protein - - - 0.000000000000000000000000000000000000000000000000000005197 201.0
TLS3_k127_7993560_0 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 459.0
TLS3_k127_7993560_1 PFAM EAL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001409 269.0
TLS3_k127_7993560_2 helix_turn_helix, mercury resistance - - - 0.000000000000002441 88.0
TLS3_k127_8006550_0 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 477.0
TLS3_k127_8006550_1 Belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 319.0
TLS3_k127_8006550_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001191 268.0
TLS3_k127_8006550_3 PFAM Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000002621 227.0
TLS3_k127_8006550_4 PFAM UbiA prenyltransferase K09833 GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009987,GO:0010189,GO:0018130,GO:0042360,GO:0042362,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617 2.5.1.115,2.5.1.116 0.0000000000000000000000000000000000000000000000000000000000006967 222.0
TLS3_k127_8006550_5 Domain of unknown function (DUF1772) - - - 0.000000000000000000000000000000000000000000000002759 178.0
TLS3_k127_8006550_6 ANTAR domain protein - - - 0.00000000000000000000000000000000000000003468 163.0
TLS3_k127_8006550_7 nucleotidyltransferase activity K07075 - - 0.00000000000000000000000000006206 123.0
TLS3_k127_8006550_8 Protein of unknown function DUF86 - - - 0.000000000000000000001196 103.0
TLS3_k127_8031219_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004528 237.0
TLS3_k127_8031219_1 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000008264 230.0
TLS3_k127_8031561_0 Transcriptional regulator - - - 1.317e-212 679.0
TLS3_k127_8031561_1 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 397.0
TLS3_k127_8031561_2 Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme. - - - 0.0000000000000000000000000000000000000000000000000000000000000001093 243.0
TLS3_k127_8039443_0 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 424.0
TLS3_k127_8039443_1 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000006184 212.0
TLS3_k127_8050670_0 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 325.0
TLS3_k127_8070538_0 - - - - 0.0000000000000000000000000000000000000000000000004501 193.0
TLS3_k127_8070538_1 beta-glucosidase K05350 - 3.2.1.21 0.00000000062 64.0
TLS3_k127_8074349_0 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000002353 245.0
TLS3_k127_8074349_1 Sensory domain in DIguanylate Cyclases and Two-component system - - - 0.0000000000000000000001539 98.0
TLS3_k127_8076016_0 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 467.0
TLS3_k127_8076016_1 Flotillin K07192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009734 354.0
TLS3_k127_8076016_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000005594 236.0
TLS3_k127_8076016_3 helix_turn_helix ASNC type K03718 - - 0.0000000000000000000000000000000000000000000000000000000002507 208.0
TLS3_k127_8076016_4 COGs COG2151 metal-sulfur cluster biosynthetic protein - - - 0.00000000000000000000000000002865 121.0
TLS3_k127_8076016_5 - - - - 0.0000000000000000000000002459 112.0
TLS3_k127_8076016_6 rhodanese-like PpiC domain-containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0009719,GO:0009725,GO:0009735,GO:0010033,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - 0.000001086 50.0
TLS3_k127_8079778_0 Basic membrane lipoprotein K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 450.0
TLS3_k127_8079778_1 Pyruvate kinase, barrel domain K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 400.0
TLS3_k127_8079778_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 366.0
TLS3_k127_8091626_0 Aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 385.0
TLS3_k127_8091626_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 379.0
TLS3_k127_8091626_2 Pyridoxal-phosphate dependent enzyme K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 351.0
TLS3_k127_8091626_3 ThiS family K03636 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000001835 128.0
TLS3_k127_8091626_4 Mov34 MPN PAD-1 family K21140 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016787,GO:0019344,GO:0019538,GO:0019752,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.13.1.6 0.00000000000000000000000000002103 123.0
TLS3_k127_8097975_0 Von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 447.0
TLS3_k127_8097975_1 Phage shock protein A K03969 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000009758 243.0
TLS3_k127_8097975_2 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000005299 134.0
TLS3_k127_8097975_3 - - - - 0.000000000000000000000000002505 122.0
TLS3_k127_8113905_0 Glyco_18 K01183 - 3.2.1.14 8.3e-216 680.0
TLS3_k127_8113905_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 616.0
TLS3_k127_8113905_10 - - - - 0.0000000001862 72.0
TLS3_k127_8113905_2 potassium uptake protein TrkH K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 393.0
TLS3_k127_8113905_3 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 373.0
TLS3_k127_8113905_4 response regulator, receiver K02483,K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 292.0
TLS3_k127_8113905_5 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008844 258.0
TLS3_k127_8113905_6 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000002583 261.0
TLS3_k127_8113905_7 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000008947 220.0
TLS3_k127_8113905_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000002216 200.0
TLS3_k127_8113905_9 Transglycosylase associated protein - - - 0.00000000000000000000002149 105.0
TLS3_k127_8117724_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0040007,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 9.319e-313 976.0
TLS3_k127_8117724_1 Belongs to the sigma-70 factor family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 614.0
TLS3_k127_8117724_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 402.0
TLS3_k127_8117724_3 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 357.0
TLS3_k127_8117724_4 YCII-related domain - - - 0.000000000000000000000000000000000000000000000005575 177.0
TLS3_k127_8117724_5 BetI-type transcriptional repressor, C-terminal - - - 0.0000000000000001096 90.0
TLS3_k127_8132078_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 9.923e-294 913.0
TLS3_k127_8132078_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 1.366e-211 671.0
TLS3_k127_8132078_10 membrane - - - 0.00000000000000000000000504 108.0
TLS3_k127_8132078_11 - - - - 0.0000000000002775 78.0
TLS3_k127_8132078_2 beta-galactosidase K12308 - 3.2.1.23 6.871e-208 656.0
TLS3_k127_8132078_3 Sodium:solute symporter family K14393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 566.0
TLS3_k127_8132078_4 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009098 537.0
TLS3_k127_8132078_5 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 437.0
TLS3_k127_8132078_6 Binding-protein-dependent transport system inner membrane component K02025,K10118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 404.0
TLS3_k127_8132078_7 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 383.0
TLS3_k127_8132078_8 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 329.0
TLS3_k127_8132078_9 Domain of unknown function (DUF4212) - - - 0.000000000000000000000000002799 119.0
TLS3_k127_8135494_0 amidohydrolase - - - 5.976e-198 626.0
TLS3_k127_8135494_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 490.0
TLS3_k127_8135494_10 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000002079 144.0
TLS3_k127_8135494_11 Endoribonuclease L-PSP - - - 0.000000000001821 79.0
TLS3_k127_8135494_12 of the drug metabolite transporter (DMT) superfamily - - - 0.00005533 55.0
TLS3_k127_8135494_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 410.0
TLS3_k127_8135494_3 2-hydroxy-3-oxopropionate reductase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 379.0
TLS3_k127_8135494_4 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 358.0
TLS3_k127_8135494_5 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 370.0
TLS3_k127_8135494_6 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 311.0
TLS3_k127_8135494_7 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 288.0
TLS3_k127_8135494_8 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000004406 240.0
TLS3_k127_8135494_9 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000005424 228.0
TLS3_k127_8143447_0 Transcriptional regulator - - - 0.0 1178.0
TLS3_k127_8143447_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000274 297.0
TLS3_k127_8143447_2 Histidine kinase - - - 0.00000000000000000000000000000000000005543 157.0
TLS3_k127_8143447_3 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000017 113.0
TLS3_k127_8146305_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.186e-202 657.0
TLS3_k127_8146305_1 IMP dehydrogenase / GMP reductase domain K00088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 378.0
TLS3_k127_8146305_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 346.0
TLS3_k127_8146305_3 DNA polymerase III, delta subunit K02341 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.00000000000000000000000000000000000000005525 166.0
TLS3_k127_8146305_4 Glycosyltransferase like family 2 K20444 - - 0.0000009825 61.0
TLS3_k127_8146637_0 PFAM ABC transporter related K02056 - 3.6.3.17 1.599e-194 619.0
TLS3_k127_8146637_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 587.0
TLS3_k127_8146637_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 422.0
TLS3_k127_8146637_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 414.0
TLS3_k127_8146637_4 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000001995 227.0
TLS3_k127_8146637_5 Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway K15525 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016137,GO:0016138,GO:0016787,GO:0016810,GO:0016811,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 3.5.1.103 0.0000000000000000000000000000000000000000000000000005179 198.0
TLS3_k127_8146637_6 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000466 154.0
TLS3_k127_8146637_7 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000001349 148.0
TLS3_k127_8146637_8 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000009793 97.0
TLS3_k127_8147880_0 AAA-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 470.0
TLS3_k127_8147880_1 Conjugative transposon protein TcpC - - - 0.00000000000001682 86.0
TLS3_k127_8147880_2 - - - - 0.0000000000003805 79.0
TLS3_k127_8147880_3 LysM domain - - - 0.000004329 51.0
TLS3_k127_8161671_0 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 8.146e-197 638.0
TLS3_k127_8161671_1 Signal transducing histidine kinase, homodimeric K02487,K03407,K06596 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 656.0
TLS3_k127_8161671_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 401.0
TLS3_k127_8161671_3 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 301.0
TLS3_k127_8161671_4 Methyl-accepting chemotaxis protein (MCP) signaling domain K02660,K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000334 268.0
TLS3_k127_8161671_5 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000005426 173.0
TLS3_k127_8161671_6 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000008439 138.0
TLS3_k127_8161671_7 response regulator receiver K03413 - - 0.0000000000000000000000000000000253 134.0
TLS3_k127_8161671_8 Chemotaxis phosphatase CheX K03409 - - 0.0000000000002374 81.0
TLS3_k127_8161671_9 RESPONSE REGULATOR receiver - - - 0.0000000006178 69.0
TLS3_k127_8164571_0 PFAM Peptidase M1, membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 2.681e-218 701.0
TLS3_k127_8164571_1 Beta propeller domain - - - 0.00000000005326 73.0
TLS3_k127_8182136_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 500.0
TLS3_k127_8182136_1 TIGRFAM Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 371.0
TLS3_k127_8182136_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004887 288.0
TLS3_k127_8182136_3 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000001862 211.0
TLS3_k127_8182136_4 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000001049 157.0
TLS3_k127_8204655_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 1.07e-240 756.0
TLS3_k127_8204655_1 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000001555 248.0
TLS3_k127_8205404_0 PFAM Helix-turn-helix - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000002915 132.0
TLS3_k127_8205404_1 L-asparaginase II - - - 0.000000000005754 71.0
TLS3_k127_8205404_2 Rho termination factor, N-terminal domain - - - 0.0006272 49.0
TLS3_k127_8212783_0 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944 1.6.5.3 3.577e-205 667.0
TLS3_k127_8212783_1 NADH-quinone oxidoreductase chain L K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 507.0
TLS3_k127_8212783_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 357.0
TLS3_k127_8212783_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 347.0
TLS3_k127_8212783_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 338.0
TLS3_k127_8212783_5 Belongs to the FPP GGPP synthase family K00805 - 2.5.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000005963 255.0
TLS3_k127_8212783_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K12143 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000006413 245.0
TLS3_k127_8212783_7 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000002969 142.0
TLS3_k127_8212783_8 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000001917 138.0
TLS3_k127_8212783_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.0000000000000000000000000001302 119.0
TLS3_k127_821575_0 trisaccharide binding - - - 5.831e-264 824.0
TLS3_k127_821575_1 ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 1.032e-245 772.0
TLS3_k127_821575_10 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation K13570 GO:0003674,GO:0005488,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0031386,GO:0032446,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044877,GO:0051603,GO:0070490,GO:0070628,GO:0070647,GO:0071704,GO:1901564,GO:1901565,GO:1901575 - 0.000000004609 59.0
TLS3_k127_821575_11 thiamine diphosphate biosynthetic process K03154 - - 0.000004166 59.0
TLS3_k127_821575_2 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 2.089e-196 623.0
TLS3_k127_821575_3 PP-loop family K21947 - 2.8.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 345.0
TLS3_k127_821575_4 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001164 277.0
TLS3_k127_821575_5 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000000000000000000000003641 271.0
TLS3_k127_821575_6 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019773,GO:0019941,GO:0030163,GO:0030312,GO:0032991,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000001281 239.0
TLS3_k127_821575_7 Domain of unknown function (DUF1802) - - - 0.000000000000000000000000000000000000000000000000000002455 199.0
TLS3_k127_821575_8 PFAM chitin-binding domain 3 protein K22033 - 1.14.99.56 0.000000000000000000000000000000000000000000000001915 193.0
TLS3_k127_821575_9 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000000000001235 121.0
TLS3_k127_8217063_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 565.0
TLS3_k127_8217063_1 glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000000000000000000000000000000000000000000000005346 184.0
TLS3_k127_8217063_2 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000001121 138.0
TLS3_k127_8217063_3 Ferric uptake regulator, Fur family K03711,K22297 - - 0.00000000000000000000000004569 119.0
TLS3_k127_8220872_0 PFAM RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 299.0
TLS3_k127_8220872_1 ferredoxin - - - 0.0000000000000000000000000000000000000000000009851 167.0
TLS3_k127_8220872_2 WHG domain - - - 0.000000000000000000000000000001672 133.0
TLS3_k127_8220872_3 acetyltransferase K22476 - 2.3.1.1 0.00000000000002182 76.0
TLS3_k127_8220872_4 PFAM regulatory protein, MarR - - - 0.00000001193 68.0
TLS3_k127_8220872_5 Fic/DOC family - - - 0.0001212 54.0
TLS3_k127_822342_0 Animal haem peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 580.0
TLS3_k127_822342_1 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007737 413.0
TLS3_k127_822342_2 PFAM Silent information regulator protein Sir2 K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 299.0
TLS3_k127_822342_3 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000000000003508 203.0
TLS3_k127_8240618_0 Dehydrogenase E1 component K11381 - 1.2.4.4 1.376e-317 996.0
TLS3_k127_8240618_1 helix_turn _helix lactose operon repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 306.0
TLS3_k127_8240618_2 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000001861 232.0
TLS3_k127_8240618_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000212 202.0
TLS3_k127_8240618_4 - - - - 0.000000000000000000000000000008832 123.0
TLS3_k127_8244838_0 heme binding K21471,K21472 - - 0.000000000000000000000000000000000003044 151.0
TLS3_k127_8244838_1 Permeases of the drug metabolite transporter (DMT) superfamily K03298 - - 0.000000000000000004874 92.0
TLS3_k127_8244838_2 Acetyltransferase (GNAT) domain - - - 0.00000000000003914 81.0
TLS3_k127_8244838_3 Belongs to the Nudix hydrolase family - - - 0.00000000001731 78.0
TLS3_k127_8244838_4 - - - - 0.0005063 50.0
TLS3_k127_8246259_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.231e-219 690.0
TLS3_k127_8246259_1 Helicase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008597 604.0
TLS3_k127_8246259_2 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 428.0
TLS3_k127_8246259_3 Evidence 4 Homologs of previously reported genes of K09927 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 409.0
TLS3_k127_8246259_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03087 GO:0000988,GO:0000990,GO:0001666,GO:0002791,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009410,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032879,GO:0032880,GO:0036293,GO:0040007,GO:0042221,GO:0043175,GO:0043254,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051173,GO:0051223,GO:0051252,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0070063,GO:0070201,GO:0070482,GO:0071944,GO:0080090,GO:0090087,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:1903530,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 325.0
TLS3_k127_8246259_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000735 235.0
TLS3_k127_8246259_6 Acetyltransferase (GNAT) domain K00657,K00663 - 2.3.1.57,2.3.1.82 0.000000000000000000000000000000000000000000000171 172.0
TLS3_k127_8246259_7 Nudix hydrolase K03574 - 3.6.1.55 0.00000000000000000000000000000000000003182 147.0
TLS3_k127_8246259_8 Protein of unknown function (DUF4235) - - - 0.00000000000000000001144 102.0
TLS3_k127_8246259_9 zinc finger - - - 0.0000000000006545 78.0
TLS3_k127_8252613_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003169 281.0
TLS3_k127_8252613_1 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000001918 257.0
TLS3_k127_8252613_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001714 256.0
TLS3_k127_8252613_3 ABC-2 type transporter K01992 - - 0.000000000000000000001432 109.0
TLS3_k127_8252613_4 NAD(P)H-binding - - - 0.0000415 51.0
TLS3_k127_8260733_0 metallopeptidase activity K01179 - 3.2.1.4 1.61e-261 841.0
TLS3_k127_8260733_1 Aminotransferase K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 479.0
TLS3_k127_8260733_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 393.0
TLS3_k127_8260733_3 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000009628 222.0
TLS3_k127_8260733_4 Domain of unknown function (DUF1929) - - - 0.0000000000000000000000005526 123.0
TLS3_k127_8260733_5 SnoaL-like domain - - - 0.0000000000006958 75.0
TLS3_k127_8260733_6 Delta-aminolevulinic acid dehydratase K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000001429 68.0
TLS3_k127_8260733_7 WD40 repeat-containing protein - - - 0.000000001183 64.0
TLS3_k127_8262861_0 TIGRFAM DNA polymerase LigD, polymerase domain protein K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003798 279.0
TLS3_k127_8262861_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009347 249.0
TLS3_k127_8262861_2 FxsA cytoplasmic membrane protein K07113 - - 0.000000000000000000000000000002133 130.0
TLS3_k127_8272295_0 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 386.0
TLS3_k127_8272295_1 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001151 261.0
TLS3_k127_8272295_2 LUD domain K00782 - - 0.000000000000000000000000000000000000001343 148.0
TLS3_k127_8272295_3 PFAM regulatory protein, MarR - - - 0.00000000000000000000002418 104.0
TLS3_k127_8272295_4 Major facilitator Superfamily - - - 0.0000000002552 70.0
TLS3_k127_8272499_0 DEAD DEAH box helicase domain protein K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 2.016e-220 722.0
TLS3_k127_8272499_1 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 1.602e-219 692.0
TLS3_k127_8272499_10 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.0000000000000000000000001486 122.0
TLS3_k127_8272499_11 - - - - 0.00000000000000000002733 94.0
TLS3_k127_8272499_12 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000002214 60.0
TLS3_k127_8272499_2 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 414.0
TLS3_k127_8272499_3 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 359.0
TLS3_k127_8272499_4 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 332.0
TLS3_k127_8272499_5 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 312.0
TLS3_k127_8272499_6 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 309.0
TLS3_k127_8272499_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000001658 224.0
TLS3_k127_8272499_8 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000353 183.0
TLS3_k127_8272499_9 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000183 167.0
TLS3_k127_8278286_0 epimerase dehydratase K01710,K01784 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.46,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 323.0
TLS3_k127_8278286_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001858 245.0
TLS3_k127_8278286_2 belongs to the sigma-70 factor family, ECF subfamily K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000006963 233.0
TLS3_k127_8278286_3 anti-sigma factor - GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.000000313 55.0
TLS3_k127_8278286_4 Sigma-70 factor, region 1.2 - - - 0.000004929 52.0
TLS3_k127_8284983_0 - - - - 0.00000000000000000000000000000000000000000000000000000002341 211.0
TLS3_k127_8284983_1 domain, Protein - - - 0.00000000000000000000000000004174 126.0
TLS3_k127_8284983_2 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000008982 116.0
TLS3_k127_8284983_3 - - - - 0.00000000000001436 82.0
TLS3_k127_8284983_4 Histidine kinase - - - 0.00000000000002075 86.0
TLS3_k127_8297722_0 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 483.0
TLS3_k127_8297722_1 Permease family K06901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 447.0
TLS3_k127_8297722_10 - K10716 - - 0.0000000000000000000000000000000000000000000000000000000511 206.0
TLS3_k127_8297722_11 Male sterility protein - - - 0.00000000000000000000000000000000000000000001936 169.0
TLS3_k127_8297722_12 ANTAR domain protein - - - 0.0000000000000000000000000000000000000000009139 166.0
TLS3_k127_8297722_13 permease - - - 0.0000000000000000000000000000000000004919 156.0
TLS3_k127_8297722_14 ABC-type transport system involved in multi-copper enzyme maturation, permease K01992 - - 0.00000000000000000000000000000254 130.0
TLS3_k127_8297722_15 - - - - 0.00000000000000000000000000001981 124.0
TLS3_k127_8297722_16 - - - - 0.000000000000000000000000002994 120.0
TLS3_k127_8297722_17 Protein of unknown function (DUF3618) - - - 0.0000000000000000000000001242 118.0
TLS3_k127_8297722_18 Protein of unknown function (DUF3072) - - - 0.00000000000000000000003389 100.0
TLS3_k127_8297722_19 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000000000000000000002538 104.0
TLS3_k127_8297722_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 341.0
TLS3_k127_8297722_20 ATP synthesis coupled proton transport K02109 - - 0.00000000000000000001187 103.0
TLS3_k127_8297722_21 - - - - 0.000000000000000004882 90.0
TLS3_k127_8297722_22 Peptidase family M23 K21472 - - 0.00000000000000002437 95.0
TLS3_k127_8297722_23 S-layer homology domain - - - 0.0000000000000007398 91.0
TLS3_k127_8297722_24 - - - - 0.0000000006005 64.0
TLS3_k127_8297722_26 - - - - 0.00000003376 61.0
TLS3_k127_8297722_27 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0002199 50.0
TLS3_k127_8297722_28 - - - - 0.0002835 49.0
TLS3_k127_8297722_3 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 301.0
TLS3_k127_8297722_4 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 289.0
TLS3_k127_8297722_5 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008603 291.0
TLS3_k127_8297722_6 Pfam Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006571 257.0
TLS3_k127_8297722_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000005311 240.0
TLS3_k127_8297722_8 COG1226 Kef-type K transport systems - - - 0.00000000000000000000000000000000000000000000000000000000007236 216.0
TLS3_k127_8297722_9 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000008674 229.0
TLS3_k127_8312131_0 PhoH-like protein K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 408.0
TLS3_k127_8312131_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 316.0
TLS3_k127_8312131_2 PFAM CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000147 267.0
TLS3_k127_8312131_3 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000086 213.0
TLS3_k127_8312131_4 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000000000000008483 199.0
TLS3_k127_8312131_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000001266 128.0
TLS3_k127_8312131_6 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000228 123.0
TLS3_k127_8312131_7 Histidine triad (Hit) protein K02503 - - 0.0000000000000000002025 90.0
TLS3_k127_8329475_0 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 382.0
TLS3_k127_8329475_1 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000000000000000000000000007538 221.0
TLS3_k127_8329475_2 ANTAR domain protein - - - 0.0000000000000004192 91.0
TLS3_k127_8329475_3 Phage integrase family - - - 0.000000004402 59.0
TLS3_k127_832955_0 Adenosine deaminase K01488 GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 308.0
TLS3_k127_832955_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 299.0
TLS3_k127_832955_2 geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001003 257.0
TLS3_k127_832955_3 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000001178 245.0
TLS3_k127_832955_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000004066 226.0
TLS3_k127_832955_5 Histidine triad (Hit) protein K02503 - - 0.000000000000000000000000000000000004253 156.0
TLS3_k127_832955_6 KR domain - - - 0.000000000000000000000000000000000006814 149.0
TLS3_k127_833490_0 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 326.0
TLS3_k127_833490_1 Major facilitator Superfamily - - - 0.00000000000000000000000000007778 130.0
TLS3_k127_8354385_0 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007052 398.0
TLS3_k127_8354385_1 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000005563 239.0
TLS3_k127_8354385_2 ANTAR domain protein - - - 0.0000000000000000000000004927 112.0
TLS3_k127_8368590_0 Sulfotransferase family - - - 0.00000000000000000000000001198 124.0
TLS3_k127_8368590_1 Sulfotransferase domain - - - 0.000000000000000000000002216 116.0
TLS3_k127_8368590_2 ADP-L-glycero-beta-D-manno-heptose biosynthetic process - - - 0.0000000000000000001388 97.0
TLS3_k127_8368590_3 Sulfotransferase domain - - - 0.00000000000000004808 96.0
TLS3_k127_8368590_4 O-Antigen ligase - - - 0.000000000001589 81.0
TLS3_k127_8368590_5 Chain length determinant protein - - - 0.0000607 53.0
TLS3_k127_8368590_6 Sulfotransferase family - - - 0.00007873 55.0
TLS3_k127_8371720_0 hydrolase, family 3 K05349 - 3.2.1.21 0.0 1134.0
TLS3_k127_8371720_1 Galactose mutarotase-like K01811 - 3.2.1.177 0.0 1057.0
TLS3_k127_8371720_10 Cobalt transport protein K16783 - - 0.000000000000000000000000000000000001671 149.0
TLS3_k127_8371720_11 Phosphoglycerate mutase family - - - 0.00000000000000000000000002564 115.0
TLS3_k127_8371720_12 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000002369 93.0
TLS3_k127_8371720_13 Cro/C1-type HTH DNA-binding domain K07727 - - 0.0000000000131 76.0
TLS3_k127_8371720_2 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 441.0
TLS3_k127_8371720_3 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 365.0
TLS3_k127_8371720_4 PFAM Xylose isomerase-like TIM barrel K18910 - 5.1.3.30,5.1.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 344.0
TLS3_k127_8371720_5 Binding-protein-dependent transport systems inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 293.0
TLS3_k127_8371720_6 ABC transporter K02006,K16784 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001381 282.0
TLS3_k127_8371720_7 PFAM binding-protein-dependent transport systems inner membrane component K02025,K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000001946 248.0
TLS3_k127_8371720_8 biotin transmembrane transporter activity K03523 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000001298 203.0
TLS3_k127_8371720_9 transcriptional regulator - - - 0.0000000000000000000000000000000000000000004822 172.0
TLS3_k127_8373042_0 KR domain - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0018193,GO:0018205,GO:0019538,GO:0030312,GO:0032446,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070490,GO:0070647,GO:0071704,GO:0071944,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 377.0
TLS3_k127_8373042_2 Helix-turn-helix domain - - - 0.000000000000002292 79.0
TLS3_k127_8375592_0 IucA IucC family protein - - - 2.217e-246 778.0
TLS3_k127_8375592_1 L-lysine 6-monooxygenase (NADPH-requiring) K03897 - 1.14.13.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 408.0
TLS3_k127_8375592_2 IucA IucC family protein - - - 0.000000000000000000000000000000000000000000000000000001335 212.0
TLS3_k127_8375592_3 Acyltransferase family - - - 0.000000000000000000000000009228 114.0
TLS3_k127_8375592_4 Acyltransferase family - - - 0.00001084 56.0
TLS3_k127_8376708_0 Aminotransferase class-V - - - 3.437e-214 679.0
TLS3_k127_8376708_1 FAD binding domain K00480,K22270 GO:0000166,GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0018669,GO:0019439,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044248,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.14.13.1,1.14.13.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 586.0
TLS3_k127_8376708_2 PFAM glycoside hydrolase, family 10 K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 504.0
TLS3_k127_8376708_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000007743 239.0
TLS3_k127_8376708_4 Histidine kinase - - - 0.000000000000000000000000001147 122.0
TLS3_k127_838232_0 Xylose isomerase-like TIM barrel K00457 - 1.13.11.27 5.58e-208 666.0
TLS3_k127_838232_1 - - - - 0.000000000000000000000003844 110.0
TLS3_k127_8389065_0 Carotenoid biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000001048 221.0
TLS3_k127_8389065_1 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000108 200.0
TLS3_k127_8398187_0 HNH nucleases - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000003822 57.0
TLS3_k127_8398187_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.0000112 59.0
TLS3_k127_8407057_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 421.0
TLS3_k127_8407057_1 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 310.0
TLS3_k127_8407057_2 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000001545 231.0
TLS3_k127_8407057_3 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.000000000000000000000000000000000000000002672 173.0
TLS3_k127_8407057_4 - - - - 0.00000000000000000000000005676 121.0
TLS3_k127_8407057_5 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.000000000004222 74.0
TLS3_k127_8415719_0 Domain of unknown function (DUF4032) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 422.0
TLS3_k127_8415719_1 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 396.0
TLS3_k127_8415719_10 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000001701 217.0
TLS3_k127_8415719_11 ABC-type Na efflux pump, permease K01992 - - 0.0000000000000000000000000000000000000000000000000002112 205.0
TLS3_k127_8415719_12 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000007932 132.0
TLS3_k127_8415719_13 Stf0 sulphotransferase K21014 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006725,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009311,GO:0009987,GO:0016020,GO:0016740,GO:0016782,GO:0017076,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044262,GO:0044272,GO:0044281,GO:0044464,GO:0046483,GO:0046505,GO:0046506,GO:0046983,GO:0050427,GO:0050656,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901681 2.8.2.37 0.0002298 53.0
TLS3_k127_8415719_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 359.0
TLS3_k127_8415719_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 311.0
TLS3_k127_8415719_4 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 312.0
TLS3_k127_8415719_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 295.0
TLS3_k127_8415719_6 phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004614 292.0
TLS3_k127_8415719_7 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007957 272.0
TLS3_k127_8415719_8 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004405 264.0
TLS3_k127_8415719_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000144 230.0
TLS3_k127_8418553_0 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 475.0
TLS3_k127_8418553_1 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006146 256.0
TLS3_k127_8418553_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001783 249.0
TLS3_k127_8418553_3 regulation of RNA biosynthetic process - - - 0.0000000000000000000000000001641 119.0
TLS3_k127_8418553_5 sequence-specific DNA binding K07467 - - 0.000000000001224 81.0
TLS3_k127_8418553_6 ATP-dependent Clp protease, proteolytic subunit - - - 0.00000000003357 74.0
TLS3_k127_8425356_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 1.31e-316 1043.0
TLS3_k127_8425356_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000001128 244.0
TLS3_k127_8425356_2 FIST N domain - - - 0.00000000000000000000000000000000000000000000000000001901 199.0
TLS3_k127_8434342_0 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 4.007e-259 817.0
TLS3_k127_8434342_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18313 - 2.8.3.16,2.8.3.20 1.946e-198 623.0
TLS3_k127_8434342_2 FCD - - - 0.00000000000000000000000000000000000000000000000000000016 201.0
TLS3_k127_8434342_3 Belongs to the sigma-70 factor family - - - 0.0000000000000000000000000000000000005655 161.0
TLS3_k127_8434342_4 SMI1 / KNR4 family - - - 0.00000000000000000000000000007308 134.0
TLS3_k127_8437432_0 Na H antiporter K05565,K14086 - - 4.093e-205 664.0
TLS3_k127_8437432_1 Proton-conducting membrane transporter K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 577.0
TLS3_k127_8437432_2 endonuclease III K03575 - - 0.000000000000000000000000000000000000000000000000000000000000006233 227.0
TLS3_k127_8437432_3 Subunit A of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K05565,K14086 - - 0.000000000000000000000000000000000000004833 154.0
TLS3_k127_8437432_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000003419 150.0
TLS3_k127_8437432_5 Multisubunit Na H antiporter, MnhC subunit K05567 - - 0.000000000000000000000000000000007234 134.0
TLS3_k127_8437432_6 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000001559 142.0
TLS3_k127_8437432_7 monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.00000000000000000009202 97.0
TLS3_k127_8437432_8 multisubunit Na H antiporter MnhE subunit K05569 - - 0.0000000000000000001015 105.0
TLS3_k127_8437432_9 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.000000005694 61.0
TLS3_k127_8457714_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 550.0
TLS3_k127_8457714_1 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 341.0
TLS3_k127_8461846_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.362e-212 671.0
TLS3_k127_8461846_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.3.14 2.837e-208 673.0
TLS3_k127_8461846_10 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000007719 102.0
TLS3_k127_8461846_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000005891 92.0
TLS3_k127_8461846_12 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex - - - 0.00008575 52.0
TLS3_k127_8461846_2 ATP dependent DNA ligase C terminal region K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 516.0
TLS3_k127_8461846_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002552 268.0
TLS3_k127_8461846_4 Uracil DNA glycosylase superfamily K03649 - 3.2.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000002604 267.0
TLS3_k127_8461846_5 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000008698 201.0
TLS3_k127_8461846_6 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000004342 171.0
TLS3_k127_8461846_7 Belongs to the SUA5 family K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.000000000000000000000000000000000000000004362 163.0
TLS3_k127_8461846_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109,K02113 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000012 116.0
TLS3_k127_8461846_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000009594 99.0
TLS3_k127_8467596_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 569.0
TLS3_k127_8467596_1 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 0.0000000000000000000000000000000000000000000008118 168.0
TLS3_k127_8467596_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00124 - - 0.0000000000000000000000000000004783 129.0
TLS3_k127_8491422_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 2.283e-265 829.0
TLS3_k127_8491422_1 Uroporphyrinogen III synthase HEM4 K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000002562 261.0
TLS3_k127_8491422_2 TIGRFAM Haloacid Dehalogenase Superfamily Class (subfamily) IIA - GO:0000121,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030145,GO:0042578,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0046434,GO:0046475,GO:0046486,GO:0046503,GO:0046872,GO:0046914,GO:0046983,GO:0050897,GO:0071704,GO:1901575 - 0.00000000000000000000000000000000000000000000000004889 187.0
TLS3_k127_8491422_3 Binds directly to 16S ribosomal RNA K02968 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000002416 85.0
TLS3_k127_8491422_4 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000002143 63.0
TLS3_k127_8493067_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 GO:0008150,GO:0040007 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009107 400.0
TLS3_k127_8493067_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000005096 170.0
TLS3_k127_8493067_2 UTRA K03710 - - 0.0000000000000000000000000000000000000000007697 167.0
TLS3_k127_8493067_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000000002946 160.0
TLS3_k127_8493067_4 response regulator, receiver - - - 0.000000000000000000000000000000000000002288 158.0
TLS3_k127_8493067_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000006914 133.0
TLS3_k127_8493067_6 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000005015 107.0
TLS3_k127_8493067_7 - - - - 0.0000000000000000000003027 103.0
TLS3_k127_8493067_8 Protein of unknown function (DUF1232) - - - 0.000000000000001629 81.0
TLS3_k127_8493067_9 CAAX protease self-immunity K07052 - - 0.00000000000335 76.0
TLS3_k127_8494314_0 Aldehyde dehydrogenase family K00141 - 1.2.1.28 4.37e-236 740.0
TLS3_k127_8494314_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 520.0
TLS3_k127_8494314_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 306.0
TLS3_k127_8494314_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000006174 243.0
TLS3_k127_8494314_4 60Kd inner membrane protein K03217 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000001021 162.0
TLS3_k127_8494314_5 Multicopper oxidase K00368 - 1.7.2.1 0.000000000000000000000000000002378 138.0
TLS3_k127_8500199_0 GDP-mannose 4,6 dehydratase K06118 - 3.13.1.1 2.132e-208 654.0
TLS3_k127_8500199_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 599.0
TLS3_k127_8500199_2 Adenosine/AMP deaminase K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 510.0
TLS3_k127_8500199_3 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 440.0
TLS3_k127_8500199_4 Male sterility protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 332.0
TLS3_k127_8500199_5 GtrA-like protein - - - 0.0000000000001777 79.0
TLS3_k127_8500199_6 Domain of unknown function (DUF3459) K01187 - 3.2.1.20 0.00001225 51.0
TLS3_k127_8505723_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 2.104e-227 732.0
TLS3_k127_8505723_1 PFAM Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 421.0
TLS3_k127_8505723_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 333.0
TLS3_k127_8505723_3 alcohol dehydrogenase - - - 0.000000000002126 70.0
TLS3_k127_8505723_4 - - - - 0.000001533 60.0
TLS3_k127_8528299_0 synthase K01654 - 2.5.1.56 2.866e-275 874.0
TLS3_k127_8528299_1 ABC-type multidrug transport system ATPase and permease K06147,K06148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 376.0
TLS3_k127_8528299_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003142 273.0
TLS3_k127_8528299_4 -O-antigen K02847 - - 0.00000000000000000000000000000000000000000000000000002487 212.0
TLS3_k127_8528299_5 Sulfotransferase family - - - 0.000000000000000000000000000000000006288 156.0
TLS3_k127_8528299_6 slime layer polysaccharide biosynthetic process - - - 0.000000000000000000000000000009202 124.0
TLS3_k127_8528299_7 - - - - 0.00000000000000000000147 109.0
TLS3_k127_8535207_0 asparagine K01953 - 6.3.5.4 7.012e-275 857.0
TLS3_k127_8535207_1 D-ala D-ala ligase C-terminus K03802 - 6.3.2.29,6.3.2.30 7.813e-222 702.0
TLS3_k127_8535207_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000001124 166.0
TLS3_k127_8535207_3 PFAM Pyridoxamine 5'-phosphate - - - 0.00000000000000000000000000000000000000000005881 166.0
TLS3_k127_8537487_0 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K05565,K14086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 394.0
TLS3_k127_8548806_0 GTP-binding protein TypA K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 574.0
TLS3_k127_8548806_1 Serine aminopeptidase, S33 K06889 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071944,GO:0075136 - 0.00000000000000000000000000000000000000000000000000000000000000001869 234.0
TLS3_k127_8571517_0 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 316.0
TLS3_k127_8571517_1 MerR HTH family regulatory protein K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000003764 115.0
TLS3_k127_8571517_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - 0.0000000000000000001774 90.0
TLS3_k127_8576763_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 6.1.1.15 1.575e-271 848.0
TLS3_k127_8576763_1 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000004297 104.0
TLS3_k127_85896_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1128.0
TLS3_k127_887150_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000003434 166.0
TLS3_k127_887150_1 SLBB domain K02237 - - 0.000000004699 59.0
TLS3_k127_889341_0 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001758 256.0
TLS3_k127_889341_1 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009008 251.0
TLS3_k127_889341_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.00000000002627 67.0
TLS3_k127_893572_0 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009937 514.0
TLS3_k127_893572_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000004427 234.0
TLS3_k127_893572_2 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000006371 168.0
TLS3_k127_893572_3 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000007753 138.0
TLS3_k127_904936_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 501.0
TLS3_k127_904936_1 Cell wall formation K00075 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000001151 224.0
TLS3_k127_904936_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000001615 201.0
TLS3_k127_904936_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000001031 159.0
TLS3_k127_904936_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944 - 0.0000000000000000000000000000000008396 140.0
TLS3_k127_904936_5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000001681 115.0
TLS3_k127_904936_6 Cell division protein FtsQ K03589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.000000151 62.0
TLS3_k127_904936_7 Integral membrane protein K02221 - - 0.0000007937 54.0
TLS3_k127_904936_8 DivIVA domain protein K04074 - - 0.000003709 58.0
TLS3_k127_9061_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 541.0
TLS3_k127_9061_1 Riboflavin synthase K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000007055 224.0
TLS3_k127_9061_2 Type IV leader peptidase family K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000001737 220.0
TLS3_k127_9061_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000001441 179.0
TLS3_k127_9061_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000007667 87.0
TLS3_k127_914868_0 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0016054,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0046395,GO:0046487,GO:0046872,GO:0046912,GO:0071704,GO:0072329,GO:1901575 2.3.3.9 1.891e-310 969.0
TLS3_k127_914868_1 ABC transporter K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 489.0
TLS3_k127_914868_2 Substrate binding domain of ABC-type glycine betaine transport system K05845 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003954 270.0
TLS3_k127_914868_3 Binding-protein-dependent transport system inner membrane component K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000002943 234.0
TLS3_k127_914868_4 phosphatidylcholine synthase activity K01004,K17103 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24,2.7.8.8 0.0000000000000000000000000000000000000000000000000000000002903 215.0
TLS3_k127_914868_5 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000003001 200.0
TLS3_k127_914868_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000001744 193.0
TLS3_k127_914868_7 Haem-degrading - - - 0.000000000000000000000000000000000000000000000001847 177.0
TLS3_k127_914868_8 ABC transporter permease K05846 - - 0.000000000000000000000000000000000000000000000106 193.0
TLS3_k127_914868_9 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000004028 127.0
TLS3_k127_915724_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 8.605e-197 643.0
TLS3_k127_915724_1 FIST_C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002532 278.0
TLS3_k127_915724_2 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000157 145.0
TLS3_k127_929410_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 405.0
TLS3_k127_929410_1 Acyl-CoA oxidase K00232 - 1.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 351.0
TLS3_k127_929410_2 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002405 243.0
TLS3_k127_929410_3 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000008938 216.0
TLS3_k127_929410_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000003467 172.0
TLS3_k127_929410_5 transcriptional regulator - - - 0.00000000000000000000000000000007581 143.0
TLS3_k127_929410_7 Sulfotransferase domain - - - 0.00000000000000008393 90.0
TLS3_k127_943874_0 belongs to the aldehyde dehydrogenase family K00130,K00151 - 1.2.1.60,1.2.1.8 3.551e-226 721.0
TLS3_k127_943874_1 belongs to the aldehyde dehydrogenase family K09472,K12254 - 1.2.1.54,1.2.1.99 2.425e-202 646.0
TLS3_k127_943874_10 Clp amino terminal domain, pathogenicity island component - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000002463 222.0
TLS3_k127_943874_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000001608 157.0
TLS3_k127_943874_12 Protein of unknown function (DUF3156) - - - 0.000000000000000000000000004557 118.0
TLS3_k127_943874_13 Peptidase C26 - - - 0.0000000000000000006893 89.0
TLS3_k127_943874_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 548.0
TLS3_k127_943874_3 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 520.0
TLS3_k127_943874_4 Fumarylacetoacetate (FAA) hydrolase family K05921 - 4.1.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 467.0
TLS3_k127_943874_5 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 445.0
TLS3_k127_943874_6 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 411.0
TLS3_k127_943874_7 Acetoacetate decarboxylase (ADC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 360.0
TLS3_k127_943874_8 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 361.0
TLS3_k127_943874_9 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 336.0
TLS3_k127_945425_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 422.0
TLS3_k127_945425_1 Histidine kinase K11527 - 2.7.13.3 0.00000000000000000000001504 110.0
TLS3_k127_945425_2 glyoxalase - - - 0.0000000000000000008476 87.0
TLS3_k127_978186_0 helicase superfamily c-terminal domain K03654 - 3.6.4.12 2.231e-220 704.0
TLS3_k127_978186_1 Animal haem peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 643.0
TLS3_k127_978186_2 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000108 213.0
TLS3_k127_978186_3 Forkhead associated domain - - - 0.00000000000000000000000000000000001774 156.0
TLS3_k127_978186_4 Lactonase, 7-bladed beta-propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000002593 143.0
TLS3_k127_978186_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000001289 136.0
TLS3_k127_978186_6 Belongs to the glycosyl hydrolase family 6 K19668 - 3.2.1.91 0.0000000000000000000000000002798 134.0
TLS3_k127_978186_7 DNA polymerase III, beta - - - 0.0000000000000002481 85.0
TLS3_k127_984816_0 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006931 408.0
TLS3_k127_984816_1 helicase superfamily c-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 401.0
TLS3_k127_984816_10 ATPases associated with a variety of cellular activities K01990,K01992 - - 0.00000001079 58.0
TLS3_k127_984816_2 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 338.0
TLS3_k127_984816_3 Abc-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001084 283.0
TLS3_k127_984816_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002229 294.0
TLS3_k127_984816_5 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001663 262.0
TLS3_k127_984816_6 - - - - 0.00000000000000000000000000000000000000000000000000000008866 205.0
TLS3_k127_984816_7 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000000000004248 177.0
TLS3_k127_984816_8 Sigma-70, region 4 - - - 0.0000000000000006728 91.0
TLS3_k127_984816_9 Bifunctional nuclease K08999 - - 0.00000000000002704 85.0