logo

Overview

ID MAG04052
Name TLS3_bin.30
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Anaerolineae
Order Anaerolineales
Family Villigracilaceae
Genus Villigracilis
Species
Assembly information
Completeness (%) 95.41
Contamination (%) 3.44
GC content (%) 55.0
N50 (bp) 14,042
Genome size (bp) 3,184,841

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2893

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1003810_0 ABC transporter K10548 - 3.6.3.17 1.721e-249 781.0
TLS3_k127_1003810_1 maltose binding K02027 - - 7.09e-246 767.0
TLS3_k127_1003810_10 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 375.0
TLS3_k127_1003810_11 Periplasmic binding protein-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 323.0
TLS3_k127_1003810_12 Haem-degrading - - - 0.00000000000000000002984 92.0
TLS3_k127_1003810_13 PFAM ADP-ribosylation Crystallin J1 - - - 0.0005693 43.0
TLS3_k127_1003810_2 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 1.622e-206 651.0
TLS3_k127_1003810_3 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 570.0
TLS3_k127_1003810_4 ABC-type xylose transport system, periplasmic component K02058,K10546 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 502.0
TLS3_k127_1003810_5 PFAM Branched-chain amino acid transport system permease component K10547 GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0019321,GO:0031224,GO:0042732,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0071704,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 499.0
TLS3_k127_1003810_6 PFAM ROK family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 470.0
TLS3_k127_1003810_7 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 463.0
TLS3_k127_1003810_8 N-acetylglucosaminylinositol deacetylase activity K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 406.0
TLS3_k127_1003810_9 PFAM glycoside hydrolase, family 3 domain protein K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 395.0
TLS3_k127_1017648_0 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008617 496.0
TLS3_k127_1017648_1 hydrolase activity, hydrolyzing O-glycosyl compounds K00690 - 2.4.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 351.0
TLS3_k127_1017648_2 SpoU rRNA Methylase family - - - 0.0000000000000000000000000000000000000000000000000821 184.0
TLS3_k127_1017648_3 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000002212 175.0
TLS3_k127_1017648_4 Multisubunit Na H antiporter MnhC subunit K00340,K05567 - 1.6.5.3 0.00000000000000000000000007357 109.0
TLS3_k127_1017648_5 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000001229 112.0
TLS3_k127_1017648_6 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein - - - 0.0000000000000000006906 89.0
TLS3_k127_1017648_7 GDSL-like Lipase/Acylhydrolase - GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0016298,GO:0016787,GO:0016788,GO:0052689 - 0.000000000001579 78.0
TLS3_k127_1018543_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.25e-318 985.0
TLS3_k127_1018543_1 PFAM type II secretion system protein E K02283 - - 9.081e-234 731.0
TLS3_k127_1018543_10 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000002875 216.0
TLS3_k127_1018543_11 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000001015 206.0
TLS3_k127_1018543_12 phosphinothricin N-acetyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000001674 205.0
TLS3_k127_1018543_13 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000000009997 194.0
TLS3_k127_1018543_14 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000003438 193.0
TLS3_k127_1018543_15 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000001422 186.0
TLS3_k127_1018543_16 competence protein - - - 0.00000000000000000000000000000000000000000000000003645 187.0
TLS3_k127_1018543_17 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000003352 168.0
TLS3_k127_1018543_2 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 544.0
TLS3_k127_1018543_3 PFAM response regulator receiver K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 477.0
TLS3_k127_1018543_4 ATP hydrolysis coupled proton transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 424.0
TLS3_k127_1018543_5 PFAM type II secretion system protein K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 374.0
TLS3_k127_1018543_6 histidine kinase, dimerisation and phosphoacceptor region K07777 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 362.0
TLS3_k127_1018543_7 PFAM type II secretion system protein K12510 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 350.0
TLS3_k127_1018543_9 Flp pilus assembly protein CpaB K02279 - - 0.0000000000000000000000000000000000000000000000000000000000002867 224.0
TLS3_k127_102577_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.178e-278 867.0
TLS3_k127_102577_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 511.0
TLS3_k127_102577_10 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004919 266.0
TLS3_k127_102577_11 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000006165 243.0
TLS3_k127_102577_12 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000004582 244.0
TLS3_k127_102577_13 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000001289 213.0
TLS3_k127_102577_14 maltose-transporting ATPase activity K15772 - - 0.000000000000000000000000000000000000000000000000006476 192.0
TLS3_k127_102577_15 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000005401 185.0
TLS3_k127_102577_16 Nitroreductase family - - - 0.0000000000000000000000000000000000000000008037 164.0
TLS3_k127_102577_17 PFAM binding-protein-dependent transport systems inner membrane component K15771 - - 0.0000000000000000000000000003828 132.0
TLS3_k127_102577_19 - - - - 0.0000000000000000000002546 113.0
TLS3_k127_102577_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 480.0
TLS3_k127_102577_21 response regulator receiver - - - 0.00000000000009157 77.0
TLS3_k127_102577_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 468.0
TLS3_k127_102577_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 465.0
TLS3_k127_102577_5 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 441.0
TLS3_k127_102577_6 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 416.0
TLS3_k127_102577_7 Metallopeptidase family M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 370.0
TLS3_k127_102577_8 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 356.0
TLS3_k127_102577_9 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 352.0
TLS3_k127_104839_0 May be involved in recombinational repair of damaged DNA K03631 - - 8.274e-212 672.0
TLS3_k127_104839_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 310.0
TLS3_k127_104839_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 304.0
TLS3_k127_104839_3 Phosphoribosyl transferase domain K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000003818 198.0
TLS3_k127_104839_4 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.0000000000000000000000000000000000000000000000000005595 190.0
TLS3_k127_104839_5 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000000007691 133.0
TLS3_k127_104839_7 - - - - 0.0000000000005183 75.0
TLS3_k127_104839_8 Protein of unknown function (DUF998) - - - 0.000000007146 64.0
TLS3_k127_1055081_0 Zinc-binding dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 473.0
TLS3_k127_1055081_1 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.000000000001193 73.0
TLS3_k127_1055081_2 Histidine kinase-like ATPase domain K04749,K04757 - 2.7.11.1 0.00000002101 59.0
TLS3_k127_1062158_0 CHASE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 464.0
TLS3_k127_1062158_1 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 419.0
TLS3_k127_1062158_10 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000004528 158.0
TLS3_k127_1062158_2 PFAM ribonucleotide reductase K00526 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008828 385.0
TLS3_k127_1062158_3 Magnesium transport protein CorA K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 320.0
TLS3_k127_1062158_4 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 308.0
TLS3_k127_1062158_5 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 293.0
TLS3_k127_1062158_6 PFAM SMP-30 Gluconolaconase LRE domain protein K14274 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001796 290.0
TLS3_k127_1062158_7 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000002844 235.0
TLS3_k127_1062158_8 Response regulator receiver K07696 - - 0.000000000000000000000000000000000000000000000000005698 191.0
TLS3_k127_1062158_9 GGDEF domain K01768,K20977 - 4.6.1.1 0.0000000000000000000000000000000000000000005946 171.0
TLS3_k127_1116657_0 histidine kinase A domain protein - - - 1.611e-253 819.0
TLS3_k127_1116657_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 4.365e-242 758.0
TLS3_k127_1116657_10 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000003511 283.0
TLS3_k127_1116657_11 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000052 267.0
TLS3_k127_1116657_12 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002271 240.0
TLS3_k127_1116657_13 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000002913 254.0
TLS3_k127_1116657_14 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000008952 252.0
TLS3_k127_1116657_15 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000000000000000000001359 225.0
TLS3_k127_1116657_16 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000003358 224.0
TLS3_k127_1116657_17 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000001277 212.0
TLS3_k127_1116657_18 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000006482 197.0
TLS3_k127_1116657_19 - - - - 0.00000000000000000000000000000000000000000007729 163.0
TLS3_k127_1116657_2 SMART ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000582 447.0
TLS3_k127_1116657_20 cheY-homologous receiver domain K11443 - - 0.0000000000000000000000000000000000000000001591 162.0
TLS3_k127_1116657_21 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.0000000000000000000000000000000000000006881 168.0
TLS3_k127_1116657_22 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.00000000000000000000000000008013 121.0
TLS3_k127_1116657_23 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000456 93.0
TLS3_k127_1116657_24 His Kinase A (phosphoacceptor) domain - - - 0.00000000000003828 86.0
TLS3_k127_1116657_3 phosphorelay sensor kinase activity K01768,K02482,K02584,K07673,K10819 - 2.7.13.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008306 438.0
TLS3_k127_1116657_4 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 383.0
TLS3_k127_1116657_5 spore germination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008181 317.0
TLS3_k127_1116657_6 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 333.0
TLS3_k127_1116657_7 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 304.0
TLS3_k127_1116657_8 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003884 293.0
TLS3_k127_1116657_9 PFAM Cobyrinic acid a,c-diamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000378 272.0
TLS3_k127_1133036_0 thiosulfate sulfurtransferase activity K01011 - 2.8.1.1,2.8.1.2 1.108e-199 638.0
TLS3_k127_1133036_1 thiosulfate sulfurtransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007237 490.0
TLS3_k127_1133036_2 PFAM Vitamin K epoxide reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000137 283.0
TLS3_k127_1133036_3 Ferrous iron transport protein B K04759 - - 0.000000000000000000000000000000000000000000000000000000001658 206.0
TLS3_k127_1133036_4 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000006096 211.0
TLS3_k127_1133036_5 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000002675 190.0
TLS3_k127_1133036_6 Iron dependent repressor, metal binding and dimerisation domain K03709 - - 0.000000000000000000000000000000000000005192 153.0
TLS3_k127_1133036_7 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000428 80.0
TLS3_k127_114334_0 aminopeptidase activity K01179,K01269 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 437.0
TLS3_k127_114334_1 PFAM luciferase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 384.0
TLS3_k127_114334_2 MazG nucleotide pyrophosphohydrolase domain - - - 0.000000001503 59.0
TLS3_k127_1151564_0 PFAM AAA ATPase central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 460.0
TLS3_k127_1151564_1 Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 368.0
TLS3_k127_1151564_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000216 219.0
TLS3_k127_1151564_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.000000000000000000000000005006 120.0
TLS3_k127_1151564_4 Belongs to the anti-sigma-factor antagonist family K04749,K06378 - - 0.00001048 55.0
TLS3_k127_1154118_0 PFAM ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 539.0
TLS3_k127_1154118_1 CO dehydrogenase flavoprotein C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 312.0
TLS3_k127_1154118_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000000000000001255 155.0
TLS3_k127_1196107_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 3.953e-264 832.0
TLS3_k127_1196107_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 482.0
TLS3_k127_1196107_11 PFAM regulatory protein GntR HTH K07979 - - 0.000000000000000000000000000000000002908 141.0
TLS3_k127_1196107_12 - - - - 0.00000000000003201 76.0
TLS3_k127_1196107_2 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009489 441.0
TLS3_k127_1196107_3 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 340.0
TLS3_k127_1196107_4 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002281 281.0
TLS3_k127_1196107_5 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000249 230.0
TLS3_k127_1196107_6 SdpI/YhfL protein family - - - 0.000000000000000000000000000000000000000000000000000004492 197.0
TLS3_k127_1196107_7 organic phosphonate transmembrane transporter activity K02042 - - 0.00000000000000000000000000000000000000000000000000008195 208.0
TLS3_k127_1196107_8 phosphonoacetaldehyde hydrolase activity K01838,K07025 GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0044237,GO:0050308,GO:0050309 5.4.2.6 0.0000000000000000000000000000000000000000000000002303 183.0
TLS3_k127_1196107_9 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000004531 163.0
TLS3_k127_1220942_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 356.0
TLS3_k127_1220942_1 response regulator K11624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004531 248.0
TLS3_k127_1220942_2 signal transduction histidine kinase K11623 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000001517 220.0
TLS3_k127_1220942_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000003756 113.0
TLS3_k127_122105_0 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 431.0
TLS3_k127_122105_1 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 362.0
TLS3_k127_122105_2 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 309.0
TLS3_k127_122105_3 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 301.0
TLS3_k127_1235359_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 618.0
TLS3_k127_1235359_1 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 362.0
TLS3_k127_1235359_2 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 335.0
TLS3_k127_1235359_3 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004747 250.0
TLS3_k127_1235359_4 ThiS family K03636 - - 0.0000000004926 64.0
TLS3_k127_1257071_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 372.0
TLS3_k127_1257071_1 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000004877 160.0
TLS3_k127_1257071_2 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.00000000000000000000000000000000000000234 151.0
TLS3_k127_1257071_3 Protein of unknown function (DUF559) - - - 0.000000000000000000000000000007313 123.0
TLS3_k127_1257071_4 Bacterial DNA-binding protein - - - 0.00000000000000001053 87.0
TLS3_k127_1257071_5 Protein of unknown function (DUF3592) - - - 0.0000000696 59.0
TLS3_k127_1257071_6 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000001336 58.0
TLS3_k127_1257071_7 - - - - 0.0001715 53.0
TLS3_k127_1257071_8 Bardet-Biedl syndrome 2 protein homolog K16747 GO:0000003,GO:0000226,GO:0001085,GO:0001103,GO:0001501,GO:0001578,GO:0001894,GO:0001895,GO:0003006,GO:0003008,GO:0003012,GO:0003013,GO:0003018,GO:0003352,GO:0003356,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005815,GO:0005829,GO:0005856,GO:0005886,GO:0005902,GO:0005929,GO:0006810,GO:0006892,GO:0006893,GO:0006928,GO:0006936,GO:0006939,GO:0006996,GO:0007010,GO:0007017,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007288,GO:0007368,GO:0007369,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007600,GO:0007601,GO:0007610,GO:0008015,GO:0008104,GO:0008134,GO:0008150,GO:0009605,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009799,GO:0009855,GO:0009887,GO:0009888,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010468,GO:0010605,GO:0010629,GO:0014820,GO:0014824,GO:0014829,GO:0015031,GO:0015630,GO:0015833,GO:0016020,GO:0016043,GO:0016192,GO:0019221,GO:0019222,GO:0019953,GO:0021537,GO:0021543,GO:0021544,GO:0021756,GO:0021761,GO:0021766,GO:0021987,GO:0022412,GO:0022414,GO:0022607,GO:0023052,GO:0030030,GO:0030031,GO:0030154,GO:0030317,GO:0030534,GO:0030900,GO:0031090,GO:0031253,GO:0031514,GO:0031667,GO:0032095,GO:0032096,GO:0032098,GO:0032099,GO:0032101,GO:0032102,GO:0032104,GO:0032105,GO:0032107,GO:0032108,GO:0032400,GO:0032401,GO:0032402,GO:0032420,GO:0032421,GO:0032501,GO:0032502,GO:0032504,GO:0032870,GO:0032879,GO:0032886,GO:0032991,GO:0033036,GO:0033059,GO:0033210,GO:0033365,GO:0034097,GO:0034464,GO:0034613,GO:0035082,GO:0035150,GO:0035296,GO:0036064,GO:0038108,GO:0040008,GO:0040011,GO:0040012,GO:0040014,GO:0040015,GO:0040018,GO:0042221,GO:0042310,GO:0042311,GO:0042592,GO:0042886,GO:0042995,GO:0043001,GO:0043005,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043232,GO:0043473,GO:0044085,GO:0044320,GO:0044321,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044782,GO:0045184,GO:0045444,GO:0045494,GO:0045926,GO:0045927,GO:0046907,GO:0048193,GO:0048232,GO:0048468,GO:0048513,GO:0048515,GO:0048518,GO:0048519,GO:0048583,GO:0048585,GO:0048598,GO:0048609,GO:0048638,GO:0048639,GO:0048640,GO:0048731,GO:0048854,GO:0048856,GO:0048869,GO:0048870,GO:0048871,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050880,GO:0050896,GO:0050953,GO:0051093,GO:0051094,GO:0051179,GO:0051216,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051270,GO:0051640,GO:0051641,GO:0051648,GO:0051649,GO:0051650,GO:0051656,GO:0051674,GO:0051704,GO:0051716,GO:0051875,GO:0051877,GO:0051904,GO:0051905,GO:0060170,GO:0060249,GO:0060255,GO:0060271,GO:0060295,GO:0060296,GO:0060322,GO:0060632,GO:0061448,GO:0061512,GO:0061951,GO:0065007,GO:0065008,GO:0070121,GO:0070491,GO:0070727,GO:0070887,GO:0070925,GO:0071310,GO:0071345,GO:0071495,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0072659,GO:0090066,GO:0090150,GO:0097458,GO:0097722,GO:0097746,GO:0097755,GO:0097756,GO:0098588,GO:0098590,GO:0098858,GO:0098862,GO:0098876,GO:0120025,GO:0120031,GO:0120036,GO:0120038,GO:1902019,GO:1903441,GO:1905515,GO:1990778,GO:2000145 - 0.0002206 54.0
TLS3_k127_12585_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.472e-257 805.0
TLS3_k127_12585_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 2.429e-208 657.0
TLS3_k127_12585_10 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 328.0
TLS3_k127_12585_11 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 327.0
TLS3_k127_12585_12 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 325.0
TLS3_k127_12585_13 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 320.0
TLS3_k127_12585_14 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001324 278.0
TLS3_k127_12585_15 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000002301 257.0
TLS3_k127_12585_16 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000003829 254.0
TLS3_k127_12585_17 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000008629 229.0
TLS3_k127_12585_18 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000002761 233.0
TLS3_k127_12585_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002897 225.0
TLS3_k127_12585_2 Participates in both transcription termination and antitermination K02600 - - 2.618e-200 644.0
TLS3_k127_12585_20 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000001891 229.0
TLS3_k127_12585_21 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000009121 215.0
TLS3_k127_12585_22 - - - - 0.000000000000000000000000000000000000000000000000004008 185.0
TLS3_k127_12585_23 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000002709 184.0
TLS3_k127_12585_24 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000002856 166.0
TLS3_k127_12585_25 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000002274 158.0
TLS3_k127_12585_26 Domain of unknown function (DUF3597) - - - 0.000000000000000000000000000000000000002049 152.0
TLS3_k127_12585_27 PFAM regulatory protein LuxR - - - 0.00000000000000000000000000000000000001071 151.0
TLS3_k127_12585_28 Protein of unknown function (DUF448) K07742 - - 0.0000000000000000000000000000000000117 137.0
TLS3_k127_12585_29 - - - - 0.00000000000000000000000000000000005987 138.0
TLS3_k127_12585_3 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 467.0
TLS3_k127_12585_30 Protein of unknown function (DUF2089) - - - 0.000000000000000000000000000000002126 133.0
TLS3_k127_12585_31 extracellular polysaccharide biosynthetic process K13582 - - 0.000000000000000000000000000000006846 139.0
TLS3_k127_12585_32 NUDIX domain - - - 0.00000000000000000000000000001342 123.0
TLS3_k127_12585_33 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000001432 116.0
TLS3_k127_12585_34 LysM domain K21449,K22278 - 3.5.1.104 0.0000000000000000000000001033 116.0
TLS3_k127_12585_35 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000004349 98.0
TLS3_k127_12585_36 - - - - 0.0000000000000000000003342 109.0
TLS3_k127_12585_37 - K09932 - - 0.0000000000000000227 85.0
TLS3_k127_12585_38 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000002668 78.0
TLS3_k127_12585_39 lipolytic protein G-D-S-L family - - - 0.000000000000007835 85.0
TLS3_k127_12585_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 441.0
TLS3_k127_12585_41 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000002131 61.0
TLS3_k127_12585_5 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 417.0
TLS3_k127_12585_6 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 386.0
TLS3_k127_12585_7 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 329.0
TLS3_k127_12585_8 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 328.0
TLS3_k127_12585_9 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 331.0
TLS3_k127_1259220_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 524.0
TLS3_k127_1259220_1 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 421.0
TLS3_k127_1259220_2 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000329 234.0
TLS3_k127_1259220_3 Enoyl-CoA hydratase isomerase K15866 - 5.3.3.18 0.00000000005991 66.0
TLS3_k127_1291993_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 370.0
TLS3_k127_1291993_1 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.0000000000000000000000000000000000000000000000000000000000004418 222.0
TLS3_k127_1291993_2 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000005361 220.0
TLS3_k127_1291993_3 Domain of unknown function (DUF4445) - - - 0.0000000000001404 72.0
TLS3_k127_1313245_0 Aromatic amino acid lyase K01745 - 4.3.1.3 2.022e-217 681.0
TLS3_k127_1313245_1 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 424.0
TLS3_k127_1313245_2 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 383.0
TLS3_k127_1313245_3 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 367.0
TLS3_k127_1313245_4 dolichyl monophosphate biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005612 271.0
TLS3_k127_1313245_5 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009676 246.0
TLS3_k127_1313245_6 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000002204 121.0
TLS3_k127_1345850_0 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 470.0
TLS3_k127_1345850_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 309.0
TLS3_k127_1345850_10 23S rRNA-intervening sequence protein - - - 0.000601 43.0
TLS3_k127_1345850_2 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007701 295.0
TLS3_k127_1345850_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000002209 239.0
TLS3_k127_1345850_5 NurA - - - 0.000000000000000000000000000000000000000000000000000000000002746 223.0
TLS3_k127_1345850_6 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000000000000000000000000001759 216.0
TLS3_k127_1345850_7 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000005391 194.0
TLS3_k127_1345850_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000001663 184.0
TLS3_k127_1345850_9 acetyltransferase K01246 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 3.2.2.20 0.000000000000000000000000000000000000003273 152.0
TLS3_k127_134892_0 ABC transporter - - - 0.0 1289.0
TLS3_k127_134892_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 376.0
TLS3_k127_134892_10 FAD linked oxidase - - - 0.000000000000000000000000000000001765 136.0
TLS3_k127_134892_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000008215 89.0
TLS3_k127_134892_2 Berberine and berberine like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 368.0
TLS3_k127_134892_3 dihydrofolate reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 317.0
TLS3_k127_134892_4 DNA alkylation repair - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002568 260.0
TLS3_k127_134892_6 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000001831 206.0
TLS3_k127_134892_7 InterPro IPR014922 - - - 0.0000000000000000000000000000000000000000000000000004757 188.0
TLS3_k127_134892_8 Activator of Hsp90 ATPase - - - 0.00000000000000000000000000000000000000000000000001118 182.0
TLS3_k127_134892_9 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000001415 136.0
TLS3_k127_1454240_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 1.127e-200 633.0
TLS3_k127_1454240_1 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 358.0
TLS3_k127_1454240_2 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 296.0
TLS3_k127_1454240_3 Integral membrane sensor signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 297.0
TLS3_k127_1454240_4 Domain of unknown function (DUF4868) - - - 0.0000000000000000000000000000000000000000000098 173.0
TLS3_k127_1454240_5 - - - - 0.00000000000000000000001429 107.0
TLS3_k127_1454240_6 ABC-2 family transporter protein K01992 - - 0.00000000000007416 81.0
TLS3_k127_1476924_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 7.124e-199 634.0
TLS3_k127_1476924_1 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006093 563.0
TLS3_k127_1476924_10 Belongs to the peptidase S8 family K01361,K08652 - 3.4.21.110,3.4.21.96 0.000337 53.0
TLS3_k127_1476924_2 PFAM ABC transporter related K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 451.0
TLS3_k127_1476924_3 Protein of unknown function (DUF1385) K09153 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 368.0
TLS3_k127_1476924_4 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 338.0
TLS3_k127_1476924_5 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000000000000000000000000122 220.0
TLS3_k127_1476924_6 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000003404 218.0
TLS3_k127_1476924_7 OST-HTH/LOTUS domain - - - 0.000000000000000000000000002062 124.0
TLS3_k127_1476924_8 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000001403 96.0
TLS3_k127_1476924_9 Peptidase family M23 K08642 - - 0.0000000000000006304 92.0
TLS3_k127_1486248_0 L-arabinose isomerase activity K01804 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008733,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.3.1.4 7.343e-225 703.0
TLS3_k127_1486248_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 524.0
TLS3_k127_1486248_2 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000001073 225.0
TLS3_k127_1486248_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000002539 66.0
TLS3_k127_1515275_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 3.647e-209 660.0
TLS3_k127_1515275_1 SMART Elongator protein 3 MiaB NifB - - - 3.262e-208 656.0
TLS3_k127_1515275_10 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001451 258.0
TLS3_k127_1515275_11 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000001835 242.0
TLS3_k127_1515275_12 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000626 232.0
TLS3_k127_1515275_13 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000004343 213.0
TLS3_k127_1515275_14 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000001716 201.0
TLS3_k127_1515275_15 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000143 195.0
TLS3_k127_1515275_16 Ribosomal protein L11 methyltransferase (PrmA) K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000002716 172.0
TLS3_k127_1515275_17 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000001712 140.0
TLS3_k127_1515275_18 - - - - 0.00000000000000000000000000000002246 136.0
TLS3_k127_1515275_19 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000003343 132.0
TLS3_k127_1515275_2 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 602.0
TLS3_k127_1515275_20 cyclic nucleotide binding K10914 - - 0.00000000000000000000000007625 113.0
TLS3_k127_1515275_21 - - - - 0.000000000000000000000129 112.0
TLS3_k127_1515275_22 membrane - - - 0.000000000000000000007576 102.0
TLS3_k127_1515275_23 iron-sulfur cluster assembly - - - 0.00000000000000000001168 93.0
TLS3_k127_1515275_24 Polysaccharide biosynthesis protein - - - 0.00000000000004876 84.0
TLS3_k127_1515275_25 - - - - 0.0000000000002072 77.0
TLS3_k127_1515275_26 PFAM O-antigen polymerase - - - 0.0000009501 61.0
TLS3_k127_1515275_3 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 536.0
TLS3_k127_1515275_4 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 505.0
TLS3_k127_1515275_5 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 474.0
TLS3_k127_1515275_6 LysM domain K03046,K03641,K08642 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009065 485.0
TLS3_k127_1515275_7 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 399.0
TLS3_k127_1515275_8 transferase activity, transferring glycosyl groups K00694,K00786 - 2.4.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 370.0
TLS3_k127_1515275_9 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 346.0
TLS3_k127_152066_0 elongation factor Tu domain 2 protein K06207 - - 2.838e-283 882.0
TLS3_k127_152066_1 PFAM homogentisate 12-dioxygenase K00451 - 1.13.11.5 8.179e-203 636.0
TLS3_k127_152066_2 4-Hydroxyphenylpyruvate dioxygenase K00457,K16421 GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27,1.13.11.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 596.0
TLS3_k127_152066_3 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 307.0
TLS3_k127_152066_4 4-vinyl reductase, 4VR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 286.0
TLS3_k127_152066_5 PFAM Roadblock LC7 family protein K07131 - - 0.0000000000000000000000000000000000000000000000000000000008327 203.0
TLS3_k127_152066_6 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000002741 177.0
TLS3_k127_152066_7 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000005144 93.0
TLS3_k127_152066_8 cellulase activity K01218,K12132 - 2.7.11.1,3.2.1.78 0.000000006659 66.0
TLS3_k127_1522307_0 PFAM cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 493.0
TLS3_k127_1522307_1 PFAM Cytochrome bd ubiquinol oxidase, subunit II K00426 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 421.0
TLS3_k127_1522307_2 PFAM aminotransferase, class I and II K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 295.0
TLS3_k127_1522307_3 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 285.0
TLS3_k127_1522307_4 pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000002048 220.0
TLS3_k127_1522307_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000006328 207.0
TLS3_k127_1522307_6 transcriptional regulator - - - 0.0000000000000001423 85.0
TLS3_k127_1530507_0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 307.0
TLS3_k127_1530507_1 PFAM Diacylglycerol kinase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001308 247.0
TLS3_k127_1530507_2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000000000005 191.0
TLS3_k127_1530507_3 Acyl-transferase K00655,K00945 - 2.3.1.51,2.7.4.25 0.00000000000000000000000000000000000000000000000001042 188.0
TLS3_k127_1530507_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000002414 142.0
TLS3_k127_1544733_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009572 539.0
TLS3_k127_1544733_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000155 219.0
TLS3_k127_1544733_2 transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000000000000000000000000000002049 191.0
TLS3_k127_1544733_3 MafB19-like deaminase - - - 0.00000000000000000000000000005002 122.0
TLS3_k127_1544733_4 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000004345 85.0
TLS3_k127_1557143_0 Oxidoreductase - - - 7.76e-292 901.0
TLS3_k127_1557143_1 Thi4 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001414 261.0
TLS3_k127_15984_0 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000002442 247.0
TLS3_k127_15984_1 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.00000000000000000000000000000000000000000000000002105 186.0
TLS3_k127_15984_2 Pkd domain containing protein - - - 0.000000000000000000000000000000000005739 153.0
TLS3_k127_1692649_0 Belongs to the SEDS family - - - 1.223e-214 692.0
TLS3_k127_1692649_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 398.0
TLS3_k127_1692649_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 301.0
TLS3_k127_1692649_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000003555 234.0
TLS3_k127_1692649_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000001428 191.0
TLS3_k127_1692649_5 sh3 domain protein K01448 - 3.5.1.28 0.000000000000000000000000000005694 135.0
TLS3_k127_1692649_6 sh3 domain protein K01448 - 3.5.1.28 0.00000000000000000000000000002857 124.0
TLS3_k127_1692649_7 PFAM Forkhead-associated protein - - - 0.000000000000000000000000008246 121.0
TLS3_k127_1692649_8 PFAM Forkhead-associated protein - - - 0.00000000000000000000000009001 117.0
TLS3_k127_1692649_9 - - - - 0.0000001254 61.0
TLS3_k127_1723940_0 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 603.0
TLS3_k127_1723940_1 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 561.0
TLS3_k127_1723940_10 Acyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000002823 206.0
TLS3_k127_1723940_11 PFAM isochorismatase hydrolase - - - 0.000000000000000000000000000000000000000000000000000233 190.0
TLS3_k127_1723940_12 GNAT acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000002994 194.0
TLS3_k127_1723940_13 PFAM Fe-S metabolism associated SufE K02426 - - 0.00000000000000000000000000000000000001782 149.0
TLS3_k127_1723940_14 cellulose binding - - - 0.0000000000000000000000000000000000000245 158.0
TLS3_k127_1723940_15 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000002115 136.0
TLS3_k127_1723940_16 Transmembrane secretion effector K08225 - - 0.00000000000000000000000002155 110.0
TLS3_k127_1723940_17 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000000000000000000001565 108.0
TLS3_k127_1723940_18 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000004937 101.0
TLS3_k127_1723940_19 pathogenesis K01447,K21471 - 3.5.1.28 0.00000000001332 75.0
TLS3_k127_1723940_2 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 449.0
TLS3_k127_1723940_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 418.0
TLS3_k127_1723940_4 rRNA (adenine-N6,N6-)-dimethyltransferase activity K00561,K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182,2.1.1.184 0.000000000000000000000000000000000000000000000000000000000000000000000000000005998 270.0
TLS3_k127_1723940_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00177 - 1.2.7.1,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000196 248.0
TLS3_k127_1723940_6 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006367 253.0
TLS3_k127_1723940_7 RNase H K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000001325 241.0
TLS3_k127_1723940_8 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000000000001237 211.0
TLS3_k127_1723940_9 COG0656 Aldo keto reductases, related to diketogulonate reductase - - - 0.0000000000000000000000000000000000000000000000000000002805 203.0
TLS3_k127_1743764_0 DHH family K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 621.0
TLS3_k127_1743764_1 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 515.0
TLS3_k127_1743764_10 - - - - 0.000000000000000000005881 96.0
TLS3_k127_1743764_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 415.0
TLS3_k127_1743764_3 tryptophan 2,3-dioxygenase activity K00453,K03392 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11,4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 363.0
TLS3_k127_1743764_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000007249 235.0
TLS3_k127_1743764_5 - - - - 0.000000000000000000000000000000004163 137.0
TLS3_k127_1743764_6 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000001738 119.0
TLS3_k127_1743764_7 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000009404 121.0
TLS3_k127_1743764_8 transcriptional regulator K07729 - - 0.000000000000000000000000007658 112.0
TLS3_k127_1743764_9 Beta-eliminating lyase - - - 0.0000000000000000000004504 96.0
TLS3_k127_1744433_0 ABC transporter transmembrane region K06147,K06148 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008708 542.0
TLS3_k127_1744433_1 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000002251 68.0
TLS3_k127_1746853_0 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 512.0
TLS3_k127_1746853_1 Psort location Cytoplasmic, score 8.87 K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007271 488.0
TLS3_k127_1746853_2 Melibiase K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 491.0
TLS3_k127_1746853_3 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000001153 160.0
TLS3_k127_1746853_4 Transcription regulator K03718 - - 0.000000000000000000000000000000000002053 144.0
TLS3_k127_1746853_5 pterin-4-alpha-carbinolamine dehydratase K01724 GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 0.000000000000000005563 83.0
TLS3_k127_1746853_7 Belongs to the aldehyde dehydrogenase family K00146,K00151,K09472,K10217 - 1.2.1.32,1.2.1.39,1.2.1.60,1.2.1.85,1.2.1.99 0.000002438 49.0
TLS3_k127_1759906_0 Diaminopropionate ammonia-lyase K01751 - 4.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 496.0
TLS3_k127_1759906_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 457.0
TLS3_k127_1759906_2 histidinol dehydrogenase activity K00013,K14152 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009314,GO:0009411,GO:0009416,GO:0009507,GO:0009532,GO:0009536,GO:0009555,GO:0009570,GO:0009628,GO:0009987,GO:0016053,GO:0016462,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030145,GO:0032501,GO:0032502,GO:0034641,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0048229,GO:0048856,GO:0050896,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000534 426.0
TLS3_k127_1759906_3 Histidinol-phosphate aminotransferase K00817 GO:0000105,GO:0003674,GO:0003824,GO:0004400,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000001961 241.0
TLS3_k127_1759906_4 Tetratricopeptide repeat - - - 0.0000000000004096 84.0
TLS3_k127_1759906_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000009918 57.0
TLS3_k127_1765794_0 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 465.0
TLS3_k127_1765794_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 386.0
TLS3_k127_1765794_2 dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000775 275.0
TLS3_k127_1765794_3 PFAM Enoyl-CoA hydratase isomerase K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000002626 243.0
TLS3_k127_1765794_4 channel protein, hemolysin III family K11068 - - 0.000000000000000000000000000000000000000000000000000000003249 206.0
TLS3_k127_1765794_5 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000005748 139.0
TLS3_k127_1765794_6 family 25 K01185,K07273 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.17 0.000000000000000000000000000000003965 139.0
TLS3_k127_1765794_7 YsiA-like protein, C-terminal region - - - 0.00000000000000000000000000000003141 133.0
TLS3_k127_1765794_8 - - - - 0.000000000000000000000000000001272 129.0
TLS3_k127_1765794_9 gas vesicle protein - - - 0.0000000000000000001435 93.0
TLS3_k127_1767025_0 TIGRFAM amino acid adenylation domain - - - 0.0 1292.0
TLS3_k127_1767025_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 498.0
TLS3_k127_1767025_2 Thioesterase domain K01071 - 3.1.2.21 0.0000000000000000000000000000000000000000000000000000000000000008552 226.0
TLS3_k127_1767025_3 Belongs to the P-Pant transferase superfamily K06133 - - 0.00000000000000000000000000000000000000000000000000000000000001252 224.0
TLS3_k127_1767025_4 Protein of unknown function (DUF2723) - - - 0.00000008861 65.0
TLS3_k127_1767025_5 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.00004389 46.0
TLS3_k127_1781538_0 amino acid K03294 - - 3.123e-221 698.0
TLS3_k127_1781538_1 Beta-eliminating lyase - - - 1.936e-194 614.0
TLS3_k127_1781538_10 PRC-barrel domain - - - 0.000000000006578 74.0
TLS3_k127_1781538_2 metallophosphoesterase K07096,K07496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 373.0
TLS3_k127_1781538_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 338.0
TLS3_k127_1781538_4 PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000004589 246.0
TLS3_k127_1781538_5 - - - - 0.0000000000000000000000000000000000000000000000000000001844 203.0
TLS3_k127_1781538_6 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000002244 158.0
TLS3_k127_1781538_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.00000000000000000000000000000000000002353 146.0
TLS3_k127_1781538_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.000000000000000000000000000000001374 132.0
TLS3_k127_1781538_9 PRC-barrel domain - - - 0.0000000000000001527 88.0
TLS3_k127_1806102_0 Required for chromosome condensation and partitioning K03529 - - 1.889e-318 1013.0
TLS3_k127_1806102_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.376e-281 876.0
TLS3_k127_1806102_10 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000002922 237.0
TLS3_k127_1806102_11 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000000000000438 222.0
TLS3_k127_1806102_12 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000004523 162.0
TLS3_k127_1806102_13 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000001001 156.0
TLS3_k127_1806102_14 PFAM small multidrug resistance protein K11741,K18925 - - 0.00000000000000000000000000000000000000001797 155.0
TLS3_k127_1806102_15 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000001708 121.0
TLS3_k127_1806102_16 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000003243 122.0
TLS3_k127_1806102_17 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000006402 109.0
TLS3_k127_1806102_18 Protein of unknown function (DUF3592) - - - 0.0000000000006696 76.0
TLS3_k127_1806102_19 Protein kinase, cAMP-dependent, regulatory, type II, alpha K04739 GO:0000166,GO:0000902,GO:0000904,GO:0001664,GO:0001674,GO:0001932,GO:0001933,GO:0001934,GO:0003008,GO:0003014,GO:0003091,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0005886,GO:0005929,GO:0005952,GO:0006469,GO:0006928,GO:0006935,GO:0006950,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0007596,GO:0007599,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008150,GO:0008603,GO:0009410,GO:0009605,GO:0009611,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010720,GO:0014070,GO:0015630,GO:0016020,GO:0016043,GO:0017076,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0022008,GO:0022607,GO:0023052,GO:0030030,GO:0030104,GO:0030154,GO:0030182,GO:0030234,GO:0030291,GO:0030315,GO:0030534,GO:0030551,GO:0030552,GO:0030554,GO:0031175,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0031588,GO:0031625,GO:0031690,GO:0031698,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032870,GO:0032989,GO:0032990,GO:0032991,GO:0033673,GO:0033674,GO:0033762,GO:0034199,GO:0034236,GO:0035556,GO:0036094,GO:0040011,GO:0042060,GO:0042220,GO:0042221,GO:0042325,GO:0042326,GO:0042327,GO:0042330,GO:0042383,GO:0042493,GO:0042585,GO:0042592,GO:0042802,GO:0042803,GO:0042995,GO:0043073,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043279,GO:0043434,GO:0043549,GO:0043900,GO:0043902,GO:0043933,GO:0044085,GO:0044092,GO:0044093,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044853,GO:0045121,GO:0045471,GO:0045475,GO:0045595,GO:0045597,GO:0045787,GO:0045859,GO:0045860,GO:0045936,GO:0045937,GO:0046677,GO:0046983,GO:0048148,GO:0048149,GO:0048468,GO:0048471,GO:0048511,GO:0048512,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048871,GO:0048878,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050817,GO:0050878,GO:0050891,GO:0050896,GO:0051018,GO:0051094,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051259,GO:0051291,GO:0051338,GO:0051347,GO:0051348,GO:0051445,GO:0051446,GO:0051716,GO:0051726,GO:0060255,GO:0060281,GO:0060282,GO:0060284,GO:0060359,GO:0061564,GO:0061695,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071310,GO:0071375,GO:0071377,GO:0071417,GO:0071495,GO:0071840,GO:0071900,GO:0071901,GO:0071944,GO:0072347,GO:0080090,GO:0090068,GO:0097159,GO:0097305,GO:0097332,GO:0097338,GO:0097367,GO:0097485,GO:0097546,GO:0098589,GO:0098590,GO:0098772,GO:0098805,GO:0098857,GO:0120025,GO:0120036,GO:0120038,GO:0120039,GO:1900193,GO:1900195,GO:1901265,GO:1901363,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902494,GO:1902911,GO:1903429,GO:1903431,GO:1903538,GO:1904146,GO:1905879,GO:1905881,GO:1990234,GO:2000241,GO:2000243,GO:2000479,GO:2000480 - 0.0000006915 57.0
TLS3_k127_1806102_2 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 586.0
TLS3_k127_1806102_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 379.0
TLS3_k127_1806102_4 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 380.0
TLS3_k127_1806102_5 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 360.0
TLS3_k127_1806102_6 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 353.0
TLS3_k127_1806102_7 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 301.0
TLS3_k127_1806102_8 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 288.0
TLS3_k127_1806102_9 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003583 250.0
TLS3_k127_1827711_0 binding-protein-dependent transport systems inner membrane component K02011 - - 1.055e-238 748.0
TLS3_k127_1827711_1 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 462.0
TLS3_k127_1827711_2 extracellular solute-binding protein, family 1 K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 374.0
TLS3_k127_1827711_3 methylamine metabolic process K03885,K15977 - 1.6.99.3 0.000000000000000000000000000000000007237 141.0
TLS3_k127_1827711_4 transcriptional regulator - - - 0.000000000000000000000000000000201 131.0
TLS3_k127_1827711_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.000000000000000000004524 96.0
TLS3_k127_1827711_6 Chromatin associated protein KTI12 - - - 0.00000000002955 70.0
TLS3_k127_1828784_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.716e-309 964.0
TLS3_k127_1828784_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 2.021e-221 696.0
TLS3_k127_1828784_10 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 304.0
TLS3_k127_1828784_11 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001395 261.0
TLS3_k127_1828784_12 PFAM Sodium Bile acid symporter family K03453 - - 0.0000000000000000000000000000000000000000000000000000000000001126 225.0
TLS3_k127_1828784_13 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000003678 213.0
TLS3_k127_1828784_14 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000001364 180.0
TLS3_k127_1828784_15 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000001414 176.0
TLS3_k127_1828784_16 MaoC domain protein dehydratase K00634 - 2.3.1.19 0.00000000000000000000000000000000000000009979 154.0
TLS3_k127_1828784_17 - - - - 0.00000000000000000000000000000000004306 143.0
TLS3_k127_1828784_18 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000003871 134.0
TLS3_k127_1828784_19 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000004857 112.0
TLS3_k127_1828784_2 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 5.968e-204 647.0
TLS3_k127_1828784_20 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000003167 89.0
TLS3_k127_1828784_22 - - - - 0.00009202 51.0
TLS3_k127_1828784_3 PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein K00341 - 1.6.5.3 2.783e-194 616.0
TLS3_k127_1828784_4 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 604.0
TLS3_k127_1828784_5 Proton-conducting membrane transporter K00342,K05575 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 473.0
TLS3_k127_1828784_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 441.0
TLS3_k127_1828784_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 437.0
TLS3_k127_1828784_8 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 374.0
TLS3_k127_1828784_9 transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 362.0
TLS3_k127_1837023_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001762 291.0
TLS3_k127_1837023_1 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007436 285.0
TLS3_k127_1837023_2 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003507 260.0
TLS3_k127_1837023_3 Ig-like domain from next to BRCA1 gene - - - 0.000000001491 70.0
TLS3_k127_1837023_4 Protein of unknown function (DUF1706) - - - 0.0000009332 54.0
TLS3_k127_1845055_0 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 377.0
TLS3_k127_1845055_1 SMART PDZ DHR GLGF domain protein K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 299.0
TLS3_k127_1845055_2 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000007808 225.0
TLS3_k127_1845055_3 sigma-70 region 2 domain protein K03088 - - 0.00000000000000000000000000000000000000000000000002176 186.0
TLS3_k127_1845055_4 CAAX protease self-immunity - - - 0.0000000000000000000000000000003953 134.0
TLS3_k127_184646_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 7.898e-256 799.0
TLS3_k127_184646_1 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 336.0
TLS3_k127_184646_2 ABC transporter transmembrane region K06147,K06148 - - 0.00004156 46.0
TLS3_k127_1848972_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 7.302e-220 700.0
TLS3_k127_1848972_1 PFAM Cytochrome C assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 527.0
TLS3_k127_1848972_10 Peptidase MA superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000101 242.0
TLS3_k127_1848972_11 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000000000004459 208.0
TLS3_k127_1848972_12 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000005939 172.0
TLS3_k127_1848972_13 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000000000538 154.0
TLS3_k127_1848972_14 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000000000000001338 154.0
TLS3_k127_1848972_15 Lysin motif - - - 0.00000000000000000000000000000001336 139.0
TLS3_k127_1848972_16 zinc-ribbon domain - - - 0.000000000000000000000000000006236 124.0
TLS3_k127_1848972_3 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 430.0
TLS3_k127_1848972_4 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 402.0
TLS3_k127_1848972_5 PFAM ABC transporter related K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 330.0
TLS3_k127_1848972_6 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 331.0
TLS3_k127_1848972_7 PFAM Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 290.0
TLS3_k127_1848972_8 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001252 275.0
TLS3_k127_1848972_9 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002529 283.0
TLS3_k127_1868819_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1119.0
TLS3_k127_1868819_1 Sulfate permease family K03321 - - 1.295e-262 818.0
TLS3_k127_1868819_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000259 218.0
TLS3_k127_1868819_11 - - - - 0.000000000000000000000000000000000000000000000000000000002162 204.0
TLS3_k127_1868819_12 LysM domain - - - 0.00000000000000000000000000000000000000000000000000006934 198.0
TLS3_k127_1868819_14 enterobactin catabolic process K07214 - - 0.000000000000000000000000000000000000000000000116 179.0
TLS3_k127_1868819_15 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000001924 169.0
TLS3_k127_1868819_16 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000004465 145.0
TLS3_k127_1868819_17 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000001396 134.0
TLS3_k127_1868819_18 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000001568 129.0
TLS3_k127_1868819_19 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000002559 108.0
TLS3_k127_1868819_2 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 2.19e-206 647.0
TLS3_k127_1868819_20 PFAM HEPN domain - - - 0.00000000000000000000006738 104.0
TLS3_k127_1868819_21 Nucleotidyltransferase domain K07076 - - 0.000000000000000000000411 99.0
TLS3_k127_1868819_22 mercury ion transmembrane transporter activity K07213 - - 0.0000000000000000002832 89.0
TLS3_k127_1868819_23 mercury ion transmembrane transporter activity K07213 - - 0.000000000000000004216 87.0
TLS3_k127_1868819_24 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.000000000000000009336 88.0
TLS3_k127_1868819_26 - - - - 0.00000000001472 70.0
TLS3_k127_1868819_27 reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000001316 64.0
TLS3_k127_1868819_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 505.0
TLS3_k127_1868819_30 - - - - 0.00005736 46.0
TLS3_k127_1868819_31 metal ion permease K07089 - - 0.0001945 46.0
TLS3_k127_1868819_4 PFAM amidohydrolase K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 432.0
TLS3_k127_1868819_5 Biogenesis protein K02275,K09792,K17686 - 1.9.3.1,3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 380.0
TLS3_k127_1868819_6 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 376.0
TLS3_k127_1868819_7 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008912 362.0
TLS3_k127_1868819_8 TIGRFAM RarD protein, DMT superfamily transporter K05786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 346.0
TLS3_k127_1868819_9 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 294.0
TLS3_k127_187410_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1212.0
TLS3_k127_187410_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 2.847e-217 688.0
TLS3_k127_187410_2 methyltransferase activity - - - 0.00000000001838 64.0
TLS3_k127_187410_3 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00005303 47.0
TLS3_k127_187410_4 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0006651 42.0
TLS3_k127_1891258_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 423.0
TLS3_k127_1891258_1 PFAM IstB domain protein ATP-binding protein K02315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 406.0
TLS3_k127_1891258_2 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000000000000005626 212.0
TLS3_k127_1891258_3 isochorismatase - - - 0.000000000000000000000000000000000000000000004424 174.0
TLS3_k127_1891258_4 TIGRFAM primosome, DnaD subunit - - - 0.00000000000000000000000008203 115.0
TLS3_k127_1893597_0 PBP superfamily domain K03750,K07219 - 2.10.1.1 9.859e-283 884.0
TLS3_k127_1893597_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 3.026e-195 617.0
TLS3_k127_1893597_10 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000008957 207.0
TLS3_k127_1893597_11 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000003412 176.0
TLS3_k127_1893597_12 CAAX protease self-immunity K01266,K07052 - 3.4.11.19 0.0000000000000000000000000000006287 136.0
TLS3_k127_1893597_13 PFAM Transglycosylase associated protein - - - 0.000000000000000000000000249 108.0
TLS3_k127_1893597_14 rRNA binding - - - 0.0000000000000001795 86.0
TLS3_k127_1893597_15 COG2010 Cytochrome c, mono- and diheme variants K07243 - - 0.000000000000006032 80.0
TLS3_k127_1893597_16 Histidine kinase - - - 0.0000000000001228 76.0
TLS3_k127_1893597_2 transposase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 569.0
TLS3_k127_1893597_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 468.0
TLS3_k127_1893597_4 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008147 431.0
TLS3_k127_1893597_5 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 398.0
TLS3_k127_1893597_6 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 325.0
TLS3_k127_1893597_7 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006635 284.0
TLS3_k127_1893597_9 Fumarylacetoacetase K01555 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000008724 203.0
TLS3_k127_1912554_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1341.0
TLS3_k127_1912554_1 NTF2-like N-terminal transpeptidase domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000069 579.0
TLS3_k127_1912554_10 membrane transporter protein K07090 - - 0.000000000000000000000000000000262 124.0
TLS3_k127_1912554_11 4Fe-4S dicluster domain - - - 0.0000000000000000003167 92.0
TLS3_k127_1912554_12 PFAM Transglycosylase-associated protein - - - 0.000000000000000002529 88.0
TLS3_k127_1912554_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 387.0
TLS3_k127_1912554_3 PFAM NMT1 THI5 like domain protein K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 349.0
TLS3_k127_1912554_4 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 344.0
TLS3_k127_1912554_5 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 313.0
TLS3_k127_1912554_6 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003898 284.0
TLS3_k127_1912554_7 PFAM binding-protein-dependent transport systems inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003865 268.0
TLS3_k127_1912554_8 PFAM Maf family protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000008785 228.0
TLS3_k127_1912554_9 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000001844 196.0
TLS3_k127_192937_0 Phosphoribosyl transferase domain K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 302.0
TLS3_k127_192937_1 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000000000000000000003692 191.0
TLS3_k127_192937_2 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.000000000000000000000000000000000000000000003062 171.0
TLS3_k127_192937_3 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000003143 133.0
TLS3_k127_194193_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K01782,K07516 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 623.0
TLS3_k127_194193_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000004493 102.0
TLS3_k127_1962376_0 Selenocysteine-specific translation elongation factor K03833 - - 1.935e-239 755.0
TLS3_k127_1962376_1 Short-chain dehydrogenase reductase SDR - - - 4.471e-238 751.0
TLS3_k127_1962376_10 Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 394.0
TLS3_k127_1962376_11 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 371.0
TLS3_k127_1962376_12 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 329.0
TLS3_k127_1962376_13 Proton-conducting membrane transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 297.0
TLS3_k127_1962376_14 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002617 286.0
TLS3_k127_1962376_15 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001059 267.0
TLS3_k127_1962376_16 Fe-S protein K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006615 252.0
TLS3_k127_1962376_17 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006869 257.0
TLS3_k127_1962376_18 Beta-lactamase K01256,K17836 - 3.4.11.2,3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000001026 240.0
TLS3_k127_1962376_19 exodeoxyribonuclease I activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001325 231.0
TLS3_k127_1962376_2 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 477.0
TLS3_k127_1962376_21 Protein of unknown function (DUF3048) C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000031 240.0
TLS3_k127_1962376_22 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000002732 210.0
TLS3_k127_1962376_23 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000000006374 189.0
TLS3_k127_1962376_24 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000007055 160.0
TLS3_k127_1962376_25 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000013 158.0
TLS3_k127_1962376_26 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000009061 145.0
TLS3_k127_1962376_27 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000004441 128.0
TLS3_k127_1962376_28 PFAM response regulator receiver K07657,K07659,K07664,K11329 - - 0.00000000000000000001704 96.0
TLS3_k127_1962376_29 - - - - 0.000000000000000001344 89.0
TLS3_k127_1962376_3 CoA binding domain K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 469.0
TLS3_k127_1962376_4 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 439.0
TLS3_k127_1962376_5 Pyridoxal-phosphate dependent enzyme K17950 - 4.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 421.0
TLS3_k127_1962376_6 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 432.0
TLS3_k127_1962376_7 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 427.0
TLS3_k127_1962376_8 PFAM Methicillin resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006239 418.0
TLS3_k127_1962376_9 PFAM Methicillin resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 407.0
TLS3_k127_1969323_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 2.06e-253 792.0
TLS3_k127_1969323_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 376.0
TLS3_k127_1969323_10 FAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000003127 231.0
TLS3_k127_1969323_11 Domain of unknown function (DUF1980) - - - 0.000000000000000000000000000000000000000000000000000007674 198.0
TLS3_k127_1969323_12 Tetratricopeptide repeat protein - - - 0.000000000000000000000000000000000000000000000001026 182.0
TLS3_k127_1969323_13 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000004976 175.0
TLS3_k127_1969323_14 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000158 150.0
TLS3_k127_1969323_15 Protein of unknown function (DUF1304) K08987 - - 0.000000000000000000000000000000000000002716 149.0
TLS3_k127_1969323_17 PFAM Rhodanese domain protein - - - 0.000000000000000000000000006442 116.0
TLS3_k127_1969323_18 Belongs to the anti-sigma-factor antagonist family - - - 0.000003464 56.0
TLS3_k127_1969323_19 Belongs to the anti-sigma-factor antagonist family - - - 0.00001566 52.0
TLS3_k127_1969323_2 ABC-3 protein K09819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 334.0
TLS3_k127_1969323_20 WD40-like Beta Propeller Repeat - - - 0.0001963 54.0
TLS3_k127_1969323_3 PFAM ABC transporter related K09820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 326.0
TLS3_k127_1969323_4 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 308.0
TLS3_k127_1969323_5 COG2211 Na melibiose symporter and related K03292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 297.0
TLS3_k127_1969323_6 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001172 290.0
TLS3_k127_1969323_7 phosphatidylinositol kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002466 265.0
TLS3_k127_1969323_8 Belongs to the bacterial solute-binding protein 9 family K02077,K09818 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006016 262.0
TLS3_k127_1969323_9 Protein of unknown function (DUF3090) - - - 0.00000000000000000000000000000000000000000000000000000000000000003716 226.0
TLS3_k127_1978637_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.369e-225 720.0
TLS3_k127_1978637_1 extracellular solute-binding protein, family 3 K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 490.0
TLS3_k127_1978637_2 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 431.0
TLS3_k127_1978637_3 Binding-protein-dependent transport system inner membrane component K09970 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 346.0
TLS3_k127_1978637_4 Aminoacyl-tRNA editing domain K03976 - - 0.000000000000000000000000000000000000000000000002644 178.0
TLS3_k127_1978637_5 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000009894 69.0
TLS3_k127_1978637_6 PFAM ABC transporter related K09972 - - 0.00000002137 56.0
TLS3_k127_2016937_0 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 496.0
TLS3_k127_2016937_1 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 478.0
TLS3_k127_2016937_2 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 461.0
TLS3_k127_2016937_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 312.0
TLS3_k127_2016937_4 Alpha beta hydrolase K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001997 281.0
TLS3_k127_2043579_0 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 492.0
TLS3_k127_2043579_1 Belongs to the cysteine synthase cystathionine beta- synthase family K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 352.0
TLS3_k127_2043579_2 Domain of unknown function (DUF4395) - - - 0.00000000000000000000000000000000000000000000001053 177.0
TLS3_k127_2043579_3 JAB/MPN domain K21140 - 3.13.1.6 0.000000000000000000000000001113 117.0
TLS3_k127_2043579_4 COG0526, thiol-disulfide isomerase and thioredoxins K03671 - - 0.000000000000000000000000003202 119.0
TLS3_k127_2043579_5 ThiS family K03636 - - 0.000000000000000000000002974 104.0
TLS3_k127_2043579_6 ThiS family K03636 - - 0.000000000000000000007812 94.0
TLS3_k127_2053876_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 480.0
TLS3_k127_2053876_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008582 462.0
TLS3_k127_2053876_10 - - - - 0.0000001769 61.0
TLS3_k127_2053876_11 Protein tyrosine kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000001013 52.0
TLS3_k127_2053876_2 Stage II sporulation K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 347.0
TLS3_k127_2053876_3 PFAM deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 316.0
TLS3_k127_2053876_4 adenosylhomocysteine nucleosidase activity K01239,K01243,K03716 - 3.2.2.1,3.2.2.9,4.1.99.14 0.0000000000000000000000000000000000000000000001289 180.0
TLS3_k127_2053876_5 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000008985 161.0
TLS3_k127_2053876_6 - - - - 0.000000000000000000000000000000000008316 149.0
TLS3_k127_2053876_7 ABC transporter K06158 - - 0.00000000000000000000000000000000001959 137.0
TLS3_k127_2053876_8 Chromosome 6 open reading frame 106 - GO:0000407,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005776,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016236,GO:0032182,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0061919 - 0.0000000000000105 82.0
TLS3_k127_2053876_9 filamentous hemagglutinin family N-terminal domain - - - 0.00000000009718 74.0
TLS3_k127_2054061_0 Protein of unknown function, DUF255 K06888 - - 6.959e-216 688.0
TLS3_k127_2054061_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 496.0
TLS3_k127_2054061_10 Protein tyrosine kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000003188 52.0
TLS3_k127_2054061_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 397.0
TLS3_k127_2054061_3 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 331.0
TLS3_k127_2054061_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006317 247.0
TLS3_k127_2054061_5 PFAM MgtC SapB transporter K07507 - - 0.00000000000000000000000000000000000000000000436 171.0
TLS3_k127_2054061_7 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000009871 120.0
TLS3_k127_2054061_8 WD40-like Beta Propeller K03641 - - 0.0000000000000000000000149 119.0
TLS3_k127_2070929_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.254e-253 813.0
TLS3_k127_2070929_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 8.902e-218 689.0
TLS3_k127_2070929_10 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 320.0
TLS3_k127_2070929_11 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 308.0
TLS3_k127_2070929_12 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 308.0
TLS3_k127_2070929_13 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 297.0
TLS3_k127_2070929_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 297.0
TLS3_k127_2070929_15 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001256 283.0
TLS3_k127_2070929_16 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005013 273.0
TLS3_k127_2070929_17 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007435 272.0
TLS3_k127_2070929_18 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002558 259.0
TLS3_k127_2070929_19 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002157 251.0
TLS3_k127_2070929_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 543.0
TLS3_k127_2070929_20 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000005949 238.0
TLS3_k127_2070929_21 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000009363 229.0
TLS3_k127_2070929_22 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000001661 229.0
TLS3_k127_2070929_23 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000009162 220.0
TLS3_k127_2070929_24 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001336 219.0
TLS3_k127_2070929_25 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000001695 216.0
TLS3_k127_2070929_26 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001073 213.0
TLS3_k127_2070929_27 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000000000002748 208.0
TLS3_k127_2070929_28 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000004162 206.0
TLS3_k127_2070929_29 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000002373 189.0
TLS3_k127_2070929_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004173 500.0
TLS3_k127_2070929_30 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000001235 187.0
TLS3_k127_2070929_31 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000001021 177.0
TLS3_k127_2070929_32 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000085 171.0
TLS3_k127_2070929_33 - - - - 0.0000000000000000000000000000000000000000000002374 175.0
TLS3_k127_2070929_34 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000005431 158.0
TLS3_k127_2070929_35 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000001098 156.0
TLS3_k127_2070929_36 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000336 151.0
TLS3_k127_2070929_37 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000005518 147.0
TLS3_k127_2070929_38 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000000001192 123.0
TLS3_k127_2070929_39 - - - - 0.0000000000000000000000000000282 119.0
TLS3_k127_2070929_4 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 522.0
TLS3_k127_2070929_40 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000003173 121.0
TLS3_k127_2070929_41 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000007638 112.0
TLS3_k127_2070929_42 Alpha beta hydrolase K00433 - 1.11.1.10 0.00000000000000000002426 104.0
TLS3_k127_2070929_43 Domain of unknown function (DUF1992) - - - 0.00000000000000000009281 95.0
TLS3_k127_2070929_44 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000002668 78.0
TLS3_k127_2070929_45 Ribosomal protein L30p/L7e K02907 - - 0.0000000000000003878 81.0
TLS3_k127_2070929_46 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000002643 75.0
TLS3_k127_2070929_47 Ribosomal protein L36 K02919 - - 0.0000000000005248 69.0
TLS3_k127_2070929_5 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 469.0
TLS3_k127_2070929_6 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 372.0
TLS3_k127_2070929_7 Radical SAM K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 379.0
TLS3_k127_2070929_8 TIGRFAM MazG family protein K02499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 351.0
TLS3_k127_2070929_9 HhH-GPD family K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 327.0
TLS3_k127_208277_0 PFAM Endonuclease Exonuclease phosphatase K07004 - - 0.0 1202.0
TLS3_k127_208277_1 PFAM magnesium chelatase ChlI subunit K07391 - - 2.038e-226 711.0
TLS3_k127_208277_2 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 447.0
TLS3_k127_208277_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 442.0
TLS3_k127_208277_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 339.0
TLS3_k127_208277_5 Redoxin K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 296.0
TLS3_k127_208277_6 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001629 277.0
TLS3_k127_208277_7 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000004222 262.0
TLS3_k127_208277_8 AzlC protein - - - 0.000000000000000000000000000000000000000000000000000000002514 205.0
TLS3_k127_208277_9 cellulase activity K07004 - - 0.00000000000000000000000000000000000254 160.0
TLS3_k127_2095850_0 Elongator protein 3, MiaB family, Radical SAM - - - 4.379e-263 827.0
TLS3_k127_2095850_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.059e-249 778.0
TLS3_k127_2095850_10 NUDIX domain - - - 0.00000000000000000000005491 105.0
TLS3_k127_2095850_11 protein conserved in bacteria - - - 0.0000002648 63.0
TLS3_k127_2095850_12 NlpC/P60 family - - - 0.000004333 59.0
TLS3_k127_2095850_13 Protein of unknown function (DUF1706) - - - 0.0006407 49.0
TLS3_k127_2095850_2 Cell division protein FtsA K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 346.0
TLS3_k127_2095850_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 336.0
TLS3_k127_2095850_4 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 316.0
TLS3_k127_2095850_5 Protease prsW family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006321 286.0
TLS3_k127_2095850_6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001076 267.0
TLS3_k127_2095850_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000001499 192.0
TLS3_k127_2095850_8 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.0000000000000000000000000000000000000000000000004858 183.0
TLS3_k127_2095850_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000007111 177.0
TLS3_k127_2131538_0 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 360.0
TLS3_k127_2131538_1 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 334.0
TLS3_k127_2131538_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000002794 61.0
TLS3_k127_2155896_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 596.0
TLS3_k127_2155896_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 578.0
TLS3_k127_2155896_2 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 318.0
TLS3_k127_2155896_3 Phosphoribosyl transferase domain K07101 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007821 240.0
TLS3_k127_2155896_4 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.0000000000000000000000000000000000000009216 153.0
TLS3_k127_2155896_5 Transcriptional regulator, Crp Fnr family K10914,K21563 - - 0.00000000000000000000000000000000002379 145.0
TLS3_k127_2155896_6 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000001367 97.0
TLS3_k127_2155896_7 - - - - 0.000000000000000009268 94.0
TLS3_k127_2155896_8 - - - - 0.0000000002476 67.0
TLS3_k127_2155896_9 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0001859 46.0
TLS3_k127_2179790_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 4.235e-228 718.0
TLS3_k127_2179790_1 PFAM peptidase M4 thermolysin K08603 - 3.4.24.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 462.0
TLS3_k127_2179790_2 - - - - 0.00000000000005435 76.0
TLS3_k127_2194019_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 6.166e-231 739.0
TLS3_k127_2194019_1 UDP-N-acetylglucosamine 2-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 590.0
TLS3_k127_2194019_10 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000005433 199.0
TLS3_k127_2194019_11 Sulfotransferase domain - - - 0.00000000000000000000000000000000002885 145.0
TLS3_k127_2194019_13 Universal stress protein - - - 0.00002499 52.0
TLS3_k127_2194019_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 451.0
TLS3_k127_2194019_3 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 445.0
TLS3_k127_2194019_4 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 437.0
TLS3_k127_2194019_5 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 426.0
TLS3_k127_2194019_6 TIGRFAM LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 339.0
TLS3_k127_2194019_7 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 306.0
TLS3_k127_2194019_8 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000199 214.0
TLS3_k127_2194019_9 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000002176 205.0
TLS3_k127_2194218_0 TIGRFAM cysteine desulfurase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006728 304.0
TLS3_k127_2194218_1 TIGRFAM cysteine desulfurase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 291.0
TLS3_k127_2194218_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000002018 211.0
TLS3_k127_2194218_3 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000002284 205.0
TLS3_k127_2194218_4 Universal stress protein - - - 0.00000000000000000000000000000000003216 139.0
TLS3_k127_220236_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008426 476.0
TLS3_k127_220236_1 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009848 362.0
TLS3_k127_220236_2 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 338.0
TLS3_k127_220236_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000005976 265.0
TLS3_k127_220236_4 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000002119 197.0
TLS3_k127_220236_5 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000000000331 111.0
TLS3_k127_220236_6 - - - - 0.0000000000000000000503 100.0
TLS3_k127_220236_7 O-Antigen ligase - - - 0.00000000007159 75.0
TLS3_k127_220236_8 helix-turn-helix domain protein - - - 0.0000001072 62.0
TLS3_k127_2227990_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1479.0
TLS3_k127_2227990_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 1.419e-254 814.0
TLS3_k127_2227990_10 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 329.0
TLS3_k127_2227990_11 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 336.0
TLS3_k127_2227990_12 TIGRFAM Methylated-DNA- protein -cysteine S-methyltransferase, DNA binding K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 312.0
TLS3_k127_2227990_13 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 294.0
TLS3_k127_2227990_14 lipid binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 288.0
TLS3_k127_2227990_15 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001479 272.0
TLS3_k127_2227990_16 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000002442 281.0
TLS3_k127_2227990_17 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006857 244.0
TLS3_k127_2227990_18 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000272 245.0
TLS3_k127_2227990_19 chloramphenicol K18554 - - 0.00000000000000000000000000000000001068 143.0
TLS3_k127_2227990_2 SMART Adenylyl cyclase class-3 4 guanylyl cyclase - - - 1.329e-250 822.0
TLS3_k127_2227990_20 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000003762 102.0
TLS3_k127_2227990_21 peroxiredoxin activity - - - 0.0000000000000000000003683 104.0
TLS3_k127_2227990_23 Peptidoglycan binding domain - - - 0.000000001139 68.0
TLS3_k127_2227990_24 Involved in the tonB-independent uptake of proteins K01771 - 4.6.1.13 0.000008368 57.0
TLS3_k127_2227990_3 Belongs to the peptidase S41A family - - - 1.344e-238 763.0
TLS3_k127_2227990_4 PFAM amine oxidase K00274 - 1.4.3.4 2.526e-236 737.0
TLS3_k127_2227990_5 SMART AAA ATPase - - - 1.319e-215 676.0
TLS3_k127_2227990_6 tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 564.0
TLS3_k127_2227990_7 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 571.0
TLS3_k127_2227990_8 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 541.0
TLS3_k127_2227990_9 signal peptide processing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 439.0
TLS3_k127_2268804_0 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 534.0
TLS3_k127_2268804_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 511.0
TLS3_k127_2268804_2 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 399.0
TLS3_k127_2268804_3 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 348.0
TLS3_k127_2268804_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 347.0
TLS3_k127_2268804_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 347.0
TLS3_k127_2268804_6 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 332.0
TLS3_k127_2268804_7 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.0000000000000000000000000000000000000000000000000000005258 205.0
TLS3_k127_2268804_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000005379 153.0
TLS3_k127_2322550_0 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K12528 - - 0.0 1407.0
TLS3_k127_233266_0 Serine Threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 479.0
TLS3_k127_233266_1 CHASE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 394.0
TLS3_k127_233266_2 PFAM HD domain - - - 0.000000000000000000000000000000000000000000003402 190.0
TLS3_k127_2388246_0 Permease family K02824 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 487.0
TLS3_k127_2388246_1 CO dehydrogenase flavoprotein C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003278 282.0
TLS3_k127_2388246_2 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006414 282.0
TLS3_k127_2388246_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000001753 239.0
TLS3_k127_2388246_4 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.000000000000000000000002197 108.0
TLS3_k127_2396477_0 Heat shock 70 kDa protein K04043 - - 8.056e-315 974.0
TLS3_k127_2396477_1 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 587.0
TLS3_k127_2396477_10 ATP-dependent peptidase activity K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 297.0
TLS3_k127_2396477_11 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 289.0
TLS3_k127_2396477_12 PFAM glycosyl transferase, family 28 K05841 - 2.4.1.173 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001247 291.0
TLS3_k127_2396477_13 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000009016 269.0
TLS3_k127_2396477_14 PFAM methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000004433 257.0
TLS3_k127_2396477_15 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001288 267.0
TLS3_k127_2396477_16 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002356 250.0
TLS3_k127_2396477_17 PFAM acyltransferase 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000289 242.0
TLS3_k127_2396477_18 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000521 162.0
TLS3_k127_2396477_19 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000006035 173.0
TLS3_k127_2396477_2 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 574.0
TLS3_k127_2396477_20 YbaB/EbfC DNA-binding family K06187,K09747 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000003496 148.0
TLS3_k127_2396477_21 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000000001648 141.0
TLS3_k127_2396477_22 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000007155 137.0
TLS3_k127_2396477_23 Amidohydrolase family - - - 0.00000000000000000000000000000004439 126.0
TLS3_k127_2396477_24 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000003951 105.0
TLS3_k127_2396477_25 - - - - 0.000000001078 61.0
TLS3_k127_2396477_26 competence protein COMEC K02238 - - 0.00000005216 61.0
TLS3_k127_2396477_27 acetyltransferase - - - 0.0000001604 54.0
TLS3_k127_2396477_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 503.0
TLS3_k127_2396477_4 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 426.0
TLS3_k127_2396477_5 peptidase M24 K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 399.0
TLS3_k127_2396477_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 395.0
TLS3_k127_2396477_7 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 372.0
TLS3_k127_2396477_8 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 327.0
TLS3_k127_2396477_9 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 344.0
TLS3_k127_242085_0 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 379.0
TLS3_k127_242085_1 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 376.0
TLS3_k127_242085_2 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 334.0
TLS3_k127_242085_3 peptidase dimerisation domain protein K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 291.0
TLS3_k127_242085_4 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000001169 240.0
TLS3_k127_242085_5 PFAM Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000103 241.0
TLS3_k127_242085_6 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000002042 217.0
TLS3_k127_248040_0 histidine kinase A domain protein - - - 0.0 1218.0
TLS3_k127_248040_1 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 400.0
TLS3_k127_248040_2 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 357.0
TLS3_k127_248040_3 FIST N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007744 275.0
TLS3_k127_248040_4 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000001525 165.0
TLS3_k127_248040_5 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.0000000000000000000000000000000000000000015 160.0
TLS3_k127_248040_6 Sporulation and spore germination - - - 0.00003945 54.0
TLS3_k127_2502561_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 386.0
TLS3_k127_2502561_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000003195 163.0
TLS3_k127_2502561_2 cellular response to heat K09807 - - 0.0000000000000000000000000000000004205 139.0
TLS3_k127_2502561_3 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000008331 78.0
TLS3_k127_2502561_4 ABC-2 family transporter protein - - - 0.0000000001824 64.0
TLS3_k127_250968_0 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 3.102e-228 727.0
TLS3_k127_250968_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.85e-216 681.0
TLS3_k127_250968_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000003905 229.0
TLS3_k127_250968_11 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.00000000000000000000000000000000000000000000000000000000001667 213.0
TLS3_k127_250968_12 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000002367 199.0
TLS3_k127_250968_13 Protein of unknown function (DUF2892) K03671 - - 0.0000000000000000000000000000000000002758 146.0
TLS3_k127_250968_15 Protein of unknown function (DUF2892) - - - 0.0000000000000002334 80.0
TLS3_k127_250968_16 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.000000000000000428 80.0
TLS3_k127_250968_2 PFAM peptidase M20 - - - 3.665e-214 672.0
TLS3_k127_250968_3 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 533.0
TLS3_k127_250968_4 Belongs to the ParA family K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 391.0
TLS3_k127_250968_5 Belongs to the SEDS family K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 372.0
TLS3_k127_250968_6 PFAM DegV family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 312.0
TLS3_k127_250968_7 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 303.0
TLS3_k127_250968_8 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000811 283.0
TLS3_k127_250968_9 amino acid-binding ACT domain protein K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003517 253.0
TLS3_k127_2540999_0 COGs COG4591 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 490.0
TLS3_k127_2540999_1 ATP-binding region, ATPase domain protein - - - 0.0000000000000000009263 99.0
TLS3_k127_2561786_0 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002746 280.0
TLS3_k127_2561786_1 PFAM aminotransferase class I and II K11358 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003371 284.0
TLS3_k127_2561786_2 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000001648 205.0
TLS3_k127_2561786_3 GAF domain - - - 0.000000000000000000000000000000000000000000000000006379 196.0
TLS3_k127_2583603_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 1.306e-249 785.0
TLS3_k127_2583603_1 PFAM amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000534 569.0
TLS3_k127_2583603_10 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000000000000000000009223 147.0
TLS3_k127_2583603_11 JAB/MPN domain K21140 - 3.13.1.6 0.00000000000000000001675 99.0
TLS3_k127_2583603_12 Acetyltransferase (GNAT) domain - - - 0.000000000000006675 85.0
TLS3_k127_2583603_2 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 438.0
TLS3_k127_2583603_3 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 342.0
TLS3_k127_2583603_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 337.0
TLS3_k127_2583603_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001703 263.0
TLS3_k127_2583603_6 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.000000000000000000000000000000000000000000000000000000000000000000644 232.0
TLS3_k127_2583603_7 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000003832 213.0
TLS3_k127_2588243_0 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 8.494e-230 724.0
TLS3_k127_2588243_1 heme-copper terminal oxidase activity K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 551.0
TLS3_k127_2588243_10 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 307.0
TLS3_k127_2588243_11 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 310.0
TLS3_k127_2588243_12 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 304.0
TLS3_k127_2588243_13 Binding-protein-dependent transport system inner membrane component K10234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 299.0
TLS3_k127_2588243_14 COG1175 ABC-type sugar transport systems permease components K10233 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001879 284.0
TLS3_k127_2588243_15 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000001135 254.0
TLS3_k127_2588243_16 Methyl-viologen-reducing hydrogenase, delta subunit K02572,K02573,K03522 - - 0.00000000000000000000000000000000000000000000000000000000000001722 240.0
TLS3_k127_2588243_17 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000525 217.0
TLS3_k127_2588243_18 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000007574 213.0
TLS3_k127_2588243_19 ABC transporter, substratebinding protein K10232 - - 0.000000000000000000000000000000000000000000000000000000005076 216.0
TLS3_k127_2588243_2 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 531.0
TLS3_k127_2588243_20 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000006068 104.0
TLS3_k127_2588243_3 flavoprotein, HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 446.0
TLS3_k127_2588243_4 ROK family K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 387.0
TLS3_k127_2588243_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 405.0
TLS3_k127_2588243_6 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009338 363.0
TLS3_k127_2588243_7 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 327.0
TLS3_k127_2588243_8 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 326.0
TLS3_k127_2588243_9 quinone binding K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 312.0
TLS3_k127_2606175_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0 1279.0
TLS3_k127_2606175_1 protein histidine kinase activity K02484,K07636,K07642 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 1.279e-271 872.0
TLS3_k127_2606175_10 Protein of unknown function (DUF952) K00799 - 2.5.1.18 0.0000000000000000000000000009103 117.0
TLS3_k127_2606175_11 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000008711 113.0
TLS3_k127_2606175_12 aminoglycoside hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.00001158 48.0
TLS3_k127_2606175_2 Amino acid permease - - - 1.959e-256 806.0
TLS3_k127_2606175_3 PFAM ABC transporter transmembrane region - - - 9.035e-217 688.0
TLS3_k127_2606175_4 ABC transporter, transmembrane region K06147 - - 1.011e-202 647.0
TLS3_k127_2606175_5 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 428.0
TLS3_k127_2606175_6 PFAM TrkA-N domain protein K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 286.0
TLS3_k127_2606175_7 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005306 270.0
TLS3_k127_2606175_8 TrkA-N domain K03499,K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000006442 237.0
TLS3_k127_2606175_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000001783 178.0
TLS3_k127_2613514_0 Dehydrogenase E1 component K00615 - 2.2.1.1 4.817e-315 984.0
TLS3_k127_2613514_1 e3 binding domain K00658,K09699 - 2.3.1.168,2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 376.0
TLS3_k127_2613514_2 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000001087 124.0
TLS3_k127_2613514_3 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000001232 93.0
TLS3_k127_2644670_0 domain, Protein K01219,K17624 - 3.2.1.81,3.2.1.97 8.494e-260 820.0
TLS3_k127_2644670_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 566.0
TLS3_k127_2644670_10 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002621 266.0
TLS3_k127_2644670_11 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000434 266.0
TLS3_k127_2644670_12 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000008923 246.0
TLS3_k127_2644670_13 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000001309 227.0
TLS3_k127_2644670_14 COG0437 Fe-S-cluster-containing hydrogenase components 1 K00184 - - 0.0000000000000000000000000000000000000000000000000000001616 205.0
TLS3_k127_2644670_15 2-dehydropantoate 2-reductase activity K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000213 205.0
TLS3_k127_2644670_16 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000006256 186.0
TLS3_k127_2644670_17 proteolysis K19225 - 3.4.21.105 0.000000000000000000000000000000000000000001435 166.0
TLS3_k127_2644670_18 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000002044 165.0
TLS3_k127_2644670_19 Putative regulatory protein - - - 0.0000000000000000000000000000000000000009194 151.0
TLS3_k127_2644670_2 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 533.0
TLS3_k127_2644670_20 - - - - 0.000000000000000000000000000000002645 140.0
TLS3_k127_2644670_21 Response regulator receiver - - - 0.000000000000000000000000000000004886 136.0
TLS3_k127_2644670_22 - - - - 0.00000002288 64.0
TLS3_k127_2644670_23 gas vesicle protein - - - 0.0007961 48.0
TLS3_k127_2644670_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 481.0
TLS3_k127_2644670_4 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 462.0
TLS3_k127_2644670_5 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 372.0
TLS3_k127_2644670_6 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 375.0
TLS3_k127_2644670_7 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 360.0
TLS3_k127_2644670_8 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007664 313.0
TLS3_k127_2644670_9 dipeptide transport K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001294 282.0
TLS3_k127_2647380_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 2.401e-207 665.0
TLS3_k127_2647380_1 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 307.0
TLS3_k127_2647380_2 DinB superfamily - - - 0.000000000000000000000000000000000000000005974 160.0
TLS3_k127_2647380_3 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000002938 94.0
TLS3_k127_2654047_0 response regulator, receiver K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 499.0
TLS3_k127_2654047_1 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 416.0
TLS3_k127_2654047_2 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 414.0
TLS3_k127_2654047_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 362.0
TLS3_k127_2654047_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000002288 211.0
TLS3_k127_2654047_5 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000002308 181.0
TLS3_k127_2654047_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000439 154.0
TLS3_k127_265455_0 Stage II sporulation E family protein - - - 6.211e-237 770.0
TLS3_k127_265455_1 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000257 282.0
TLS3_k127_265455_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000001008 213.0
TLS3_k127_265455_3 PFAM peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000004413 194.0
TLS3_k127_265455_4 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749 - - 0.0000000000000000000000000000000000002366 143.0
TLS3_k127_265455_6 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000001097 121.0
TLS3_k127_265455_7 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.0000000000000000000000006754 109.0
TLS3_k127_265455_8 peptidase - - - 0.0000000000000000000009672 106.0
TLS3_k127_2657404_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 3.084e-269 845.0
TLS3_k127_2657404_1 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000008422 159.0
TLS3_k127_2662376_0 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 501.0
TLS3_k127_2662376_1 pathogenesis K21471,K21687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 501.0
TLS3_k127_2662376_2 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 315.0
TLS3_k127_2662376_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000002686 194.0
TLS3_k127_2662376_4 GtrA-like protein - - - 0.00000000000000000000000000000000000000004212 159.0
TLS3_k127_2662376_5 PFAM thioesterase superfamily protein - - - 0.0000000000000000000000000000000000000002953 155.0
TLS3_k127_2662376_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000007245 147.0
TLS3_k127_2662376_7 amino acid-binding ACT domain protein K04767 - - 0.0000001686 54.0
TLS3_k127_2701464_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 6.285e-298 925.0
TLS3_k127_2701464_1 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 427.0
TLS3_k127_2701464_10 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000236 150.0
TLS3_k127_2701464_11 PFAM peptidase M14, carboxypeptidase A - - - 0.000000000000000000000000000006066 133.0
TLS3_k127_2701464_12 Baseplate J-like protein K01218 - 3.2.1.78 0.00001386 53.0
TLS3_k127_2701464_2 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 411.0
TLS3_k127_2701464_3 PFAM molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000892 366.0
TLS3_k127_2701464_4 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 350.0
TLS3_k127_2701464_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 325.0
TLS3_k127_2701464_6 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 314.0
TLS3_k127_2701464_7 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 317.0
TLS3_k127_2701464_8 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 312.0
TLS3_k127_2701464_9 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003206 248.0
TLS3_k127_2744994_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 7.583e-245 765.0
TLS3_k127_2744994_1 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 509.0
TLS3_k127_2744994_2 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 480.0
TLS3_k127_2744994_3 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000006065 182.0
TLS3_k127_2744994_4 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000002538 115.0
TLS3_k127_2744994_5 cytochrome c biogenesis protein, transmembrane region K06196 - - 0.00002975 49.0
TLS3_k127_2829177_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 400.0
TLS3_k127_2829177_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008292 324.0
TLS3_k127_2829177_2 Glyoxalase-like domain K07032 - - 0.0000000000000000000000000000000000000000000000000005499 186.0
TLS3_k127_2829177_3 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.0000000000000008836 79.0
TLS3_k127_2832039_0 Domain of unknown function (DUF4040) K05559,K05565 - - 1.352e-253 813.0
TLS3_k127_2832039_1 Pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 1.405e-223 701.0
TLS3_k127_2832039_10 Pfam:DUF385 - - - 0.000000000000000000000000006602 113.0
TLS3_k127_2832039_11 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000001413 113.0
TLS3_k127_2832039_12 monovalent cation:proton antiporter activity K05571 - - 0.0000000000000000000005335 99.0
TLS3_k127_2832039_13 Protein of unknown function (DUF3592) - - - 0.00000000000004402 78.0
TLS3_k127_2832039_2 Proton-conducting membrane transporter K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 518.0
TLS3_k127_2832039_3 translation release factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009629 475.0
TLS3_k127_2832039_4 pyridine nucleotide-disulfide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006686 456.0
TLS3_k127_2832039_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 394.0
TLS3_k127_2832039_6 PFAM sodium calcium exchanger membrane region K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 398.0
TLS3_k127_2832039_7 PFAM Bile acid sodium symporter K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 331.0
TLS3_k127_2832039_8 multisubunit Na H antiporter MnhE subunit K05569 - - 0.000000000000000000000000000000003833 134.0
TLS3_k127_2832039_9 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05560,K05567 - - 0.00000000000000000000000000009296 119.0
TLS3_k127_2914275_0 Immune inhibitor A peptidase M6 - - - 3.33e-238 754.0
TLS3_k127_2914275_1 ATPase associated with various cellular activities, AAA_5 K03696 - - 3.285e-226 708.0
TLS3_k127_2914275_2 PFAM metal-dependent phosphohydrolase, HD sub domain K02030,K02103,K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000004009 254.0
TLS3_k127_2914275_3 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000006902 211.0
TLS3_k127_2931156_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.0 1233.0
TLS3_k127_2931156_1 fad binding domain-containing protein - - - 0.0000000000000000000000000000000000001371 154.0
TLS3_k127_2946207_0 Aminotransferase class-V K01556 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 460.0
TLS3_k127_2946207_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 315.0
TLS3_k127_2946207_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000037 130.0
TLS3_k127_2957334_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 4.77e-275 854.0
TLS3_k127_2957334_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 2.117e-202 644.0
TLS3_k127_2957334_2 TAP-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 377.0
TLS3_k127_2957334_3 ABC transporter K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009456 347.0
TLS3_k127_2957334_4 sodium ABC transporter, permease K09696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 306.0
TLS3_k127_2957334_5 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000001301 196.0
TLS3_k127_2957334_6 - - - - 0.0000000000000000000000000000000000000000008816 159.0
TLS3_k127_2965115_0 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 572.0
TLS3_k127_2965115_1 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 422.0
TLS3_k127_2965115_2 phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007095 309.0
TLS3_k127_2965115_3 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00571,K00847,K00852 - 2.1.1.72,2.7.1.15,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 293.0
TLS3_k127_2965115_4 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000003005 163.0
TLS3_k127_2965793_0 Rieske [2Fe-2S] domain - - - 1.61e-210 657.0
TLS3_k127_2965793_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 486.0
TLS3_k127_2965793_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008651 333.0
TLS3_k127_2965793_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000002472 109.0
TLS3_k127_2983112_0 Oligopeptidase F K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 610.0
TLS3_k127_2983112_1 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 334.0
TLS3_k127_2983112_10 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000001456 181.0
TLS3_k127_2983112_11 histidine kinase A domain protein - - - 0.00000000000000000000000000000000001503 158.0
TLS3_k127_2983112_12 DNA-binding transcription factor activity K03892 - - 0.00000000000000000000000000006383 118.0
TLS3_k127_2983112_13 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.0000000000000000000000000711 111.0
TLS3_k127_2983112_14 STAS domain K04749,K06378 - - 0.000000000000000008936 87.0
TLS3_k127_2983112_15 Histidine kinase-like ATPase domain - - - 0.00000000000007726 86.0
TLS3_k127_2983112_2 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 321.0
TLS3_k127_2983112_3 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000001881 255.0
TLS3_k127_2983112_4 PFAM Sporulation stage II, protein E C-terminal K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000009683 275.0
TLS3_k127_2983112_5 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000001237 243.0
TLS3_k127_2983112_6 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000006465 215.0
TLS3_k127_2983112_7 - - - - 0.000000000000000000000000000000000000000000000000000002296 201.0
TLS3_k127_2983112_8 DegV family - - - 0.00000000000000000000000000000000000000000000000000006072 197.0
TLS3_k127_2983112_9 GNAT acetyltransferase - - - 0.00000000000000000000000000000000000000000000000001584 188.0
TLS3_k127_2999167_0 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 359.0
TLS3_k127_2999167_1 TIGRFAM metal dependent phophohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 287.0
TLS3_k127_2999167_2 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005134 257.0
TLS3_k127_2999167_3 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001018 262.0
TLS3_k127_2999167_4 Protein of unknown function (DUF4230) - - - 0.0000000000000000000000000000006257 131.0
TLS3_k127_2999167_5 - - - - 0.000000000000000000000000004576 127.0
TLS3_k127_2999167_6 Chagasin family peptidase inhibitor I42 K14475 - - 0.000000000000000007164 89.0
TLS3_k127_2999167_7 ABC-type phosphate phosphonate transport system periplasmic component K02044 - - 0.00000000000000038 92.0
TLS3_k127_2999167_8 - - - - 0.000000000000001547 89.0
TLS3_k127_2999167_9 NlpC/P60 family K01227,K01447,K01448,K01876,K06385,K07260,K11060,K11062,K21471,K21472 - 3.2.1.96,3.4.17.14,3.5.1.28,6.1.1.12 0.000004905 57.0
TLS3_k127_300806_0 FAD linked oxidases, C-terminal domain K18930 - - 1.429e-299 945.0
TLS3_k127_300806_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004626 506.0
TLS3_k127_300806_10 SPTR B7KVZ8 Transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000001734 115.0
TLS3_k127_300806_11 GYD domain - - - 0.0000000000000000000000000965 109.0
TLS3_k127_300806_2 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 391.0
TLS3_k127_300806_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02484,K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 331.0
TLS3_k127_300806_4 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 290.0
TLS3_k127_300806_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 287.0
TLS3_k127_300806_6 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000001955 241.0
TLS3_k127_300806_7 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000002731 239.0
TLS3_k127_300806_8 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.000000000000000000000000000000000000000000000000000000002366 207.0
TLS3_k127_300806_9 PFAM transcriptional regulator PadR family protein - - - 0.0000000000000000000000000001804 121.0
TLS3_k127_3076402_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 8.901e-320 998.0
TLS3_k127_3076402_1 Lysine-2,3-aminomutase K01843 - 5.4.3.2 1.737e-245 762.0
TLS3_k127_3076402_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009131 337.0
TLS3_k127_3076402_3 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000001171 221.0
TLS3_k127_3076402_4 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000001048 117.0
TLS3_k127_31013_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 9.985e-312 978.0
TLS3_k127_31013_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.096e-274 868.0
TLS3_k127_31013_10 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001477 280.0
TLS3_k127_31013_11 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007556 277.0
TLS3_k127_31013_12 YibE/F-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001556 257.0
TLS3_k127_31013_13 PFAM major facilitator superfamily MFS_1 K08223 - - 0.00000000000000000000000000000000000000000000000000000000009044 218.0
TLS3_k127_31013_14 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000000000002137 206.0
TLS3_k127_31013_15 homoserine transmembrane transporter activity K06600,K06895 - - 0.000000000000000000000000000000000000000000000000000000004085 205.0
TLS3_k127_31013_16 Gaf domain K03406 - - 0.0000000000000000000000000000000000000000000000000000155 199.0
TLS3_k127_31013_17 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000001561 193.0
TLS3_k127_31013_18 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.00000000000000000000000000000000000000000000002336 186.0
TLS3_k127_31013_19 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000002016 158.0
TLS3_k127_31013_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 564.0
TLS3_k127_31013_20 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000009753 139.0
TLS3_k127_31013_21 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000006015 100.0
TLS3_k127_31013_22 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000001556 98.0
TLS3_k127_31013_23 Alpha/beta hydrolase family - - - 0.000000000000000006384 89.0
TLS3_k127_31013_24 - - - - 0.00000000000000007795 81.0
TLS3_k127_31013_26 membrane - - - 0.000000003065 68.0
TLS3_k127_31013_28 - - - - 0.0001442 49.0
TLS3_k127_31013_3 Belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 496.0
TLS3_k127_31013_4 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 455.0
TLS3_k127_31013_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 408.0
TLS3_k127_31013_6 NUBPL iron-transfer P-loop NTPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 368.0
TLS3_k127_31013_7 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 373.0
TLS3_k127_31013_8 PFAM CobQ CobB MinD ParA nucleotide binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 304.0
TLS3_k127_31013_9 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 300.0
TLS3_k127_3126610_0 Putative carbohydrate binding domain K00702 - 2.4.1.20 0.0 1247.0
TLS3_k127_3126610_1 PFAM glycoside hydrolase, family 3 domain protein K05349 - 3.2.1.21 3.769e-268 845.0
TLS3_k127_3126610_10 ABC transporter transmembrane region - - - 0.000000000000000000000000000000000000006391 151.0
TLS3_k127_3126610_11 Polysaccharide deacetylase - - - 0.000000000000000000000000000000005493 134.0
TLS3_k127_3126610_12 (ABC) transporter K06147 - - 0.000000000000000000000000000003086 123.0
TLS3_k127_3126610_2 PFAM carbohydrate kinase K00854 - 2.7.1.17 3.358e-238 744.0
TLS3_k127_3126610_3 PFAM Xylose isomerase domain protein TIM barrel K01805 - 5.3.1.5 7.753e-213 664.0
TLS3_k127_3126610_4 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008155 579.0
TLS3_k127_3126610_5 solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 518.0
TLS3_k127_3126610_6 PFAM Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 383.0
TLS3_k127_3126610_7 PFAM Binding-protein-dependent transport system inner membrane component K02026,K10242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 344.0
TLS3_k127_3126610_8 periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 323.0
TLS3_k127_3126610_9 Domain of unknown function (DUF4380) - - - 0.00000000000000000000000000000000000000000000000000000000000000009001 231.0
TLS3_k127_3224206_0 Peptidase dimerisation domain protein K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 312.0
TLS3_k127_3224206_1 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004274 267.0
TLS3_k127_3224206_2 ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000225 263.0
TLS3_k127_3224206_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000401 124.0
TLS3_k127_3224206_4 phosphate ion binding K02040 - - 0.0000001969 61.0
TLS3_k127_3225577_0 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 6.1e-202 641.0
TLS3_k127_3225577_1 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 395.0
TLS3_k127_326017_0 Serine carboxypeptidase - - - 1.811e-197 628.0
TLS3_k127_326017_1 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820,K15916 - 2.6.1.16,5.3.1.8,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 407.0
TLS3_k127_326017_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 314.0
TLS3_k127_326017_3 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000007749 173.0
TLS3_k127_326017_4 FeoA K03709 - - 0.000000000000000000000000000000000000000001527 164.0
TLS3_k127_326017_5 extracellular solute-binding protein, family 1 K02012 - - 0.0000000000000000000000000000009708 125.0
TLS3_k127_3262957_0 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 459.0
TLS3_k127_3262957_1 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 336.0
TLS3_k127_3262957_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001659 292.0
TLS3_k127_3262957_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004094 273.0
TLS3_k127_3262957_4 SpoU rRNA Methylase family K03218,K03437,K21514 - 2.1.1.185,2.1.1.208 0.0000000000000000000000000000000000000000000000000000000000000000000001129 246.0
TLS3_k127_3262957_5 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000002274 86.0
TLS3_k127_3339028_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.745e-266 830.0
TLS3_k127_3339028_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 470.0
TLS3_k127_3339028_2 Dystroglycan-type cadherin-like domains. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007574 374.0
TLS3_k127_3339028_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000003033 242.0
TLS3_k127_3339028_4 PFAM Roadblock LC7 family protein K07131 - - 0.0000000000000000000000000000000000000000000000006521 179.0
TLS3_k127_3339028_5 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000001115 176.0
TLS3_k127_3339028_6 Belongs to the peptidase S8 family - - - 0.0000000000000000000000001794 122.0
TLS3_k127_3339028_7 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000002545 90.0
TLS3_k127_3350624_0 dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 459.0
TLS3_k127_3350624_3 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000002097 105.0
TLS3_k127_3381090_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 9.42e-218 682.0
TLS3_k127_3381090_1 PFAM PfkB domain protein K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 431.0
TLS3_k127_3381090_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 391.0
TLS3_k127_3393883_0 PFAM alpha amylase, catalytic K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 544.0
TLS3_k127_3393883_1 SMART alpha amylase, catalytic sub domain K01176 - 3.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 471.0
TLS3_k127_344978_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1142.0
TLS3_k127_344978_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 559.0
TLS3_k127_344978_10 domain in sensory proteins (DUF2308) - - - 0.000000000000000000000000000000000000000000000000003881 187.0
TLS3_k127_344978_11 Putative zincin peptidase - - - 0.00000000000000000000000000000000000000000000001919 177.0
TLS3_k127_344978_12 TIGRFAM degV family protein - - - 0.0000000000000000000000000000000000000000000000291 180.0
TLS3_k127_344978_13 TIGRFAM lycopene cyclase domain K22502 - 5.5.1.19 0.000000000000000000000000000000000000001148 157.0
TLS3_k127_344978_14 Protein of unknown function (DUF1475) - - - 0.0000000000000000000000000000001645 132.0
TLS3_k127_344978_15 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000001973 80.0
TLS3_k127_344978_2 PFAM Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 506.0
TLS3_k127_344978_3 DNA photolyase domain protein K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 479.0
TLS3_k127_344978_4 Protein of unknown function (DUF1295) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 414.0
TLS3_k127_344978_5 PFAM Cytochrome P450 - GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016125,GO:0016491,GO:0030312,GO:0044238,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901615 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 419.0
TLS3_k127_344978_6 PFAM regulatory protein, MerR K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 371.0
TLS3_k127_344978_7 Alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 365.0
TLS3_k127_344978_8 drug transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 363.0
TLS3_k127_344978_9 Protein of unknown function (DUF3159) - - - 0.00000000000000000000000000000000000000000000000000003269 196.0
TLS3_k127_3460611_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 554.0
TLS3_k127_3460611_1 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 433.0
TLS3_k127_3460611_10 metal-dependent membrane protease K07052 - - 0.000000000000000000001572 104.0
TLS3_k127_3460611_11 Acetyltransferase (GNAT) domain K03826 - - 0.000000000000000000002119 99.0
TLS3_k127_3460611_12 Protein of unknown function (DUF1761) - - - 0.0000000000001464 77.0
TLS3_k127_3460611_13 cyclic 2,3-diphosphoglycerate synthetase activity K05716 - - 0.000000000003941 66.0
TLS3_k127_3460611_14 - - - - 0.00000000002012 70.0
TLS3_k127_3460611_2 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 418.0
TLS3_k127_3460611_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 413.0
TLS3_k127_3460611_4 GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 304.0
TLS3_k127_3460611_5 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05827,K05844 - 6.3.2.43 0.0000000000000000000000000000000000000000000000000000001616 205.0
TLS3_k127_3460611_6 FtsZ-dependent cytokinesis - - - 0.00000000000000000000000000000000000000000000000006319 184.0
TLS3_k127_3460611_7 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000005619 168.0
TLS3_k127_3460611_8 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000006927 160.0
TLS3_k127_3460611_9 PFAM ABC transporter related K06158 - - 0.00000000000000000000000000000000000226 141.0
TLS3_k127_346365_0 PFAM Dak phosphatase K07030 - - 3.072e-205 654.0
TLS3_k127_346365_1 SMART serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008379 340.0
TLS3_k127_346365_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000001388 231.0
TLS3_k127_346365_3 PFAM Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000544 154.0
TLS3_k127_346365_4 Asp23 family, cell envelope-related function - - - 0.000000000000000000000000000000012 130.0
TLS3_k127_346365_5 alcohol dehydrogenase - - - 0.00000000000000000000000000000001427 139.0
TLS3_k127_346365_6 negative regulation of transcription, DNA-templated K10947 - - 0.00000000000000000000000000000004846 127.0
TLS3_k127_346365_7 ribosomal protein L28 K02902 - - 0.000000000000000001901 86.0
TLS3_k127_346365_8 - - - - 0.0000000001046 73.0
TLS3_k127_3464626_0 transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 459.0
TLS3_k127_3464626_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 382.0
TLS3_k127_3464626_10 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000005448 137.0
TLS3_k127_3464626_11 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000000002374 101.0
TLS3_k127_3464626_12 TIGRFAM Competence protein ComEA, helix-hairpin-helix K17717 - 3.1.4.4 0.000000000000000000009358 99.0
TLS3_k127_3464626_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K01919,K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 359.0
TLS3_k127_3464626_3 PFAM TrkA-N domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 319.0
TLS3_k127_3464626_4 PFAM Stage II sporulation E family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001563 283.0
TLS3_k127_3464626_5 SPTR Cell surface protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001363 284.0
TLS3_k127_3464626_6 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000001055 271.0
TLS3_k127_3464626_7 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000000001293 223.0
TLS3_k127_3464626_8 TIGRFAM polymorphic outer membrane protein K21449 - - 0.0000000000000000000000000000000000000000000002691 185.0
TLS3_k127_3464626_9 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - 0.000000000000000000000000000000006358 131.0
TLS3_k127_3470600_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 8.595e-210 660.0
TLS3_k127_3470600_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000003345 190.0
TLS3_k127_3470600_2 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.0000000000000000000000000000000000007985 146.0
TLS3_k127_3470600_3 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000000000000006535 129.0
TLS3_k127_3470600_5 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000001093 91.0
TLS3_k127_3470600_7 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain' K04771 GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 0.000003382 59.0
TLS3_k127_3485812_0 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000006119 228.0
TLS3_k127_3485812_1 Acetyltransferase (GNAT) domain K03824 - - 0.0000000000000000000000000000000001796 139.0
TLS3_k127_3485812_2 Creatininase K01470 - 3.5.2.10 0.000000008654 65.0
TLS3_k127_3523438_0 trisaccharide binding K03556 - - 6.563e-239 752.0
TLS3_k127_3523438_1 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000003658 159.0
TLS3_k127_3539286_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1412.0
TLS3_k127_3539286_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.53e-198 625.0
TLS3_k127_3539286_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 476.0
TLS3_k127_3539286_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 397.0
TLS3_k127_3539286_4 PFAM RNA binding S1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000006234 206.0
TLS3_k127_3539286_5 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000000000000000000005418 183.0
TLS3_k127_3539286_6 aspartic-type endopeptidase activity K02236,K02506,K02654 - 3.4.23.43 0.0000000000000000000000000000007431 131.0
TLS3_k127_3545766_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 1.515e-240 760.0
TLS3_k127_3545766_1 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 464.0
TLS3_k127_3545766_2 MFS_1 like family K08151,K08153 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002997 254.0
TLS3_k127_3545766_3 FCD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001584 239.0
TLS3_k127_3545766_4 Acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000004243 207.0
TLS3_k127_3545766_5 chain release factor K15034 - - 0.00000000000000000000000000000000000335 141.0
TLS3_k127_3545766_6 SEFIR domain - - - 0.00000000000000000000009411 98.0
TLS3_k127_3545766_7 COG3666 Transposase and inactivated derivatives - - - 0.000002578 49.0
TLS3_k127_3575711_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1205.0
TLS3_k127_3575711_1 FAD linked oxidases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 553.0
TLS3_k127_3575711_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 369.0
TLS3_k127_3575711_3 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002808 291.0
TLS3_k127_3581954_0 PFAM NADH flavin oxidoreductase NADH oxidase K00317 - 1.5.8.1,1.5.8.2 5.748e-320 991.0
TLS3_k127_3581954_1 PFAM ABC transporter transmembrane region K06147 - - 3.883e-241 761.0
TLS3_k127_3581954_10 FES K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 305.0
TLS3_k127_3581954_11 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001619 284.0
TLS3_k127_3581954_12 L-asparaginase II K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002146 280.0
TLS3_k127_3581954_13 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000008986 225.0
TLS3_k127_3581954_14 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000001019 201.0
TLS3_k127_3581954_15 methyltransferase - - - 0.0000000000000000000000000000000000000000000000009472 184.0
TLS3_k127_3581954_16 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000000000000002612 171.0
TLS3_k127_3581954_17 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000001783 176.0
TLS3_k127_3581954_18 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K09007,K13940,K17488 - 2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25 0.000000000000000000000000000000000000000000001875 171.0
TLS3_k127_3581954_19 Protein of unknown function (DUF2568) - - - 0.000000000000000000000000000000000001003 142.0
TLS3_k127_3581954_2 PFAM ABC transporter transmembrane region K06147 - - 2.729e-238 755.0
TLS3_k127_3581954_20 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.000000000000000000000000000000003843 136.0
TLS3_k127_3581954_21 Uncharacterized conserved protein (DUF2196) - - - 0.0000000000000000000000001124 107.0
TLS3_k127_3581954_22 TIR domain K12132 - 2.7.11.1 0.00000000000000003375 91.0
TLS3_k127_3581954_23 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000009155 68.0
TLS3_k127_3581954_3 COG0520 Selenocysteine lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 541.0
TLS3_k127_3581954_4 fad dependent oxidoreductase K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 488.0
TLS3_k127_3581954_5 PhoQ Sensor K07682 GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 399.0
TLS3_k127_3581954_6 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 368.0
TLS3_k127_3581954_7 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 342.0
TLS3_k127_3581954_8 periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 324.0
TLS3_k127_3581954_9 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 312.0
TLS3_k127_3629394_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 4.035e-218 686.0
TLS3_k127_3629394_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.068e-200 631.0
TLS3_k127_3629394_2 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 483.0
TLS3_k127_3629394_3 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000003178 234.0
TLS3_k127_3629394_4 cytokinin biosynthetic process K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000003996 181.0
TLS3_k127_3629394_5 - K07020,K18614 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009111,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0034641,GO:0042365,GO:0042737,GO:0042802,GO:0042803,GO:0042816,GO:0042820,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046483,GO:0046700,GO:0046983,GO:0047411,GO:0071704,GO:0072524,GO:0072526,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.1.29 0.0000000000000000000000000000000000007327 156.0
TLS3_k127_3629394_6 MazG-like family - - - 0.00000000000000000000000000000001711 128.0
TLS3_k127_3632194_0 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 440.0
TLS3_k127_3632194_1 alginic acid biosynthetic process K12287 - - 0.00000000000000000000000000000000000000001396 177.0
TLS3_k127_3632194_2 alginic acid biosynthetic process K12287 - - 0.000000000000000000000000000000000000003985 168.0
TLS3_k127_3675001_0 Extracellular solute-binding protein K02055,K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 557.0
TLS3_k127_3675001_1 ATPase activity K02052,K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 457.0
TLS3_k127_3675001_2 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 445.0
TLS3_k127_3675001_3 PFAM binding-protein-dependent transport systems inner membrane component K02054,K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 391.0
TLS3_k127_3675001_4 ABC transporter (permease) K02053 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 362.0
TLS3_k127_3675001_5 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 296.0
TLS3_k127_3675001_6 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.00000000000000000000000000000000000000000000000000000000001221 211.0
TLS3_k127_3675001_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000004725 72.0
TLS3_k127_3675001_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000146 70.0
TLS3_k127_3700862_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1535.0
TLS3_k127_3700862_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007739 242.0
TLS3_k127_3703703_0 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 1.252e-239 751.0
TLS3_k127_3703703_1 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 480.0
TLS3_k127_3703703_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 370.0
TLS3_k127_3703703_3 TIGRFAM Competence protein ComEA, helix-hairpin-helix K17717 - 3.1.4.4 0.0000000000000000000000000000000000000000000000000000000000004819 216.0
TLS3_k127_3863616_0 Molydopterin dinucleotide binding domain - - - 9.177e-229 731.0
TLS3_k127_3863616_1 PFAM Polysulphide reductase, NrfD K00185 - - 3.374e-201 636.0
TLS3_k127_3863616_2 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 352.0
TLS3_k127_3863616_3 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000001277 212.0
TLS3_k127_3863616_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000009051 171.0
TLS3_k127_3863616_5 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000003665 137.0
TLS3_k127_3863616_6 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000332 130.0
TLS3_k127_3863616_7 Helix-turn-helix domain - - - 0.000123 48.0
TLS3_k127_386917_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 519.0
TLS3_k127_386917_1 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 471.0
TLS3_k127_386917_2 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 329.0
TLS3_k127_386917_3 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000003823 182.0
TLS3_k127_3890261_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 573.0
TLS3_k127_3890261_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 468.0
TLS3_k127_3890261_2 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 435.0
TLS3_k127_3890261_3 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 355.0
TLS3_k127_3890261_4 DNA-binding transcription factor activity K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000004872 183.0
TLS3_k127_3890261_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000001435 138.0
TLS3_k127_3890261_6 ATPases associated with a variety of cellular activities K09691 - - 0.0000000000007527 71.0
TLS3_k127_3890261_7 methyltransferase K16215 - 2.1.1.243 0.000000000005593 74.0
TLS3_k127_3927244_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 536.0
TLS3_k127_3927244_1 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.0000000000000000000000000000000000000000002043 169.0
TLS3_k127_3927244_2 PFAM AMP-dependent synthetase and ligase K18661 - - 0.0000000000000000000000000000000003563 132.0
TLS3_k127_3927244_3 VanZ like family - - - 0.00000000004012 66.0
TLS3_k127_3927244_4 - - - - 0.0001873 50.0
TLS3_k127_397877_0 Aspartate ammonia-lyase K01744 - 4.3.1.1 1.717e-212 669.0
TLS3_k127_397877_1 PFAM VWA containing CoxE family protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 540.0
TLS3_k127_397877_10 - - - - 0.00000000000000002915 85.0
TLS3_k127_397877_12 - - - - 0.000005504 54.0
TLS3_k127_397877_2 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 474.0
TLS3_k127_397877_3 PFAM Radical SAM domain protein K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 381.0
TLS3_k127_397877_4 transferase activity, transferring glycosyl groups K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 310.0
TLS3_k127_397877_5 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 289.0
TLS3_k127_397877_6 Domain of unknown function (DUF1905) - - - 0.0000000000000000000000000000000000002388 142.0
TLS3_k127_397877_7 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000001317 104.0
TLS3_k127_397877_8 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K10697 - - 0.0000000000000000000001725 102.0
TLS3_k127_397877_9 phosphorelay signal transduction system - - - 0.00000000000000000006758 93.0
TLS3_k127_4113517_0 AAA ATPase domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 577.0
TLS3_k127_4113517_1 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 418.0
TLS3_k127_4113517_2 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 336.0
TLS3_k127_4113517_3 Domain of unknown function (DUF4129) - - - 0.0000000000000000000002904 110.0
TLS3_k127_4113517_5 Belongs to the 'phage' integrase family - - - 0.00000009578 55.0
TLS3_k127_4125125_0 Beta-Casp domain K07576 - - 2.499e-200 633.0
TLS3_k127_4125125_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 488.0
TLS3_k127_4125125_10 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 325.0
TLS3_k127_4125125_11 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 312.0
TLS3_k127_4125125_12 Transmembrane secretion effector K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002555 288.0
TLS3_k127_4125125_13 - K07403 - - 0.0000000000000000000000000000000000000000000000004534 181.0
TLS3_k127_4125125_14 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000001718 147.0
TLS3_k127_4125125_15 2 iron, 2 sulfur cluster binding K02823,K05368 - 1.16.1.3,1.5.1.41 0.00000000000000000000000000000009496 136.0
TLS3_k127_4125125_16 acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000006243 126.0
TLS3_k127_4125125_18 Protein kinase domain K12132 - 2.7.11.1 0.000000004079 70.0
TLS3_k127_4125125_19 Ig-like domain from next to BRCA1 gene - - - 0.00000007591 57.0
TLS3_k127_4125125_2 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 443.0
TLS3_k127_4125125_3 PFAM CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 445.0
TLS3_k127_4125125_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 430.0
TLS3_k127_4125125_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 427.0
TLS3_k127_4125125_6 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 416.0
TLS3_k127_4125125_7 NAD synthase K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 411.0
TLS3_k127_4125125_8 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 372.0
TLS3_k127_4125125_9 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 349.0
TLS3_k127_4136201_0 PFAM glycosyl transferase family 3 K00756 - 2.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 589.0
TLS3_k127_4136201_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K00773,K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29,2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 424.0
TLS3_k127_4136201_10 Protein of unknown function (DUF2905) - - - 0.000000000000001808 78.0
TLS3_k127_4136201_11 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000005344 71.0
TLS3_k127_4136201_12 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000002665 64.0
TLS3_k127_4136201_13 peroxiredoxin activity K03564 - 1.11.1.15 0.0003547 46.0
TLS3_k127_4136201_2 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 423.0
TLS3_k127_4136201_3 Belongs to the peptidase S51 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 326.0
TLS3_k127_4136201_4 Alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001866 287.0
TLS3_k127_4136201_5 uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001681 274.0
TLS3_k127_4136201_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000003259 229.0
TLS3_k127_4136201_7 - - - - 0.000000000000000000000000000000000000000000000000000000000002406 219.0
TLS3_k127_4136201_8 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000001598 200.0
TLS3_k127_4136201_9 AhpC/TSA family K03564 - 1.11.1.15 0.0000000000000000000000000002969 117.0
TLS3_k127_4190202_0 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile K01241 - 3.2.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 417.0
TLS3_k127_4190202_1 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 406.0
TLS3_k127_4190202_10 serine threonine protein kinase K03587,K08884,K12132 - 2.7.11.1,3.4.16.4 0.0000000000007075 81.0
TLS3_k127_4190202_11 serine-type aminopeptidase activity K14475 - - 0.00000000004516 73.0
TLS3_k127_4190202_12 Protein conserved in bacteria K00548,K03469,K11942 - 2.1.1.13,3.1.26.4,5.4.99.13 0.000025 48.0
TLS3_k127_4190202_13 Mut7-C RNAse domain - - - 0.0004021 47.0
TLS3_k127_4190202_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 371.0
TLS3_k127_4190202_3 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000001125 137.0
TLS3_k127_4190202_5 Nucleotidyltransferase domain K07075 - - 0.00000000000000000000000006087 113.0
TLS3_k127_4190202_6 Protein of unknown function (DUF2283) - - - 0.000000000000000000000004356 102.0
TLS3_k127_4190202_7 Metalloenzyme superfamily - - - 0.00000000000000000003385 94.0
TLS3_k127_4190202_8 Protein of unknown function (DUF433) - - - 0.00000000000000000003723 91.0
TLS3_k127_4190202_9 Mut7-C RNAse domain - - - 0.0000000000000001753 83.0
TLS3_k127_4262218_0 - - - - 0.0000000000000000000000000000000000000005399 169.0
TLS3_k127_4262218_1 OsmC-like protein K07397 - - 0.000000000000000000000000000000000001244 142.0
TLS3_k127_4262218_2 YhhN family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000009852 112.0
TLS3_k127_4262218_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000004448 97.0
TLS3_k127_4262218_4 - - - - 0.00000006117 57.0
TLS3_k127_4298315_0 PFAM ABC transporter related K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 388.0
TLS3_k127_4298315_1 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000000000000004687 130.0
TLS3_k127_4298315_2 Ig-like domain from next to BRCA1 gene - - - 0.0000000000000000000000000001909 126.0
TLS3_k127_431377_0 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 554.0
TLS3_k127_431377_1 short-chain dehydrogenase reductase SDR K12454 - 5.1.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 450.0
TLS3_k127_431377_2 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 443.0
TLS3_k127_431377_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000221 263.0
TLS3_k127_431377_4 PFAM Rhomboid family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001881 258.0
TLS3_k127_431377_5 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000004444 218.0
TLS3_k127_431377_6 Mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000001618 163.0
TLS3_k127_431377_7 lysyltransferase activity K07027 - - 0.000000000000000000000000000003444 132.0
TLS3_k127_431377_8 Methyltransferase domain - - - 0.000000000000000000002767 103.0
TLS3_k127_4316322_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000001871 200.0
TLS3_k127_4324486_0 elongation factor Tu domain 2 protein K02355 - - 4.215e-299 931.0
TLS3_k127_4324486_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 428.0
TLS3_k127_4324486_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003265 270.0
TLS3_k127_4324486_3 methyltransferase activity K00569 - 2.1.1.67 0.000000000000000000000000000000000001564 145.0
TLS3_k127_4324486_4 PBS lyase HEAT-like repeat - - - 0.000000000000000000001062 108.0
TLS3_k127_4324486_5 Thioredoxin - - - 0.0002323 46.0
TLS3_k127_4324486_6 - - - - 0.0004845 45.0
TLS3_k127_437954_0 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 458.0
TLS3_k127_437954_1 Belongs to the catalase family K03781 - 1.11.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 398.0
TLS3_k127_437954_2 COG0840 Methyl-accepting chemotaxis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 292.0
TLS3_k127_437954_3 PRC-barrel domain - - - 0.00000000000000000000000000000000000000000000000000000000003258 207.0
TLS3_k127_437954_4 Putative transposase - - - 0.0000000000002213 73.0
TLS3_k127_437954_5 Putative transposase - - - 0.00001336 48.0
TLS3_k127_438087_0 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 335.0
TLS3_k127_438087_1 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006186 272.0
TLS3_k127_438087_2 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000003339 194.0
TLS3_k127_4408611_0 Heat shock 70 kDa protein K04043 - - 4.78e-300 930.0
TLS3_k127_4408611_1 PFAM major facilitator superfamily MFS_1 - - - 5.772e-198 626.0
TLS3_k127_4408611_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002874 259.0
TLS3_k127_4408611_11 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001509 279.0
TLS3_k127_4408611_12 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000011 244.0
TLS3_k127_4408611_13 lipid binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000001613 245.0
TLS3_k127_4408611_14 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001938 235.0
TLS3_k127_4408611_15 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000002772 230.0
TLS3_k127_4408611_16 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000002469 202.0
TLS3_k127_4408611_17 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000008596 213.0
TLS3_k127_4408611_18 RibD C-terminal domain K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000002532 189.0
TLS3_k127_4408611_19 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000002068 142.0
TLS3_k127_4408611_2 Glycosyltransferase family 28 N-terminal domain K05841 - 2.4.1.173 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 554.0
TLS3_k127_4408611_20 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000003793 135.0
TLS3_k127_4408611_21 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000003845 130.0
TLS3_k127_4408611_22 PFAM membrane protein of K08972 - - 0.000000000000000000000000000001641 124.0
TLS3_k127_4408611_24 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.0000000000000000000005596 103.0
TLS3_k127_4408611_25 glucan 1,4-alpha-glucosidase activity - - - 0.00000003144 67.0
TLS3_k127_4408611_3 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009103 435.0
TLS3_k127_4408611_4 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 390.0
TLS3_k127_4408611_5 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 347.0
TLS3_k127_4408611_6 AAA domain K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 327.0
TLS3_k127_4408611_7 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 314.0
TLS3_k127_4408611_8 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 308.0
TLS3_k127_4408611_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003943 297.0
TLS3_k127_4427887_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.22e-216 677.0
TLS3_k127_4427887_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003665 270.0
TLS3_k127_4427887_2 TIGRFAM MoaD family protein K03636 - - 0.000000000000000000000000001443 115.0
TLS3_k127_4460364_0 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000124 264.0
TLS3_k127_4460364_1 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000000000000000000000000000000000001924 222.0
TLS3_k127_4460364_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000004834 142.0
TLS3_k127_4473904_0 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000005652 239.0
TLS3_k127_4473904_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000003282 235.0
TLS3_k127_4473904_2 - - - - 0.00000000000000000000000000000000000006691 150.0
TLS3_k127_4473904_3 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000001854 130.0
TLS3_k127_4620204_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 615.0
TLS3_k127_4620204_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000001355 176.0
TLS3_k127_4638719_0 Peptidase dimerisation domain protein K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 416.0
TLS3_k127_4638719_1 PFAM PSP1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 342.0
TLS3_k127_4638719_2 Response regulator, receiver K02487,K03407,K03413,K06596,K11526,K13490 GO:0003674,GO:0005488,GO:0005515,GO:0019904 2.7.13.3 0.00000000000000000000000000000000000000000000000000002044 194.0
TLS3_k127_4638719_3 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000004062 190.0
TLS3_k127_4638719_4 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000000000000000000000000003929 166.0
TLS3_k127_4638719_5 Ami_3 K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.0000000001695 72.0
TLS3_k127_4638719_6 amino acid-binding ACT domain protein K04767 - - 0.0000001686 54.0
TLS3_k127_4677989_0 histidine kinase A domain protein - - - 0.0 1817.0
TLS3_k127_4677989_1 ATP synthesis coupled electron transport K00336 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944 1.6.5.3 1.923e-303 952.0
TLS3_k127_4677989_10 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 518.0
TLS3_k127_4677989_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 502.0
TLS3_k127_4677989_12 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008379 443.0
TLS3_k127_4677989_13 Bacterial extracellular solute-binding protein K02064 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 415.0
TLS3_k127_4677989_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 401.0
TLS3_k127_4677989_15 Glycyl-tRNA synthetase alpha subunit K14164 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 397.0
TLS3_k127_4677989_16 deoxyribonuclease IV (phage-T4-induced) activity K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 389.0
TLS3_k127_4677989_17 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 385.0
TLS3_k127_4677989_18 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 376.0
TLS3_k127_4677989_19 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 360.0
TLS3_k127_4677989_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.374e-208 665.0
TLS3_k127_4677989_20 PFAM Shikimate quinate 5-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 364.0
TLS3_k127_4677989_21 TIGRFAM small GTP-binding protein K06945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 298.0
TLS3_k127_4677989_22 Protein of unknown function (DUF554) K07150 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 299.0
TLS3_k127_4677989_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 289.0
TLS3_k127_4677989_24 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001854 273.0
TLS3_k127_4677989_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001212 259.0
TLS3_k127_4677989_26 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002492 265.0
TLS3_k127_4677989_27 heme binding K21472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009982 261.0
TLS3_k127_4677989_28 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000002242 221.0
TLS3_k127_4677989_29 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000845 219.0
TLS3_k127_4677989_3 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 4.376e-206 651.0
TLS3_k127_4677989_30 4-vinyl reductase, 4VR - - - 0.00000000000000000000000000000000000000000000000000000000005328 211.0
TLS3_k127_4677989_31 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000001114 195.0
TLS3_k127_4677989_32 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000001586 195.0
TLS3_k127_4677989_33 PFAM Thiamin pyrophosphokinase, catalytic region K00949 - 2.7.6.2 0.000000000000000000000000000000000000000000000000003466 189.0
TLS3_k127_4677989_34 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000001547 180.0
TLS3_k127_4677989_35 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000002181 156.0
TLS3_k127_4677989_36 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.00000000000000000000000000000000000008888 149.0
TLS3_k127_4677989_37 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000001755 145.0
TLS3_k127_4677989_38 PFAM diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000000000000000005078 143.0
TLS3_k127_4677989_39 Yqey-like protein K09117 - - 0.0000000000000000000000000000000003678 136.0
TLS3_k127_4677989_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 4.402e-199 627.0
TLS3_k127_4677989_40 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000004707 134.0
TLS3_k127_4677989_41 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000001118 136.0
TLS3_k127_4677989_42 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000002089 128.0
TLS3_k127_4677989_43 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059,K03366 - 1.1.1.100,1.1.1.304,1.1.1.76 0.000000000000000000000000000008475 126.0
TLS3_k127_4677989_44 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000004763 123.0
TLS3_k127_4677989_45 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025,K20866 - 3.1.3.10 0.00000000000000000000000004501 115.0
TLS3_k127_4677989_46 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000005764 95.0
TLS3_k127_4677989_47 Transcriptional regulatory protein, C terminal - - - 0.00000001294 62.0
TLS3_k127_4677989_48 DinB superfamily - - - 0.0000002235 59.0
TLS3_k127_4677989_5 metal-dependent phosphohydrolase, HD sub domain K07037 - - 5.329e-199 642.0
TLS3_k127_4677989_50 - - - - 0.0007783 46.0
TLS3_k127_4677989_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 6.845e-199 627.0
TLS3_k127_4677989_7 Hexapeptide repeat of succinyl-transferase - - - 8.181e-195 616.0
TLS3_k127_4677989_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 585.0
TLS3_k127_4677989_9 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin K14645,K17734 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 518.0
TLS3_k127_4737359_0 secondary active sulfate transmembrane transporter activity K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 541.0
TLS3_k127_4737359_1 transferase activity, transferring glycosyl groups K21011,K21012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 295.0
TLS3_k127_4737359_10 transcriptional regulator - - - 0.0000000000000000000000000000000000000006101 155.0
TLS3_k127_4737359_11 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.000000000000000000000000000000001692 138.0
TLS3_k127_4737359_12 cog cog3323 - - - 0.000000000000000000000000000000003213 132.0
TLS3_k127_4737359_13 PFAM Calcium calmodulin dependent protein kinase II - - - 0.000000000000000000000000000000007266 132.0
TLS3_k127_4737359_14 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000003703 122.0
TLS3_k127_4737359_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 286.0
TLS3_k127_4737359_3 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001978 284.0
TLS3_k127_4737359_4 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005535 282.0
TLS3_k127_4737359_5 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000008619 257.0
TLS3_k127_4737359_6 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000003013 220.0
TLS3_k127_4737359_7 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000001933 227.0
TLS3_k127_4737359_9 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000000000007242 173.0
TLS3_k127_4739540_0 Class II Aldolase and Adducin N-terminal domain K01845 - 5.4.3.8 2.556e-229 718.0
TLS3_k127_4739540_1 FGGY family of carbohydrate kinases, C-terminal domain K00854 - 2.7.1.17 5.393e-195 621.0
TLS3_k127_4739540_2 DNA methylase - - - 0.00000000000000000000000000000000000000000000000000000000000000004729 237.0
TLS3_k127_4739540_3 Class II Aldolase and Adducin N-terminal domain K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000001203 224.0
TLS3_k127_4739540_4 - - - - 0.0000000000000000000000000000000000000000000000335 180.0
TLS3_k127_4739540_5 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000005201 147.0
TLS3_k127_4739540_6 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000005256 138.0
TLS3_k127_4749097_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 301.0
TLS3_k127_4749097_1 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000008862 235.0
TLS3_k127_4749097_2 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000007333 232.0
TLS3_k127_4749097_3 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000002461 234.0
TLS3_k127_4749097_4 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000004672 206.0
TLS3_k127_4749097_5 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000005534 195.0
TLS3_k127_4749097_6 rhs-related protein - - - 0.00000000002796 76.0
TLS3_k127_4761178_0 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000326 237.0
TLS3_k127_4761178_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000002325 144.0
TLS3_k127_4777341_0 peptidase M29 aminopeptidase II K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 459.0
TLS3_k127_4777341_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 364.0
TLS3_k127_4811976_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 618.0
TLS3_k127_4811976_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 574.0
TLS3_k127_4811976_10 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 441.0
TLS3_k127_4811976_11 PFAM ABC transporter related K01990,K16907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 402.0
TLS3_k127_4811976_12 Winged helix DNA-binding domain K09927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 367.0
TLS3_k127_4811976_13 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 359.0
TLS3_k127_4811976_14 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 359.0
TLS3_k127_4811976_15 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 353.0
TLS3_k127_4811976_16 Family 4 glycosyl hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 360.0
TLS3_k127_4811976_17 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 338.0
TLS3_k127_4811976_18 ATPase, P-type transporting, HAD superfamily, subfamily IC K16905 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 293.0
TLS3_k127_4811976_19 transmembrane transport K16906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006097 274.0
TLS3_k127_4811976_2 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 603.0
TLS3_k127_4811976_20 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000002032 259.0
TLS3_k127_4811976_21 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000002266 242.0
TLS3_k127_4811976_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000001377 219.0
TLS3_k127_4811976_23 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000004682 212.0
TLS3_k127_4811976_24 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000001027 180.0
TLS3_k127_4811976_25 membrane K07149 - - 0.00000000000000000000000000000000000004405 151.0
TLS3_k127_4811976_26 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000001087 139.0
TLS3_k127_4811976_27 Transcriptional regulator - - - 0.000000000000000000000000000000001227 139.0
TLS3_k127_4811976_29 Domain of unknown function (DUF3597) - - - 0.0000000000000000000000000001148 117.0
TLS3_k127_4811976_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 552.0
TLS3_k127_4811976_30 thiolester hydrolase activity K06889 - - 0.00000000000000000000000001078 116.0
TLS3_k127_4811976_31 serine-type peptidase activity - - - 0.0000000000000000000000003444 105.0
TLS3_k127_4811976_32 - - - - 0.0000000000000000000003682 111.0
TLS3_k127_4811976_33 - - - - 0.00000000000000003768 92.0
TLS3_k127_4811976_34 - - - - 0.000000000001493 70.0
TLS3_k127_4811976_37 Essential cell division protein K03589 - - 0.000121 53.0
TLS3_k127_4811976_38 serine-type peptidase activity - - - 0.0005921 45.0
TLS3_k127_4811976_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 539.0
TLS3_k127_4811976_5 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 525.0
TLS3_k127_4811976_6 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 496.0
TLS3_k127_4811976_7 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005119 483.0
TLS3_k127_4811976_8 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 469.0
TLS3_k127_4811976_9 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 459.0
TLS3_k127_483597_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847,K01848 - 5.4.99.2 1.952e-242 756.0
TLS3_k127_483597_1 PFAM Radical SAM domain protein K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 506.0
TLS3_k127_483597_3 Ceramidase - - - 0.0000000000000000000000000000000000000002681 159.0
TLS3_k127_484230_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1487.0
TLS3_k127_484230_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1182.0
TLS3_k127_484230_11 isoprenoid biosynthetic process K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000398 49.0
TLS3_k127_484230_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 558.0
TLS3_k127_484230_3 PFAM Adenosine AMP deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 426.0
TLS3_k127_484230_4 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001698 252.0
TLS3_k127_484230_5 Transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004184 252.0
TLS3_k127_484230_6 Histidine kinase - - - 0.0000000000000000001271 104.0
TLS3_k127_484230_7 helix_turn_helix, Lux Regulon K07693 - - 0.00000000000000002154 92.0
TLS3_k127_484230_8 Family of unknown function (DUF5317) - - - 0.00000000001631 73.0
TLS3_k127_484230_9 sequence-specific DNA binding - - - 0.000000005389 69.0
TLS3_k127_4862366_0 PFAM ABC transporter related K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 599.0
TLS3_k127_4862366_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 503.0
TLS3_k127_4862366_2 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 346.0
TLS3_k127_4862366_3 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 321.0
TLS3_k127_4862366_4 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 306.0
TLS3_k127_4862366_5 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000179 244.0
TLS3_k127_4862366_6 Cobalt transport protein K16785 - - 0.0000000000000000000000000000000000000000000000000000000000000000001996 239.0
TLS3_k127_4862366_7 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000003637 209.0
TLS3_k127_4862366_8 ECF-type riboflavin transporter, S component K16924 - - 0.0000000000000000000000000000000000000000000000000003474 190.0
TLS3_k127_4862366_9 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.0000000000000000000000000000000000000000000001133 174.0
TLS3_k127_487122_0 Serine threonine protein kinase K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 420.0
TLS3_k127_487122_1 N-acetylglucosaminylinositol deacetylase activity K22135 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 299.0
TLS3_k127_487122_10 SMART Glycoside hydrolase, family 25 subgroup K07273 - - 0.00000000000000000004426 106.0
TLS3_k127_487122_11 Bacterial SH3 domain - - - 0.00000000000002574 87.0
TLS3_k127_487122_12 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.00007396 54.0
TLS3_k127_487122_13 Putative sensor - - - 0.0005003 45.0
TLS3_k127_487122_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058,K21947 - 2.8.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 299.0
TLS3_k127_487122_3 glycosyl transferase group 1 K08256 - 2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 299.0
TLS3_k127_487122_4 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000164 265.0
TLS3_k127_487122_5 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000001897 198.0
TLS3_k127_487122_6 Phosphodiester glycosidase - - - 0.0000000000000000000000000000000000000000001165 183.0
TLS3_k127_487122_7 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.000000000000000000000000009675 115.0
TLS3_k127_487122_8 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000013 113.0
TLS3_k127_487122_9 guanyl-nucleotide exchange factor activity K20276 - - 0.000000000000000000000002311 115.0
TLS3_k127_4916191_0 nuclear chromosome segregation - - - 2.976e-251 800.0
TLS3_k127_4916191_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 458.0
TLS3_k127_4916191_11 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000008294 137.0
TLS3_k127_4916191_12 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000001217 119.0
TLS3_k127_4916191_13 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000009071 101.0
TLS3_k127_4916191_14 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000003839 93.0
TLS3_k127_4916191_16 Cna B domain protein - - - 0.00000000000007336 85.0
TLS3_k127_4916191_17 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000004361 60.0
TLS3_k127_4916191_18 translation initiation factor activity - - - 0.000013 57.0
TLS3_k127_4916191_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 381.0
TLS3_k127_4916191_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 346.0
TLS3_k127_4916191_4 PFAM phospholipase D Transphosphatidylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009772 259.0
TLS3_k127_4916191_5 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006903 246.0
TLS3_k127_4916191_6 PFAM histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000115 202.0
TLS3_k127_4916191_7 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000000000002674 185.0
TLS3_k127_4916191_8 Divergent PAP2 family K09775 - - 0.0000000000000000000000000000000000000000000000002321 179.0
TLS3_k127_4916191_9 methyltransferase activity K21310 - 2.1.1.334 0.00000000000000000000000000000000000000005353 158.0
TLS3_k127_4944007_0 ATPase AAA-2 domain protein K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006881 552.0
TLS3_k127_4944007_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 329.0
TLS3_k127_4944007_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000005713 265.0
TLS3_k127_4944007_3 - - - - 0.00000000000000000000000000005459 123.0
TLS3_k127_4944007_4 photosynthesis - - - 0.0004255 52.0
TLS3_k127_5000240_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2033.0
TLS3_k127_5000240_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1081.0
TLS3_k127_5000240_10 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006574 267.0
TLS3_k127_5000240_11 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001516 261.0
TLS3_k127_5000240_12 NAD-dependent epimerase dehydratase K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001787 263.0
TLS3_k127_5000240_13 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001691 240.0
TLS3_k127_5000240_14 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000009096 231.0
TLS3_k127_5000240_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000346 211.0
TLS3_k127_5000240_16 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000003757 214.0
TLS3_k127_5000240_17 Metallo-beta-lactamase superfamily K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000001487 183.0
TLS3_k127_5000240_18 - - - - 0.00000000000000000000000000000000000000001524 162.0
TLS3_k127_5000240_19 acetyltransferase K06889,K19273 - - 0.0000000000000000000000000000000000005173 145.0
TLS3_k127_5000240_2 PFAM cell divisionFtsK SpoIIIE K03466 - - 1.48e-212 682.0
TLS3_k127_5000240_20 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000157 118.0
TLS3_k127_5000240_21 - - - - 0.000001046 53.0
TLS3_k127_5000240_22 - - - - 0.000001204 51.0
TLS3_k127_5000240_3 N-terminal 7TM region of histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 580.0
TLS3_k127_5000240_4 HD domain K18967 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 528.0
TLS3_k127_5000240_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 434.0
TLS3_k127_5000240_6 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 395.0
TLS3_k127_5000240_7 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 314.0
TLS3_k127_5000240_8 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 292.0
TLS3_k127_5000240_9 PFAM RNA binding S1 domain protein K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001851 279.0
TLS3_k127_500279_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2090.0
TLS3_k127_500279_1 PFAM glycosyl transferase, family 51 - - - 0.0 1134.0
TLS3_k127_500279_10 sh3 domain protein K01448 - 3.5.1.28 0.0000009329 60.0
TLS3_k127_500279_11 domain protein - - - 0.000001253 59.0
TLS3_k127_500279_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 2.724e-275 872.0
TLS3_k127_500279_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009271 363.0
TLS3_k127_500279_5 Sodium calcium exchanger K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 362.0
TLS3_k127_500279_6 O-methyltransferase activity K00545 - 2.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 308.0
TLS3_k127_500279_7 MaoC like domain - - - 0.000000000000000000000000000000000000000000866 163.0
TLS3_k127_500279_8 Arylsulfatase a K01133 - 3.1.6.6 0.000000000000000000000000000000000203 139.0
TLS3_k127_500279_9 cobalamin binding - - - 0.000000000000000000000000000003628 121.0
TLS3_k127_5018384_0 peptidase activity - - - 3.033e-207 668.0
TLS3_k127_5018384_1 Extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 585.0
TLS3_k127_5018384_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 407.0
TLS3_k127_5018384_3 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 417.0
TLS3_k127_5018384_4 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 367.0
TLS3_k127_5018384_5 Belongs to the ABC transporter superfamily K02031,K15583,K16202 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 345.0
TLS3_k127_5018384_6 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 343.0
TLS3_k127_5018384_7 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000625 273.0
TLS3_k127_5033561_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 384.0
TLS3_k127_5033561_1 TAP-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 324.0
TLS3_k127_5033561_2 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000004954 243.0
TLS3_k127_5033561_3 PFAM ABC transporter K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000004038 226.0
TLS3_k127_5033561_4 OsmC-like protein K09136 - - 0.0000000000000000000000000000000000000000000000000000352 191.0
TLS3_k127_5033561_5 YacP-like NYN domain K06962 - - 0.00000000000000000000000000004413 121.0
TLS3_k127_5033561_8 Zinc finger domain - - - 0.0000000001016 72.0
TLS3_k127_5115440_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 577.0
TLS3_k127_5115440_1 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 565.0
TLS3_k127_5115440_10 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000003184 258.0
TLS3_k127_5115440_11 Thioesterase superfamily protein - - - 0.0000000000000000000000000000000000000000000000000000000000001089 226.0
TLS3_k127_5115440_12 FAD binding domain in molybdopterin dehydrogenase K03519,K12529 - 1.2.5.3 0.000000000000000000000000000000000000000000000000003358 193.0
TLS3_k127_5115440_13 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000002304 188.0
TLS3_k127_5115440_14 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 0.000000000000000000000000000000000000000000000003249 179.0
TLS3_k127_5115440_15 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.0000000000000000000000000000000000000000000003167 176.0
TLS3_k127_5115440_16 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.0000000000000000000000000000007552 126.0
TLS3_k127_5115440_17 - - - - 0.00000000000000000000000000006655 119.0
TLS3_k127_5115440_18 alcohol dehydrogenase - - - 0.000000000002251 68.0
TLS3_k127_5115440_2 Beta-lactamase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 497.0
TLS3_k127_5115440_3 Nacht domain K13730 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 471.0
TLS3_k127_5115440_4 Peptidase family C69 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 449.0
TLS3_k127_5115440_5 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 384.0
TLS3_k127_5115440_6 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 378.0
TLS3_k127_5115440_7 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 340.0
TLS3_k127_5115440_8 TIGRFAM F420-dependent oxidoreductase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 330.0
TLS3_k127_5115440_9 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 293.0
TLS3_k127_5171420_0 PFAM PUCC protein K08226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 406.0
TLS3_k127_5171420_1 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 304.0
TLS3_k127_5171420_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 298.0
TLS3_k127_5171420_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001693 275.0
TLS3_k127_5171420_4 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001969 261.0
TLS3_k127_5171420_5 TIGRFAM cysteine desulfurase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001666 244.0
TLS3_k127_5171420_6 PFAM regulatory protein, MerR - - - 0.000000000000000000000000003456 118.0
TLS3_k127_5171420_7 ABC-2 family transporter protein - - - 0.0001757 52.0
TLS3_k127_5192234_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 604.0
TLS3_k127_5192234_1 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 473.0
TLS3_k127_5192234_10 PFAM DSBA oxidoreductase - - - 0.00000000000000000000000000000000000000000000000002217 189.0
TLS3_k127_5192234_11 - - - - 0.0000000000000000000000000000000000000000000000002425 188.0
TLS3_k127_5192234_12 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000004404 118.0
TLS3_k127_5192234_13 - - - - 0.00000000000000004155 92.0
TLS3_k127_5192234_14 - - - - 0.000000000001875 70.0
TLS3_k127_5192234_15 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.0000002489 58.0
TLS3_k127_5192234_16 antisigma factor binding K04749 - - 0.00001164 54.0
TLS3_k127_5192234_2 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 435.0
TLS3_k127_5192234_3 ZIP Zinc transporter K07238,K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 405.0
TLS3_k127_5192234_4 PFAM ComEC Rec2-related protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 362.0
TLS3_k127_5192234_5 PFAM deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 313.0
TLS3_k127_5192234_6 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 328.0
TLS3_k127_5192234_7 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000005584 239.0
TLS3_k127_5192234_8 metal ion binding. It is involved in the biological process described with 'de novo' pyrimidine nucleobase biosynthetic process K11540 GO:0000050,GO:0000052,GO:0000166,GO:0001882,GO:0001884,GO:0002119,GO:0002134,GO:0002164,GO:0003674,GO:0003824,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0004672,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006220,GO:0006221,GO:0006228,GO:0006464,GO:0006468,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009605,GO:0009653,GO:0009719,GO:0009725,GO:0009791,GO:0009887,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0016053,GO:0016301,GO:0016310,GO:0016363,GO:0016597,GO:0016740,GO:0016741,GO:0016743,GO:0016772,GO:0016773,GO:0016787,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0017144,GO:0018107,GO:0018130,GO:0018193,GO:0018210,GO:0019103,GO:0019240,GO:0019438,GO:0019538,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0019899,GO:0022612,GO:0030424,GO:0030554,GO:0031406,GO:0031667,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0032868,GO:0032991,GO:0033267,GO:0034399,GO:0034404,GO:0034641,GO:0034654,GO:0035295,GO:0035639,GO:0036094,GO:0036211,GO:0036477,GO:0042221,GO:0042455,GO:0042594,GO:0042802,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043195,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043434,GO:0043436,GO:0043603,GO:0043604,GO:0043679,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044297,GO:0044306,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044456,GO:0044463,GO:0044464,GO:0045202,GO:0046051,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046394,GO:0046483,GO:0046777,GO:0046872,GO:0046914,GO:0048513,GO:0048565,GO:0048731,GO:0048732,GO:0048856,GO:0050896,GO:0055086,GO:0055123,GO:0060465,GO:0070013,GO:0070335,GO:0070406,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:0097458,GO:0098793,GO:0120025,GO:0120038,GO:0140096,GO:0150034,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901652,GO:1901657,GO:1901659,GO:1901698,GO:1901700,GO:1905905 2.1.3.2,3.5.2.3,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000002723 229.0
TLS3_k127_5192234_9 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000003344 189.0
TLS3_k127_5208612_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.592e-250 781.0
TLS3_k127_5208612_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 4.384e-248 774.0
TLS3_k127_5208612_10 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 456.0
TLS3_k127_5208612_11 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 408.0
TLS3_k127_5208612_12 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 399.0
TLS3_k127_5208612_13 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 391.0
TLS3_k127_5208612_14 PFAM Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 391.0
TLS3_k127_5208612_15 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009622 383.0
TLS3_k127_5208612_16 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 368.0
TLS3_k127_5208612_17 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 364.0
TLS3_k127_5208612_18 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 335.0
TLS3_k127_5208612_19 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 327.0
TLS3_k127_5208612_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.957e-224 703.0
TLS3_k127_5208612_20 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 321.0
TLS3_k127_5208612_21 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 327.0
TLS3_k127_5208612_22 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 319.0
TLS3_k127_5208612_23 Arylsulfatase a K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 306.0
TLS3_k127_5208612_24 Integral membrane protein DUF92 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 286.0
TLS3_k127_5208612_25 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007234 271.0
TLS3_k127_5208612_26 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000007148 265.0
TLS3_k127_5208612_27 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001157 258.0
TLS3_k127_5208612_28 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000002728 256.0
TLS3_k127_5208612_29 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000008879 219.0
TLS3_k127_5208612_3 uridine kinase K00876 - 2.7.1.48 1.699e-218 691.0
TLS3_k127_5208612_30 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000009201 218.0
TLS3_k127_5208612_31 WbqC-like protein family - - - 0.0000000000000000000000000000000000000000000000000000000003185 210.0
TLS3_k127_5208612_32 trans-aconitate 2-methyltransferase activity K02169 GO:0002682,GO:0002683,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0031347,GO:0031348,GO:0035821,GO:0043207,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046467,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0071704,GO:0075136,GO:0080134,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000004072 208.0
TLS3_k127_5208612_34 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000002101 179.0
TLS3_k127_5208612_35 Domain of unknown function (DUF4870) K09940 - - 0.0000000000000000000000000000000000000000000003501 171.0
TLS3_k127_5208612_36 Phosphoglycerate mutase family K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000001163 169.0
TLS3_k127_5208612_38 Major intrinsic protein - - - 0.000000000000000000000000000000000006837 146.0
TLS3_k127_5208612_39 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000001046 151.0
TLS3_k127_5208612_4 PFAM VanW family protein - - - 4.462e-205 655.0
TLS3_k127_5208612_40 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000000000000000000000002761 117.0
TLS3_k127_5208612_41 Cold shock protein domain K03704 - - 0.00000000000000000000000002141 112.0
TLS3_k127_5208612_42 Catalase domain protein K03781 - 1.11.1.6 0.000000000000000000000000038 108.0
TLS3_k127_5208612_43 Domain of unknown function (DUF4870) - - - 0.0000000000000211 77.0
TLS3_k127_5208612_45 Catalase domain protein K03781 - 1.11.1.6 0.0000000007086 61.0
TLS3_k127_5208612_46 HEAT repeat - - - 0.0000002249 59.0
TLS3_k127_5208612_5 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K02805 GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0005976,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016740,GO:0016769,GO:0019180,GO:0019842,GO:0030170,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046378,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901576 2.6.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 584.0
TLS3_k127_5208612_6 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006005 533.0
TLS3_k127_5208612_7 Aldo/keto reductase family K19265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 529.0
TLS3_k127_5208612_8 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 534.0
TLS3_k127_5208612_9 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 469.0
TLS3_k127_5213948_0 Alpha amylase, catalytic domain - - - 1.819e-311 981.0
TLS3_k127_5213948_1 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009276 273.0
TLS3_k127_5213948_2 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000001094 163.0
TLS3_k127_5213948_3 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000008212 160.0
TLS3_k127_5237151_0 Belongs to the formate--tetrahydrofolate ligase family K00288,K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.5.1.5,3.5.4.9,6.3.4.3 1.603e-265 826.0
TLS3_k127_5237151_1 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 489.0
TLS3_k127_5237151_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 418.0
TLS3_k127_5237151_3 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 352.0
TLS3_k127_5237151_4 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000553 190.0
TLS3_k127_5255298_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.788e-194 610.0
TLS3_k127_5255298_1 PFAM ABC transporter related K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 554.0
TLS3_k127_5255298_2 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 447.0
TLS3_k127_5255298_3 PFAM binding-protein-dependent transport systems inner membrane component K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 355.0
TLS3_k127_5255298_4 PFAM binding-protein-dependent transport systems inner membrane component K15772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 340.0
TLS3_k127_5255298_5 Sugar kinase of the NBD HSP70 family, may containing an N-terminal HTH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 331.0
TLS3_k127_5255298_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 327.0
TLS3_k127_5255298_7 PFAM extracellular solute-binding protein family 1 K15770 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 308.0
TLS3_k127_5255298_8 Alpha-amylase domain K01176 - 3.2.1.1 0.00000000000000000000000004797 113.0
TLS3_k127_5275966_0 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 531.0
TLS3_k127_5304672_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 504.0
TLS3_k127_5304672_1 COG4886 Leucine-rich repeat (LRR) protein - - - 0.00000000000000000000000000000000000000000000007343 171.0
TLS3_k127_5308448_0 Serine threonine protein kinase K12132 - 2.7.11.1 5.742e-281 875.0
TLS3_k127_5308448_1 Pyridoxal-phosphate dependent enzyme - - - 3.893e-253 787.0
TLS3_k127_5308448_10 PFAM peptidase M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 449.0
TLS3_k127_5308448_11 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 415.0
TLS3_k127_5308448_12 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 406.0
TLS3_k127_5308448_13 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 398.0
TLS3_k127_5308448_14 Two component transcriptional regulator, winged helix family K07667,K07668 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 376.0
TLS3_k127_5308448_15 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 378.0
TLS3_k127_5308448_16 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 358.0
TLS3_k127_5308448_17 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 334.0
TLS3_k127_5308448_18 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 298.0
TLS3_k127_5308448_19 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 301.0
TLS3_k127_5308448_2 PFAM carboxyl transferase - - - 3.655e-232 728.0
TLS3_k127_5308448_20 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 291.0
TLS3_k127_5308448_21 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002173 282.0
TLS3_k127_5308448_22 Peptidase family M20/M25/M40 K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001093 290.0
TLS3_k127_5308448_23 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005075 282.0
TLS3_k127_5308448_24 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004964 271.0
TLS3_k127_5308448_25 Hydrolase, alpha beta domain protein K01048 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000003233 259.0
TLS3_k127_5308448_26 DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000004326 241.0
TLS3_k127_5308448_27 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000005274 244.0
TLS3_k127_5308448_28 adenosine deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000002971 242.0
TLS3_k127_5308448_29 PFAM single-stranded nucleic acid binding R3H domain protein K06346 - - 0.00000000000000000000000000000000000000000000000000000000000000001177 233.0
TLS3_k127_5308448_3 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 7.746e-221 716.0
TLS3_k127_5308448_30 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000231 237.0
TLS3_k127_5308448_31 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000001931 214.0
TLS3_k127_5308448_32 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000003848 183.0
TLS3_k127_5308448_33 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000001046 187.0
TLS3_k127_5308448_34 PFAM dihydrodipicolinate synthetase K01714,K21062 - 3.5.4.22,4.3.3.7 0.000000000000000000000000000000000000000000000001341 185.0
TLS3_k127_5308448_35 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000002161 183.0
TLS3_k127_5308448_36 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000004661 174.0
TLS3_k127_5308448_37 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000001242 173.0
TLS3_k127_5308448_38 PFAM Forkhead-associated protein - - - 0.00000000000000000000000000000000000000000002633 169.0
TLS3_k127_5308448_39 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000000000000000004788 156.0
TLS3_k127_5308448_4 Two component regulator propeller K00936 - 2.7.13.3 3.364e-209 695.0
TLS3_k127_5308448_40 PFAM secretion protein HlyD family protein K01993 - - 0.00000000000000000000000000000000000000002259 169.0
TLS3_k127_5308448_41 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000003718 162.0
TLS3_k127_5308448_42 Histidine kinase - - - 0.0000000000000000000000000000000000000001891 174.0
TLS3_k127_5308448_43 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000007517 146.0
TLS3_k127_5308448_44 - - - - 0.000000000000000000000000000001811 131.0
TLS3_k127_5308448_45 - - - - 0.0000000000000000000000000818 108.0
TLS3_k127_5308448_46 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000004153 111.0
TLS3_k127_5308448_47 - - - - 0.00000000000000000000001596 102.0
TLS3_k127_5308448_48 PFAM biotin lipoyl attachment domain-containing protein - - - 0.00000000000000000000001958 106.0
TLS3_k127_5308448_5 PFAM TPR repeat-containing protein - - - 4.831e-205 662.0
TLS3_k127_5308448_50 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000006742 84.0
TLS3_k127_5308448_51 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000002222 79.0
TLS3_k127_5308448_52 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000003213 87.0
TLS3_k127_5308448_53 AAA domain K02282 - - 0.0000000000004901 81.0
TLS3_k127_5308448_54 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000003152 71.0
TLS3_k127_5308448_6 PFAM type II secretion system protein E K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 601.0
TLS3_k127_5308448_7 PFAM Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 571.0
TLS3_k127_5308448_8 Flotillin K07192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 567.0
TLS3_k127_5308448_9 PFAM Amidohydrolase 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 559.0
TLS3_k127_5318201_0 Histidine kinase-like ATPases - - - 4.601e-207 656.0
TLS3_k127_5318201_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 355.0
TLS3_k127_5318201_2 Histidine kinase A domain protein - - - 0.00000000000000001339 89.0
TLS3_k127_5318946_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 354.0
TLS3_k127_5318946_1 PFAM ABC transporter related K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001084 278.0
TLS3_k127_5318946_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.0000000000000000000000000000000000000000000001061 174.0
TLS3_k127_5318946_3 - - - - 0.000000000000000000000000000000006085 138.0
TLS3_k127_5318946_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000001502 73.0
TLS3_k127_5318946_5 domain protein associated with RNAses G and E K07586 - - 0.00000003397 63.0
TLS3_k127_5318979_0 Enoyl-(Acyl carrier protein) reductase K10780 - 1.3.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 319.0
TLS3_k127_5318979_1 adenosylmethionine-8-amino-7-oxononanoate transaminase activity K15372 - 2.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 298.0
TLS3_k127_5318979_2 - - - - 0.000000000000000000000000000000000000000000000000003422 187.0
TLS3_k127_5318979_3 Domain of unknown function (DUF309) K09763 - - 0.00000000000000000000000000000004413 134.0
TLS3_k127_5327128_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1767.0
TLS3_k127_5327128_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 427.0
TLS3_k127_5327128_2 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000002447 130.0
TLS3_k127_5327128_3 by Glimmer3 - - - 0.0000000000000000000009386 94.0
TLS3_k127_5327128_4 Ribosomal protein S21 K02970 - - 0.0000000000000000001819 89.0
TLS3_k127_5327128_5 - - - - 0.0000002931 52.0
TLS3_k127_5327128_6 - - - - 0.0000695 46.0
TLS3_k127_5337534_0 succinyl-diaminopimelate desuccinylase activity K01439 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 0.0 1174.0
TLS3_k127_5337534_1 Aminotransferase K00812 - 2.6.1.1 5.23e-200 631.0
TLS3_k127_5337534_10 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000001193 83.0
TLS3_k127_5337534_11 Prolyl oligopeptidase K01322 - 3.4.21.26 0.00000000000007735 72.0
TLS3_k127_5337534_2 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 499.0
TLS3_k127_5337534_3 PFAM Sporulation stage II, protein E C-terminal K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000002479 258.0
TLS3_k127_5337534_4 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000327 256.0
TLS3_k127_5337534_5 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000141 185.0
TLS3_k127_5337534_6 CHAT domain - - - 0.000000000000000000001694 109.0
TLS3_k127_5337534_7 PFAM histidine triad (HIT) protein - - - 0.0000000000000000009169 92.0
TLS3_k127_5337534_8 translation initiation factor activity K06996 - - 0.00000000000000000146 89.0
TLS3_k127_5337534_9 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000001942 100.0
TLS3_k127_5353976_0 TIGRFAM iron-sulfur cluster binding protein K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 358.0
TLS3_k127_5353976_1 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000000000000000000009043 207.0
TLS3_k127_5353976_2 phosphatase - - - 0.000000000000000000000000000000000000000002564 161.0
TLS3_k127_5379506_0 intracellular signal transduction - - - 0.0 1236.0
TLS3_k127_5379506_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 427.0
TLS3_k127_5379506_2 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000003962 175.0
TLS3_k127_5390324_0 TIGRFAM alpha-glucan phosphorylases K00688 - 2.4.1.1 1.146e-234 746.0
TLS3_k127_5390324_1 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 344.0
TLS3_k127_5390324_2 energy transducer activity K03531,K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 319.0
TLS3_k127_5390324_3 DSBA-like thioredoxin domain - - - 0.00000000000000000008496 91.0
TLS3_k127_5390324_4 Rhodanese Homology Domain - - - 0.000000000000000007071 87.0
TLS3_k127_5390324_5 - - - - 0.00000000000000003512 84.0
TLS3_k127_5392766_0 PFAM aminotransferase class V K04127 - 5.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 454.0
TLS3_k127_5392766_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008544 322.0
TLS3_k127_5392766_2 - - - - 0.00000000000000000000000000000000000000000000000000000009852 204.0
TLS3_k127_5392766_3 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000207 197.0
TLS3_k127_5397332_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.265e-289 906.0
TLS3_k127_5397332_1 CO dehydrogenase flavoprotein C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 581.0
TLS3_k127_5397332_2 DeoC/LacD family aldolase K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000491 258.0
TLS3_k127_5397332_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002335 250.0
TLS3_k127_5397332_4 succinylglutamate desuccinylase aspartoacylase K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000002123 243.0
TLS3_k127_5397332_5 - - - - 0.0000000000000000000000000000000000000000000002409 172.0
TLS3_k127_5397332_6 PFAM DinB family protein - - - 0.0000000000000000000000000000000000000001462 161.0
TLS3_k127_5397332_7 Protein of unknown function (DUF1361) - - - 0.00000000000000000000000000000000000242 149.0
TLS3_k127_5473712_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000805 251.0
TLS3_k127_5473712_1 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000001686 238.0
TLS3_k127_5473712_2 Predicted integral membrane protein (DUF2270) - - - 0.00000000000000000000000000000000000000000000000000000000123 214.0
TLS3_k127_5473712_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000002018 183.0
TLS3_k127_5473712_4 Permease family K02824 - - 0.00000000000000003935 82.0
TLS3_k127_5473712_5 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.000000000000001944 88.0
TLS3_k127_5491448_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 581.0
TLS3_k127_5491448_1 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 535.0
TLS3_k127_5491448_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 503.0
TLS3_k127_5491448_3 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 437.0
TLS3_k127_5491448_4 Domain of unknown function DUF11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 371.0
TLS3_k127_5491448_5 Cna B domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 365.0
TLS3_k127_5491448_6 PFAM ROK family protein K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 315.0
TLS3_k127_5491448_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000007013 269.0
TLS3_k127_5491448_8 TIR domain - - - 0.0000000000000000000000000000000005835 138.0
TLS3_k127_5493737_0 penicillin amidase K01434 - 3.5.1.11 5.714e-306 960.0
TLS3_k127_5493737_1 Dienelactone hydrolase family - - - 2.067e-261 820.0
TLS3_k127_5493737_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000003283 207.0
TLS3_k127_5493737_11 Protein of unknown function (DUF1461) - - - 0.000000000000000000000000000000000000000000000009056 180.0
TLS3_k127_5493737_12 Asp23 family, cell envelope-related function - - - 0.00000000000000000000000000001152 127.0
TLS3_k127_5493737_13 protein secretion K03116,K03117 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000001564 61.0
TLS3_k127_5493737_15 VanZ like family - - - 0.00000008574 59.0
TLS3_k127_5493737_3 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 543.0
TLS3_k127_5493737_4 Spermine/spermidine synthase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 545.0
TLS3_k127_5493737_5 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 443.0
TLS3_k127_5493737_6 Domain of unknown function (DUF368) K08974 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 304.0
TLS3_k127_5493737_7 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003872 283.0
TLS3_k127_5493737_8 Putative FMN-binding domain K07734 - - 0.000000000000000000000000000000000000000000000000000000007065 205.0
TLS3_k127_5493737_9 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000009674 200.0
TLS3_k127_551875_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 4.419e-267 835.0
TLS3_k127_551875_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 486.0
TLS3_k127_551875_10 mitochondrial respiratory chain complex IV assembly K14998 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 - 0.0000000000000000000000000000000000000000000008968 174.0
TLS3_k127_551875_12 Belongs to the HAD-like hydrolase superfamily K01101 - 3.1.3.41 0.0000000000000000000000001765 109.0
TLS3_k127_551875_2 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 347.0
TLS3_k127_551875_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 318.0
TLS3_k127_551875_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 304.0
TLS3_k127_551875_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006788 285.0
TLS3_k127_551875_6 PFAM cytochrome c oxidase, subunit III K02276,K02299 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000001049 230.0
TLS3_k127_551875_7 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000003392 218.0
TLS3_k127_551875_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000345 208.0
TLS3_k127_551875_9 Electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000003542 188.0
TLS3_k127_5540262_0 phosphorelay sensor kinase activity K01768,K02482,K02584,K07673,K10819 - 2.7.13.3,4.6.1.1 0.000000000000000000000000000000000000000000003783 176.0
TLS3_k127_5540262_1 N-terminal 7TM region of histidine kinase - - - 0.0000000000000000000000006125 115.0
TLS3_k127_5540262_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000003896 71.0
TLS3_k127_5601777_0 Binding-protein-dependent transport system inner membrane component K02063 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 467.0
TLS3_k127_5601777_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007916 398.0
TLS3_k127_5601777_10 Anaphase-promoting complex subunit 5 - - - 0.00004146 55.0
TLS3_k127_5601777_2 TOBE domain K02062,K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 339.0
TLS3_k127_5601777_3 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000001237 205.0
TLS3_k127_5601777_4 Predicted membrane protein (DUF2085) - - - 0.00000000000000000000000000000000000000000000000002173 191.0
TLS3_k127_5601777_5 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000003047 182.0
TLS3_k127_5601777_6 PFAM ATP-binding region, ATPase domain protein K02486 - 2.7.13.3 0.000000000000000000000000000000991 135.0
TLS3_k127_5601777_7 Protein of unknown function (DUF402) K07586 - - 0.00000000000000000000000000001032 124.0
TLS3_k127_5601777_8 helix_turn_helix, Lux Regulon - - - 0.000000000000000002631 93.0
TLS3_k127_5601777_9 Diguanylate cyclase - - - 0.000000000000006509 76.0
TLS3_k127_5608963_0 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 364.0
TLS3_k127_5608963_1 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000341 273.0
TLS3_k127_5608963_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000001975 164.0
TLS3_k127_5608963_3 Alkaline and neutral invertase - - - 0.0000000000000000002433 102.0
TLS3_k127_5610737_0 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 328.0
TLS3_k127_5610737_1 Predicted membrane protein (DUF2085) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 305.0
TLS3_k127_5610737_2 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002785 289.0
TLS3_k127_5610737_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002253 251.0
TLS3_k127_5610737_4 PFAM Patatin K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000163 240.0
TLS3_k127_5610737_5 PFAM phospholipase Carboxylesterase K06999 - - 0.000000000000000000000000000000003133 136.0
TLS3_k127_5610737_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000001835 80.0
TLS3_k127_5610737_7 Cysteine-rich secretory protein family - - - 0.0000000000000005292 87.0
TLS3_k127_5618686_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 2.007e-226 706.0
TLS3_k127_5618686_1 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 3.42e-211 661.0
TLS3_k127_5618686_2 Oligoendopeptidase, pepF M3 family - - - 0.0000000000000000000000000000000000000000000000276 173.0
TLS3_k127_5618686_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000007905 129.0
TLS3_k127_5618686_4 Enoyl-CoA hydratase isomerase K15866 - 5.3.3.18 0.00000000000001498 77.0
TLS3_k127_5618686_5 domain protein - - - 0.000004012 53.0
TLS3_k127_5618686_6 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide - - - 0.00001591 47.0
TLS3_k127_5621849_0 PFAM ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 523.0
TLS3_k127_5621849_1 ABC transporter, transmembrane region K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 507.0
TLS3_k127_5621849_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K19694 - - 0.000000000000000000000000000000159 132.0
TLS3_k127_5621849_12 - - - - 0.0000000000000000000000002575 111.0
TLS3_k127_5621849_13 hydrogenase maturation protease K08315 - 3.4.23.51 0.000000000000000000000001058 111.0
TLS3_k127_5621849_14 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000001269 100.0
TLS3_k127_5621849_15 LysM domain K06194 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - 0.000000001104 70.0
TLS3_k127_5621849_16 AsnC family - - - 0.000000005532 59.0
TLS3_k127_5621849_2 quinone binding K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 400.0
TLS3_k127_5621849_3 Formate/nitrite transporter K06212 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 338.0
TLS3_k127_5621849_4 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008539 339.0
TLS3_k127_5621849_5 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000001132 275.0
TLS3_k127_5621849_6 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K14090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001691 242.0
TLS3_k127_5621849_7 major facilitator superfamily MFS_1 K08226 - - 0.0000000000000000000000000000000000000000000000000000000001218 220.0
TLS3_k127_5621849_8 4Fe-4S binding domain K14091 - - 0.00000000000000000000000000000000000000000000004548 179.0
TLS3_k127_5621849_9 Domain of unknown function (DUF4491) - - - 0.00000000000000000000000000000000007983 136.0
TLS3_k127_5662995_0 Spermidine synthase tetramerisation domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000763 424.0
TLS3_k127_5662995_1 glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 340.0
TLS3_k127_5662995_2 Phospholipase/Carboxylesterase K06999,K15975 - - 0.000000000000000000000000000000000000000000000000000000000000000000009606 241.0
TLS3_k127_5662995_3 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000001314 116.0
TLS3_k127_566414_0 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 487.0
TLS3_k127_566414_1 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 364.0
TLS3_k127_566414_2 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000006644 264.0
TLS3_k127_566414_3 peptidase dimerisation domain protein K01436 - - 0.0000000000000000000000000000000000000000000000000008662 190.0
TLS3_k127_566414_4 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000001154 135.0
TLS3_k127_56885_0 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 303.0
TLS3_k127_56885_1 Peptidase MA superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005202 258.0
TLS3_k127_56885_2 PFAM Auxin Efflux Carrier K07088 - - 0.000000000000000000000000000000000000000000000006254 184.0
TLS3_k127_56885_3 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000007083 87.0
TLS3_k127_5695282_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 508.0
TLS3_k127_5695282_1 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000006991 196.0
TLS3_k127_5695282_2 Regulatory protein, FmdB family - - - 0.000000000000000000005627 96.0
TLS3_k127_5695282_3 Major facilitator Superfamily - - - 0.0000000000000000000168 93.0
TLS3_k127_5695282_4 Rdx family K07401 - - 0.00000000000008699 72.0
TLS3_k127_5700609_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 601.0
TLS3_k127_5700609_1 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 399.0
TLS3_k127_5700609_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 360.0
TLS3_k127_5700609_3 ABC transporter K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 308.0
TLS3_k127_5700609_4 Amidinotransferase K01482 - 3.5.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 288.0
TLS3_k127_5700609_5 ABC transporter, permease protein K02029,K02030,K09971,K17062 - - 0.00000000000000000000000000000000000000000000000000000002196 207.0
TLS3_k127_5700609_6 amino acid transport K02030 - - 0.00000000000000000000000000000000000000000000000000005101 199.0
TLS3_k127_5700609_7 Protein of unknown function (DUF3788) - - - 0.00000000000000000000000000000003981 130.0
TLS3_k127_5700609_8 SCP-2 sterol transfer family - - - 0.00000000000000000000000004144 113.0
TLS3_k127_5738204_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 2.737e-219 694.0
TLS3_k127_5738204_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 1.392e-196 619.0
TLS3_k127_5738204_10 Biotin/lipoate A/B protein ligase family K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000001714 174.0
TLS3_k127_5738204_11 diguanylate cyclase - - - 0.000000000000000000000000000000000000001118 164.0
TLS3_k127_5738204_12 diguanylate cyclase - - - 0.000000000000000000000000000000000000005086 158.0
TLS3_k127_5738204_13 Thi4 family - - - 0.00000000000000000000000000000000001683 137.0
TLS3_k127_5738204_14 methyltransferase K18846 - 2.1.1.180 0.0000000000000000000001454 106.0
TLS3_k127_5738204_15 HIT family hydrolase K02503 - - 0.00000000005157 68.0
TLS3_k127_5738204_16 - - - - 0.00006916 51.0
TLS3_k127_5738204_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 471.0
TLS3_k127_5738204_3 FAD linked oxidase domain protein K00103,K16653 GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576 1.1.3.8,1.1.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 453.0
TLS3_k127_5738204_4 Helicase conserved C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 446.0
TLS3_k127_5738204_5 PFAM diacylglycerol kinase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 325.0
TLS3_k127_5738204_6 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 - 2.4.2.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003164 279.0
TLS3_k127_5738204_7 PFAM peptidase, membrane zinc metallopeptidase K06973 - - 0.0000000000000000000000000000000000000000000000000000000000001885 219.0
TLS3_k127_5738204_8 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000001722 212.0
TLS3_k127_5738204_9 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000000000000001312 199.0
TLS3_k127_5879994_0 xylulokinase activity K00848,K00851,K00854,K00862 - 2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5 8.42e-273 847.0
TLS3_k127_5879994_1 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 551.0
TLS3_k127_5879994_2 udp-glucose 4-epimerase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 524.0
TLS3_k127_5879994_3 L-ribulose-5-phosphate 4-epimerase K03077 - 5.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008546 382.0
TLS3_k127_5879994_4 posttranslational protein targeting to endoplasmic reticulum membrane - - - 0.000000000000000000000000000000000000000002575 157.0
TLS3_k127_5879994_5 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 0.0000000000000000000000000000000000000001896 153.0
TLS3_k127_5972807_0 Peptidase dimerisation domain - - - 2.011e-212 664.0
TLS3_k127_5972807_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K09065 - 2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 524.0
TLS3_k127_5972807_10 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008366 329.0
TLS3_k127_5972807_11 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 318.0
TLS3_k127_5972807_12 PFAM ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 293.0
TLS3_k127_5972807_13 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002417 271.0
TLS3_k127_5972807_14 alpha-ribazole phosphatase activity - - - 0.00000000000000000000000000000000000357 143.0
TLS3_k127_5972807_15 UTRA K03710 - - 0.0000000000000000000001722 106.0
TLS3_k127_5972807_2 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 506.0
TLS3_k127_5972807_3 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000769 449.0
TLS3_k127_5972807_4 PFAM Basic membrane K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 445.0
TLS3_k127_5972807_6 ABC transporter substrate-binding protein PnrA-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 358.0
TLS3_k127_5972807_7 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 344.0
TLS3_k127_5972807_8 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 334.0
TLS3_k127_5972807_9 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007917 335.0
TLS3_k127_6038730_0 GDP-mannose mannosyl hydrolase activity K01515,K03574,K13669,K19710 GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.53,3.6.1.13,3.6.1.55 0.00000000000000000000000000000000000000000000004304 175.0
TLS3_k127_6038730_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000389 151.0
TLS3_k127_6073521_0 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007427 329.0
TLS3_k127_6073521_1 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000001463 239.0
TLS3_k127_6073521_3 PFAM aspartate glutamate uridylate kinase K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000000000000000003187 232.0
TLS3_k127_6073521_4 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000001126 195.0
TLS3_k127_6073521_5 Belongs to the formate--tetrahydrofolate ligase family K00288,K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.5.1.5,3.5.4.9,6.3.4.3 0.00000000000000000000000000000000000000000001029 167.0
TLS3_k127_6073521_6 PHP-associated - - - 0.0000000000000000000000000000000000000000003794 166.0
TLS3_k127_6073521_8 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00007584 55.0
TLS3_k127_6077530_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 428.0
TLS3_k127_6077530_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 333.0
TLS3_k127_6077530_2 Baseplate J-like protein K01218 - 3.2.1.78 0.000000000000000000000000000000000000000000000000009816 194.0
TLS3_k127_6077530_3 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000001148 186.0
TLS3_k127_6141168_0 Parallel beta-helix repeats - - - 1.897e-211 714.0
TLS3_k127_6141168_1 ABC transporter related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 509.0
TLS3_k127_6141168_10 - - - - 0.0000000000000002443 83.0
TLS3_k127_6141168_11 Protein of unknown function (DUF3179) - - - 0.00000000188 63.0
TLS3_k127_6141168_12 Condensation domain - - - 0.0000005165 62.0
TLS3_k127_6141168_13 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.000003301 55.0
TLS3_k127_6141168_14 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000005592 57.0
TLS3_k127_6141168_16 - - - - 0.00004705 51.0
TLS3_k127_6141168_2 Phage Tail Collar Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 284.0
TLS3_k127_6141168_3 Phage Tail Collar Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008723 273.0
TLS3_k127_6141168_4 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001048 277.0
TLS3_k127_6141168_5 Phage Tail Collar Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003136 259.0
TLS3_k127_6141168_6 Protein of unknown function (DUF3179) - - - 0.0000000000000000000000000000000000000000000002469 174.0
TLS3_k127_6141168_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000009894 170.0
TLS3_k127_6141168_8 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000006634 124.0
TLS3_k127_6141168_9 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.7.8.7 0.0000000000000000000000000003196 117.0
TLS3_k127_6153321_0 PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00335,K05587 - 1.6.5.3 4.346e-315 972.0
TLS3_k127_6153321_1 PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00335,K05587 - 1.6.5.3 7.32e-251 783.0
TLS3_k127_6153321_10 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000001143 144.0
TLS3_k127_6153321_11 DRTGG domain - - - 0.00000000000000000000000000000000009123 136.0
TLS3_k127_6153321_12 DRTGG domain - - - 0.000000000000000000000000000000003075 132.0
TLS3_k127_6153321_2 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 521.0
TLS3_k127_6153321_3 PFAM ATP-binding region, ATPase domain protein K17752 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 385.0
TLS3_k127_6153321_4 PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000007663 256.0
TLS3_k127_6153321_5 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334,K05586 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000008152 237.0
TLS3_k127_6153321_6 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000004337 224.0
TLS3_k127_6153321_7 2 iron, 2 sulfur cluster binding K00334 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000000000000000000006614 190.0
TLS3_k127_6153321_8 phosphorelay sensor kinase activity K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000001186 188.0
TLS3_k127_6153321_9 Ferredoxin K00335,K17992 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000011 150.0
TLS3_k127_617541_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 562.0
TLS3_k127_617541_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 554.0
TLS3_k127_617541_2 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 535.0
TLS3_k127_617541_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007605 461.0
TLS3_k127_6215955_0 PFAM Exonuclease, RNase T and DNA polymerase III K02342,K03722 - 2.7.7.7,3.6.4.12 0.0 1088.0
TLS3_k127_6215955_1 - - - - 0.000000000000000000000000000000000000000000002228 172.0
TLS3_k127_6220181_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 1.744e-257 807.0
TLS3_k127_6220181_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 9.894e-230 727.0
TLS3_k127_6220181_10 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 340.0
TLS3_k127_6220181_11 PFAM EAL domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 326.0
TLS3_k127_6220181_12 sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000828 250.0
TLS3_k127_6220181_13 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000000000000000000004375 210.0
TLS3_k127_6220181_14 Nudix hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000002874 206.0
TLS3_k127_6220181_15 PFAM Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000003658 196.0
TLS3_k127_6220181_16 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000001673 183.0
TLS3_k127_6220181_17 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000000000000000005352 149.0
TLS3_k127_6220181_18 DinB family - - - 0.000000000000000000000000000000003873 134.0
TLS3_k127_6220181_19 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000003967 129.0
TLS3_k127_6220181_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.486e-201 636.0
TLS3_k127_6220181_20 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000001176 134.0
TLS3_k127_6220181_22 Rhodanese Homology Domain - - - 0.00000000000000000000000001963 112.0
TLS3_k127_6220181_24 AntiSigma factor - - - 0.000000000007916 74.0
TLS3_k127_6220181_25 - - - - 0.00007723 49.0
TLS3_k127_6220181_26 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0001854 49.0
TLS3_k127_6220181_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 593.0
TLS3_k127_6220181_4 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 575.0
TLS3_k127_6220181_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009238 439.0
TLS3_k127_6220181_6 Clostripain family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 439.0
TLS3_k127_6220181_7 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 358.0
TLS3_k127_6220181_8 PFAM YbbR family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 359.0
TLS3_k127_6220181_9 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 343.0
TLS3_k127_6233473_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 610.0
TLS3_k127_6233473_1 TIGRFAM FeS assembly protein SufB K07033,K09014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 593.0
TLS3_k127_6233473_11 - - - - 0.00000000000000000000000000000000006523 140.0
TLS3_k127_6233473_12 PFAM Rieske 2Fe-2S domain protein K00363,K05710 - 1.7.1.15 0.0000000000000000000000000000000001722 135.0
TLS3_k127_6233473_13 Acetyltransferase (GNAT) domain K00657 - 2.3.1.57 0.0000000000000000000000000000731 122.0
TLS3_k127_6233473_14 - - - - 0.0000000000000001027 87.0
TLS3_k127_6233473_2 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 598.0
TLS3_k127_6233473_3 TIGRFAM FeS assembly protein SufD K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 581.0
TLS3_k127_6233473_4 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 482.0
TLS3_k127_6233473_5 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 460.0
TLS3_k127_6233473_6 PFAM Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 379.0
TLS3_k127_6233473_7 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 306.0
TLS3_k127_6233473_8 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 299.0
TLS3_k127_6233473_9 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000000000000000000000000000003832 209.0
TLS3_k127_6258536_0 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 318.0
TLS3_k127_6258536_2 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001916 278.0
TLS3_k127_6258536_3 Orotidine-5-phosphate decarboxylase orotate phosphoribosyltransferase K01591,K13421 - 2.4.2.10,4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000877 218.0
TLS3_k127_6258536_4 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000008505 181.0
TLS3_k127_6258536_5 Domain of unknown function (DUF1905) - - - 0.0000000000000000000000000000000000001991 145.0
TLS3_k127_6258536_7 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000001571 132.0
TLS3_k127_6258536_8 Orotidine 5'-phosphate decarboxylase / HUMPS family K13421 - 2.4.2.10,4.1.1.23 0.000000000000000000000002801 104.0
TLS3_k127_6287194_0 4-phosphoerythronate dehydrogenase activity K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000603 456.0
TLS3_k127_6287194_1 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 399.0
TLS3_k127_6287194_10 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000005629 182.0
TLS3_k127_6287194_12 - - - - 0.0006402 52.0
TLS3_k127_6287194_2 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 374.0
TLS3_k127_6287194_3 Glycosyl transferase, family 2 K00786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 372.0
TLS3_k127_6287194_4 PFAM glycosyl transferase, family 51 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 346.0
TLS3_k127_6287194_5 Protein of unknown function DUF115 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 337.0
TLS3_k127_6287194_6 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 301.0
TLS3_k127_6287194_7 cytidylyl-transferase K00983 - 2.7.7.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 292.0
TLS3_k127_6287194_8 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001108 247.0
TLS3_k127_6287194_9 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000001844 214.0
TLS3_k127_6362464_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1402.0
TLS3_k127_6362464_1 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 3.138e-212 679.0
TLS3_k127_6362464_10 Exopolysaccharide synthesis, ExoD - - - 0.0000000000000000000000000000000000000000000000000000000000003548 217.0
TLS3_k127_6362464_11 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) - - - 0.00000000000000000000000000000000000000000000000000000002228 205.0
TLS3_k127_6362464_12 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.000000000000000000000000000000000000000000000000001252 191.0
TLS3_k127_6362464_13 Domain of unknown function (DUF1998) K02336,K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.7.7.7 0.00000000000000000000000000000000000000000001055 168.0
TLS3_k127_6362464_14 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000000000000000000281 169.0
TLS3_k127_6362464_15 Transposase IS200 like - - - 0.0000000000000000000000000000000000000001103 154.0
TLS3_k127_6362464_16 Ribosomal L27 protein K02899 - - 0.0000000000000000000000000000000004233 132.0
TLS3_k127_6362464_17 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000000001244 132.0
TLS3_k127_6362464_18 phosphorelay signal transduction system - - - 0.0000000000000000000000000000001221 129.0
TLS3_k127_6362464_19 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.00004516 48.0
TLS3_k127_6362464_2 DNA helicase - - - 1.842e-207 666.0
TLS3_k127_6362464_3 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 535.0
TLS3_k127_6362464_4 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 409.0
TLS3_k127_6362464_5 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 364.0
TLS3_k127_6362464_6 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 349.0
TLS3_k127_6362464_7 PFAM thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 286.0
TLS3_k127_6362464_8 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001585 268.0
TLS3_k127_6362464_9 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000003403 253.0
TLS3_k127_6416857_0 Oligopeptidase F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 520.0
TLS3_k127_6416857_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009886 459.0
TLS3_k127_6416857_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 382.0
TLS3_k127_6416857_3 - - - - 0.000000000000000000000000000000009527 134.0
TLS3_k127_6416857_4 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.000000000000004601 78.0
TLS3_k127_6456934_0 PHP domain protein K02347 - - 1.121e-198 634.0
TLS3_k127_6456934_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 323.0
TLS3_k127_6456934_2 PFAM Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000000000007203 187.0
TLS3_k127_6456934_3 Putative inner membrane exporter, YdcZ K09936 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000004849 121.0
TLS3_k127_6456934_4 - - - - 0.00001114 53.0
TLS3_k127_6470955_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain - - - 9.182e-235 734.0
TLS3_k127_6470955_1 PFAM single-stranded nucleic acid binding R3H domain protein - - - 4.381e-221 696.0
TLS3_k127_6470955_10 Belongs to the UPF0271 (lamB) family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000004797 236.0
TLS3_k127_6470955_11 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000009436 207.0
TLS3_k127_6470955_12 Allophanate hydrolase subunit 2 K06350 - - 0.00000000000000000000000000000000000000000000000000007467 198.0
TLS3_k127_6470955_13 Allophanate hydrolase subunit 1 K01457,K06351,K07160 - 3.5.1.54 0.00000000000000000000000000000000000000003507 154.0
TLS3_k127_6470955_14 - - - - 0.000000000000000001104 91.0
TLS3_k127_6470955_16 Protein of unknown function (DUF1706) - - - 0.000000000000007633 81.0
TLS3_k127_6470955_17 Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.0000000007649 70.0
TLS3_k127_6470955_18 E3 Ubiquitin ligase - - - 0.00000135 60.0
TLS3_k127_6470955_19 Domain of unknown function (DUF389) - - - 0.00004813 55.0
TLS3_k127_6470955_2 Castor and Pollux, part of voltage-gated ion channel - - - 7.71e-197 638.0
TLS3_k127_6470955_3 Carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 482.0
TLS3_k127_6470955_4 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 399.0
TLS3_k127_6470955_5 PFAM oxidoreductase, molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 354.0
TLS3_k127_6470955_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 310.0
TLS3_k127_6470955_7 Heat shock protein DnaJ domain protein K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 300.0
TLS3_k127_6470955_8 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000003136 267.0
TLS3_k127_6470955_9 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000005463 258.0
TLS3_k127_6508530_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 471.0
TLS3_k127_6508530_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000001331 198.0
TLS3_k127_6512748_0 modification enzyme, MiaB family K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 512.0
TLS3_k127_6512748_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 489.0
TLS3_k127_6512748_10 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000002049 142.0
TLS3_k127_6512748_12 Putative sensor - - - 0.0000000000000000001942 92.0
TLS3_k127_6512748_13 Peptidoglycan-binding lysin domain - - - 0.0000002776 61.0
TLS3_k127_6512748_2 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 411.0
TLS3_k127_6512748_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 371.0
TLS3_k127_6512748_4 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 351.0
TLS3_k127_6512748_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075,K15780 - 2.4.2.8,6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 334.0
TLS3_k127_6512748_6 PFAM GDSL-like Lipase Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000006892 237.0
TLS3_k127_6512748_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000002037 188.0
TLS3_k127_6512748_8 cell envelope-related transcriptional attenuator - - - 0.000000000000000000000000000000000000000000000001018 192.0
TLS3_k127_6512748_9 PadR family transcriptional regulator K10947 - - 0.00000000000000000000000000000000000000534 148.0
TLS3_k127_6564927_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 1.743e-245 766.0
TLS3_k127_6564927_1 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009484 364.0
TLS3_k127_6564927_2 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000007308 239.0
TLS3_k127_6564927_3 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000242 169.0
TLS3_k127_6568688_0 Major Facilitator Superfamily K18833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 501.0
TLS3_k127_6568688_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000001122 217.0
TLS3_k127_6568688_2 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000001574 195.0
TLS3_k127_6568688_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000004433 104.0
TLS3_k127_6568688_4 Glyoxalase-like domain - - - 0.0000001996 56.0
TLS3_k127_6568688_5 Domain of unknown function (DU1801) - - - 0.0002641 51.0
TLS3_k127_6605973_0 choline dehydrogenase activity K03333 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016614,GO:0016899,GO:0016995,GO:0044419,GO:0051704,GO:0055114 1.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 601.0
TLS3_k127_6605973_1 PFAM SH3 type 3 domain protein - - - 0.000001358 56.0
TLS3_k127_6626743_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 517.0
TLS3_k127_6626743_1 COGs COG4591 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000006899 239.0
TLS3_k127_6626743_2 PFAM secretion protein HlyD family protein K01993 - - 0.00000000000000000000000000000000000000000000000000005544 202.0
TLS3_k127_66337_0 self proteolysis - - - 0.000000000000000001241 98.0
TLS3_k127_66337_1 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000002243 70.0
TLS3_k127_66337_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.0000003267 55.0
TLS3_k127_66337_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.000001389 53.0
TLS3_k127_6684607_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 8.748e-281 886.0
TLS3_k127_6684607_1 PFAM Abortive infection protein K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 315.0
TLS3_k127_6684607_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000001048 229.0
TLS3_k127_6684607_3 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000003012 184.0
TLS3_k127_6684607_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.00000000000000000000000000000000000000000000944 167.0
TLS3_k127_6684607_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000002 143.0
TLS3_k127_6684607_6 - - - - 0.00000000000000000000000000000000159 146.0
TLS3_k127_6684607_7 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.0000000000000000000002112 109.0
TLS3_k127_6684607_8 - - - - 0.0000000000000001496 91.0
TLS3_k127_6684607_9 PFAM DegV family protein - - - 0.0009594 44.0
TLS3_k127_6750784_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000002083 170.0
TLS3_k127_6750784_1 branched-chain amino acid - - - 0.000000000000000000000003741 105.0
TLS3_k127_6750784_2 AzlC protein - - - 0.00000000000000001249 85.0
TLS3_k127_6852358_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 4.396e-197 628.0
TLS3_k127_6852358_1 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 392.0
TLS3_k127_6852358_2 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 308.0
TLS3_k127_6852358_3 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000003079 132.0
TLS3_k127_6852358_4 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.000000000000000000000001901 106.0
TLS3_k127_6852358_5 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000002187 113.0
TLS3_k127_6866423_0 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 514.0
TLS3_k127_6866423_1 SAF K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 492.0
TLS3_k127_6866423_2 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 289.0
TLS3_k127_6866423_3 PFAM NAD-dependent epimerase dehydratase K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003381 283.0
TLS3_k127_6866423_4 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000000000000000001808 221.0
TLS3_k127_6866423_6 Domain of unknown function (DUF4260) - - - 0.0000000000000000000000000000000000003884 143.0
TLS3_k127_6866423_7 lipid-A-disaccharide synthase activity K00748 - 2.4.1.182 0.00000000000000000000000000000003296 127.0
TLS3_k127_6869656_0 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 318.0
TLS3_k127_6869656_1 Domain of unknown function (DUF348) - - - 0.00000000000000000000000000000000000000000000000000000000007435 216.0
TLS3_k127_6869656_2 Cell envelope-like function transcriptional attenuator common domain protein - - - 0.000000000000000000002509 107.0
TLS3_k127_6880628_0 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 467.0
TLS3_k127_6880628_1 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 401.0
TLS3_k127_6880628_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000008163 218.0
TLS3_k127_6880628_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000003011 176.0
TLS3_k127_6880628_4 Protein of unknown function DUF72 - - - 0.00000000000000000000007344 101.0
TLS3_k127_6880628_5 Ribosomal protein S1 K02945 - - 0.0000001698 57.0
TLS3_k127_6883614_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 507.0
TLS3_k127_6883614_1 PFAM PSP1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 347.0
TLS3_k127_6883614_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00338,K03615 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000006649 250.0
TLS3_k127_6883614_3 - - - - 0.000000000000000000000000000000000000004928 154.0
TLS3_k127_6883614_4 Histidine phosphatase superfamily (branch 1) K01834 - 5.4.2.11 0.0000000000000000000000000000000001024 142.0
TLS3_k127_6885483_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 2.03e-247 772.0
TLS3_k127_6885483_1 acetyl-CoA carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 584.0
TLS3_k127_6885483_10 CoA carboxylase activity K01965,K02160 - 6.4.1.3 0.000000000000000000000000003919 116.0
TLS3_k127_6885483_11 F420H(2)-dependent quinone reductase - - - 0.00000000000000008157 86.0
TLS3_k127_6885483_12 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.0000000002084 61.0
TLS3_k127_6885483_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 439.0
TLS3_k127_6885483_3 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 353.0
TLS3_k127_6885483_4 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001463 272.0
TLS3_k127_6885483_5 PFAM glutamine amidotransferase class-I K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000369 239.0
TLS3_k127_6885483_6 CYTH domain K05873 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000005984 190.0
TLS3_k127_6885483_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000001252 191.0
TLS3_k127_6885483_8 Acetyltransferase, gnat family - - - 0.000000000000000000000000000000000000000001696 161.0
TLS3_k127_6885483_9 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000002824 149.0
TLS3_k127_6890384_0 Magnesium chelatase, subunit ChlI K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 402.0
TLS3_k127_6890384_1 Ribosomal protein S1 K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 338.0
TLS3_k127_6890384_2 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 295.0
TLS3_k127_6890384_4 - - - - 0.000000000000000000000000000000000000000000000000008189 184.0
TLS3_k127_6912505_0 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005929 604.0
TLS3_k127_6912505_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 539.0
TLS3_k127_6912505_10 queuine tRNA-ribosyltransferase activity - - - 0.0000000000000000000000000000000000000000000002004 171.0
TLS3_k127_6912505_11 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000001486 166.0
TLS3_k127_6912505_12 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.000000000000000000000000000000000000000007052 160.0
TLS3_k127_6912505_13 GNAT acetyltransferase - - - 0.0000000000000000000000000000000001236 143.0
TLS3_k127_6912505_14 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000000007645 129.0
TLS3_k127_6912505_15 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000002814 107.0
TLS3_k127_6912505_2 Uncharacterised ACR (DUF711) K09157 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 363.0
TLS3_k127_6912505_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 339.0
TLS3_k127_6912505_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000148 270.0
TLS3_k127_6912505_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005778 263.0
TLS3_k127_6912505_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001989 247.0
TLS3_k127_6912505_7 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000005907 228.0
TLS3_k127_6912505_8 regulatory protein, arsR - - - 0.0000000000000000000000000000000000000000000000000000003038 198.0
TLS3_k127_6912505_9 PFAM Appr-1-p processing domain protein - - - 0.0000000000000000000000000000000000000000000001181 174.0
TLS3_k127_6922572_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000004163 207.0
TLS3_k127_6922572_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000008618 187.0
TLS3_k127_6923279_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 7.861e-262 815.0
TLS3_k127_6923279_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 454.0
TLS3_k127_6925816_0 PFAM ABC transporter related K09972 - - 0.00000000000000000000000000000000000000000000000000000000000000000003244 233.0
TLS3_k127_6925816_1 Thioesterase superfamily - - - 0.00000000000000000007047 94.0
TLS3_k127_6972042_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 4.91e-297 921.0
TLS3_k127_6972042_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 461.0
TLS3_k127_6972042_2 PFAM UbiA prenyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 388.0
TLS3_k127_6972042_3 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 325.0
TLS3_k127_6972042_4 TIGRFAM mevalonate kinase K00869 - 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001165 285.0
TLS3_k127_6972042_5 - - - - 0.0000000000000000000000000000000000000000000000006057 184.0
TLS3_k127_6972042_6 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000008711 136.0
TLS3_k127_6972042_7 Allophanate hydrolase subunit 1 K06351 - - 0.000000000000000000000000000000004713 134.0
TLS3_k127_6972042_8 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000003452 119.0
TLS3_k127_69748_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 3.106e-226 709.0
TLS3_k127_69748_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 561.0
TLS3_k127_69748_10 sequence-specific DNA binding K03718,K03719 - - 0.000000000000000000000000000000000000000007262 158.0
TLS3_k127_69748_2 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00821,K05830,K09251 - 2.6.1.11,2.6.1.17,2.6.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 534.0
TLS3_k127_69748_3 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 527.0
TLS3_k127_69748_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 453.0
TLS3_k127_69748_5 Bacterial extracellular solute-binding protein K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009696 358.0
TLS3_k127_69748_6 PFAM binding-protein-dependent transport systems inner membrane component K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 307.0
TLS3_k127_69748_7 Binding-protein-dependent transport system inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 301.0
TLS3_k127_69748_8 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K14387 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000357 293.0
TLS3_k127_69748_9 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K14387 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006774 264.0
TLS3_k127_6999934_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 383.0
TLS3_k127_6999934_1 PFAM metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000625 189.0
TLS3_k127_7011120_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 386.0
TLS3_k127_7011120_1 NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000002592 146.0
TLS3_k127_7038569_0 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 4.279e-277 863.0
TLS3_k127_7038569_1 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 524.0
TLS3_k127_7038569_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 385.0
TLS3_k127_7038569_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003194 251.0
TLS3_k127_7038569_4 - - - - 0.0000000000000000006564 100.0
TLS3_k127_7038569_5 - - - - 0.0000000000000006406 80.0
TLS3_k127_7038569_6 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000001544 88.0
TLS3_k127_7038569_7 - - - - 0.00002868 47.0
TLS3_k127_7050008_0 Heparinase II/III N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008202 495.0
TLS3_k127_7050008_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 325.0
TLS3_k127_7072369_0 Beta-eliminating lyase K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 397.0
TLS3_k127_7072369_1 Polysaccharide biosynthesis protein K01710,K01784,K13318,K13322,K16439,K19857 - 4.2.1.46,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 395.0
TLS3_k127_7072369_2 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 296.0
TLS3_k127_7072369_3 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001305 277.0
TLS3_k127_7072369_4 Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000000000000005012 191.0
TLS3_k127_7080097_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1542.0
TLS3_k127_7080097_1 Transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 445.0
TLS3_k127_7082968_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.097e-257 811.0
TLS3_k127_7082968_1 TIGRFAM phosphate binding protein - - - 1.159e-228 727.0
TLS3_k127_7082968_10 Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities K01524 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006797,GO:0006798,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008894,GO:0009056,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034641,GO:0042594,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:1901360,GO:1901575 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 359.0
TLS3_k127_7082968_11 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 345.0
TLS3_k127_7082968_12 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 322.0
TLS3_k127_7082968_13 Two component transcriptional regulator, winged helix family K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003569 256.0
TLS3_k127_7082968_14 isochorismatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001966 252.0
TLS3_k127_7082968_15 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002317 262.0
TLS3_k127_7082968_16 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001598 251.0
TLS3_k127_7082968_17 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000003371 198.0
TLS3_k127_7082968_18 low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000005926 154.0
TLS3_k127_7082968_19 Phosphoglycerate mutase family K08296 - - 0.0000000000000000000000000004768 121.0
TLS3_k127_7082968_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 1.33e-225 705.0
TLS3_k127_7082968_20 CHAD domain - - - 0.00000000000000000006877 100.0
TLS3_k127_7082968_3 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 509.0
TLS3_k127_7082968_4 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 419.0
TLS3_k127_7082968_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 407.0
TLS3_k127_7082968_6 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 399.0
TLS3_k127_7082968_7 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 387.0
TLS3_k127_7082968_8 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 370.0
TLS3_k127_7082968_9 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 366.0
TLS3_k127_7092423_0 PFAM fumarate lyase K01679 - 4.2.1.2 1.422e-202 641.0
TLS3_k127_7092423_1 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 567.0
TLS3_k127_7092423_10 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004331 287.0
TLS3_k127_7092423_12 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.00000000000000000000000000000000000000000000000000000001176 208.0
TLS3_k127_7092423_13 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000766 198.0
TLS3_k127_7092423_14 phosphorelay sensor kinase activity K16923 - - 0.000000000000000000000000000000000000000000000000002008 190.0
TLS3_k127_7092423_15 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.000000000000000000000000000000000000000411 156.0
TLS3_k127_7092423_16 Cobalt transport protein K16785 - - 0.0000000000000000000000000000000000000009014 157.0
TLS3_k127_7092423_17 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000000000000000000000001883 147.0
TLS3_k127_7092423_18 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000008151 145.0
TLS3_k127_7092423_19 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000000000000004672 91.0
TLS3_k127_7092423_2 PFAM Shikimate quinate 5-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 361.0
TLS3_k127_7092423_3 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 354.0
TLS3_k127_7092423_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 324.0
TLS3_k127_7092423_5 ATPase activity K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 323.0
TLS3_k127_7092423_6 PFAM Inosine uridine-preferring nucleoside hydrolase K01239 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 319.0
TLS3_k127_7092423_7 PFAM Inosine uridine-preferring nucleoside hydrolase K01239 - 3.2.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 297.0
TLS3_k127_7092423_8 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009983 293.0
TLS3_k127_7092423_9 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000102 283.0
TLS3_k127_7133991_0 adenosylmethionine-8-amino-7-oxononanoate transaminase activity K15372 - 2.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 554.0
TLS3_k127_7133991_1 - - - - 0.0000000000001182 74.0
TLS3_k127_7133991_2 Yip1 domain - - - 0.0000000000006429 78.0
TLS3_k127_7147210_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 408.0
TLS3_k127_7147210_1 - K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008801 415.0
TLS3_k127_7147210_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005815 383.0
TLS3_k127_7147210_3 - K01992 - - 0.00000000000000000000000000000000000000000000000000000001017 206.0
TLS3_k127_7147210_4 Threonyl alanyl tRNA synthetase SAD K07050 - - 0.00000000000000000000000000000216 123.0
TLS3_k127_7147210_5 Domain of unknown function (DUF4340) - - - 0.00000000000005641 81.0
TLS3_k127_7174657_0 aminotransferase class I and II K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 490.0
TLS3_k127_7174657_1 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 355.0
TLS3_k127_7174657_2 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000005408 244.0
TLS3_k127_7174657_3 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000003545 114.0
TLS3_k127_7174657_4 Belongs to the Nudix hydrolase family - - - 0.00000003237 58.0
TLS3_k127_7174657_5 helix_turn_helix, Lux Regulon K11624 - - 0.00000003669 55.0
TLS3_k127_718130_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 334.0
TLS3_k127_718130_1 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000001073 262.0
TLS3_k127_718130_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006077 248.0
TLS3_k127_718130_3 aminoglycoside 3-N-acetyltransferase activity K00662 - 2.3.1.81 0.0000000000000000000000000000000000000000000000000000000003101 211.0
TLS3_k127_718130_4 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000001983 143.0
TLS3_k127_7217425_0 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 402.0
TLS3_k127_7217425_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 391.0
TLS3_k127_7217425_2 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.00001218 54.0
TLS3_k127_7218721_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 612.0
TLS3_k127_7218721_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 537.0
TLS3_k127_7218721_10 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000001337 208.0
TLS3_k127_7218721_11 PFAM NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000002675 170.0
TLS3_k127_7218721_13 domain, Protein - - - 0.000000000000000000000002206 115.0
TLS3_k127_7218721_14 RHS Repeat - - - 0.0000000000000000001095 96.0
TLS3_k127_7218721_15 Ami_3 K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.0005313 51.0
TLS3_k127_7218721_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 406.0
TLS3_k127_7218721_3 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 406.0
TLS3_k127_7218721_4 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 342.0
TLS3_k127_7218721_5 PFAM secretion protein HlyD family protein K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 347.0
TLS3_k127_7218721_6 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 336.0
TLS3_k127_7218721_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 318.0
TLS3_k127_7218721_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001072 275.0
TLS3_k127_7218721_9 Putative FMN-binding domain K07734 - - 0.000000000000000000000000000000000000000000000000000000001628 206.0
TLS3_k127_727935_0 Acyl transferase domain in polyketide synthase (PKS) enzymes. - - - 0.0 1753.0
TLS3_k127_727935_1 Inner membrane component of T3SS, cytoplasmic domain - - - 4.314e-222 726.0
TLS3_k127_727935_2 serine threonine protein kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000003166 261.0
TLS3_k127_7289_0 Tetratricopeptide repeat - - - 2.088e-218 703.0
TLS3_k127_7289_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 325.0
TLS3_k127_7289_10 - - - - 0.000000000000000000000000000000000000005337 156.0
TLS3_k127_7289_11 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000001818 149.0
TLS3_k127_7289_12 Phosphoglycerate kinase K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000000000000000005948 119.0
TLS3_k127_7289_14 - - - - 0.00000000000000000001205 95.0
TLS3_k127_7289_15 PFAM peptidase U32 K08303 - - 0.00000000000000001301 85.0
TLS3_k127_7289_16 Methionine biosynthesis protein MetW K18827 - 2.1.1.294,2.7.1.181 0.00000000000002539 83.0
TLS3_k127_7289_17 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.00006316 52.0
TLS3_k127_7289_18 Peptidase_C39 like family - - - 0.000655 52.0
TLS3_k127_7289_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 317.0
TLS3_k127_7289_3 WD domain, G-beta repeat K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 335.0
TLS3_k127_7289_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000643 286.0
TLS3_k127_7289_5 alpha, beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000001429 241.0
TLS3_k127_7289_6 - - - - 0.00000000000000000000000000000000000000000000000000000000003458 214.0
TLS3_k127_7289_7 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000005583 210.0
TLS3_k127_7289_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000001445 211.0
TLS3_k127_7289_9 - - - - 0.0000000000000000000000000000000000000000000000006476 179.0
TLS3_k127_7314986_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733,K22010 - 4.2.3.1 1.89e-211 670.0
TLS3_k127_7314986_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 433.0
TLS3_k127_7314986_10 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00004517 49.0
TLS3_k127_7314986_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 352.0
TLS3_k127_7314986_3 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000108 278.0
TLS3_k127_7314986_4 protein histidine kinase activity K01768,K11527,K18143 - 2.7.13.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000005912 284.0
TLS3_k127_7314986_5 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002159 261.0
TLS3_k127_7314986_6 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000005749 248.0
TLS3_k127_7314986_7 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000005462 212.0
TLS3_k127_7314986_8 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000003429 206.0
TLS3_k127_7314986_9 PFAM response regulator receiver K11443 - - 0.00000000000000000000000000000000000000001155 156.0
TLS3_k127_7318773_0 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000003774 179.0
TLS3_k127_7318773_1 spore germination - - - 0.0000000000000000000000000000000000000001486 157.0
TLS3_k127_7318773_2 LysM domain K07273,K22278 - 3.5.1.104 0.0000000000000000000000222 105.0
TLS3_k127_7388522_0 N-4 methylation of cytosine K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 471.0
TLS3_k127_7388522_1 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 344.0
TLS3_k127_7388522_10 PFAM metallophosphoesterase - - - 0.000000000000000000000000005599 113.0
TLS3_k127_7388522_11 Protein of unknown function (DUF3467) - - - 0.000000000000000000101 92.0
TLS3_k127_7388522_12 SCP-like extracellular protein. Source PGD - - - 0.000000000000000003346 96.0
TLS3_k127_7388522_13 Ig-like domain from next to BRCA1 gene - - - 0.0000000000003174 81.0
TLS3_k127_7388522_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 340.0
TLS3_k127_7388522_3 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 326.0
TLS3_k127_7388522_4 PFAM Translin K07477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004199 248.0
TLS3_k127_7388522_5 Domain of unknown function (DUF4349) - - - 0.00000000000000000000000000000000000000000000000000000001969 209.0
TLS3_k127_7388522_6 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000001777 183.0
TLS3_k127_7388522_7 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000003371 161.0
TLS3_k127_7388522_8 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000000000000001321 167.0
TLS3_k127_7388522_9 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000002599 152.0
TLS3_k127_7470050_0 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000001034 191.0
TLS3_k127_7470050_1 LysM domain - - - 0.000000000000000000000000000000000000000000001186 175.0
TLS3_k127_7470050_2 SMART PDZ DHR GLGF domain protein K11749 - - 0.0000000000000000000000000000000000000000001289 174.0
TLS3_k127_7470050_3 Hit family K02503 - - 0.00000000000000000000000000000001059 131.0
TLS3_k127_7470050_4 zinc metalloprotease K11749 - - 0.0003908 52.0
TLS3_k127_7536762_0 Belongs to the peptidase S8 family - - - 0.0 1146.0
TLS3_k127_7536762_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 537.0
TLS3_k127_7536762_2 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 361.0
TLS3_k127_7536762_3 ROK family K00886 - 2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 308.0
TLS3_k127_7536762_4 Citrate lyase subunit beta-like protein K11390 GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0008150,GO:0009987,GO:0016043,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0019222,GO:0022607,GO:0030656,GO:0031323,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0046872,GO:0046912,GO:0047777,GO:0050789,GO:0050794,GO:0051171,GO:0051193,GO:0051259,GO:0051260,GO:0062012,GO:0065003,GO:0065007,GO:0070206,GO:0070207,GO:0071840,GO:0106064,GO:1901401 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006196 265.0
TLS3_k127_7536762_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000001638 228.0
TLS3_k127_7536762_6 SMART regulatory protein, ArsR - - - 0.000000000000008896 83.0
TLS3_k127_7591422_0 PFAM SMC domain protein K03546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 602.0
TLS3_k127_7591422_1 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 427.0
TLS3_k127_7591422_2 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 382.0
TLS3_k127_7591422_3 PFAM Glycosyl transferase family 2 K14597 - - 0.0000000000000000000000000000000000000000000000000000000000000000007847 241.0
TLS3_k127_7591422_4 Belongs to the peptidase S51 family - - - 0.000000000000000000000000000000000000007722 154.0
TLS3_k127_7591422_5 peptidase M42 family protein - - - 0.00000000000000000000000000006383 118.0
TLS3_k127_7627943_0 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 414.0
TLS3_k127_7627943_1 cellular response to dsDNA K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000666 214.0
TLS3_k127_7627943_2 DNA-binding protein - - - 0.000000000000000000001492 98.0
TLS3_k127_7627943_3 protein, putative amidase K01470 - 3.5.2.10 0.00000000000000002521 89.0
TLS3_k127_7749166_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 495.0
TLS3_k127_7749166_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 458.0
TLS3_k127_7749166_4 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000003887 243.0
TLS3_k127_7749166_5 oligosaccharyl transferase activity - - - 0.000000001955 70.0
TLS3_k127_7749166_6 Psort location Cytoplasmic, score 8.96 - - - 0.000004739 52.0
TLS3_k127_7749166_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00003694 57.0
TLS3_k127_7753976_0 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000003171 256.0
TLS3_k127_7753976_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03793 - 1.5.1.33 0.00000000000000000000000000000000002975 141.0
TLS3_k127_7753976_2 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K07589 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8 0.00000000000000000000000001879 112.0
TLS3_k127_7753976_3 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity K00950,K13940 - 2.7.6.3,4.1.2.25 0.000000000000000000000006601 109.0
TLS3_k127_7753976_4 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000001716 80.0
TLS3_k127_7768753_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1104.0
TLS3_k127_7768753_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 9.746e-298 923.0
TLS3_k127_7768753_10 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000005422 208.0
TLS3_k127_7768753_11 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000006653 196.0
TLS3_k127_7768753_12 - - - - 0.0000000000000000000000000000000000000000008043 160.0
TLS3_k127_7768753_13 GCN5 family acetyltransferase K22477 - 2.3.1.1 0.000000000000000000000000001852 117.0
TLS3_k127_7768753_14 DegT/DnrJ/EryC1/StrS aminotransferase family K04487 - 2.8.1.7 0.00000000000000000000000002052 117.0
TLS3_k127_7768753_15 Belongs to the small heat shock protein (HSP20) family - - - 0.00000000000000000000000008114 111.0
TLS3_k127_7768753_16 response regulator K03413,K07719 - - 0.0000000000000000000000007571 109.0
TLS3_k127_7768753_17 PFAM TadE family protein K12287 - - 0.000000000000000000825 100.0
TLS3_k127_7768753_18 Cytochrome c - - - 0.000000000000243 78.0
TLS3_k127_7768753_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 4.624e-257 803.0
TLS3_k127_7768753_20 Transcriptional regulator - - - 0.0000000009194 67.0
TLS3_k127_7768753_21 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000002272 64.0
TLS3_k127_7768753_22 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 0.00001031 58.0
TLS3_k127_7768753_23 Iron-sulphur cluster assembly - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.0002127 46.0
TLS3_k127_7768753_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 500.0
TLS3_k127_7768753_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 496.0
TLS3_k127_7768753_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 317.0
TLS3_k127_7768753_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 311.0
TLS3_k127_7768753_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00338,K03615 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001584 278.0
TLS3_k127_7768753_8 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000004177 236.0
TLS3_k127_7768753_9 histidine kinase HAMP region domain protein K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000001515 228.0
TLS3_k127_7771863_0 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.0 1025.0
TLS3_k127_7771863_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 6.221e-302 941.0
TLS3_k127_7771863_10 response regulator K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 293.0
TLS3_k127_7771863_11 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001151 246.0
TLS3_k127_7771863_12 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000002609 245.0
TLS3_k127_7771863_13 COG0569 K transport systems, NAD-binding component K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000002117 228.0
TLS3_k127_7771863_14 - - - - 0.000000000000000000000000000000000000000000001405 171.0
TLS3_k127_7771863_15 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000007473 162.0
TLS3_k127_7771863_16 PhoQ Sensor - - - 0.000000000000000000000000000000000000000132 157.0
TLS3_k127_7771863_17 Methyltransferase domain - - - 0.0000000000000000000000000000000000000615 152.0
TLS3_k127_7771863_18 - - - - 0.0000000000000000000000000000000000004821 148.0
TLS3_k127_7771863_19 ASCH - - - 0.00000000000000000000000000000000004646 147.0
TLS3_k127_7771863_2 Histidine kinase K07646 - 2.7.13.3 5.297e-289 914.0
TLS3_k127_7771863_20 - - - - 0.00000000000000000007068 98.0
TLS3_k127_7771863_21 - - - - 0.000000000000000001471 90.0
TLS3_k127_7771863_22 - - - - 0.0000000001066 73.0
TLS3_k127_7771863_23 SnoaL-like domain - - - 0.0000000004651 63.0
TLS3_k127_7771863_24 Helix-turn-helix of DDE superfamily endonuclease - - - 0.00002493 50.0
TLS3_k127_7771863_3 Amino acid permease - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 1.56e-266 835.0
TLS3_k127_7771863_4 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 2.112e-260 815.0
TLS3_k127_7771863_5 helix_turn_helix, Lux Regulon K03556 - - 3.219e-227 734.0
TLS3_k127_7771863_6 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 - 2.4.1.321 6.798e-195 618.0
TLS3_k127_7771863_7 H( )-transporting two-sector ATPase K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 497.0
TLS3_k127_7771863_8 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 447.0
TLS3_k127_7771863_9 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 381.0
TLS3_k127_7826963_0 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006965 569.0
TLS3_k127_7826963_1 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 554.0
TLS3_k127_7826963_10 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000000000000000000000000000000000001055 216.0
TLS3_k127_7826963_11 PFAM Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000005887 195.0
TLS3_k127_7826963_12 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) K07173 - 4.4.1.21 0.00000000000000000000000000000000000000000000000009611 186.0
TLS3_k127_7826963_13 Acyl-transferase - - - 0.0000000000000000000000000000000001357 147.0
TLS3_k127_7826963_14 Domain of unknown function (DUF4342) - - - 0.000000000000000000004107 94.0
TLS3_k127_7826963_15 Clostripain family - - - 0.000001749 55.0
TLS3_k127_7826963_2 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 488.0
TLS3_k127_7826963_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K19969 - 4.2.3.152 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 474.0
TLS3_k127_7826963_4 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 434.0
TLS3_k127_7826963_5 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 341.0
TLS3_k127_7826963_6 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 293.0
TLS3_k127_7826963_7 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003248 264.0
TLS3_k127_7826963_8 Threonyl alanyl tRNA synthetase SAD K07050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001375 254.0
TLS3_k127_7826963_9 PFAM ThiJ PfpI domain protein K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000004252 252.0
TLS3_k127_7841306_0 Endoribonuclease that initiates mRNA decay K18682 - - 3.001e-209 661.0
TLS3_k127_7841306_1 ABC transporter substrate-binding protein PnrA-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 301.0
TLS3_k127_7841306_2 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000000003095 188.0
TLS3_k127_7841306_3 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000002731 192.0
TLS3_k127_7841306_4 protein histidine kinase activity K01768,K11527,K18143 - 2.7.13.3,4.6.1.1 0.000000000000000000000000000000000000000000001562 186.0
TLS3_k127_7841306_5 response regulator, receiver K11527 - 2.7.13.3 0.000000000000000000000000000000000000000000573 178.0
TLS3_k127_7841306_6 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000000003516 158.0
TLS3_k127_7841306_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000171 81.0
TLS3_k127_7841306_8 Methyltransferase type 12 - - - 0.000000000008718 71.0
TLS3_k127_7841306_9 Diguanylate cyclase - - - 0.00002656 57.0
TLS3_k127_7841888_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 4.973e-237 748.0
TLS3_k127_7841888_1 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 1.357e-200 642.0
TLS3_k127_7841888_10 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000002081 180.0
TLS3_k127_7841888_11 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1901576 - 0.00000000000000000000000000000000009536 136.0
TLS3_k127_7841888_12 - - - - 0.0000000000000000000000000000000002757 142.0
TLS3_k127_7841888_13 Cyclic-di-AMP receptor - - - 0.000000000000000000000000000004547 125.0
TLS3_k127_7841888_14 - - - - 0.0000000000000000000002882 101.0
TLS3_k127_7841888_15 Cyclic-di-AMP receptor - - - 0.00000000000000003176 85.0
TLS3_k127_7841888_16 - - - - 0.00000000000003796 75.0
TLS3_k127_7841888_18 Tricorn protease homolog K08676 - - 0.00009572 54.0
TLS3_k127_7841888_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 581.0
TLS3_k127_7841888_3 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 498.0
TLS3_k127_7841888_4 transferase activity, transferring glycosyl groups K21369 - 2.4.1.270 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 465.0
TLS3_k127_7841888_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 452.0
TLS3_k127_7841888_6 Sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008973 381.0
TLS3_k127_7841888_7 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 314.0
TLS3_k127_7841888_8 pseudouridine synthase activity K06178,K06181,K06183 - 5.4.99.19,5.4.99.20,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000002778 238.0
TLS3_k127_7841888_9 - - - - 0.0000000000000000000000000000000000000000000000000000008179 201.0
TLS3_k127_7878441_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.348e-276 868.0
TLS3_k127_7878441_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 5.123e-210 681.0
TLS3_k127_7878441_10 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 308.0
TLS3_k127_7878441_11 PFAM adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007436 298.0
TLS3_k127_7878441_12 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000009535 199.0
TLS3_k127_7878441_13 geranylgeranyl reductase activity - - - 0.0000000000000000000000000000000000000000000000008699 190.0
TLS3_k127_7878441_14 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000000000000000000004654 171.0
TLS3_k127_7878441_15 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000008074 160.0
TLS3_k127_7878441_16 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000149 152.0
TLS3_k127_7878441_17 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.0000009071 61.0
TLS3_k127_7878441_2 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 545.0
TLS3_k127_7878441_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006533 514.0
TLS3_k127_7878441_4 Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 520.0
TLS3_k127_7878441_5 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 504.0
TLS3_k127_7878441_6 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009075 492.0
TLS3_k127_7878441_7 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 475.0
TLS3_k127_7878441_8 nitrogen compound transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 477.0
TLS3_k127_7878441_9 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009035 437.0
TLS3_k127_7897361_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 7.601e-208 660.0
TLS3_k127_7897361_1 PFAM Aminotransferase class I and II K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 596.0
TLS3_k127_7897361_10 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000003423 119.0
TLS3_k127_7897361_12 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.000000000000003318 87.0
TLS3_k127_7897361_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006759 469.0
TLS3_k127_7897361_3 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 465.0
TLS3_k127_7897361_4 SMART Nucleotide binding protein, PINc - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 456.0
TLS3_k127_7897361_5 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 331.0
TLS3_k127_7897361_6 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000003623 189.0
TLS3_k127_7897361_7 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000005868 157.0
TLS3_k127_7897361_8 NUDIX domain K12944 - - 0.000000000000000000000000000000000000000008273 158.0
TLS3_k127_7897361_9 EamA-like transporter family - - - 0.00000000000000000000000000000000005523 144.0
TLS3_k127_7898799_0 3-deoxy-manno-octulosonate-8-phosphatase activity K00983,K03270 - 2.7.7.43,3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 489.0
TLS3_k127_7898799_1 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 462.0
TLS3_k127_7898799_2 NeuB family K01654 - 2.5.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 441.0
TLS3_k127_7898799_3 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 363.0
TLS3_k127_7898799_4 UDP-N-acetylglucosamine 2-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001264 222.0
TLS3_k127_7898799_5 Sulfotransferase domain - - - 0.00000000000000000000000000000000005523 144.0
TLS3_k127_7898799_6 - - - - 0.0000000000003688 82.0
TLS3_k127_7915052_0 DEAD DEAH box helicase domain protein K06877 - - 5.772e-299 939.0
TLS3_k127_7915052_1 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 8.372e-287 890.0
TLS3_k127_7915052_10 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000002804 139.0
TLS3_k127_7915052_11 PFAM Rieske 2Fe-2S domain K03886 - - 0.0000000000000000000001124 105.0
TLS3_k127_7915052_12 COG1290 Cytochrome b subunit of the bc complex K03888 - - 0.00000000000000007499 95.0
TLS3_k127_7915052_13 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.000000002726 63.0
TLS3_k127_7915052_14 Cytochrome c K00406,K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000002578 64.0
TLS3_k127_7915052_15 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.000488 48.0
TLS3_k127_7915052_16 PFAM restriction endonuclease K07448 - - 0.0006831 50.0
TLS3_k127_7915052_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 542.0
TLS3_k127_7915052_3 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 440.0
TLS3_k127_7915052_4 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 344.0
TLS3_k127_7915052_5 phosphate ion binding K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008512 277.0
TLS3_k127_7915052_6 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000004701 254.0
TLS3_k127_7915052_7 lysyltransferase activity K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000389 252.0
TLS3_k127_7915052_8 Cytochrome b/b6/petB K00412,K03888 - - 0.0000000000000000000000000000000000000000000000000000000000000000001832 235.0
TLS3_k127_7915052_9 2 iron, 2 sulfur cluster binding K13643 - - 0.000000000000000000000000000000000000000000000000000006622 194.0
TLS3_k127_7922491_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 3.573e-201 640.0
TLS3_k127_7922491_1 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 372.0
TLS3_k127_7922491_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 330.0
TLS3_k127_7922491_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004227 278.0
TLS3_k127_7922491_4 TIGRFAM DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000001826 255.0
TLS3_k127_7922491_5 - - - - 0.00000000000000000000000000000000000000000000000000000008039 214.0
TLS3_k127_7922491_6 CoA binding domain K06929 - - 0.00000000000000000000000000000000002231 154.0
TLS3_k127_7922491_7 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K07443 - - 0.0000000000000000000000207 106.0
TLS3_k127_7922491_8 - - - - 0.00002021 52.0
TLS3_k127_7924773_0 PFAM NHL repeat containing protein - - - 0.0 1045.0
TLS3_k127_7924773_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 575.0
TLS3_k127_7924773_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 479.0
TLS3_k127_7924773_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 439.0
TLS3_k127_7924773_4 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000002625 229.0
TLS3_k127_7924773_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000001706 101.0
TLS3_k127_7924773_6 Macrocin-O-methyltransferase (TylF) - - - 0.000000000000000000003332 94.0
TLS3_k127_7961037_0 Cytochrome b/b6/petB - - - 0.0 1175.0
TLS3_k127_7961037_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 1.997e-231 724.0
TLS3_k127_7961037_2 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 579.0
TLS3_k127_7961037_3 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 296.0
TLS3_k127_7961037_4 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001282 233.0
TLS3_k127_7961037_5 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000007558 116.0
TLS3_k127_8001945_0 PFAM amidohydrolase K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 521.0
TLS3_k127_8001945_1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01476,K01480 GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 3.5.3.1,3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 372.0
TLS3_k127_8001945_10 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000006082 74.0
TLS3_k127_8001945_13 PFAM Flp Fap pilin component K02651 - - 0.00001321 49.0
TLS3_k127_8001945_2 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 312.0
TLS3_k127_8001945_3 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000005726 243.0
TLS3_k127_8001945_4 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000001157 241.0
TLS3_k127_8001945_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000368 237.0
TLS3_k127_8001945_6 Peptidyl-prolyl cis-trans isomerase K01802,K03767,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000004608 159.0
TLS3_k127_8001945_7 - - - - 0.000000000000000000000000000000000001686 148.0
TLS3_k127_8001945_8 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000008115 134.0
TLS3_k127_8022743_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 592.0
TLS3_k127_8022743_1 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 414.0
TLS3_k127_8022743_2 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 391.0
TLS3_k127_8022743_3 Two component transcriptional regulator, winged helix family K07669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 364.0
TLS3_k127_8022743_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218,K05926 - 2.1.1.185,2.1.1.230 0.000000000000000000000000000000000000000000000000000000000000000000000000005928 261.0
TLS3_k127_8022743_5 Pseudouridine synthase K06177,K06179,K06180 - 5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000001641 201.0
TLS3_k127_8022743_7 Transglycosylase SLT domain - - - 0.000000000002306 76.0
TLS3_k127_8053147_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1120.0
TLS3_k127_8053147_1 PFAM metal-dependent phosphohydrolase, HD sub domain K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006414 576.0
TLS3_k127_8053147_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009858 503.0
TLS3_k127_8053147_3 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 429.0
TLS3_k127_8053147_4 Nucleotidyl transferase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 391.0
TLS3_k127_8053147_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000368 237.0
TLS3_k127_8053147_6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000003777 195.0
TLS3_k127_8053147_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000005007 185.0
TLS3_k127_8053147_8 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000005569 134.0
TLS3_k127_8053147_9 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000001341 101.0
TLS3_k127_8104017_0 PFAM UDP-glucose GDP-mannose dehydrogenase K13015 - 1.1.1.136 3.425e-207 652.0
TLS3_k127_8104017_1 Short-chain dehydrogenase reductase SDR K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 434.0
TLS3_k127_8104017_10 helix_turn_helix, arabinose operon control protein K21701 - - 0.000000000000000000000000000000000000000002729 158.0
TLS3_k127_8104017_11 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000001081 152.0
TLS3_k127_8104017_12 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000001831 144.0
TLS3_k127_8104017_13 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000000000000000000001216 134.0
TLS3_k127_8104017_14 Bacterial protein of unknown function (DUF951) - - - 0.0000000000000000001303 92.0
TLS3_k127_8104017_15 aminopeptidase activity K01179,K01269 - 3.2.1.4 0.0009687 42.0
TLS3_k127_8104017_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 311.0
TLS3_k127_8104017_3 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002452 272.0
TLS3_k127_8104017_4 polysaccharide biosynthetic process K16694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001601 274.0
TLS3_k127_8104017_5 PFAM peptidase M22 glycoprotease K14742 - - 0.000000000000000000000000000000000000000000000000000000000000000005876 232.0
TLS3_k127_8104017_6 Crp-like helix-turn-helix domain K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000001388 231.0
TLS3_k127_8104017_7 PFAM Glycosyl transferases group 1 K19002 - 2.4.1.337 0.0000000000000000000000000000000000000000000000000000000001254 220.0
TLS3_k127_8104017_8 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000000000000000000000007547 206.0
TLS3_k127_8104017_9 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000193 187.0
TLS3_k127_8173657_0 MFS/sugar transport protein K03292 - - 1.839e-207 652.0
TLS3_k127_8173657_1 PFAM aminotransferase class V K01634 - 4.1.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 597.0
TLS3_k127_8173657_10 serine threonine protein kinase - - - 0.000000000006841 75.0
TLS3_k127_8173657_11 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000002246 68.0
TLS3_k127_8173657_2 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 435.0
TLS3_k127_8173657_3 C4-dicarboxylate anaerobic carrier - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 415.0
TLS3_k127_8173657_4 iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 317.0
TLS3_k127_8173657_5 Protein of unknown function (DUF2817) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001178 273.0
TLS3_k127_8173657_6 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000508 199.0
TLS3_k127_8173657_7 succinate dehydrogenase K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000001845 179.0
TLS3_k127_8173657_8 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000000001101 120.0
TLS3_k127_8173657_9 metal-dependent membrane protease K07052 - - 0.0000000000000000000000007029 113.0
TLS3_k127_8186481_0 PFAM Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 611.0
TLS3_k127_8186481_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 573.0
TLS3_k127_8186481_10 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000004265 231.0
TLS3_k127_8186481_11 Putative zincin peptidase - - - 0.00000000000000000000000000000000000000000000000000000000001561 211.0
TLS3_k127_8186481_13 - - - - 0.0000000000000000000000000000005818 125.0
TLS3_k127_8186481_14 - - - - 0.000000000000001895 78.0
TLS3_k127_8186481_2 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 577.0
TLS3_k127_8186481_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 536.0
TLS3_k127_8186481_4 WD40 domain protein beta Propeller K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 516.0
TLS3_k127_8186481_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 438.0
TLS3_k127_8186481_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000643 413.0
TLS3_k127_8186481_7 ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 415.0
TLS3_k127_8186481_8 heme binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 363.0
TLS3_k127_8186481_9 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 311.0
TLS3_k127_8238232_0 PFAM regulatory protein, ArsR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006586 274.0
TLS3_k127_8238232_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000003591 226.0
TLS3_k127_8238232_2 YbaK prolyl-tRNA synthetase associated - - - 0.000000000000000000000000000000000000000000000000000000002861 203.0
TLS3_k127_8238232_3 Integral membrane protein (intg_mem_TP0381) - - - 0.000000000000000000000000000000000000000000000000000003368 199.0
TLS3_k127_8238232_4 NUDIX domain - - - 0.000000000000000000000000000000000000000000000009475 176.0
TLS3_k127_8238232_5 Belongs to the Pirin family K06911 - - 0.000000000000000000000000000000000000000000001251 169.0
TLS3_k127_8238232_6 Pfam:DUF59 - - - 0.0000000000000000000000000000002585 126.0
TLS3_k127_8238232_7 - - - - 0.0000000000000000000000000001531 121.0
TLS3_k127_8288543_0 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 1.871e-215 679.0
TLS3_k127_8288543_1 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00819,K00821 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 7.389e-212 662.0
TLS3_k127_8288543_10 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000003186 222.0
TLS3_k127_8288543_11 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000009792 223.0
TLS3_k127_8288543_13 PFAM short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000002408 180.0
TLS3_k127_8288543_14 DinB superfamily - - - 0.00009039 52.0
TLS3_k127_8288543_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 480.0
TLS3_k127_8288543_3 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 455.0
TLS3_k127_8288543_4 Aminotransferase, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 448.0
TLS3_k127_8288543_5 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 341.0
TLS3_k127_8288543_6 Belongs to the pyruvate kinase family K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008098 328.0
TLS3_k127_8288543_7 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03214,K03218,K03437,K21514 - 2.1.1.185,2.1.1.208 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 316.0
TLS3_k127_8288543_8 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 321.0
TLS3_k127_8288543_9 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 310.0
TLS3_k127_8319045_0 Metalloenzyme superfamily - - - 0.000000000000000000000000000000000000000000000008154 184.0
TLS3_k127_8319045_1 Domain of unknown function (DUF4332) - - - 0.0000000000000000000000000000000000000001718 154.0
TLS3_k127_8319045_2 VIT family - - - 0.0000000000000000000000000000006758 131.0
TLS3_k127_8319573_0 Putative auto-transporter adhesin, head GIN domain - - - 0.0000000000000000000000006241 115.0
TLS3_k127_8319573_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000002266 101.0
TLS3_k127_8319573_2 - - - - 0.0000000000000002681 87.0
TLS3_k127_8319573_3 LuxR family transcriptional regulator - - - 0.0000001995 58.0
TLS3_k127_8348696_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 565.0
TLS3_k127_8348696_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 480.0
TLS3_k127_8348696_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009163 472.0
TLS3_k127_8348696_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 411.0
TLS3_k127_8348696_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 396.0
TLS3_k127_8348696_5 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 348.0
TLS3_k127_8348696_6 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000003821 235.0
TLS3_k127_8348696_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000211 148.0
TLS3_k127_8348696_9 Cell division protein FtsQ K03589 - - 0.000001196 60.0
TLS3_k127_8358481_0 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002529 243.0
TLS3_k127_8358481_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000003079 185.0
TLS3_k127_8358481_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000001818 162.0
TLS3_k127_8451238_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.022e-201 639.0
TLS3_k127_8451238_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 520.0
TLS3_k127_8451238_10 Septum formation initiator - - - 0.00000000003865 68.0
TLS3_k127_8451238_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 411.0
TLS3_k127_8451238_3 Enoyl-(Acyl carrier protein) reductase K00059,K00068 - 1.1.1.100,1.1.1.140 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009593 343.0
TLS3_k127_8451238_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006296 250.0
TLS3_k127_8451238_5 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000003782 251.0
TLS3_k127_8451238_6 SMART helix-turn-helix domain protein K15539 - - 0.000000000000000000000000000000000000000000000000000000001146 221.0
TLS3_k127_8451238_7 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002093 206.0
TLS3_k127_8451238_8 integral membrane protein - - - 0.000000000000000000000000000000000002865 143.0
TLS3_k127_8451238_9 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000000122 100.0
TLS3_k127_845635_0 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 410.0
TLS3_k127_845635_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000001108 213.0
TLS3_k127_845635_2 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039,K07235 - - 0.000000000000000000000000000009164 121.0
TLS3_k127_845635_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.0000000000003999 70.0
TLS3_k127_845635_4 YwiC-like protein - - - 0.0000000004183 70.0
TLS3_k127_8508643_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1113.0
TLS3_k127_8508643_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.735e-220 689.0
TLS3_k127_8508643_2 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000001009 243.0
TLS3_k127_8508643_3 Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000001278 221.0
TLS3_k127_8508643_4 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000001056 204.0
TLS3_k127_8508643_5 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000008925 188.0
TLS3_k127_8508643_6 TIGRFAM ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC K16012 - - 0.00000000000000000000000001199 111.0
TLS3_k127_8508643_8 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00005265 51.0
TLS3_k127_8517303_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 383.0
TLS3_k127_8517303_1 Peptidase_C39 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 384.0
TLS3_k127_8517303_10 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000002597 103.0
TLS3_k127_8517303_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 344.0
TLS3_k127_8517303_3 ferrous iron binding K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000004221 227.0
TLS3_k127_8517303_4 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000003151 194.0
TLS3_k127_8517303_5 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000001675 188.0
TLS3_k127_8517303_6 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000002917 160.0
TLS3_k127_8517303_7 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000007623 149.0
TLS3_k127_8517303_8 PFAM Diacylglycerol kinase, catalytic - - - 0.000000000000000000000000000000000145 146.0
TLS3_k127_8517303_9 - - - - 0.0000000000000000000000000003416 126.0
TLS3_k127_8526489_0 Heavy-metal-associated domain K17686 - 3.6.3.54 9.456e-256 809.0
TLS3_k127_8526489_1 ABC 3 transport family K11708 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 446.0
TLS3_k127_8526489_10 Rhodanese Homology Domain - - - 0.00000000000000000004049 96.0
TLS3_k127_8526489_11 ABC-2 family transporter protein K01992 - - 0.00000000000000000007688 93.0
TLS3_k127_8526489_13 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000004483 87.0
TLS3_k127_8526489_14 SMART Rhodanese domain protein - - - 0.00002191 47.0
TLS3_k127_8526489_2 PFAM ABC-3 protein K11709 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 445.0
TLS3_k127_8526489_3 Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 434.0
TLS3_k127_8526489_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 385.0
TLS3_k127_8526489_5 NAD+ binding K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 297.0
TLS3_k127_8526489_6 nitrogen compound transport K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004293 291.0
TLS3_k127_8526489_7 PFAM ABC transporter related K11710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001403 255.0
TLS3_k127_8526489_8 Protein of unknown function (DUF2785) - - - 0.0000000000000000000000000000000000000000000004163 181.0
TLS3_k127_8526489_9 PFAM regulatory protein, ArsR K21903 - - 0.000000000000000000000004299 104.0
TLS3_k127_899136_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 2.803e-225 701.0
TLS3_k127_899136_1 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 475.0
TLS3_k127_899136_12 - - - - 0.0000003356 53.0
TLS3_k127_899136_2 Peptidase M16 domain protein K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 482.0
TLS3_k127_899136_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 472.0
TLS3_k127_899136_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000278 216.0
TLS3_k127_899136_5 dihydroorotate dehydrogenase activity K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000452 167.0
TLS3_k127_899136_6 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000007308 139.0
TLS3_k127_899136_7 - - - - 0.0000000000000000000000000000000003848 143.0
TLS3_k127_899136_8 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000000006534 132.0
TLS3_k127_899136_9 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000003437 111.0
TLS3_k127_906291_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 354.0
TLS3_k127_906291_2 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 334.0
TLS3_k127_906291_3 Catechol dioxygenase N terminus K03381 - 1.13.11.1 0.00000000000000000000000000000000000000000000005029 178.0
TLS3_k127_906291_4 Aminotransferase class IV K00826 - 2.6.1.42 0.00001535 53.0
TLS3_k127_91244_0 Belongs to the carbamoyltransferase HypF family K04656 - - 1.047e-241 773.0
TLS3_k127_91244_1 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 523.0
TLS3_k127_91244_2 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 401.0
TLS3_k127_91244_3 Hydrogenase accessory protein HypB K03189,K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 308.0
TLS3_k127_91244_4 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000009582 115.0
TLS3_k127_91244_5 spore germination K03605 - - 0.0000000000000000000000001242 112.0
TLS3_k127_91244_6 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000000007031 101.0
TLS3_k127_91244_7 Belongs to the arginase family K01480,K18459 - 3.5.3.11,3.5.3.17 0.0000000000000000000003014 99.0
TLS3_k127_91244_8 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.00000000000000000008993 90.0
TLS3_k127_91244_9 GCN5-related N-acetyl-transferase K06975 - - 0.000000000000000072 84.0
TLS3_k127_934963_0 COGs COG3263 NhaP-type Na H and K H antiporter with a unique C-terminal domain K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 506.0
TLS3_k127_934963_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 486.0
TLS3_k127_934963_10 PFAM LmbE family protein - - - 0.00000000000000000000000000000000000000000002133 170.0
TLS3_k127_934963_11 RDD family - - - 0.000000000000000000000000001837 118.0
TLS3_k127_934963_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 370.0
TLS3_k127_934963_3 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 344.0
TLS3_k127_934963_4 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 325.0
TLS3_k127_934963_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000005868 236.0
TLS3_k127_934963_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000009809 200.0
TLS3_k127_934963_8 Belongs to the ComB family K05979 - 3.1.3.71 0.0000000000000000000000000000000000000000000000008771 182.0
TLS3_k127_934963_9 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000009391 177.0
TLS3_k127_947155_0 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K12528 - - 0.0 1279.0
TLS3_k127_947155_1 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 505.0
TLS3_k127_947155_2 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 346.0
TLS3_k127_947155_3 inorganic diphosphatase activity K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 333.0
TLS3_k127_947155_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000002023 248.0
TLS3_k127_947155_5 Rnk N-terminus K06140 - - 0.00000000000000000000000000000000000000002678 156.0
TLS3_k127_947155_6 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000001279 81.0
TLS3_k127_952170_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 314.0
TLS3_k127_952170_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001241 285.0
TLS3_k127_952170_2 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000225 267.0
TLS3_k127_952170_3 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001453 247.0
TLS3_k127_952170_4 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000009991 234.0
TLS3_k127_952170_5 carboxylic acid catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000003865 225.0
TLS3_k127_952170_7 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000005414 165.0
TLS3_k127_972687_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.135e-302 935.0