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Overview

ID MAG04053
Name TLS3_bin.36
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Fibrobacterota
Class Fibrobacteria
Order UBA11236
Family UBA11236
Genus Chersky-265
Species
Assembly information
Completeness (%) 82.1
Contamination (%) 5.68
GC content (%) 60.0
N50 (bp) 15,998
Genome size (bp) 5,658,348

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4025

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1003381_0 Sigma-54 interaction domain K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 572.0
TLS3_k127_1003381_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 406.0
TLS3_k127_1003381_10 stage II sporulation protein E K07315 - 3.1.3.3 0.00000000000000000000000000000000000000003548 172.0
TLS3_k127_1003381_12 cell redox homeostasis - - - 0.0000000000000000000000000001118 124.0
TLS3_k127_1003381_13 COGs COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain K07315 - 3.1.3.3 0.0000000000000000000000000008187 126.0
TLS3_k127_1003381_14 Gram-negative-bacterium-type cell wall biogenesis - - - 0.000000000000000000000000001615 126.0
TLS3_k127_1003381_15 beta-galactosidase activity - - - 0.000000000000000000000002026 117.0
TLS3_k127_1003381_16 cell redox homeostasis - - - 0.00000000000000000000006801 108.0
TLS3_k127_1003381_17 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000002881 106.0
TLS3_k127_1003381_18 Ferredoxin - - - 0.0000000000000002168 84.0
TLS3_k127_1003381_19 Acetyltransferase K03789 - 2.3.1.128 0.000000000000002332 85.0
TLS3_k127_1003381_2 protein with a von Willebrand factor type A (vWA) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 335.0
TLS3_k127_1003381_20 Glycoprotease family K14742 GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.000000004544 66.0
TLS3_k127_1003381_3 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000001405 274.0
TLS3_k127_1003381_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000002942 263.0
TLS3_k127_1003381_5 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000001729 224.0
TLS3_k127_1003381_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000001229 206.0
TLS3_k127_1003381_7 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.000000000000000000000000000000000000000000000000000004595 199.0
TLS3_k127_1003381_8 HDOD domain - - - 0.00000000000000000000000000000000000000000000000002417 190.0
TLS3_k127_1003381_9 pseudouridine synthase activity K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000001272 185.0
TLS3_k127_1003566_0 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004248 275.0
TLS3_k127_1003566_1 - - - - 0.00006864 54.0
TLS3_k127_102516_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 338.0
TLS3_k127_102516_1 PFAM Uncharacterised BCR, COG1937 K21600 - - 0.0000000000000000000000000002368 117.0
TLS3_k127_102516_2 Lysin motif K08307 - - 0.000000000000000000001839 104.0
TLS3_k127_1043627_0 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.0000000000000000000000000000000000000000000000000000000000001133 238.0
TLS3_k127_1043627_1 Thioredoxin-like - - - 0.000000000000000000000000004204 117.0
TLS3_k127_1043627_2 Protein of unknown function (DUF3570) - - - 0.0000000000000000000009396 109.0
TLS3_k127_1043627_3 DinB superfamily - - - 0.000000000000000001805 93.0
TLS3_k127_1043627_4 Domain of unknown function (DUF4266) - - - 0.000002799 53.0
TLS3_k127_1047040_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0 1332.0
TLS3_k127_1047040_1 Cytochrome c - - - 4.473e-231 723.0
TLS3_k127_1047040_10 domain protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000001226 209.0
TLS3_k127_1047040_12 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.00000000000000000000000000000000000000000000001072 172.0
TLS3_k127_1047040_13 addiction module antidote protein HigA K07110,K21686 - - 0.00000000000000000000000000000000000000000002672 171.0
TLS3_k127_1047040_14 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000005895 151.0
TLS3_k127_1047040_15 Type I restriction enzyme R protein N terminus (HSDR_N) K01153 - 3.1.21.3 0.0000000000000000000000000000008448 123.0
TLS3_k127_1047040_16 cyclic nucleotide binding K00384,K01999,K07001,K10914 - 1.8.1.9 0.00000000000000000000001106 107.0
TLS3_k127_1047040_17 Major facilitator K03301 - - 0.00000000000000000000005784 114.0
TLS3_k127_1047040_18 HsdM N-terminal domain K03427 - 2.1.1.72 0.0000000000000000000001866 97.0
TLS3_k127_1047040_19 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.00000000000000000003449 106.0
TLS3_k127_1047040_2 Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA K03498,K03499 GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 495.0
TLS3_k127_1047040_20 helix_turn_helix, Arsenical Resistance Operon Repressor K22298 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0044212,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000279 70.0
TLS3_k127_1047040_21 Trehalose utilisation K09992 - - 0.000000002253 70.0
TLS3_k127_1047040_22 Trehalose utilisation K09992 - - 0.0000000152 67.0
TLS3_k127_1047040_23 Surface antigen - - - 0.0000003 63.0
TLS3_k127_1047040_24 Glucose sorbosone - - - 0.00001325 57.0
TLS3_k127_1047040_25 guanyl-nucleotide exchange factor activity K14475,K20276 - - 0.00001802 57.0
TLS3_k127_1047040_3 Protein of unknown function (DUF1016) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 441.0
TLS3_k127_1047040_4 PhoD-like phosphatase K01113,K07093 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009657 424.0
TLS3_k127_1047040_5 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 352.0
TLS3_k127_1047040_6 TLC ATP/ADP transporter K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 359.0
TLS3_k127_1047040_7 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 330.0
TLS3_k127_1047040_8 membrane organization K07277 - - 0.0000000000000000000000000000000000000000000000000000000000001008 235.0
TLS3_k127_1047040_9 Domains Cache_1, HAMP, PAS, PAS K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000001545 239.0
TLS3_k127_1062601_0 glycoside hydrolase family 81 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 597.0
TLS3_k127_1062601_1 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 571.0
TLS3_k127_1062601_10 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000325 111.0
TLS3_k127_1062601_11 cellulose binding K00505 - 1.14.18.1 0.0000000000002916 83.0
TLS3_k127_1062601_12 HEAT repeats - - - 0.00000000006172 74.0
TLS3_k127_1062601_13 outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000001628 68.0
TLS3_k127_1062601_14 long-chain fatty acid transporting porin activity - - - 0.000000926 60.0
TLS3_k127_1062601_15 Histidine kinase-like ATPases - - - 0.00001807 54.0
TLS3_k127_1062601_16 - - - - 0.0004566 43.0
TLS3_k127_1062601_2 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 445.0
TLS3_k127_1062601_3 Belongs to the MurCDEF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 388.0
TLS3_k127_1062601_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56,3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001604 288.0
TLS3_k127_1062601_5 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000002951 239.0
TLS3_k127_1062601_6 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000003997 168.0
TLS3_k127_1062601_7 long-chain fatty acid transporting porin activity K06076 - - 0.00000000000000000000000000000000000000001167 169.0
TLS3_k127_1062601_8 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) K13694,K13695 - 3.4.17.13 0.0000000000000000000000000001726 117.0
TLS3_k127_1062601_9 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0000000000000000000000000009153 123.0
TLS3_k127_107476_0 Belongs to the glycosyl hydrolase 57 family K06044 - 5.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 563.0
TLS3_k127_107476_1 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 307.0
TLS3_k127_107476_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000002175 245.0
TLS3_k127_1086509_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 409.0
TLS3_k127_1086509_1 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000001197 229.0
TLS3_k127_1086509_2 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000001551 221.0
TLS3_k127_1086509_3 penicillin binding - - - 0.000000000000000000000000000000000000000000000000001328 201.0
TLS3_k127_1086509_4 entry into host K13735 - - 0.000000000000000001416 102.0
TLS3_k127_1095498_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 329.0
TLS3_k127_1095498_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.0000000000000000000000000000000000000000000001201 174.0
TLS3_k127_1104584_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 450.0
TLS3_k127_1104584_1 His Kinase A (phospho-acceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 424.0
TLS3_k127_1104584_10 OmpA family - - - 0.000000000000000005505 94.0
TLS3_k127_1104584_2 COG1718 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 376.0
TLS3_k127_1104584_3 DegT/DnrJ/EryC1/StrS aminotransferase family K02805,K13010 - 2.6.1.102,2.6.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 319.0
TLS3_k127_1104584_4 UPF0114 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004899 263.0
TLS3_k127_1104584_5 RESPONSE REGULATOR receiver - - - 0.00000000000000000000000000000000000000000000000000000007677 198.0
TLS3_k127_1104584_6 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA - - - 0.0000000000000000000000000000000000000002657 151.0
TLS3_k127_1104584_7 Nucleotide pyrophosphohydrolase - - - 0.000000000000000000000000000000000001391 145.0
TLS3_k127_1104584_8 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000000012 130.0
TLS3_k127_1104584_9 Glycosyltransferase like family 2 K20444 - - 0.000000000000000000000002683 117.0
TLS3_k127_1108111_0 Protein conserved in bacteria - - - 3.888e-276 876.0
TLS3_k127_1108111_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 326.0
TLS3_k127_1108111_10 RNA cap guanine-N2 methyltransferase - - - 0.000000000000000000000000000000000000000000000000001129 199.0
TLS3_k127_1108111_11 protein methyltransferase activity K02687 - - 0.0000000000000000000000000000000000000000000000001296 187.0
TLS3_k127_1108111_12 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000002844 160.0
TLS3_k127_1108111_13 Glycosyl transferases group 1 - - - 0.00000000000000000000000000001028 134.0
TLS3_k127_1108111_14 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000001874 118.0
TLS3_k127_1108111_15 Glycosyltransferase family 9 (heptosyltransferase) K02841,K02843 - - 0.00000000000000000000000492 117.0
TLS3_k127_1108111_16 Glycosyltransferase WbsX - - - 0.00000000000000000000336 109.0
TLS3_k127_1108111_17 Polysaccharide biosynthesis protein - - - 0.00000000000000000001015 107.0
TLS3_k127_1108111_18 Methyltransferase domain - - - 0.00000000000000001157 86.0
TLS3_k127_1108111_19 Protein of unknown function (DUF2662) - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.00000000000000002697 84.0
TLS3_k127_1108111_2 geranylgeranyl reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 315.0
TLS3_k127_1108111_20 Transcriptional regulatory protein, C terminal - - - 0.00000000000000006082 93.0
TLS3_k127_1108111_21 glycosyl transferase family 2 - - - 0.0000000000000002335 90.0
TLS3_k127_1108111_22 - K00176,K07138 - 1.2.7.3 0.0000000000000005615 80.0
TLS3_k127_1108111_23 PFAM Glycosyl transferase, group 1 - - - 0.000000000000002267 89.0
TLS3_k127_1108111_24 Glycosyltransferase like family 2 - - - 0.000000000000007183 87.0
TLS3_k127_1108111_25 Glycosyl transferase - - - 0.00000004303 65.0
TLS3_k127_1108111_27 O-Antigen ligase - - - 0.0001238 55.0
TLS3_k127_1108111_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001982 287.0
TLS3_k127_1108111_4 isoprenoid biosynthetic process K00805,K02251,K02523 - 2.5.1.30,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000001209 272.0
TLS3_k127_1108111_5 CobQ CobB MinD ParA nucleotide binding domain K16554,K16692 - - 0.0000000000000000000000000000000000000000000000000000000000000000001517 242.0
TLS3_k127_1108111_6 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000004397 243.0
TLS3_k127_1108111_7 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000004445 236.0
TLS3_k127_1108111_8 CoA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000003081 207.0
TLS3_k127_1108111_9 pseudouridine synthase activity K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000005246 202.0
TLS3_k127_1119638_0 Protein of unknown function (DUF1538) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 291.0
TLS3_k127_1119638_1 Protein of unknown function (DUF1538) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001511 245.0
TLS3_k127_1119638_2 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000003099 236.0
TLS3_k127_1119638_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000003253 196.0
TLS3_k127_1119638_4 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000003348 177.0
TLS3_k127_1119638_5 Belongs to the P(II) protein family - - - 0.00000000000000000000000000000000007638 136.0
TLS3_k127_1119638_6 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564 - 0.00001021 56.0
TLS3_k127_1128168_0 DNA-templated transcription, termination K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 287.0
TLS3_k127_1128168_1 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003791 289.0
TLS3_k127_1128168_2 pyrroline-5-carboxylate reductase activity K00286 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.5.1.2 0.000000000000000000000000000000000000000000000000000002735 200.0
TLS3_k127_1128168_3 Bacterial regulatory proteins, tetR family K16137 - - 0.00000000000000000000000000003172 128.0
TLS3_k127_1138465_0 TIGRFAM DNA topoisomerase III, bacteria and conjugative plasmid K03169 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 567.0
TLS3_k127_1138465_1 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 423.0
TLS3_k127_1138465_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0080090,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 392.0
TLS3_k127_1138465_3 pseudouridine synthase activity K06180 GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 291.0
TLS3_k127_1138465_4 Squalene phytoene synthase K00801 - 2.5.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000008342 277.0
TLS3_k127_1138465_5 phosphoenolpyruvate-protein phosphotransferase activity K07683,K08483,K08484,K10851 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698 2.7.13.3,2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000003808 244.0
TLS3_k127_1138465_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000003577 137.0
TLS3_k127_114797_0 PFAM PrkA AAA domain K07180 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 552.0
TLS3_k127_114797_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 417.0
TLS3_k127_114797_2 SpoVR like protein K06415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 366.0
TLS3_k127_114797_3 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814,K11755 GO:0000105,GO:0003674,GO:0003824,GO:0003949,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31,5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 337.0
TLS3_k127_114797_4 Protein of unknown function (DUF444) K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001932 287.0
TLS3_k127_114797_5 proteolysis - - - 0.00000000000000000000000000000000000000008874 163.0
TLS3_k127_114797_6 protein secretion K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000006957 72.0
TLS3_k127_1155204_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 492.0
TLS3_k127_1155204_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 340.0
TLS3_k127_1155204_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001388 280.0
TLS3_k127_1155204_3 CbiX K03795 - 4.99.1.3 0.00000000000000001624 87.0
TLS3_k127_1155204_4 STAS domain - - - 0.0000000408 59.0
TLS3_k127_1156746_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000001913 226.0
TLS3_k127_1156746_1 - K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000001168 205.0
TLS3_k127_1156746_2 by modhmm - - - 0.0000000000000000000000000002461 132.0
TLS3_k127_1156746_3 Cadherin-like beta sandwich domain - - - 0.0000006889 62.0
TLS3_k127_1167357_0 TIGRFAM D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000001441 154.0
TLS3_k127_1167357_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000004942 141.0
TLS3_k127_1167357_2 Histidine kinase - - - 0.00000000000000000003235 95.0
TLS3_k127_1167357_3 HD domain protein K08722 - 3.1.3.89 0.00000000000392 75.0
TLS3_k127_1167357_4 self proteolysis K04771 - 3.4.21.107 0.0001634 53.0
TLS3_k127_1180950_0 Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 611.0
TLS3_k127_1180950_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K01876,K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 565.0
TLS3_k127_1180950_10 chemotaxis protein K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008614 352.0
TLS3_k127_1180950_11 Type ii and iii secretion system protein K02453,K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 351.0
TLS3_k127_1180950_12 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 315.0
TLS3_k127_1180950_13 ATPase activity K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003937 261.0
TLS3_k127_1180950_14 long-chain fatty acid transporting porin activity K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002958 257.0
TLS3_k127_1180950_15 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007698 263.0
TLS3_k127_1180950_16 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000001229 243.0
TLS3_k127_1180950_17 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000006745 209.0
TLS3_k127_1180950_18 tRNA (guanine-N7-)-methyltransferase activity K02493,K02527,K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.297,2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000001343 194.0
TLS3_k127_1180950_19 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000000000000000000891 186.0
TLS3_k127_1180950_2 CheA signal transduction histidine kinase K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 529.0
TLS3_k127_1180950_20 PFAM NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000001597 174.0
TLS3_k127_1180950_21 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000004891 150.0
TLS3_k127_1180950_22 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000001034 154.0
TLS3_k127_1180950_23 response regulator receiver K03413 - - 0.0000000000000000000000000000000000006967 143.0
TLS3_k127_1180950_24 Chemotaxis phosphatase CheX K03409 - - 0.0000000000000000000000000000000000211 140.0
TLS3_k127_1180950_25 Chemotaxis phosphatase CheX K03409 - - 0.0000000000000000000000000000000002966 137.0
TLS3_k127_1180950_26 phosphorelay signal transduction system - - - 0.00000000000000000000000000000004382 129.0
TLS3_k127_1180950_27 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000002492 120.0
TLS3_k127_1180950_28 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000007061 115.0
TLS3_k127_1180950_29 OsmC-like protein K07397 - - 0.000000000000000000000007246 112.0
TLS3_k127_1180950_3 queuine tRNA-ribosyltransferase activity K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 483.0
TLS3_k127_1180950_30 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K19591,K22491 - - 0.000000000000000000699 99.0
TLS3_k127_1180950_31 phosphorelay signal transduction system - - - 0.000000000000000008936 87.0
TLS3_k127_1180950_32 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000001934 87.0
TLS3_k127_1180950_33 Putative zinc- or iron-chelating domain - - - 0.00000000000000003096 92.0
TLS3_k127_1180950_34 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor - - - 0.0000000001668 66.0
TLS3_k127_1180950_35 photosynthesis - - - 0.00000002777 67.0
TLS3_k127_1180950_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 471.0
TLS3_k127_1180950_5 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 466.0
TLS3_k127_1180950_6 PFAM type II secretion system protein E K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 409.0
TLS3_k127_1180950_7 Histidine Phosphotransfer domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 424.0
TLS3_k127_1180950_8 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 403.0
TLS3_k127_1180950_9 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 358.0
TLS3_k127_1205906_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.303e-250 794.0
TLS3_k127_1205906_1 Amino acid permease - - - 3.314e-233 739.0
TLS3_k127_1205906_10 BlaR1 peptidase M56 - - - 0.0000181 55.0
TLS3_k127_1205906_11 Zinc finger (C3HC4-type RING finger) family protein - - - 0.0007732 53.0
TLS3_k127_1205906_2 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 586.0
TLS3_k127_1205906_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 443.0
TLS3_k127_1205906_4 DNA adenine methylase K06223 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 310.0
TLS3_k127_1205906_6 MotA TolQ ExbB proton channel family K03561 - - 0.000000000000000000001357 102.0
TLS3_k127_1205906_7 Biopolymer transport protein ExbD/TolR - - - 0.00000000002992 70.0
TLS3_k127_1205906_8 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000008607 68.0
TLS3_k127_1205906_9 Belongs to the peptidase S8 family - - - 0.000002502 54.0
TLS3_k127_1236290_0 argininosuccinate lyase activity K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 500.0
TLS3_k127_1236290_1 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 372.0
TLS3_k127_1236290_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000007422 208.0
TLS3_k127_1236290_3 MFS_1 like family - - - 0.0000000000000000000000000000000000000002853 167.0
TLS3_k127_1236290_4 addiction module antidote protein HigA K07110,K21686 - - 0.000000000000000000000000000000000144 145.0
TLS3_k127_1236290_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000002467 96.0
TLS3_k127_1236290_6 serine-type endopeptidase activity - - - 0.0000000005917 73.0
TLS3_k127_1236290_7 amine dehydrogenase activity - - - 0.000402 53.0
TLS3_k127_1254890_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 312.0
TLS3_k127_1254890_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000003283 206.0
TLS3_k127_1254890_2 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000006326 207.0
TLS3_k127_1254890_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000015 160.0
TLS3_k127_1254890_4 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.00000000000004449 76.0
TLS3_k127_1256420_0 penicillin binding K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 535.0
TLS3_k127_1256420_1 Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 469.0
TLS3_k127_1256420_2 peptidoglycan glycosyltransferase activity K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002398 283.0
TLS3_k127_1256420_3 regulation of cell shape K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 - 0.00000000000000000000000000000000000000000001794 173.0
TLS3_k127_1256420_4 competence protein - - - 0.00000000000000000000000000004354 128.0
TLS3_k127_1256420_5 rod shape-determining protein MreD K03571 - - 0.000000000000000000007376 98.0
TLS3_k127_1260369_0 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 0.0 1148.0
TLS3_k127_1260369_1 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 585.0
TLS3_k127_1260369_10 COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003233 246.0
TLS3_k127_1260369_11 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001498 261.0
TLS3_k127_1260369_12 - - - - 0.0000000000000000000000000000000000000000000000000000002446 199.0
TLS3_k127_1260369_13 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000009412 196.0
TLS3_k127_1260369_14 HDOD domain - - - 0.00000000000000000000000000000000000000000000000001016 195.0
TLS3_k127_1260369_15 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000004653 177.0
TLS3_k127_1260369_16 protein trimerization K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000009258 189.0
TLS3_k127_1260369_17 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000001401 178.0
TLS3_k127_1260369_18 PFAM L-asparaginase II - - - 0.00000000000000000000000000000000000000003813 165.0
TLS3_k127_1260369_19 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 0.0000000000000000000000000000000000000003743 168.0
TLS3_k127_1260369_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 451.0
TLS3_k127_1260369_20 PFAM Rhodanese-like domain - - - 0.0000000000000000000000000000004045 124.0
TLS3_k127_1260369_21 Rubredoxin - - - 0.000000000000000001722 90.0
TLS3_k127_1260369_22 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000008437 90.0
TLS3_k127_1260369_23 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000001685 87.0
TLS3_k127_1260369_24 - - - - 0.000000000000004737 81.0
TLS3_k127_1260369_25 Tetratricopeptide repeat - - - 0.0000000000007391 79.0
TLS3_k127_1260369_26 - - - - 0.00000000005752 71.0
TLS3_k127_1260369_27 - - - - 0.00001922 55.0
TLS3_k127_1260369_3 NADPH:quinone reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 413.0
TLS3_k127_1260369_4 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 367.0
TLS3_k127_1260369_5 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 351.0
TLS3_k127_1260369_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 340.0
TLS3_k127_1260369_7 sigma factor activity K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 319.0
TLS3_k127_1260369_8 WG containing repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002646 278.0
TLS3_k127_1260369_9 diguanylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005023 264.0
TLS3_k127_1265182_0 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 5.391e-271 850.0
TLS3_k127_1265182_1 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 448.0
TLS3_k127_1265182_2 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000000009121 110.0
TLS3_k127_1265182_3 domain, Protein - - - 0.0006821 53.0
TLS3_k127_1267828_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 9.869e-279 876.0
TLS3_k127_1267828_1 NMT1-like family K15576 - - 7.063e-205 646.0
TLS3_k127_1267828_10 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000003703 128.0
TLS3_k127_1267828_11 - - - - 0.000000000000000000000000001369 114.0
TLS3_k127_1267828_12 Putative DNA-binding domain - - - 0.000000000000000000001183 106.0
TLS3_k127_1267828_13 RelE toxin of RelE / RelB toxin-antitoxin system - - - 0.0000000000000001723 84.0
TLS3_k127_1267828_15 - K07726 - - 0.0001057 49.0
TLS3_k127_1267828_2 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 434.0
TLS3_k127_1267828_3 TIGRFAM nitrate ABC transporter, ATPase subunits C and D K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 402.0
TLS3_k127_1267828_4 Binding-protein-dependent transport system inner membrane component K15577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 370.0
TLS3_k127_1267828_5 sulfuric ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 383.0
TLS3_k127_1267828_6 Protein of unknown function (DUF692) K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 314.0
TLS3_k127_1267828_7 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005811 274.0
TLS3_k127_1267828_8 Protein of unknown function (DUF1398) - - - 0.0000000000000000000000000000000000000000000000000000000000000006771 221.0
TLS3_k127_1267828_9 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000009497 156.0
TLS3_k127_1281274_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 1.226e-289 919.0
TLS3_k127_1281274_1 ATP synthase alpha/beta family, nucleotide-binding domain K02412 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008542 524.0
TLS3_k127_1281274_10 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - 0.000000000000000000000000000000489 134.0
TLS3_k127_1281274_11 Flagellar hook-basal body complex protein FliE K02408 - - 0.00000000000000000187 87.0
TLS3_k127_1281274_12 Putative auto-transporter adhesin, head GIN domain - - - 0.00000000000002423 84.0
TLS3_k127_1281274_13 flagellar export protein FliJ K02413 - - 0.00001187 53.0
TLS3_k127_1281274_14 protein serine/threonine kinase activity K08873 GO:0000003,GO:0000184,GO:0000956,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006401,GO:0006402,GO:0006403,GO:0006405,GO:0006406,GO:0006464,GO:0006468,GO:0006611,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0006950,GO:0006974,GO:0007275,GO:0007548,GO:0008104,GO:0008150,GO:0008152,GO:0008406,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0015031,GO:0015833,GO:0015931,GO:0016070,GO:0016071,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018105,GO:0018193,GO:0018209,GO:0019219,GO:0019222,GO:0019439,GO:0019538,GO:0019637,GO:0022414,GO:0030258,GO:0030539,GO:0031323,GO:0031503,GO:0031974,GO:0031981,GO:0032204,GO:0032501,GO:0032502,GO:0033036,GO:0033043,GO:0033044,GO:0033554,GO:0034613,GO:0034641,GO:0034655,GO:0036211,GO:0040035,GO:0042162,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045137,GO:0045184,GO:0046483,GO:0046486,GO:0046488,GO:0046661,GO:0046700,GO:0046777,GO:0046834,GO:0046854,GO:0046907,GO:0048513,GO:0048519,GO:0048583,GO:0048608,GO:0048731,GO:0048806,GO:0048856,GO:0050657,GO:0050658,GO:0050789,GO:0050794,GO:0050896,GO:0051028,GO:0051052,GO:0051128,GO:0051168,GO:0051169,GO:0051171,GO:0051179,GO:0051234,GO:0051236,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0070727,GO:0071025,GO:0071027,GO:0071028,GO:0071030,GO:0071166,GO:0071426,GO:0071427,GO:0071702,GO:0071704,GO:0071705,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0140096,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901575,GO:2001020 2.7.11.1 0.00003223 51.0
TLS3_k127_1281274_15 Flagellar assembly protein FliH K02411 - - 0.00009766 53.0
TLS3_k127_1281274_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 479.0
TLS3_k127_1281274_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 462.0
TLS3_k127_1281274_4 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 GO:0001539,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006928,GO:0006935,GO:0006996,GO:0008150,GO:0009288,GO:0009425,GO:0009605,GO:0009987,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0040011,GO:0042221,GO:0042330,GO:0042802,GO:0042803,GO:0042995,GO:0043226,GO:0043228,GO:0044085,GO:0044403,GO:0044419,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0044780,GO:0044781,GO:0046982,GO:0046983,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243,GO:0070925,GO:0071840,GO:0071944,GO:0071973,GO:0071978,GO:0097588 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 428.0
TLS3_k127_1281274_5 bacterial-type flagellum-dependent cell motility K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 321.0
TLS3_k127_1281274_6 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.000000000000000000000000000000000000000000000004918 180.0
TLS3_k127_1281274_7 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.00000000000000000000000000000000000000000004245 180.0
TLS3_k127_1281274_8 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000004889 171.0
TLS3_k127_1281274_9 converts alpha-aldose to the beta-anomer - - - 0.00000000000000000000000000000005561 137.0
TLS3_k127_1284011_0 Chromate K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 412.0
TLS3_k127_1285446_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 514.0
TLS3_k127_1285446_1 iron-sulfur transferase activity K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000006109 196.0
TLS3_k127_1285446_2 iron-sulfur cluster assembly K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136 - 0.00000000000000000000000000000000000000005411 169.0
TLS3_k127_1285446_3 ATPase activity K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.000000000000000000000000000001887 121.0
TLS3_k127_1289709_0 ammonium transporteR K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 569.0
TLS3_k127_1289709_1 Branched-chain amino acid transport system / permease component K01995,K01998,K11961 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 432.0
TLS3_k127_1289709_2 Ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 317.0
TLS3_k127_1289709_3 abc transporter atp-binding protein K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008065 287.0
TLS3_k127_1289709_4 ATPases associated with a variety of cellular activities K11963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001576 267.0
TLS3_k127_1289709_5 Branched-chain amino acid transport system / permease component K01997,K11960 - - 0.00000000000000000000000000000000000000000001885 164.0
TLS3_k127_129251_0 TonB dependent receptor K02014 - - 0.0 1130.0
TLS3_k127_129251_1 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 419.0
TLS3_k127_129251_10 Rapid ALkalinization Factor (RALF) - - - 0.0008835 45.0
TLS3_k127_129251_2 - - - - 0.0000000000000000000000000000000000000000003824 170.0
TLS3_k127_129251_3 Belongs to the glycosyl hydrolase 11 (cellulase G) family K01181 - 3.2.1.8 0.000000000000000000000000000000000000001339 160.0
TLS3_k127_129251_4 AraC family transcriptional regulator K02854 - - 0.00000000000000004811 91.0
TLS3_k127_129251_5 electron transfer activity K05337 - - 0.0000000001329 64.0
TLS3_k127_129251_6 Pectate lyase K01728 - 4.2.2.2 0.000000003347 62.0
TLS3_k127_129251_7 Pectate lyase K01728 - 4.2.2.2 0.00000001805 64.0
TLS3_k127_129251_8 GDSL-like Lipase/Acylhydrolase - - - 0.000000947 59.0
TLS3_k127_129251_9 response regulator - - - 0.000005769 48.0
TLS3_k127_1296107_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008697 598.0
TLS3_k127_1296107_1 Anthranilate synthase component I, N terminal region K01665,K13950 - 2.6.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000801 555.0
TLS3_k127_1296107_2 Aminotransferase class-III K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 504.0
TLS3_k127_1296107_3 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.000000000000000000000000000000000000000000000000000000000000000002654 235.0
TLS3_k127_1296107_4 PFAM GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000006268 184.0
TLS3_k127_1296107_5 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000008272 158.0
TLS3_k127_1296107_6 Bacillithiol biosynthesis BshC K22136 - - 0.00000000000000000000000000000000124 149.0
TLS3_k127_1296107_7 phosphatidate phosphatase activity K19302 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.27 0.0000000000000000000000122 117.0
TLS3_k127_1296107_8 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000000000005141 66.0
TLS3_k127_1296107_9 transferase activity, transferring glycosyl groups K00754 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000001453 53.0
TLS3_k127_131842_0 Arsenical pump-driving ATPase K01551 - 3.6.3.16 4.55e-289 899.0
TLS3_k127_131842_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 453.0
TLS3_k127_131842_10 - - - - 0.00000000000000000000000000000000000001219 150.0
TLS3_k127_131842_11 PFAM TonB-dependent Receptor K16091 - - 0.0000000000000000000000000000000008696 134.0
TLS3_k127_131842_12 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000008986 140.0
TLS3_k127_131842_13 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000003251 136.0
TLS3_k127_131842_14 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000001438 118.0
TLS3_k127_131842_15 polysaccharide K01991,K20987 - - 0.00000000000000000000000002369 121.0
TLS3_k127_131842_16 Polysaccharide deacetylase - - - 0.00000000000000000000000008972 119.0
TLS3_k127_131842_17 PFAM lipopolysaccharide biosynthesis - - - 0.000000000000000000000872 111.0
TLS3_k127_131842_18 Glycosyl transferase - - - 0.0000000000000000001627 101.0
TLS3_k127_131842_19 hydrolase activity, acting on glycosyl bonds - - - 0.000000000008006 79.0
TLS3_k127_131842_2 Domain of unknown function (DUF1972) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 345.0
TLS3_k127_131842_20 O-antigen polymerase K18814 - - 0.0000000001087 74.0
TLS3_k127_131842_3 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 331.0
TLS3_k127_131842_4 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008589 319.0
TLS3_k127_131842_5 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03325,K03741,K03892,K18701 - 1.20.4.1,2.8.4.2,3.1.3.48 0.000000000000000000000000000000000000000000000000000002428 193.0
TLS3_k127_131842_6 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000253 200.0
TLS3_k127_131842_7 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000387 205.0
TLS3_k127_131842_8 ArsC family K00537 - 1.20.4.1 0.00000000000000000000000000000000000000000000000001348 184.0
TLS3_k127_131842_9 transcriptional regulator K03892 - - 0.00000000000000000000000000000000000000000000000005463 181.0
TLS3_k127_1327220_0 TIGRFAM MazG family protein K02499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004495 253.0
TLS3_k127_1327220_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000008627 247.0
TLS3_k127_1327220_2 DNA-templated transcription, termination K02600 GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000003834 206.0
TLS3_k127_1327220_3 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000003555 124.0
TLS3_k127_1327220_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00001694 53.0
TLS3_k127_1327220_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00005007 50.0
TLS3_k127_1420130_0 IMP dehydrogenase activity K00088 - 1.1.1.205 1.343e-221 698.0
TLS3_k127_1420130_1 phosphorelay signal transduction system K07712,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 460.0
TLS3_k127_1420130_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000892 366.0
TLS3_k127_1420130_3 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - 0.000000000000000000000000009486 111.0
TLS3_k127_142606_0 Belongs to the glycosyl hydrolase family 6 K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 593.0
TLS3_k127_142606_1 DNA photolyase activity K03716 - 4.1.99.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 320.0
TLS3_k127_142606_2 Protein of unknown function (DUF2797) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 309.0
TLS3_k127_142606_3 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000001127 261.0
TLS3_k127_142606_4 Zinc-uptake complex component A periplasmic K09815 - - 0.000000000000000000000000000000000000000000000000000000000002901 222.0
TLS3_k127_142606_5 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000008622 207.0
TLS3_k127_142606_6 ArsC family K00537 - 1.20.4.1 0.0000000000000000000000000000000000006963 147.0
TLS3_k127_142606_7 phosphate-selective porin O and P - - - 0.00000000000000000000000004487 121.0
TLS3_k127_142606_8 UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000002014 91.0
TLS3_k127_142606_9 Protein of unknown function (DUF4230) - - - 0.000000000000003656 85.0
TLS3_k127_1455346_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007979 385.0
TLS3_k127_1455346_1 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 331.0
TLS3_k127_1455346_2 Belongs to the methyltransferase superfamily K07444,K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 302.0
TLS3_k127_1455346_3 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001359 262.0
TLS3_k127_1455346_4 Domain of unknown function (DUF3473) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000178 265.0
TLS3_k127_1455346_5 xylan catabolic process - - - 0.0000000000000000000000000000000000000000000000000001127 216.0
TLS3_k127_1455346_6 COG2148 Sugar transferases involved in lipopolysaccharide synthesis - - - 0.00000000000000000000000000000000000000000004475 183.0
TLS3_k127_1455346_7 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000002181 105.0
TLS3_k127_1471967_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 572.0
TLS3_k127_1471967_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 560.0
TLS3_k127_1471967_10 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001223 288.0
TLS3_k127_1471967_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001543 260.0
TLS3_k127_1471967_12 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000861 232.0
TLS3_k127_1471967_13 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000002603 237.0
TLS3_k127_1471967_14 PFAM SMP-30 Gluconolaconase K01179,K01181,K01218,K02014 - 3.2.1.4,3.2.1.78,3.2.1.8 0.0000000000000000000000000000000000000000000000002759 200.0
TLS3_k127_1471967_15 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000658 190.0
TLS3_k127_1471967_16 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000001768 187.0
TLS3_k127_1471967_17 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000007058 181.0
TLS3_k127_1471967_18 O-Antigen ligase - - - 0.00000000000000000000000001587 124.0
TLS3_k127_1471967_19 TIGRFAM hydrolase, ortholog 2, exosortase system type 1 associated - - - 0.0000000000000000001073 100.0
TLS3_k127_1471967_2 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 523.0
TLS3_k127_1471967_20 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.000000000000006274 89.0
TLS3_k127_1471967_21 Acetyltransferase (GNAT) domain - - - 0.00001491 57.0
TLS3_k127_1471967_22 domain protein - - - 0.00005729 55.0
TLS3_k127_1471967_23 Phosphopantetheine attachment site - - - 0.0005335 50.0
TLS3_k127_1471967_3 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 471.0
TLS3_k127_1471967_4 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 479.0
TLS3_k127_1471967_5 asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 390.0
TLS3_k127_1471967_6 PFAM Orn DAP Arg decarboxylase 2 K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 364.0
TLS3_k127_1471967_7 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 357.0
TLS3_k127_1471967_8 COG0438 Glycosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 309.0
TLS3_k127_1471967_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000013 294.0
TLS3_k127_1525429_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000005912 192.0
TLS3_k127_1525429_1 ribonuclease BN K07058 - - 0.0000000000000000000000000001397 122.0
TLS3_k127_1525429_2 Transcriptional regulator, AbiEi antitoxin - - - 0.000000001071 61.0
TLS3_k127_1525429_3 Acetyltransferase (GNAT) domain - - - 0.00003634 54.0
TLS3_k127_1527541_0 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000000000000000001678 145.0
TLS3_k127_1527541_2 Ankyrin repeat - - - 0.000008677 58.0
TLS3_k127_1527541_3 DnaJ molecular chaperone homology domain - - - 0.000133 53.0
TLS3_k127_1559421_0 OPT oligopeptide transporter protein - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 1.908e-199 641.0
TLS3_k127_1559421_1 excinuclease ABC activity K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 461.0
TLS3_k127_1559421_10 50S ribosomal protein L31 K02909 - - 0.00000000000000000002575 94.0
TLS3_k127_1559421_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 387.0
TLS3_k127_1559421_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 312.0
TLS3_k127_1559421_4 Protein of unknown function (DUF1385) K09153 - - 0.0000000000000000000000000000000000000000000000000000000000000003241 238.0
TLS3_k127_1559421_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000002636 207.0
TLS3_k127_1559421_6 Bacterial protein of unknown function (DUF898) - - - 0.00000000000000000000000000000000000000000000000006364 190.0
TLS3_k127_1559421_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000008097 153.0
TLS3_k127_1559421_8 Peptidase family M48 - - - 0.000000000000000000000000000005146 134.0
TLS3_k127_1559421_9 - - - - 0.00000000000000000000000003693 111.0
TLS3_k127_1559819_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000925 513.0
TLS3_k127_1559819_1 sporulation resulting in formation of a cellular spore K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000009714 242.0
TLS3_k127_1559819_2 Sel1-like repeats. - - - 0.000000000000000000000006144 118.0
TLS3_k127_1559819_3 ThiS family K03154 - - 0.00000007749 61.0
TLS3_k127_1559819_4 protein conserved in bacteria - - - 0.000000209 54.0
TLS3_k127_1559819_5 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0002762 46.0
TLS3_k127_1642263_0 Peptidase family M3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 544.0
TLS3_k127_1642263_1 Transcriptional regulatory protein, C terminal K07663 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002835 271.0
TLS3_k127_1642263_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000002388 248.0
TLS3_k127_1642263_3 aconitate hydratase K01681 - 4.2.1.3 0.00000000000000000000000000000000003241 137.0
TLS3_k127_1642263_4 peptidyl-tyrosine sulfation - - - 0.0008268 51.0
TLS3_k127_165236_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000001133 213.0
TLS3_k127_165236_1 Belongs to the ClpA ClpB family K11907 - - 0.0000000000000000005219 91.0
TLS3_k127_1654341_0 Ribonucleotide reductase, all-alpha domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 351.0
TLS3_k127_1654341_1 cytochrome complex assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 346.0
TLS3_k127_1654341_2 Serine hydrolase K07002 - - 0.000000000000000000000000000000000000000000000000000004192 197.0
TLS3_k127_1654341_3 cytochrome c biogenesis protein K00523 - 1.17.1.1 0.0000000000000000000000000000000005543 146.0
TLS3_k127_1654341_4 - - - - 0.0004576 51.0
TLS3_k127_1682510_0 Glycosyl hydrolases family 8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 401.0
TLS3_k127_1682510_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 302.0
TLS3_k127_1682510_10 Transcriptional regulator K02529 - - 0.000007387 58.0
TLS3_k127_1682510_11 PFAM Extracellular ligand-binding receptor K01999 - - 0.00002568 49.0
TLS3_k127_1682510_12 UTRA K02043 - - 0.0002788 53.0
TLS3_k127_1682510_2 LemA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 290.0
TLS3_k127_1682510_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 299.0
TLS3_k127_1682510_4 Domain of unknown function (DUF4153) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001679 262.0
TLS3_k127_1682510_5 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000301 247.0
TLS3_k127_1682510_6 xyloglucan:xyloglucosyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000002811 233.0
TLS3_k127_1682510_7 TPM domain - - - 0.0000000000000000000000000000000000000000000000000000000000065 211.0
TLS3_k127_1682510_8 Pkd domain containing protein - - - 0.00000000000000000000000000000001244 141.0
TLS3_k127_1682510_9 - - - - 0.00000005396 57.0
TLS3_k127_1692706_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 624.0
TLS3_k127_1692706_1 Transcriptional regulator, TraR DksA family K06204 - - 0.000000000000000002803 91.0
TLS3_k127_1716289_0 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976,K19693,K21572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 511.0
TLS3_k127_1716289_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000172 239.0
TLS3_k127_1737824_1 regulation of translation K03530,K05788 - - 0.000000000000000000012 96.0
TLS3_k127_1737824_2 FlgD Ig-like domain - - - 0.00006305 57.0
TLS3_k127_1740629_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 333.0
TLS3_k127_1740629_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000009333 250.0
TLS3_k127_1740629_10 Protein of unknown function (DUF1161) - - - 0.00000000000004604 77.0
TLS3_k127_1740629_11 Curli production assembly/transport component CsgG - - - 0.00000004017 65.0
TLS3_k127_1740629_12 LPP20 lipoprotein - - - 0.000006024 59.0
TLS3_k127_1740629_13 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0006429 45.0
TLS3_k127_1740629_2 biopolymer transport protein K03559 - - 0.0000000000000000000000000000000000000002271 153.0
TLS3_k127_1740629_3 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000074 165.0
TLS3_k127_1740629_5 PA14 domain - - - 0.00000000000000000000000000000007664 145.0
TLS3_k127_1740629_6 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000148 126.0
TLS3_k127_1740629_8 TonB-dependent receptor plug domain - - - 0.00000000000000001249 98.0
TLS3_k127_1740629_9 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000003796 89.0
TLS3_k127_1750214_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 4.816e-290 899.0
TLS3_k127_1750214_1 Cation transporter/ATPase, N-terminus K01537 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.8 4.632e-267 844.0
TLS3_k127_1750214_10 DNA-templated transcription, initiation K03088 - - 0.000000000000000000001043 102.0
TLS3_k127_1750214_11 AntiSigma factor - - - 0.000000000001364 78.0
TLS3_k127_1750214_12 GyrI-like small molecule binding domain - - - 0.0000000000341 73.0
TLS3_k127_1750214_13 cheY-homologous receiver domain - - - 0.000000004351 63.0
TLS3_k127_1750214_14 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564 - 0.000002706 58.0
TLS3_k127_1750214_2 PFAM glycosyl transferase family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 7.735e-251 795.0
TLS3_k127_1750214_3 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 523.0
TLS3_k127_1750214_4 response regulator K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 415.0
TLS3_k127_1750214_5 Sodium hydrogen exchanger K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 326.0
TLS3_k127_1750214_6 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000003783 230.0
TLS3_k127_1750214_7 Histidine kinase - - - 0.000000000000000000000000000000000000000000006425 179.0
TLS3_k127_1750214_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000008187 169.0
TLS3_k127_1750214_9 COGs COG2905 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000000000000000000000001019 138.0
TLS3_k127_1792048_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 GO:0000166,GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005773,GO:0005774,GO:0006950,GO:0006970,GO:0006995,GO:0007154,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009266,GO:0009267,GO:0009268,GO:0009409,GO:0009605,GO:0009628,GO:0009651,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010446,GO:0016020,GO:0016491,GO:0016638,GO:0016639,GO:0017076,GO:0030554,GO:0031090,GO:0031667,GO:0031668,GO:0031669,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0035639,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043562,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0046686,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0051716,GO:0055114,GO:0071496,GO:0097159,GO:0097367,GO:0098588,GO:0098805,GO:1901265,GO:1901363,GO:1901698 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 400.0
TLS3_k127_1792048_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 310.0
TLS3_k127_1792048_11 iron-sulfur cluster assembly - - - 0.0000000000000000000000000000000000000005845 156.0
TLS3_k127_1792048_12 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000000000000000000000000002224 131.0
TLS3_k127_1792048_13 cheY-homologous receiver domain K07668 - - 0.0000000000000000000000000002046 118.0
TLS3_k127_1792048_14 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000001803 62.0
TLS3_k127_1792048_15 NusG domain II K00805 - 2.5.1.30 0.0000000004294 66.0
TLS3_k127_1792048_16 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.0000134 57.0
TLS3_k127_1792048_2 dihydroorotate dehydrogenase activity K00226,K00254,K02823,K17828 GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2,1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006805 311.0
TLS3_k127_1792048_3 Ion transport protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 303.0
TLS3_k127_1792048_4 regulation of circadian rhythm K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008733 291.0
TLS3_k127_1792048_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007558 273.0
TLS3_k127_1792048_6 lyase activity K01387,K03301 - 3.4.24.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000005338 278.0
TLS3_k127_1792048_7 cheY-homologous receiver domain K02485 - - 0.000000000000000000000000000000000000000000000000005986 191.0
TLS3_k127_1792048_8 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000009463 181.0
TLS3_k127_1792048_9 Glucose / Sorbosone dehydrogenase K08738 - - 0.0000000000000000000000000000000000000000000000001551 198.0
TLS3_k127_1793917_0 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 556.0
TLS3_k127_1797911_0 fatty acid biosynthetic process K03621,K21576,K21577 - 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 329.0
TLS3_k127_1797911_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 316.0
TLS3_k127_1797911_2 malonyl CoA-acyl carrier protein transacylase K00645,K15327,K15329,K15355,K15469 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000003543 268.0
TLS3_k127_1797911_3 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000001624 258.0
TLS3_k127_1797911_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000006228 54.0
TLS3_k127_180074_0 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000005623 192.0
TLS3_k127_180074_1 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000005337 181.0
TLS3_k127_180074_2 ABC transporter K02065 - - 0.00000000000000000000000000000000000001995 161.0
TLS3_k127_180074_3 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000000000000000000000000002889 150.0
TLS3_k127_180074_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000001408 56.0
TLS3_k127_1826276_0 PFAM Multi antimicrobial extrusion protein MatE K03327 - - 2.167e-221 694.0
TLS3_k127_1826276_1 PFAM Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 623.0
TLS3_k127_1826276_10 Xylose isomerase domain protein TIM barrel K18910 - 5.1.3.30,5.1.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 346.0
TLS3_k127_1826276_11 Phosphate-selective porin O and P K07221 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007407 342.0
TLS3_k127_1826276_12 Sodium:dicarboxylate symporter family K03309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 325.0
TLS3_k127_1826276_13 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001891 268.0
TLS3_k127_1826276_14 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000301 266.0
TLS3_k127_1826276_15 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003574 254.0
TLS3_k127_1826276_16 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000003671 238.0
TLS3_k127_1826276_17 Sterol-sensing domain of SREBP cleavage-activation K07003 - - 0.000000000000000000000000000000000000000000000000000000519 220.0
TLS3_k127_1826276_18 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000005249 199.0
TLS3_k127_1826276_19 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000002016 177.0
TLS3_k127_1826276_2 RimK-like ATPgrasp N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 482.0
TLS3_k127_1826276_20 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000004763 154.0
TLS3_k127_1826276_21 Acetyltransferase - - - 0.000000000000000000000000000000000000008664 151.0
TLS3_k127_1826276_22 Transcription factor zinc-finger - - - 0.00000000000000000000000000000000000001356 149.0
TLS3_k127_1826276_23 SMP-30 Gluconolaconase LRE-like K01053 - 3.1.1.17 0.000000000000000000000000000000002544 144.0
TLS3_k127_1826276_24 FAD binding domain - - - 0.00000000000002888 87.0
TLS3_k127_1826276_25 Phospholipase/Carboxylesterase K06999 - - 0.00000000000003464 82.0
TLS3_k127_1826276_27 Alpha-acetolactate decarboxylase K01575 - 4.1.1.5 0.0000315 50.0
TLS3_k127_1826276_3 Extracellular solute-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 471.0
TLS3_k127_1826276_4 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 449.0
TLS3_k127_1826276_5 BAAT / Acyl-CoA thioester hydrolase C terminal K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 398.0
TLS3_k127_1826276_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 389.0
TLS3_k127_1826276_7 ABC transporter K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 380.0
TLS3_k127_1826276_8 sulfate ABC transporter, inner membrane subunit CysT K02046,K15496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 366.0
TLS3_k127_1826276_9 Glutamate-cysteine ligase family 2(GCS2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 354.0
TLS3_k127_1831702_0 ftsk spoiiie K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 548.0
TLS3_k127_1831702_1 four-way junction helicase activity K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 441.0
TLS3_k127_1831702_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 318.0
TLS3_k127_1831702_3 Scramblase - - - 0.0000000000000000000000000000000000000000000000000000000001998 211.0
TLS3_k127_1831702_4 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000001879 201.0
TLS3_k127_1831702_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000002183 147.0
TLS3_k127_1831702_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000000000000000003134 136.0
TLS3_k127_1843665_0 addiction module antidote protein HigA K07110,K21686 - - 0.00000000000000000000000000000000000000000000000000000000000000000002447 243.0
TLS3_k127_1843665_1 glucose sorbosone K00117 - 1.1.5.2 0.00000000000000000000000000002227 135.0
TLS3_k127_1843665_2 Domain of unknown function (DUF2341) - - - 0.000000000000000000000001609 120.0
TLS3_k127_1848947_0 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 514.0
TLS3_k127_1848947_1 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 408.0
TLS3_k127_1848947_2 PFAM Bacterial extracellular solute-binding, family 1 K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 306.0
TLS3_k127_1848947_3 PFAM Nucleotidyl transferase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000751 270.0
TLS3_k127_1848947_4 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003156 274.0
TLS3_k127_1848947_5 PHP domain protein K01624,K07053 - 3.1.3.97,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000001593 237.0
TLS3_k127_1848947_6 heme binding K21471 - - 0.000000000000000000000000000000000000000009861 166.0
TLS3_k127_1848947_7 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07083,K11785 - - 0.00000000000000000000000000000000000005749 150.0
TLS3_k127_1848947_8 Belongs to the carbohydrate kinase PfkB family K00882,K00917,K16370 - 2.7.1.11,2.7.1.144,2.7.1.56 0.000000000000000000001696 106.0
TLS3_k127_1848947_9 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 3.2.2.26 0.00000000000008717 80.0
TLS3_k127_1910807_0 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 4.634e-216 695.0
TLS3_k127_1910807_1 ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 575.0
TLS3_k127_1910807_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000005411 186.0
TLS3_k127_1910807_3 protein conserved in bacteria K09906 - - 0.000000000000000000000000000000000000007442 155.0
TLS3_k127_1910807_4 PFAM Protein kinase - - - 0.000000000000000001048 100.0
TLS3_k127_1910807_5 Prion-inhibition and propagation - - - 0.0000002606 56.0
TLS3_k127_1913213_0 transcription-coupled nucleotide-excision repair, DNA damage recognition K03723,K05365 - 2.4.1.129,3.4.16.4 1.747e-279 897.0
TLS3_k127_1913213_1 phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005778 572.0
TLS3_k127_1913213_10 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000007615 200.0
TLS3_k127_1913213_11 bacteriocin transport K03561 - - 0.00000000000000000000000000000000000000000000000007579 196.0
TLS3_k127_1913213_12 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03087 - - 0.0000000000000000000000000000000000000000000001923 176.0
TLS3_k127_1913213_13 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000001214 167.0
TLS3_k127_1913213_14 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000003025 171.0
TLS3_k127_1913213_15 Methyltransferase domain - - - 0.000000000000000000000000000000000000000009613 164.0
TLS3_k127_1913213_16 biopolymer transport protein K03559 - - 0.000000000000000000000000000000000000002175 152.0
TLS3_k127_1913213_17 3-demethylubiquinone-9 3-O-methyltransferase activity K18827 - 2.1.1.294,2.7.1.181 0.000000000000000000000000000000000000006265 154.0
TLS3_k127_1913213_18 glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000001029 153.0
TLS3_k127_1913213_19 PFAM lipopolysaccharide biosynthesis - - - 0.000000000000000000000000000000000006975 152.0
TLS3_k127_1913213_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 425.0
TLS3_k127_1913213_20 Glycosyl transferase, family 2 K07011 - - 0.00000000000000000000000000000000007194 145.0
TLS3_k127_1913213_21 glycosyl transferase group 1 - - - 0.00000000000000000000000000001938 130.0
TLS3_k127_1913213_23 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000001489 122.0
TLS3_k127_1913213_24 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000002851 114.0
TLS3_k127_1913213_25 Yqey-like protein K09117 - - 0.000000000000000000003545 99.0
TLS3_k127_1913213_26 Glycosyl transferases group 1 K21001 - - 0.00000000000000000000434 106.0
TLS3_k127_1913213_27 polygalacturonase activity - - - 0.00000000000000000001979 106.0
TLS3_k127_1913213_28 PFAM Methyltransferase domain - - - 0.00000000000000002187 93.0
TLS3_k127_1913213_29 Fibronectin type 3 domain - - - 0.0000000000000000279 91.0
TLS3_k127_1913213_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 449.0
TLS3_k127_1913213_30 long-chain fatty acid transport protein - - - 0.0000000000005945 80.0
TLS3_k127_1913213_31 transcription factor binding - - - 0.000000000003528 67.0
TLS3_k127_1913213_32 protein conserved in bacteria - - - 0.000008774 50.0
TLS3_k127_1913213_33 O-Antigen ligase - - - 0.00001808 57.0
TLS3_k127_1913213_34 BFD-like [2Fe-2S] binding domain K00360 - - 0.00001848 54.0
TLS3_k127_1913213_35 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0007154,GO:0007165,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0015688,GO:0015833,GO:0015889,GO:0015891,GO:0015893,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019062,GO:0019904,GO:0022610,GO:0023052,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0031992,GO:0032991,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0042914,GO:0043213,GO:0044403,GO:0044406,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0044650,GO:0046813,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0051704,GO:0051716,GO:0060089,GO:0065007,GO:0071575,GO:0071702,GO:0071705,GO:0071944,GO:0098002,GO:0098552,GO:0098670,GO:0098796,GO:0098797,GO:1901678 - 0.000456 50.0
TLS3_k127_1913213_4 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 424.0
TLS3_k127_1913213_5 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 321.0
TLS3_k127_1913213_6 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002444 246.0
TLS3_k127_1913213_7 Macrocin-O-methyltransferase (TylF) - - - 0.0000000000000000000000000000000000000000000000000000000000000002556 234.0
TLS3_k127_1913213_8 polysaccharide export K01991 - - 0.00000000000000000000000000000000000000000000000000000006652 215.0
TLS3_k127_1913213_9 PFAM Methyltransferase type - - - 0.0000000000000000000000000000000000000000000000000000001249 201.0
TLS3_k127_1944076_0 Monogalactosyldiacylglycerol (MGDG) synthase K03429,K03715 - 2.4.1.315,2.4.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 425.0
TLS3_k127_1944076_1 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007959 415.0
TLS3_k127_1944076_10 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000002048 211.0
TLS3_k127_1944076_11 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000002023 182.0
TLS3_k127_1944076_12 Metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000005278 186.0
TLS3_k127_1944076_13 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000002316 172.0
TLS3_k127_1944076_14 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000005738 163.0
TLS3_k127_1944076_15 addiction module antidote protein HigA K07110,K21686 - - 0.000000000000000000000000004835 121.0
TLS3_k127_1944076_16 PA14 domain - - - 0.000000000000000000003265 109.0
TLS3_k127_1944076_17 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000000005596 99.0
TLS3_k127_1944076_19 histidine kinase A domain protein - - - 0.000004655 54.0
TLS3_k127_1944076_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 376.0
TLS3_k127_1944076_3 PFAM Amidohydrolase 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 379.0
TLS3_k127_1944076_4 Glycerol-3-phosphate dehydrogenase K00057 GO:0003674,GO:0003824,GO:0004367,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006072,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 356.0
TLS3_k127_1944076_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 357.0
TLS3_k127_1944076_6 HAD-hyrolase-like K01838 - 5.4.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002865 276.0
TLS3_k127_1944076_7 lipolytic protein G-D-S-L family K11751 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000001976 281.0
TLS3_k127_1944076_8 PFAM Response regulator receiver domain K07668 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001578 264.0
TLS3_k127_1944076_9 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001283 254.0
TLS3_k127_1967021_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 572.0
TLS3_k127_1967021_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000001288 216.0
TLS3_k127_1967021_2 addiction module antidote protein HigA K07110,K21686 - - 0.0000000000000000000000005531 114.0
TLS3_k127_1974605_0 protein catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 500.0
TLS3_k127_1974605_10 Transcriptional regulator - - - 0.000000001992 66.0
TLS3_k127_1974605_2 Glycosyltransferase like family 2 K00786,K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000191 306.0
TLS3_k127_1974605_3 PFAM Tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004342 278.0
TLS3_k127_1974605_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001344 240.0
TLS3_k127_1974605_5 Glycosyltransferase group 2 family protein - - - 0.00000000000000000000000000000000000001974 166.0
TLS3_k127_1974605_6 Protein of unknown function (DUF1778) - - - 0.00000000000000000000000000000000004828 136.0
TLS3_k127_1974605_7 - - - - 0.0000000000000000000000000008923 128.0
TLS3_k127_1974605_8 Protein of unknown function (DUF3570) - - - 0.000000000000002344 89.0
TLS3_k127_1974605_9 Protein of unknown function (DUF4197) - - - 0.0000000000001899 79.0
TLS3_k127_202572_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000457 279.0
TLS3_k127_202572_1 phosphohydrolase K06950 - - 0.00000000000000000000000000000000000000000000000000000000000000001223 231.0
TLS3_k127_202572_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001382 244.0
TLS3_k127_202572_3 HD domain - - - 0.00000000000000000000000000000000000000005672 167.0
TLS3_k127_202572_4 3D domain protein - - - 0.0000000000000000000000000000000001087 138.0
TLS3_k127_202572_5 energy transducer activity K03832 - - 0.0000000000000000000000000000000002452 144.0
TLS3_k127_202572_6 PFAM TfoX N-terminal domain K07343 - - 0.0000000000000000008066 91.0
TLS3_k127_202572_7 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000009576 83.0
TLS3_k127_202572_8 ATP-independent chaperone mediated protein folding - - - 0.000000000002059 73.0
TLS3_k127_2032360_0 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 492.0
TLS3_k127_2032360_1 bacteriocin transport K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 304.0
TLS3_k127_2032360_4 bacteriocin transport K03561 - - 0.00000000000000000000000000114 120.0
TLS3_k127_2032360_5 23S rRNA-intervening sequence protein - - - 0.00000000000000001047 88.0
TLS3_k127_2032360_6 Biopolymer transport protein ExbD K03559 - - 0.0001385 46.0
TLS3_k127_2043643_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 3.1e-267 838.0
TLS3_k127_2043643_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 497.0
TLS3_k127_2043643_2 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000001207 198.0
TLS3_k127_2043643_3 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000005018 203.0
TLS3_k127_2043643_4 Metallo-beta-lactamase superfamily K02238 - - 0.0000000000000000000000000000000000000000004574 168.0
TLS3_k127_2043643_5 OmpA family - - - 0.00000000002306 65.0
TLS3_k127_2045383_0 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 331.0
TLS3_k127_2045383_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000007655 240.0
TLS3_k127_2045383_2 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000002735 210.0
TLS3_k127_2045383_4 rRNA binding K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000001246 126.0
TLS3_k127_2045383_6 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000264 106.0
TLS3_k127_2045383_7 PFAM Glycosyl transferase, group 1 K12994 - 2.4.1.349 0.00000000000000000000001634 113.0
TLS3_k127_2045383_8 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000001754 101.0
TLS3_k127_2045383_9 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.3.13 0.00003737 50.0
TLS3_k127_2061773_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 587.0
TLS3_k127_2061773_1 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007902 486.0
TLS3_k127_2061773_2 L-malate dehydrogenase activity K00024 GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 404.0
TLS3_k127_2061773_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 393.0
TLS3_k127_2061773_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 385.0
TLS3_k127_2061773_5 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000003819 195.0
TLS3_k127_2061773_6 Leucine-rich repeat (LRR) protein - - - 0.0000000000000000000000000001256 135.0
TLS3_k127_2061773_7 Transcriptional regulator - - - 0.000000000000001256 83.0
TLS3_k127_2061773_8 protein, YhcH YjgK YiaL family - - - 0.0000000004979 63.0
TLS3_k127_2065117_0 SigmaW regulon antibacterial - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 437.0
TLS3_k127_2065117_1 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 353.0
TLS3_k127_2065117_2 tigr02147 - - - 0.00000000000003491 77.0
TLS3_k127_2065117_3 NfeD-like C-terminal, partner-binding - - - 0.0000000000001221 78.0
TLS3_k127_2095863_1 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000001175 137.0
TLS3_k127_2095863_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000003205 149.0
TLS3_k127_2095863_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000002349 91.0
TLS3_k127_2149774_0 Iron-containing alcohol dehydrogenase K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 471.0
TLS3_k127_2149774_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 412.0
TLS3_k127_2149774_10 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000005123 178.0
TLS3_k127_2149774_11 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000006133 113.0
TLS3_k127_2149774_12 Von Willebrand factor type A K07114 - - 0.00000000000004167 81.0
TLS3_k127_2149774_13 helix_turn_helix, Lux Regulon - - - 0.0000000000001278 78.0
TLS3_k127_2149774_14 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000007239 73.0
TLS3_k127_2149774_15 translation release factor activity - - - 0.000000003942 66.0
TLS3_k127_2149774_16 Phosphate-selective porin O and P - - - 0.0004862 53.0
TLS3_k127_2149774_2 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 359.0
TLS3_k127_2149774_3 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 306.0
TLS3_k127_2149774_4 FAE1/Type III polyketide synthase-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001305 292.0
TLS3_k127_2149774_5 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003144 292.0
TLS3_k127_2149774_6 phosphoprotein phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003083 274.0
TLS3_k127_2149774_7 Methionine biosynthesis protein MetW K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000007442 270.0
TLS3_k127_2149774_8 TIGRFAM Undecaprenyl-phosphate glucose phosphotransferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000016 261.0
TLS3_k127_2149774_9 Belongs to the pseudouridine synthase RsuA family K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20 0.00000000000000000000000000000000000000000000000000000000000000005215 232.0
TLS3_k127_2167475_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 431.0
TLS3_k127_2167475_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.000000000000000000000001196 108.0
TLS3_k127_2167475_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000004588 57.0
TLS3_k127_2224051_0 4Fe-4S dicluster domain K00184 - - 2.785e-280 895.0
TLS3_k127_2224051_1 Polysulphide reductase, NrfD K00185 - - 1.717e-207 654.0
TLS3_k127_2224051_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000006626 199.0
TLS3_k127_2224051_3 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000007253 186.0
TLS3_k127_2229528_0 Trehalose utilisation K09992 - - 0.00004091 56.0
TLS3_k127_2239923_0 Sigma-70 region 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 526.0
TLS3_k127_2239923_1 Activator of Hsp90 ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000107 246.0
TLS3_k127_2239923_2 Bacterial regulatory protein, arsR family - - - 0.0000000000000000000000000000000000000000008037 164.0
TLS3_k127_2239923_3 YCII-related domain - - - 0.0000000000000000000000000000000000000003525 153.0
TLS3_k127_2239923_4 methylamine metabolic process K15977 - - 0.00000000000000000000000000000000000001693 150.0
TLS3_k127_2239923_5 RibD C-terminal domain - - - 0.00000000000000000000000001856 112.0
TLS3_k127_2239923_6 - - - - 0.00001219 57.0
TLS3_k127_2240175_0 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 470.0
TLS3_k127_2240175_1 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 460.0
TLS3_k127_2240175_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 389.0
TLS3_k127_2240175_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 373.0
TLS3_k127_2240175_4 cellulose binding K01179,K21449 - 3.2.1.4 0.000000000000000000000002537 122.0
TLS3_k127_2240175_5 Domain of unknown function (DUF2341) - - - 0.0000000000000000000004676 115.0
TLS3_k127_2240175_6 Domain of unknown function (DUF4154) - - - 0.00000000000000000000149 101.0
TLS3_k127_2240175_7 Domain of unknown function (DUF4154) - - - 0.0000000000000000002634 96.0
TLS3_k127_2240175_8 Domain of Unknown Function (DUF1080) - - - 0.00001017 57.0
TLS3_k127_224456_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 8.69e-210 664.0
TLS3_k127_224456_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 570.0
TLS3_k127_224456_10 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000786 260.0
TLS3_k127_224456_11 5'-deoxynucleotidase activity K07023 - - 0.00000000000000000000000000000000000000000000000000003385 194.0
TLS3_k127_224456_12 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000001894 180.0
TLS3_k127_224456_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000007994 154.0
TLS3_k127_224456_14 PA14 domain - - - 0.00000000000000000000000000000000000142 159.0
TLS3_k127_224456_15 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062,K18828 - - 0.000000000000000000000000000000000002938 141.0
TLS3_k127_224456_16 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.00000000000000000000000000000000001811 151.0
TLS3_k127_224456_17 - K07071 - - 0.00000000000000000000000000000001484 131.0
TLS3_k127_224456_18 AntiSigma factor - - - 0.00000000000000000000000000002567 133.0
TLS3_k127_224456_19 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000006684 132.0
TLS3_k127_224456_2 Pirin C-terminal cupin domain K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 489.0
TLS3_k127_224456_20 Chitobiase/beta-hexosaminidase C-terminal domain K01183 - 3.2.1.14 0.0000000000000000000004043 112.0
TLS3_k127_224456_21 MTH538 TIR-like domain (DUF1863) - - - 0.0000000000000000002901 95.0
TLS3_k127_224456_22 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000005736 89.0
TLS3_k127_224456_23 - K18829 - - 0.00000000000000003526 93.0
TLS3_k127_224456_24 Trehalose utilisation K09992 - - 0.000000000000003487 87.0
TLS3_k127_224456_25 addiction module component - - - 0.0000000006782 63.0
TLS3_k127_224456_26 Tetratricopeptide repeat - - - 0.000000001881 70.0
TLS3_k127_224456_27 - - - - 0.000001382 56.0
TLS3_k127_224456_28 peptidyl-tyrosine sulfation - - - 0.00001099 59.0
TLS3_k127_224456_3 Predicted nucleotidyltransferase K07074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 409.0
TLS3_k127_224456_4 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 428.0
TLS3_k127_224456_5 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 324.0
TLS3_k127_224456_6 Nucleotidyltransferase K07074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 316.0
TLS3_k127_224456_7 Uncharacterized conserved protein (COG2071) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005013 273.0
TLS3_k127_224456_8 Glucose sorbosone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007503 277.0
TLS3_k127_224456_9 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000008318 265.0
TLS3_k127_2246406_0 carbohydrate transport K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 361.0
TLS3_k127_2246406_1 protein conserved in bacteria K09859 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 309.0
TLS3_k127_2246406_10 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) K07337,K21008 GO:0000270,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0019899,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043085,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044093,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000001461 223.0
TLS3_k127_2246406_11 Glutamine amido-transferase K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000002036 221.0
TLS3_k127_2246406_12 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000249 228.0
TLS3_k127_2246406_13 COG2148 Sugar transferases involved in lipopolysaccharide synthesis - - - 0.000000000000000000000000000000000000000001873 179.0
TLS3_k127_2246406_14 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000009857 169.0
TLS3_k127_2246406_15 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000679 139.0
TLS3_k127_2246406_16 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000003646 127.0
TLS3_k127_2246406_17 SnoaL-like domain - - - 0.00000000000000000009854 94.0
TLS3_k127_2246406_18 Domain of Unknown Function (DUF1080) - - - 0.000000000000000001215 98.0
TLS3_k127_2246406_19 CAAX protease self-immunity K07052 - - 0.000000000001271 80.0
TLS3_k127_2246406_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 291.0
TLS3_k127_2246406_20 Transposase - - - 0.00001955 52.0
TLS3_k127_2246406_21 Domain of unknown function (DUF4277) - - - 0.0001591 47.0
TLS3_k127_2246406_3 Sigma-54 interaction domain K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 303.0
TLS3_k127_2246406_4 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009387 293.0
TLS3_k127_2246406_5 Belongs to the ABC transporter superfamily K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002096 292.0
TLS3_k127_2246406_6 transmembrane transport K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000426 267.0
TLS3_k127_2246406_7 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000398 266.0
TLS3_k127_2246406_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000002416 243.0
TLS3_k127_2246406_9 Domain of unknown function (DUF3473) - - - 0.0000000000000000000000000000000000000000000000000000000000000001333 249.0
TLS3_k127_2248054_0 Cys/Met metabolism PLP-dependent enzyme K01761 - 4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 602.0
TLS3_k127_2248054_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 512.0
TLS3_k127_2248054_2 Lytic polysaccharide mono-oxygenase, cellulose-degrading K03933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 306.0
TLS3_k127_2248054_3 dithiol-disulfide isomerase involved in polyketide biosynthesis K01829 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000008683 253.0
TLS3_k127_2248054_4 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000001488 229.0
TLS3_k127_2248054_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000001703 218.0
TLS3_k127_2248054_6 Transcription factor zinc-finger - - - 0.000000000000000000000000000000000014 141.0
TLS3_k127_2248054_7 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000002264 117.0
TLS3_k127_2248054_8 Outer membrane protein beta-barrel domain - - - 0.000000000000000002841 95.0
TLS3_k127_2256681_0 proline dipeptidase activity K01262 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 396.0
TLS3_k127_2271256_0 GTP binding K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005706 281.0
TLS3_k127_2271256_1 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000007426 117.0
TLS3_k127_2271256_2 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07713,K07714,K19641 - - 0.000000000000000000000001041 109.0
TLS3_k127_2271256_3 Roadblock/LC7 domain K07131 - - 0.0000000000007244 73.0
TLS3_k127_2293000_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 362.0
TLS3_k127_2293000_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000096 361.0
TLS3_k127_2293000_2 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 344.0
TLS3_k127_2295823_0 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008204 369.0
TLS3_k127_2295823_1 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 350.0
TLS3_k127_2295823_2 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002614 240.0
TLS3_k127_2295823_3 - - - - 0.000000000000000000000000000000000000005366 151.0
TLS3_k127_2295823_4 PFAM YeeE YedE family (DUF395) K07112 - - 0.000000000000000000000000000000000001832 145.0
TLS3_k127_2295823_5 Transporter K07112 - - 0.0000000000000000000000000000000003343 135.0
TLS3_k127_2339164_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000009306 145.0
TLS3_k127_2339164_1 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000509 104.0
TLS3_k127_2339164_2 Trehalose utilisation K09992 - - 0.00001373 57.0
TLS3_k127_23819_0 transcription factor binding K02584,K21009 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 351.0
TLS3_k127_23819_1 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009197 346.0
TLS3_k127_23819_10 TIGRFAM RHS repeat-associated core domain - - - 0.00001449 54.0
TLS3_k127_23819_11 Tetratricopeptide repeat - - - 0.0001151 53.0
TLS3_k127_23819_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000003187 227.0
TLS3_k127_23819_3 translation release factor activity - - - 0.00000000000000000000000000000000000000001896 168.0
TLS3_k127_23819_4 SNARE associated Golgi protein K03975 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000008544 161.0
TLS3_k127_23819_5 Protein tyrosine kinase - - - 0.0000000000000000000000000001535 133.0
TLS3_k127_23819_6 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000005964 104.0
TLS3_k127_23819_7 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000002491 90.0
TLS3_k127_23819_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000005041 86.0
TLS3_k127_2395999_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008573 257.0
TLS3_k127_2395999_1 Tetratricopeptide repeat - - - 0.000000000000000393 93.0
TLS3_k127_2395999_2 - - - - 0.0000259 51.0
TLS3_k127_2419890_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0 1460.0
TLS3_k127_2419890_1 Nitrite and sulphite reductase 4Fe-4S K00362 - 1.7.1.15 0.0 1114.0
TLS3_k127_2419890_2 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009081 332.0
TLS3_k127_2419890_3 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 345.0
TLS3_k127_2419890_4 Transcriptional regulator, AbiEi antitoxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000003011 190.0
TLS3_k127_2419890_6 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.000000000000000000000004229 103.0
TLS3_k127_2419890_7 TIGRFAM nitrite reductase NAD(P)H , small subunit K00363 - 1.7.1.15 0.00000000000004976 74.0
TLS3_k127_2435399_0 PFAM cytochrome c oxidase, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000008474 214.0
TLS3_k127_2435399_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000004144 181.0
TLS3_k127_2435399_2 addiction module antidote protein HigA K07110,K21686 - - 0.0000000000000000001848 100.0
TLS3_k127_2435399_3 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.00000000000002105 76.0
TLS3_k127_2435399_4 binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription K03088 - - 0.000000000003825 76.0
TLS3_k127_2472644_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 409.0
TLS3_k127_2472644_1 peptidase activity, acting on L-amino acid peptides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 400.0
TLS3_k127_2472644_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000962 279.0
TLS3_k127_2472644_3 Protein conserved in bacteria - - - 0.0000000000000003795 92.0
TLS3_k127_2472644_4 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.00000000000001008 75.0
TLS3_k127_2472644_5 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000134 56.0
TLS3_k127_2474966_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000003138 146.0
TLS3_k127_2474966_1 MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000009002 101.0
TLS3_k127_2474966_2 TonB-dependent Receptor Plug K02014 - - 0.0000906 49.0
TLS3_k127_2492597_0 PFAM FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 544.0
TLS3_k127_2492597_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 464.0
TLS3_k127_2492597_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006709 456.0
TLS3_k127_2492597_3 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 333.0
TLS3_k127_2492597_4 Amb_all K01728 - 4.2.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 295.0
TLS3_k127_2492597_5 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000002341 149.0
TLS3_k127_2492597_7 lactoylglutathione lyase activity - - - 0.00001581 48.0
TLS3_k127_2492597_8 protein transport across the cell outer membrane K08084 - - 0.0004426 50.0
TLS3_k127_2503278_0 Membrane protein involved in D-alanine export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008201 292.0
TLS3_k127_2503278_1 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000001312 205.0
TLS3_k127_2503278_2 Non-ribosomal peptide synthetase modules and related proteins - - - 0.000000000000000000000000000000000000000000000000000000001186 215.0
TLS3_k127_2503278_3 Phosphopantetheine attachment site K02078 - - 0.000000001683 61.0
TLS3_k127_250544_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000006647 125.0
TLS3_k127_250544_1 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000261 118.0
TLS3_k127_250544_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.000000000000000002585 99.0
TLS3_k127_250544_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000004006 61.0
TLS3_k127_250544_4 Phospholipid methyltransferase - - - 0.00000227 58.0
TLS3_k127_2515190_0 lipopolysaccharide transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 547.0
TLS3_k127_2515190_1 glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006809 387.0
TLS3_k127_2515190_10 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000001552 156.0
TLS3_k127_2515190_11 Bacillithiol biosynthesis BshC K22136 - - 0.000000000000000000000000000000006311 146.0
TLS3_k127_2515190_12 carbon utilization K02664,K02665,K12280 - - 0.0000000000000000000000000000003988 130.0
TLS3_k127_2515190_13 PFAM Fimbrial assembly family protein K02663 - - 0.0000000000000000000000523 107.0
TLS3_k127_2515190_14 translation initiation factor activity - - - 0.0000000000000000000009114 111.0
TLS3_k127_2515190_15 Flagellar motor switch protein FliN K02417 - - 0.000000000000000000003628 95.0
TLS3_k127_2515190_16 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000001094 94.0
TLS3_k127_2515190_17 heme binding - - - 0.00000000000000001646 98.0
TLS3_k127_2515190_18 regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed - - - 0.0000000000000001995 93.0
TLS3_k127_2515190_19 SMART helix-turn-helix domain protein - - - 0.0000000003406 71.0
TLS3_k127_2515190_2 Type ii and iii secretion system protein K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 323.0
TLS3_k127_2515190_20 Protein tyrosine kinase - - - 0.0001277 49.0
TLS3_k127_2515190_3 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001162 266.0
TLS3_k127_2515190_4 imidazoleglycerol-phosphate dehydratase activity K00013,K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,2.6.1.9,3.1.3.15,4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000331 252.0
TLS3_k127_2515190_5 ABC transporter, ATP-binding protein K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000009471 226.0
TLS3_k127_2515190_6 PFAM GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000002605 179.0
TLS3_k127_2515190_7 HDOD domain - - - 0.000000000000000000000000000000000000000000004235 178.0
TLS3_k127_2515190_8 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000001672 157.0
TLS3_k127_2515190_9 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000003478 160.0
TLS3_k127_2534664_0 Glycosyl Transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 313.0
TLS3_k127_2534664_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000001542 223.0
TLS3_k127_2534664_2 DNA-directed DNA polymerase activity K02342,K03722,K03763 - 2.7.7.7,3.6.4.12 0.000000000000000000000000000000000000000000000008766 181.0
TLS3_k127_2534664_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000007098 110.0
TLS3_k127_2534664_4 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000009076 106.0
TLS3_k127_2534664_5 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000001393 93.0
TLS3_k127_2534664_7 PFAM Tetratricopeptide repeat K06877 - - 0.00003725 57.0
TLS3_k127_2541165_0 Aldehyde dehydrogenase family K06447 - 1.2.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 531.0
TLS3_k127_2541165_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K07250 - 2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 477.0
TLS3_k127_2541165_10 Rhomboid family - - - 0.00000000000000000000000000000000271 136.0
TLS3_k127_2541165_2 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) K01484 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009015,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.3.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 476.0
TLS3_k127_2541165_3 Oxidoreductase family, C-terminal alpha beta domain K00118,K13020 - 1.1.1.335,1.1.99.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 415.0
TLS3_k127_2541165_4 COG3138 Arginine ornithine N-succinyltransferase beta subunit K00673 - 2.3.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 369.0
TLS3_k127_2541165_5 Peptidase dimerisation domain K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 366.0
TLS3_k127_2541165_6 DUF1338 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 297.0
TLS3_k127_2541165_7 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009957 263.0
TLS3_k127_2541165_8 - - - - 0.0000000000000000000000000000000000000000000000000000007795 199.0
TLS3_k127_2541165_9 - - - - 0.00000000000000000000000000000000000000000000000000000873 201.0
TLS3_k127_2610669_0 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 385.0
TLS3_k127_2610669_1 cytokinin biosynthetic process K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006571 281.0
TLS3_k127_2610669_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000003695 217.0
TLS3_k127_2610669_3 bacterial-type flagellum-dependent cell motility K02388 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009425,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.000000000000000000000000000000000000000000000003895 177.0
TLS3_k127_2610669_4 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.0000000000000000000000000000006373 132.0
TLS3_k127_2610669_5 bacterial-type flagellum-dependent cell motility K02387 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.00000000000000000000002668 106.0
TLS3_k127_2612608_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.817e-274 867.0
TLS3_k127_2612608_1 PFAM Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 373.0
TLS3_k127_2612608_2 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004845 284.0
TLS3_k127_2612608_3 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000004001 211.0
TLS3_k127_2612608_4 phosphoserine phosphatase activity K07711 - 2.7.13.3 0.00000000000000000000002404 106.0
TLS3_k127_2635510_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0 1388.0
TLS3_k127_2635510_1 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.0 1068.0
TLS3_k127_2635510_10 Proto-chlorophyllide reductase 57 kd subunit - - - 0.0000000001488 76.0
TLS3_k127_2635510_2 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 492.0
TLS3_k127_2635510_3 Rubrerythrin K22405 - 1.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009088 489.0
TLS3_k127_2635510_4 Pyrroloquinoline quinone biosynthesis protein E - - - 0.0000000000000000000000000000000000000000000000000000000000000008749 224.0
TLS3_k127_2635510_5 Crp Fnr family K21563 - - 0.0000000000000000000000000000000000000000000001893 177.0
TLS3_k127_2635510_6 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000004231 145.0
TLS3_k127_2635510_7 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.000000000000000000000000000000000364 142.0
TLS3_k127_2635510_8 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000003781 113.0
TLS3_k127_2635510_9 component of anaerobic K03533 - - 0.0000000000000003123 88.0
TLS3_k127_2653738_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1241.0
TLS3_k127_2653738_1 TonB dependent receptor K02014 - - 1.173e-204 658.0
TLS3_k127_2653738_10 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000002682 220.0
TLS3_k127_2653738_11 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000003092 219.0
TLS3_k127_2653738_12 self proteolysis - - - 0.0000000000000000000000000000000000000000000001131 190.0
TLS3_k127_2653738_13 Histidine kinase - - - 0.0000000000000000000000000000000000000000000001299 190.0
TLS3_k127_2653738_14 - - - - 0.0000000000000000000000000000002993 127.0
TLS3_k127_2653738_15 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000000000004779 124.0
TLS3_k127_2653738_16 PFAM Membrane protein of K08972 - - 0.000000000000000000002162 100.0
TLS3_k127_2653738_17 MotA TolQ ExbB proton channel family K03561 - - 0.00000000000000000001067 102.0
TLS3_k127_2653738_18 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000006836 92.0
TLS3_k127_2653738_19 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000001314 90.0
TLS3_k127_2653738_2 Sigma-70 region 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 516.0
TLS3_k127_2653738_20 Antibiotic biosynthesis monooxygenase - - - 0.000000000000001666 79.0
TLS3_k127_2653738_21 - - - - 0.00000000000002011 75.0
TLS3_k127_2653738_22 LytTr DNA-binding domain - - - 0.0000000003617 65.0
TLS3_k127_2653738_23 Immune inhibitor A peptidase M6 - - - 0.0000005192 64.0
TLS3_k127_2653738_24 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0003281 53.0
TLS3_k127_2653738_3 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009829 452.0
TLS3_k127_2653738_4 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 448.0
TLS3_k127_2653738_5 PFAM Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 392.0
TLS3_k127_2653738_6 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 372.0
TLS3_k127_2653738_7 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000003114 267.0
TLS3_k127_2653738_8 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000008036 244.0
TLS3_k127_2653738_9 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003719 229.0
TLS3_k127_2658496_0 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000003188 237.0
TLS3_k127_2658496_1 TIGRFAM Amino acid adenylation K04786,K13611 - - 0.0000000000000000000000000000000000000000000000003954 184.0
TLS3_k127_2658496_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000387 167.0
TLS3_k127_2658496_3 GDP-mannose mannosyl hydrolase activity K03574,K08320 - 3.6.1.55,3.6.1.65 0.0000000000000000000000000001574 119.0
TLS3_k127_2658496_4 transferase activity, transferring acyl groups - - - 0.000001481 61.0
TLS3_k127_2661641_0 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 589.0
TLS3_k127_2661641_1 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 398.0
TLS3_k127_2661641_2 Protein of unknown function (DUF1428) - - - 0.000000000000000000000000000000000000001368 149.0
TLS3_k127_2661641_3 ThiS family - - - 0.00000000000000000001312 95.0
TLS3_k127_2661641_4 - - - - 0.000000000003836 74.0
TLS3_k127_2661641_5 Oxidoreductase - - - 0.00000000003265 66.0
TLS3_k127_2661641_6 Putative glycolipid-binding K09957 - - 0.000003911 50.0
TLS3_k127_2663931_0 Cytochrome c K08738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 359.0
TLS3_k127_2663931_10 regulation of response to stimulus K02396,K13735,K21449 - - 0.0000004844 61.0
TLS3_k127_2663931_11 COG1670 Acetyltransferases, including N-acetylases of - - - 0.00001123 50.0
TLS3_k127_2663931_12 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00002478 57.0
TLS3_k127_2663931_13 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0001267 49.0
TLS3_k127_2663931_2 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000191 239.0
TLS3_k127_2663931_3 polysaccharide catabolic process K01179,K01218 - 3.2.1.4,3.2.1.78 0.000000000000000000000000000000000000000000000000000000000000000008236 243.0
TLS3_k127_2663931_4 addiction module antidote protein HigA K07110,K21686 - - 0.0000000000000000000000000000000000000000003342 169.0
TLS3_k127_2663931_5 molybdopterin biosynthesis K03750 - 2.10.1.1 0.000000000000000000000000000000000000000001834 163.0
TLS3_k127_2663931_6 Domain of unknown function (DUF4112) - - - 0.0000000000000000000000000000000000009765 145.0
TLS3_k127_2663931_7 C-terminal domain of CHU protein family - - - 0.0000000000000000000000002587 125.0
TLS3_k127_2663931_8 intracellular protein transport K05989 - 3.2.1.40 0.0000000000000000000007515 113.0
TLS3_k127_2663931_9 Fn3 associated - - - 0.000000000125 76.0
TLS3_k127_2674907_0 Belongs to the heme-copper respiratory oxidase family K15862 - 1.9.3.1 2.066e-305 951.0
TLS3_k127_2674907_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K03778 - 1.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 409.0
TLS3_k127_2674907_2 cytochrome C oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 316.0
TLS3_k127_2674907_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000007267 288.0
TLS3_k127_2674907_4 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000001986 184.0
TLS3_k127_2674907_5 Cytochrome c K00406 - - 0.000000000000000000000000000000000001491 148.0
TLS3_k127_2674907_6 Cation transporter/ATPase, N-terminus K01537 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.8 0.000000000000000000000000000003892 124.0
TLS3_k127_2674907_7 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000002 88.0
TLS3_k127_2674907_8 Cytochrome oxidase maturation protein - - - 0.0001238 49.0
TLS3_k127_269031_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 3.331e-263 820.0
TLS3_k127_269031_1 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000002778 205.0
TLS3_k127_269031_2 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000002634 202.0
TLS3_k127_269031_3 cell redox homeostasis - - - 0.000000000000000000000000000000000000009919 153.0
TLS3_k127_2710513_0 Right handed beta helix region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 419.0
TLS3_k127_2710513_1 Belongs to the glycosyl hydrolase 30 family K18579 - 3.2.1.164 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000975 409.0
TLS3_k127_2710513_10 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000001187 189.0
TLS3_k127_2710513_11 acetyltransferase - - - 0.0000000000000000000000000000000000000000000007487 171.0
TLS3_k127_2710513_12 membrane organization - - - 0.0000000000000000000000000000000000000000000009337 187.0
TLS3_k127_2710513_13 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000803 168.0
TLS3_k127_2710513_14 protein trimerization K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000008452 187.0
TLS3_k127_2710513_15 antisigma factor binding K04749,K20978 - - 0.00000000000000000000000000000000000000003885 154.0
TLS3_k127_2710513_16 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000005621 153.0
TLS3_k127_2710513_18 Dockerin type I repeat - - - 0.000000000000000000000000000000000374 143.0
TLS3_k127_2710513_19 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000001893 134.0
TLS3_k127_2710513_2 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 354.0
TLS3_k127_2710513_20 peptidyl-prolyl cis-trans isomerase activity K03771 - 5.2.1.8 0.000000000000000000000000000000005486 149.0
TLS3_k127_2710513_21 Acid phosphatase homologues - - - 0.000000000000000000000000000004352 132.0
TLS3_k127_2710513_22 - - - - 0.00000000000000000000000000003379 124.0
TLS3_k127_2710513_23 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.0000000000000000000001342 114.0
TLS3_k127_2710513_24 membrane K03748 - - 0.00000000000000000002542 100.0
TLS3_k127_2710513_25 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000003421 101.0
TLS3_k127_2710513_26 FlhB HrpN YscU SpaS Family K04061 - - 0.000000000000000001093 89.0
TLS3_k127_2710513_28 UPF0391 membrane protein - - - 0.0000000000000002448 80.0
TLS3_k127_2710513_3 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 341.0
TLS3_k127_2710513_30 COG NOG27188 non supervised orthologous group - - - 0.000000000008705 73.0
TLS3_k127_2710513_31 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000271 60.0
TLS3_k127_2710513_32 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.0000009008 63.0
TLS3_k127_2710513_4 CBD_II K01179,K03933 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006571 281.0
TLS3_k127_2710513_5 Lytic polysaccharide mono-oxygenase, cellulose-degrading K03933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000915 278.0
TLS3_k127_2710513_6 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000764 269.0
TLS3_k127_2710513_7 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000003736 246.0
TLS3_k127_2710513_8 lipid kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000009426 226.0
TLS3_k127_2710513_9 Carbohydrate esterase, sialic acid-specific acetylesterase - - - 0.000000000000000000000000000000000000000000000000000002513 203.0
TLS3_k127_2726697_0 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 464.0
TLS3_k127_2726697_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 377.0
TLS3_k127_2726697_2 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 353.0
TLS3_k127_2726697_3 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000005188 234.0
TLS3_k127_2726697_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000001277 212.0
TLS3_k127_2726697_5 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000577 192.0
TLS3_k127_2726697_6 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000447 186.0
TLS3_k127_2726697_7 ROK family - - - 0.0000000006684 64.0
TLS3_k127_2726697_8 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.0000001288 54.0
TLS3_k127_2726697_9 Lamin Tail Domain - - - 0.00000035 63.0
TLS3_k127_2745233_0 PFAM aminotransferase, class I K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004888 428.0
TLS3_k127_2745233_1 coproporphyrinogen oxidase activity K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 359.0
TLS3_k127_2745233_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 320.0
TLS3_k127_2745233_3 cob(I)yrinic acid a,c-diamide adenosyltransferase activity K00798,K13821 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 0.0000000000000000000000000000000000000000000000000006839 197.0
TLS3_k127_2745233_4 nUDIX hydrolase K03575,K13797 - 2.7.7.6 0.000000000000000000000000004093 124.0
TLS3_k127_2745233_5 Histidine kinase - - - 0.00000000000000002629 94.0
TLS3_k127_2745233_6 Polyketide cyclase dehydrase - - - 0.00008125 51.0
TLS3_k127_2745233_7 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K13566 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050152,GO:0071944,GO:0106008 3.5.1.3 0.0007843 43.0
TLS3_k127_2751639_0 AAA domain (dynein-related subfamily) K07452 - - 1.048e-279 877.0
TLS3_k127_2751639_1 McrBC 5-methylcytosine restriction system component K19147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 418.0
TLS3_k127_2751639_2 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000000000002554 192.0
TLS3_k127_2751639_3 arylamine N-acetyltransferase activity - - - 0.000000000000000000113 99.0
TLS3_k127_2751639_4 ORF6N domain - - - 0.0000000001766 65.0
TLS3_k127_2751639_5 ORF6N domain - - - 0.00000008825 55.0
TLS3_k127_2751639_6 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0071944 - 0.00000948 50.0
TLS3_k127_2787959_0 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001395 284.0
TLS3_k127_2787959_1 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000008394 205.0
TLS3_k127_2787959_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000004085 151.0
TLS3_k127_2787959_3 Glycosyl transferases group 1 - - - 0.00000000000000000000004737 110.0
TLS3_k127_2787959_4 - - - - 0.00000007897 64.0
TLS3_k127_2787959_5 - - - - 0.0000007023 60.0
TLS3_k127_2787959_6 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.0007022 50.0
TLS3_k127_2790087_0 alpha-L-arabinofuranosidase - - - 1.933e-256 812.0
TLS3_k127_2790087_1 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 330.0
TLS3_k127_2790087_10 Right handed beta helix region - - - 0.000000000267 73.0
TLS3_k127_2790087_13 Protein tyrosine kinase - - - 0.000638 53.0
TLS3_k127_2790087_2 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001292 273.0
TLS3_k127_2790087_4 Serine hydrolase K07002 - - 0.0000000000000000000000000000000000000000000000000001426 192.0
TLS3_k127_2790087_5 - - - - 0.0000000000000000000000000000000000000000000000000001813 194.0
TLS3_k127_2790087_6 regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000001033 174.0
TLS3_k127_2790087_7 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.00000000000000000000000000000000002064 153.0
TLS3_k127_2790087_8 RNase H K06993 - - 0.000000000000000000000000000000006556 136.0
TLS3_k127_2790087_9 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000001007 108.0
TLS3_k127_2793198_0 protein conserved in bacteria - - - 0.0 1311.0
TLS3_k127_2793198_1 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 597.0
TLS3_k127_2793198_2 Cobalamin synthesis protein cobW C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 492.0
TLS3_k127_2793198_3 Domain of unknown function (DUF4194) - - - 0.000000000000000000000000000000000000000000000000000000000000000000007298 239.0
TLS3_k127_2793198_4 Integral membrane protein (intg_mem_TP0381) - - - 0.00000000000000000000000000000000000000000000000000309 189.0
TLS3_k127_2793198_5 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000001142 145.0
TLS3_k127_2793198_6 Uncharacterized protein conserved in bacteria N-term (DUF3322) - - - 0.00000023 55.0
TLS3_k127_2793198_7 - - - - 0.000000387 59.0
TLS3_k127_2800035_0 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000378 190.0
TLS3_k127_2800035_1 Fic/DOC family - - - 0.00000000000000000000000000000000000000000000175 177.0
TLS3_k127_2800035_2 proteolysis - - - 0.000000000000000000000000000000000003391 148.0
TLS3_k127_2800035_3 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000001205 117.0
TLS3_k127_2800035_4 Mobile mystery protein A - - - 0.00000000000000000000003002 111.0
TLS3_k127_2800035_5 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000000000000005261 92.0
TLS3_k127_2800035_6 TIGRFAM competence protein ComEA K02237 - - 0.000000000003142 76.0
TLS3_k127_2823730_0 CBD_II K01179 - 3.2.1.4 1.843e-262 828.0
TLS3_k127_2823730_1 Cellulase (glycosyl hydrolase family 5) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 443.0
TLS3_k127_2823730_2 Trehalose utilisation K09992 - - 0.00000000000000000000000000000000000000000000000000000014 216.0
TLS3_k127_2823730_3 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000007145 147.0
TLS3_k127_2823730_4 - - - - 0.000000000764 66.0
TLS3_k127_2823730_5 - - - - 0.000003125 57.0
TLS3_k127_2832474_0 phosphoenolpyruvate carboxylase activity K01595 - 4.1.1.31 1.726e-252 814.0
TLS3_k127_2832474_1 PFAM Major facilitator superfamily MFS-1 - - - 1.057e-205 646.0
TLS3_k127_2832474_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000002834 112.0
TLS3_k127_2832474_11 - - - - 0.000000001878 70.0
TLS3_k127_2832474_2 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 4.143e-204 643.0
TLS3_k127_2832474_3 PFAM ABC transporter related K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 329.0
TLS3_k127_2832474_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 316.0
TLS3_k127_2832474_5 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 289.0
TLS3_k127_2832474_6 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007779 289.0
TLS3_k127_2832474_7 Protein of unknown function (DUF2914) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000222 279.0
TLS3_k127_2832474_8 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000003787 220.0
TLS3_k127_2832474_9 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000002408 205.0
TLS3_k127_2833120_0 Oxygen tolerance - - - 0.0000000000000000000000000000000000000000000000003326 197.0
TLS3_k127_2833120_1 Bacterial SH3 domain homologues - - - 0.00000000000000002098 97.0
TLS3_k127_2833120_2 Tetratricopeptide repeat protein - - - 0.0001924 52.0
TLS3_k127_2841957_0 Domain of unknown function (DUF4301) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 451.0
TLS3_k127_2841957_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 293.0
TLS3_k127_2841957_10 Prokaryotic N-terminal methylation motif K02456,K02650,K02655 - - 0.000000001659 64.0
TLS3_k127_2841957_11 PFAM O-antigen polymerase - - - 0.00009265 55.0
TLS3_k127_2841957_2 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000002007 252.0
TLS3_k127_2841957_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000004906 188.0
TLS3_k127_2841957_4 Glycosyl hydrolase family 26 - - - 0.00000000000000000000000000000000000000005158 167.0
TLS3_k127_2841957_5 PFAM S1 P1 nuclease - - - 0.00000000000000000000000000000000000004295 160.0
TLS3_k127_2841957_6 DeoR C terminal sensor domain - - - 0.00000000000000000000000000007267 119.0
TLS3_k127_2841957_7 methyltransferase - - - 0.0000000000000000000000000003222 123.0
TLS3_k127_2841957_8 Prokaryotic N-terminal methylation motif K02456,K02650 - - 0.000000000001374 74.0
TLS3_k127_2841957_9 peptidyl-tyrosine sulfation - - - 0.0000000003184 71.0
TLS3_k127_285872_0 winged helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 574.0
TLS3_k127_285872_1 C-methyltransferase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 572.0
TLS3_k127_285872_10 G-rich domain on putative tyrosine kinase K16554 - - 0.0000000000000000000000000009445 131.0
TLS3_k127_285872_11 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000002728 108.0
TLS3_k127_285872_12 Tetratricopeptide repeat - - - 0.000000000000000000000008468 117.0
TLS3_k127_285872_14 transmembrane protein EpsH - - - 0.000001693 57.0
TLS3_k127_285872_2 Domains REC, sigma54 interaction, HTH8 K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 381.0
TLS3_k127_285872_3 Nucleotidyl transferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 361.0
TLS3_k127_285872_4 RmlD substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 290.0
TLS3_k127_285872_5 PFAM GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000108 267.0
TLS3_k127_285872_6 PEP-CTERM motif - - - 0.0000000000000000000000000000000000000000000000000001198 196.0
TLS3_k127_285872_7 Histidine kinase - - - 0.000000000000000000000000000000000000000000000006709 195.0
TLS3_k127_285872_8 Tautomerase enzyme - - - 0.000000000000000000000000000000000002414 142.0
TLS3_k127_285872_9 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000001461 146.0
TLS3_k127_2908999_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 3.404e-261 821.0
TLS3_k127_2908999_1 Outer membrane usher protein K07347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 322.0
TLS3_k127_2908999_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001254 265.0
TLS3_k127_2908999_3 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000000009299 222.0
TLS3_k127_2908999_4 Pili and flagellar-assembly chaperone, PapD N-terminal domain K07346 - - 0.000000000000000000002958 106.0
TLS3_k127_2912225_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 320.0
TLS3_k127_2912225_1 Carbohydrate esterase, sialic acid-specific acetylesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000665 294.0
TLS3_k127_2912225_10 Belongs to the glycosyl hydrolase 43 family K01218,K19551 - 3.2.1.78,4.2.2.10,4.2.2.2 0.0002214 49.0
TLS3_k127_2912225_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000002507 173.0
TLS3_k127_2912225_3 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000001478 170.0
TLS3_k127_2912225_4 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000003447 135.0
TLS3_k127_2912225_5 PA14 domain - - - 0.000000000000000000000003618 118.0
TLS3_k127_2912225_6 gluconolactonase K01053 - 3.1.1.17 0.00000000000000000000004129 112.0
TLS3_k127_2912225_7 PA14 - - - 0.0000000000000005597 92.0
TLS3_k127_2912225_8 lipolytic protein G-D-S-L family K00077 - 1.1.1.169 0.00000000000001243 87.0
TLS3_k127_2912225_9 pilus assembly protein PilW K01342,K02672,K20276 - 3.4.21.62 0.000007936 57.0
TLS3_k127_2934543_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 314.0
TLS3_k127_2934543_1 Bacterial protein of unknown function (DUF898) - - - 0.000000000000000000000000000000000000000000000001415 186.0
TLS3_k127_2934543_2 OPT oligopeptide transporter protein - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.00000000000000000000000000000000002232 140.0
TLS3_k127_2934543_3 Peptidase family M48 - - - 0.000000000000000000000000008331 123.0
TLS3_k127_2951990_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 614.0
TLS3_k127_2951990_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 432.0
TLS3_k127_2951990_2 Methyl-accepting chemotaxis protein (MCP) signaling domain K02660,K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 323.0
TLS3_k127_2951990_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000911 308.0
TLS3_k127_2951990_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001164 278.0
TLS3_k127_2951990_5 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001324 278.0
TLS3_k127_2951990_6 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000003717 130.0
TLS3_k127_2951990_7 Chemotaxis signal transduction protein K03408 - - 0.000000000000000000000000002545 117.0
TLS3_k127_2951990_8 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000004526 54.0
TLS3_k127_2953047_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 598.0
TLS3_k127_2953047_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008365 256.0
TLS3_k127_2953047_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000428 230.0
TLS3_k127_2953047_4 PFAM Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000006391 119.0
TLS3_k127_2953047_6 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.000000000000000000000004086 109.0
TLS3_k127_2953047_7 Glucose / Sorbosone dehydrogenase K08738 - - 0.000000000000002641 87.0
TLS3_k127_2953047_8 - - - - 0.00000000000379 72.0
TLS3_k127_2956262_0 Family membership - - - 0.0 1339.0
TLS3_k127_2956262_1 cellulase activity K20276 - - 1.824e-220 741.0
TLS3_k127_2956262_2 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 391.0
TLS3_k127_2956262_3 - - - - 0.000000000000000000003896 101.0
TLS3_k127_2956262_4 Domain of Unknown Function (DUF1080) - - - 0.00000004229 66.0
TLS3_k127_2956262_5 Purple acid Phosphatase, N-terminal domain - - - 0.0000001292 64.0
TLS3_k127_2958492_0 PFAM ABC transporter related K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008736 355.0
TLS3_k127_2958492_1 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000001133 229.0
TLS3_k127_2958492_2 Nucleoside-binding outer membrane protein - - - 0.000000000000000000000000005964 128.0
TLS3_k127_2967160_0 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 344.0
TLS3_k127_2967160_1 PFAM Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008022 291.0
TLS3_k127_2967160_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000002 252.0
TLS3_k127_2967160_3 oxidoreductase activity - - - 0.0000000000000000000000000000000000000004294 161.0
TLS3_k127_2967160_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000005137 140.0
TLS3_k127_2967160_5 Protein of unknown function (DUF971) K03593 - - 0.0000000000000000000000003362 112.0
TLS3_k127_2967160_7 protein tyrosine kinase activity K03593 - - 0.00006212 48.0
TLS3_k127_2980062_0 Histidine kinase A domain protein K03407 - 2.7.13.3 1.339e-212 687.0
TLS3_k127_2980062_1 Purple acid Phosphatase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 404.0
TLS3_k127_2980062_10 Glycosyl hydrolases family 6 K01179 - 3.2.1.4 0.000000000000007605 89.0
TLS3_k127_2980062_11 PIN domain K18828 - - 0.00000000000007322 76.0
TLS3_k127_2980062_12 Trehalose utilisation K09992 - - 0.00000004097 65.0
TLS3_k127_2980062_2 Glycoside hydrolase family 44 K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 391.0
TLS3_k127_2980062_3 Belongs to the glycosyl hydrolase 43 family K01181 GO:0003674,GO:0003824,GO:0004553,GO:0016787,GO:0016798,GO:0031176,GO:0033905,GO:0097599 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000007238 276.0
TLS3_k127_2980062_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001884 250.0
TLS3_k127_2980062_5 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000002756 254.0
TLS3_k127_2980062_6 GAF domain - - - 0.000000000000000000000000000000000000000000000000003996 203.0
TLS3_k127_2980062_7 GAF domain - - - 0.00000000000000000000000000000000000000000000003309 173.0
TLS3_k127_2980062_8 Ca-dependent carbohydrate-binding module xylan-binding - - - 0.000000000000000000000000000000000000000000205 172.0
TLS3_k127_2980062_9 Response regulator, receiver - - - 0.000000000000000000000008383 109.0
TLS3_k127_298445_0 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 1.762e-305 951.0
TLS3_k127_298445_1 KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 540.0
TLS3_k127_298445_10 TIGRFAM nitrate ABC transporter, ATPase subunits C and D K15578 - - 0.0000000000000000000000000000000008248 134.0
TLS3_k127_298445_11 Protein of unknown function, DUF480 K09915 - - 0.000000000000000000000000000000002832 145.0
TLS3_k127_298445_12 Paraquat-inducible protein A - - - 0.00000000000000000000000001172 125.0
TLS3_k127_298445_13 member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins - GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050308 - 0.000000000000000006863 94.0
TLS3_k127_298445_14 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000004091 84.0
TLS3_k127_298445_15 Protein of unknown function (DUF2847) - - - 0.00000000000249 72.0
TLS3_k127_298445_16 Alginate export - - - 0.00000000002811 76.0
TLS3_k127_298445_17 Acetyltransferase (GNAT) domain - - - 0.00000008365 66.0
TLS3_k127_298445_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005131 398.0
TLS3_k127_298445_3 Binding-protein-dependent transport system inner membrane component K02050,K15577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 339.0
TLS3_k127_298445_4 NMT1-like family K15576 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 317.0
TLS3_k127_298445_5 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 302.0
TLS3_k127_298445_6 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000001626 246.0
TLS3_k127_298445_7 Nitrate transport ATP-binding subunits C and D K11953,K15579 - - 0.000000000000000000000000000000000000000000000000003665 185.0
TLS3_k127_298445_8 OsmC-like protein K04063 - - 0.0000000000000000000000000000000000000007964 153.0
TLS3_k127_298445_9 DTW K05812 - - 0.00000000000000000000000000000000000008684 152.0
TLS3_k127_2986428_0 amidase activity K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 591.0
TLS3_k127_2986428_1 tRNA pseudouridine synthase activity K06173 GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000001842 237.0
TLS3_k127_2986428_2 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000002182 246.0
TLS3_k127_2986428_4 NlpC/P60 family K13695 - - 0.0000002711 62.0
TLS3_k127_2993894_0 Methylglyoxal synthase K01734 - 4.2.3.3 0.00000000000000000000000000000000000000000000000000000003571 199.0
TLS3_k127_2993894_1 SprA-related family - - - 0.0000000000000000000000000005205 117.0
TLS3_k127_2993894_2 protein conserved in bacteria - - - 0.0000000000000000000000003539 115.0
TLS3_k127_2993894_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000002671 77.0
TLS3_k127_3002407_0 Common central domain of tyrosinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 513.0
TLS3_k127_3002407_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 472.0
TLS3_k127_3002407_10 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000004455 144.0
TLS3_k127_3002407_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000005956 141.0
TLS3_k127_3002407_12 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000004019 144.0
TLS3_k127_3002407_13 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000001039 128.0
TLS3_k127_3002407_14 DNA-binding transcription factor activity - - - 0.0000000000000000000000001635 111.0
TLS3_k127_3002407_15 phage envelope protein - - - 0.0000000000000005364 80.0
TLS3_k127_3002407_16 Protein of unknown function (DUF3303) - - - 0.00000000000002105 75.0
TLS3_k127_3002407_17 Protein of unknown function (DUF3185) - - - 0.000000000007807 69.0
TLS3_k127_3002407_18 NB-ARC domain - - - 0.0000001168 62.0
TLS3_k127_3002407_19 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0003437 49.0
TLS3_k127_3002407_2 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 488.0
TLS3_k127_3002407_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 412.0
TLS3_k127_3002407_4 PFAM Integral membrane protein TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 394.0
TLS3_k127_3002407_5 peptidase activity K01467 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 331.0
TLS3_k127_3002407_6 Belongs to the UDP-glycosyltransferase family K14596 - 2.4.1.276 0.00000000000000000000000000000000000000000000000000000000000000004538 240.0
TLS3_k127_3002407_7 PFAM bifunctional deaminase-reductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000008006 199.0
TLS3_k127_3002407_8 FG-GAP repeat protein - - - 0.00000000000000000000000000000000000000000002598 186.0
TLS3_k127_3002407_9 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000000000000000000001612 149.0
TLS3_k127_3052651_0 PA14 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 328.0
TLS3_k127_3052651_1 Belongs to the glycosyl hydrolase 43 family K06113 - 3.2.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 309.0
TLS3_k127_3052651_2 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005904 264.0
TLS3_k127_3052651_3 Trehalose utilization protein K09992 - - 0.000000000005022 78.0
TLS3_k127_3052651_4 phospholipase Carboxylesterase - - - 0.0000000004134 72.0
TLS3_k127_3086711_0 GTPase activity K03596 - - 8.712e-228 715.0
TLS3_k127_3086711_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000002113 222.0
TLS3_k127_3086711_2 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000001515 231.0
TLS3_k127_3097048_0 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005943 280.0
TLS3_k127_3097048_1 WHG domain - - - 0.00000000000000000000000000004835 124.0
TLS3_k127_3097048_2 Pilus assembly protein PilX - - - 0.00000000000000005015 96.0
TLS3_k127_3097771_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 583.0
TLS3_k127_3097771_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 482.0
TLS3_k127_3097771_11 Belongs to the SpoVG family K06412 - - 0.0004981 44.0
TLS3_k127_3097771_2 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008337 431.0
TLS3_k127_3097771_3 Sensor histidine kinase PilS, PAS domain-containing K02668,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000009771 189.0
TLS3_k127_3097771_4 Recombinase K06400 - - 0.000000000000000000000000000003721 136.0
TLS3_k127_3097771_5 cell redox homeostasis K02199 - - 0.00000000000000000000000001531 115.0
TLS3_k127_3097771_6 - - - - 0.000000000000000000000006759 104.0
TLS3_k127_3097771_7 Mu-like prophage FluMu protein gp28 - - - 0.000000000000000000446 102.0
TLS3_k127_3097771_8 Belongs to the anti-sigma-factor antagonist family - - - 0.00000000000349 71.0
TLS3_k127_3097771_9 Belongs to the SpoVG family K06412 - - 0.000000006388 61.0
TLS3_k127_3112753_0 KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 548.0
TLS3_k127_3112753_1 ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 417.0
TLS3_k127_3112753_2 Belongs to the UPF0502 family K09915 - - 0.0000000000000000000000000000000008698 141.0
TLS3_k127_3112753_3 Paraquat-inducible protein A - - - 0.000000000000000000000000000000002942 135.0
TLS3_k127_3112753_4 tigr02147 - - - 0.00000000000000000000003563 110.0
TLS3_k127_3112753_5 Haloacid dehalogenase domain protein hydrolase, type 3 - - - 0.000000000000000002161 97.0
TLS3_k127_3112753_6 belongs to the thioredoxin family - - - 0.0000000000009715 73.0
TLS3_k127_3112753_7 PFAM OsmC family protein K04063 - - 0.00000001835 55.0
TLS3_k127_3176338_0 Periplasmic copper-binding protein (NosD) K07218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 372.0
TLS3_k127_3176338_1 lipoprotein involved in nitrous oxide reduction K19342 - - 0.000000000000000000000000000000000000000000000000000000001125 218.0
TLS3_k127_3176338_2 PFAM Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.000000000000000000000000000000000000000000000000000001834 193.0
TLS3_k127_3187468_0 Lactoylglutathione lyase K02028,K07032 - 3.6.3.21 0.0000000000000000000000000000000000000000000001208 172.0
TLS3_k127_3187468_1 membrane-associated protein K03975 - - 0.0000000000000000000000000000000000001466 157.0
TLS3_k127_3187468_2 Protein of unknown function (DUF3392) - - - 0.000001262 55.0
TLS3_k127_3202196_0 von Willebrand factor (vWF) type A domain K07114,K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 332.0
TLS3_k127_3202196_1 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 332.0
TLS3_k127_3202196_2 cytochrome complex assembly K02198,K02200,K04016,K04017,K04018 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564 - 0.0000000000000000000000007304 119.0
TLS3_k127_3208895_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0 1314.0
TLS3_k127_3208895_1 Metal-dependent hydrolase K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000958 248.0
TLS3_k127_3268461_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 3.5e-323 1013.0
TLS3_k127_3268461_1 6-phosphofructokinase activity K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 4.551e-218 689.0
TLS3_k127_3268461_10 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000002957 198.0
TLS3_k127_3268461_11 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000006577 160.0
TLS3_k127_3268461_12 Bacterial Ig-like domain - - - 0.00000000000000000000000000000000000004044 150.0
TLS3_k127_3268461_13 Rhodanese Homology Domain - - - 0.0000000000000000000000000189 116.0
TLS3_k127_3268461_14 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0000000000000000000001725 98.0
TLS3_k127_3268461_15 Bacterial Ig-like domain - - - 0.000000000000000003103 85.0
TLS3_k127_3268461_16 - - - - 0.000000000000002219 83.0
TLS3_k127_3268461_17 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000002145 76.0
TLS3_k127_3268461_2 Oxygenase, catalysing oxidative methylation of damaged DNA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 553.0
TLS3_k127_3268461_20 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.000000004873 57.0
TLS3_k127_3268461_21 ZIP Zinc transporter K07238 GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005384,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015086,GO:0015087,GO:0015093,GO:0015318,GO:0015684,GO:0015691,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0034755,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070574,GO:0070838,GO:0071421,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903874 - 0.0000003744 57.0
TLS3_k127_3268461_3 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 495.0
TLS3_k127_3268461_4 L-lactate permease K03303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 350.0
TLS3_k127_3268461_5 LysM domain K08307,K12204 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008978 352.0
TLS3_k127_3268461_6 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 320.0
TLS3_k127_3268461_7 Glycosyl hydrolase family 10 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 310.0
TLS3_k127_3268461_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004802 248.0
TLS3_k127_3268461_9 signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000005378 213.0
TLS3_k127_3328795_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 336.0
TLS3_k127_3328795_1 Flagellar Motor Protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003242 249.0
TLS3_k127_3328795_10 DNA-sulfur modification-associated - - - 0.0000003261 62.0
TLS3_k127_3328795_11 Glyoxalase-like domain - - - 0.0000003612 55.0
TLS3_k127_3328795_12 - - - - 0.0000006085 55.0
TLS3_k127_3328795_2 FliG C-terminal domain K02410 GO:0001539,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006928,GO:0006935,GO:0008150,GO:0009288,GO:0009605,GO:0009987,GO:0040011,GO:0042221,GO:0042330,GO:0042802,GO:0042803,GO:0042995,GO:0043226,GO:0043228,GO:0044403,GO:0044419,GO:0044464,GO:0046982,GO:0046983,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243,GO:0071973,GO:0071978,GO:0097588 - 0.0000000000000000000000000000000000000000000000000000000000000000001709 252.0
TLS3_k127_3328795_3 MotA/TolQ/ExbB proton channel family K02556 - - 0.000000000000000000000000000000000000000000000000000131 195.0
TLS3_k127_3328795_4 DNA methyltransferase K07443 - - 0.00000000000000000000000001856 112.0
TLS3_k127_3328795_5 MORN repeat variant - - - 0.000000000000000000008017 108.0
TLS3_k127_3328795_6 - - - - 0.000000000000004467 85.0
TLS3_k127_3328795_7 UPF0391 membrane protein - - - 0.0000000000001556 74.0
TLS3_k127_3358846_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000001166 262.0
TLS3_k127_3358846_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000001934 169.0
TLS3_k127_3358846_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000001964 152.0
TLS3_k127_336457_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 608.0
TLS3_k127_336457_1 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008511 569.0
TLS3_k127_336457_10 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 308.0
TLS3_k127_336457_11 Glycosyltransferase like family 2 K07011,K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006323 334.0
TLS3_k127_336457_12 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006111 293.0
TLS3_k127_336457_13 methyltransferase K02853,K12582 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008417,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0036065,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046378,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901576 2.4.1.325 0.00000000000000000000000000000000000000000000000000000000000000000000000001482 261.0
TLS3_k127_336457_14 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000343 254.0
TLS3_k127_336457_15 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001148 239.0
TLS3_k127_336457_16 Cytidylyltransferase K07257 - - 0.00000000000000000000000000000000000000000000000000000000000000007012 230.0
TLS3_k127_336457_17 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000003249 199.0
TLS3_k127_336457_18 PFAM glycosyl transferase family 9 - - - 0.0000000000000000000000000000000000000000000000000001212 198.0
TLS3_k127_336457_19 methyltransferase activity K00563,K02169 - 2.1.1.187,2.1.1.197 0.000000000000000000000000000000000000000000000585 174.0
TLS3_k127_336457_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 500.0
TLS3_k127_336457_20 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000007624 193.0
TLS3_k127_336457_21 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000911 168.0
TLS3_k127_336457_22 - - - - 0.000000000000000000000000000000000000002033 157.0
TLS3_k127_336457_23 PFAM Kelch - - - 0.000000000000000000000000000000000000007518 167.0
TLS3_k127_336457_24 Methyltransferase domain - - - 0.0000000000000000000000005549 114.0
TLS3_k127_336457_25 Kelch motif - - - 0.00000000000009827 78.0
TLS3_k127_336457_3 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 495.0
TLS3_k127_336457_4 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 482.0
TLS3_k127_336457_5 NeuB family K01654 - 2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000725 455.0
TLS3_k127_336457_6 Cytidylyltransferase K07257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 314.0
TLS3_k127_336457_7 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 311.0
TLS3_k127_336457_8 TIGRFAM pseudaminic acid biosynthesis-associated protein PseG K15897 - 3.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 311.0
TLS3_k127_336457_9 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 336.0
TLS3_k127_3385163_0 InterPro IPR010496 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003044 244.0
TLS3_k127_3385163_1 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000000000000000000000000000000000000002968 235.0
TLS3_k127_3385163_2 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.000000000000000000000000000000000000000000000000000000000000001197 228.0
TLS3_k127_3385163_3 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000000000000000000005715 202.0
TLS3_k127_3398089_0 unfolded protein binding - - - 4.312e-217 692.0
TLS3_k127_3398089_1 DNA-K related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 442.0
TLS3_k127_3398089_2 Domain of unknown function (DUF2760) - - - 0.0000000000000000000000000004797 127.0
TLS3_k127_3398089_3 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K19270 - 3.1.3.23 0.0000000000005512 72.0
TLS3_k127_3410661_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.027e-317 990.0
TLS3_k127_3410661_1 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000001047 184.0
TLS3_k127_3410661_2 mercury ion transmembrane transporter activity K07213,K08364 - - 0.0000000007297 64.0
TLS3_k127_3431225_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 392.0
TLS3_k127_3431225_1 extracellular solute-binding protein, family 5 K02035,K15584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 346.0
TLS3_k127_3431225_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000004579 136.0
TLS3_k127_3431225_3 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000001251 138.0
TLS3_k127_3447448_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 542.0
TLS3_k127_3447448_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000001637 240.0
TLS3_k127_3447448_2 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000005591 231.0
TLS3_k127_3447448_3 PFAM Chorismate mutase, type II - - - 0.00000000000000751 86.0
TLS3_k127_3462551_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 361.0
TLS3_k127_3462551_1 Peptidase, M16 K07263,K07623 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 347.0
TLS3_k127_3462551_2 Peptidase, M16 K07263 - - 0.00000000000004492 78.0
TLS3_k127_3473255_0 Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 327.0
TLS3_k127_3473255_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 330.0
TLS3_k127_3473255_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000001892 222.0
TLS3_k127_3473255_3 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000001746 207.0
TLS3_k127_3473255_4 Planctomycete cytochrome C - - - 0.0003927 49.0
TLS3_k127_3476688_0 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000001079 184.0
TLS3_k127_3476688_1 CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238 - - - 0.00000000000000000000000000002372 131.0
TLS3_k127_3476688_2 Preprotein translocase YajC subunit K03210 - - 0.0000000000002137 75.0
TLS3_k127_3481195_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 610.0
TLS3_k127_3481195_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 495.0
TLS3_k127_3481195_2 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 284.0
TLS3_k127_3481195_3 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000001186 179.0
TLS3_k127_3481195_4 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000001811 155.0
TLS3_k127_3481195_5 ABC transporter permease K02004 - - 0.00000000000000000000003364 115.0
TLS3_k127_3481195_6 Protein of unknown function (DUF465) K09794 - - 0.00000000000000000001689 95.0
TLS3_k127_3481195_7 - - - - 0.00000000000001348 87.0
TLS3_k127_3481195_8 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000007844 74.0
TLS3_k127_3487227_0 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 394.0
TLS3_k127_3487227_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 379.0
TLS3_k127_3487227_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 377.0
TLS3_k127_3487227_3 permease protein PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 376.0
TLS3_k127_3487227_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000007881 172.0
TLS3_k127_3487227_5 Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism K13998 GO:0003674,GO:0003824,GO:0004146,GO:0004799,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019752,GO:0032259,GO:0034641,GO:0042083,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.5.1.3,2.1.1.45 0.000000000000000000000000000001786 133.0
TLS3_k127_3498575_0 Glycogen debranching enzyme - - - 0.00000000000000000000000000005432 129.0
TLS3_k127_3498575_1 Tetratricopeptide repeat - - - 0.00006825 53.0
TLS3_k127_3510591_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 8.369e-196 614.0
TLS3_k127_3510591_1 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 388.0
TLS3_k127_3510591_2 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 342.0
TLS3_k127_3510591_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001488 233.0
TLS3_k127_3510591_6 Evidence 5 No homology to any previously reported sequences K07752 - 3.4.17.22 0.0000001025 63.0
TLS3_k127_3528677_0 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 299.0
TLS3_k127_3528677_1 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000000000000000000000000000000000000000000000001397 204.0
TLS3_k127_3528677_2 Hemerythrin hhe cation binding - - - 0.000000000000000000000000000000003378 136.0
TLS3_k127_3528677_3 Belongs to the ABC transporter superfamily K12372 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 - 0.0000000000000000000000001977 108.0
TLS3_k127_3528677_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000001833 111.0
TLS3_k127_3528677_5 - - - - 0.000000000002113 72.0
TLS3_k127_3557103_0 Baseplate J-like protein - - - 6.265e-275 874.0
TLS3_k127_3557103_1 Two component regulator propeller - - - 5.311e-242 775.0
TLS3_k127_3557103_2 cellulose binding - - - 8.853e-226 721.0
TLS3_k127_3557103_3 Baseplate J-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 537.0
TLS3_k127_3557103_4 Late control gene D protein - - - 0.00000000000000000000000000000000000000000000000000000000000002259 229.0
TLS3_k127_3557103_5 Gene 25-like lysozyme - - - 0.0000000000000000000000000000000000000000000004518 170.0
TLS3_k127_3557103_6 PFAM Phage-related baseplate assembly protein - - - 0.000000000000000000000000000000000000000000005873 178.0
TLS3_k127_3557103_7 - - - - 0.000000000000000000000000000002362 123.0
TLS3_k127_3561546_0 MmgE/PrpD family K01720 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0047547,GO:0071704 4.2.1.79 7.706e-200 635.0
TLS3_k127_3561546_1 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 565.0
TLS3_k127_3561546_10 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 307.0
TLS3_k127_3561546_11 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 299.0
TLS3_k127_3561546_12 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 295.0
TLS3_k127_3561546_13 Pyridine nucleotide-disulphide oxidoreductase K00362,K05297 - 1.18.1.1,1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001926 287.0
TLS3_k127_3561546_14 GSCFA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002747 276.0
TLS3_k127_3561546_15 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001374 262.0
TLS3_k127_3561546_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001329 242.0
TLS3_k127_3561546_17 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000004971 244.0
TLS3_k127_3561546_18 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000007285 196.0
TLS3_k127_3561546_19 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000001973 217.0
TLS3_k127_3561546_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 574.0
TLS3_k127_3561546_20 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000002257 190.0
TLS3_k127_3561546_21 cellulase activity - - - 0.00000000000000000000000000000000000000000000321 182.0
TLS3_k127_3561546_22 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000004262 164.0
TLS3_k127_3561546_23 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000008454 168.0
TLS3_k127_3561546_24 COG2148 Sugar transferases involved in lipopolysaccharide synthesis - - - 0.0000000000000000000000000000000000000008619 169.0
TLS3_k127_3561546_25 PFAM Integrase catalytic region - - - 0.000000000000000000000000000000001785 141.0
TLS3_k127_3561546_26 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000006039 125.0
TLS3_k127_3561546_27 Rubredoxin - - - 0.00000000000000000000000008765 107.0
TLS3_k127_3561546_28 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.000000000000000000003623 107.0
TLS3_k127_3561546_29 type IV pilus modification protein PilV - - - 0.000001148 60.0
TLS3_k127_3561546_3 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006015 537.0
TLS3_k127_3561546_32 Surface antigen variable number K07001 - - 0.000167 55.0
TLS3_k127_3561546_33 Tfp pilus assembly protein tip-associated adhesin PilY1 K02674 - - 0.0001918 54.0
TLS3_k127_3561546_34 type IV pilus modification protein PilV - - - 0.0008529 50.0
TLS3_k127_3561546_4 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972,K10754 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 498.0
TLS3_k127_3561546_5 Belongs to the citrate synthase family K01659 - 2.3.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 473.0
TLS3_k127_3561546_6 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 378.0
TLS3_k127_3561546_7 TIGRFAM Polyphosphate nucleotide phosphotransferase, PPK2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 370.0
TLS3_k127_3561546_8 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 378.0
TLS3_k127_3561546_9 NmrA family K19267 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 347.0
TLS3_k127_3599922_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006392 537.0
TLS3_k127_3599922_1 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001466 285.0
TLS3_k127_3599922_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000006046 126.0
TLS3_k127_3599922_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000004343 87.0
TLS3_k127_3599922_4 Domain of unknown function DUF302 - - - 0.0000000000000001955 89.0
TLS3_k127_3599922_5 Beta-lactamase - - - 0.0007364 48.0
TLS3_k127_3602224_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 503.0
TLS3_k127_3602224_1 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000001271 137.0
TLS3_k127_3602224_2 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071944 - 0.00000000000000000000000000000003813 125.0
TLS3_k127_3602224_3 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000216 123.0
TLS3_k127_3602224_4 Ribosomal protein L30p/L7e K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000005418 61.0
TLS3_k127_3602224_5 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000002124 53.0
TLS3_k127_3637415_0 permease - - - 0.000000000000000000000000000000000000000000000000000000001915 220.0
TLS3_k127_3637415_1 Belongs to the acetyltransferase family. ArgA subfamily K00619,K00930,K14682 GO:0003674,GO:0003824,GO:0003991,GO:0004042,GO:0004358,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.7.2.8 0.0000000000000000000000000000000000000000000000000001349 192.0
TLS3_k127_3637415_2 Protein of unknown function DUF72 - - - 0.00000000000000000000000001826 119.0
TLS3_k127_3637415_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000009564 86.0
TLS3_k127_363762_0 Type III restriction enzyme res subunit K10843 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 593.0
TLS3_k127_363762_1 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 344.0
TLS3_k127_363762_2 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002389 280.0
TLS3_k127_363762_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000002361 211.0
TLS3_k127_363762_4 Biotin/lipoate A/B protein ligase family K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000000000000000000000000000000000000002549 160.0
TLS3_k127_363762_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000001755 101.0
TLS3_k127_363762_6 Glycosyltransferase Family 4 - - - 0.00000000000000002261 96.0
TLS3_k127_3640820_0 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000001737 211.0
TLS3_k127_3640820_1 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000002573 191.0
TLS3_k127_3640820_2 - - - - 0.000000000000000000000000000000000001292 143.0
TLS3_k127_3640820_3 peptidase U32 K08303 - - 0.00000000000000000000000002271 111.0
TLS3_k127_3640820_4 - - - - 0.00000000002845 74.0
TLS3_k127_3646035_0 phosphorelay signal transduction system K07713,K07714,K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 431.0
TLS3_k127_3646035_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 399.0
TLS3_k127_3646035_10 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000285 155.0
TLS3_k127_3646035_11 Glycosyl transferase family 2 - - - 0.00000000000000000000000000001822 131.0
TLS3_k127_3646035_12 PFAM methyltransferase small - - - 0.000000000000005027 85.0
TLS3_k127_3646035_13 Glycosyltransferase like family 2 - - - 0.00000000000001252 86.0
TLS3_k127_3646035_2 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 353.0
TLS3_k127_3646035_3 Signal transduction histidine kinase, nitrogen specific, NtrB K07708,K07710,K10942 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 309.0
TLS3_k127_3646035_4 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 310.0
TLS3_k127_3646035_5 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000006751 276.0
TLS3_k127_3646035_6 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004253 269.0
TLS3_k127_3646035_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000006812 211.0
TLS3_k127_3646035_8 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000006601 180.0
TLS3_k127_3646035_9 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000004527 164.0
TLS3_k127_3669011_0 serine-type D-Ala-D-Ala carboxypeptidase activity K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 527.0
TLS3_k127_3669011_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 469.0
TLS3_k127_3669011_2 Cell division ATP-binding protein ftsE K09812 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008783 276.0
TLS3_k127_3669011_3 methyltransferase - - - 0.00000000000000000000000005671 112.0
TLS3_k127_3669011_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000007971 111.0
TLS3_k127_3669011_5 Belongs to the Fur family K03711 - - 0.00000000000000000000003458 108.0
TLS3_k127_3669011_6 Belongs to the UPF0145 family - - - 0.00000001261 66.0
TLS3_k127_3669011_7 rRNA binding K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000009448 51.0
TLS3_k127_3669011_8 PFAM Bacterial Ig-like domain (group 2) - - - 0.0000811 55.0
TLS3_k127_3730535_0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 589.0
TLS3_k127_3730535_1 glycosyl transferase K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 506.0
TLS3_k127_3730535_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000001894 209.0
TLS3_k127_3730535_3 - - - - 0.0000000000000000000000000001 122.0
TLS3_k127_3740103_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002504 263.0
TLS3_k127_3740103_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000005508 98.0
TLS3_k127_3740103_2 - - - - 0.00000001579 65.0
TLS3_k127_3742146_0 phosphoenolpyruvate carboxykinase (diphosphate) activity K20370 - 4.1.1.38 7.844e-232 739.0
TLS3_k127_3742146_1 Circularly permuted ATP-grasp type 2 - - - 6.439e-220 693.0
TLS3_k127_3742146_10 - K00712 - 2.4.1.52 0.00000000000000000000005145 115.0
TLS3_k127_3742146_11 Protein of unknown function (DUF3105) - - - 0.000000000000000000006363 104.0
TLS3_k127_3742146_12 PFAM AIG2 family protein K20757 - 4.3.1.27 0.0000000000000001234 87.0
TLS3_k127_3742146_13 ChrR Cupin-like domain - - - 0.0000000000006844 79.0
TLS3_k127_3742146_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 615.0
TLS3_k127_3742146_3 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 353.0
TLS3_k127_3742146_4 Phage late control gene D protein (GPD) K11904 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009089 292.0
TLS3_k127_3742146_5 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001276 271.0
TLS3_k127_3742146_6 protein conserved in bacteria K11904 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008467 258.0
TLS3_k127_3742146_7 Domain of unknown function (DUF4150) - - - 0.00000000000000000000000000000000000000000007354 180.0
TLS3_k127_3742146_8 synthase K00647 - 2.3.1.41 0.0000000000000000000000000000000000000121 161.0
TLS3_k127_3742146_9 COG3806 Anti-sigma factor - - - 0.000000000000000000000000000456 126.0
TLS3_k127_3751873_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 370.0
TLS3_k127_3751873_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000008452 181.0
TLS3_k127_3751873_2 AAA domain K01939 - 6.3.4.4 0.0000000000000000000000000001055 121.0
TLS3_k127_3761008_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 296.0
TLS3_k127_3761008_1 Rhodanese-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001201 260.0
TLS3_k127_3761008_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000565 137.0
TLS3_k127_3761008_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000007501 126.0
TLS3_k127_3761008_4 alpha amylase, catalytic K01187 - 3.2.1.20 0.00000009573 56.0
TLS3_k127_3767929_0 Mismatch repair ATPase (MutS family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009746 404.0
TLS3_k127_3767929_1 Phage late control gene D protein (GPD) K11904 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 372.0
TLS3_k127_3767929_2 hydrolase K07025 - - 0.0000000000000000000000000000000000009348 147.0
TLS3_k127_3767929_3 addiction module antidote protein HigA K07110,K21686 - - 0.00000000000000000000000000000001449 139.0
TLS3_k127_3767929_4 negative regulation of toll-like receptor 2 signaling pathway - - - 0.000000002425 70.0
TLS3_k127_3767929_5 Peptidoglycan-binding domain 1 protein K08640 - 3.4.17.14 0.00000001604 69.0
TLS3_k127_3767929_6 Belongs to the ompA family - - - 0.0001073 56.0
TLS3_k127_3767929_7 domain protein K20276 - - 0.0002169 54.0
TLS3_k127_377317_0 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 475.0
TLS3_k127_377317_1 N(6)-L-threonylcarbamoyladenine synthase activity K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 381.0
TLS3_k127_377317_2 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000006978 218.0
TLS3_k127_377317_3 Methyltransferase domain - - - 0.00000000000000000008321 102.0
TLS3_k127_377317_4 receptor - - - 0.000000000001605 81.0
TLS3_k127_379448_0 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001221 265.0
TLS3_k127_3809496_0 cobalamin binding K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1293.0
TLS3_k127_3809496_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 4.389e-272 852.0
TLS3_k127_3809496_10 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.000000000000000000000000000000000000000000000000000000000000000001922 235.0
TLS3_k127_3809496_11 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000007361 169.0
TLS3_k127_3809496_12 ferredoxin oxidoreductase K00169 - 1.2.7.1 0.00000000000000000000000000000000005332 156.0
TLS3_k127_3809496_13 - - - - 0.000000000000000000000000000003234 127.0
TLS3_k127_3809496_14 - - - - 0.000000000000000000000000003599 121.0
TLS3_k127_3809496_15 4Fe-4S binding domain - - - 0.00000000000000000000000006705 113.0
TLS3_k127_3809496_16 MotA TolQ ExbB proton channel family K03561 - - 0.0000000000000000000002045 105.0
TLS3_k127_3809496_17 ExbD TolR K03559 - - 0.000000000000000000004946 105.0
TLS3_k127_3809496_18 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000000009368 94.0
TLS3_k127_3809496_19 BEST Arabidopsis thaliana protein match is Cyclopropane-fatty-acyl-phospholipid synthase (TAIR K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0008825,GO:0009987,GO:0016740,GO:0016741,GO:0030258,GO:0032259,GO:0044237,GO:0044238,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704 2.1.1.79 0.000000000000009548 79.0
TLS3_k127_3809496_2 AIPR protein - - - 2.147e-231 727.0
TLS3_k127_3809496_20 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00172 - 1.2.7.1 0.0002158 55.0
TLS3_k127_3809496_21 TIGRFAM 2-oxoacid acceptor oxidoreductase, delta subunit, pyruvate 2-ketoisovalerate K00171,K00172 - 1.2.7.1 0.0002841 55.0
TLS3_k127_3809496_3 CoA carboxylase activity K01969,K13778,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4,6.4.1.5 1.169e-214 683.0
TLS3_k127_3809496_4 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 524.0
TLS3_k127_3809496_5 Acyclic terpene utilisation family protein AtuA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 482.0
TLS3_k127_3809496_6 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 337.0
TLS3_k127_3809496_7 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 304.0
TLS3_k127_3809496_8 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004375 279.0
TLS3_k127_3809496_9 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001075 271.0
TLS3_k127_3812956_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000004245 254.0
TLS3_k127_3812956_1 PFAM Blue (type 1) copper domain K09992 - - 0.000000000000000000000000000007768 128.0
TLS3_k127_3812956_2 Uncharacterised protein conserved in bacteria (DUF2313) - - - 0.000000000000000000000001164 111.0
TLS3_k127_3812956_3 signal transduction histidine kinase K13587 - 2.7.13.3 0.00000000000000000002746 96.0
TLS3_k127_3812956_4 Bacteriophage lambda head decoration protein D - - - 0.00000000000002522 87.0
TLS3_k127_3812956_6 Carboxypeptidase regulatory-like domain - - - 0.0001914 55.0
TLS3_k127_381840_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 581.0
TLS3_k127_381840_1 phenylalanine-tRNA ligase activity K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000001204 228.0
TLS3_k127_3827181_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 440.0
TLS3_k127_3827181_1 Polysaccharide export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 362.0
TLS3_k127_3827181_10 response regulator receiver K02481,K07713 - - 0.00000003048 61.0
TLS3_k127_3827181_11 transferase activity, transferring glycosyl groups - - - 0.0000005318 54.0
TLS3_k127_3827181_2 SAF K01654 - 2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000001284 263.0
TLS3_k127_3827181_3 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000104 187.0
TLS3_k127_3827181_4 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K19270 - 3.1.3.23 0.0000000000000000000000000000000000000000000004847 174.0
TLS3_k127_3827181_5 PFAM acylneuraminate cytidylyltransferase K00983 - 2.7.7.43 0.0000000000000000000000000000000000000000163 161.0
TLS3_k127_3827181_7 O-methyltransferase activity K15257,K20444 - - 0.0000000000000001189 88.0
TLS3_k127_3827181_8 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000008116 70.0
TLS3_k127_3827181_9 Cytidylyltransferase K00983,K18431 - 2.7.7.43,2.7.7.82 0.00000000353 58.0
TLS3_k127_3906446_0 arginine decarboxylase activity K01585 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008792,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009308,GO:0009309,GO:0009445,GO:0009446,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0034641,GO:0042401,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.1.1.19 8.492e-298 932.0
TLS3_k127_3906446_1 Glycoside hydrolase family 44 K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 439.0
TLS3_k127_3906446_2 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000000000000000001687 177.0
TLS3_k127_3906446_3 Cro/C1-type HTH DNA-binding domain K07727 - - 0.0000000000000000000000002227 106.0
TLS3_k127_3906446_4 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000326 108.0
TLS3_k127_3906446_5 amine dehydrogenase activity - - - 0.00000000000000002585 97.0
TLS3_k127_3906446_6 Protein of unknown function (DUF3175) - - - 0.00001304 49.0
TLS3_k127_3906446_7 - - - - 0.00003241 48.0
TLS3_k127_3906446_8 - - - - 0.0002458 47.0
TLS3_k127_3966736_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 526.0
TLS3_k127_3966736_1 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000415 271.0
TLS3_k127_3966736_2 addiction module antidote protein HigA K07110,K21686 - - 0.000000000000000000000000000000000000000000000004638 184.0
TLS3_k127_3966736_3 PA14 K08738 - - 0.00000000000000000000000000000004325 130.0
TLS3_k127_3966736_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000235 116.0
TLS3_k127_3966736_5 SMP-30 Gluconolaconase LRE-like K01053 - 3.1.1.17 0.000000000000000000001216 107.0
TLS3_k127_3966736_6 Glycosyl hydrolases family 16 - - - 0.000005935 59.0
TLS3_k127_3966736_7 Domain of Unknown Function (DUF1080) - - - 0.00003974 55.0
TLS3_k127_3985620_0 Disulphide bond corrector protein DsbC K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 609.0
TLS3_k127_3985620_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 316.0
TLS3_k127_3985620_2 Thermolysin metallopeptidase, catalytic domain K01400 - 3.4.24.28 0.000000000000000000000000000002102 136.0
TLS3_k127_3985620_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000001513 106.0
TLS3_k127_4008642_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000001569 240.0
TLS3_k127_4008642_1 ABC transporter related K16786,K16787 - - 0.000000000000000000000000000000000000000337 163.0
TLS3_k127_4008642_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000002219 126.0
TLS3_k127_4009715_0 Belongs to the heme-copper respiratory oxidase family K15862 - 1.9.3.1 2.586e-282 879.0
TLS3_k127_4009715_1 PFAM Cytochrome c, class I K00406 - - 0.000000000000000000000000000000000001052 146.0
TLS3_k127_4026288_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.000000000000000000000000000000000000000000000000000000002218 200.0
TLS3_k127_4026288_1 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000001502 172.0
TLS3_k127_4090526_0 ferredoxin-NADP+ reductase activity K00384,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 1.183e-211 683.0
TLS3_k127_4090526_1 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000001304 190.0
TLS3_k127_4090526_2 transmembrane protein 64-like - - - 0.00000000000000000001448 108.0
TLS3_k127_4090526_3 cellulose binding - - - 0.0000000001064 64.0
TLS3_k127_4091120_0 1,4-alpha-glucan branching enzyme activity K00700,K01187,K01236,K17734 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18,3.2.1.141,3.2.1.20 3.215e-270 851.0
TLS3_k127_4091120_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 7.295e-245 773.0
TLS3_k127_4091120_2 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000002295 157.0
TLS3_k127_4091120_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000002422 153.0
TLS3_k127_4091120_4 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000001956 158.0
TLS3_k127_4091120_6 protein trimerization K15368 - - 0.000000000000000000000000004351 119.0
TLS3_k127_4091120_7 - - - - 0.0000000000000000000000882 103.0
TLS3_k127_4091120_8 Two component regulator propeller K19693 - - 0.00000000000000000002028 106.0
TLS3_k127_4091120_9 Protein involved in outer membrane biogenesis - - - 0.0000001378 65.0
TLS3_k127_4191165_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817,K04720 - 2.6.1.9,4.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 323.0
TLS3_k127_4191165_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000001994 173.0
TLS3_k127_4191165_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000006196 166.0
TLS3_k127_4191165_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00002121 55.0
TLS3_k127_4206202_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003252 288.0
TLS3_k127_4206202_1 - - - - 0.000000000000000001972 93.0
TLS3_k127_4206202_2 Peptidase family C25 - - - 0.0002644 52.0
TLS3_k127_4232723_0 PFAM oxidoreductase - - - 6.801e-212 663.0
TLS3_k127_4232723_1 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 405.0
TLS3_k127_4232723_2 PFAM Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008348 254.0
TLS3_k127_4232723_3 FMN reductase (NADPH) activity K00299,K16902 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006790,GO:0006805,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008752,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009111,GO:0009267,GO:0009308,GO:0009310,GO:0009410,GO:0009605,GO:0009970,GO:0009987,GO:0009991,GO:0010181,GO:0016043,GO:0016054,GO:0016491,GO:0016645,GO:0016646,GO:0019439,GO:0019694,GO:0019752,GO:0022607,GO:0031667,GO:0031668,GO:0031669,GO:0032553,GO:0032787,GO:0033554,GO:0034641,GO:0036094,GO:0042178,GO:0042221,GO:0042365,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0042594,GO:0043167,GO:0043168,GO:0043420,GO:0043421,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046218,GO:0046306,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0052873,GO:0055114,GO:0065003,GO:0070887,GO:0071466,GO:0071496,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.5.1.38,1.5.1.45 0.00000000000000000000000000000000000000000000004304 175.0
TLS3_k127_4245464_0 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341,K05577 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 496.0
TLS3_k127_4245464_1 NAD binding K00333,K05579,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 445.0
TLS3_k127_4245464_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331,K05582 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 385.0
TLS3_k127_4245464_3 quinone binding K00337,K05572 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 366.0
TLS3_k127_4245464_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000009438 173.0
TLS3_k127_4245464_5 NADH dehydrogenase (ubiquinone) activity K00330,K05574 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000007627 123.0
TLS3_k127_4245464_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.0000000000000000009518 90.0
TLS3_k127_4245464_7 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000005216 82.0
TLS3_k127_4271743_0 Belongs to the DEAD box helicase family K05591 GO:0000027,GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033677,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 419.0
TLS3_k127_4271743_1 ATPase (AAA superfamily) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 402.0
TLS3_k127_4271743_2 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000000000009453 192.0
TLS3_k127_4271743_3 PFAM Restriction endonuclease, type I, EcoEI, R subunit Type III, Res subunit, C-terminal K01153 - 3.1.21.3 0.000000000000000000000000002267 111.0
TLS3_k127_4271743_4 Protein of unknown function (DUF2892) - - - 0.0000000000008209 72.0
TLS3_k127_4284936_0 Cell division ATP-binding protein ftsE K09812 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001355 270.0
TLS3_k127_4284936_1 peptidyl-prolyl cis-trans isomerase activity K03769,K03771,K07533 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000002769 252.0
TLS3_k127_4284936_2 methyltransferase - - - 0.00000000000000000000000000000000000555 147.0
TLS3_k127_4284936_3 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.0000008612 61.0
TLS3_k127_4284936_4 Belongs to the UPF0145 family - - - 0.000002064 59.0
TLS3_k127_4318682_0 PFAM response regulator receiver K11384 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 542.0
TLS3_k127_4318682_1 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 373.0
TLS3_k127_4318682_2 COGs COG2220 Zn-dependent hydrolase of the beta-lactamase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 362.0
TLS3_k127_4318682_3 virion core protein (lumpy skin disease virus) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 346.0
TLS3_k127_4318682_4 Transcription factor zinc-finger - - - 0.0000000000000000000000000000000000000002619 163.0
TLS3_k127_4318682_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11383 - 2.7.13.3 0.00000003029 60.0
TLS3_k127_4365677_0 PKD domain - - - 3.251e-198 651.0
TLS3_k127_4365677_1 COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 524.0
TLS3_k127_4365677_10 Sigma-70 region 3 K03086 - - 0.0000000000000000000000000000000000000000000000000000000001122 214.0
TLS3_k127_4365677_11 PFAM SEC-C motif K09858 - - 0.00000000000000000000000000000000000000000000000000006803 191.0
TLS3_k127_4365677_12 Histidine kinase - - - 0.000000000000000000000000000000000000000001391 163.0
TLS3_k127_4365677_13 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000002243 133.0
TLS3_k127_4365677_14 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.000000000000000000000000000009213 123.0
TLS3_k127_4365677_15 - - - - 0.0000000000000000000000003072 119.0
TLS3_k127_4365677_16 PFAM Rhomboid family - - - 0.0000000000000000000008577 109.0
TLS3_k127_4365677_17 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000004096 89.0
TLS3_k127_4365677_18 PFAM Integrase catalytic region - - - 0.000000000000000009045 95.0
TLS3_k127_4365677_19 - - - - 0.00000000000001533 76.0
TLS3_k127_4365677_2 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 502.0
TLS3_k127_4365677_20 Two component regulator propeller - - - 0.0000000000001019 79.0
TLS3_k127_4365677_21 Domain of Unknown Function (DUF1521) - - - 0.0003459 53.0
TLS3_k127_4365677_3 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 477.0
TLS3_k127_4365677_4 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0016874,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 469.0
TLS3_k127_4365677_5 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 417.0
TLS3_k127_4365677_6 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 376.0
TLS3_k127_4365677_7 PFAM HTH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 325.0
TLS3_k127_4365677_8 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 304.0
TLS3_k127_4365677_9 flavin adenine dinucleotide binding - - - 0.000000000000000000000000000000000000000000000000000000000000142 229.0
TLS3_k127_4383969_0 metallopeptidase activity K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 339.0
TLS3_k127_4383969_1 Alpha-2-Macroglobulin K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 331.0
TLS3_k127_4383969_2 Roadblock/LC7 domain - - - 0.00000000000000000000000000000002335 131.0
TLS3_k127_4383969_3 Mitochondrial biogenesis AIM24 - - - 0.000004918 58.0
TLS3_k127_438467_0 5TM C-terminal transporter carbon starvation CstA - - - 0.0000000000000000000000000000000000000000000000000000000001126 205.0
TLS3_k127_438467_1 - - - - 0.000000000000000000000000000002175 135.0
TLS3_k127_438467_2 SnoaL-like domain K06893 - - 0.00000000000001098 83.0
TLS3_k127_4386736_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 297.0
TLS3_k127_4386736_1 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000002086 244.0
TLS3_k127_4386736_2 - K01992 - - 0.000000000000000000000000000000000129 151.0
TLS3_k127_4386736_3 Domain of unknown function (DUF4340) - - - 0.0000002726 62.0
TLS3_k127_4425566_0 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000001115 237.0
TLS3_k127_4425566_1 xylanase chitin deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000002113 236.0
TLS3_k127_4425566_2 Sugar transferase - - - 0.0000000000000000000000000000000000000000001765 181.0
TLS3_k127_4425566_3 - - - - 0.00000000000000000000002016 110.0
TLS3_k127_4425566_4 MORN repeat variant - - - 0.0000002445 60.0
TLS3_k127_4425566_5 - - - - 0.0000005456 59.0
TLS3_k127_4438223_0 dehydrogenase e1 component K00164 - 1.2.4.2 0.0 1167.0
TLS3_k127_4438223_1 Aconitase C-terminal domain K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 444.0
TLS3_k127_4438223_2 OmpA family - - - 0.0000000000000000000004993 106.0
TLS3_k127_4438223_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000008118 97.0
TLS3_k127_4438223_4 Belongs to the ompA family - - - 0.0000000000000000007622 101.0
TLS3_k127_4467160_0 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 424.0
TLS3_k127_4467160_1 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 387.0
TLS3_k127_4467160_2 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005073 268.0
TLS3_k127_4467160_3 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000004217 193.0
TLS3_k127_4467160_4 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000002095 169.0
TLS3_k127_4467160_5 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000004412 171.0
TLS3_k127_4467160_6 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000005809 108.0
TLS3_k127_4482100_0 - - - - 1e-323 1008.0
TLS3_k127_4482100_1 Protein of unknown function (DUF1360) - - - 0.0000000000000000000000001867 113.0
TLS3_k127_4482100_2 ATPase (AAA superfamily K07133 - - 0.000000000000000000000000219 118.0
TLS3_k127_44885_0 Belongs to the aspartokinase family K12524,K12525 GO:0003674,GO:0003824,GO:0004072,GO:0004412,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009090,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 496.0
TLS3_k127_44885_1 Mismatch repair ATPase (MutS family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 414.0
TLS3_k127_44885_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481,K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004749 260.0
TLS3_k127_44885_3 COG0608 Single-stranded DNA-specific exonuclease - - - 0.00000000000000000000000000000000000000000000000000000000004162 218.0
TLS3_k127_44885_4 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000004776 194.0
TLS3_k127_44885_5 Squalene--hopene cyclase - - - 0.0000000000000000000000000000001553 130.0
TLS3_k127_44885_6 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.00000000000000000000000001642 121.0
TLS3_k127_4491212_0 nuclear chromosome segregation K03529,K19171 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 558.0
TLS3_k127_4491212_1 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 368.0
TLS3_k127_4491212_2 Domains HisKA, HATPase_c - - - 0.000000000000000000000000000358 129.0
TLS3_k127_4491212_3 Esterase PHB depolymerase K03932 - - 0.000000003334 67.0
TLS3_k127_4505689_0 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 295.0
TLS3_k127_4505689_1 FAE1/Type III polyketide synthase-like protein - - - 0.000000384 58.0
TLS3_k127_4505689_2 translation release factor activity K02835 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016149,GO:0019538,GO:0019866,GO:0022411,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032543,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070126,GO:0071704,GO:0071840,GO:0097159,GO:0140053,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000001984 53.0
TLS3_k127_4560135_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 3.842e-278 897.0
TLS3_k127_4560135_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 301.0
TLS3_k127_4560135_2 NmrA family - - - 0.00000000000000000000000000000000000000000000000000000000002264 216.0
TLS3_k127_4560135_3 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000002978 190.0
TLS3_k127_4560135_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930,K14682 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.7.2.8 0.0000000000000000000000000000000000000000000000000006976 194.0
TLS3_k127_4560135_6 electron transfer activity K05337 - - 0.00000000000000005005 82.0
TLS3_k127_4560135_7 Periplasmic copper-binding protein (NosD) - - - 0.0000005253 62.0
TLS3_k127_4593450_0 Histidine kinase A domain protein K03407 - 2.7.13.3 0.0 1243.0
TLS3_k127_4593450_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 7.409e-224 713.0
TLS3_k127_4593450_10 CotH kinase protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 340.0
TLS3_k127_4593450_11 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817,K04720 - 2.6.1.9,4.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007068 331.0
TLS3_k127_4593450_12 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 314.0
TLS3_k127_4593450_13 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 297.0
TLS3_k127_4593450_14 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 308.0
TLS3_k127_4593450_15 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 292.0
TLS3_k127_4593450_16 Methylenetetrahydrofolate reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 292.0
TLS3_k127_4593450_17 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001734 300.0
TLS3_k127_4593450_18 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002128 295.0
TLS3_k127_4593450_19 phospholipase Carboxylesterase K18286 - 3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000006107 269.0
TLS3_k127_4593450_2 acetolactate synthase K01652 - 2.2.1.6 2.268e-218 695.0
TLS3_k127_4593450_20 Domain of unknown function (DUF4956) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009116 263.0
TLS3_k127_4593450_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002399 265.0
TLS3_k127_4593450_22 VTC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008091 253.0
TLS3_k127_4593450_23 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003233 246.0
TLS3_k127_4593450_24 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000002929 242.0
TLS3_k127_4593450_25 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA - - - 0.00000000000000000000000000000000000000000000000000000000000000001257 228.0
TLS3_k127_4593450_26 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000007893 235.0
TLS3_k127_4593450_27 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000001477 218.0
TLS3_k127_4593450_28 SMART chemotaxis sensory transducer K03406,K13487 - - 0.0000000000000000000000000000000000000000000000000000000005758 219.0
TLS3_k127_4593450_29 TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000000000000000000000000000000000000001584 222.0
TLS3_k127_4593450_3 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 555.0
TLS3_k127_4593450_30 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000006397 201.0
TLS3_k127_4593450_31 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000000000000000000000003903 184.0
TLS3_k127_4593450_32 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000000000000000001766 180.0
TLS3_k127_4593450_33 Transcriptional regulator K02019 - - 0.0000000000000000000000000000000000000000000000001997 187.0
TLS3_k127_4593450_34 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000002665 171.0
TLS3_k127_4593450_36 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000006293 131.0
TLS3_k127_4593450_37 xylan catabolic process K03932 - - 0.0000000000000000000000000000004484 123.0
TLS3_k127_4593450_39 CHAD - - - 0.0000000000000000000002578 110.0
TLS3_k127_4593450_4 UDP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 509.0
TLS3_k127_4593450_40 - - - - 0.00000000000000003421 87.0
TLS3_k127_4593450_41 Associated with various cellular activities K04748 - - 0.0000000000000001539 90.0
TLS3_k127_4593450_42 protein adenylyltransferase activity K17277 GO:0000166,GO:0003008,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005783,GO:0005789,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006836,GO:0006950,GO:0006952,GO:0007600,GO:0007601,GO:0007610,GO:0007632,GO:0008081,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009581,GO:0009582,GO:0009583,GO:0009584,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009966,GO:0009987,GO:0010646,GO:0012505,GO:0015696,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0017076,GO:0018117,GO:0018175,GO:0019538,GO:0023051,GO:0030176,GO:0030544,GO:0030554,GO:0031072,GO:0031224,GO:0031227,GO:0031967,GO:0031975,GO:0031984,GO:0032501,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034260,GO:0034976,GO:0035639,GO:0036094,GO:0036211,GO:0042175,GO:0042578,GO:0042742,GO:0042802,GO:0042803,GO:0043086,GO:0043087,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044601,GO:0044602,GO:0044603,GO:0045117,GO:0046983,GO:0048519,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050829,GO:0050877,GO:0050896,GO:0050906,GO:0050908,GO:0050953,GO:0050962,GO:0051087,GO:0051179,GO:0051234,GO:0051336,GO:0051346,GO:0051606,GO:0051608,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0065009,GO:0070566,GO:0070733,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0080134,GO:0080135,GO:0097159,GO:0097367,GO:0098542,GO:0098827,GO:0140096,GO:1900101,GO:1901265,GO:1901363,GO:1901564,GO:1903894,GO:1905897 - 0.000000000001662 79.0
TLS3_k127_4593450_44 Histidine kinase-like ATPases - - - 0.0000355 51.0
TLS3_k127_4593450_45 Outer membrane receptor K02014 - - 0.00008037 53.0
TLS3_k127_4593450_46 transporter - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0002274 44.0
TLS3_k127_4593450_5 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 512.0
TLS3_k127_4593450_6 Rhodanase C-terminal K07146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 466.0
TLS3_k127_4593450_7 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 434.0
TLS3_k127_4593450_8 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 432.0
TLS3_k127_4593450_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 411.0
TLS3_k127_459363_0 Nitrite and sulphite reductase 4Fe-4S domain K00392 - 1.8.7.1 6.218e-208 659.0
TLS3_k127_459363_1 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000005791 176.0
TLS3_k127_4624423_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 297.0
TLS3_k127_4624423_1 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000005349 243.0
TLS3_k127_4624423_2 - K01992 - - 0.000000000000000000000000000000007955 145.0
TLS3_k127_4628728_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 348.0
TLS3_k127_4628728_1 FG-GAP repeat - - - 0.0000000000000000000000000000000000000000000000000000000000144 233.0
TLS3_k127_4628728_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000005455 211.0
TLS3_k127_4628728_3 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000002541 126.0
TLS3_k127_4628728_4 COG0515 Serine threonine protein - - - 0.000000000000002528 90.0
TLS3_k127_4628728_5 Protein conserved in bacteria - - - 0.000000000008341 68.0
TLS3_k127_4628728_6 amine dehydrogenase activity - - - 0.000004256 59.0
TLS3_k127_4628728_7 PFAM glycoside hydrolase clan GH-D K07407 - 3.2.1.22 0.00002468 57.0
TLS3_k127_4631340_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 461.0
TLS3_k127_4631340_1 bacterial-type flagellum-dependent cell motility K02388,K02390,K02396,K03418,K07004,K15125,K21012 - 3.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 362.0
TLS3_k127_4631340_2 Ricin-type beta-trefoil - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004826 253.0
TLS3_k127_4631340_3 PFAM Rhomboid family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000151 239.0
TLS3_k127_4631340_4 Belongs to the bacterial flagellin family K02397 - - 0.000000000000000000000000000004768 133.0
TLS3_k127_4631340_5 DinB superfamily - - - 0.0000000000000001873 88.0
TLS3_k127_4634796_1 bacteriocin transport K03561 - - 0.00000000002059 77.0
TLS3_k127_4634796_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.000002608 61.0
TLS3_k127_4661137_0 TonB dependent receptor - - - 1.308e-210 687.0
TLS3_k127_4661137_1 COG0475 Kef-type K transport systems, membrane components K11745 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 574.0
TLS3_k127_4661137_10 InterPro IPR001584 COGs COG2801 - - - 0.00000000002747 72.0
TLS3_k127_4661137_11 biopolymer transport protein K03559,K03560 - - 0.0000000005485 66.0
TLS3_k127_4661137_12 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.000000006452 66.0
TLS3_k127_4661137_2 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 388.0
TLS3_k127_4661137_3 Alpha/beta hydrolase family K19707 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 295.0
TLS3_k127_4661137_4 Flavodoxin-like fold K03923,K11748 - - 0.000000000000000000000000000000000000000000000000000000000000000001477 232.0
TLS3_k127_4661137_5 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000006223 226.0
TLS3_k127_4661137_6 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000000000000003251 187.0
TLS3_k127_4661137_7 pathogenesis K06972,K18195 - 4.2.2.23 0.0000000000000000000000000001084 130.0
TLS3_k127_4661137_8 NnrS protein K07234 - - 0.0000000000000000000000005563 118.0
TLS3_k127_4661137_9 MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000007917 105.0
TLS3_k127_4665943_0 Iron-containing alcohol dehydrogenase K00001,K00100 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 441.0
TLS3_k127_4665943_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000003799 255.0
TLS3_k127_4665943_2 guanylate kinase activity K00942,K01591 GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000001846 218.0
TLS3_k127_4665943_3 tRNA processing K06864 - - 0.000000000000000000000000000000000000000000000000000000000001387 220.0
TLS3_k127_4665943_4 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000000000000000003941 202.0
TLS3_k127_4665943_5 addiction module antidote protein HigA K07110,K21686 - - 0.0000000000000000000000000000000000000005674 159.0
TLS3_k127_4674399_0 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000001745 177.0
TLS3_k127_4674399_1 Domain of unknown function (DUF4856) - - - 0.0000000000000000000000000000000000188 143.0
TLS3_k127_4674399_10 cellulose binding - - - 0.0003807 53.0
TLS3_k127_4674399_2 PA14 domain - - - 0.000000000000000000000000000004571 138.0
TLS3_k127_4674399_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000001198 107.0
TLS3_k127_4674399_5 lysyltransferase activity K07027 - - 0.00000000006643 74.0
TLS3_k127_4674399_6 Leucine-rich repeats, typical (most populated) subfamily K19613 - - 0.000007689 53.0
TLS3_k127_4674399_7 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00001082 53.0
TLS3_k127_4674399_8 cellulose binding - - - 0.00004161 57.0
TLS3_k127_4674399_9 PKD domain - - - 0.0001101 54.0
TLS3_k127_471303_0 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 417.0
TLS3_k127_471303_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 396.0
TLS3_k127_471303_10 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000001962 141.0
TLS3_k127_471303_12 Leucine rich repeat - - - 0.0000000000000000000000004801 121.0
TLS3_k127_471303_14 DNA-directed DNA polymerase K02346 - 2.7.7.7 0.0000000000000000000000111 115.0
TLS3_k127_471303_16 Leucine-rich repeat-containing protein K16175 GO:0000003,GO:0000122,GO:0000578,GO:0000902,GO:0001654,GO:0001655,GO:0001700,GO:0001708,GO:0001736,GO:0001737,GO:0001738,GO:0001745,GO:0001751,GO:0001752,GO:0001754,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002164,GO:0002165,GO:0002168,GO:0003002,GO:0003006,GO:0003008,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005911,GO:0005912,GO:0005918,GO:0005938,GO:0006355,GO:0006357,GO:0006810,GO:0007028,GO:0007043,GO:0007163,GO:0007164,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007308,GO:0007309,GO:0007314,GO:0007315,GO:0007318,GO:0007350,GO:0007351,GO:0007389,GO:0007391,GO:0007399,GO:0007423,GO:0007444,GO:0007464,GO:0007472,GO:0007476,GO:0007552,GO:0007560,GO:0007610,GO:0007611,GO:0007613,GO:0007635,GO:0008104,GO:0008150,GO:0008283,GO:0008285,GO:0008358,GO:0008544,GO:0008593,GO:0008595,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009798,GO:0009880,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009913,GO:0009948,GO:0009952,GO:0009966,GO:0009987,GO:0009994,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010646,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0016323,GO:0016327,GO:0016328,GO:0016331,GO:0016332,GO:0016333,GO:0016334,GO:0016335,GO:0016336,GO:0019219,GO:0019222,GO:0019953,GO:0019991,GO:0021700,GO:0022008,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0030010,GO:0030011,GO:0030029,GO:0030030,GO:0030054,GO:0030100,GO:0030154,GO:0030182,GO:0030707,GO:0030714,GO:0030855,GO:0030859,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031594,GO:0032501,GO:0032502,GO:0032504,GO:0032879,GO:0032989,GO:0033036,GO:0033043,GO:0034329,GO:0034330,GO:0034332,GO:0034333,GO:0035088,GO:0035089,GO:0035090,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035282,GO:0035295,GO:0035315,GO:0035316,GO:0035317,GO:0040008,GO:0042048,GO:0042058,GO:0042067,GO:0042127,GO:0042221,GO:0042706,GO:0042886,GO:0043296,GO:0043297,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044703,GO:0045108,GO:0045165,GO:0045169,GO:0045175,GO:0045178,GO:0045184,GO:0045186,GO:0045197,GO:0045198,GO:0045199,GO:0045202,GO:0045216,GO:0045570,GO:0045571,GO:0045892,GO:0045926,GO:0045934,GO:0046425,GO:0046530,GO:0046552,GO:0046620,GO:0046621,GO:0048056,GO:0048468,GO:0048469,GO:0048477,GO:0048513,GO:0048519,GO:0048523,GO:0048546,GO:0048557,GO:0048562,GO:0048563,GO:0048565,GO:0048566,GO:0048568,GO:0048569,GO:0048583,GO:0048592,GO:0048598,GO:0048599,GO:0048609,GO:0048638,GO:0048640,GO:0048663,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048749,GO:0048856,GO:0048863,GO:0048869,GO:0050678,GO:0050680,GO:0050789,GO:0050793,GO:0050794,GO:0050803,GO:0050877,GO:0050890,GO:0050896,GO:0051049,GO:0051093,GO:0051128,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051239,GO:0051241,GO:0051252,GO:0051253,GO:0051493,GO:0051704,GO:0051726,GO:0055123,GO:0060255,GO:0060429,GO:0060562,GO:0060581,GO:0060627,GO:0061162,GO:0061245,GO:0061326,GO:0061339,GO:0065007,GO:0065008,GO:0070160,GO:0070161,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072001,GO:0072002,GO:0072089,GO:0080090,GO:0090162,GO:0090596,GO:0097574,GO:0098590,GO:0099568,GO:0120036,GO:1901184,GO:1902531,GO:1902679,GO:1903506,GO:1903507,GO:1904892,GO:1990794,GO:2000026,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000001648 101.0
TLS3_k127_471303_17 PFAM Chemotaxis methyl-accepting receptor, signalling - - - 0.0000000000000003164 82.0
TLS3_k127_471303_18 aminotransferase class I and II - - - 0.000000000000003496 86.0
TLS3_k127_471303_19 Ankyrin repeats (many copies) - - - 0.00000000000439 73.0
TLS3_k127_471303_2 Protein of unknown function (DUF1348) K09958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004063 248.0
TLS3_k127_471303_20 hydrolase activity, acting on ester bonds - - - 0.00000002276 66.0
TLS3_k127_471303_21 Haemolytic - - - 0.000001661 55.0
TLS3_k127_471303_22 - - - - 0.0001291 46.0
TLS3_k127_471303_3 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000006774 210.0
TLS3_k127_471303_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000002245 215.0
TLS3_k127_471303_5 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000001868 188.0
TLS3_k127_471303_6 FMN reductase (NADPH) activity - - - 0.000000000000000000000000000000000000000000004188 169.0
TLS3_k127_471303_7 tigr02147 - - - 0.0000000000000000000000000000000000001128 153.0
TLS3_k127_471303_8 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000001441 144.0
TLS3_k127_471303_9 Domain of unknown function (DUF4123) - - - 0.00000000000000000000000000000000004765 140.0
TLS3_k127_4756919_0 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 609.0
TLS3_k127_4756919_1 MBOAT, membrane-bound O-acyltransferase family K19294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 474.0
TLS3_k127_4756919_10 - - - - 0.000000000000000000000000000002368 134.0
TLS3_k127_4756919_11 Domain of Unknown Function (DUF326) - - - 0.000000000000000000000000003609 117.0
TLS3_k127_4756919_12 Pfam:DUF303 - - - 0.000000000000006312 87.0
TLS3_k127_4756919_13 Transcription elongation factor - - - 0.00000000000001304 80.0
TLS3_k127_4756919_14 alpha/beta hydrolase fold - - - 0.00000294 51.0
TLS3_k127_4756919_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 366.0
TLS3_k127_4756919_3 Involved in the tonB-independent uptake of proteins - GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019586,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046397,GO:0071704,GO:0072329,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 329.0
TLS3_k127_4756919_4 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004063 289.0
TLS3_k127_4756919_5 SGNH hydrolase-like domain, acetyltransferase AlgX K19295 - - 0.00000000000000000000000000000000000000000000000000000000000000002084 238.0
TLS3_k127_4756919_6 Protein of unknown function (DUF3494) - - - 0.000000000000000000000000000000000000000000001105 178.0
TLS3_k127_4756919_7 Surface antigen - - - 0.0000000000000000000000000000000000000000008072 171.0
TLS3_k127_4756919_8 Bacterial transcriptional repressor - - - 0.0000000000000000000000000000000001276 140.0
TLS3_k127_4756919_9 - - - - 0.000000000000000000000000000000009904 136.0
TLS3_k127_4764003_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 1.523e-224 708.0
TLS3_k127_4764003_1 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 539.0
TLS3_k127_4764003_2 Transporter DASS family - - - 0.00000000000000000000000000000000000001821 155.0
TLS3_k127_4764797_0 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006513 552.0
TLS3_k127_4764797_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 377.0
TLS3_k127_4764797_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 331.0
TLS3_k127_4764797_3 inositol monophosphate 1-phosphatase activity K01092,K05602 - 3.1.3.15,3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000001855 270.0
TLS3_k127_4764797_4 Calcineurin-like phosphoesterase K07099 - - 0.000000000000000000000000000000000000000000000000000000000000541 219.0
TLS3_k127_4764797_5 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000007649 60.0
TLS3_k127_4793180_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.256e-200 643.0
TLS3_k127_4793180_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 346.0
TLS3_k127_4793180_2 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006311 310.0
TLS3_k127_4793180_3 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000356 219.0
TLS3_k127_4793180_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K00556,K03218,K03437 - 2.1.1.185,2.1.1.34 0.00000000000000000000000000000000000000000000000000007146 205.0
TLS3_k127_4793180_5 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000002838 158.0
TLS3_k127_4793180_6 CoA binding domain K06929 - - 0.0000000000000000001051 94.0
TLS3_k127_4793180_7 haloacid dehalogenase-like hydrolase - - - 0.000000000003317 79.0
TLS3_k127_4793180_8 - - - - 0.000004083 57.0
TLS3_k127_4797712_0 phosphorelay signal transduction system K07713,K07714,K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 421.0
TLS3_k127_4797712_1 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000006601 180.0
TLS3_k127_4797712_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000004527 164.0
TLS3_k127_4797712_3 Forkhead associated domain - - - 0.000009994 58.0
TLS3_k127_4803781_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01740 - 2.5.1.48,2.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009479 548.0
TLS3_k127_4803781_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 453.0
TLS3_k127_4803781_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 331.0
TLS3_k127_4803781_3 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000001746 249.0
TLS3_k127_4803781_4 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000002543 235.0
TLS3_k127_4803781_5 Fructosamine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000004209 234.0
TLS3_k127_4803781_6 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000158 175.0
TLS3_k127_4803781_7 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000004351 153.0
TLS3_k127_4803781_8 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000007995 106.0
TLS3_k127_4805754_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 1.652e-247 782.0
TLS3_k127_4805754_1 phosphoglucomutase activity K01835 GO:0000271,GO:0003674,GO:0003824,GO:0004614,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005996,GO:0006006,GO:0006012,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0016868,GO:0019318,GO:0019320,GO:0019388,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0055114,GO:0071704,GO:1901575,GO:1901576 5.4.2.2 1.553e-199 640.0
TLS3_k127_4805754_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 465.0
TLS3_k127_4805754_3 GNaT family - - - 0.000000000000000000000000000000000000000000000002166 178.0
TLS3_k127_4805754_4 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000005419 125.0
TLS3_k127_4805754_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000237 108.0
TLS3_k127_4819229_0 Belongs to the ABC transporter superfamily K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 304.0
TLS3_k127_4819229_1 glycerophosphodiester transmembrane transport K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009876 286.0
TLS3_k127_4819229_2 RNA pseudouridylate synthase K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000007544 248.0
TLS3_k127_4819229_3 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000004239 151.0
TLS3_k127_4839982_0 type I restriction-modification system K03427 - 2.1.1.72 0.0 1213.0
TLS3_k127_4839982_1 Protein of unknown function (DUF1016) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 465.0
TLS3_k127_4839982_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 451.0
TLS3_k127_4839982_3 Glycosyl transferases group 1 K13668 - 2.4.1.346 0.000000000000000000000000000000000000000000000000000000000000001081 233.0
TLS3_k127_4839982_4 Glycosyl transferases group 1 K13668 - 2.4.1.346 0.000000000000000000000000000000000000000000000000001027 197.0
TLS3_k127_4839982_5 MazG nucleotide pyrophosphohydrolase domain protein - - - 0.0000000000000000000000000000000000000000000000001078 180.0
TLS3_k127_4839982_6 membrane organization K07277 - - 0.0000000000000000000000000000000000000000007768 176.0
TLS3_k127_4839982_7 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.000000000000000000000000001354 120.0
TLS3_k127_4839982_8 Polysaccharide biosynthesis protein - - - 0.00000000000000000002734 105.0
TLS3_k127_4839982_9 methyltransferase - - - 0.0000000008915 68.0
TLS3_k127_4847711_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 4.954e-288 898.0
TLS3_k127_4847711_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 1.942e-255 798.0
TLS3_k127_4847711_2 Amino acid permease - - - 9.651e-233 739.0
TLS3_k127_4847711_3 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 576.0
TLS3_k127_4847711_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11383 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 474.0
TLS3_k127_4847711_5 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000008141 217.0
TLS3_k127_486025_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 521.0
TLS3_k127_486025_1 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 314.0
TLS3_k127_486025_2 4'-phosphopantetheinyl transferase superfamily - - - 0.000000000000000000002371 99.0
TLS3_k127_4890230_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 3.303e-279 870.0
TLS3_k127_4890230_1 Allophanate hydrolase K01457 - 3.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 591.0
TLS3_k127_4890230_10 NMT1/THI5 like - - - 0.00000000000000000000000000000000000000000000000000000589 195.0
TLS3_k127_4890230_11 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000008795 209.0
TLS3_k127_4890230_12 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000007115 166.0
TLS3_k127_4890230_13 PFAM secretion protein HlyD family protein K01993 - - 0.00000000000000000000000000000000000006337 157.0
TLS3_k127_4890230_14 - - - - 0.000000000000000000000000286 114.0
TLS3_k127_4890230_15 transcriptional regulator K09017 - - 0.0000000000000000000000003089 116.0
TLS3_k127_4890230_16 Reprolysin (M12B) family zinc metalloprotease - - - 0.000000000000000000000002708 120.0
TLS3_k127_4890230_17 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000008023 87.0
TLS3_k127_4890230_18 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000001168 81.0
TLS3_k127_4890230_19 DinB superfamily - - - 0.0000000001331 68.0
TLS3_k127_4890230_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 302.0
TLS3_k127_4890230_20 outer membrane efflux protein K03287 - - 0.00000001214 68.0
TLS3_k127_4890230_3 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 302.0
TLS3_k127_4890230_4 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 291.0
TLS3_k127_4890230_5 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000013 280.0
TLS3_k127_4890230_6 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006055 291.0
TLS3_k127_4890230_7 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008992 261.0
TLS3_k127_4890230_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002217 250.0
TLS3_k127_4890230_9 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000001417 212.0
TLS3_k127_4943420_0 histidine-tRNA ligase activity K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 431.0
TLS3_k127_4943420_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000007858 147.0
TLS3_k127_4943420_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000004683 93.0
TLS3_k127_4943420_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00001903 49.0
TLS3_k127_4962838_0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 287.0
TLS3_k127_4962838_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000005528 185.0
TLS3_k127_4962838_2 cobalamin-transporting ATPase activity K02014 - - 0.00000000000000000003517 97.0
TLS3_k127_4962838_3 Divergent polysaccharide deacetylase K09798 - - 0.000000000004356 79.0
TLS3_k127_4962838_4 - - - - 0.0003245 43.0
TLS3_k127_4963932_0 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000002764 138.0
TLS3_k127_4963932_1 domain, Protein - - - 0.0000000006552 74.0
TLS3_k127_4963932_2 LysM domain - - - 0.000001178 60.0
TLS3_k127_4963932_3 PFAM MORN repeat variant - - - 0.000001771 59.0
TLS3_k127_4963932_4 Bacterial Ig-like domain 2 - - - 0.000001911 62.0
TLS3_k127_4963932_5 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0008576 48.0
TLS3_k127_4973024_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 1.025e-250 784.0
TLS3_k127_4973024_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 537.0
TLS3_k127_4973024_10 PFAM Preprotein translocase SecG subunit K03075 - - 0.000003436 55.0
TLS3_k127_4973024_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 520.0
TLS3_k127_4973024_3 Aminotransferase K00812,K10907 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 387.0
TLS3_k127_4973024_4 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 360.0
TLS3_k127_4973024_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 322.0
TLS3_k127_4973024_6 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000006088 214.0
TLS3_k127_4973024_7 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000004242 197.0
TLS3_k127_4973024_8 Lytic transglycosylase catalytic K08307 - - 0.000000000000000000000000000000003703 146.0
TLS3_k127_4973024_9 PFAM Forkhead-associated protein - - - 0.0000002006 64.0
TLS3_k127_4975622_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 6.73e-274 878.0
TLS3_k127_4975622_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009593 512.0
TLS3_k127_4975622_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 385.0
TLS3_k127_4975622_3 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 383.0
TLS3_k127_4975622_4 lipoprotein localization to outer membrane K02004,K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 308.0
TLS3_k127_4975622_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01663,K02500 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003141 280.0
TLS3_k127_4975622_6 glutamine metabolic process K02501 - - 0.0000000000000000000000000000000000000000000000000000000000009856 217.0
TLS3_k127_4991123_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000008884 174.0
TLS3_k127_4991254_0 PA14 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 363.0
TLS3_k127_4991254_1 PFAM glycoside hydrolase, family 10 K01181 - 3.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 319.0
TLS3_k127_4991254_2 Glucose / Sorbosone dehydrogenase K08738 - - 0.000000000000000000000000000000000000000000000000000000000002718 221.0
TLS3_k127_4991254_3 Mycoplasma protein of unknown function, DUF285 - - - 0.0000000000000000000004325 114.0
TLS3_k127_4991254_4 PFAM PKD domain containing protein - - - 0.00000000000000002623 98.0
TLS3_k127_500793_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 472.0
TLS3_k127_500793_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 310.0
TLS3_k127_500793_2 Pfam:DUF303 K05970 - 3.1.1.53 0.0000000000000000000000000000000000000000000000000000000000000000003432 243.0
TLS3_k127_500793_3 HsdM N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000006925 189.0
TLS3_k127_500793_4 Virulence protein RhuM family - - - 0.000000000000000000000000000009013 123.0
TLS3_k127_5034243_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 2.508e-277 895.0
TLS3_k127_5034243_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 491.0
TLS3_k127_5034243_10 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K18827 - 2.1.1.222,2.1.1.294,2.1.1.64,2.7.1.181 0.000000000000000000000000003294 127.0
TLS3_k127_5034243_11 - - - - 0.00000000000000000000002128 108.0
TLS3_k127_5034243_12 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000008274 98.0
TLS3_k127_5034243_13 Protein of unknown function (DUF465) K09794 - - 0.000000000000000004379 88.0
TLS3_k127_5034243_2 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 435.0
TLS3_k127_5034243_3 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 376.0
TLS3_k127_5034243_4 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000002615 213.0
TLS3_k127_5034243_5 response regulator K07782 - - 0.000000000000000000000000000000000000000000001612 176.0
TLS3_k127_5034243_6 Belongs to the peptidase S51 family K05995 - 3.4.13.21 0.000000000000000000000000000000000000000003064 166.0
TLS3_k127_5034243_7 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000001017 154.0
TLS3_k127_5034243_8 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000001018 147.0
TLS3_k127_5034243_9 Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000002125 136.0
TLS3_k127_503619_0 addiction module antidote protein HigA K07110,K21686 - - 0.00000000000000000000000000000000000000000001648 172.0
TLS3_k127_503619_1 addiction module antidote protein HigA K07110,K21686 - - 0.0000000000000000000000000000000009155 142.0
TLS3_k127_503619_2 Fn3 associated - - - 0.000000000000000001305 99.0
TLS3_k127_5042822_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 358.0
TLS3_k127_5042822_1 ATP-dependent DNA helicase activity K00655,K03656,K03657,K05939 - 2.3.1.40,2.3.1.51,3.6.4.12,6.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000004145 241.0
TLS3_k127_5042822_2 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000008454 153.0
TLS3_k127_5042822_3 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000001569 135.0
TLS3_k127_5042822_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000000000000002875 110.0
TLS3_k127_5042822_5 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000262 78.0
TLS3_k127_5042822_6 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K10943 - - 0.000000000000005751 85.0
TLS3_k127_5057400_0 TatD related DNase K07051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001455 259.0
TLS3_k127_5057400_1 Astacin (Peptidase family M12A) - - - 0.00000000000000000000000000000000000000000000000000000000000000288 242.0
TLS3_k127_5057400_2 - - - - 0.0000002455 57.0
TLS3_k127_5057400_3 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000002819 55.0
TLS3_k127_5087149_0 PALM domain HD hydrolase domain and K09749 - - 0.00000000000000000000000000000000000001439 162.0
TLS3_k127_5101487_0 SMART alpha amylase, catalytic sub domain K01187,K05343 - 3.2.1.1,3.2.1.20,5.4.99.16 0.0 1225.0
TLS3_k127_5101487_1 Protein of unknown function (DUF4256) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 299.0
TLS3_k127_5101487_10 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000001005 151.0
TLS3_k127_5101487_11 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000000000000002716 139.0
TLS3_k127_5101487_12 membrane organization K07126,K07277 - - 0.0000000000000000000000000000000005242 153.0
TLS3_k127_5101487_13 cellulose binding - - - 0.00000000000000000000000000002038 136.0
TLS3_k127_5101487_14 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000000000007872 115.0
TLS3_k127_5101487_15 peptidase C11 clostripain - - - 0.00000000001526 78.0
TLS3_k127_5101487_16 to orf2, orf11, orf12, orf13, orf14, orf15 of fosmid clone 4B7mr3 - - - 0.0003376 52.0
TLS3_k127_5101487_2 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009356 309.0
TLS3_k127_5101487_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003024 262.0
TLS3_k127_5101487_5 DoxX-like family - - - 0.0000000000000000000000000000000000000000000000000002646 189.0
TLS3_k127_5101487_6 Protein of unknown function (DUF805) - - - 0.000000000000000000000000000000000000000000000000002323 184.0
TLS3_k127_5101487_7 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000000000002796 185.0
TLS3_k127_5101487_8 lyase activity - - - 0.00000000000000000000000000000000000000000000000002385 199.0
TLS3_k127_5101487_9 Transcriptional Regulator ArsR Family - - - 0.0000000000000000000000000000000000000000001144 161.0
TLS3_k127_5109265_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 522.0
TLS3_k127_5109265_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008963 506.0
TLS3_k127_5109265_10 hopanoid biosynthesis associated protein HpnK - - - 0.000000000000000002991 96.0
TLS3_k127_5109265_11 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.00000000000000009888 89.0
TLS3_k127_5109265_12 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000001441 84.0
TLS3_k127_5109265_14 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0009112 52.0
TLS3_k127_5109265_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 469.0
TLS3_k127_5109265_3 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000002193 260.0
TLS3_k127_5109265_4 Fic/DOC family - - - 0.0000000000000000000000000000000000000000000000000000000001772 217.0
TLS3_k127_5109265_5 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000521 216.0
TLS3_k127_5109265_6 COG1335 Amidases related to nicotinamidase - - - 0.00000000000000000000000000000000000000002648 161.0
TLS3_k127_5109265_7 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000001881 146.0
TLS3_k127_5109265_8 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000003196 118.0
TLS3_k127_5109265_9 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000001219 105.0
TLS3_k127_5145871_0 TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000000000000000000000000000001509 191.0
TLS3_k127_5145871_1 Histidine kinase - - - 0.000000000000000000000000005559 122.0
TLS3_k127_5158040_0 microcin transport K13895 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 388.0
TLS3_k127_5158040_1 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 303.0
TLS3_k127_5158040_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 294.0
TLS3_k127_5158040_3 ABC transporter (Permease) K02033,K13894 - - 0.0000000000000000000000006495 104.0
TLS3_k127_5196466_0 Outer membrane receptor for Fe3 -dicitrate K16091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 589.0
TLS3_k127_5196466_1 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 575.0
TLS3_k127_5196466_10 anaphase-promoting complex binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 312.0
TLS3_k127_5196466_11 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 302.0
TLS3_k127_5196466_12 Belongs to the bacterial solute-binding protein 9 family K02077,K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 293.0
TLS3_k127_5196466_13 Domain of unknown function (DUF3526) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000245 275.0
TLS3_k127_5196466_14 Polysaccharide biosynthesis C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001114 265.0
TLS3_k127_5196466_15 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000001205 243.0
TLS3_k127_5196466_16 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000001232 243.0
TLS3_k127_5196466_17 Glutamine cyclotransferase K00683 - 2.3.2.5 0.00000000000000000000000000000000000000000000000000000000000001793 224.0
TLS3_k127_5196466_18 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000004691 224.0
TLS3_k127_5196466_19 phenylacetate-CoA ligase activity - - - 0.00000000000000000000000000000000000000000000000764 176.0
TLS3_k127_5196466_2 PFAM cobalamin synthesis protein P47K - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 551.0
TLS3_k127_5196466_20 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000004736 173.0
TLS3_k127_5196466_21 Domain of unknown function (DUF3526) K01992 - - 0.0000000000000000000000000000000000006805 162.0
TLS3_k127_5196466_22 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.000000000000000000000000000000004298 142.0
TLS3_k127_5196466_23 Ribosomal protein L31 K02909 - - 0.00000000000000000000000000001255 121.0
TLS3_k127_5196466_24 Belongs to the Fur family K03711 - - 0.00000000000000006903 85.0
TLS3_k127_5196466_25 with the TIM-barrel fold K07051 - - 0.000000005119 57.0
TLS3_k127_5196466_26 No apical meristem (NAM) protein - - - 0.00014 47.0
TLS3_k127_5196466_27 cobalamin biosynthesis protein - - - 0.0004867 48.0
TLS3_k127_5196466_3 TonB-dependent Receptor Plug Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 507.0
TLS3_k127_5196466_4 ABC transporter permease K02075,K11606 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 358.0
TLS3_k127_5196466_5 Domain of unknown function (DUF3526) K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 354.0
TLS3_k127_5196466_6 Domain of unknown function (DUF3526) K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 340.0
TLS3_k127_5196466_7 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007196 313.0
TLS3_k127_5196466_8 Domain of unknown function (DUF3526) K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 315.0
TLS3_k127_5196466_9 ATPases associated with a variety of cellular activities K02074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 305.0
TLS3_k127_5205091_0 Pyridine nucleotide-disulphide oxidoreductase K03387 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 559.0
TLS3_k127_5205091_1 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 341.0
TLS3_k127_5205091_2 hydrolase, family 3 K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 308.0
TLS3_k127_5205091_3 LysR substrate binding domain K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004739 278.0
TLS3_k127_5205186_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 569.0
TLS3_k127_5205186_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 340.0
TLS3_k127_5205186_2 Fis Family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003663 280.0
TLS3_k127_5205186_3 PFAM Phosphoadenosine phosphosulfate reductase K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000005547 234.0
TLS3_k127_5205186_4 Catalyzes the synthesis of activated sulfate K00860,K00955 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000003835 237.0
TLS3_k127_5205186_5 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000000005953 180.0
TLS3_k127_5205186_6 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000003577 147.0
TLS3_k127_5205186_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000005391 100.0
TLS3_k127_5205186_8 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.0000000000001472 72.0
TLS3_k127_5260896_0 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 539.0
TLS3_k127_5260896_1 Protein of unknown function (DUF692) K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 368.0
TLS3_k127_5260896_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 295.0
TLS3_k127_5260896_3 TIGRFAM mannose-6-phosphate isomerase, class I K01809 - 5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000009279 229.0
TLS3_k127_5260896_4 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) - - - 0.00001567 53.0
TLS3_k127_5284489_0 glucosamine-6-phosphate deaminase K02564 - 3.5.99.6 5.238e-259 822.0
TLS3_k127_5284489_1 intracellular protease K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000002773 208.0
TLS3_k127_5284489_2 Belongs to the peptidase C1 family - - - 0.0000000000000000000000000000000001031 150.0
TLS3_k127_5284489_3 - - - - 0.00000000000000000000611 106.0
TLS3_k127_5284489_4 - - - - 0.0000000000000000000352 98.0
TLS3_k127_5292107_0 diaminopimelate decarboxylase activity K13747 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042401,GO:0042710,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044010,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044764,GO:0045312,GO:0046204,GO:0046983,GO:0048037,GO:0050662,GO:0051704,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 540.0
TLS3_k127_5292107_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 436.0
TLS3_k127_5292107_2 Domain of unknown function (DUF2341) - - - 0.0000000000000000000004978 111.0
TLS3_k127_5292107_3 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.000000000000000000001319 98.0
TLS3_k127_5292618_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 6.701e-221 707.0
TLS3_k127_5292618_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 566.0
TLS3_k127_5292618_2 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003326 291.0
TLS3_k127_5292618_3 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000006769 172.0
TLS3_k127_5292618_4 signal transduction histidine kinase - - - 0.0000000007154 66.0
TLS3_k127_5304849_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 2.815e-197 627.0
TLS3_k127_5304849_1 PFAM Response regulator receiver domain K07668 - - 0.00000000000000000000000000000000000000000000000000000000000005074 233.0
TLS3_k127_5304849_2 Domain of unknown function (DUF4912) K09942 - - 0.00000003579 65.0
TLS3_k127_5329959_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 2888.0
TLS3_k127_5329959_1 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.0 1397.0
TLS3_k127_5329959_10 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000002769 206.0
TLS3_k127_5329959_11 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000005898 180.0
TLS3_k127_5329959_12 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000008286 189.0
TLS3_k127_5329959_13 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000006681 175.0
TLS3_k127_5329959_14 Cyclase dehydrase - - - 0.0000000000000000000000000000000000000000003339 168.0
TLS3_k127_5329959_15 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.0000000000000000000000000000000000000008675 166.0
TLS3_k127_5329959_16 PFAM KWG Leptospira - - - 0.0000000000000000000000000000000007649 145.0
TLS3_k127_5329959_17 Histidine kinase - - - 0.00000000000000000000000000000000501 148.0
TLS3_k127_5329959_18 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000009323 139.0
TLS3_k127_5329959_19 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway - - - 0.00000000000000000000000000000001133 138.0
TLS3_k127_5329959_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 591.0
TLS3_k127_5329959_20 - - - - 0.000000000000000000000000001192 123.0
TLS3_k127_5329959_21 - - - - 0.000000000000000000000000002646 128.0
TLS3_k127_5329959_22 HxlR-like helix-turn-helix - - - 0.00000000000000000000001239 106.0
TLS3_k127_5329959_23 - - - - 0.00000000000000000000002246 115.0
TLS3_k127_5329959_24 Gaf domain - - - 0.00000000000000000000005829 113.0
TLS3_k127_5329959_25 Integral membrane sensor signal transduction histidine kinase K10125 - 2.7.13.3 0.000000000000000003894 96.0
TLS3_k127_5329959_26 - - - - 0.000000000000000006671 90.0
TLS3_k127_5329959_27 Psort location Cytoplasmic, score - - - 0.00000000000004167 81.0
TLS3_k127_5329959_28 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000005414 77.0
TLS3_k127_5329959_29 Pfam Response regulator receiver - - - 0.0000000002076 70.0
TLS3_k127_5329959_3 pfam abc-1 K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 504.0
TLS3_k127_5329959_30 response regulator, receiver K02030,K13040 - 2.7.13.3 0.000000001219 71.0
TLS3_k127_5329959_31 MORN repeat variant - - - 0.000000003314 64.0
TLS3_k127_5329959_32 granule-associated protein - - - 0.000000003809 62.0
TLS3_k127_5329959_33 Response regulator receiver domain - - - 0.00000001571 64.0
TLS3_k127_5329959_34 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.00000001945 66.0
TLS3_k127_5329959_35 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.00000002224 65.0
TLS3_k127_5329959_36 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0002582 46.0
TLS3_k127_5329959_4 ATPase component of ABC transporters with duplicated ATPase domain K15738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 422.0
TLS3_k127_5329959_5 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 378.0
TLS3_k127_5329959_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 288.0
TLS3_k127_5329959_7 Zn-dependent protease with chaperone function - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001464 279.0
TLS3_k127_5329959_8 COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1 K03772,K03773 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000004289 232.0
TLS3_k127_5329959_9 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000007606 219.0
TLS3_k127_5332953_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006401 276.0
TLS3_k127_5332953_1 - - - - 0.0000000000000000000000000000000000000000000000000000006773 210.0
TLS3_k127_5332953_2 helix_turn_helix, Lux Regulon - - - 0.00000000000001982 79.0
TLS3_k127_5334408_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 407.0
TLS3_k127_5334408_1 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003424 266.0
TLS3_k127_5334408_2 nuclear chromosome segregation - - - 0.000002081 61.0
TLS3_k127_5334925_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 2.223e-200 632.0
TLS3_k127_5334925_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 385.0
TLS3_k127_5334925_10 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000008013 126.0
TLS3_k127_5334925_11 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000004597 105.0
TLS3_k127_5334925_13 metallopeptidase activity - - - 0.000000007557 68.0
TLS3_k127_5334925_14 - - - - 0.000002317 53.0
TLS3_k127_5334925_15 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00008963 47.0
TLS3_k127_5334925_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 330.0
TLS3_k127_5334925_3 protein conserved in bacteria K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 343.0
TLS3_k127_5334925_4 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 327.0
TLS3_k127_5334925_5 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 327.0
TLS3_k127_5334925_6 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000116 291.0
TLS3_k127_5334925_7 Peptidase M15 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001831 282.0
TLS3_k127_5334925_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003666 254.0
TLS3_k127_5334925_9 - - - - 0.00000000000000000000000000000000001008 157.0
TLS3_k127_5337190_0 Protein of unknown function (DUF1349) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 338.0
TLS3_k127_5337190_1 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000009376 172.0
TLS3_k127_5337190_2 Transglutaminase-like superfamily - - - 0.0000001051 57.0
TLS3_k127_5357848_0 lipopolysaccharide-transporting ATPase activity K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008403 321.0
TLS3_k127_5357848_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 317.0
TLS3_k127_5357848_2 orotidine-5'-phosphate decarboxylase activity K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000002242 264.0
TLS3_k127_5357848_3 phosphoprotein phosphatase activity K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000001128 188.0
TLS3_k127_5357848_4 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000002206 199.0
TLS3_k127_5357848_5 MATE efflux family protein - - - 0.00000000000000000000000000000000000000000005744 177.0
TLS3_k127_5357848_6 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000001106 156.0
TLS3_k127_5357848_7 lipopolysaccharide transmembrane transporter activity K09774,K11719 - - 0.00000000000000000000000000000000000005722 154.0
TLS3_k127_5357848_8 lipopolysaccharide transport K04744 - - 0.00000000000000000000000000002801 135.0
TLS3_k127_5357848_9 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.0000000000000000000000000002764 123.0
TLS3_k127_5393115_0 type III restriction protein res subunit K01153 - 3.1.21.3 8.766e-320 992.0
TLS3_k127_5393115_1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 4.644e-258 814.0
TLS3_k127_5393115_2 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 427.0
TLS3_k127_5393115_3 PFAM Alcohol dehydrogenase, zinc-binding K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 377.0
TLS3_k127_5393115_4 Pectate lyase K01728 - 4.2.2.2 0.0000000000000000000000000000000000000000000000000000003737 208.0
TLS3_k127_5393115_5 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03087 - - 0.0000000000000000000000000000000000000000000000000001861 189.0
TLS3_k127_5393115_6 OmpA family - - - 0.000000000000001715 91.0
TLS3_k127_5406748_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355,K18220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 370.0
TLS3_k127_5406748_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000007298 252.0
TLS3_k127_5406748_2 With S4 and S5 plays an important role in translational accuracy K02950 - - 0.00000000000000000000000000000000000000000000000000000000000007492 216.0
TLS3_k127_5406748_3 rRNA binding K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000001297 186.0
TLS3_k127_5406748_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000001511 125.0
TLS3_k127_5406748_5 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000001301 68.0
TLS3_k127_5418750_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K01885,K02341,K02343 - 2.7.7.7,6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 421.0
TLS3_k127_5418750_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 419.0
TLS3_k127_5418750_2 unfolded protein binding K04083 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008 - 0.000000000000000000000000000000000000000000000000000000000000000009312 236.0
TLS3_k127_5418750_3 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000001625 160.0
TLS3_k127_5418750_4 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000001837 150.0
TLS3_k127_5418750_5 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000002726 150.0
TLS3_k127_5418750_6 - K07341 - - 0.00000000000000000000000000000000002149 138.0
TLS3_k127_5418750_7 PFAM SpoVT AbrB K07172,K18842 - - 0.00000000000000000000008356 98.0
TLS3_k127_5418750_8 sigma factor antagonist activity - - - 0.000000000000000000009531 104.0
TLS3_k127_5420566_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K00556,K03218,K03437 - 2.1.1.185,2.1.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000005397 255.0
TLS3_k127_5420566_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000001417 166.0
TLS3_k127_5420566_2 PA14 domain - - - 0.00000000000000000000000001527 127.0
TLS3_k127_5420566_4 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000000000000000003106 110.0
TLS3_k127_5420566_5 tail collar domain protein - - - 0.000000000000001857 91.0
TLS3_k127_5420566_6 PilT protein domain protein - - - 0.000000000000002187 81.0
TLS3_k127_5420566_7 COGs COG5421 Transposase - - - 0.0000000000003312 75.0
TLS3_k127_5420566_8 - - - - 0.0001427 48.0
TLS3_k127_5434273_0 Psort location Cytoplasmic, score 8.87 K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000001319 193.0
TLS3_k127_5434273_1 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000003434 145.0
TLS3_k127_5434273_2 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000008344 67.0
TLS3_k127_5434273_3 Peptidase family C25 - - - 0.000003691 60.0
TLS3_k127_5434688_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702 - 2.4.1.20 1.793e-218 745.0
TLS3_k127_5434688_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 584.0
TLS3_k127_5434688_10 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit - - - 0.00000000000000000000000000000003819 139.0
TLS3_k127_5434688_12 PFAM Calcium calmodulin dependent protein kinase II Association - - - 0.0000000000000007833 91.0
TLS3_k127_5434688_13 radical SAM domain protein - - - 0.0000000000008664 69.0
TLS3_k127_5434688_14 cellulose 1,4-beta-cellobiosidase activity K01278,K01727,K03561,K12287,K21449 - 3.4.14.5,4.2.2.1 0.00000000007775 68.0
TLS3_k127_5434688_15 COG3250 Beta-galactosidase beta-glucuronidase K01190 - 3.2.1.23 0.00007639 55.0
TLS3_k127_5434688_2 import. Responsible for energy coupling to the transport system K10545 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 449.0
TLS3_k127_5434688_3 PFAM Periplasmic binding protein domain K10543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 314.0
TLS3_k127_5434688_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 311.0
TLS3_k127_5434688_5 MFS_1 like family K03291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 304.0
TLS3_k127_5434688_6 Belongs to the binding-protein-dependent transport system permease family K10544 - - 0.000000000000000000000000000000000000000000000000000000000000000006382 248.0
TLS3_k127_5434688_7 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000002734 213.0
TLS3_k127_5434688_8 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000001056 184.0
TLS3_k127_5434688_9 ergosterol biosynthetic process K02291,K18163 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.5.1.32,2.5.1.99 0.000000000000000000000000000000001259 140.0
TLS3_k127_5435581_0 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 364.0
TLS3_k127_5435581_1 photoreceptor activity K03413,K07684,K07689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 394.0
TLS3_k127_5435581_10 - - - - 0.00000000000000001152 89.0
TLS3_k127_5435581_11 Glycosyl hydrolase family 48 - - - 0.000000003458 72.0
TLS3_k127_5435581_12 COG3325 Chitinase - - - 0.0002026 56.0
TLS3_k127_5435581_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 365.0
TLS3_k127_5435581_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 GO:0003674,GO:0003824,GO:0004791,GO:0006810,GO:0006897,GO:0006909,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0016192,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0030587,GO:0031154,GO:0032502,GO:0042221,GO:0042592,GO:0045454,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051703,GO:0051704,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0090702,GO:0097237,GO:0098657,GO:0098754,GO:0098869,GO:0099120,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 336.0
TLS3_k127_5435581_4 TIGRFAM Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000001591 214.0
TLS3_k127_5435581_5 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000293 205.0
TLS3_k127_5435581_6 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000002285 191.0
TLS3_k127_5435581_7 repeat protein - - - 0.0000000000000000000000000000000000000000166 179.0
TLS3_k127_5435581_8 ABC transporter K01990 - - 0.000000000000000000000000000000000000009365 153.0
TLS3_k127_5435581_9 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.0000000000000000000009639 113.0
TLS3_k127_5455871_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 499.0
TLS3_k127_5455871_1 phosphorelay signal transduction system K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004152 481.0
TLS3_k127_5455871_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000126 164.0
TLS3_k127_5455871_11 Chemotaxis phosphatase CheX K03409 - - 0.00000000000000000000000000000000005361 140.0
TLS3_k127_5455871_12 Domain of unknown function (DUF2341) - - - 0.0000000000000000000000000000000005295 150.0
TLS3_k127_5455871_13 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000001854 130.0
TLS3_k127_5455871_14 PFAM chemotaxis sensory transducer K03406 - - 0.0000000000000000000000000002931 122.0
TLS3_k127_5455871_16 Chemotaxis phosphatase CheX - - - 0.0000148 54.0
TLS3_k127_5455871_17 cheY-homologous receiver domain K03413 - - 0.0005538 45.0
TLS3_k127_5455871_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 429.0
TLS3_k127_5455871_3 Glucose sorbosone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 334.0
TLS3_k127_5455871_4 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001643 289.0
TLS3_k127_5455871_5 Protein of unknown function (DUF3365) K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003671 265.0
TLS3_k127_5455871_6 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001075 271.0
TLS3_k127_5455871_7 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000000000000000000000001446 181.0
TLS3_k127_5455871_8 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000000000000000000005126 186.0
TLS3_k127_5455871_9 addiction module antidote protein HigA K07110,K21686 - - 0.00000000000000000000000000000000000000000000001022 183.0
TLS3_k127_5497524_0 ABC transporter substrate-binding protein PnrA-like K02058,K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 379.0
TLS3_k127_5497524_1 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 352.0
TLS3_k127_5497524_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 341.0
TLS3_k127_5497524_3 PFAM ABC transporter related K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 348.0
TLS3_k127_5497524_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009229 333.0
TLS3_k127_5497524_5 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002887 287.0
TLS3_k127_5497524_6 Thymidylate kinase K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000005832 238.0
TLS3_k127_5497524_7 Nucleoside-binding outer membrane protein - - - 0.0000000000000000000000001001 111.0
TLS3_k127_5497524_8 ChrR Cupin-like domain - - - 0.00000000000000000000128 99.0
TLS3_k127_5532635_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 419.0
TLS3_k127_5532635_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000001398 163.0
TLS3_k127_5532635_2 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.0000000000000000000000000000000007155 137.0
TLS3_k127_5532635_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000005778 65.0
TLS3_k127_5532635_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000134 44.0
TLS3_k127_5535011_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.433e-271 851.0
TLS3_k127_5535011_1 DNA primase activity K02316,K17680 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001926 263.0
TLS3_k127_5535011_2 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006524 260.0
TLS3_k127_5535011_3 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000007639 242.0
TLS3_k127_5535011_4 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000004253 177.0
TLS3_k127_5535011_5 peptidyl-tyrosine sulfation - - - 0.0006602 52.0
TLS3_k127_5550368_0 GTPase activity K03150,K03650 - 4.1.99.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 317.0
TLS3_k127_5550368_1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000002211 137.0
TLS3_k127_5550368_2 Conserved repeat domain K01317 - 3.4.21.10 0.000000000000000000000000000054 126.0
TLS3_k127_5553267_0 glucose-1-phosphate adenylyltransferase activity K00973,K02096,K02286,K02290,K05378,K05379,K05380 GO:0005575,GO:0005622,GO:0005623,GO:0009579,GO:0016020,GO:0034357,GO:0042651,GO:0044424,GO:0044436,GO:0044464 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 336.0
TLS3_k127_5553267_1 Hydrolase - - - 0.0000000000000417 83.0
TLS3_k127_5563121_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 1.226e-287 910.0
TLS3_k127_5563121_1 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 321.0
TLS3_k127_5563121_2 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000005705 103.0
TLS3_k127_5563121_3 - - - - 0.00000000000000008238 90.0
TLS3_k127_5568247_0 membrane insertase activity K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 359.0
TLS3_k127_5568247_1 GTPase activity K03150,K03650 - 4.1.99.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 325.0
TLS3_k127_5568247_2 Transcriptional regulator - - - 0.0000007346 55.0
TLS3_k127_5577674_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.33e-260 814.0
TLS3_k127_5577674_1 TIGRFAM Por secretion system C-terminal sorting domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 614.0
TLS3_k127_5577674_10 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000005429 221.0
TLS3_k127_5577674_11 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000001061 209.0
TLS3_k127_5577674_12 Protein of unknown function DUF47 K02039,K07220 - - 0.0000000000000000000000000000000000000000000000000005705 191.0
TLS3_k127_5577674_13 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000001261 199.0
TLS3_k127_5577674_14 PALM domain HD hydrolase domain and K09749 - - 0.0000000000000000000000000000000000863 151.0
TLS3_k127_5577674_15 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000157 135.0
TLS3_k127_5577674_16 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000832 122.0
TLS3_k127_5577674_17 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657,K07658 - - 0.000000000000000000000000002641 116.0
TLS3_k127_5577674_18 transcription factor binding - - - 0.0000000000000000000000001147 114.0
TLS3_k127_5577674_19 protein conserved in bacteria K09928 - - 0.000000000000002221 85.0
TLS3_k127_5577674_2 PFAM CBS domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 463.0
TLS3_k127_5577674_20 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000003349 79.0
TLS3_k127_5577674_21 Prokaryotic homologs of the JAB domain - - - 0.00000005602 57.0
TLS3_k127_5577674_22 protein related to plant photosystem II stability assembly factor - - - 0.0000004996 60.0
TLS3_k127_5577674_23 TonB-dependent receptor K02014 - - 0.000002636 53.0
TLS3_k127_5577674_24 CBD_II - - - 0.00006563 53.0
TLS3_k127_5577674_3 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 423.0
TLS3_k127_5577674_4 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 398.0
TLS3_k127_5577674_5 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 383.0
TLS3_k127_5577674_6 domain protein K01051,K10297,K18650 - 3.1.1.11,3.2.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 375.0
TLS3_k127_5577674_7 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 308.0
TLS3_k127_5577674_8 Pectate lyase K01728 - 4.2.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001029 283.0
TLS3_k127_5577674_9 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000006543 244.0
TLS3_k127_55837_0 DEAD DEAH box K03724 - - 0.0 1337.0
TLS3_k127_55837_1 ABC transporter, ATP-binding protein - - - 1.063e-242 766.0
TLS3_k127_55837_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000001024 162.0
TLS3_k127_55837_12 Glucose / Sorbosone dehydrogenase K20276 - - 0.0000000000000000000000000000000000000004807 166.0
TLS3_k127_55837_13 HipA N-terminal domain K07154 - 2.7.11.1 0.00000000000000000000000000000000000008257 144.0
TLS3_k127_55837_14 glucose sorbosone - - - 0.0000000000000000000000000000000000004502 156.0
TLS3_k127_55837_15 Pirin K06911 - - 0.000000000000000000000000000000000001162 147.0
TLS3_k127_55837_16 beta (1-6) glucans synthase - - - 0.000000000000000000000000000000002307 144.0
TLS3_k127_55837_17 Helix-turn-helix K21498 - - 0.00000000000000000000000000151 114.0
TLS3_k127_55837_18 transcriptional regulator - - - 0.00000000000000000000002374 101.0
TLS3_k127_55837_19 OmpA MotB domain protein K02557 - - 0.000000000000000000003364 109.0
TLS3_k127_55837_2 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 599.0
TLS3_k127_55837_21 Late embryogenesis abundant protein - - - 0.000000008309 64.0
TLS3_k127_55837_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 514.0
TLS3_k127_55837_4 Type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 504.0
TLS3_k127_55837_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 415.0
TLS3_k127_55837_6 peptidase activity, acting on L-amino acid peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 403.0
TLS3_k127_55837_7 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 361.0
TLS3_k127_55837_8 Pfam:HipA_N K07154 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 323.0
TLS3_k127_55837_9 Uncharacterised conserved protein (DUF2156) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 317.0
TLS3_k127_5618299_0 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 448.0
TLS3_k127_5618299_1 Aminotransferase class-V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 328.0
TLS3_k127_5618299_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000006029 213.0
TLS3_k127_5641293_0 Cation transporter/ATPase, N-terminus - - - 1.02e-269 847.0
TLS3_k127_5641293_1 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005114 304.0
TLS3_k127_5641293_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001938 229.0
TLS3_k127_5641293_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000001696 154.0
TLS3_k127_5641293_4 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000686 103.0
TLS3_k127_5641293_5 ExbD TolR K03559 - - 0.00000000000000000001114 98.0
TLS3_k127_5641293_6 Belongs to the glycosyl hydrolase 43 family - - - 0.000000000000001341 83.0
TLS3_k127_5641293_7 Cobalamin synthesis protein cobW C-terminal domain - - - 0.00000000602 57.0
TLS3_k127_5641293_8 Belongs to the peptidase S8 family - - - 0.00000001896 66.0
TLS3_k127_5641293_9 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000009376 56.0
TLS3_k127_5646897_0 RNA polymerase recycling family C-terminal - - - 2.73e-220 718.0
TLS3_k127_5646897_1 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 456.0
TLS3_k127_5646897_2 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000000000000000000000000000000000000002239 235.0
TLS3_k127_5646897_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.3.13 0.0000000000000000000000000000000000000000000003027 174.0
TLS3_k127_5646897_4 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.00000000000000000000000000001357 128.0
TLS3_k127_5646897_5 DNA-templated transcription, initiation K03088,K16872 - 2.3.1.207 0.00000000000000000038 96.0
TLS3_k127_5646897_6 MORN repeat protein - - - 0.00000002085 64.0
TLS3_k127_5646897_7 Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation - GO:0005575,GO:0016020 - 0.000001435 54.0
TLS3_k127_5657742_0 Associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 434.0
TLS3_k127_5657742_1 protein (some members contain a von Willebrand factor type A (vWA) domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 367.0
TLS3_k127_5657742_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000387 201.0
TLS3_k127_5657742_3 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000004551 79.0
TLS3_k127_5684383_0 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 604.0
TLS3_k127_5684383_1 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 406.0
TLS3_k127_5684383_10 Thioredoxin domain - - - 0.000000000000000000008517 95.0
TLS3_k127_5684383_11 WG containing repeat - - - 0.000000000000008843 80.0
TLS3_k127_5684383_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 300.0
TLS3_k127_5684383_3 inositol monophosphate 1-phosphatase activity K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000007271 225.0
TLS3_k127_5684383_4 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.00000000000000000000000000000000000000000000000000000000004499 214.0
TLS3_k127_5684383_5 PFAM S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000001577 206.0
TLS3_k127_5684383_6 PFAM sigma-54 factor interaction domain-containing protein K02481 - - 0.0000000000000000000000000000000000000000000000000000005539 199.0
TLS3_k127_5684383_7 ATP-independent chaperone mediated protein folding - - - 0.000000000000000000000000000000000000000000000001192 181.0
TLS3_k127_5684383_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000003399 108.0
TLS3_k127_5684383_9 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000001647 105.0
TLS3_k127_5770406_0 TIGRFAM DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000001681 252.0
TLS3_k127_5770406_1 GTP-binding protein TypA K06207 - - 0.0000000000000000000000000000000000000000000000000000001618 199.0
TLS3_k127_5770406_2 Amino-acid N-acetyltransferase K14682 - 2.3.1.1 0.000000000000000000000000000000000000000000000000004271 186.0
TLS3_k127_5770406_3 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family K01406,K13276,K20276 - 3.4.24.40 0.0000000000000000000000000000000000000000000000004164 203.0
TLS3_k127_5770406_5 regulation of translation K03530 - - 0.000000000000000000000000001261 115.0
TLS3_k127_5770406_7 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000001718 102.0
TLS3_k127_58011_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009719 370.0
TLS3_k127_58011_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K01563 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000003194 263.0
TLS3_k127_58011_2 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000002676 247.0
TLS3_k127_58011_3 transcriptional regulator - - - 0.00000000000000000000000000000001043 139.0
TLS3_k127_58011_4 Outer membrane protein, OMP85 family K07277 - - 0.000000000000001263 90.0
TLS3_k127_5809145_0 PFAM Glycoside hydrolase 15-related - - - 1.378e-279 879.0
TLS3_k127_5809145_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 6.869e-224 708.0
TLS3_k127_5809145_10 - - - - 0.00000003677 55.0
TLS3_k127_5809145_11 extracellular matrix structural constituent K13714 - 3.2.1.96,3.5.1.28 0.00000005274 68.0
TLS3_k127_5809145_12 Transcriptional regulator K07726 - - 0.00001885 53.0
TLS3_k127_5809145_2 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 462.0
TLS3_k127_5809145_3 response regulator, receiver K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 453.0
TLS3_k127_5809145_4 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 427.0
TLS3_k127_5809145_5 Autotransporter beta-domain - - - 0.00000000000000000000000000000002446 150.0
TLS3_k127_5809145_6 Domain of unknown function (DUF2341) - - - 0.0000000000000000000000000001387 135.0
TLS3_k127_5809145_7 - - - - 0.0000000000000000000002274 103.0
TLS3_k127_5809145_8 PAS domain - - - 0.0000000000000000000004226 100.0
TLS3_k127_5809145_9 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000357 103.0
TLS3_k127_5860385_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 313.0
TLS3_k127_5860385_1 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001583 243.0
TLS3_k127_5860385_10 Acetyl xylan esterase (AXE1) - - - 0.0000135 59.0
TLS3_k127_5860385_11 penicillin-binding protein - - - 0.00003084 58.0
TLS3_k127_5860385_2 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000003648 243.0
TLS3_k127_5860385_3 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000003864 178.0
TLS3_k127_5860385_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000005729 146.0
TLS3_k127_5860385_6 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000001518 123.0
TLS3_k127_5860385_7 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000005505 97.0
TLS3_k127_5860385_8 Glycosyltransferase like family 2 - - - 0.00000000004706 74.0
TLS3_k127_5860385_9 Two component regulator propeller - - - 0.0000003805 64.0
TLS3_k127_5861925_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 521.0
TLS3_k127_5861925_1 PFAM Uncharacterised protein family (UPF0093) K08973 - - 0.000000000000000000000000000000000000000000181 166.0
TLS3_k127_5861925_2 C-type lectin (CTL) or carbohydrate-recognition domain (CRD) - - - 0.000000000000000000000000000000000001012 146.0
TLS3_k127_5861925_3 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.00000000000000000002589 102.0
TLS3_k127_5884993_0 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.00000000000000000000000000000000000000000000000000000000000002181 236.0
TLS3_k127_5890413_0 serine-type D-Ala-D-Ala carboxypeptidase activity K05366 - 2.4.1.129,3.4.16.4 1.25e-241 769.0
TLS3_k127_5890413_1 serine-type D-Ala-D-Ala carboxypeptidase activity K05366 - 2.4.1.129,3.4.16.4 9.013e-196 637.0
TLS3_k127_5890413_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 576.0
TLS3_k127_5890413_3 of the beta-lactamase superfamily I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000123 254.0
TLS3_k127_5890413_4 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000001615 135.0
TLS3_k127_5890413_5 Sporulation protein YtfJ - - - 0.0000000000000000883 85.0
TLS3_k127_5890413_6 Outer membrane protein beta-barrel domain - - - 0.0000004235 60.0
TLS3_k127_5890413_7 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K04772 - 3.4.21.107 0.00001734 49.0
TLS3_k127_5892769_0 Vitamin K epoxide reductase family - - - 1.389e-239 766.0
TLS3_k127_5892769_1 D-isomer specific 2-hydroxyacid dehydrogenase K03778 GO:0000166,GO:0003674,GO:0003824,GO:0004457,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006067,GO:0006082,GO:0006083,GO:0006089,GO:0006090,GO:0006091,GO:0006103,GO:0006105,GO:0006113,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008720,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0015942,GO:0015980,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019318,GO:0019362,GO:0019637,GO:0019660,GO:0019664,GO:0019666,GO:0019693,GO:0019752,GO:0032787,GO:0034308,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0050896,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0070404,GO:0071704,GO:0072521,GO:0072524,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901615 1.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 447.0
TLS3_k127_5892769_2 Belongs to the glycosyl hydrolase 26 family K01179 GO:0003674,GO:0003824,GO:0004553,GO:0008810,GO:0016787,GO:0016798 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 392.0
TLS3_k127_5892769_3 DNA-binding transcription factor activity K02529,K03604 - - 0.000000000000000000000000000000000000000000000000000000000000000001532 245.0
TLS3_k127_5892769_4 L-lactate permease K03303 - - 0.000000000000000000000000000000000000000000001528 170.0
TLS3_k127_5892769_5 Fibronectin type III-like domain K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000003001 168.0
TLS3_k127_5895842_0 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 337.0
TLS3_k127_5895842_1 von Willebrand factor (vWF) type A domain K07114,K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 327.0
TLS3_k127_5899927_0 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 520.0
TLS3_k127_5899927_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 475.0
TLS3_k127_5899927_2 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003651 251.0
TLS3_k127_5899927_3 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000002048 173.0
TLS3_k127_5899927_4 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000003255 147.0
TLS3_k127_5899927_5 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.000000000000000000000000009617 115.0
TLS3_k127_5899927_6 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.0000000000000233 79.0
TLS3_k127_5921645_0 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000006343 201.0
TLS3_k127_5931147_0 protein refolding K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 2.05e-233 734.0
TLS3_k127_5931147_1 unfolded protein binding K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000009754 242.0
TLS3_k127_5931147_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K02652,K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000002936 176.0
TLS3_k127_5931147_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000001775 171.0
TLS3_k127_5931147_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000134 140.0
TLS3_k127_5953934_0 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009464 274.0
TLS3_k127_5953934_1 PhnA Zinc-Ribbon K06193 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000006578 182.0
TLS3_k127_5953934_2 FR47-like protein - - - 0.00000000000000000000000000000000000000003675 161.0
TLS3_k127_5953934_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976,K19693,K21572 - - 0.00000000000000000000001237 104.0
TLS3_k127_5953934_4 DinB family - - - 0.000000001372 65.0
TLS3_k127_596555_0 chitin binding K01179,K01218 - 3.2.1.4,3.2.1.78 0.000000000000000000000000000000000000000000000000000000000008897 222.0
TLS3_k127_596555_1 Dual specificity phosphatase, catalytic domain - - - 0.0000000000000000000000000000000000001721 146.0
TLS3_k127_596555_2 - - - - 0.000000000000009071 79.0
TLS3_k127_5970592_0 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000001683 143.0
TLS3_k127_5970592_1 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000007803 118.0
TLS3_k127_5970592_2 RelE toxin of RelE / RelB toxin-antitoxin system - - - 0.0000000000000000003222 91.0
TLS3_k127_5970592_4 PFAM Helix-turn-helix K07726 - - 0.0002641 49.0
TLS3_k127_6012759_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01153 - 3.1.21.3 0.0 1142.0
TLS3_k127_6012759_1 PFAM restriction modification system DNA specificity domain K01154 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007352 598.0
TLS3_k127_6012759_2 Virulence protein RhuM family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 451.0
TLS3_k127_6012759_3 Protein of unknown function (DUF1016) - - - 0.0000000000003085 70.0
TLS3_k127_6022284_0 FGGY family of carbohydrate kinases, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 608.0
TLS3_k127_6022284_1 PFAM tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 584.0
TLS3_k127_6022284_2 Belongs to the xylose isomerase family K01805 - 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000001199 251.0
TLS3_k127_6022284_3 iron-sulfur transferase activity K04488,K07126,K13819 - - 0.0000000000000000000000000000000000000003257 161.0
TLS3_k127_6022284_4 FeS assembly protein SufB K09014 - - 0.00000000000000000000001947 106.0
TLS3_k127_6032016_0 Belongs to the GPI family K01810 GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 596.0
TLS3_k127_6032016_1 alpha-L-arabinofuranosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008946 283.0
TLS3_k127_6032016_2 alpha-L-arabinofuranosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001038 258.0
TLS3_k127_6032016_3 - - - - 0.0000000000009751 69.0
TLS3_k127_6032501_0 mismatched DNA binding K03555 GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008301,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0030983,GO:0031323,GO:0032136,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - 8.565e-196 633.0
TLS3_k127_6032501_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000001029 73.0
TLS3_k127_6038678_0 dockerin type K18197 - 4.2.2.23 3.175e-227 723.0
TLS3_k127_6038678_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 4.558e-205 661.0
TLS3_k127_6038678_10 Lipase (class 3) - - - 0.0000000000000000000000000000001376 136.0
TLS3_k127_6038678_12 protein conserved in bacteria K09928 - - 0.000000000005078 74.0
TLS3_k127_6038678_13 Transporter associated domain K03699 - - 0.00000000007885 66.0
TLS3_k127_6038678_14 protein secretion K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000001607 74.0
TLS3_k127_6038678_15 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.0000003704 53.0
TLS3_k127_6038678_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 561.0
TLS3_k127_6038678_3 Carbohydrate esterase, sialic acid-specific acetylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 373.0
TLS3_k127_6038678_4 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 313.0
TLS3_k127_6038678_5 Peptidase, S8 S53 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006187 293.0
TLS3_k127_6038678_6 Domain of unknown function (DUF2341) - - - 0.0000000000000000000000000000000000000000000000000000000000004985 234.0
TLS3_k127_6038678_7 addiction module antidote protein HigA K07110,K21686 - - 0.00000000000000000000000000000000000000000000000000004899 198.0
TLS3_k127_6038678_8 Laminin G domain - - - 0.000000000000000000000000000000000001233 158.0
TLS3_k127_6038678_9 Belongs to the glycosyl hydrolase 43 family - - - 0.0000000000000000000000000000000000143 152.0
TLS3_k127_6041587_0 phenylalanine-tRNA ligase activity K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000002547 230.0
TLS3_k127_6041587_1 Esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000003747 204.0
TLS3_k127_6041587_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000002062 132.0
TLS3_k127_6041587_3 translation initiation factor activity K02520 GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - 0.000000000000000000000003244 107.0
TLS3_k127_6041587_4 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000001153 70.0
TLS3_k127_6044222_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 465.0
TLS3_k127_6044222_1 metallopeptidase activity K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 335.0
TLS3_k127_6044222_2 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007133 271.0
TLS3_k127_6044222_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000005646 228.0
TLS3_k127_6044222_4 PFAM Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000013 188.0
TLS3_k127_6044222_5 ABC transporter K01990 - - 0.00000000000000000000000000000000001266 149.0
TLS3_k127_6044222_6 transmembrane transport K01992 - - 0.0000000000000001689 88.0
TLS3_k127_6064806_0 nucleotide-excision repair K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000252 274.0
TLS3_k127_6064806_1 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000001796 141.0
TLS3_k127_6064806_2 O-Antigen ligase - - - 0.0000000000000000000000000000000001741 152.0
TLS3_k127_6064806_3 Belongs to the glycosyl hydrolase 26 family - - - 0.00000000000000000000000000106 126.0
TLS3_k127_6064806_4 serine-type endopeptidase activity - - - 0.00002467 58.0
TLS3_k127_6085300_0 (ABC) transporter K06020 GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 2.868e-245 768.0
TLS3_k127_6085300_1 Transcriptional regulator, AbiEi antitoxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 431.0
TLS3_k127_6085300_2 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0000000000000000000003241 101.0
TLS3_k127_6085300_3 - - - - 0.00000000006855 69.0
TLS3_k127_6085300_4 DnaJ molecular chaperone homology domain - - - 0.000009238 59.0
TLS3_k127_6092195_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 600.0
TLS3_k127_6092195_1 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 334.0
TLS3_k127_6092195_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 312.0
TLS3_k127_6092195_3 signal sequence binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005886 256.0
TLS3_k127_6135086_0 DNA photolyase activity K03716 - 4.1.99.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 327.0
TLS3_k127_6135086_1 Protein of unknown function (DUF2797) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004282 282.0
TLS3_k127_6135086_2 ArsC family K00537 - 1.20.4.1 0.000000000000000000000000000000000000156 150.0
TLS3_k127_6135086_3 Protein of unknown function (DUF4230) - - - 0.000000000000000004255 90.0
TLS3_k127_6139566_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 504.0
TLS3_k127_6139566_1 TIGRFAM DNA-3-methyladenine glycosylase I K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 343.0
TLS3_k127_6139566_2 depolymerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 345.0
TLS3_k127_6145591_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 542.0
TLS3_k127_6145591_1 Xylose isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001545 290.0
TLS3_k127_6145591_2 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005706 257.0
TLS3_k127_6145591_3 3-dehydroquinate synthase K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000003493 214.0
TLS3_k127_6145591_4 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000000000000000000001025 171.0
TLS3_k127_6145591_5 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.0000000000000000000000000000000716 136.0
TLS3_k127_6145591_6 Xylose isomerase-like TIM barrel - - - 0.000000000000000000117 100.0
TLS3_k127_6145702_0 addiction module antidote protein HigA K07110,K21686 - - 0.0000000000000000000000000000000000000000000000000003035 201.0
TLS3_k127_6146429_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 337.0
TLS3_k127_6146429_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604,K03500 GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.1.176,2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009587 277.0
TLS3_k127_6146429_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000001048 133.0
TLS3_k127_6146429_3 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000000000001901 86.0
TLS3_k127_6147485_0 PFAM GlcNAc-PI de-N-acetylase - - - 3.512e-228 734.0
TLS3_k127_6147485_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 595.0
TLS3_k127_6147485_2 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009063 570.0
TLS3_k127_6147485_3 Ricin-type beta-trefoil K06113 - 3.2.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006817 286.0
TLS3_k127_6147485_4 Protein of unknown function (DUF2911) - - - 0.000000000000000000000000000000000000000000000000002403 201.0
TLS3_k127_6147485_5 addiction module antidote protein HigA K07110,K21686 - - 0.00000000000000000000000000001738 129.0
TLS3_k127_6155227_0 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 327.0
TLS3_k127_6155227_1 peptidyl-serine autophosphorylation - - - 0.0000000000000000000000000000000000000000000000000006249 196.0
TLS3_k127_6155227_2 Protein conserved in bacteria K01083 - 3.1.3.8 0.00000000000000000000000000000000000000000000002058 198.0
TLS3_k127_6155227_3 HIRAN domain - - - 0.000000000000000000000000000000000000000000001498 173.0
TLS3_k127_615769_0 type VI secretion protein K11900 - - 4.971e-213 672.0
TLS3_k127_615769_1 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.00000000000000000000000000000000000000000000002662 176.0
TLS3_k127_615769_2 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ K11910 - - 0.0000000000000000000000000000000000000001331 164.0
TLS3_k127_6159424_0 PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000001701 232.0
TLS3_k127_6159424_1 L-threonine 3-dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000517 229.0
TLS3_k127_6159424_2 6-phosphogluconolactonase activity - - - 0.0000000000000000000000000000009211 142.0
TLS3_k127_6177002_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.19e-197 631.0
TLS3_k127_6177002_1 histidinol dehydrogenase activity K00013,K15509 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 535.0
TLS3_k127_6177002_10 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001731 265.0
TLS3_k127_6177002_11 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004799 226.0
TLS3_k127_6177002_12 peptidase activity K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000002404 197.0
TLS3_k127_6177002_13 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000001776 181.0
TLS3_k127_6177002_14 FR47-like protein K16704 - 2.3.1.210 0.0000000000000000000000000000001193 134.0
TLS3_k127_6177002_15 membrane - - - 0.0000003879 63.0
TLS3_k127_6177002_16 Predicted membrane protein (DUF2079) K07778 - 2.7.13.3 0.000003287 60.0
TLS3_k127_6177002_17 carbamoyl transferase, NodU family K00612 - - 0.000003578 49.0
TLS3_k127_6177002_18 Predicted membrane protein (DUF2079) K07778 - 2.7.13.3 0.000004874 59.0
TLS3_k127_6177002_19 protein phosphatase 1, regulatory subunit 16A K17458,K17459 GO:0002009,GO:0002165,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0007275,GO:0007444,GO:0007472,GO:0007476,GO:0007552,GO:0007560,GO:0008150,GO:0008157,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0010921,GO:0017020,GO:0019208,GO:0019220,GO:0019222,GO:0019888,GO:0019899,GO:0019902,GO:0019903,GO:0030234,GO:0031323,GO:0031399,GO:0032268,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0035303,GO:0035304,GO:0043666,GO:0044424,GO:0044444,GO:0044464,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051174,GO:0051246,GO:0051336,GO:0060255,GO:0060429,GO:0060562,GO:0065007,GO:0065009,GO:0080090,GO:0098772 - 0.0000126 52.0
TLS3_k127_6177002_2 Involved in galactofuranosyl biosynthesis converts UDO-GlcP to UDP-GalP catalytic activity UDP- glucopyranose UDP-galactopyranose - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 511.0
TLS3_k127_6177002_20 - - - - 0.00001303 50.0
TLS3_k127_6177002_21 membrane protein (DUF2079) - - - 0.00003515 56.0
TLS3_k127_6177002_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00066,K02472,K02474,K13015 - 1.1.1.132,1.1.1.136,1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 454.0
TLS3_k127_6177002_4 Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate K02805 GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0005976,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016740,GO:0016769,GO:0019180,GO:0019842,GO:0030170,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046378,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901576 2.6.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 442.0
TLS3_k127_6177002_5 PFAM Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 394.0
TLS3_k127_6177002_6 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 373.0
TLS3_k127_6177002_7 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 357.0
TLS3_k127_6177002_8 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 287.0
TLS3_k127_6177002_9 chaperone DnaJ K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006166 281.0
TLS3_k127_6190584_0 Multifunctional fusion protein K14164 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 3.857e-223 726.0
TLS3_k127_6190584_1 AAA domain K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 407.0
TLS3_k127_6190584_2 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000007633 235.0
TLS3_k127_6190584_3 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000000005653 137.0
TLS3_k127_6190584_4 protein trimerization - - - 0.0000000000000000006826 98.0
TLS3_k127_6190584_5 PFAM RES domain - - - 0.000000000000002624 81.0
TLS3_k127_6190584_6 Protein of unknown function (DUF2384) - - - 0.000000001167 65.0
TLS3_k127_6208822_0 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.913e-220 705.0
TLS3_k127_6208822_1 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 295.0
TLS3_k127_6208822_10 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000008458 104.0
TLS3_k127_6208822_11 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000001478 83.0
TLS3_k127_6208822_2 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005406 273.0
TLS3_k127_6208822_3 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000001163 252.0
TLS3_k127_6208822_4 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000003425 234.0
TLS3_k127_6208822_5 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000000000000003492 211.0
TLS3_k127_6208822_6 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000003944 209.0
TLS3_k127_6208822_7 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000254 192.0
TLS3_k127_6208822_8 PhoQ Sensor - - - 0.00000000000000000000000003098 125.0
TLS3_k127_6208822_9 rRNA processing K02834 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000004747 108.0
TLS3_k127_6217791_0 addiction module antidote protein HigA K07110,K21686 - - 0.000000000000000000000000000000000000000000002516 175.0
TLS3_k127_6217791_1 Bacterial type II/III secretion system short domain K02453 - - 0.000000000000000000000000000000000000000004764 169.0
TLS3_k127_6217791_2 Domain of unknown function (DUF2341) - - - 0.00000000000000000000000000000000001141 154.0
TLS3_k127_6217791_3 PIN domain - - - 0.000000000000000000000005012 106.0
TLS3_k127_6217791_4 RelE toxin of RelE / RelB toxin-antitoxin system - - - 0.00000000000000002308 87.0
TLS3_k127_6217791_5 SpoVT / AbrB like domain - - - 0.00000006845 58.0
TLS3_k127_6217791_6 Helix-turn-helix XRE-family like proteins K07726 - - 0.0000002453 57.0
TLS3_k127_6217791_7 Helix-turn-helix domain - - - 0.000001558 55.0
TLS3_k127_6226276_0 SRP-dependent cotranslational protein targeting to membrane K03110 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 323.0
TLS3_k127_6226276_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007092 329.0
TLS3_k127_6226276_2 Thioredoxin K03671 - - 0.0000000000000000000000000000000000001366 145.0
TLS3_k127_6226276_3 COG2143 Thioredoxin-related protein - - - 0.0000000000000000001609 96.0
TLS3_k127_6235752_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000004915 115.0
TLS3_k127_6238803_0 Toxin with a conserved tryptophan and TIP tripeptide motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 360.0
TLS3_k127_6238803_1 2 iron, 2 sulfur cluster binding K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002769 271.0
TLS3_k127_6238803_2 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000003603 211.0
TLS3_k127_6238803_4 chlorophyll binding - - - 0.000000000000000000000000000000002047 151.0
TLS3_k127_6238803_5 PFAM Ankyrin repeat - - - 0.00000000419 68.0
TLS3_k127_6250353_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000004803 246.0
TLS3_k127_6251100_0 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 2.98e-205 669.0
TLS3_k127_6251100_1 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 477.0
TLS3_k127_6251100_10 Tetratricopeptide repeat - - - 0.0000000000002227 82.0
TLS3_k127_6251100_11 - - - - 0.000008272 57.0
TLS3_k127_6251100_13 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03428,K07003,K15984 - 2.1.1.11,2.1.1.242 0.0001816 53.0
TLS3_k127_6251100_2 Pectate lyase K01728,K21606 - 3.2.1.202,4.2.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 432.0
TLS3_k127_6251100_3 3-demethylubiquinone-9 3-O-methyltransferase activity K15257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001082 246.0
TLS3_k127_6251100_4 - - - - 0.00000000000000000000000000000000000000000000000003961 196.0
TLS3_k127_6251100_5 rRNA (adenine-C2-)-methyltransferase activity K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000005106 175.0
TLS3_k127_6251100_6 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000000000000000000000001275 143.0
TLS3_k127_6251100_7 luxR family - - - 0.0000000000000000000000000000000002192 139.0
TLS3_k127_6251100_9 methyltransferase - - - 0.000000000000000000007215 105.0
TLS3_k127_6257844_0 TIGRFAM phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 588.0
TLS3_k127_6257844_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 501.0
TLS3_k127_6257844_10 - - - - 0.000000000000000001471 98.0
TLS3_k127_6257844_11 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000007601 66.0
TLS3_k127_6257844_12 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243 - 3.2.2.9 0.00000001169 64.0
TLS3_k127_6257844_14 Belongs to the Smg family K03747 - - 0.0001443 53.0
TLS3_k127_6257844_2 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity K01923,K01945,K03566 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 409.0
TLS3_k127_6257844_3 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001092 271.0
TLS3_k127_6257844_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000001257 241.0
TLS3_k127_6257844_5 Disulphide isomerase - - - 0.000000000000000000000000000000000000000000000000004199 184.0
TLS3_k127_6257844_6 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000009846 166.0
TLS3_k127_6257844_7 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000004886 142.0
TLS3_k127_6257844_8 cell envelope organization K05807,K08309 - - 0.00000000000000000000000000000000089 142.0
TLS3_k127_6257844_9 Outer membrane lipoprotein - - - 0.0000000000000000000004768 107.0
TLS3_k127_6265438_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 333.0
TLS3_k127_6265438_1 protein-glutamate methylesterase activity K03412,K03413 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000001271 137.0
TLS3_k127_6265438_2 COG0643 Chemotaxis protein histidine kinase and related kinases K03407 - 2.7.13.3 0.00000000000000000000000000000009936 144.0
TLS3_k127_6265438_3 PALM domain HD hydrolase domain and K09749 - - 0.0000000000000000000000000000001539 143.0
TLS3_k127_6265438_4 response regulator K03413 - - 0.000000000000000000000000000000744 127.0
TLS3_k127_6265438_5 Two component signalling adaptor domain - - - 0.000000000000000000000001531 109.0
TLS3_k127_6265438_6 PFAM TonB-dependent receptor, plug K02014,K16089 - - 0.0000000000000007121 82.0
TLS3_k127_626763_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 439.0
TLS3_k127_626763_1 lipopolysaccharide-transporting ATPase activity K07091,K11720 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 400.0
TLS3_k127_626763_10 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000005302 193.0
TLS3_k127_626763_11 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000008413 175.0
TLS3_k127_626763_2 PFAM peptidase U62 modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 376.0
TLS3_k127_626763_3 carboxylic acid catabolic process K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 315.0
TLS3_k127_626763_4 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006887 295.0
TLS3_k127_626763_5 metallocarboxypeptidase activity K14054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001349 274.0
TLS3_k127_626763_6 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000007604 246.0
TLS3_k127_626763_7 lipopolysaccharide-transporting ATPase activity K11720 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0033036,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000009648 245.0
TLS3_k127_626763_8 tRNA wobble adenosine to inosine editing K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000000001846 216.0
TLS3_k127_626763_9 GGDEF domain - - - 0.00000000000000000000000000000000000000000000002897 192.0
TLS3_k127_6275356_0 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 295.0
TLS3_k127_6275356_1 Pfam Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000009135 158.0
TLS3_k127_6275356_2 O-methyltransferase activity - - - 0.00000000000000000000000000000001774 138.0
TLS3_k127_6275356_3 polysaccharide deacetylase - - - 0.0000000000000000000000001412 122.0
TLS3_k127_6275356_4 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000001108 103.0
TLS3_k127_6275356_5 - - - - 0.00000000000000000000507 108.0
TLS3_k127_6275356_7 protein involved in methicillin resistance - - - 0.000006015 58.0
TLS3_k127_6278120_0 AcrB/AcrD/AcrF family K07787 - - 0.0 1727.0
TLS3_k127_6278120_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 456.0
TLS3_k127_6278120_2 Belongs to the CarB family K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 361.0
TLS3_k127_6278120_3 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 327.0
TLS3_k127_6278120_4 PFAM MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000134 121.0
TLS3_k127_6278120_5 Putative transposase - - - 0.00000000000000000000001516 101.0
TLS3_k127_6278120_6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000008232 87.0
TLS3_k127_6278120_8 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00008589 53.0
TLS3_k127_6292051_0 Acyl-CoA dehydrogenase, C-terminal domain K06446 - - 3.978e-261 817.0
TLS3_k127_6292051_1 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 2.455e-226 723.0
TLS3_k127_6292051_10 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000004706 214.0
TLS3_k127_6292051_11 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000004779 211.0
TLS3_k127_6292051_12 serine threonine protein kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.0000000000000000000000000000000000000000000000000002488 207.0
TLS3_k127_6292051_13 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000004079 183.0
TLS3_k127_6292051_15 2 iron, 2 sulfur cluster binding K07058 - - 0.000000000000000000000004446 117.0
TLS3_k127_6292051_16 Sel1-like repeats. K07126 - - 0.00000000000000000000003354 114.0
TLS3_k127_6292051_17 Rhodanese Homology Domain - - - 0.0000000000000000000007719 102.0
TLS3_k127_6292051_18 - - - - 0.000000002064 64.0
TLS3_k127_6292051_19 Nacht domain - - - 0.00000001383 67.0
TLS3_k127_6292051_2 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 8.651e-215 696.0
TLS3_k127_6292051_20 chaperone-mediated protein folding - - - 0.000000155 64.0
TLS3_k127_6292051_21 COG0457 FOG TPR repeat - - - 0.000003478 59.0
TLS3_k127_6292051_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 424.0
TLS3_k127_6292051_4 - K19295 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 423.0
TLS3_k127_6292051_5 PFAM NAD-dependent epimerase dehydratase K01784,K10011 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 393.0
TLS3_k127_6292051_6 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002317 280.0
TLS3_k127_6292051_7 Histidine kinase K00936 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000001928 247.0
TLS3_k127_6292051_8 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000009113 231.0
TLS3_k127_6292051_9 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000001741 228.0
TLS3_k127_6303612_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 380.0
TLS3_k127_6303612_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 350.0
TLS3_k127_6303612_2 aminoacyl-tRNA hydrolase activity K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000002726 173.0
TLS3_k127_6303612_3 Belongs to the PAPS reductase family. CysH subfamily K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000001931 156.0
TLS3_k127_6303612_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000005785 110.0
TLS3_k127_6303612_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919,K02528,K16924 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.1.1.182,2.7.1.148 0.000000000000000001843 91.0
TLS3_k127_6303612_6 Rrf2 family transcriptional regulator K17472 GO:0001047,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0032991,GO:0032993,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044212,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0071840,GO:0097159,GO:1901363 - 0.000000000000000008566 88.0
TLS3_k127_6303612_7 C4-type zinc ribbon domain K07164 - - 0.0000000000000000146 91.0
TLS3_k127_6303612_8 ThiF family K21029 - 2.7.7.80 0.0000000001133 63.0
TLS3_k127_6313661_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 9.025e-280 883.0
TLS3_k127_6313661_1 alpha amylase, catalytic K01236 - 3.2.1.141 2.574e-207 662.0
TLS3_k127_6313661_10 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.00000000000000000000000002365 117.0
TLS3_k127_6313661_2 MMPL family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 494.0
TLS3_k127_6313661_3 Aminotransferase K03430 - 2.6.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 441.0
TLS3_k127_6313661_4 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 372.0
TLS3_k127_6313661_5 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 337.0
TLS3_k127_6313661_6 - - - - 0.0000000000000000000000000000000000000000000207 181.0
TLS3_k127_6313661_7 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000001135 142.0
TLS3_k127_6313661_8 phosphoglycerate mutase - - - 0.0000000000000000000000000000000002862 141.0
TLS3_k127_6313661_9 Lysine methyltransferase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010565,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018023,GO:0018193,GO:0018205,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031974,GO:0031998,GO:0031999,GO:0032259,GO:0036211,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0043467,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045833,GO:0045922,GO:0046320,GO:0046322,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050994,GO:0050995,GO:0051341,GO:0051354,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1904732,GO:1904733,GO:1904735,GO:1904736 - 0.0000000000000000000000000000005813 134.0
TLS3_k127_6316880_0 Collagenase K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 323.0
TLS3_k127_6316880_1 - - - - 0.0000000000000000003467 101.0
TLS3_k127_6316880_2 repeat-containing protein - - - 0.00001051 59.0
TLS3_k127_6336943_0 ferrous iron transmembrane transporter activity K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 537.0
TLS3_k127_6336943_1 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K02440,K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 407.0
TLS3_k127_6336943_10 Aromatic amino acid lyase - - - 0.000000000000004897 79.0
TLS3_k127_6336943_11 SigmaW regulon antibacterial - - - 0.00000001262 56.0
TLS3_k127_6336943_12 FeoA K04758 - - 0.0000001919 57.0
TLS3_k127_6336943_13 - - - - 0.000001692 56.0
TLS3_k127_6336943_14 - - - - 0.00002471 48.0
TLS3_k127_6336943_2 Aminopeptidase I zinc metalloprotease (M18) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008817 364.0
TLS3_k127_6336943_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 308.0
TLS3_k127_6336943_4 Phenolic acid decarboxylase (PAD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001961 245.0
TLS3_k127_6336943_5 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000005476 183.0
TLS3_k127_6336943_6 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000001974 188.0
TLS3_k127_6336943_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000002287 157.0
TLS3_k127_6336943_8 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000000001427 155.0
TLS3_k127_6336943_9 addiction module antidote protein HigA K07110,K21686 - - 0.0000000000000000000000000000001575 134.0
TLS3_k127_6341452_0 phosphoenolpyruvate carboxykinase (diphosphate) activity K20370 - 4.1.1.38 9.861e-228 724.0
TLS3_k127_6341452_1 TIGRFAM RarD protein K05786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005939 251.0
TLS3_k127_6341452_2 Type VI secretion system effector, Hcp K11903 - - 0.00000000000000000000000000000000000000000000000000000000000001082 220.0
TLS3_k127_6341452_3 PIF1-like helicase - - - 0.00000000000000000000000000000000000004127 144.0
TLS3_k127_6341452_4 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.0000000000000000000000000000000000003242 143.0
TLS3_k127_6341452_5 carboxylic ester hydrolase activity K01259 - 3.4.11.5 0.00000000000000000000000000000000000449 143.0
TLS3_k127_6341452_6 transcription regulator containing HTH domain K18831 - - 0.00000000000000000000000000000000001881 138.0
TLS3_k127_6341452_7 SnoaL-like domain - - - 0.000000000000000000000000003918 116.0
TLS3_k127_6341452_8 - - - - 0.0000000000001427 82.0
TLS3_k127_6352196_0 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000085 284.0
TLS3_k127_6352196_1 Branched-chain amino acid transport system / permease component K01997,K11960 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000132 269.0
TLS3_k127_6353274_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 529.0
TLS3_k127_6353274_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000002811 149.0
TLS3_k127_6355184_0 Domain of Unknown Function (DUF1206) - - - 0.0000000000000000000000000000000000002858 151.0
TLS3_k127_6355184_1 Beta-lactamase - - - 0.0000000000000000000004614 101.0
TLS3_k127_6358513_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.161e-201 657.0
TLS3_k127_6358513_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 533.0
TLS3_k127_6358513_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000001841 263.0
TLS3_k127_6358513_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000004686 167.0
TLS3_k127_6358513_4 Pyridoxamine 5'-phosphate oxidase like - - - 0.000000000000000000000000000000000000000001139 163.0
TLS3_k127_6359350_0 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 371.0
TLS3_k127_6359350_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 309.0
TLS3_k127_6359350_10 Transposase - - - 0.000000000000006906 82.0
TLS3_k127_6359350_11 UbiA prenyltransferase family - - - 0.000000000001547 78.0
TLS3_k127_6359350_12 - - - - 0.000000002546 70.0
TLS3_k127_6359350_13 Histidine kinase K07649 - 2.7.13.3 0.00000002787 66.0
TLS3_k127_6359350_14 CAAX protease self-immunity K07052 - - 0.0000001507 62.0
TLS3_k127_6359350_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000003027 239.0
TLS3_k127_6359350_3 - - - - 0.000000000000000000000000000000000000000000000003543 185.0
TLS3_k127_6359350_5 MgtC family K07507 - - 0.0000000000000000000000000000000000008557 149.0
TLS3_k127_6359350_6 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.000000000000000000000000007682 112.0
TLS3_k127_6359350_7 Domains HisKA, HATPase_c - - - 0.000000000000000000001519 110.0
TLS3_k127_6359350_8 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000007179 108.0
TLS3_k127_6359350_9 helix_turn_helix, Lux Regulon - - - 0.0000000000000000001998 98.0
TLS3_k127_6402357_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 6.568e-295 917.0
TLS3_k127_6402357_1 - - - - 4.506e-206 665.0
TLS3_k127_6402357_2 Belongs to the ompA family K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003612 273.0
TLS3_k127_6402357_3 - K07283 - - 0.00000000000000000000000000000000000000000000000000003361 199.0
TLS3_k127_6402357_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000004032 176.0
TLS3_k127_6402357_5 small membrane protein - - - 0.00000000000000000000000000005473 120.0
TLS3_k127_6402357_6 YceI-like domain - - - 0.0000001234 56.0
TLS3_k127_6440949_0 Transcriptional accessory protein K06959 - - 8.664e-225 724.0
TLS3_k127_6440949_1 Alpha-1,2-mannosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 409.0
TLS3_k127_6440949_2 Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP) K00209 - 1.3.1.44,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007923 270.0
TLS3_k127_6440949_3 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008864 249.0
TLS3_k127_6440949_4 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000004728 222.0
TLS3_k127_6452410_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 539.0
TLS3_k127_6452410_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 462.0
TLS3_k127_6452410_2 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 371.0
TLS3_k127_6452410_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 324.0
TLS3_k127_6452410_4 Domain of Unknown Function (DUF349) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002189 297.0
TLS3_k127_6452410_5 COG1230 Co Zn Cd efflux system component K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000009041 250.0
TLS3_k127_6452410_6 COGs COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000001246 198.0
TLS3_k127_6452410_7 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000001829 184.0
TLS3_k127_6452410_8 Flagellar hook protein flgE K02390 - - 0.00000000000005608 86.0
TLS3_k127_6452410_9 basal body rod protein K02390 - - 0.000102 55.0
TLS3_k127_6505192_0 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 445.0
TLS3_k127_6505192_1 Protein of unknown function, DUF255 K04084,K06888 - 1.8.1.8 0.0000000001217 63.0
TLS3_k127_6505192_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000002106 68.0
TLS3_k127_6505192_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000005405 59.0
TLS3_k127_6523433_0 PFAM Adenosylcobinamide amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002538 289.0
TLS3_k127_6523433_1 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000003182 246.0
TLS3_k127_6523433_2 xylan catabolic process K03932 - - 0.000000000000000000000000000000000000000009714 168.0
TLS3_k127_6523433_3 Domain of unknown function (DUF2341) - - - 0.0000000000000000000004291 107.0
TLS3_k127_6523433_4 MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000001949 103.0
TLS3_k127_6523433_5 heme binding - - - 0.0000000000009001 81.0
TLS3_k127_6523433_6 cell adhesion K02024 - - 0.00002471 59.0
TLS3_k127_6523433_7 Belongs to the peptidase S8 family - - - 0.00004282 58.0
TLS3_k127_6523433_8 NlpC/P60 family K21472 - - 0.00008589 53.0
TLS3_k127_6532466_0 cysteine-tRNA ligase activity K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 4.175e-195 618.0
TLS3_k127_6532466_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 554.0
TLS3_k127_6532466_10 Histidine kinase response regulator - - - 0.0000000000000000000000000005564 116.0
TLS3_k127_6532466_11 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000001335 111.0
TLS3_k127_6532466_12 - - - - 0.000000000000000000000001125 108.0
TLS3_k127_6532466_14 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0009721 46.0
TLS3_k127_6532466_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 454.0
TLS3_k127_6532466_3 TIGRFAM SagB-type dehydrogenase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001427 297.0
TLS3_k127_6532466_4 serine-type endopeptidase activity K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000001666 242.0
TLS3_k127_6532466_5 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000008601 223.0
TLS3_k127_6532466_6 HDOD domain - - - 0.00000000000000000000000000000000000000000000000001289 190.0
TLS3_k127_6532466_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000005138 189.0
TLS3_k127_6532466_8 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000004057 152.0
TLS3_k127_6532466_9 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000001511 132.0
TLS3_k127_6545841_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 570.0
TLS3_k127_6545841_1 TIGRFAM DNA topoisomerase III, bacteria and conjugative plasmid K03169 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 436.0
TLS3_k127_6545841_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 328.0
TLS3_k127_6545841_3 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.0000000000000000000000000000000000000000000000000003145 192.0
TLS3_k127_6545841_4 Glycosyl transferases group 1 K13668 - 2.4.1.346 0.00000000000000000000000000000000000934 152.0
TLS3_k127_6545841_5 peptidyl-tyrosine sulfation - - - 0.00000000000004274 84.0
TLS3_k127_6545841_6 3-dehydroquinate dehydratase activity K03785,K13832 GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0042537,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.1.25,4.2.1.10 0.000000005853 66.0
TLS3_k127_6545841_7 recombinase activity K06400 - - 0.0003837 51.0
TLS3_k127_6560258_0 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 335.0
TLS3_k127_6560258_1 IgA Peptidase M64 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003374 293.0
TLS3_k127_6560258_2 lysine 2,3-aminomutase - - - 0.00000000000000000000000000000000000000000007396 163.0
TLS3_k127_6560258_3 Outer membrane protein protective antigen OMA87 - - - 0.000000001034 72.0
TLS3_k127_6636562_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 547.0
TLS3_k127_6636562_1 DNA Topoisomerase IV K02621 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 545.0
TLS3_k127_6636562_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 297.0
TLS3_k127_6636562_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000002701 183.0
TLS3_k127_6654978_0 DEAD DEAH box helicase K03724 - - 0.0 1560.0
TLS3_k127_6654978_1 bacterial-type flagellum-dependent cell motility K02390 GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 597.0
TLS3_k127_6654978_10 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000001858 245.0
TLS3_k127_6654978_11 Predicted membrane protein (DUF2214) K08983 - - 0.000000000000000000000000000000000000000006952 158.0
TLS3_k127_6654978_12 Protein of unknown function (DUF1015) K00262 - 1.4.1.4 0.000000000000000000000000000000000000000008394 169.0
TLS3_k127_6654978_13 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 - - 0.00000000000000000000000000000000000000003508 164.0
TLS3_k127_6654978_14 Protein of unknown function, DUF393 - - - 0.0000000000000000000000000000000000000004138 153.0
TLS3_k127_6654978_15 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0000000000000000000000000000000000000008578 154.0
TLS3_k127_6654978_16 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.00000000000000000000000000000000000003791 154.0
TLS3_k127_6654978_17 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000001797 148.0
TLS3_k127_6654978_18 Protein of unknown function (DUF962) - - - 0.00000000000000000000000000000000006952 139.0
TLS3_k127_6654978_19 ABC superfamily ATP binding cassette transporter ABC protein K01990 - - 0.000000000000000000000000000002694 130.0
TLS3_k127_6654978_2 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 413.0
TLS3_k127_6654978_20 COG3668 Plasmid stabilization system protein - - - 0.00000000000000000000000000001312 121.0
TLS3_k127_6654978_21 Required for flagellar hook formation. May act as a scaffolding protein K02389 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.0000000000000000000000000000526 127.0
TLS3_k127_6654978_22 - - - - 0.00000000000000000000000000007038 121.0
TLS3_k127_6654978_23 Flagellar biosynthetic protein FliR K02421 - - 0.0000000000000000000000001219 117.0
TLS3_k127_6654978_24 PFAM Phage derived protein Gp49-like (DUF891) - - - 0.000000000000000000000004361 103.0
TLS3_k127_6654978_25 phosphoribosyltransferase K07100 - - 0.000000000000000000000007648 109.0
TLS3_k127_6654978_26 Helix-turn-helix domain - - - 0.00000000000000000000003164 104.0
TLS3_k127_6654978_27 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000003458 108.0
TLS3_k127_6654978_28 Role in flagellar biosynthesis K02420 - - 0.00000000000000001431 85.0
TLS3_k127_6654978_29 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000001216 89.0
TLS3_k127_6654978_3 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 381.0
TLS3_k127_6654978_30 - - - - 0.0000000000002157 74.0
TLS3_k127_6654978_31 PFAM flagellar hook-length control K02414 - - 0.00000000008227 75.0
TLS3_k127_6654978_32 Flagellar FlbD family protein K02385 - - 0.000001286 60.0
TLS3_k127_6654978_33 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.0002437 51.0
TLS3_k127_6654978_34 Outer membrane protein beta-barrel domain - - - 0.0004171 51.0
TLS3_k127_6654978_35 COG3190 Flagellar biogenesis protein K02418 - - 0.0004214 50.0
TLS3_k127_6654978_36 MgtE intracellular N domain - - - 0.0008529 50.0
TLS3_k127_6654978_4 Domain of unknown function (DUF4166) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 348.0
TLS3_k127_6654978_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K14189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848 310.0
TLS3_k127_6654978_6 DoxX-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 304.0
TLS3_k127_6654978_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002943 314.0
TLS3_k127_6654978_8 Plays a role in the flagellum-specific transport system K02419 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001495 278.0
TLS3_k127_6654978_9 Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003304 239.0
TLS3_k127_6658638_0 L-malate dehydrogenase activity K00024 GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 365.0
TLS3_k127_6658638_1 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001097 268.0
TLS3_k127_6658638_2 cellulase activity - - - 0.00000000000000000000000000000008377 142.0
TLS3_k127_6699415_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0 2374.0
TLS3_k127_6699415_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 409.0
TLS3_k127_6699415_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000386 237.0
TLS3_k127_6699415_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000003945 233.0
TLS3_k127_6699415_4 protein histidine kinase activity K07315,K07641,K10819,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000348 221.0
TLS3_k127_6699415_5 PFAM glycosyl transferase family 9 - - - 0.000000000000000000000000000000000000000001706 175.0
TLS3_k127_6699415_6 - - - - 0.00000000000000000000001377 114.0
TLS3_k127_6699415_7 nuclear chromosome segregation K03546 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000001559 68.0
TLS3_k127_6699415_8 cheY-homologous receiver domain K02485 - - 0.000000134 60.0
TLS3_k127_6699415_9 PFAM ATP-binding region, ATPase domain protein K02486 - 2.7.13.3 0.0000064 59.0
TLS3_k127_6706643_0 Glucoamylase and related glycosyl hydrolases - - - 3.966e-267 834.0
TLS3_k127_6706643_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 509.0
TLS3_k127_6706643_10 phosphatidate phosphatase activity K00901,K01096,K19302 - 2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.000007447 57.0
TLS3_k127_6706643_2 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 394.0
TLS3_k127_6706643_3 COG5337 Spore coat assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000007333 246.0
TLS3_k127_6706643_4 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000001239 184.0
TLS3_k127_6706643_5 YCII-related domain - - - 0.0000000000000000000000000000009036 125.0
TLS3_k127_6706643_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000008825 115.0
TLS3_k127_6706643_7 PFAM bifunctional deaminase-reductase domain protein - - - 0.0000000000000000000002654 96.0
TLS3_k127_6706643_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000006851 106.0
TLS3_k127_6706643_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000002714 92.0
TLS3_k127_6721684_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007787 314.0
TLS3_k127_6721684_1 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000544 211.0
TLS3_k127_6721684_2 Protein of unknown function (DUF1569) - - - 0.00000000000000000000000000000000000000000000000000000008739 201.0
TLS3_k127_6721684_3 regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose K02099 - - 0.000000000000000000000000000000000000000000000002739 183.0
TLS3_k127_6721684_4 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000004846 127.0
TLS3_k127_6721684_5 Domain of unknown function (DUF1905) - - - 0.00000000000000000000006646 102.0
TLS3_k127_6750135_0 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 481.0
TLS3_k127_6750135_1 Protein of unknown function (DUF4197) - - - 0.00000000000000003295 93.0
TLS3_k127_6750135_2 Protein of unknown function (DUF3570) - - - 0.0000000001675 72.0
TLS3_k127_6762179_0 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 294.0
TLS3_k127_6762179_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000005186 176.0
TLS3_k127_6762179_2 O-Antigen ligase - - - 0.0000000000000000000000007771 120.0
TLS3_k127_6762179_3 Polysaccharide biosynthesis protein K03328 - - 0.000000000000000000000001846 118.0
TLS3_k127_6769998_0 Sulfate permease family K03321 - - 3.803e-238 750.0
TLS3_k127_6769998_1 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 614.0
TLS3_k127_6769998_10 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372,K16363 - 3.5.1.108,4.2.1.59 0.0000000000000000000000002337 111.0
TLS3_k127_6769998_11 Acyl carrier protein - - - 0.0000000000000000001234 91.0
TLS3_k127_6769998_12 NnrS protein - - - 0.00000000000001946 86.0
TLS3_k127_6769998_13 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00009549 48.0
TLS3_k127_6769998_2 epimerase dehydratase K01710,K01784 - 4.2.1.46,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009901 566.0
TLS3_k127_6769998_3 UDP binding domain K00066 - 1.1.1.132 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 539.0
TLS3_k127_6769998_4 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666,K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 481.0
TLS3_k127_6769998_5 NAD+ synthase (glutamine-hydrolyzing) activity K01916 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 432.0
TLS3_k127_6769998_6 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 419.0
TLS3_k127_6769998_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 317.0
TLS3_k127_6769998_8 Aminoglycoside 3-N-acetyltransferase K00662 - 2.3.1.81 0.000000000000000000000000000000000000000000007408 186.0
TLS3_k127_6769998_9 KR domain K10780 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 0.00000000000000000000000000000000000000000003532 175.0
TLS3_k127_6775616_0 RNA polymerase activity K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 452.0
TLS3_k127_6775616_1 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000005274 189.0
TLS3_k127_6775616_2 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000001524 176.0
TLS3_k127_6775616_3 mitochondrial genome maintenance K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.00000000000000000000000000000000000000004658 157.0
TLS3_k127_6775616_4 positive regulation of growth rate K01449 - 3.5.1.28 0.00000000000000000007207 102.0
TLS3_k127_6775616_5 excinuclease ABC activity K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000002228 90.0
TLS3_k127_6775616_6 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000005627 72.0
TLS3_k127_6775616_7 Pfam:DUF955 - - - 0.0001677 48.0
TLS3_k127_6804744_0 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 497.0
TLS3_k127_6804744_1 Spore coat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 410.0
TLS3_k127_6804744_10 cell wall binding - - - 0.0000000000001098 86.0
TLS3_k127_6804744_11 Cellulose Binding Domain Type IV K01219 - 3.2.1.81 0.000000005478 71.0
TLS3_k127_6804744_12 Bacterial Ig-like domain 2 - - - 0.0000001104 66.0
TLS3_k127_6804744_13 uroporphyrinogen III synthase K01719 - 4.2.1.75 0.0000001137 64.0
TLS3_k127_6804744_14 Cadherin-like beta sandwich domain - - - 0.0000001985 64.0
TLS3_k127_6804744_15 PFAM peptidase S8 and S53 subtilisin kexin sedolisin K08651 - 3.4.21.66 0.0007377 53.0
TLS3_k127_6804744_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 333.0
TLS3_k127_6804744_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000004508 247.0
TLS3_k127_6804744_4 FG-GAP repeat - - - 0.00000000000000000000000000000000000000000000000000000000003457 220.0
TLS3_k127_6804744_5 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000001517 174.0
TLS3_k127_6804744_6 Mycoplasma protein of unknown function, DUF285 - - - 0.00000000000000000000000002377 128.0
TLS3_k127_6804744_7 YbaB/EbfC DNA-binding family K09747 - - 0.00000000000000000000000008817 109.0
TLS3_k127_6804744_8 metallopeptidase activity K01186 - 3.2.1.18 0.0000000000000000000001014 116.0
TLS3_k127_6804744_9 ABC-type transport system involved in cytochrome c biogenesis, permease component K02497 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 - 0.00000000000002113 83.0
TLS3_k127_6857426_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.258e-209 661.0
TLS3_k127_6857426_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009025 452.0
TLS3_k127_6857426_2 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 409.0
TLS3_k127_6857426_3 phenazine biosynthesis K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 299.0
TLS3_k127_6857426_4 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000002889 209.0
TLS3_k127_6857426_5 PEP-CTERM motif - - - 0.0000000000000000000000000000000006175 139.0
TLS3_k127_6857426_6 Nucleoside H+ symporter K05820 - - 0.0000001679 63.0
TLS3_k127_6857426_7 - - - - 0.0000006183 58.0
TLS3_k127_6869363_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 612.0
TLS3_k127_6869363_1 - - - - 0.0000002 64.0
TLS3_k127_6877376_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000007729 236.0
TLS3_k127_6877376_1 Predicted membrane protein (DUF2157) - - - 0.000000000000000000000000000000000000000000000000000000000000001119 231.0
TLS3_k127_6877376_2 - - - - 0.000000000000000000000000000000000000000004217 169.0
TLS3_k127_6877376_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000003502 124.0
TLS3_k127_6877376_4 tigr02147 - - - 0.00000000000000000000000000001541 128.0
TLS3_k127_6877376_5 arsR family transcriptional regulator - - - 0.000000000000000000000001264 109.0
TLS3_k127_6893534_0 hydrolase activity, hydrolyzing O-glycosyl compounds K00700,K07214,K16147 - 2.4.1.18,2.4.99.16 1.272e-196 635.0
TLS3_k127_6893534_1 glycogen (starch) synthase activity K16148 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 556.0
TLS3_k127_6893534_10 Stress responsive A/B Barrel Domain - - - 0.000000000000000000000000006937 119.0
TLS3_k127_6893534_11 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000001521 117.0
TLS3_k127_6893534_13 pathogenesis - - - 0.0000000000000008384 89.0
TLS3_k127_6893534_14 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000007886 59.0
TLS3_k127_6893534_15 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000003956 64.0
TLS3_k127_6893534_2 Glycosyltransferase Family 4 K14335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 372.0
TLS3_k127_6893534_3 exoribonuclease II activity K12573,K12585 GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 377.0
TLS3_k127_6893534_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002077 293.0
TLS3_k127_6893534_5 Uncharacterized protein conserved in bacteria (DUF2334) K06986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002365 273.0
TLS3_k127_6893534_6 TIGRFAM phosphoenolpyruvate-protein phosphotransferase K08484 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000001541 282.0
TLS3_k127_6893534_7 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000003367 240.0
TLS3_k127_6893534_8 - - - - 0.00000000000000000000000000000000000000000000002377 184.0
TLS3_k127_6893534_9 Two component regulator propeller - - - 0.00000000000000000000000000000001271 141.0
TLS3_k127_6899036_0 PAS domain K13924 - 2.1.1.80,3.1.1.61 2.848e-243 807.0
TLS3_k127_6899036_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 302.0
TLS3_k127_6899036_3 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000002291 168.0
TLS3_k127_6899036_4 converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000000000000000000000004403 155.0
TLS3_k127_6899036_5 Alpha-L-arabinofuranosidase C-terminus - - - 0.000000000000000000000000000000000007823 158.0
TLS3_k127_6899036_6 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000001569 119.0
TLS3_k127_6899036_7 Parallel beta-helix repeats - - - 0.0000000000000000000002962 114.0
TLS3_k127_6899036_8 alpha-L-arabinofuranosidase - - - 0.0000000001954 71.0
TLS3_k127_6900002_0 Aromatic amino acid lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002766 248.0
TLS3_k127_6900002_1 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003576 243.0
TLS3_k127_6900002_2 Putative esterase K07214 - - 0.00000000000000000000000000000000000000000000000001403 194.0
TLS3_k127_6900002_3 Transposase domain (DUF772) K07481 - - 0.0000000000000000000000000563 112.0
TLS3_k127_6900002_4 SPTR Transposase IS4 family protein - - - 0.00000000000007749 79.0
TLS3_k127_6900002_5 CHAP domain - - - 0.0006137 50.0
TLS3_k127_6906372_0 Protein of unknown function (DUF3641) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 357.0
TLS3_k127_6906372_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 312.0
TLS3_k127_6906372_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000001153 141.0
TLS3_k127_6906372_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000001846 100.0
TLS3_k127_6906372_4 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.000000000001389 76.0
TLS3_k127_6906372_5 - - - - 0.000000002042 68.0
TLS3_k127_6906372_6 Transmembrane anti-sigma factor - - - 0.00006941 51.0
TLS3_k127_6911909_0 PFAM Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 4.377e-196 621.0
TLS3_k127_6911909_1 TIGRFAM oligoendopeptidase, M3 family K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 550.0
TLS3_k127_6911909_10 Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle K00564 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.172 0.0000000000000000000000000472 125.0
TLS3_k127_6911909_11 - - - - 0.00000000000000005668 96.0
TLS3_k127_6911909_12 photosynthesis - - - 0.000000000000006846 87.0
TLS3_k127_6911909_2 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 512.0
TLS3_k127_6911909_3 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 529.0
TLS3_k127_6911909_4 transposition, DNA-mediated K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002781 279.0
TLS3_k127_6911909_5 rRNA methyltransferase activity K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000005245 244.0
TLS3_k127_6911909_6 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.000000000000000000000000000000000000000000000000000000000000183 222.0
TLS3_k127_6911909_7 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000002786 174.0
TLS3_k127_6911909_8 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000004803 145.0
TLS3_k127_6911909_9 long-chain fatty acid transporting porin activity K02014 - - 0.0000000000000000000000000002629 128.0
TLS3_k127_6924630_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 2.168e-208 662.0
TLS3_k127_6927865_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 376.0
TLS3_k127_6927865_1 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 334.0
TLS3_k127_6927865_2 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005169 326.0
TLS3_k127_6927865_3 lipase activity K15349 - - 0.000000000000000000000000000000000000000001338 172.0
TLS3_k127_6927865_4 Belongs to the glycosyl hydrolase 43 family - - - 0.0000000000000000000000000000000002633 151.0
TLS3_k127_6927865_5 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000002702 112.0
TLS3_k127_6927865_6 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000002403 96.0
TLS3_k127_6927865_7 - - - - 0.00000000000000000001796 100.0
TLS3_k127_6927865_8 penicillin - - - 0.000000000000000001668 100.0
TLS3_k127_6940064_0 plasmid maintenance K03496 GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 297.0
TLS3_k127_6940064_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000008209 231.0
TLS3_k127_6940064_10 Kdo2-lipid A biosynthetic process K02517,K20543,K22311 - 2.3.1.241,2.3.1.265 0.00000001884 66.0
TLS3_k127_6940064_12 Ribonuclease P - - - 0.000006405 56.0
TLS3_k127_6940064_2 Belongs to the ParB family K03497 GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000002041 207.0
TLS3_k127_6940064_3 Membrane proteins related to metalloendopeptidases K21471 - - 0.00000000000000000000000001671 119.0
TLS3_k127_6940064_4 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000503 104.0
TLS3_k127_6940064_5 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000006437 97.0
TLS3_k127_6940064_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.00000000000000000002319 97.0
TLS3_k127_6940064_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000002326 92.0
TLS3_k127_6940064_8 Could be involved in insertion of integral membrane proteins into the membrane K03217,K08998 - - 0.0000000000000001035 86.0
TLS3_k127_6940064_9 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000003374 79.0
TLS3_k127_6940580_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009308 481.0
TLS3_k127_6940580_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 436.0
TLS3_k127_6940580_10 intermembrane phospholipid transfer K07323 - - 0.00000000000000000000000000000000000000127 156.0
TLS3_k127_6940580_11 tRNA threonylcarbamoyladenosine modification K06925,K07102 - 2.7.1.221 0.00000000000000000000000000000009042 129.0
TLS3_k127_6940580_12 MlaD protein - - - 0.0000000000000000000000000000003504 134.0
TLS3_k127_6940580_13 Outer membrane efflux protein - - - 0.000000000000000000000000000004727 137.0
TLS3_k127_6940580_14 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000000000000000000001184 123.0
TLS3_k127_6940580_15 transferase activity, transferring glycosyl groups - - - 0.000001643 60.0
TLS3_k127_6940580_2 PglZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 398.0
TLS3_k127_6940580_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 331.0
TLS3_k127_6940580_5 Integral membrane sensor signal transduction histidine kinase K07709,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 309.0
TLS3_k127_6940580_6 serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000002623 259.0
TLS3_k127_6940580_7 ATPase activity K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007957 256.0
TLS3_k127_6940580_8 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000003119 221.0
TLS3_k127_6940580_9 ABC-type transport auxiliary lipoprotein component - - - 0.000000000000000000000000000000000000000000001278 187.0
TLS3_k127_6941408_0 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 340.0
TLS3_k127_6941408_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000006597 244.0
TLS3_k127_6941408_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000004172 149.0
TLS3_k127_6941408_3 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000002875 140.0
TLS3_k127_6941408_4 tetR family - - - 0.000000000000000000000000000001204 130.0
TLS3_k127_6941408_5 Tyrosine protein kinase - - - 0.000000000000000000000000042 126.0
TLS3_k127_6941408_6 polysaccharide export - - - 0.0000000000004567 78.0
TLS3_k127_6941408_7 Glycosyl transferases group 1 - - - 0.0000002472 59.0
TLS3_k127_6961029_0 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 387.0
TLS3_k127_6961029_1 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000004851 137.0
TLS3_k127_6961029_2 replication factor c K02341,K02343,K09384 - 2.7.7.7 0.000000000000000000000000000004075 135.0
TLS3_k127_6961029_3 Peptidase, M23 K21471 - - 0.0000000000000000000000007883 118.0
TLS3_k127_6961029_4 cell division K09811,K09812 GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976 - 0.00000000000000000002591 102.0
TLS3_k127_6972933_0 COG0553 Superfamily II DNA RNA - - - 3.64e-266 847.0
TLS3_k127_6972933_1 PFAM Blue (type 1) copper domain K09992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 313.0
TLS3_k127_6972933_2 SWIM zinc finger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001144 256.0
TLS3_k127_6972933_3 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000002408 153.0
TLS3_k127_6972933_4 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000003489 149.0
TLS3_k127_6972933_5 addiction module antidote protein HigA K07110,K21686 - - 0.0000000000000000000000000000002253 135.0
TLS3_k127_6973503_0 entry into host K13735 - - 0.000000002802 71.0
TLS3_k127_6981179_0 prolyl-tRNA aminoacylation K01881 - 6.1.1.15 1.062e-208 664.0
TLS3_k127_6981179_1 of the beta-lactamase superfamily I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006606 255.0
TLS3_k127_6981179_2 serine-type D-Ala-D-Ala carboxypeptidase activity K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000008452 199.0
TLS3_k127_6981179_3 SprA-related family - - - 0.000000000000003105 81.0
TLS3_k127_6997703_0 Carbamoyl-phosphate synthetase large chain domain protein K01941 - 6.3.4.6 0.0 1527.0
TLS3_k127_6997703_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 423.0
TLS3_k127_6997703_2 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 410.0
TLS3_k127_6997703_3 abc transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 374.0
TLS3_k127_6997703_4 urea carboxylase-associated protein 1 K09967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 344.0
TLS3_k127_6997703_5 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 287.0
TLS3_k127_6997703_6 Domain of unknown function (DUF1989) K09967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 284.0
TLS3_k127_6997703_7 DoxX K15977 - - 0.00000000000000000000000000000000000001464 151.0
TLS3_k127_6997703_8 Transcriptional regulator - - - 0.0000000000000000000001255 103.0
TLS3_k127_7000046_0 glycosyl transferase group 1 - - - 1.073e-244 788.0
TLS3_k127_7000046_1 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 578.0
TLS3_k127_7000046_2 PFAM Glycoside hydrolase 15-related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005159 299.0
TLS3_k127_7000046_3 Membrane dipeptidase (Peptidase family M19) - - - 0.00000000000000009614 95.0
TLS3_k127_7005059_0 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 607.0
TLS3_k127_7005059_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009795 493.0
TLS3_k127_7005059_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009862 477.0
TLS3_k127_7005059_3 ATPase (AAA superfamily K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 447.0
TLS3_k127_7005059_4 diaminopimelate decarboxylase activity K13747 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042401,GO:0042710,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044010,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044764,GO:0045312,GO:0046204,GO:0046983,GO:0048037,GO:0050662,GO:0051704,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.96 0.0000000000000000000000000000000000000000000000002886 183.0
TLS3_k127_7005059_5 Transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000002068 152.0
TLS3_k127_7005059_6 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000166 83.0
TLS3_k127_701041_0 threonyl-tRNA aminoacylation K01868 GO:0000166,GO:0000900,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004812,GO:0004829,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006435,GO:0006446,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0017076,GO:0017148,GO:0019222,GO:0019538,GO:0019752,GO:0030371,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032553,GO:0032555,GO:0032559,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045182,GO:0045947,GO:0046483,GO:0046872,GO:0046914,GO:0048027,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090079,GO:0090304,GO:0097159,GO:0097367,GO:0106074,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113 6.1.1.3 1.637e-235 745.0
TLS3_k127_701041_1 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 560.0
TLS3_k127_701041_10 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000001652 167.0
TLS3_k127_701041_11 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.000000000000000000000000000000000000000004596 164.0
TLS3_k127_701041_12 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000000000000000002728 150.0
TLS3_k127_701041_13 translation initiation factor activity K02520 GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - 0.000000000000000000000000000000000005574 139.0
TLS3_k127_701041_14 Urease alpha-subunit, N-terminal domain K01428 - 3.5.1.5 0.00000000000000000000000000000000003773 136.0
TLS3_k127_701041_15 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000001321 133.0
TLS3_k127_701041_16 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000003587 137.0
TLS3_k127_701041_17 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935,K02169 - 2.1.1.197,6.3.3.3 0.00000000000000001013 96.0
TLS3_k127_701041_18 homolog of gamma-carboxymuconolactone decarboxylase subunit - - - 0.0000000004933 71.0
TLS3_k127_701041_2 ADP-glyceromanno-heptose 6-epimerase activity K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 511.0
TLS3_k127_701041_20 WYL domain - - - 0.00002653 56.0
TLS3_k127_701041_21 antisigma factor binding K06378 - - 0.0003457 48.0
TLS3_k127_701041_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 481.0
TLS3_k127_701041_4 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 345.0
TLS3_k127_701041_5 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 296.0
TLS3_k127_701041_6 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000009746 272.0
TLS3_k127_701041_7 quinolinate catabolic process K00278,K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 1.4.3.16,2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000737 266.0
TLS3_k127_701041_8 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000000000000000000000001292 214.0
TLS3_k127_701041_9 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.000000000000000000000000000000000000000000000000007649 190.0
TLS3_k127_7011218_0 regulation of circadian rhythm K08482 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006736 259.0
TLS3_k127_7011218_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000007965 246.0
TLS3_k127_7011218_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000001204 151.0
TLS3_k127_7011218_3 DNA polymerase III, delta subunit K02340 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.00001926 56.0
TLS3_k127_7018823_0 Urease alpha-subunit, N-terminal domain K01428 - 3.5.1.5 1.841e-272 848.0
TLS3_k127_7018823_1 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 425.0
TLS3_k127_7018823_2 Urease beta subunit K01430,K14048 - 3.5.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 300.0
TLS3_k127_7018823_3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.00000000000000000000000000000000000000003401 164.0
TLS3_k127_7020825_0 protein-containing complex disassembly K02837,K07133 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 7.763e-207 658.0
TLS3_k127_7020825_1 2-Nitropropane dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 609.0
TLS3_k127_7020825_2 Tetratricopeptide repeat - - - 0.00000001669 67.0
TLS3_k127_7024796_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 296.0
TLS3_k127_7024796_1 Protein of unknown function (DUF2089) - - - 0.0000000000000000000002758 101.0
TLS3_k127_7024796_2 Phage-associated protein - - - 0.000000000000000722 86.0
TLS3_k127_7024796_4 protein homooligomerization K21919 - - 0.00009022 54.0
TLS3_k127_7030995_0 dead DEAH box helicase - - - 8.921e-304 944.0
TLS3_k127_7030995_1 ABC transporter transmembrane region K11085 - - 2.336e-232 736.0
TLS3_k127_7030995_10 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005491 286.0
TLS3_k127_7030995_11 DTW K05812 - - 0.000000000000000000000000000000000000000000000000000000000000000002266 235.0
TLS3_k127_7030995_12 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000001904 242.0
TLS3_k127_7030995_13 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000005775 220.0
TLS3_k127_7030995_14 metal cluster binding K06940 - - 0.00000000000000000000000000000000000000000000000000000001832 205.0
TLS3_k127_7030995_15 addiction module antidote protein HigA K07110,K21686 - - 0.00000000000000000000000000000000000000000000000000001676 198.0
TLS3_k127_7030995_16 PFAM Activator of Hsp90 ATPase - - - 0.0000000000000000000000000000000000000000000000008666 179.0
TLS3_k127_7030995_17 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000001654 176.0
TLS3_k127_7030995_18 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000004729 169.0
TLS3_k127_7030995_19 YaeQ - - - 0.000000000000000000000000000000000000000000008877 179.0
TLS3_k127_7030995_2 Histidine kinase - - - 5.438e-206 671.0
TLS3_k127_7030995_20 - - - - 0.00000000000000000000000000000000000000000009801 161.0
TLS3_k127_7030995_21 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K16907 - - 0.00000000000000000000000000000000000000000241 170.0
TLS3_k127_7030995_22 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000000000000000000001916 160.0
TLS3_k127_7030995_23 - - - - 0.00000000000000000000000000000000003196 155.0
TLS3_k127_7030995_24 3'(2'),5'-bisphosphate nucleotidase activity K01082 - 3.1.3.7 0.00000000000000000000000000000000006639 144.0
TLS3_k127_7030995_25 Glycosyl hydrolases family 8 K15531 - 3.2.1.156 0.000000000000000000000000000000008038 137.0
TLS3_k127_7030995_26 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000007142 128.0
TLS3_k127_7030995_27 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000005064 128.0
TLS3_k127_7030995_28 Protein of unknown function (DUF2971) - - - 0.0000000000000000000000005842 115.0
TLS3_k127_7030995_29 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000006806 106.0
TLS3_k127_7030995_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 448.0
TLS3_k127_7030995_30 TonB-dependent receptor K02014 - - 0.0000000000209 65.0
TLS3_k127_7030995_31 - - - - 0.0000000001101 72.0
TLS3_k127_7030995_34 transmembrane transport K16906 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0015562,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.000000009374 67.0
TLS3_k127_7030995_35 - - - - 0.000001315 60.0
TLS3_k127_7030995_36 - - - - 0.000003541 59.0
TLS3_k127_7030995_38 NUDIX domain - - - 0.0003549 51.0
TLS3_k127_7030995_39 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0006898 53.0
TLS3_k127_7030995_4 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 400.0
TLS3_k127_7030995_5 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 348.0
TLS3_k127_7030995_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 349.0
TLS3_k127_7030995_7 Has an organic peroxide-dependent peroxidase activity K03781 - 1.11.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 334.0
TLS3_k127_7030995_8 PFAM Fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 314.0
TLS3_k127_7030995_9 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 297.0
TLS3_k127_7045608_0 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate K03473 - 1.1.1.290 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 298.0
TLS3_k127_7045608_1 serine acetyltransferase K00640 - 2.3.1.30 0.0000000000004354 81.0
TLS3_k127_7063311_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 602.0
TLS3_k127_7063311_1 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 591.0
TLS3_k127_7063311_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000005053 229.0
TLS3_k127_7063311_3 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000007517 177.0
TLS3_k127_7063311_4 cyclic nucleotide binding K01420,K10914 - - 0.00000000000000000000000000000000000000002185 166.0
TLS3_k127_7063311_5 phosphoprotein phosphatase activity - - - 0.00000000000000000000000006252 117.0
TLS3_k127_7063311_6 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594,K07052,K20087 - 1.16.3.1 0.0000007023 60.0
TLS3_k127_7063311_7 Putative zinc-finger - - - 0.000005314 59.0
TLS3_k127_7088752_0 TonB-dependent Receptor Plug Domain K02014 - - 1.329e-203 664.0
TLS3_k127_7088752_1 Alginate lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009483 508.0
TLS3_k127_7088752_10 acetyltransferase - - - 0.00000000000000000000000000000000000000000001472 171.0
TLS3_k127_7088752_11 mRNA binding K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000001203 163.0
TLS3_k127_7088752_12 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000008264 179.0
TLS3_k127_7088752_13 - - - - 0.0000000000000000000000000000000000000001122 160.0
TLS3_k127_7088752_14 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000005326 149.0
TLS3_k127_7088752_15 Cellulose Binding Domain Type IV - - - 0.00000000000000000000000000000000000003735 163.0
TLS3_k127_7088752_16 response regulator receiver K02481 - - 0.00000000000000003823 86.0
TLS3_k127_7088752_17 Trehalose utilisation K09992 - - 0.0000000000000007707 90.0
TLS3_k127_7088752_18 - - - - 0.000000001858 70.0
TLS3_k127_7088752_19 Histidine Phosphotransfer domain K20976 - - 0.000000628 56.0
TLS3_k127_7088752_2 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 478.0
TLS3_k127_7088752_3 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 344.0
TLS3_k127_7088752_4 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004666 279.0
TLS3_k127_7088752_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000007029 223.0
TLS3_k127_7088752_6 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000002729 212.0
TLS3_k127_7088752_7 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000004556 224.0
TLS3_k127_7088752_8 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000001429 194.0
TLS3_k127_7088752_9 - - - - 0.000000000000000000000000000000000000000000000001709 184.0
TLS3_k127_7103479_0 methionyl-tRNA aminoacylation K01874,K01890,K04566,K06878 GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0017102,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20,6.1.1.6 5e-227 724.0
TLS3_k127_7103479_1 precorrin-2 dehydrogenase activity K02302,K02303,K02304,K03795,K04719,K13542 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.79,1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.3,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000002457 281.0
TLS3_k127_7103479_2 Glycosyl transferase family 2 - - - 0.00000003128 55.0
TLS3_k127_7118521_0 Proton-conducting membrane transporter K12137 - - 1.762e-297 924.0
TLS3_k127_7118521_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 1.327e-211 667.0
TLS3_k127_7118521_10 Pyruvate kinase, alpha/beta domain K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000006546 228.0
TLS3_k127_7118521_11 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000006869 162.0
TLS3_k127_7118521_12 Bacterial transcription activator, effector binding domain - - - 0.0000000000000002878 83.0
TLS3_k127_7118521_13 HD domain - - - 0.0000000000001059 83.0
TLS3_k127_7118521_2 phosphoglucomutase activity K01835 GO:0000271,GO:0003674,GO:0003824,GO:0004614,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005996,GO:0006006,GO:0006012,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0016868,GO:0019318,GO:0019320,GO:0019388,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0055114,GO:0071704,GO:1901575,GO:1901576 5.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 480.0
TLS3_k127_7118521_3 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 411.0
TLS3_k127_7118521_4 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 381.0
TLS3_k127_7118521_5 Proton-conducting membrane transporter K12141 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033554,GO:0044425,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 353.0
TLS3_k127_7118521_6 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006409 301.0
TLS3_k127_7118521_7 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001343 270.0
TLS3_k127_7118521_8 Protein of unknown function (DUF3365) K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003639 257.0
TLS3_k127_7118521_9 - K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000961 233.0
TLS3_k127_7122438_0 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 317.0
TLS3_k127_7122438_1 AcrB/AcrD/AcrF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002389 258.0
TLS3_k127_7139358_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381 - 1.2.4.1,1.2.4.4 0.0 1097.0
TLS3_k127_7139358_1 Transglycosylase - - - 1.864e-302 965.0
TLS3_k127_7139358_10 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.0000004685 54.0
TLS3_k127_7139358_11 Belongs to the ompA family - - - 0.000004667 59.0
TLS3_k127_7139358_12 PFAM Forkhead-associated protein - - - 0.00000736 59.0
TLS3_k127_7139358_13 Protein of unknown function (DUF3592) - - - 0.00004862 52.0
TLS3_k127_7139358_2 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 410.0
TLS3_k127_7139358_3 Lytic transglycosylase catalytic K08307 - - 0.0000000000000000000000000000001537 141.0
TLS3_k127_7139358_4 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000000004949 127.0
TLS3_k127_7139358_5 - - - - 0.000000000000000000000000000002352 123.0
TLS3_k127_7139358_6 Peptidase family M48 - - - 0.00000000000000000000000000008652 126.0
TLS3_k127_7139358_7 Helix-turn-helix domain - - - 0.000000000000008905 76.0
TLS3_k127_7139358_8 Domain of unknown function (DUF4142) K08995 - - 0.000000000168 70.0
TLS3_k127_7139358_9 Outer membrane protein beta-barrel domain - - - 0.000000001048 68.0
TLS3_k127_7142641_0 Belongs to the glycosyl hydrolase family 6 K05988 - 3.2.1.11 4.267e-278 918.0
TLS3_k127_7142641_1 Phage tail sheath C-terminal domain K06907 - - 1.298e-237 758.0
TLS3_k127_7142641_10 - - - - 0.0000000000000000000000000000000000000003573 161.0
TLS3_k127_7142641_11 LysM domain - - - 0.00000000000004131 74.0
TLS3_k127_7142641_2 PFAM ATPase family associated with various cellular activities (AAA) - - - 1.601e-206 676.0
TLS3_k127_7142641_3 protein refolding K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 6.251e-206 653.0
TLS3_k127_7142641_4 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 344.0
TLS3_k127_7142641_5 Protein of unknown function (DUF4255) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009089 307.0
TLS3_k127_7142641_6 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 294.0
TLS3_k127_7142641_7 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001608 268.0
TLS3_k127_7142641_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009736 267.0
TLS3_k127_7142641_9 Ribose-phosphate pyrophosphokinase K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000055 240.0
TLS3_k127_7143058_0 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 4.176e-302 947.0
TLS3_k127_7143058_1 membrane organization K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 528.0
TLS3_k127_7143058_10 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity K19405 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0000000000000000007258 99.0
TLS3_k127_7143058_11 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity K02535,K13599,K16363 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108,4.2.1.59 0.000000000000000002759 97.0
TLS3_k127_7143058_13 PFAM UvrB UvrC protein K19411 - - 0.00001934 53.0
TLS3_k127_7143058_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000001045 221.0
TLS3_k127_7143058_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000002954 197.0
TLS3_k127_7143058_4 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000981 183.0
TLS3_k127_7143058_5 unfolded protein binding K06142 - - 0.0000000000000000000000000000000000000000000000009174 179.0
TLS3_k127_7143058_6 addiction module antidote protein HigA K07110,K21686 - - 0.00000000000000000000000000000000000001294 156.0
TLS3_k127_7143058_7 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000009843 154.0
TLS3_k127_7143058_8 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000001115 142.0
TLS3_k127_7143058_9 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000001266 109.0
TLS3_k127_7144998_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688,K21298 - 2.4.1.20,2.4.1.333 0.0 1028.0
TLS3_k127_7144998_1 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 567.0
TLS3_k127_7144998_2 PFAM Cytochrome c, class I K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001463 294.0
TLS3_k127_7144998_3 dextransucrase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000273 256.0
TLS3_k127_7144998_4 PKD domain - - - 0.00000000000003551 87.0
TLS3_k127_7144998_5 Dual-action HEIGH metallo-peptidase - - - 0.000000000005024 79.0
TLS3_k127_7144998_6 Domain of unknown function DUF11 - - - 0.00000000000667 80.0
TLS3_k127_7144998_7 PFAM Cytochrome c, class I K08738 - - 0.0000000003118 70.0
TLS3_k127_7144998_8 6-phosphogluconolactonase activity - - - 0.000000001648 72.0
TLS3_k127_7144998_9 InterPro IPR010496 - - - 0.0000000265 61.0
TLS3_k127_7186642_0 4-amino-4-deoxy-L-arabinose transferase activity K16928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 558.0
TLS3_k127_7186642_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 460.0
TLS3_k127_7186642_10 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000003858 181.0
TLS3_k127_7186642_11 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571 - 4.1.1.3 0.000000000000000000000000000009605 124.0
TLS3_k127_7186642_12 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000001249 119.0
TLS3_k127_7186642_13 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000143 111.0
TLS3_k127_7186642_14 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.000000000000000000000004493 104.0
TLS3_k127_7186642_15 lysyltransferase activity K07027 - - 0.000000000000000000000052 115.0
TLS3_k127_7186642_16 Tetratricopeptide repeat - - - 0.000000000005773 80.0
TLS3_k127_7186642_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 388.0
TLS3_k127_7186642_3 malonyl-CoA biosynthetic process K01962,K01963 GO:0001676,GO:0003674,GO:0003824,GO:0003989,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0042759,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494,GO:1990234 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 365.0
TLS3_k127_7186642_4 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008669 337.0
TLS3_k127_7186642_5 transferase activity, transferring glycosyl groups K00721,K03820 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 295.0
TLS3_k127_7186642_6 undecaprenyl-phosphate glucose phosphotransferase activity K03606,K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 305.0
TLS3_k127_7186642_7 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000153 268.0
TLS3_k127_7186642_8 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000002518 209.0
TLS3_k127_7186642_9 dTDP-4-dehydrorhamnose reductase activity K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000003172 189.0
TLS3_k127_7204126_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 382.0
TLS3_k127_7204126_1 SMART Elongator protein 3 MiaB NifB K07139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002556 282.0
TLS3_k127_7204126_11 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000006761 92.0
TLS3_k127_7204126_12 - - - - 0.00000000000000001896 92.0
TLS3_k127_7204126_13 ThiS family K03636 - - 0.0000000000001341 75.0
TLS3_k127_7204126_14 Conserved nitrate reductase-associated protein (Nitr_red_assoc) - - - 0.000000000002896 75.0
TLS3_k127_7204126_15 COG2010 Cytochrome c, mono- and diheme variants K07243 - - 0.0000000009168 66.0
TLS3_k127_7204126_16 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K03778 - 1.1.1.28 0.000007389 48.0
TLS3_k127_7204126_17 Cytochrome oxidase maturation protein - - - 0.00002597 51.0
TLS3_k127_7204126_18 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K18916 - 1.20.1.1 0.0000402 49.0
TLS3_k127_7204126_2 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002122 282.0
TLS3_k127_7204126_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000001117 264.0
TLS3_k127_7204126_4 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000366 252.0
TLS3_k127_7204126_5 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.0000000000000000000000000000000000000000000000000002646 187.0
TLS3_k127_7204126_6 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000004794 204.0
TLS3_k127_7204126_7 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000002244 176.0
TLS3_k127_7204126_8 molybdopterin synthase activity K03635,K21147 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.7.7.80,2.8.1.11,2.8.1.12 0.000000000000000000000000000000000000003847 151.0
TLS3_k127_7204126_9 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.0000000000000000000000002607 108.0
TLS3_k127_7208902_0 Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 484.0
TLS3_k127_7208902_1 Domain of Unknown Function (DUF1080) - - - 0.0000000007716 68.0
TLS3_k127_7208902_2 COG0642 Signal transduction histidine kinase K20971 - - 0.00000004992 58.0
TLS3_k127_7214563_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 3.845e-225 713.0
TLS3_k127_7214563_1 Anticodon binding domain K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 477.0
TLS3_k127_7214563_2 Adenine specific DNA methylase Mod K07316 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 306.0
TLS3_k127_7214563_3 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000007059 232.0
TLS3_k127_7214563_4 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 - 5.4.2.8 0.0000000000000256 74.0
TLS3_k127_7215188_0 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000452 245.0
TLS3_k127_7215188_1 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000000000000000002811 201.0
TLS3_k127_7215188_10 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07665 - - 0.0001065 51.0
TLS3_k127_7215188_2 PFAM Metal-dependent phosphohydrolase, HD - - - 0.000000000000000000000000000000000000000002947 170.0
TLS3_k127_7215188_3 Flagellar Assembly Protein A K09749 - - 0.00000000000000000000000000000000000005135 164.0
TLS3_k127_7215188_4 protein-glutamate methylesterase activity K03412,K03413 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000007225 143.0
TLS3_k127_7215188_5 Histidine Phosphotransfer domain K03407 - 2.7.13.3 0.000000000000000000000000000002271 137.0
TLS3_k127_7215188_6 Nudix hydrolase - - - 0.00000000000000000000000000001203 123.0
TLS3_k127_7215188_7 domain, Protein K20276 - - 0.0000000000000000000000000001011 136.0
TLS3_k127_7215188_9 Transcriptional regulator - - - 0.00001984 53.0
TLS3_k127_7218597_0 bacteriocin transport K03561,K03562 - - 0.000000000000000000000000000000000000000000001692 173.0
TLS3_k127_7218597_1 biopolymer transport protein K03559,K03560 - - 0.00000000000000000000000000003221 122.0
TLS3_k127_7218597_2 Involved in the tonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - 0.00000000000000000000000003367 117.0
TLS3_k127_7218597_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000009207 98.0
TLS3_k127_7218597_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000008642 57.0
TLS3_k127_7236471_0 Belongs to the DEAD box helicase family K03732,K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 398.0
TLS3_k127_7236471_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 347.0
TLS3_k127_7236471_10 COG0848 Biopolymer transport protein - - - 0.00000009073 61.0
TLS3_k127_7236471_11 GGDEF domain K21019 - 2.7.7.65 0.0000001064 65.0
TLS3_k127_7236471_12 Biopolymer transport protein ExbD/TolR - - - 0.0000002099 59.0
TLS3_k127_7236471_13 CobQ CobB MinD ParA nucleotide binding domain K16554,K16692 - - 0.00002357 57.0
TLS3_k127_7236471_2 response regulator receiver K07714,K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 338.0
TLS3_k127_7236471_3 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008026 296.0
TLS3_k127_7236471_4 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000008565 198.0
TLS3_k127_7236471_5 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000009213 141.0
TLS3_k127_7236471_6 Periplasmic protein involved in polysaccharide export - - - 0.0000000000000003412 90.0
TLS3_k127_7236471_8 response regulator - - - 0.000000002465 63.0
TLS3_k127_7236471_9 Forkhead associated domain - - - 0.000000005768 67.0
TLS3_k127_7256658_0 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 332.0
TLS3_k127_7256658_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 301.0
TLS3_k127_7256658_2 Membrane protein TerC, possibly involved in tellurium resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002559 277.0
TLS3_k127_7256658_3 helicase activity K06889 - - 0.00000000000000000000000000001445 129.0
TLS3_k127_7256658_4 FlgD Ig-like domain - - - 0.0000002443 58.0
TLS3_k127_7267846_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 404.0
TLS3_k127_7267846_1 - K00241 - - 0.0000000000000000000000000000000000000001158 168.0
TLS3_k127_7267846_2 addiction module antidote protein HigA K07110,K21686 - - 0.00000000000000000000000000000000002338 147.0
TLS3_k127_7267846_3 Histidine kinase - - - 0.000000000000000001503 93.0
TLS3_k127_7267846_4 long-chain fatty acid transport protein K06076 - - 0.000000000000001074 90.0
TLS3_k127_7267846_5 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.000000002985 57.0
TLS3_k127_7279410_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008904 434.0
TLS3_k127_7279410_1 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008405 275.0
TLS3_k127_7279410_10 Parallel beta-helix repeats - - - 0.00000473 59.0
TLS3_k127_7279410_11 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000179 57.0
TLS3_k127_7279410_2 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000004452 227.0
TLS3_k127_7279410_3 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000006958 222.0
TLS3_k127_7279410_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000001305 209.0
TLS3_k127_7279410_5 peptidoglycan turnover K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.000000000000000000000000000000000000000000000000000798 196.0
TLS3_k127_7279410_6 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000002141 149.0
TLS3_k127_7279410_7 Trm112p-like protein - - - 0.000000000000000000000000000000004606 138.0
TLS3_k127_7279410_8 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000006946 143.0
TLS3_k127_7279410_9 TIGRFAM methyltransferase FkbM - - - 0.00000000000000000000000009541 118.0
TLS3_k127_7286061_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity K00765 GO:0000105,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003879,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016020,GO:0016053,GO:0016208,GO:0016740,GO:0016757,GO:0016763,GO:0017076,GO:0018130,GO:0019438,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0052803,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 319.0
TLS3_k127_7286061_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002691 289.0
TLS3_k127_7286061_2 phosphoribosyl-ATP diphosphatase activity K01523,K01814,K11755 GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31,5.3.1.16 0.00000000000000000000000000000000004244 137.0
TLS3_k127_7301848_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 514.0
TLS3_k127_7301848_1 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 501.0
TLS3_k127_7301848_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 359.0
TLS3_k127_7301848_3 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000009884 238.0
TLS3_k127_7301848_4 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000001231 230.0
TLS3_k127_7301848_5 dna-directed rna polymerase K08309,K10908,K21313 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000002891 236.0
TLS3_k127_7301848_6 nuclear chromosome segregation - - - 0.000000000000000000001154 111.0
TLS3_k127_7301848_7 phosphocarrier protein HPr K11189 - - 0.0000000000000000003167 92.0
TLS3_k127_7312547_0 GMP synthase (glutamine-hydrolyzing) activity K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 619.0
TLS3_k127_7312547_1 ATP-dependent DNA helicase activity K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 526.0
TLS3_k127_7312547_2 GAF domain K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008831 417.0
TLS3_k127_7312547_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000697 405.0
TLS3_k127_7312547_4 6-phosphogluconolactonase activity - - - 0.00008505 48.0
TLS3_k127_7337764_0 quinolinate synthetase A activity K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0030312,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 447.0
TLS3_k127_7337764_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001813 277.0
TLS3_k127_7337764_2 metallocarboxypeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003781 251.0
TLS3_k127_7337764_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000002934 216.0
TLS3_k127_7337764_4 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00847,K00852,K18478 - 2.7.1.15,2.7.1.184,2.7.1.4 0.000000000000000000000000000000000000000000000000000002715 207.0
TLS3_k127_7337764_5 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000000000000000000000000008623 194.0
TLS3_k127_7337764_6 Protein of unknown function (DUF420) K08976 - - 0.0000000000000000000000000000000000000000000004922 171.0
TLS3_k127_7337764_7 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000008162 132.0
TLS3_k127_7337764_8 Uncharacterized protein conserved in bacteria (DUF2334) K06986 - - 0.0000000000000001575 89.0
TLS3_k127_7353138_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 471.0
TLS3_k127_7353138_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 433.0
TLS3_k127_7353138_3 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009602 276.0
TLS3_k127_7353138_4 PALM domain HD hydrolase domain and K09749 - - 0.000000000000000000000000000000000000000000006488 182.0
TLS3_k127_7353138_5 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.00000000000000000000000000000000000002574 162.0
TLS3_k127_7353138_6 HD domain - - - 0.00000000000000000000000000000000001285 150.0
TLS3_k127_7353138_8 dUTPase - - - 0.0000000000000001415 86.0
TLS3_k127_7363731_0 TonB dependent receptor K02014 - - 0.0 1097.0
TLS3_k127_7363731_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000001836 254.0
TLS3_k127_7363731_2 dUTP biosynthetic process K01494 - 3.5.4.13 0.00000000000000000000000000001518 123.0
TLS3_k127_7363731_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000002549 107.0
TLS3_k127_7363731_4 Domain of unknown function (DUF2341) - - - 0.000000000000000000001688 112.0
TLS3_k127_7363731_5 Alpha galactosidase A - - - 0.0000000000000000001809 106.0
TLS3_k127_7363731_6 Domain of unknown function (DUF2341) K03561 - - 0.000000004392 71.0
TLS3_k127_7364864_0 DNA-directed DNA polymerase activity K02342,K03722,K03763 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 409.0
TLS3_k127_7364864_1 Phenazine biosynthesis-like protein K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 297.0
TLS3_k127_7364864_2 signal peptide processing K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000004742 186.0
TLS3_k127_7364864_3 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000003959 174.0
TLS3_k127_7364864_4 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000007563 146.0
TLS3_k127_7364864_5 - - - - 0.0000000000000000000000000000000001249 144.0
TLS3_k127_7364864_6 Bacterial Ig-like domain - - - 0.0000000000000002175 94.0
TLS3_k127_7364864_7 Lipopolysaccharide-assembly - - - 0.000000001034 70.0
TLS3_k127_7400739_0 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 421.0
TLS3_k127_7400739_1 Fic/DOC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 389.0
TLS3_k127_7400739_2 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004218 264.0
TLS3_k127_7400739_3 rho-dependent transcription termination K19000 - - 0.000009213 52.0
TLS3_k127_7403975_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1134.0
TLS3_k127_7403975_1 PA14 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005186 283.0
TLS3_k127_7403975_2 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000006584 171.0
TLS3_k127_740638_0 Peptidase C14, caspase catalytic - - - 0.000000000000000000000000000000000000000001873 172.0
TLS3_k127_740638_1 Integrin alpha (beta-propellor repeats). - - - 0.0000000000000000000084 108.0
TLS3_k127_740638_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000264 94.0
TLS3_k127_740638_3 Beta-lactamase - - - 0.0000008169 63.0
TLS3_k127_740638_4 Bacterial SH3 domain homologues K01447 - 3.5.1.28 0.00000565 57.0
TLS3_k127_7421727_0 Bacterial type II and III secretion system protein K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 387.0
TLS3_k127_7421727_1 Type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002333 279.0
TLS3_k127_7421727_2 carbon utilization K02664 - - 0.0002346 53.0
TLS3_k127_7438129_0 domain protein K01179,K01342,K01406,K07004,K12287,K14194,K15125,K20276 - 3.2.1.4,3.4.21.62,3.4.24.40 0.000000000000000000005474 109.0
TLS3_k127_7457131_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 476.0
TLS3_k127_7457131_1 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000007309 145.0
TLS3_k127_7457131_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000002773 104.0
TLS3_k127_7457131_4 TRANSCRIPTIONal - - - 0.0000000000001038 77.0
TLS3_k127_7481503_0 HsdM N-terminal domain K03427 - 2.1.1.72 7.706e-319 988.0
TLS3_k127_7481503_1 Ammonium Transporter Family - - - 0.0000000000000000000000000005844 116.0
TLS3_k127_7481503_2 Belongs to the 'phage' integrase family - - - 0.000003752 49.0
TLS3_k127_7508553_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 363.0
TLS3_k127_7508553_1 histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 323.0
TLS3_k127_7508553_11 Domain of unknown function (DUF4349) - - - 0.00000000005673 72.0
TLS3_k127_7508553_12 Peptidase family C25 - - - 0.00000000008477 75.0
TLS3_k127_7508553_13 Zinc metalloprotease (Elastase) - - - 0.00000009483 63.0
TLS3_k127_7508553_15 Domain of unknown function (DUF4349) - - - 0.00007938 55.0
TLS3_k127_7508553_2 rRNA processing K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000007735 269.0
TLS3_k127_7508553_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000002147 239.0
TLS3_k127_7508553_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000004432 228.0
TLS3_k127_7508553_5 GcpE protein K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000006874 207.0
TLS3_k127_7508553_6 - - - - 0.0000000000000000000000000000000000000000000000003001 186.0
TLS3_k127_7508553_7 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.00000000000000000000000000000001427 130.0
TLS3_k127_7508553_8 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.1.1.200 0.000000000000000000000007289 112.0
TLS3_k127_7508553_9 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000001186 95.0
TLS3_k127_7511908_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07714,K19641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 376.0
TLS3_k127_7511908_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000378 175.0
TLS3_k127_7511908_2 PIN domain - - - 0.000003657 55.0
TLS3_k127_7525050_0 DNA topoisomerase II activity K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 1.103e-261 821.0
TLS3_k127_7525050_1 Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP) K00209 - 1.3.1.44,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009219 304.0
TLS3_k127_7525050_10 Domain of unknown function (DUF2341) - - - 0.0000000000000000003339 103.0
TLS3_k127_7525050_11 Protein of unknown function (DUF3570) - - - 0.000000000000001205 90.0
TLS3_k127_7525050_12 Bacterial Ig-like domain 2 - - - 0.0000000001613 76.0
TLS3_k127_7525050_13 Protein of unknown function (DUF721) - - - 0.0000001424 58.0
TLS3_k127_7525050_14 domain, Protein - - - 0.000003416 57.0
TLS3_k127_7525050_15 Domain of unknown function (DUF4266) - - - 0.0006879 45.0
TLS3_k127_7525050_2 DNA-directed DNA polymerase activity K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 294.0
TLS3_k127_7525050_3 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000002324 239.0
TLS3_k127_7525050_4 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000004947 220.0
TLS3_k127_7525050_5 addiction module antidote protein HigA K07110,K21686 - - 0.0000000000000000000000000000000000000000000009466 177.0
TLS3_k127_7525050_6 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000002448 180.0
TLS3_k127_7525050_7 cell wall organization - - - 0.000000000000000000000000000000000143 155.0
TLS3_k127_7525050_8 6-phosphogluconolactonase activity - - - 0.0000000000000000000000000000267 138.0
TLS3_k127_7525050_9 Thioredoxin - - - 0.000000000000000000000566 104.0
TLS3_k127_7539273_0 GTPase activity K06207 GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 539.0
TLS3_k127_7539273_1 Dioxygenase K03381 - 1.13.11.1 0.00000000000000000000001463 112.0
TLS3_k127_7539273_2 PFAM BNR Asp-box repeat - - - 0.0001934 53.0
TLS3_k127_7545224_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 6.15e-202 644.0
TLS3_k127_7545224_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000001218 159.0
TLS3_k127_7550274_0 ADP-glyceromanno-heptose 6-epimerase activity K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 405.0
TLS3_k127_7550274_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004602 270.0
TLS3_k127_7550274_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000271 106.0
TLS3_k127_7550274_3 Belongs to the Fur family K02076,K03711 - - 0.0000000000001473 77.0
TLS3_k127_7550274_4 ZIP Zinc transporter K16267 - - 0.000000001763 68.0
TLS3_k127_7550274_5 Belongs to the peptidase S8 family - - - 0.00000272 62.0
TLS3_k127_7550274_6 Small MutS-related domain - - - 0.00001909 53.0
TLS3_k127_7568082_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001405 256.0
TLS3_k127_7568082_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000002726 173.0
TLS3_k127_7568082_2 - - - - 0.00000000000000001089 95.0
TLS3_k127_7568082_3 Peptidase family M23 - - - 0.000000000006832 77.0
TLS3_k127_7574810_0 Outer membrane receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 405.0
TLS3_k127_7574810_1 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000005378 96.0
TLS3_k127_7574810_2 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000001051 79.0
TLS3_k127_7574810_3 peptidyl-tyrosine sulfation - - - 0.00000000000006727 83.0
TLS3_k127_7574810_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00004276 54.0
TLS3_k127_760395_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 395.0
TLS3_k127_760395_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 303.0
TLS3_k127_760395_10 - - - - 0.0000000000000000000000000000000000008014 148.0
TLS3_k127_760395_11 Tetratricopeptide repeat - - - 0.00000000000000000000000005503 126.0
TLS3_k127_760395_12 Tetratricopeptide repeat - - - 0.00000000000000000001371 109.0
TLS3_k127_760395_13 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000001915 79.0
TLS3_k127_760395_14 - - - - 0.00000003427 54.0
TLS3_k127_760395_16 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0002384 55.0
TLS3_k127_760395_17 Lamin Tail Domain - - - 0.0003183 53.0
TLS3_k127_760395_18 Cell wall arabinan synthesis protein K11386,K11387 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0052636,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0006641 50.0
TLS3_k127_760395_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 301.0
TLS3_k127_760395_3 protein histidine kinase activity K02484,K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001675 273.0
TLS3_k127_760395_4 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000001209 237.0
TLS3_k127_760395_5 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000004072 220.0
TLS3_k127_760395_6 phosphatidylcholine synthase activity K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000008541 205.0
TLS3_k127_760395_7 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000001387 197.0
TLS3_k127_760395_8 Yip1 domain - - - 0.000000000000000000000000000000000000000000000000000537 190.0
TLS3_k127_760395_9 - - - - 0.00000000000000000000000000000000000000004582 162.0
TLS3_k127_7622349_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 307.0
TLS3_k127_7622349_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.7.1.148 0.000000000000000000000000000000001394 136.0
TLS3_k127_7629996_0 cell redox homeostasis - - - 0.00000000000000000000000000000321 128.0
TLS3_k127_7629996_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000001124 83.0
TLS3_k127_7644363_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 430.0
TLS3_k127_7644363_1 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006607 286.0
TLS3_k127_7644363_2 PFAM Conserved nitrate reductase-associated protein (Nitr_red_assoc) - - - 0.00000000000000000000000000000000000918 154.0
TLS3_k127_7644363_3 cellulose binding - - - 0.0000000008904 71.0
TLS3_k127_7672130_0 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000006812 165.0
TLS3_k127_7672130_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000001356 51.0
TLS3_k127_7672130_3 antisigma factor binding K04749,K06378 - - 0.000007733 55.0
TLS3_k127_7682289_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 542.0
TLS3_k127_7682289_1 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000005626 167.0
TLS3_k127_7682289_2 Hydrolase of the alpha beta-hydrolase K07020 - - 0.00000000000000000000000000000000000002844 151.0
TLS3_k127_7682289_3 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000001287 117.0
TLS3_k127_7682289_4 CarboxypepD_reg-like domain - - - 0.00000001394 66.0
TLS3_k127_7702629_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.138e-210 677.0
TLS3_k127_7702629_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.541e-203 657.0
TLS3_k127_7702629_10 repeat protein - - - 0.0001281 50.0
TLS3_k127_7702629_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001338 232.0
TLS3_k127_7702629_3 Acyl-transferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000005461 189.0
TLS3_k127_7702629_4 Response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000000000000006099 139.0
TLS3_k127_7702629_5 repeat protein - - - 0.00000000000000000000000000000001849 148.0
TLS3_k127_7702629_6 exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000379 112.0
TLS3_k127_7702629_7 Phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000009268 97.0
TLS3_k127_7702629_8 His Kinase A (phosphoacceptor) domain - - - 0.0000001011 64.0
TLS3_k127_7702629_9 Glucose / Sorbosone dehydrogenase - - - 0.00002491 59.0
TLS3_k127_7702714_0 Helicase associated domain - - - 0.000000000000000000000000000000000004078 155.0
TLS3_k127_7702714_1 COGs COG5421 Transposase - - - 0.0000000000000000000000000000000002413 137.0
TLS3_k127_7702714_2 CotH kinase protein - - - 0.000000000000000000000000000001722 140.0
TLS3_k127_7702714_3 Hep Hag repeat protein - - - 0.00000000000000003116 97.0
TLS3_k127_7702714_4 - - - - 0.000001784 58.0
TLS3_k127_7745783_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 443.0
TLS3_k127_7745783_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 454.0
TLS3_k127_7745783_10 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K00627 - 1.2.4.1,2.3.1.12 0.0000000000000000000000005995 109.0
TLS3_k127_7745783_11 ATPase activity K02065 - - 0.0000000000000000000347 91.0
TLS3_k127_7745783_12 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000429 98.0
TLS3_k127_7745783_13 Tetratricopeptide repeat - - - 0.00000000001232 78.0
TLS3_k127_7745783_16 Recombinase zinc beta ribbon domain - - - 0.0001209 45.0
TLS3_k127_7745783_2 (ABC) transporter K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 443.0
TLS3_k127_7745783_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 376.0
TLS3_k127_7745783_4 PHP domain protein K03763 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 368.0
TLS3_k127_7745783_5 ABC transporter transmembrane region K06147,K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 331.0
TLS3_k127_7745783_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000001151 267.0
TLS3_k127_7745783_7 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000009751 230.0
TLS3_k127_7745783_8 Flavin reductase like domain - - - 0.0000000000000000000000000000000002898 138.0
TLS3_k127_7745783_9 ERF superfamily - - - 0.00000000000000000000000001307 121.0
TLS3_k127_7747247_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1180.0
TLS3_k127_7747247_1 PFAM glycosyl transferase family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 1.83e-249 791.0
TLS3_k127_7747247_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000002476 106.0
TLS3_k127_7747247_11 PFAM Outer membrane efflux protein K15725 - - 0.000000000000000009149 96.0
TLS3_k127_7747247_12 helix_turn_helix multiple antibiotic resistance protein - - - 0.000004995 55.0
TLS3_k127_7747247_13 response regulator K02485 - - 0.00000973 53.0
TLS3_k127_7747247_2 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 422.0
TLS3_k127_7747247_3 CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 414.0
TLS3_k127_7747247_4 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 358.0
TLS3_k127_7747247_5 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 335.0
TLS3_k127_7747247_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007146 261.0
TLS3_k127_7747247_7 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000001371 208.0
TLS3_k127_7747247_8 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000004443 202.0
TLS3_k127_7747247_9 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000005755 163.0
TLS3_k127_7749361_0 Cupin superfamily (DUF985) K09705 - - 0.000000000000000000000000000000000000002692 151.0
TLS3_k127_7749361_2 Pentapeptide repeats (9 copies) - - - 0.0000000001248 69.0
TLS3_k127_7749361_3 DNA circulation - - - 0.00007541 53.0
TLS3_k127_7749361_4 - - - - 0.0001981 53.0
TLS3_k127_7750387_0 prohibitin homologues K07192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007865 546.0
TLS3_k127_7750387_1 symporter activity K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 464.0
TLS3_k127_7750387_10 Exopolysaccharide synthesis, ExoD - - - 0.000000000000000000000000000000000002546 149.0
TLS3_k127_7750387_11 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000001417 146.0
TLS3_k127_7750387_12 PA14 domain - - - 0.0000000000000000000000000009124 123.0
TLS3_k127_7750387_13 serine protease - - - 0.000000000000000000000000002128 119.0
TLS3_k127_7750387_14 Domain of unknown function (DUF3817) - - - 0.000000000000000000001888 97.0
TLS3_k127_7750387_15 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000002755 76.0
TLS3_k127_7750387_16 - - - - 0.000000000008642 75.0
TLS3_k127_7750387_2 PFAM sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 455.0
TLS3_k127_7750387_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 394.0
TLS3_k127_7750387_4 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 299.0
TLS3_k127_7750387_5 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 304.0
TLS3_k127_7750387_6 Bacterial regulatory helix-turn-helix protein, lysR family K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003009 281.0
TLS3_k127_7750387_7 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002273 250.0
TLS3_k127_7750387_8 Belongs to the GPI family K01810 GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 0.00000000000000000000000000000000000000000000000000000001247 213.0
TLS3_k127_7750387_9 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000001303 192.0
TLS3_k127_7771650_0 COG0475 Kef-type K transport systems, membrane components K03455 - - 0.000000000000000000000000000000003233 132.0
TLS3_k127_7771650_1 Hemerythrin HHE cation binding domain - - - 0.000000002064 64.0
TLS3_k127_7771650_2 Protein of unknown function (DUF433) - - - 0.000000004458 61.0
TLS3_k127_7772409_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 528.0
TLS3_k127_7772409_1 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 391.0
TLS3_k127_7772409_2 Probable molybdopterin binding domain K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000004274 253.0
TLS3_k127_7772409_3 HhH-GPD family K03575 - - 0.000000000000000000000000000000000000000000000000000000000006021 226.0
TLS3_k127_7772409_5 Ribosomal L27 protein K02899 - - 0.00000000000000000000000000000000000005298 143.0
TLS3_k127_7772409_6 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 0.00000000000000001986 98.0
TLS3_k127_7772409_7 extracellular matrix structural constituent K13714 - 3.2.1.96,3.5.1.28 0.00000000234 72.0
TLS3_k127_7783637_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009888 540.0
TLS3_k127_7783637_1 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000002756 160.0
TLS3_k127_7783637_2 Sucrose-6F-phosphate phosphohydrolase - - - 0.00000000000000000000000000000014 135.0
TLS3_k127_7824610_0 undecaprenyl-phosphate glucose phosphotransferase activity K05946,K21303 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016780,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046402,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.187,2.7.8.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 322.0
TLS3_k127_7824610_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000006068 129.0
TLS3_k127_7824610_2 - - - - 0.00001791 49.0
TLS3_k127_7828147_0 alpha-2-macroglobulin domain protein K06894 - - 3.479e-262 875.0
TLS3_k127_7828147_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 532.0
TLS3_k127_7828147_10 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000003565 249.0
TLS3_k127_7828147_11 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000001567 194.0
TLS3_k127_7828147_12 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000004586 190.0
TLS3_k127_7828147_13 GMP synthase (glutamine-hydrolyzing) activity K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000002516 106.0
TLS3_k127_7828147_14 peptidyl-tyrosine sulfation - - - 0.0000000000000005709 94.0
TLS3_k127_7828147_15 Tetratricopeptide TPR_2 repeat protein - - - 0.0000003853 65.0
TLS3_k127_7828147_16 Aerotolerance regulator N-terminal - - - 0.000002001 61.0
TLS3_k127_7828147_17 Tetratricopeptide repeat - - - 0.00007116 57.0
TLS3_k127_7828147_2 shikimate kinase activity K00891,K01524,K01735,K13829,K16020,K19969,K21342 GO:0000166,GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.71,3.6.1.11,3.6.1.40,4.2.3.152,4.2.3.154,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 484.0
TLS3_k127_7828147_3 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 456.0
TLS3_k127_7828147_4 UTP--glucose-1-phosphate uridylyltransferase K11442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 462.0
TLS3_k127_7828147_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 370.0
TLS3_k127_7828147_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 329.0
TLS3_k127_7828147_7 GDP-mannose 4,6-dehydratase activity K01711,K15856 - 1.1.1.281,4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 312.0
TLS3_k127_7828147_8 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 297.0
TLS3_k127_7828147_9 Peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003316 265.0
TLS3_k127_7833182_0 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 323.0
TLS3_k127_7833182_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000675 260.0
TLS3_k127_7833182_2 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000000000000000000000001083 156.0
TLS3_k127_7833182_3 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000004833 97.0
TLS3_k127_7841733_2 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 442.0
TLS3_k127_7841733_6 HAF family - - - 0.00002079 57.0
TLS3_k127_7841733_7 SNF2 family N-terminal domain - - - 0.0008741 42.0
TLS3_k127_7842380_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 482.0
TLS3_k127_7842380_1 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 342.0
TLS3_k127_7842380_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003556 279.0
TLS3_k127_7842380_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000001498 150.0
TLS3_k127_7866747_0 COG0286 Type I restriction-modification system K03427 - 2.1.1.72 3.993e-265 823.0
TLS3_k127_7866747_1 Protein of unknown function (DUF1016) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 415.0
TLS3_k127_7866747_2 BRO family, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 392.0
TLS3_k127_7889036_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 416.0
TLS3_k127_7889036_1 carbohydrate transport K17234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 398.0
TLS3_k127_7889036_10 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000000003054 205.0
TLS3_k127_7889036_11 glycerophosphodiester transmembrane transport K02026 - - 0.000000000000000000000000000000000000000000000000000002474 201.0
TLS3_k127_7889036_12 transmembrane transport K02025,K15771,K17235 - - 0.000000000000000000000000000000000000000000000000000006852 201.0
TLS3_k127_7889036_13 type VI secretion protein, VC_A0111 family K11895 - - 0.000000000000000000000000000005517 134.0
TLS3_k127_7889036_14 Domain of unknown function (DUF2341) - - - 0.0000000000000000000000001435 123.0
TLS3_k127_7889036_15 Type VI secretion system K11905 - - 0.00000000000000000000007541 105.0
TLS3_k127_7889036_16 Histidine kinase - - - 0.0000000000000000000004614 101.0
TLS3_k127_7889036_17 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000004098 96.0
TLS3_k127_7889036_18 acetyltransferase K03823 - 2.3.1.183 0.00000000000000000111 87.0
TLS3_k127_7889036_19 PFAM Cold-shock protein, DNA-binding - - - 0.00000000000000001865 85.0
TLS3_k127_7889036_2 in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 389.0
TLS3_k127_7889036_20 Alpha galactosidase A - - - 0.0000000000000001476 89.0
TLS3_k127_7889036_21 TIGRFAM RHS repeat-associated core domain - - - 0.00000000001494 76.0
TLS3_k127_7889036_3 Type VI secretion system, TssF K11896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 376.0
TLS3_k127_7889036_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 365.0
TLS3_k127_7889036_5 addiction module antidote protein HigA K07110,K21686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 305.0
TLS3_k127_7889036_6 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006611 268.0
TLS3_k127_7889036_7 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000236 258.0
TLS3_k127_7889036_8 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000002893 226.0
TLS3_k127_7889036_9 addiction module antidote protein HigA K07110,K21686 - - 0.0000000000000000000000000000000000000000000000000000000001651 216.0
TLS3_k127_7903593_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007625 317.0
TLS3_k127_7903593_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07636,K07652 - 2.7.13.3 0.0000000261 66.0
TLS3_k127_7935657_0 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005937 291.0
TLS3_k127_7935657_1 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002871 247.0
TLS3_k127_7935657_2 peptide-methionine (S)-S-oxide reductase activity K07304,K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000003602 237.0
TLS3_k127_7935657_3 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000007267 213.0
TLS3_k127_7935657_4 TatD related DNase - - - 0.00000000001914 68.0
TLS3_k127_7939770_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 454.0
TLS3_k127_7939770_1 PFAM FAD dependent oxidoreductase K15736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008285 448.0
TLS3_k127_7939770_10 Cytochrome c, class I K08738 - - 0.0000000000000000000000000000000000000000000000000000001147 216.0
TLS3_k127_7939770_11 KR domain - - - 0.0000000000000000000000000000000000000000008253 175.0
TLS3_k127_7939770_12 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000001471 164.0
TLS3_k127_7939770_13 N terminal of Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000008231 140.0
TLS3_k127_7939770_14 polysaccharide export K01991,K16552 - - 0.00000000000000000000007175 108.0
TLS3_k127_7939770_15 VanZ like family - - - 0.0000000000000551 85.0
TLS3_k127_7939770_16 PFAM VanZ like family - - - 0.00006916 51.0
TLS3_k127_7939770_2 Nucleotidyl transferase K00978 - 2.7.7.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 355.0
TLS3_k127_7939770_3 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 366.0
TLS3_k127_7939770_4 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 344.0
TLS3_k127_7939770_5 Sugar transferase, PEP-CTERM EpsH1 system associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 317.0
TLS3_k127_7939770_6 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000269 261.0
TLS3_k127_7939770_7 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004179 253.0
TLS3_k127_7939770_8 FemAB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000224 252.0
TLS3_k127_7939770_9 TIGRFAM FemAB-related protein, PEP-CTERM - - - 0.0000000000000000000000000000000000000000000000000000000000004214 225.0
TLS3_k127_7942507_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008964 379.0
TLS3_k127_7942507_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000009176 269.0
TLS3_k127_7942507_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000001837 197.0
TLS3_k127_7942507_3 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000001606 155.0
TLS3_k127_7942507_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K04760 GO:0006139,GO:0006351,GO:0006352,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010604,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031437,GO:0031439,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903311,GO:1903313,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000001222 139.0
TLS3_k127_7942507_5 SMART phosphoesterase PHP domain protein - - - 0.00000000000129 77.0
TLS3_k127_7953947_0 amidohydrolase K01451,K21613 - 3.5.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 319.0
TLS3_k127_7953947_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000005771 148.0
TLS3_k127_7953947_2 Peptidase, M23 - - - 0.0000000000000000000000000001122 128.0
TLS3_k127_7953947_3 signal peptide processing K03100 - 3.4.21.89 0.000000000004334 75.0
TLS3_k127_7963922_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000001625 80.0
TLS3_k127_7963922_2 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.0000002252 56.0
TLS3_k127_7976946_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 618.0
TLS3_k127_7976946_1 Ferritin, Dps family protein K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000007039 259.0
TLS3_k127_7976946_2 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000003335 251.0
TLS3_k127_7976946_3 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000009776 207.0
TLS3_k127_7976946_4 MafB19-like deaminase K01487 - 3.5.4.3 0.0000000000000000000000000000000000000000000000000000004331 200.0
TLS3_k127_7976946_5 receptor - - - 0.000000000000000000000008509 119.0
TLS3_k127_7976946_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000001468 110.0
TLS3_k127_7976946_7 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000001202 59.0
TLS3_k127_7990194_0 alpha-L-arabinofuranosidase - - - 1.019e-300 955.0
TLS3_k127_7990194_2 PFAM Bacterial extracellular solute-binding, family 1 K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 392.0
TLS3_k127_7990194_3 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009704 361.0
TLS3_k127_7990194_4 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 309.0
TLS3_k127_7990194_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000002535 241.0
TLS3_k127_7991079_0 DAHP synthetase I family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 440.0
TLS3_k127_7991079_1 Molecular chaperone. Has ATPase activity K04079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 422.0
TLS3_k127_7991079_10 peptidyl-tyrosine sulfation - - - 0.000000000000000000002628 103.0
TLS3_k127_7991079_2 transcription factor binding K02584,K21009 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 367.0
TLS3_k127_7991079_3 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000001792 211.0
TLS3_k127_7991079_4 Belongs to the DEAD box helicase family K05592,K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000001273 217.0
TLS3_k127_7991079_5 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000000000000000000000002705 200.0
TLS3_k127_7991079_6 metal cluster binding - - - 0.000000000000000000000000000000000000000004986 165.0
TLS3_k127_7991079_7 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000000001766 126.0
TLS3_k127_7991079_8 serine threonine protein kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.0000000000000000000000000005792 130.0
TLS3_k127_7991079_9 Belongs to the ArsC family - - - 0.000000000000000000000000000989 118.0
TLS3_k127_8010675_0 diaminopimelate decarboxylase activity K01586,K12526 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4,4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 515.0
TLS3_k127_8010675_1 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 308.0
TLS3_k127_8010675_2 PA14 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001266 258.0
TLS3_k127_8010675_3 Pfam:DUF303 K05970 - 3.1.1.53 0.00000000000000000000000000000000000007598 151.0
TLS3_k127_8014229_0 xylan catabolic process K03932 - - 0.00000000000000000000000000000000000000000000000000000002779 204.0
TLS3_k127_8014229_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000002179 143.0
TLS3_k127_8014229_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000004251 101.0
TLS3_k127_8015600_0 LUD domain K18929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 455.0
TLS3_k127_8015600_1 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002595 255.0
TLS3_k127_8015600_2 COG1070 Sugar (pentulose and hexulose) K00848 - 2.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000003025 225.0
TLS3_k127_8015600_3 LUD domain K00782 - - 0.0000000000000001574 87.0
TLS3_k127_8015600_4 periplasmic binding protein LacI transcriptional regulator K02529,K03484 - - 0.0000000007334 72.0
TLS3_k127_8015600_5 UTRA K03710 - - 0.000004135 59.0
TLS3_k127_8015600_6 UTRA domain K03710 - - 0.000268 53.0
TLS3_k127_8061393_0 nitrous-oxide reductase activity K00376,K02275 GO:0000041,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0030001,GO:0042597,GO:0044464,GO:0051179,GO:0051234 1.7.2.4,1.9.3.1 1.572e-299 932.0
TLS3_k127_8061393_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 9.414e-221 699.0
TLS3_k127_8061393_10 COG0491 Zn-dependent K01069 - 3.1.2.6 0.00000000000000000001328 93.0
TLS3_k127_8061393_11 transcriptional - - - 0.0000000000000000001984 91.0
TLS3_k127_8061393_12 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000002346 93.0
TLS3_k127_8061393_13 AMP binding - - - 0.00000000000000007856 91.0
TLS3_k127_8061393_14 Protein of unknown function (DUF2892) - - - 0.00000000000007439 73.0
TLS3_k127_8061393_15 - - - - 0.0000000000007206 70.0
TLS3_k127_8061393_16 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000119 63.0
TLS3_k127_8061393_17 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0000000004205 70.0
TLS3_k127_8061393_2 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004152 545.0
TLS3_k127_8061393_3 Transporter DASS family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 439.0
TLS3_k127_8061393_4 Periplasmic copper-binding protein (NosD) K07218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 370.0
TLS3_k127_8061393_5 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00000000000000000000000000000000000000000000000000000000000000000001243 246.0
TLS3_k127_8061393_6 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000004336 239.0
TLS3_k127_8061393_7 ABC-type multidrug transport system ATPase component K19340 - - 0.000000000000000000000000000000000000000000000000007714 192.0
TLS3_k127_8061393_8 Domain of unknown function (DUF4149) - - - 0.0000000000000000000000000000000000000002574 156.0
TLS3_k127_8061393_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000007753 138.0
TLS3_k127_8063412_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 375.0
TLS3_k127_8063412_1 Cytochrome c, class I K08738,K09992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 348.0
TLS3_k127_8063412_2 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000001924 263.0
TLS3_k127_8063412_3 addiction module antidote protein HigA K07110,K21686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000184 256.0
TLS3_k127_8063412_4 PFAM glycoside hydrolase, family 10 K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000000000000000006783 214.0
TLS3_k127_8063412_5 Transcriptional regulator with PAS PAC sensors, AraC family - - - 0.000000000000000000000000000000000000000000000003843 184.0
TLS3_k127_8063412_6 Trehalose utilization protein K09992 - - 0.00000000000000000000000000000000000000000000001528 186.0
TLS3_k127_8063412_7 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000000000000000005125 183.0
TLS3_k127_8063412_8 -acetyltransferase - - - 0.0000000000000002596 85.0
TLS3_k127_8074219_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 461.0
TLS3_k127_8074219_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 359.0
TLS3_k127_8074219_10 ATPases associated with a variety of cellular activities - - - 0.00000000005195 67.0
TLS3_k127_8074219_11 C-type lectin (CTL) or carbohydrate-recognition domain (CRD) - - - 0.00000005734 63.0
TLS3_k127_8074219_12 ABC transporter K06158 - - 0.0002695 49.0
TLS3_k127_8074219_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000001835 299.0
TLS3_k127_8074219_3 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000006459 270.0
TLS3_k127_8074219_4 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000004825 241.0
TLS3_k127_8074219_5 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000001601 213.0
TLS3_k127_8074219_6 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000007092 218.0
TLS3_k127_8074219_7 Peptidase propeptide and YPEB domain K01399 - 3.4.24.26 0.000000000000000000000000000000000000000000000000004572 210.0
TLS3_k127_8074219_8 PA14 domain - - - 0.000000000000000000000000000000000000000002424 181.0
TLS3_k127_8074219_9 - - - - 0.000000000000000007285 95.0
TLS3_k127_8097764_0 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K00372 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 593.0
TLS3_k127_8097764_1 PFAM nitrite and sulphite reductase 4Fe-4S K00366 - 1.7.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 591.0
TLS3_k127_8097764_2 MFS/sugar transport protein K02575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 514.0
TLS3_k127_8097764_3 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component K00380 - 1.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 505.0
TLS3_k127_8097764_4 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 462.0
TLS3_k127_8097764_5 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K15576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001891 290.0
TLS3_k127_8097764_6 Nitrate ABC transporter, ATP-binding protein NtrC K15578 - - 0.0000000000000000000000000000000000000000000000000000004922 207.0
TLS3_k127_8105858_0 Phospholipase D. Active site motifs. K06132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 460.0
TLS3_k127_8105858_1 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006188 391.0
TLS3_k127_8105858_2 ATPase (AAA superfamily K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 347.0
TLS3_k127_8105858_3 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009686 342.0
TLS3_k127_8105858_4 KAP family P-loop domain - - - 0.0007259 45.0
TLS3_k127_81120_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 430.0
TLS3_k127_81120_1 ATPase (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528 391.0
TLS3_k127_81120_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 367.0
TLS3_k127_81120_3 - - - - 0.00000000000000000001422 105.0
TLS3_k127_81120_4 - - - - 0.0000000002034 72.0
TLS3_k127_81120_5 - - - - 0.0002641 51.0
TLS3_k127_8117370_0 pentaerythritol trinitrate reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 558.0
TLS3_k127_8117370_1 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 525.0
TLS3_k127_8117370_2 Enolase C-terminal domain-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 314.0
TLS3_k127_8117370_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 306.0
TLS3_k127_8117370_4 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000001784 151.0
TLS3_k127_8117370_5 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000001248 109.0
TLS3_k127_8139750_0 - - - - 0.0000000000000000000000000000000000000000000000000000006971 201.0
TLS3_k127_8139750_1 spore germination - - - 0.000000000000000000000000000000000000000000000000001912 193.0
TLS3_k127_8139750_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000003818 143.0
TLS3_k127_8139750_3 Putative DNA-binding domain - - - 0.0000000000000000000000009906 114.0
TLS3_k127_8139750_4 Domain of unknown function (DUF4412) - - - 0.0000000000000000000000009977 114.0
TLS3_k127_8139750_5 Transglutaminase/protease-like homologues - - - 0.0000000000003925 82.0
TLS3_k127_8139750_6 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000001039 64.0
TLS3_k127_8147396_0 DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 1.288e-214 684.0
TLS3_k127_8147396_1 Inner membrane protein CreD K06143 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 363.0
TLS3_k127_8147396_2 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000001344 183.0
TLS3_k127_8147396_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000803 168.0
TLS3_k127_8147396_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000311 181.0
TLS3_k127_8147396_5 EamA-like transporter family - - - 0.00000000000000000000000000002134 130.0
TLS3_k127_8147396_6 - - - - 0.0000000000000000918 85.0
TLS3_k127_8158305_0 Alpha amylase, catalytic domain K06044 - 5.4.99.15 1.529e-317 998.0
TLS3_k127_8158305_1 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 320.0
TLS3_k127_8158305_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000106 161.0
TLS3_k127_8158305_3 amine dehydrogenase activity - - - 0.000000000007401 77.0
TLS3_k127_8172989_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 475.0
TLS3_k127_8172989_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 303.0
TLS3_k127_8172989_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000003758 164.0
TLS3_k127_8172989_3 Lipocalin-like domain - - - 0.00003093 54.0
TLS3_k127_8173172_0 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.0000000000000000000000000000000002546 136.0
TLS3_k127_8173172_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000009256 62.0
TLS3_k127_8189568_0 DNA excision - - - 0.0006895 47.0
TLS3_k127_8192850_0 transmembrane transport K13893 - - 1.322e-199 639.0
TLS3_k127_8192850_1 DNA polymerase K02336 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006246 544.0
TLS3_k127_8192850_10 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000006955 182.0
TLS3_k127_8192850_11 SnoaL-like domain - - - 0.00000000000000000000000000000000000000006259 161.0
TLS3_k127_8192850_12 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000004068 139.0
TLS3_k127_8192850_13 HNH endonuclease - - - 0.000000000000000000000000009612 118.0
TLS3_k127_8192850_14 Parallel beta-helix repeat-containing protein - - - 0.00000000000002717 86.0
TLS3_k127_8192850_15 Carboxypeptidase regulatory-like domain - - - 0.00005843 56.0
TLS3_k127_8192850_2 ABC transporter (Permease) K02033,K13894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 442.0
TLS3_k127_8192850_3 metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 354.0
TLS3_k127_8192850_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 310.0
TLS3_k127_8192850_5 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000103 264.0
TLS3_k127_8192850_6 addiction module antidote protein HigA K07110,K21686 - - 0.00000000000000000000000000000000000000000000000000000006167 208.0
TLS3_k127_8192850_7 - - - - 0.000000000000000000000000000000000000000000000000000002229 213.0
TLS3_k127_8192850_8 Shikimate kinase K00851 - 2.7.1.12 0.0000000000000000000000000000000000000000000005656 173.0
TLS3_k127_8192850_9 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000001665 164.0
TLS3_k127_8197680_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 554.0
TLS3_k127_8197680_1 PFAM Divergent AAA domain K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 534.0
TLS3_k127_8197680_2 Belongs to the serpin family K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009204 291.0
TLS3_k127_8197680_3 PIN domain K07062 - - 0.00000000000000000000000000000000000000008246 156.0
TLS3_k127_8197680_4 hyperosmotic response - - - 0.000000000000000000000001152 112.0
TLS3_k127_8197680_5 Belongs to the 'phage' integrase family - - - 0.0000000001566 66.0
TLS3_k127_8201085_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 320.0
TLS3_k127_8201085_1 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 334.0
TLS3_k127_8201085_2 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000398 288.0
TLS3_k127_8201085_3 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000001703 233.0
TLS3_k127_8201085_4 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000001355 238.0
TLS3_k127_8201085_5 Peptidase family M50 K06402 - - 0.0000000000000000000000000000000000003371 149.0
TLS3_k127_8201085_6 HNH endonuclease - - - 0.000000000000000000000000000000000001691 144.0
TLS3_k127_8201085_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0007077 51.0
TLS3_k127_8207264_0 TonB-dependent Receptor Plug Domain K02014,K16088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 551.0
TLS3_k127_8207264_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 406.0
TLS3_k127_8207264_2 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 383.0
TLS3_k127_8207264_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009696 324.0
TLS3_k127_8207264_4 PepSY-associated TM region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002217 282.0
TLS3_k127_8207264_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000001082 219.0
TLS3_k127_8207264_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000002485 77.0
TLS3_k127_8247_0 NAD( ) synthase glutamine-hydrolyzing K01950 - 6.3.5.1 3.097e-213 685.0
TLS3_k127_8247_1 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 353.0
TLS3_k127_8247_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 295.0
TLS3_k127_8247_3 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000119 290.0
TLS3_k127_8247_4 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000001585 200.0
TLS3_k127_8247_5 acyl-coa hydrolase - - - 0.00000000000000000000000000000000004486 139.0
TLS3_k127_8247_6 - - - - 0.0000000000000000000000000000001745 132.0
TLS3_k127_8247_7 Transcriptional regulator - - - 0.00000000000000001589 95.0
TLS3_k127_8247378_0 PFAM cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 328.0
TLS3_k127_8247378_1 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 291.0
TLS3_k127_8247378_2 addiction module antidote protein HigA K07110,K21686 - - 0.0000000000000000000000000000000000000000000003654 177.0
TLS3_k127_8247378_3 ferredoxin-NADP+ reductase activity - - - 0.000000000000000000000000000000000000005197 154.0
TLS3_k127_8247378_4 cytochrome c biogenesis protein K00523 - 1.17.1.1 0.0000000000000000000000000000000000000909 156.0
TLS3_k127_8247378_5 - - - - 0.000000001051 70.0
TLS3_k127_8291416_0 peptidase activity, acting on L-amino acid peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 404.0
TLS3_k127_8291416_1 cyclic nucleotide binding K01420,K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000471 234.0
TLS3_k127_8291416_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000001887 149.0
TLS3_k127_8291416_3 PASTA K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000000000000005606 87.0
TLS3_k127_8291416_4 - - - - 0.000002436 52.0
TLS3_k127_8295813_0 Belongs to the heme-copper respiratory oxidase family K15862 - 1.9.3.1 7.25e-312 969.0
TLS3_k127_8295813_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 394.0
TLS3_k127_8295813_10 Transcriptional regulator, BadM Rrf2 family - - - 0.00000000000000002774 87.0
TLS3_k127_8295813_11 Iron permease FTR1 family K07243 - - 0.0000000000007928 76.0
TLS3_k127_8295813_12 Cytochrome oxidase maturation protein - - - 0.0000007924 55.0
TLS3_k127_8295813_14 FixH K09926 - - 0.0004252 49.0
TLS3_k127_8295813_2 Aldehyde dehydrogenase family K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 386.0
TLS3_k127_8295813_3 alcohol dehydrogenase K18120,K19954 - 1.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 370.0
TLS3_k127_8295813_4 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 358.0
TLS3_k127_8295813_5 TIGRFAM cytochrome c oxidase accessory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 324.0
TLS3_k127_8295813_6 COG2217 Cation transport ATPase K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000727 271.0
TLS3_k127_8295813_7 aldo keto reductase - - - 0.000000000000000000000000000000000000007225 147.0
TLS3_k127_8295813_8 PFAM Cytochrome c, class I K00406 - - 0.000000000000000000000000000000000004152 145.0
TLS3_k127_8295813_9 PA14 domain - - - 0.000000000000000000000000001896 130.0
TLS3_k127_8319465_0 type VI secretion protein K11891 - - 0.00000000000000000000000000000000000000000000000000000006156 225.0
TLS3_k127_8319465_1 Type VI secretion system protein DotU K11892 - - 0.000000000000000000000000004147 121.0
TLS3_k127_8319465_2 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ K11910 - - 0.00000000000000002775 88.0
TLS3_k127_8391061_0 cell wall binding repeat-containing protein - - - 0.000000000000464 84.0
TLS3_k127_8409556_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1187.0
TLS3_k127_8409556_1 Multicopper oxidase - - - 7.582e-197 625.0
TLS3_k127_8409556_2 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000003255 134.0
TLS3_k127_8409556_3 NnrS protein K07234 - - 0.0000000000000000000003236 110.0
TLS3_k127_8409556_4 nitrous oxide K19341 - - 0.000000000000000001566 86.0
TLS3_k127_8420591_0 Superfamily II DNA RNA helicases, SNF2 family - - - 1.834e-270 861.0
TLS3_k127_8420591_1 isoleucyl-tRNA aminoacylation K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 2.799e-219 688.0
TLS3_k127_8420591_10 - - - - 0.000002042 53.0
TLS3_k127_8420591_11 Helicase conserved C-terminal domain - - - 0.000003299 60.0
TLS3_k127_8420591_12 Heat shock protein DnaJ domain protein - - - 0.000007785 58.0
TLS3_k127_8420591_13 PFAM Phage derived protein Gp49-like (DUF891) - - - 0.0000122 48.0
TLS3_k127_8420591_14 Ribbon-helix-helix protein, copG family - - - 0.0002316 45.0
TLS3_k127_8420591_2 Putative DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 448.0
TLS3_k127_8420591_3 Histidine Phosphotransfer domain K05962 - 2.7.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 451.0
TLS3_k127_8420591_4 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 302.0
TLS3_k127_8420591_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000001272 169.0
TLS3_k127_8420591_6 Phage derived protein Gp49-like (DUF891) - - - 0.000000000000001359 78.0
TLS3_k127_8420591_7 - - - - 0.00000000000001387 79.0
TLS3_k127_8420591_8 Helicase conserved C-terminal domain - - - 0.000000009912 68.0
TLS3_k127_8420591_9 PEP-CTERM motif - - - 0.00000004329 63.0
TLS3_k127_8454121_0 Phosphorylase superfamily K01243 - 3.2.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007296 275.0
TLS3_k127_8454121_1 L-threonylcarbamoyladenylate synthase K07566 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.7.87 0.00000000000000000000000001007 115.0
TLS3_k127_8454121_2 Multicopper oxidase - - - 0.00000000000000000000000001277 123.0
TLS3_k127_8477097_0 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 434.0
TLS3_k127_8477097_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000743 226.0
TLS3_k127_8477097_2 nuclear chromosome segregation K03546 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000002464 153.0
TLS3_k127_8576124_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 505.0
TLS3_k127_8576124_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 471.0
TLS3_k127_8576124_10 Belongs to the MraZ family K03925 - - 0.0000000000000002659 85.0
TLS3_k127_8576124_11 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000001192 74.0
TLS3_k127_8576124_12 Cell division protein FtsQ K03589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.000006838 58.0
TLS3_k127_8576124_2 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity K01929,K15792 - 6.3.2.10,6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006697 409.0
TLS3_k127_8576124_3 UDP-N-acetylmuramate-L-alanine ligase activity K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 403.0
TLS3_k127_8576124_4 serine threonine protein kinase K03587,K08384,K08724,K12132,K12552,K12556 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 2.7.11.1,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 350.0
TLS3_k127_8576124_5 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 329.0
TLS3_k127_8576124_6 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 334.0
TLS3_k127_8576124_7 Belongs to the SEDS family K03588 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004916 291.0
TLS3_k127_8576124_8 rRNA processing K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000008339 271.0
TLS3_k127_8576124_9 peptidyl-prolyl cis-trans isomerase activity K01802,K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000003336 219.0
TLS3_k127_8579646_0 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008418 460.0
TLS3_k127_8579646_1 ATP-binding region, ATPase domain protein domain protein K00384,K01338,K11527 - 1.8.1.9,2.7.13.3,3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 317.0
TLS3_k127_8579646_10 Domain of unknown function (DUF4982) K01190 - 3.2.1.23 0.000000000000000000000000000001017 143.0
TLS3_k127_8579646_11 Glucose / Sorbosone dehydrogenase - - - 0.000001782 63.0
TLS3_k127_8579646_12 long-chain fatty acid transport protein K06076 - - 0.000001909 60.0
TLS3_k127_8579646_2 PFAM MotA TolQ ExbB proton channel K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002271 278.0
TLS3_k127_8579646_3 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000001112 236.0
TLS3_k127_8579646_4 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000001184 226.0
TLS3_k127_8579646_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K00557,K03215 - 2.1.1.190,2.1.1.35 0.000000000000000000000000000000000000000000000000000000000003556 224.0
TLS3_k127_8579646_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000006059 202.0
TLS3_k127_8579646_7 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000001332 197.0
TLS3_k127_8579646_8 PA14 domain - - - 0.0000000000000000000000000000001538 137.0
TLS3_k127_8579646_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000001721 136.0
TLS3_k127_860579_0 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000472 226.0
TLS3_k127_860579_1 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000006564 87.0
TLS3_k127_860579_2 repeat protein - - - 0.000008362 59.0
TLS3_k127_873491_0 obsolete transcription factor activity, core RNA polymerase II binding K02945,K03527,K12132 GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 2.535e-196 621.0
TLS3_k127_873491_1 Peptidase family C25 - - - 0.000000000000000000000000000000000000000000000000000000000003256 239.0
TLS3_k127_873491_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000001251 185.0
TLS3_k127_878805_0 Carbamoyl-phosphate synthetase large chain oligomerisation K01955 - 6.3.5.5 0.0 1052.0
TLS3_k127_878805_1 cell envelope organization K05807,K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005427 269.0
TLS3_k127_878805_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000005344 221.0
TLS3_k127_878805_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000004134 128.0
TLS3_k127_878805_4 SseB protein C-terminal domain - - - 0.00000000000000001013 93.0
TLS3_k127_889450_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 387.0
TLS3_k127_889450_1 phosphorelay sensor kinase activity K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 394.0
TLS3_k127_889450_2 metalloendopeptidase activity K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 311.0
TLS3_k127_889450_3 protein-glutamate methylesterase activity K03412,K03413 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000204 157.0
TLS3_k127_896926_0 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 518.0
TLS3_k127_896926_1 DEAD DEAH box helicase domain protein K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 475.0
TLS3_k127_896926_2 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000001689 180.0
TLS3_k127_896926_3 dead DEAH box helicase - - - 0.000000000000000000000000000000000000000000000873 173.0
TLS3_k127_896926_5 - - - - 0.00000000001205 72.0
TLS3_k127_896926_6 cobalamin binding K22491 - - 0.0000000009617 66.0
TLS3_k127_896926_8 Cro/C1-type HTH DNA-binding domain - - - 0.00001442 49.0
TLS3_k127_897186_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1358.0
TLS3_k127_897186_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 382.0
TLS3_k127_897186_2 Iron-containing redox enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 345.0
TLS3_k127_897186_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 351.0
TLS3_k127_897186_4 Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000003576 164.0
TLS3_k127_897186_5 AdoMet dependent proline di-methyltransferase - - - 0.00000000000000001251 85.0
TLS3_k127_920749_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 3.39e-239 754.0
TLS3_k127_920749_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 486.0
TLS3_k127_920749_10 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000004902 226.0
TLS3_k127_920749_11 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000002894 221.0
TLS3_k127_920749_13 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.0000000000000000000000000000000000000000000004115 170.0
TLS3_k127_920749_14 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000001215 167.0
TLS3_k127_920749_15 Methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000005015 150.0
TLS3_k127_920749_16 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000788 122.0
TLS3_k127_920749_17 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000001185 129.0
TLS3_k127_920749_18 PFAM Glycosyl transferase, group 1 K12994 - 2.4.1.349 0.0000000000000000000003737 109.0
TLS3_k127_920749_19 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000005507 97.0
TLS3_k127_920749_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 463.0
TLS3_k127_920749_20 transport system, permease component K01992 - - 0.00000000000000000001755 102.0
TLS3_k127_920749_21 antisigma factor binding K02660,K04749 - - 0.00000000000005556 86.0
TLS3_k127_920749_22 VanZ like family - - - 0.00000000001699 72.0
TLS3_k127_920749_23 Peptidase S16, lon domain protein K07157 - - 0.000000000427 70.0
TLS3_k127_920749_24 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.00000001807 68.0
TLS3_k127_920749_25 PspC domain - - - 0.00000002815 59.0
TLS3_k127_920749_26 MORN repeat variant - - - 0.00009042 53.0
TLS3_k127_920749_27 Peptidase family S41 - - - 0.0002895 52.0
TLS3_k127_920749_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 367.0
TLS3_k127_920749_4 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 315.0
TLS3_k127_920749_5 geranylgeranyl reductase activity K06444,K17830 - 1.3.1.101,1.3.7.11,5.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 317.0
TLS3_k127_920749_6 (ABC) transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 304.0
TLS3_k127_920749_7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000004693 244.0
TLS3_k127_920749_8 beta-N-acetylhexosaminidase activity K01197,K15719 GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005488,GO:0005515,GO:0005975,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015929,GO:0016231,GO:0016787,GO:0016798,GO:0019538,GO:0030246,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901135,GO:1901564 2.3.1.48,3.2.1.169,3.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000001803 239.0
TLS3_k127_920749_9 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000003381 239.0
TLS3_k127_932696_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.391e-307 967.0
TLS3_k127_932696_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.614e-208 674.0
TLS3_k127_932696_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002522 256.0
TLS3_k127_932696_11 ferredoxin-NADP+ reductase activity - - - 0.00000000000000000000000000000000000000000552 165.0
TLS3_k127_932696_12 Cytochrome c K08738 - - 0.00000000000000000000000000000000000000001987 173.0
TLS3_k127_932696_13 - - - - 0.00000000000000000000000000000000000003665 166.0
TLS3_k127_932696_14 peptidoglycan biosynthetic process - - - 0.000000000000000000000000000000008459 145.0
TLS3_k127_932696_15 Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A- site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010035,GO:0010038,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032543,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042221,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046686,GO:0050896,GO:0070125,GO:0071704,GO:0097159,GO:0097367,GO:0140053,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000001081 122.0
TLS3_k127_932696_17 pilus assembly protein PilW K02672 - - 0.00004963 54.0
TLS3_k127_932696_18 Domain of unknown function (DUF4388) - - - 0.00005935 52.0
TLS3_k127_932696_2 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 578.0
TLS3_k127_932696_3 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 509.0
TLS3_k127_932696_4 Pyridine nucleotide-disulphide oxidoreductase K00384,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 374.0
TLS3_k127_932696_5 PFAM glycosyl hydrolase 53 domain protein K01224 - 3.2.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 374.0
TLS3_k127_932696_6 DNA primase activity K02316 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 347.0
TLS3_k127_932696_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001285 296.0
TLS3_k127_932696_8 dTDP-4-dehydrorhamnose reductase K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006656 279.0
TLS3_k127_932696_9 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K07094 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002786 262.0
TLS3_k127_939396_0 PFAM Cytochrome c, class I K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 312.0
TLS3_k127_939396_1 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 294.0
TLS3_k127_939396_2 Uncharacterised protein family (UPF0261) - - - 0.00000000000000000000000000000000007638 136.0
TLS3_k127_939396_3 Phosphoenolpyruvate hydrolase-like - - - 0.00000000000000000000000000007824 127.0
TLS3_k127_939396_4 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000004158 129.0
TLS3_k127_941447_0 Molybdenum cofactor biosynthesis protein K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000005672 207.0
TLS3_k127_941447_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000002396 198.0
TLS3_k127_941447_2 addiction module antidote protein HigA K07110,K21686 - - 0.000000000000000001142 98.0
TLS3_k127_943228_0 RNA polymerase binding - - - 1.27e-289 968.0
TLS3_k127_943228_1 rRNA (adenine-N6,N6-)-dimethyltransferase activity K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000001467 170.0
TLS3_k127_943228_2 TIGRFAM flagellar biosynthetic protein FliS K02422 - - 0.00000000000000000007288 95.0
TLS3_k127_943228_3 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.000000000000007559 89.0
TLS3_k127_943228_4 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03087 - - 0.00007344 45.0
TLS3_k127_947507_0 PFAM Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 421.0
TLS3_k127_947507_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 373.0
TLS3_k127_947507_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000669 167.0
TLS3_k127_947507_11 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000007015 156.0
TLS3_k127_947507_12 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000001554 157.0
TLS3_k127_947507_13 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000006571 152.0
TLS3_k127_947507_14 -acetyltransferase - - - 0.000000000000000000000000000000000001658 147.0
TLS3_k127_947507_15 regulation of translation K03530,K05788 - - 0.000000000000000000000000001803 115.0
TLS3_k127_947507_16 methylamine metabolic process - - - 0.0000000000000000000000003214 114.0
TLS3_k127_947507_17 type I site-specific deoxyribonuclease activity - - - 0.0000000000000000000001664 104.0
TLS3_k127_947507_18 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.000000000000000001137 99.0
TLS3_k127_947507_19 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000006031 71.0
TLS3_k127_947507_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 351.0
TLS3_k127_947507_20 Anaphase-promoting complex subunit K03355 GO:0008150,GO:0031347,GO:0048583,GO:0050789,GO:0065007,GO:0080134 - 0.000000001563 70.0
TLS3_k127_947507_21 Endonuclease/Exonuclease/phosphatase family - - - 0.00001208 58.0
TLS3_k127_947507_3 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 303.0
TLS3_k127_947507_4 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 296.0
TLS3_k127_947507_5 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006482 277.0
TLS3_k127_947507_6 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000001355 265.0
TLS3_k127_947507_7 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K00556,K03218,K03437 - 2.1.1.185,2.1.1.34 0.00000000000000000000000000000000000000000000000000002247 198.0
TLS3_k127_947507_8 Redoxin - - - 0.00000000000000000000000000000000000000000000000000009684 202.0
TLS3_k127_947507_9 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000002748 205.0
TLS3_k127_967789_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.527e-226 709.0
TLS3_k127_967789_1 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008123 354.0
TLS3_k127_967789_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002698 265.0
TLS3_k127_967789_3 Glycosyltransferase like family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000003521 226.0
TLS3_k127_967789_4 Domain of unknown function (DUF4399) - - - 0.00000000000000000001153 100.0
TLS3_k127_967789_5 ATP synthase K02114 - - 0.000000000000000002116 93.0
TLS3_k127_967789_6 Protein of unknown function (DUF1232) - - - 0.000000000006092 72.0
TLS3_k127_967789_7 Bacterial membrane protein, YfhO - - - 0.000000001236 72.0
TLS3_k127_978638_0 NMT1-like family K15576 - - 9.89e-219 686.0
TLS3_k127_978638_1 Binding-protein-dependent transport system inner membrane component K15577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 447.0
TLS3_k127_978638_2 ATPases associated with a variety of cellular activities K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005169 382.0
TLS3_k127_978638_3 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000002376 199.0
TLS3_k127_978638_4 Histidine kinase K20971 - - 0.00000000000000000000000000000000000000000000009732 188.0
TLS3_k127_978638_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000911 179.0
TLS3_k127_978638_6 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000002153 93.0
TLS3_k127_978638_7 TIGRFAM Nitrate transport ATP-binding K15578 - - 0.00000005178 57.0
TLS3_k127_993842_0 Methionine synthase K00548 - 2.1.1.13 0.0 1699.0
TLS3_k127_993842_1 methyltransferase K03892 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000137 261.0
TLS3_k127_993842_2 PDZ domain (Also known as DHR or GLGF) K08372 - - 0.000000000000000000000000000000000000000003541 159.0
TLS3_k127_99688_0 COG0778 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002981 239.0
TLS3_k127_99688_1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.0000000000000000000000000000000000000000000000000007457 192.0
TLS3_k127_99688_2 Transcriptional regulator K07734 - - 0.000000000000000000000000000000000002676 143.0
TLS3_k127_99688_3 Transposase - - - 0.0001036 52.0