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Overview

ID MAG04059
Name TLS3_bin.46
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Limnocylindria
Order Limnocylindrales
Family CSP1-4
Genus SPCO01
Species
Assembly information
Completeness (%) 61.46
Contamination (%) 0.61
GC content (%) 71.0
N50 (bp) 6,901
Genome size (bp) 2,382,981

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2181

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_100551_0 Belongs to the AAA ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 396.0
TLS3_k127_100551_1 SIS domain K00820 - 2.6.1.16 0.000000000000003514 76.0
TLS3_k127_1030912_0 PFAM UDP-glucose GDP-mannose dehydrogenase K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 407.0
TLS3_k127_1030912_1 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000000000000000000000000000000006168 241.0
TLS3_k127_1030912_2 ABC-type polysaccharide polyol phosphate transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000003408 226.0
TLS3_k127_1030912_3 Transport permease protein K01992,K09692 - - 0.000000000000000000000000000000000000007137 157.0
TLS3_k127_1030912_4 synthase K01654 - 2.5.1.56 0.00000000000000000000000000000001618 139.0
TLS3_k127_1030912_5 Macrocin-O-methyltransferase (TylF) - - - 0.00000000000000000001689 105.0
TLS3_k127_1030912_6 - - - - 0.00000001296 68.0
TLS3_k127_1030938_0 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000004166 97.0
TLS3_k127_1049148_0 Aldehyde oxidase and xanthine dehydrogenase a b hammerhead K03520,K11177 - 1.17.1.4,1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 359.0
TLS3_k127_1049148_1 metallochaperone-like domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000003085 252.0
TLS3_k127_1049148_2 Belongs to the arylamine N-acetyltransferase family K00675,K15466 - 2.3.1.118 0.00000000000000000000000000000000000000000000000000000005688 207.0
TLS3_k127_1049148_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000009135 160.0
TLS3_k127_1049148_4 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.0000000000000000000000000000000007867 147.0
TLS3_k127_1049148_5 PFAM regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000007558 110.0
TLS3_k127_1049148_6 Acetyltransferase (GNAT) family - - - 0.000001995 50.0
TLS3_k127_1074598_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 1.987e-271 856.0
TLS3_k127_1077180_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 406.0
TLS3_k127_1077180_1 PFAM DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000001392 134.0
TLS3_k127_1077180_2 Bacterial Ig-like domain K06894 - - 0.0000000000002204 83.0
TLS3_k127_1077180_3 - - - - 0.00001955 52.0
TLS3_k127_1098093_0 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000491 256.0
TLS3_k127_1098093_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000008078 180.0
TLS3_k127_1098093_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.00000000000000000000000000000000008629 138.0
TLS3_k127_1100439_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 5.893e-215 699.0
TLS3_k127_1100439_1 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 306.0
TLS3_k127_1100439_2 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000004097 207.0
TLS3_k127_1100439_3 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.0000000000000000006716 94.0
TLS3_k127_1100439_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.00000000000000001024 97.0
TLS3_k127_1117429_0 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000002522 252.0
TLS3_k127_1117429_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000003375 218.0
TLS3_k127_1117429_2 Daunorubicin resistance abc transporter atpase subunit K01990 - - 0.000000000000000000000000000000002701 131.0
TLS3_k127_1139496_0 Acyl- CoA dehydrogenase type 2 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 546.0
TLS3_k127_1139496_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001214 287.0
TLS3_k127_1149488_0 Aldehyde dehydrogenase family K00130 - 1.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 523.0
TLS3_k127_1149488_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 370.0
TLS3_k127_1149488_2 PFAM Enoyl-CoA hydratase isomerase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000009934 225.0
TLS3_k127_1149488_3 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000002548 226.0
TLS3_k127_1149488_4 MOSC domain containing protein K07140 - - 0.0000000000000000000000000000000000000000000000000000004045 202.0
TLS3_k127_1149488_5 Transcriptional regulator sugar kinase K00845,K00886 - 2.7.1.2,2.7.1.63 0.000000000000000000000000000000000000001944 151.0
TLS3_k127_1149488_6 PFAM NUDIX domain - - - 0.000000000000000000000000000000000000005071 158.0
TLS3_k127_1149488_7 regulation of RNA biosynthetic process - - - 0.00000000000000000000000000008007 121.0
TLS3_k127_1149488_8 PFAM major facilitator superfamily MFS_1 - - - 0.0000000002361 63.0
TLS3_k127_1193691_0 GXGXG motif K00265 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 576.0
TLS3_k127_1221389_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 381.0
TLS3_k127_1221389_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01740,K01761 - 2.5.1.48,2.5.1.49,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 296.0
TLS3_k127_1221389_10 Bacteriocin-protection, YdeI or OmpD-Associated K06878 - - 0.000000000000000000000004545 109.0
TLS3_k127_1221389_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004025 307.0
TLS3_k127_1221389_3 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000063 276.0
TLS3_k127_1221389_4 helix_turn_helix ASNC type K03718 - - 0.000000000000000000000000000000000000000000000001418 183.0
TLS3_k127_1221389_5 ResB-like family K07399 - - 0.00000000000000000000000000000000000000000001093 180.0
TLS3_k127_1221389_6 LysE type translocator - - - 0.0000000000000000000000000000000000000000008485 173.0
TLS3_k127_1221389_7 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.00000000000000000000000000000000001468 149.0
TLS3_k127_1221389_8 diguanylate cyclase - - - 0.000000000000000000000000000000003749 145.0
TLS3_k127_1221389_9 Glutamine synthetase type III N terminal K01915 - 6.3.1.2 0.00000000000000000000000002123 119.0
TLS3_k127_1224287_0 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000002114 232.0
TLS3_k127_1224287_1 Cytidylate kinase-like family K00760 - 2.4.2.8 0.0000000000000000000000000000000644 141.0
TLS3_k127_1224287_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.00000000000000000000001436 115.0
TLS3_k127_1224287_3 Transcriptional regulator K21600 - - 0.000000000000000000002058 98.0
TLS3_k127_1227572_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 2.899e-219 700.0
TLS3_k127_1227572_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000001252 138.0
TLS3_k127_1227572_2 Biotin-requiring enzyme - - - 0.00000000000000278 81.0
TLS3_k127_1227691_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 499.0
TLS3_k127_1227691_1 Bacterial protein of unknown function (DUF839) K07093 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008993 347.0
TLS3_k127_1227691_2 Aminotransferase class-V K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 324.0
TLS3_k127_1227691_3 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000002568 227.0
TLS3_k127_1227691_4 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000008397 157.0
TLS3_k127_1227691_5 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000001681 153.0
TLS3_k127_1227691_7 Histidine phosphatase superfamily (branch 1) K22305 - 3.1.3.3 0.00000000000000000000277 110.0
TLS3_k127_1227691_8 ATPase associated with various cellular activities, AAA_5 K03924 - - 0.000000000000007071 76.0
TLS3_k127_1227691_9 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.0000001465 63.0
TLS3_k127_1247601_0 PFAM AMP-dependent synthetase and ligase K01907 - 6.2.1.16 1.026e-233 741.0
TLS3_k127_1247601_1 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 358.0
TLS3_k127_1247601_10 EamA-like transporter family - - - 0.000000000000000000009859 106.0
TLS3_k127_1247601_2 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 334.0
TLS3_k127_1247601_3 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 343.0
TLS3_k127_1247601_4 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000014 278.0
TLS3_k127_1247601_5 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001972 269.0
TLS3_k127_1247601_6 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000002539 198.0
TLS3_k127_1247601_7 Putative Phosphatase - - - 0.0000000000000000000000000000002261 139.0
TLS3_k127_1247601_8 Belongs to the carbohydrate kinase PfkB family - - - 0.000000000000000000000000004084 119.0
TLS3_k127_1247601_9 Toxic component of a toxin-antitoxin (TA) module K07171 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000006494 106.0
TLS3_k127_1260639_0 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000002845 222.0
TLS3_k127_130242_0 Alpha amylase, catalytic domain - - - 1.831e-289 913.0
TLS3_k127_1306433_0 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000003593 239.0
TLS3_k127_1306433_1 exodeoxyribonuclease I activity - - - 0.0000000000000000000002408 106.0
TLS3_k127_1306433_2 CAAX protease self-immunity - - - 0.00000001509 66.0
TLS3_k127_1311695_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 468.0
TLS3_k127_1311695_1 PFAM glycosyl transferase, family 51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008731 306.0
TLS3_k127_1311695_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003769 275.0
TLS3_k127_1334387_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000001703 235.0
TLS3_k127_1334387_1 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000003951 181.0
TLS3_k127_1334387_2 Fungal trichothecene efflux pump (TRI12) - - - 0.00000000000000000000000000000000000000371 164.0
TLS3_k127_1334387_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000004049 99.0
TLS3_k127_1334387_4 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000007804 61.0
TLS3_k127_1342761_0 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 8.229e-264 831.0
TLS3_k127_1342761_1 ATP dependent DNA ligase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 477.0
TLS3_k127_1342761_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 287.0
TLS3_k127_1342761_3 PFAM peptidase S51 dipeptidase E K05995 - 3.4.13.21 0.0000000000000000000000000000000000000000000000000000000000000000000002887 243.0
TLS3_k127_1342761_4 Domain present in PSD-95, Dlg, and ZO-1/2. K04771,K08070 - 1.3.1.74,3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000001529 249.0
TLS3_k127_1342761_5 response regulator receiver K07658,K07668 - - 0.000000000000000000000000000000000000000000000000000000000000004335 224.0
TLS3_k127_1342761_6 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000001276 204.0
TLS3_k127_1342761_7 Domain of unknown function (DUF4173) - - - 0.00000000000000000000000000000000000007567 162.0
TLS3_k127_1342761_8 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000001869 120.0
TLS3_k127_1342761_9 methyltransferase K00573 - 2.1.1.77 0.000000000000002163 86.0
TLS3_k127_1353122_0 ABC transporter, ATP-binding protein K02028,K02029 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000001943 250.0
TLS3_k127_1353122_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000009704 162.0
TLS3_k127_1373857_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 299.0
TLS3_k127_1373857_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000002178 257.0
TLS3_k127_1391645_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 346.0
TLS3_k127_1391645_1 signal transduction histidine kinase K13587 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 322.0
TLS3_k127_1406762_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 616.0
TLS3_k127_1406762_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000001521 199.0
TLS3_k127_1406762_2 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000003035 100.0
TLS3_k127_1414004_0 helix_turn_helix, Lux Regulon K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 452.0
TLS3_k127_1414004_1 membrane protein of uknown function UCP014873 - - - 0.0000000000000000000000000000000000000002806 153.0
TLS3_k127_1414004_2 - - - - 0.00000000000000000000000000000000005356 145.0
TLS3_k127_1414004_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000001577 88.0
TLS3_k127_1429315_0 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000395 256.0
TLS3_k127_1429315_1 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000001727 202.0
TLS3_k127_1429315_2 geranylgeranyl reductase activity K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000000000009156 202.0
TLS3_k127_1429315_3 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000005939 108.0
TLS3_k127_1429315_4 negative regulation of translational initiation K05554,K15885 - - 0.0000000000000000004075 95.0
TLS3_k127_1431321_0 PFAM Mandelate racemase muconate lactonizing K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 573.0
TLS3_k127_1431321_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009764 282.0
TLS3_k127_1431321_2 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000001601 141.0
TLS3_k127_1431321_3 Endoribonuclease L-PSP - - - 0.00000000000000000000000001121 121.0
TLS3_k127_1431321_4 L-fucose isomerase, C-terminal domain - - - 0.0000004924 60.0
TLS3_k127_146775_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 326.0
TLS3_k127_146775_1 TIGRFAM Translation elongation factor K02355 - - 0.000000000000000000000000000000000000000000000000000000000003027 212.0
TLS3_k127_146775_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000217 184.0
TLS3_k127_146775_3 protein phosphatase 2C domain protein - - - 0.000000000000000000000000009647 123.0
TLS3_k127_146775_4 TIGRFAM TrpR like protein, YerC YecD - - - 0.00000000000000000000183 97.0
TLS3_k127_146775_5 response regulator - - - 0.000000006334 68.0
TLS3_k127_1489599_0 Aminotransferase, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 479.0
TLS3_k127_1499271_0 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000003295 205.0
TLS3_k127_1499271_1 Psort location CytoplasmicMembrane, score K01992 - - 0.000000003481 67.0
TLS3_k127_1515382_0 Trimethylamine methyltransferase (MTTB) - - - 4.745e-207 650.0
TLS3_k127_1515382_1 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000007525 230.0
TLS3_k127_1578494_0 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000005155 175.0
TLS3_k127_1578494_1 Helix-turn-helix domain - - - 0.0001998 54.0
TLS3_k127_1583064_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 343.0
TLS3_k127_1583064_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000003416 196.0
TLS3_k127_1583064_2 cell envelope-related transcriptional attenuator - - - 0.000000000000000000000000000000000000000000000000007042 199.0
TLS3_k127_1583064_3 phospholipase C - - - 0.000000000000000000000000000000000000000000000001582 185.0
TLS3_k127_1583064_4 Cellulose biosynthesis protein BcsQ K02282 - - 0.000000000000000000000000000000000000000000000147 185.0
TLS3_k127_1583064_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963,K03111,K15125 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000006363 112.0
TLS3_k127_1583064_6 Single-stranded DNA-binding protein K03111 - - 0.0000000000000000000000002373 112.0
TLS3_k127_1583064_7 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000005871 93.0
TLS3_k127_1583064_8 Nucleoside K01239 - 3.2.2.1 0.00002074 47.0
TLS3_k127_1623669_0 domain protein K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 463.0
TLS3_k127_1623669_1 Pyridoxal-phosphate dependent enzyme K01883,K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47,6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 387.0
TLS3_k127_1623669_2 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009521 290.0
TLS3_k127_1623669_3 - - - - 0.0000000000000000000000000000000000000000002232 177.0
TLS3_k127_1623669_4 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000001256 146.0
TLS3_k127_1623669_5 ThiS family K03636 - - 0.0000000000000000000001035 103.0
TLS3_k127_1623849_0 L-rhamnose mutarotase K03534 - 5.1.3.32 0.0000000000000000017 93.0
TLS3_k127_1623849_1 L-rhamnose mutarotase K03534 - 5.1.3.32 0.0000000001295 70.0
TLS3_k127_1623849_2 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 0.000000587 61.0
TLS3_k127_1635434_0 PFAM Dak phosphatase K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 367.0
TLS3_k127_1635434_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000131 227.0
TLS3_k127_1635434_2 Protein conserved in bacteria - - - 0.00002252 55.0
TLS3_k127_1635434_3 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0005343 53.0
TLS3_k127_168250_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 431.0
TLS3_k127_168250_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 425.0
TLS3_k127_168250_10 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000006107 109.0
TLS3_k127_168250_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 366.0
TLS3_k127_168250_3 Binding-protein-dependent transport system inner membrane component K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001563 283.0
TLS3_k127_168250_4 PFAM binding-protein-dependent transport systems inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002689 270.0
TLS3_k127_168250_5 PFAM extracellular solute-binding protein family 1 K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009761 262.0
TLS3_k127_168250_6 TIGRFAM competence damage-inducible protein CinA N-terminal domain K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000003402 244.0
TLS3_k127_168250_7 Adenylate K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000001881 246.0
TLS3_k127_168250_8 transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000000000000000000000000000000000000000004765 166.0
TLS3_k127_168250_9 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000001015 166.0
TLS3_k127_1694349_0 nitrite transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002551 293.0
TLS3_k127_1694349_1 Cyclic-di-AMP receptor - - - 0.000000000000000000000000000000004443 131.0
TLS3_k127_1694349_2 PFAM GGDEF domain containing protein - - - 0.00000000000000000000002264 115.0
TLS3_k127_1694349_3 nUDIX hydrolase K01515,K03574,K03801,K08310 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008828,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017144,GO:0018130,GO:0019177,GO:0019438,GO:0019752,GO:0034641,GO:0042364,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0046872,GO:0047429,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.181,3.6.1.13,3.6.1.55,3.6.1.67 0.0000000002894 72.0
TLS3_k127_1694349_4 Anti-sigma-K factor rskA - - - 0.000006732 54.0
TLS3_k127_1782153_0 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 362.0
TLS3_k127_1782153_1 COG2755 Lysophospholipase L1 and related - - - 0.000000000000000000000000000003472 127.0
TLS3_k127_1782153_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000006601 109.0
TLS3_k127_1782153_3 DNA polymerase K02337 - 2.7.7.7 0.00000000000000000000002084 102.0
TLS3_k127_1782153_4 Zincin-like metallopeptidase - - - 0.0000000000000000000002275 102.0
TLS3_k127_1799013_0 purine-nucleoside phosphorylase activity K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 384.0
TLS3_k127_1799013_1 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 319.0
TLS3_k127_1799013_2 Isochorismatase family K08281 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000001269 214.0
TLS3_k127_1799013_3 F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000002081 147.0
TLS3_k127_1799013_4 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000001043 141.0
TLS3_k127_1799013_5 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.000000001749 69.0
TLS3_k127_1805639_0 Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006104,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000009651 202.0
TLS3_k127_1805639_1 Superoxide dismutase K00518 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.15.1.1 0.00000000000000000000000000000000000000003515 166.0
TLS3_k127_1805639_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000003489 61.0
TLS3_k127_1805639_3 n-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000002819 59.0
TLS3_k127_1807281_0 amine oxidase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 358.0
TLS3_k127_1807281_1 synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 357.0
TLS3_k127_1807281_10 - - - - 0.00000000000002649 81.0
TLS3_k127_1807281_11 PspC domain K03973 - - 0.0000000000007392 75.0
TLS3_k127_1807281_12 membrane - - - 0.00000000005759 74.0
TLS3_k127_1807281_13 - - - - 0.0000003065 62.0
TLS3_k127_1807281_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 301.0
TLS3_k127_1807281_3 Putative sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001421 271.0
TLS3_k127_1807281_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009761 263.0
TLS3_k127_1807281_5 Aldose 1-epimerase K01785 - 5.1.3.3 0.00000000000000000000000000000000000000000000000000000000005778 216.0
TLS3_k127_1807281_6 Protein of unknown function (DUF1365) K09701 - - 0.000000000000000000000000000000000000000008844 169.0
TLS3_k127_1807281_7 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000002532 131.0
TLS3_k127_1807281_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K10819 - 2.7.13.3 0.0000000000000000000000000000002418 142.0
TLS3_k127_1826525_0 Aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 602.0
TLS3_k127_1826525_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 401.0
TLS3_k127_1826525_2 PFAM CoA-binding domain protein K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 347.0
TLS3_k127_1826525_3 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000182 269.0
TLS3_k127_1826525_4 Alginate lyase - - - 0.00000000000000000000000000000000000000000001831 179.0
TLS3_k127_1826525_5 Alginate lyase - - - 0.0000000000000000000000000000000001489 153.0
TLS3_k127_1826525_6 WD40 repeat, subgroup - - - 0.00000000000000000000000000000005883 143.0
TLS3_k127_1826525_7 N-acetylmuramoyl-L-alanine amidase - - - 0.0000000000000000000004924 112.0
TLS3_k127_1826525_8 - - - - 0.0000000000000000004025 96.0
TLS3_k127_1826525_9 COG0681 Signal peptidase I K13280 - 3.4.21.89 0.0000000000001669 80.0
TLS3_k127_1848936_0 Asparagine synthase K01953 - 6.3.5.4 9.719e-237 747.0
TLS3_k127_1848936_1 PFAM major facilitator superfamily MFS_1 K08167 - - 1.604e-205 652.0
TLS3_k127_1848936_10 Activator of Hsp90 ATPase 1 family protein - - - 0.0000000000000000000000000004628 124.0
TLS3_k127_1848936_11 PFAM nuclease (SNase K01174 - 3.1.31.1 0.000000000000000000000008617 110.0
TLS3_k127_1848936_12 YCII-related domain - - - 0.00000000000000000002013 95.0
TLS3_k127_1848936_13 O-Antigen ligase - - - 0.0000000004298 72.0
TLS3_k127_1848936_14 Glycosyl transferases group 1 - - - 0.00000005197 55.0
TLS3_k127_1848936_15 Serine hydrolase - - - 0.000009081 50.0
TLS3_k127_1848936_2 Berberine and berberine like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 528.0
TLS3_k127_1848936_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 305.0
TLS3_k127_1848936_4 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000001421 253.0
TLS3_k127_1848936_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000003867 192.0
TLS3_k127_1848936_6 ArsR family transcriptional regulator - - - 0.000000000000000000000000000000000000000003701 157.0
TLS3_k127_1848936_7 Alginate lyase - - - 0.000000000000000000000000000000001002 149.0
TLS3_k127_1848936_8 PFAM MerR family regulatory protein - - - 0.0000000000000000000000000000262 131.0
TLS3_k127_1848936_9 DNA-binding transcription factor activity - - - 0.0000000000000000000000000003105 117.0
TLS3_k127_185389_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000002424 219.0
TLS3_k127_185389_1 PFAM Major Facilitator Superfamily - - - 0.00000000006635 74.0
TLS3_k127_185912_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 603.0
TLS3_k127_185912_1 Thioesterase superfamily - - - 0.00000004816 58.0
TLS3_k127_185912_2 DNA alkylation repair - - - 0.00001081 57.0
TLS3_k127_1934264_0 L-asparaginase II K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000001843 207.0
TLS3_k127_1934264_1 domain protein K03709 - - 0.0000000000000000000000000000001721 136.0
TLS3_k127_1934264_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000001321 64.0
TLS3_k127_194600_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 442.0
TLS3_k127_194600_1 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003168 267.0
TLS3_k127_194600_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000001617 188.0
TLS3_k127_194600_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000004509 76.0
TLS3_k127_194600_4 repeat protein - - - 0.000000000001518 72.0
TLS3_k127_194600_5 EamA-like transporter family - - - 0.00000003243 65.0
TLS3_k127_194600_6 Binds directly to 16S ribosomal RNA K02968 - - 0.00004217 53.0
TLS3_k127_1948206_0 Heat shock 70 kDa protein K04043 - - 3.23e-259 814.0
TLS3_k127_1948206_1 Cation transport protein K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 431.0
TLS3_k127_1948206_2 TrkA-C domain K03499 - - 0.000000000000000000000000000000000000000000002954 168.0
TLS3_k127_1948206_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000217 130.0
TLS3_k127_1948206_4 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000007366 79.0
TLS3_k127_1953855_0 glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 381.0
TLS3_k127_1953855_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 343.0
TLS3_k127_1953855_2 tRNA nucleotidyltransferase domain 2 putative K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 314.0
TLS3_k127_1953855_3 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002845 282.0
TLS3_k127_1953855_4 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000001825 212.0
TLS3_k127_1953855_5 Hydroxymethylglutaryl-CoA lyase K01640 - 4.1.3.4 0.00000000000000000000000000001707 119.0
TLS3_k127_1953855_6 COG0531 Amino acid transporters - - - 0.000000000000000000000004135 117.0
TLS3_k127_1953855_7 ATP dependent DNA ligase domain K01971 - 6.5.1.1 0.000000004099 67.0
TLS3_k127_2002860_0 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 454.0
TLS3_k127_2002860_1 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000006793 114.0
TLS3_k127_2017572_0 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase - - - 1.056e-195 661.0
TLS3_k127_2017572_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009791 461.0
TLS3_k127_2017572_10 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000001404 101.0
TLS3_k127_2017572_11 GAF domain - - - 0.000000000000003073 85.0
TLS3_k127_2017572_12 DNA-binding transcription factor activity - - - 0.0000009638 58.0
TLS3_k127_2017572_13 Na H antiporter K03316 - - 0.00006288 56.0
TLS3_k127_2017572_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 392.0
TLS3_k127_2017572_3 Belongs to the peptidase M24B family K01271,K01274 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 364.0
TLS3_k127_2017572_4 malonyl CoA-acyl carrier protein transacylase K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000008888 251.0
TLS3_k127_2017572_5 Belongs to the peptidase S8 family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000001516 237.0
TLS3_k127_2017572_6 Transmembrane secretion effector - - - 0.0000000000000000000000000000000008038 149.0
TLS3_k127_2017572_7 PFAM Peptidase family M20 M25 M40 - - - 0.000000000000000000000000000000001807 134.0
TLS3_k127_2017572_8 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000000000000000000000000000000281 147.0
TLS3_k127_2017572_9 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.000000000000000000003047 106.0
TLS3_k127_2041312_0 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001405 297.0
TLS3_k127_2041312_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000002884 63.0
TLS3_k127_2041312_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000004927 49.0
TLS3_k127_2112249_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013,K15509 - 1.1.1.23,1.1.1.308 0.00000000000000000000000000000000000000000000000000000000003211 212.0
TLS3_k127_2112249_1 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000004871 212.0
TLS3_k127_2112249_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000001091 204.0
TLS3_k127_2112249_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000001235 158.0
TLS3_k127_2149138_0 Phosphatidylinositol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001437 255.0
TLS3_k127_2149138_1 Protein of unknown function (DUF3090) - - - 0.000000000000000000000000000000000000000000000000000004205 194.0
TLS3_k127_2149138_2 Calcineurin-like phosphoesterase - - - 0.000000000000000000001349 103.0
TLS3_k127_2150016_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 374.0
TLS3_k127_2150016_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000003378 213.0
TLS3_k127_2150016_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067,K01790,K19997 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008831,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 1.1.1.133,5.1.3.13,5.1.3.26 0.0000000000000000000000000000000000000000000000005581 188.0
TLS3_k127_2150016_3 Glyco_18 K01448,K07260,K20276 - 3.4.17.14,3.5.1.28 0.000000000000000000000000000000000000001316 171.0
TLS3_k127_2150016_4 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000001471 131.0
TLS3_k127_2150016_5 Metallo-peptidase family M12 - - - 0.0000000000000008928 91.0
TLS3_k127_2154681_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 4.682e-283 885.0
TLS3_k127_2154681_1 trimethylamine methyltransferase K14083 - 2.1.1.250 2.195e-203 649.0
TLS3_k127_2154681_2 PFAM Glycosyl transferase family 2 K00694 - 2.4.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 507.0
TLS3_k127_2154681_3 dipeptide transport K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 454.0
TLS3_k127_2154681_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 370.0
TLS3_k127_2154681_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 324.0
TLS3_k127_2154681_6 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 325.0
TLS3_k127_2154681_7 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 303.0
TLS3_k127_2154681_8 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000002526 211.0
TLS3_k127_2154681_9 regulator IclR - - - 0.00000000000000000000000000001167 127.0
TLS3_k127_2197069_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 404.0
TLS3_k127_2197069_1 Uroporphyrinogen decarboxylase (URO-D) K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 381.0
TLS3_k127_2228053_0 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000001819 194.0
TLS3_k127_2241209_0 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 298.0
TLS3_k127_2241209_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000004172 229.0
TLS3_k127_2241209_2 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000006959 183.0
TLS3_k127_2241209_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000001532 169.0
TLS3_k127_2272853_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000004723 237.0
TLS3_k127_2272853_1 Cupin - - - 0.00000000000000000000007866 103.0
TLS3_k127_2272853_2 Predicted membrane protein (DUF2207) - - - 0.0000000000000711 75.0
TLS3_k127_2272853_3 ABC-2 family transporter protein K01992 - - 0.000000002982 68.0
TLS3_k127_2272853_4 Phosphotransferase enzyme family K04343 - 2.7.1.72 0.00001857 57.0
TLS3_k127_2323843_0 thiosulfate sulfurtransferase activity K01802,K21028 GO:0003674,GO:0003824,GO:0016740,GO:0016782,GO:0016783 2.8.1.11,5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 394.0
TLS3_k127_2323843_1 Domain of unknown function (DUF4203) - - - 0.000000000000000000000001118 112.0
TLS3_k127_2323843_2 - - - - 0.000000000000000004497 89.0
TLS3_k127_2342971_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 473.0
TLS3_k127_2342971_1 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 388.0
TLS3_k127_2342971_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 316.0
TLS3_k127_2342971_3 F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000001428 202.0
TLS3_k127_2342971_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000002436 189.0
TLS3_k127_2342971_5 Alpha amylase, catalytic domain K05343 - 3.2.1.1,5.4.99.16 0.00000000000000000000000000000000000000000000497 185.0
TLS3_k127_2342971_6 sugar isomerase - - - 0.00000000000000000000000000000000008771 146.0
TLS3_k127_2342971_7 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 GO:0008150,GO:0040007 1.2.1.70 0.0000000000000000000000005137 119.0
TLS3_k127_2342971_8 Helix-turn-helix domain - - - 0.0000000000000000000009198 104.0
TLS3_k127_2364576_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 2.207e-229 737.0
TLS3_k127_2370014_0 Tetratricopeptide repeat - - - 3.07e-207 685.0
TLS3_k127_2370014_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 510.0
TLS3_k127_2370014_11 response regulator - - - 0.00000000001765 70.0
TLS3_k127_2370014_12 Histidine Phosphotransfer domain - - - 0.000000001652 70.0
TLS3_k127_2370014_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 418.0
TLS3_k127_2370014_3 helix_turn_helix, Lux Regulon K02479 - - 0.00000000000000000000000000000000000000000000000000000000000002979 223.0
TLS3_k127_2370014_4 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.00000000000000000000000000000000000000000000008721 173.0
TLS3_k127_2370014_5 Beta-lactamase K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000003225 188.0
TLS3_k127_2370014_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000006536 178.0
TLS3_k127_2370014_7 HhH-GPD superfamily base excision DNA repair protein - - - 0.000000000000000000000000000000000816 135.0
TLS3_k127_2370014_8 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000009863 124.0
TLS3_k127_2404918_0 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008065 308.0
TLS3_k127_2440317_0 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 401.0
TLS3_k127_2440317_1 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 296.0
TLS3_k127_2440317_2 Nucleoside H+ symporter K05820 - - 0.000000000000006065 88.0
TLS3_k127_2451907_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 615.0
TLS3_k127_2451907_1 Belongs to the FtsK SpoIIIE SftA family K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 419.0
TLS3_k127_2451907_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000001423 217.0
TLS3_k127_2468937_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 354.0
TLS3_k127_2468937_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.0000000000000000000000000000000000000000000000000000003246 207.0
TLS3_k127_2472716_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 372.0
TLS3_k127_2472716_1 Exporter of polyketide antibiotics K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 309.0
TLS3_k127_2472716_2 integral membrane protein - - - 0.000000000000000000000000000000002617 140.0
TLS3_k127_2472716_3 regulation of RNA biosynthetic process - - - 0.00000000000000000000000000006084 121.0
TLS3_k127_2474979_0 Binding-protein-dependent transport system inner membrane component K02029,K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002784 280.0
TLS3_k127_2474979_1 Bacterial periplasmic substrate-binding proteins K02030,K02424,K17073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000104 269.0
TLS3_k127_2474979_2 ATPases associated with a variety of cellular activities K02028,K17076 - 3.6.3.21 0.0000000000000000000002894 109.0
TLS3_k127_2482146_0 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000002416 200.0
TLS3_k127_2485141_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 404.0
TLS3_k127_2485141_1 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000001514 201.0
TLS3_k127_2485141_2 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000855 101.0
TLS3_k127_2485141_3 Sodium/hydrogen exchanger family K03316 - - 0.000000000000171 78.0
TLS3_k127_2493282_0 PFAM basic membrane lipoprotein K07335 - - 0.00000000000000000000000000000000000000000003345 177.0
TLS3_k127_2536089_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000002348 235.0
TLS3_k127_2558926_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 417.0
TLS3_k127_2558926_1 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000004534 258.0
TLS3_k127_2559705_0 ketone body catabolic process K01026 - 2.8.3.1 1.693e-212 672.0
TLS3_k127_2559705_1 ABC-type sugar transport system, ATPase component K10441 - 3.6.3.17 4.95e-199 636.0
TLS3_k127_2559705_10 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008776 258.0
TLS3_k127_2559705_11 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000006064 248.0
TLS3_k127_2559705_12 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000002457 233.0
TLS3_k127_2559705_13 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000003855 237.0
TLS3_k127_2559705_14 PFAM ROK family protein K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000001036 227.0
TLS3_k127_2559705_15 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000002822 208.0
TLS3_k127_2559705_16 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000002876 188.0
TLS3_k127_2559705_17 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000006921 199.0
TLS3_k127_2559705_18 AP endonuclease family 2 C terminus - - - 0.000000000000000000003015 93.0
TLS3_k127_2559705_2 Belongs to the aldehyde dehydrogenase family K00141 - 1.2.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 486.0
TLS3_k127_2559705_3 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 353.0
TLS3_k127_2559705_4 Periplasmic binding protein domain K02058,K10439,K17213 GO:0003674,GO:0005215,GO:0005488,GO:0005534,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0015144,GO:0015145,GO:0015749,GO:0015757,GO:0016020,GO:0016021,GO:0022857,GO:0030246,GO:0030288,GO:0030313,GO:0031224,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0044425,GO:0044464,GO:0048029,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009173 329.0
TLS3_k127_2559705_5 Branched-chain amino acid transport system / permease component K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 329.0
TLS3_k127_2559705_6 protein containing SIS (Sugar isomerase) phosphosugar binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 306.0
TLS3_k127_2559705_7 DeoC/LacD family aldolase K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002747 273.0
TLS3_k127_2559705_8 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000486 258.0
TLS3_k127_2559705_9 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000009101 253.0
TLS3_k127_2569303_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 373.0
TLS3_k127_2569303_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001001 241.0
TLS3_k127_2596931_0 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000001767 193.0
TLS3_k127_2596931_1 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000003962 179.0
TLS3_k127_2596931_2 InterPro IPR014922 - - - 0.0000000000000000000000001066 110.0
TLS3_k127_2651726_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 8.853e-260 820.0
TLS3_k127_2651726_1 Phosphomethylpyrimidine kinase - - - 0.000000000000000000000000000000003766 137.0
TLS3_k127_2651726_2 Belongs to the GcvT family K19191 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006575,GO:0006576,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008480,GO:0009056,GO:0009063,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019695,GO:0019752,GO:0019842,GO:0031406,GO:0031974,GO:0033218,GO:0034641,GO:0035999,GO:0036094,GO:0042133,GO:0042135,GO:0042219,GO:0042402,GO:0042426,GO:0042558,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0046653,GO:0046997,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0072341,GO:0097159,GO:0097164,GO:1901052,GO:1901053,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.5.3.19 0.0000000000001147 75.0
TLS3_k127_2653661_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 7.743e-195 624.0
TLS3_k127_2653661_1 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 331.0
TLS3_k127_2653661_10 periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily K02199 - - 0.00000000000000000000000636 108.0
TLS3_k127_2653661_11 Sigma-70, region 4 K03088 - - 0.000000000000000000000007874 109.0
TLS3_k127_2653661_12 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000002579 95.0
TLS3_k127_2653661_13 PFAM zinc finger, DksA TraR C4-type K06204 - - 0.00000000000002471 77.0
TLS3_k127_2653661_14 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000001714 70.0
TLS3_k127_2653661_15 COG2133 Glucose sorbosone dehydrogenases - - - 0.000000003902 68.0
TLS3_k127_2653661_16 - - - - 0.0005726 51.0
TLS3_k127_2653661_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 333.0
TLS3_k127_2653661_3 PFAM binding-protein-dependent transport systems inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 303.0
TLS3_k127_2653661_4 Multidrug ABC transporter ATPase K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008247 253.0
TLS3_k127_2653661_5 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000000000000005115 205.0
TLS3_k127_2653661_6 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02351,K07245 - - 0.00000000000000000000000000000000000000000000000000001048 209.0
TLS3_k127_2653661_7 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000002868 197.0
TLS3_k127_2653661_8 PFAM cytochrome c oxidase subunit III K02276,K02299 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 0.00000000000000000000000000000000000000000004124 173.0
TLS3_k127_2653661_9 TIGRFAM cytochrome c oxidase, subunit II K02275 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.000000000000000000000000000000000001765 153.0
TLS3_k127_2695340_0 Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and or methyl galactoside import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000004796 230.0
TLS3_k127_2695340_1 Belongs to the binding-protein-dependent transport system permease family K10440,K17206 - - 0.000000000000000000000000000000000000000000000000000005437 196.0
TLS3_k127_2695340_2 Periplasmic binding protein LacI transcriptional regulator K02058 - - 0.00000000000000000001574 105.0
TLS3_k127_2699050_0 purine-nucleoside phosphorylase activity K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 310.0
TLS3_k127_2699050_1 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000000000008185 225.0
TLS3_k127_2699050_2 FR47-like protein - - - 0.0000000000000000000008608 106.0
TLS3_k127_2705157_0 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000007331 188.0
TLS3_k127_2705157_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000001174 62.0
TLS3_k127_2708932_0 Sporulation and spore germination - - - 0.000000000000000000000000000000000000000000000000000002638 207.0
TLS3_k127_2708932_1 - - - - 0.000000001132 70.0
TLS3_k127_2708932_2 - - - - 0.0004405 51.0
TLS3_k127_2712435_0 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000002633 209.0
TLS3_k127_2712435_1 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000001746 186.0
TLS3_k127_2712435_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00001272 57.0
TLS3_k127_2712435_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000001212 166.0
TLS3_k127_2712435_3 Cytochrome b/b6/petB K03891 - - 0.0000000000000000000000000000000000000001093 151.0
TLS3_k127_2712435_4 Rieske 2Fe-2S - - - 0.000000000000000000000001302 111.0
TLS3_k127_2712435_5 Rhodanese Homology Domain - - - 0.00000000000000000000114 100.0
TLS3_k127_2712435_6 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000001624 93.0
TLS3_k127_2712435_7 PFAM Protein kinase - - - 0.00000003164 66.0
TLS3_k127_2712435_8 PFAM blue (type 1) copper domain protein - - - 0.0000007602 61.0
TLS3_k127_2712435_9 Domain of unknown function (DUF309) K09763 - - 0.000001577 61.0
TLS3_k127_2730204_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 415.0
TLS3_k127_2730204_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 402.0
TLS3_k127_2743054_0 Inosine-uridine preferring nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 330.0
TLS3_k127_2743054_1 Psort location CytoplasmicMembrane, score K02006,K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 310.0
TLS3_k127_2743054_2 Cobalt transport protein K16785 - - 0.000000000000000000000000000000000000000000008364 172.0
TLS3_k127_2743054_3 phosphorelay sensor kinase activity K16923,K18967 - 2.7.7.65 0.000000000000000000000000000321 128.0
TLS3_k127_2743054_4 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000003584 100.0
TLS3_k127_2743054_5 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000004737 101.0
TLS3_k127_2748620_0 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001079 288.0
TLS3_k127_2748620_1 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001122 298.0
TLS3_k127_2748620_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000001283 212.0
TLS3_k127_2748620_3 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000002625 208.0
TLS3_k127_2748620_4 PFAM band 7 protein - - - 0.00000001182 67.0
TLS3_k127_2772431_0 PFAM single-stranded nucleic acid binding R3H domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 573.0
TLS3_k127_2772431_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 444.0
TLS3_k127_2772431_2 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002105 241.0
TLS3_k127_2772431_3 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000002266 224.0
TLS3_k127_2772431_4 amine dehydrogenase activity K17285 - - 0.000001104 50.0
TLS3_k127_2772431_5 - - - - 0.000009747 58.0
TLS3_k127_2804459_0 Transport permease protein K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 308.0
TLS3_k127_2804459_1 uracil-DNA glycosylase K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000006274 244.0
TLS3_k127_2804459_2 Transport permease protein K09694 - - 0.000000000000000000000000327 108.0
TLS3_k127_2809408_0 AAA ATPase domain - - - 8.542e-198 644.0
TLS3_k127_2809408_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K05555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 318.0
TLS3_k127_2809408_2 Short-chain dehydrogenase reductase sdr K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 291.0
TLS3_k127_2816653_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009399 348.0
TLS3_k127_2816653_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000005751 191.0
TLS3_k127_2816653_10 - - - - 0.0004034 51.0
TLS3_k127_2816653_2 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000652 158.0
TLS3_k127_2816653_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000002197 147.0
TLS3_k127_2816653_4 PFAM GDSL-like Lipase Acylhydrolase - - - 0.000000000000000000000000000000004634 137.0
TLS3_k127_2816653_5 PFAM Uncharacterised protein family UPF0079, ATPase K06925 - - 0.00000000000000000000000000005459 123.0
TLS3_k127_2816653_6 Universal bacterial protein YeaZ K14742 - - 0.000000000000005239 86.0
TLS3_k127_2816653_7 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000006044 60.0
TLS3_k127_2816653_8 - - - - 0.000009792 57.0
TLS3_k127_2816653_9 Carbohydrate kinase - - - 0.00006936 55.0
TLS3_k127_2831481_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 334.0
TLS3_k127_2832362_0 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 423.0
TLS3_k127_2832362_1 Peptidase inhibitor I9 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007126 326.0
TLS3_k127_2832362_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000229 244.0
TLS3_k127_2832362_3 cyclic nucleotide binding - - - 0.000000000000000000000000000000000000000004351 175.0
TLS3_k127_2842405_0 PFAM ATPase associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 412.0
TLS3_k127_2842405_1 belongs to the aldehyde dehydrogenase family K09472,K12254 - 1.2.1.54,1.2.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 343.0
TLS3_k127_2842405_2 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000006531 236.0
TLS3_k127_2842405_3 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000001032 243.0
TLS3_k127_2860571_0 COG0004 Ammonia permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 608.0
TLS3_k127_2860571_1 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 343.0
TLS3_k127_2860571_10 - - - - 0.000001234 53.0
TLS3_k127_2860571_11 MacB-like periplasmic core domain K02004 - - 0.0001036 50.0
TLS3_k127_2860571_2 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002915 284.0
TLS3_k127_2860571_3 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000005743 214.0
TLS3_k127_2860571_4 Lysine methyltransferase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010565,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018023,GO:0018193,GO:0018205,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031974,GO:0031998,GO:0031999,GO:0032259,GO:0036211,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0043467,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045833,GO:0045922,GO:0046320,GO:0046322,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050994,GO:0050995,GO:0051341,GO:0051354,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1904732,GO:1904733,GO:1904735,GO:1904736 - 0.00000000000000000000000000000000000000000000000000000000000907 215.0
TLS3_k127_2860571_5 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000008181 168.0
TLS3_k127_2860571_6 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000001044 138.0
TLS3_k127_2860571_7 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000007239 135.0
TLS3_k127_2860571_8 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000001186 104.0
TLS3_k127_2860571_9 Glutamine amidotransferase domain K22081 - 2.1.1.21 0.0000000158 64.0
TLS3_k127_2867095_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000007673 222.0
TLS3_k127_2867095_1 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000002071 146.0
TLS3_k127_2879373_0 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 303.0
TLS3_k127_2879373_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000003506 225.0
TLS3_k127_2879373_2 - - - - 0.000000000000000000000000000000000000000000000000004218 187.0
TLS3_k127_2879373_3 carbon dioxide binding K04653 - - 0.0000000813 59.0
TLS3_k127_2883835_0 glycine cleavage T protein (aminomethyl transferase) K19191 - 1.5.3.19 5.478e-204 668.0
TLS3_k127_2883835_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.946e-199 634.0
TLS3_k127_2883835_2 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 451.0
TLS3_k127_2883835_3 TIGRFAM 6-phosphogluconate dehydrogenase, decarboxylating K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 385.0
TLS3_k127_2883835_4 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000001821 179.0
TLS3_k127_2883835_5 glucose 6-phosphate dehydrogenase - - - 0.000000000000000000192 102.0
TLS3_k127_2892862_0 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 412.0
TLS3_k127_2892862_1 part of an ABC transporter complex. Responsible for energy coupling to the transport system K16785,K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 356.0
TLS3_k127_2892862_2 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000008832 233.0
TLS3_k127_2892862_3 cobalt transport K16785 - - 0.0000000000000000000000006626 115.0
TLS3_k127_2894046_0 TIGRFAM phenylacetate-CoA oxygenase, PaaG subunit K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 419.0
TLS3_k127_2894046_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000003901 166.0
TLS3_k127_2894046_2 phenylacetate catabolic process K02610 - - 0.0000000000000000001092 94.0
TLS3_k127_2956199_0 1,4-alpha-glucan branching enzyme K00700 - 2.4.1.18 4.261e-248 803.0
TLS3_k127_2956199_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000157 278.0
TLS3_k127_2956199_2 3-methyladenine DNA glycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000001699 237.0
TLS3_k127_2956199_3 Cupin superfamily (DUF985) K09705 - - 0.000000000000000000000000000000000000000001873 172.0
TLS3_k127_2956199_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000002164 168.0
TLS3_k127_2956199_5 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000005992 141.0
TLS3_k127_2956199_6 Lytic transglycolase - - - 0.000000000000000000001348 106.0
TLS3_k127_2956199_7 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000004816 79.0
TLS3_k127_2957565_0 Alcohol dehydrogenase GroES-like domain K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 482.0
TLS3_k127_2957565_1 Cys/Met metabolism PLP-dependent enzyme K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 473.0
TLS3_k127_2957565_2 PHP domain K04486 - 3.1.3.15 0.0000000000000000000000000000000002349 143.0
TLS3_k127_2957565_3 hydrolase activity - - - 0.000000009175 56.0
TLS3_k127_2967966_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 9.344e-245 771.0
TLS3_k127_2967966_1 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 394.0
TLS3_k127_2967966_10 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.000000000000003309 87.0
TLS3_k127_2967966_11 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000005136 53.0
TLS3_k127_2967966_13 PFAM Peptidoglycan-binding LysM - - - 0.0001362 54.0
TLS3_k127_2967966_2 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 381.0
TLS3_k127_2967966_3 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 329.0
TLS3_k127_2967966_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 333.0
TLS3_k127_2967966_5 PFAM isocitrate isopropylmalate dehydrogenase K00030,K07246 - 1.1.1.41,1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 305.0
TLS3_k127_2967966_6 Penicillin-binding Protein dimerisation domain K03587,K08384 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000003018 266.0
TLS3_k127_2967966_7 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000001782 142.0
TLS3_k127_2967966_8 Reverse transcriptase-like K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.0000000000000000000000000000001829 134.0
TLS3_k127_2967966_9 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.000000000000000000000002727 112.0
TLS3_k127_296935_0 DEAD DEAH box K03724 - - 1.994e-244 771.0
TLS3_k127_2991095_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 6.2.1.1 1.93e-217 681.0
TLS3_k127_2991095_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 513.0
TLS3_k127_2991095_2 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 382.0
TLS3_k127_2991095_3 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000003084 218.0
TLS3_k127_2991095_4 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000004664 205.0
TLS3_k127_2991095_5 Protein of unknown function (DUF1269) - - - 0.000002012 57.0
TLS3_k127_2998130_0 Belongs to the FGGY kinase family - - - 0.0000000000000000000005153 103.0
TLS3_k127_2998130_1 EamA-like transporter family - - - 0.0000000000000000001969 101.0
TLS3_k127_2998130_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000001675 71.0
TLS3_k127_3016528_0 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 440.0
TLS3_k127_3016528_1 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000007159 234.0
TLS3_k127_3016528_2 Metallopeptidase family M24 - - - 0.00000000000002172 72.0
TLS3_k127_3049385_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 456.0
TLS3_k127_3049385_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 421.0
TLS3_k127_3049385_2 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002809 292.0
TLS3_k127_3049385_3 Uncharacterized protein family (UPF0051) K07033,K09014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003819 272.0
TLS3_k127_3049385_4 Sodium Bile acid symporter family - - - 0.0000007668 62.0
TLS3_k127_3063673_0 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 452.0
TLS3_k127_3063673_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 385.0
TLS3_k127_3063673_2 PFAM binding-protein-dependent transport systems inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000606 256.0
TLS3_k127_3063673_3 ABC-type spermidine putrescine transport system, permease component II K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000002172 244.0
TLS3_k127_3063673_4 Bacterial extracellular solute-binding protein K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000005227 252.0
TLS3_k127_3063673_5 PFAM Rieske 2Fe-2S domain protein K00479,K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000004089 198.0
TLS3_k127_3066137_0 Dihydropyrimidinase K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 614.0
TLS3_k127_3066137_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000002911 186.0
TLS3_k127_3066137_2 Histidine kinase-like ATPase domain - - - 0.0000000001644 74.0
TLS3_k127_3083439_0 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 330.0
TLS3_k127_3083439_1 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.000000000000000000000000000000000000000000000000000007325 201.0
TLS3_k127_3083439_2 Electron transfer flavoprotein K03522 - - 0.000000000000000001266 94.0
TLS3_k127_3085015_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 311.0
TLS3_k127_3085015_1 Stage II sporulation protein E (SpoIIE) - - - 0.00000000000000000000000000000002759 132.0
TLS3_k127_3085015_2 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000005369 109.0
TLS3_k127_3089993_0 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005814 376.0
TLS3_k127_3089993_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 368.0
TLS3_k127_3089993_10 Endonuclease/Exonuclease/phosphatase family K18764 - 3.1.13.4 0.00000000000000000004923 103.0
TLS3_k127_3089993_11 transcriptional regulator K03892 - - 0.000000000000000001359 94.0
TLS3_k127_3089993_12 Phosphoglycerate mutase family K08296 - - 0.000000000000002151 83.0
TLS3_k127_3089993_2 phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 349.0
TLS3_k127_3089993_3 Putative RNA methylase family UPF0020 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 316.0
TLS3_k127_3089993_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954 303.0
TLS3_k127_3089993_5 PFAM Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001924 252.0
TLS3_k127_3089993_6 low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000287 164.0
TLS3_k127_3089993_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000001084 166.0
TLS3_k127_3089993_8 protein histidine kinase activity K02484,K07636,K07768 - 2.7.13.3 0.000000000000000000000000000000000000002052 151.0
TLS3_k127_3089993_9 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000002091 102.0
TLS3_k127_3102612_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335,K05587,K18331 - 1.12.1.3,1.6.5.3 1.21e-206 661.0
TLS3_k127_3102612_1 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 340.0
TLS3_k127_3102612_2 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K05299,K05588 - 1.17.1.10,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002173 292.0
TLS3_k127_3102612_3 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14128,K18007 - 1.12.1.2,1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000004916 229.0
TLS3_k127_3102612_4 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K05586 - 1.6.5.3 0.000000000000000000000000000000000000001966 149.0
TLS3_k127_3124539_0 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 494.0
TLS3_k127_3124539_1 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000003392 233.0
TLS3_k127_3126152_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 546.0
TLS3_k127_3126152_1 DRTGG domain K06873 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000779 256.0
TLS3_k127_3126152_2 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000007435 199.0
TLS3_k127_3126152_3 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000001936 180.0
TLS3_k127_3126152_4 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000001036 176.0
TLS3_k127_3137462_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 494.0
TLS3_k127_3137462_1 Belongs to the formate--tetrahydrofolate ligase family K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009233 467.0
TLS3_k127_3137462_10 Dodecin K09165 - - 0.0000007194 59.0
TLS3_k127_3137462_11 - - - - 0.0002911 52.0
TLS3_k127_3137462_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K14161 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 375.0
TLS3_k127_3137462_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001648 266.0
TLS3_k127_3137462_4 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000114 194.0
TLS3_k127_3137462_5 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000003625 130.0
TLS3_k127_3137462_6 Probable zinc-ribbon domain - - - 0.00000000000000000000000000003068 130.0
TLS3_k127_3137462_7 PFAM Formiminotransferase-cyclodeaminase - - - 0.000000000000000000000000001628 125.0
TLS3_k127_3137462_8 chaperone-mediated protein folding - - - 0.000000006556 70.0
TLS3_k127_3137462_9 Protein of unknown function (DUF1232) - - - 0.00000001549 64.0
TLS3_k127_3173158_0 Glycosyltransferase 36 associated - - - 9.503e-247 804.0
TLS3_k127_3173158_1 PFAM glycoside hydrolase family 39 K01198 - 3.2.1.37 0.000000000000000000000000000000000000000000000000000000000000000000052 237.0
TLS3_k127_3173158_2 Response regulator receiver - - - 0.000000000000000000000000000000000000005274 155.0
TLS3_k127_3173158_3 self proteolysis - - - 0.00000000000000000000000000000002896 134.0
TLS3_k127_3244496_0 PFAM Helicase conserved C-terminal domain K06877 - - 3.283e-202 651.0
TLS3_k127_3244496_1 Flotillin K07192 - - 0.00000000000000000000000000000000000000000000000000001959 203.0
TLS3_k127_3244496_2 - - - - 0.0000001623 61.0
TLS3_k127_3247749_0 Belongs to the binding-protein-dependent transport system permease family K02057,K10440 - - 0.00000000000000000000000000000000000000000000000000000009785 204.0
TLS3_k127_3247749_1 Periplasmic binding protein-like domain K02529 - - 0.0000000000000000000000000000000000000000008956 166.0
TLS3_k127_3248196_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 619.0
TLS3_k127_3257892_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 527.0
TLS3_k127_3257892_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 364.0
TLS3_k127_3257892_2 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007071 291.0
TLS3_k127_3257892_3 Activator of Hsp90 ATPase - - - 0.00000000000000000000000000000000000000000000000002045 196.0
TLS3_k127_3257892_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000003888 119.0
TLS3_k127_3262931_0 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 387.0
TLS3_k127_3262931_1 PFAM UDP-glucose GDP-mannose dehydrogenase K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 352.0
TLS3_k127_3262931_2 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000008663 248.0
TLS3_k127_3262931_3 Bacterial transferase hexapeptide - - - 0.0000000000000000000000000000000000000000000000000000002016 209.0
TLS3_k127_3262931_4 Protein of unknown function (DUF3048) C-terminal domain - - - 0.00000000000000000000000000000000000000000223 179.0
TLS3_k127_326427_0 PFAM MMPL domain protein K06994 - - 1.029e-195 635.0
TLS3_k127_326427_1 Lipocalin-like domain - - - 0.00000000000000000000001067 107.0
TLS3_k127_326427_2 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.0001816 53.0
TLS3_k127_3293353_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 450.0
TLS3_k127_3317737_0 4Fe-4S single cluster domain K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 454.0
TLS3_k127_3317737_1 7TM-HD extracellular K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 392.0
TLS3_k127_3317737_2 Yqey-like protein K09117 - - 0.000000000000000000000000000001627 126.0
TLS3_k127_3317737_3 Ribosomal protein S21 K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000006333 83.0
TLS3_k127_3317737_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00004824 51.0
TLS3_k127_334726_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 2.965e-222 720.0
TLS3_k127_334726_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 382.0
TLS3_k127_334726_2 cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 370.0
TLS3_k127_334726_3 PFAM Glucose Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 361.0
TLS3_k127_334726_4 Elongation factor G C-terminus K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 317.0
TLS3_k127_334726_5 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 314.0
TLS3_k127_334726_6 Lysyl oxidase - - - 0.0000000000000000003127 101.0
TLS3_k127_334726_7 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000005481 87.0
TLS3_k127_334726_8 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K01227 - 3.2.1.96 0.00000001082 68.0
TLS3_k127_3350621_0 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 409.0
TLS3_k127_3350621_1 PFAM ABC transporter related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 303.0
TLS3_k127_3350621_2 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001145 289.0
TLS3_k127_3350621_3 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001644 280.0
TLS3_k127_3350621_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000006905 158.0
TLS3_k127_3350621_5 PFAM Protein kinase domain K02486 - 2.7.13.3 0.0000000000000000000000000000296 133.0
TLS3_k127_3354469_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 472.0
TLS3_k127_3354469_1 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000001287 199.0
TLS3_k127_336894_0 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000001068 240.0
TLS3_k127_336894_1 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000001732 124.0
TLS3_k127_336894_2 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.0000000000000000000000000005717 119.0
TLS3_k127_3398_0 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0 1112.0
TLS3_k127_3398_1 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.000000000000000000000000000000000000000000000133 172.0
TLS3_k127_3431376_0 Sortase and related acyltransferases K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000571 170.0
TLS3_k127_3431376_1 response to heat K03668 - - 0.00000000000000000000000001459 119.0
TLS3_k127_3431376_2 Family of unknown function (DUF5317) - - - 0.00000000000000000138 94.0
TLS3_k127_3431376_3 Belongs to the HpcH HpaI aldolase family K01630,K02510,K12660 - 4.1.2.20,4.1.2.52,4.1.2.53 0.0000000000005036 74.0
TLS3_k127_3431376_4 Prolyl oligopeptidase family - - - 0.0000000000006471 73.0
TLS3_k127_3431376_6 Uncharacterized ACR, COG1430 K09005 - - 0.0000004963 58.0
TLS3_k127_3432589_0 Predicted membrane protein (DUF2207) - - - 0.0004481 53.0
TLS3_k127_3438549_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 388.0
TLS3_k127_3438549_1 HpcH/HpaI aldolase/citrate lyase family - - - 0.000000000000000000000000000000000000000000000000000000001107 212.0
TLS3_k127_3438549_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000006303 87.0
TLS3_k127_3438549_3 Sortase and related acyltransferases K03823 - 2.3.1.183 0.000000000003587 68.0
TLS3_k127_3438549_4 EamA-like transporter family - - - 0.0000000001517 72.0
TLS3_k127_3447144_0 Uridine phosphorylase K00757 - 2.4.2.3 0.000000000000000000000000000000000000000000000000000000000000000000006251 245.0
TLS3_k127_3447144_1 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0000000000000000000000000000000000472 146.0
TLS3_k127_3447144_2 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.0002295 55.0
TLS3_k127_3452864_0 Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 578.0
TLS3_k127_3452864_1 triphosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004471 282.0
TLS3_k127_3452864_2 amidohydrolase - - - 0.000000000000000000000000000000000000000000003725 181.0
TLS3_k127_3452864_3 Sigma-70, region 4 K03088 - - 0.000000000000000000008206 101.0
TLS3_k127_3452864_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000008394 102.0
TLS3_k127_3452864_6 Amidohydrolase family - - - 0.0001718 54.0
TLS3_k127_3455439_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K18983 - 5.5.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 410.0
TLS3_k127_3455439_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000005552 138.0
TLS3_k127_3455439_2 gluconolactonase activity K01053,K02352 - 3.1.1.17 0.0002743 47.0
TLS3_k127_3468610_0 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627,K00658,K09699 - 2.3.1.12,2.3.1.168,2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 347.0
TLS3_k127_3468610_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006913 231.0
TLS3_k127_3468610_2 NmrA-like family K00091 - 1.1.1.219 0.0000000000000000000000000000000000000001239 161.0
TLS3_k127_3468610_3 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000000000003717 84.0
TLS3_k127_3468610_4 ATP:ADP antiporter activity K15762 - - 0.000000007608 70.0
TLS3_k127_3476188_0 Among the AAA ATPases, the YifB protease family belongs to the Helix 2 insert clade K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000985 409.0
TLS3_k127_3476188_1 PFAM response regulator receiver K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009226 259.0
TLS3_k127_3476188_2 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000006502 111.0
TLS3_k127_3476188_3 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000008409 101.0
TLS3_k127_3477329_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 555.0
TLS3_k127_3477329_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 364.0
TLS3_k127_3477329_2 IMP dehydrogenase GMP reductase K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000005407 207.0
TLS3_k127_3477329_3 Bacterial-like globin K06886 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000002295 157.0
TLS3_k127_3477329_4 F420H(2)-dependent quinone reductase - - - 0.000006339 56.0
TLS3_k127_3493948_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003697 272.0
TLS3_k127_3493948_1 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000002809 246.0
TLS3_k127_3493948_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000001026 231.0
TLS3_k127_3493948_3 Protein of unknown function (DUF1810) - - - 0.0000000000000000000000000000000000000000003484 166.0
TLS3_k127_3493948_4 ABC-2 family transporter protein K01992 - - 0.0000001234 56.0
TLS3_k127_3511381_0 Trypsin-like serine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 325.0
TLS3_k127_3511381_1 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005147 299.0
TLS3_k127_3511381_2 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004588 255.0
TLS3_k127_3511381_3 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000005752 229.0
TLS3_k127_3511381_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000603 195.0
TLS3_k127_3511381_5 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0000000000000000000000000000006959 139.0
TLS3_k127_3511381_6 - - - - 0.00000001337 64.0
TLS3_k127_3539516_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001444 222.0
TLS3_k127_3539516_1 membrane - - - 0.000000000000000000000000000000000000000000000000000000000393 211.0
TLS3_k127_3539516_2 - - - - 0.0000000000000000000000000000000000000000000000008749 183.0
TLS3_k127_3539516_3 PAS fold - - - 0.000000000000000000000000000000000000003517 158.0
TLS3_k127_3539516_4 transcriptional - - - 0.000000000000000000000000000000000316 136.0
TLS3_k127_3539516_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000006621 115.0
TLS3_k127_3539516_6 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000003681 85.0
TLS3_k127_3585834_0 PFAM extracellular solute-binding protein family 1 K10232 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 471.0
TLS3_k127_3585834_1 PFAM binding-protein-dependent transport systems inner membrane component K10234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006953 378.0
TLS3_k127_3585834_2 Binding-protein-dependent transport system inner membrane component K10233 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 325.0
TLS3_k127_3585834_3 PFAM glycoside hydrolase, family 3 domain protein K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 330.0
TLS3_k127_3585834_4 PFAM ROK family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005942 252.0
TLS3_k127_3585834_5 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000002006 222.0
TLS3_k127_3585834_6 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.0000000000000000000000000000000000000003112 164.0
TLS3_k127_3598004_0 Protein of unknown function (DUF3131) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 617.0
TLS3_k127_3598004_1 Glycosyl hydrolases family 39 K01198 - 3.2.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 396.0
TLS3_k127_3598004_2 Extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 383.0
TLS3_k127_3598004_3 PFAM binding-protein-dependent transport systems inner membrane component K02025,K10118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 356.0
TLS3_k127_3598004_4 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 331.0
TLS3_k127_3608824_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 8.991e-210 669.0
TLS3_k127_3608824_1 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 444.0
TLS3_k127_3608824_10 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000001294 197.0
TLS3_k127_3608824_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006687 424.0
TLS3_k127_3608824_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 423.0
TLS3_k127_3608824_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K12369 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 406.0
TLS3_k127_3608824_5 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 398.0
TLS3_k127_3608824_6 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 365.0
TLS3_k127_3608824_7 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 351.0
TLS3_k127_3608824_8 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000001393 243.0
TLS3_k127_3608824_9 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000002348 237.0
TLS3_k127_3612184_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 325.0
TLS3_k127_3612184_1 Two component transcriptional regulator, winged helix family K07667,K07668 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009691 248.0
TLS3_k127_3612184_2 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000002049 177.0
TLS3_k127_3612184_3 - - - - 0.00000000000000000000000000001618 124.0
TLS3_k127_3612184_4 Tellurite resistance protein TerB - - - 0.000000000000000001103 95.0
TLS3_k127_3612184_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.0000000008232 67.0
TLS3_k127_361377_0 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 316.0
TLS3_k127_361377_1 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000002431 260.0
TLS3_k127_361377_2 F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000004206 190.0
TLS3_k127_361377_3 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000005365 164.0
TLS3_k127_361377_4 PFAM EAL domain - - - 0.000000000000000000000000000000000001869 153.0
TLS3_k127_361377_5 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000389 137.0
TLS3_k127_361377_6 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.000000000000000000000000001486 120.0
TLS3_k127_361377_7 pyridoxamine 5'-phosphate K07005 - - 0.0000000000000000000000002839 111.0
TLS3_k127_3644178_0 mandelate racemase muconate lactonizing K18983 - 5.5.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 457.0
TLS3_k127_3644178_1 transferase K07749,K18702 - 2.8.3.16,2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 415.0
TLS3_k127_3644178_2 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008233 419.0
TLS3_k127_3644178_3 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000001081 249.0
TLS3_k127_3644178_4 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000001068 192.0
TLS3_k127_3644178_5 vancomycin resistance protein - - - 0.0000000000000000000000000000000000000000000001262 190.0
TLS3_k127_3644178_6 gluconolactonase activity K01053,K02352 - 3.1.1.17 0.0000000000000000000000000000000000000001875 154.0
TLS3_k127_3644178_7 ABC-type sugar transport system periplasmic component K10439,K21429 - - 0.00000000000000000000000000002718 131.0
TLS3_k127_3644178_8 PFAM single-stranded nucleic acid binding R3H domain protein K06346 - - 0.0000000000000000000001517 99.0
TLS3_k127_364526_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000005744 233.0
TLS3_k127_364526_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000405 182.0
TLS3_k127_364526_2 Protein of unknown function (DUF1290) - - - 0.00000000000000000000000000001147 121.0
TLS3_k127_364526_3 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - - - 0.0001601 48.0
TLS3_k127_3650528_0 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 425.0
TLS3_k127_3650528_1 PFAM Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 379.0
TLS3_k127_3650528_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 327.0
TLS3_k127_3650528_3 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006029 282.0
TLS3_k127_3650528_4 Zn peptidase - - - 0.000000000000000000000000000000000000000000003057 181.0
TLS3_k127_3650528_5 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000003397 164.0
TLS3_k127_3656686_0 Peptidase S15 K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 417.0
TLS3_k127_3656686_1 NUDIX domain - - - 0.00000000000000000000000000000000000000000003439 179.0
TLS3_k127_3656686_2 Phenazine biosynthesis-like protein - - - 0.0000000000000000000000000001119 122.0
TLS3_k127_3660686_0 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 352.0
TLS3_k127_3660686_1 Belongs to the glutaminase family K01425 - 3.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001531 260.0
TLS3_k127_3660686_2 sequence-specific DNA binding K00567,K13529,K15051 - 2.1.1.63,3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000001106 243.0
TLS3_k127_3660686_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000008502 242.0
TLS3_k127_3660686_4 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000001489 153.0
TLS3_k127_3660686_5 Putative methyltransferase - - - 0.0000000000000000001308 102.0
TLS3_k127_3660686_6 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000004191 71.0
TLS3_k127_3660686_7 PFAM GCN5-related N-acetyltransferase - - - 0.000004127 58.0
TLS3_k127_3661960_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.752e-265 826.0
TLS3_k127_3661960_1 PFAM Phenylalanine and histidine ammonia-lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000008184 266.0
TLS3_k127_3677808_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 307.0
TLS3_k127_3677808_1 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000275 210.0
TLS3_k127_3677808_2 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000002458 80.0
TLS3_k127_3679676_0 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 509.0
TLS3_k127_3679676_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 351.0
TLS3_k127_3679676_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001393 282.0
TLS3_k127_3679676_3 Transcriptional regulator sugar kinase K00845,K00886 - 2.7.1.2,2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000004455 256.0
TLS3_k127_3679676_4 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000009219 213.0
TLS3_k127_3679676_5 Ankyrin repeat - - - 0.0000000000000000000000000000000000000002308 160.0
TLS3_k127_3679676_6 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000001992 98.0
TLS3_k127_3679676_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000006715 79.0
TLS3_k127_3679676_8 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000001125 71.0
TLS3_k127_3692939_0 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 477.0
TLS3_k127_3692939_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 301.0
TLS3_k127_3726347_0 FAD dependent oxidoreductase central domain - - - 3.393e-251 817.0
TLS3_k127_3726347_1 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 399.0
TLS3_k127_3726347_2 Trehalose utilization protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 370.0
TLS3_k127_3741987_0 Acetolactate synthase K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 383.0
TLS3_k127_3741987_1 Mur ligase family, catalytic domain K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000001202 276.0
TLS3_k127_3741987_2 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000001912 185.0
TLS3_k127_3741987_3 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000002195 149.0
TLS3_k127_3741987_4 Protein of unknown function (DUF952) K09705 - - 0.0000000000000000000003512 100.0
TLS3_k127_3741987_5 SnoaL-like domain - - - 0.00000000000002925 81.0
TLS3_k127_3741987_6 Domain of unknown function (DUF4115) - - - 0.0006535 49.0
TLS3_k127_3755836_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000002056 267.0
TLS3_k127_3755836_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000005714 254.0
TLS3_k127_3755836_2 Tetrahydrodipicolinate N-succinyltransferase N-terminal K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000008064 244.0
TLS3_k127_3755836_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000001904 124.0
TLS3_k127_3755836_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000008648 84.0
TLS3_k127_3755836_5 PFAM peptidase - - - 0.000000003873 68.0
TLS3_k127_3769894_0 Amidinotransferase K01478 - 3.5.3.6 1.451e-201 642.0
TLS3_k127_3769894_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 532.0
TLS3_k127_3769894_2 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009661 432.0
TLS3_k127_3769894_3 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009873 360.0
TLS3_k127_3769894_4 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001333 265.0
TLS3_k127_3769894_5 slime layer polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000001662 243.0
TLS3_k127_3769894_6 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000002016 190.0
TLS3_k127_3769894_8 - - - - 0.00007549 48.0
TLS3_k127_37716_0 Cys/Met metabolism PLP-dependent enzyme K11325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001475 291.0
TLS3_k127_37716_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000006331 98.0
TLS3_k127_377962_0 Transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 357.0
TLS3_k127_377962_1 ribosylpyrimidine nucleosidase activity K01239,K01250 - 3.2.2.1 0.0000000000000000000000000000009308 138.0
TLS3_k127_377962_2 SnoaL-like polyketide cyclase K15945 - - 0.0000000000000000000001206 98.0
TLS3_k127_379638_0 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 567.0
TLS3_k127_379638_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 325.0
TLS3_k127_379638_2 Phosphotriesterase family K07048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 295.0
TLS3_k127_379638_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 294.0
TLS3_k127_379638_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001291 282.0
TLS3_k127_379638_5 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000002103 207.0
TLS3_k127_379638_6 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000002639 192.0
TLS3_k127_379638_7 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000006714 170.0
TLS3_k127_379638_8 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000001567 163.0
TLS3_k127_379638_9 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000008716 171.0
TLS3_k127_3797008_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 538.0
TLS3_k127_3797008_1 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001801 282.0
TLS3_k127_3797008_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000001094 163.0
TLS3_k127_3801017_0 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 499.0
TLS3_k127_3801017_1 PFAM Cys Met metabolism K01739 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 371.0
TLS3_k127_3801017_2 Belongs to the MenA family. Type 1 subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 317.0
TLS3_k127_3801017_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000002248 205.0
TLS3_k127_3801017_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000002634 129.0
TLS3_k127_3801017_5 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000007601 104.0
TLS3_k127_3801017_6 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000001736 75.0
TLS3_k127_3801017_7 An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor - - - 0.000002466 59.0
TLS3_k127_3801017_8 VIT family - - - 0.0001242 44.0
TLS3_k127_3825335_0 PFAM carbohydrate kinase K00854 - 2.7.1.17 2.064e-198 633.0
TLS3_k127_3825335_1 Belongs to the binding-protein-dependent transport system permease family K10544 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 434.0
TLS3_k127_3825335_2 ATPases associated with a variety of cellular activities K10545 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 359.0
TLS3_k127_3825335_3 Xylose isomerase-like K01805 - 5.3.1.5 0.0000000000000000001167 90.0
TLS3_k127_3850321_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 2.039e-244 769.0
TLS3_k127_3850321_2 Metal-dependent hydrolase K07043 - - 0.0002615 48.0
TLS3_k127_3869642_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 353.0
TLS3_k127_3869642_1 Cytochrome b(N-terminal)/b6/petB - - - 0.000000000000000000000000001301 120.0
TLS3_k127_3907006_0 PFAM alpha amylase, catalytic K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 542.0
TLS3_k127_3907006_1 Alpha-amylase domain K01176 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 488.0
TLS3_k127_3914790_0 Carbamoyl-phosphate synthetase large chain domain protein K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006146 494.0
TLS3_k127_3914790_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 444.0
TLS3_k127_3914790_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 360.0
TLS3_k127_3914790_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 308.0
TLS3_k127_3914790_4 KR domain K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 288.0
TLS3_k127_3914790_5 FabA-like domain K02372 - 4.2.1.59 0.000000000000000000000000000000000000000733 161.0
TLS3_k127_3914790_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000001514 129.0
TLS3_k127_3914790_7 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K00627,K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.3.1.12 0.000000000000000002775 100.0
TLS3_k127_3914790_8 GAF domain - - - 0.0000000003325 70.0
TLS3_k127_3917699_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1146.0
TLS3_k127_3917699_1 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 319.0
TLS3_k127_3917699_2 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000002672 221.0
TLS3_k127_3917699_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000002559 201.0
TLS3_k127_3927179_0 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007944 361.0
TLS3_k127_3927179_1 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000005338 177.0
TLS3_k127_3927179_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00003024 47.0
TLS3_k127_3960851_0 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 437.0
TLS3_k127_3960851_1 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 320.0
TLS3_k127_3960851_2 PFAM dehydrogenase, E1 component K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 314.0
TLS3_k127_3960851_3 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 311.0
TLS3_k127_3960851_4 methionine synthase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000004287 217.0
TLS3_k127_3960851_5 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K18983 - 5.5.1.27 0.000000000000000000000000000000000000000000000000000003752 203.0
TLS3_k127_3978357_0 Glycosyl transferases group 1 K19424 - - 0.000000000000000000000000000000000000000000000000002908 197.0
TLS3_k127_3978357_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000006148 114.0
TLS3_k127_3986808_0 cytochrome P-450 K00493 - 1.14.14.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 378.0
TLS3_k127_3986808_1 NAD synthase K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000109 290.0
TLS3_k127_3986808_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000001634 218.0
TLS3_k127_3986808_3 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000004863 193.0
TLS3_k127_3986808_4 Potential Queuosine, Q, salvage protein family - - - 0.000000000000000000000000000000000000000176 164.0
TLS3_k127_3986808_5 IstB-like ATP binding N-terminal - - - 0.00006085 53.0
TLS3_k127_3999035_0 PFAM sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007843 478.0
TLS3_k127_3999035_1 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 475.0
TLS3_k127_3999035_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 446.0
TLS3_k127_3999035_3 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 466.0
TLS3_k127_3999035_4 PFAM binding-protein-dependent transport systems inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 340.0
TLS3_k127_3999035_5 PFAM binding-protein-dependent transport systems inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009968 277.0
TLS3_k127_3999035_6 glycine betaine transport K02002 - - 0.000000000000000000000000000000000000000000000000006893 184.0
TLS3_k127_3999035_7 Haloacid dehalogenase-like hydrolase family protein. Source PGD - - - 0.00000000000000000000000000000000000000000000006018 182.0
TLS3_k127_3999035_8 Belongs to the BI1 family K06890,K19416 - - 0.000000000000000000000000000000000000000000001222 175.0
TLS3_k127_3999035_9 Pfam:DUF59 - - - 0.00000000004162 69.0
TLS3_k127_4020788_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 347.0
TLS3_k127_4020788_1 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000001009 168.0
TLS3_k127_4070441_0 mandelate racemase muconate lactonizing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 325.0
TLS3_k127_4070441_1 KR domain K18009 - 1.1.1.304,1.1.1.76 0.000000000000000000000000000000000000003583 156.0
TLS3_k127_4083995_0 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 377.0
TLS3_k127_4083995_1 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009981 289.0
TLS3_k127_4083995_2 HD domain - - - 0.0000000000000000000000000001681 123.0
TLS3_k127_4083995_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596,K00823 - 2.6.1.19,4.1.1.64 0.00000000000000000000000466 105.0
TLS3_k127_4126592_0 Bacterial extracellular solute-binding protein K10232 - - 2.924e-214 673.0
TLS3_k127_4126592_1 Binding-protein-dependent transport system inner membrane component K10233 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 496.0
TLS3_k127_4126592_2 PFAM binding-protein-dependent transport systems inner membrane component K10234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 477.0
TLS3_k127_4133585_0 Type II/IV secretion system protein K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 578.0
TLS3_k127_4133585_1 PFAM type II secretion system protein K12510 - - 0.00008761 51.0
TLS3_k127_4142689_0 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000007209 220.0
TLS3_k127_4142689_1 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000004291 148.0
TLS3_k127_4142689_2 TIGRFAM endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000174 93.0
TLS3_k127_4142689_3 Alpha/beta hydrolase family K07020 - - 0.000000000000000000024 105.0
TLS3_k127_4142689_4 N-acetylmuramoyl-L-alanine amidase - - - 0.0000000000000000001183 100.0
TLS3_k127_4162283_0 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 371.0
TLS3_k127_4162283_2 Cupin domain - - - 0.000000000000000000000000162 112.0
TLS3_k127_4164595_0 Daunorubicin resistance abc transporter atpase subunit K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 391.0
TLS3_k127_4164595_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000003467 253.0
TLS3_k127_4171476_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 392.0
TLS3_k127_4171476_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000006931 186.0
TLS3_k127_4171476_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.0000000007658 61.0
TLS3_k127_4177164_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 3.844e-243 791.0
TLS3_k127_4177164_1 Recombination factor protein RarA K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000002402 227.0
TLS3_k127_4177164_2 Peptidase dimerisation domain K21613 - - 0.0000000000000000000000000000000000000000000000000000000000002674 224.0
TLS3_k127_4177164_3 nuclear chromosome segregation - - - 0.0000000000000000000000418 106.0
TLS3_k127_4188184_0 helix_turn_helix gluconate operon transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000008958 244.0
TLS3_k127_4188184_1 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000001143 139.0
TLS3_k127_4229353_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009241 274.0
TLS3_k127_4229353_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000001312 212.0
TLS3_k127_4229353_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000001836 168.0
TLS3_k127_4229353_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000002813 112.0
TLS3_k127_4234893_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 314.0
TLS3_k127_4234893_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000001436 197.0
TLS3_k127_4234893_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000002303 96.0
TLS3_k127_4237903_0 AI-2E family transporter - - - 0.00000000000000000000000000001098 137.0
TLS3_k127_4237903_1 permease - - - 0.00000000000000003243 96.0
TLS3_k127_4248197_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 343.0
TLS3_k127_4248197_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003054 291.0
TLS3_k127_431276_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 306.0
TLS3_k127_431276_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006651 281.0
TLS3_k127_431276_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000004889 187.0
TLS3_k127_431276_3 carboxylic ester hydrolase activity - - - 0.00000000002683 67.0
TLS3_k127_4314374_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 315.0
TLS3_k127_4314374_1 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000006967 155.0
TLS3_k127_4314374_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000001461 121.0
TLS3_k127_4316537_0 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 303.0
TLS3_k127_4316537_1 to chymotrypsin. May be specialized for the degradation of chitin- linked proteins. Has a primary specificity for large aliphatic or aromatic amino acids K18546 - - 0.00000001015 66.0
TLS3_k127_4331155_0 Male sterility protein K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 376.0
TLS3_k127_4331155_1 PFAM Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 314.0
TLS3_k127_4331155_2 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000009245 262.0
TLS3_k127_4331155_3 UDP-N-acetylglucosamine 2-epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000001297 232.0
TLS3_k127_4331155_4 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000001671 134.0
TLS3_k127_4337004_0 Acetylornithine deacetylase K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 329.0
TLS3_k127_4337004_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000002381 252.0
TLS3_k127_4337004_2 Amidinotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000001239 244.0
TLS3_k127_4337004_3 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000007328 168.0
TLS3_k127_4337004_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000001341 150.0
TLS3_k127_4337004_5 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000001356 143.0
TLS3_k127_4337004_6 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.0000000000000000000000000000001917 138.0
TLS3_k127_4337004_7 Cupin domain - - - 0.00000000000000000000000000006685 119.0
TLS3_k127_4337004_8 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.00000000000001003 77.0
TLS3_k127_4337004_9 FAD dependent oxidoreductase - - - 0.0003206 53.0
TLS3_k127_4354309_0 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 340.0
TLS3_k127_4354309_1 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.0000000000000000000000000002399 126.0
TLS3_k127_4385615_0 Putative glutamine amidotransferase K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 472.0
TLS3_k127_4385615_1 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 378.0
TLS3_k127_4385615_2 PFAM regulatory protein, ArsR - - - 0.00000000000000000000000000004714 127.0
TLS3_k127_4385615_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0002339 55.0
TLS3_k127_4386959_0 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 357.0
TLS3_k127_4386959_1 PFAM DSBA oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 290.0
TLS3_k127_4386959_2 PFAM FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000004967 155.0
TLS3_k127_43881_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 307.0
TLS3_k127_43881_1 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 325.0
TLS3_k127_43881_2 TIGRFAM phosphoenolpyruvate phosphomutase K01841 - 5.4.2.9 0.000000000000000000000000000000000000000000000000000000000000006902 232.0
TLS3_k127_43881_3 - - - - 0.000000000000000000000000000000000000000000000000000000000002865 224.0
TLS3_k127_43881_4 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0000000000000000000000006401 113.0
TLS3_k127_43881_5 Aminoglycoside phosphotransferase - - - 0.00000000000000000001818 106.0
TLS3_k127_4414254_0 Belongs to the malate synthase family K01638 - 2.3.3.9 3.959e-217 691.0
TLS3_k127_4414254_1 xanthine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 623.0
TLS3_k127_4414254_2 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 520.0
TLS3_k127_4414254_3 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009899 275.0
TLS3_k127_4414254_4 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin K00365 - 1.7.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001873 273.0
TLS3_k127_4414254_5 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000002541 207.0
TLS3_k127_4414254_6 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.000000000000000000000000000000000000000000000001193 180.0
TLS3_k127_4414254_7 transcriptional regulator - - - 0.0000000000000000000000000000000000004616 153.0
TLS3_k127_4414254_8 OHCU decarboxylase - - - 0.0000000000000005152 85.0
TLS3_k127_4414254_9 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0006648 44.0
TLS3_k127_4444818_0 transferase activity, transferring glycosyl groups K00786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000131 251.0
TLS3_k127_4444818_1 ATP-grasp - - - 0.000000000000000000000000000000000000000006661 165.0
TLS3_k127_4452697_0 Belongs to the GcvT family K00605 - 2.1.2.10 9.039e-209 653.0
TLS3_k127_4452697_1 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 525.0
TLS3_k127_4452697_2 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 519.0
TLS3_k127_4452697_3 - K22344 - 1.14.13.238 0.0000000000000000000000000000000000000000000000000000006133 207.0
TLS3_k127_4452697_4 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.1.2.10 0.0005076 46.0
TLS3_k127_445726_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 2.626e-237 758.0
TLS3_k127_445726_1 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000002573 151.0
TLS3_k127_445726_2 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000001918 134.0
TLS3_k127_445726_3 - - - - 0.000000000000000000000001058 111.0
TLS3_k127_445726_4 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 0.00000000000000000000000797 102.0
TLS3_k127_4457296_0 Metallopeptidase family M24 - - - 4.392e-194 612.0
TLS3_k127_4457296_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000039 104.0
TLS3_k127_4461374_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004083 278.0
TLS3_k127_4461374_1 MazG nucleotide pyrophosphohydrolase domain K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000335 247.0
TLS3_k127_4461374_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000007946 173.0
TLS3_k127_4461374_3 Cell envelope-related transcriptional attenuator domain - - - 0.000000000000000000000000000003829 136.0
TLS3_k127_4461374_4 peptidyl-prolyl isomerase K03771 - 5.2.1.8 0.00000003296 64.0
TLS3_k127_4469693_0 Transcriptional regulator PadR-like family K10947 - - 0.000000000000000000000000000000000000394 152.0
TLS3_k127_4469693_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000007855 131.0
TLS3_k127_4469693_2 - - - - 0.000000000000000000000000000001776 134.0
TLS3_k127_4469693_3 Cupin domain - - - 0.00000000000000000000000000007101 123.0
TLS3_k127_4469693_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000555 109.0
TLS3_k127_4469693_5 WYL domain - - - 0.00003934 46.0
TLS3_k127_4503893_0 Zn-dependent dipeptidase, microsomal dipeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 394.0
TLS3_k127_4503893_1 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001924 263.0
TLS3_k127_4503893_2 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.000000000000000000000000000000000000000002698 162.0
TLS3_k127_4509742_0 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 GO:0000287,GO:0003674,GO:0003824,GO:0004016,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016020,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0023052,GO:0030145,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052652,GO:0055086,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 357.0
TLS3_k127_4509742_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000001301 127.0
TLS3_k127_45174_0 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000003786 238.0
TLS3_k127_45174_1 MFS transporter K03449 - - 0.00000000000000000000000000000000000000000000000000003165 205.0
TLS3_k127_4556262_0 tRNA (guanine-N7-)-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 433.0
TLS3_k127_4556262_1 Glycosyltransferases involved in cell wall biogenesis-like protein - - - 0.00000000000000000000000000000000000008684 152.0
TLS3_k127_4556262_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000001208 145.0
TLS3_k127_4556262_3 Acetyltransferase (GNAT) domain - - - 0.00000000001492 74.0
TLS3_k127_4556262_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000004425 61.0
TLS3_k127_4556262_5 Glycosyltransferase family 87 - - - 0.00000617 59.0
TLS3_k127_4560935_0 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 385.0
TLS3_k127_4560935_1 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000004335 202.0
TLS3_k127_4560935_2 Diacylglycerol kinase K19302 - 3.6.1.27 0.00000000000000000000157 109.0
TLS3_k127_4560935_3 pilus organization - - - 0.00000000006658 69.0
TLS3_k127_4560935_5 - - - - 0.0001681 52.0
TLS3_k127_4589977_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00122,K00335 - 1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008488 553.0
TLS3_k127_4589977_1 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007396 415.0
TLS3_k127_4589977_2 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000004204 117.0
TLS3_k127_4591887_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 486.0
TLS3_k127_4591887_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009822 323.0
TLS3_k127_4591887_10 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000002268 114.0
TLS3_k127_4591887_11 Belongs to the UPF0109 family K06960 - - 0.0000000000000000001061 90.0
TLS3_k127_4591887_12 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.0000000000000005714 88.0
TLS3_k127_4591887_13 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000009785 66.0
TLS3_k127_4591887_14 Uncharacterised protein family UPF0102 K07460 - - 0.00000004834 61.0
TLS3_k127_4591887_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 301.0
TLS3_k127_4591887_3 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000001611 259.0
TLS3_k127_4591887_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000009233 259.0
TLS3_k127_4591887_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000001649 242.0
TLS3_k127_4591887_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000006136 225.0
TLS3_k127_4591887_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000008282 210.0
TLS3_k127_4591887_8 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000008748 150.0
TLS3_k127_4591887_9 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000001797 139.0
TLS3_k127_4653937_0 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 434.0
TLS3_k127_4653937_1 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 409.0
TLS3_k127_4653937_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006238 265.0
TLS3_k127_4653937_3 Branched-chain amino acid transport system / permease component K10440,K17206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000555 251.0
TLS3_k127_4653937_4 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000007243 238.0
TLS3_k127_4653937_5 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000001675 228.0
TLS3_k127_4653937_6 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000000000000000000000505 203.0
TLS3_k127_4653937_7 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000001207 198.0
TLS3_k127_4653937_8 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000004641 164.0
TLS3_k127_4653937_9 - - - - 0.00000000005635 65.0
TLS3_k127_4672008_0 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002028 280.0
TLS3_k127_4672008_1 metallopeptidase activity K03568 - - 0.00000000000000000000000000000000000000000000005876 171.0
TLS3_k127_4748329_0 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003557 237.0
TLS3_k127_4748329_1 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000003786 79.0
TLS3_k127_4748329_2 Cupredoxin-like domain - - - 0.0006352 52.0
TLS3_k127_475879_0 DNA methylase K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000002201 211.0
TLS3_k127_475879_1 TPM domain - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000001816 88.0
TLS3_k127_4800050_0 protein involved in exopolysaccharide biosynthesis - - - 7.345e-196 640.0
TLS3_k127_4800050_1 belongs to the thioredoxin family K20543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 562.0
TLS3_k127_4800050_2 Xaa-Pro aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 514.0
TLS3_k127_4800050_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000001116 207.0
TLS3_k127_4813284_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 413.0
TLS3_k127_4813284_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 325.0
TLS3_k127_4813284_10 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000004843 189.0
TLS3_k127_4813284_11 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000915 181.0
TLS3_k127_4813284_12 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000001066 168.0
TLS3_k127_4813284_13 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000002668 142.0
TLS3_k127_4813284_14 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.0000000000000000000000000000000004751 131.0
TLS3_k127_4813284_15 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000005235 143.0
TLS3_k127_4813284_16 ribosomal protein l17 K02879 - - 0.000000000000000000000000000007447 123.0
TLS3_k127_4813284_17 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000004539 78.0
TLS3_k127_4813284_18 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000005159 70.0
TLS3_k127_4813284_19 Ribosomal protein L30p/L7e K02907 - - 0.00000000001655 67.0
TLS3_k127_4813284_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 323.0
TLS3_k127_4813284_20 PFAM Protein kinase domain - - - 0.0005062 51.0
TLS3_k127_4813284_3 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005799 274.0
TLS3_k127_4813284_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002962 258.0
TLS3_k127_4813284_5 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000005866 239.0
TLS3_k127_4813284_6 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000005735 226.0
TLS3_k127_4813284_7 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000875 223.0
TLS3_k127_4813284_8 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000000009684 199.0
TLS3_k127_4813284_9 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000004997 198.0
TLS3_k127_4819393_0 Belongs to the glycosyl hydrolase family 6 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 297.0
TLS3_k127_4819393_1 - - - - 0.0000000000000000000000000001966 127.0
TLS3_k127_4821682_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 6.488e-248 775.0
TLS3_k127_4821682_1 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 317.0
TLS3_k127_4821682_2 Homocysteine S-methyltransferase K00547,K21169 - 2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000001096 277.0
TLS3_k127_4821682_3 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000004923 147.0
TLS3_k127_4821682_5 Histidine kinase-like ATPase domain - - - 0.0000000000002219 75.0
TLS3_k127_4821682_6 STAS domain - - - 0.000000001569 66.0
TLS3_k127_4821682_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000005833 64.0
TLS3_k127_4821682_8 YGGT family - - - 0.000179 51.0
TLS3_k127_4824381_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 391.0
TLS3_k127_4824381_1 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 322.0
TLS3_k127_4824381_10 Serine aminopeptidase, S33 - - - 0.00000000000000000000000002073 120.0
TLS3_k127_4824381_11 ABC-2 family transporter protein - - - 0.000000000000000000000001247 117.0
TLS3_k127_4824381_12 ECF sigma factor K03088 - - 0.0000000000000000001013 96.0
TLS3_k127_4824381_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 295.0
TLS3_k127_4824381_3 Aerotolerance regulator N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 315.0
TLS3_k127_4824381_4 Putative glutamine amidotransferase K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 297.0
TLS3_k127_4824381_5 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001834 252.0
TLS3_k127_4824381_6 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004471 241.0
TLS3_k127_4824381_7 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000005052 251.0
TLS3_k127_4824381_8 COGs COG3367 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000008834 217.0
TLS3_k127_4824381_9 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000003618 176.0
TLS3_k127_4862150_0 FeS assembly protein SufB K09014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 411.0
TLS3_k127_4862150_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 327.0
TLS3_k127_4862150_2 TIGRFAM FeS assembly protein SufD K09015 - - 0.0000000000000000000000000000000000000000000001767 188.0
TLS3_k127_4862150_3 Penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000003089 166.0
TLS3_k127_4862150_4 Rieske 2Fe-2S K05710 - - 0.00000000000006796 80.0
TLS3_k127_4932357_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 338.0
TLS3_k127_4932357_1 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000001051 207.0
TLS3_k127_4932357_2 D-aminopeptidase K16203 - - 0.00000000000000000000000000000000000000000000000000004655 201.0
TLS3_k127_4932357_3 Molybdopterin converting factor subunit K03635,K21142 - 2.8.1.12 0.00000000000000000000000000000000000000000003999 178.0
TLS3_k127_4932357_4 PFAM Conserved TM helix repeat-containing protein - - - 0.0000000000000000000000000000000000000002543 161.0
TLS3_k127_4932357_5 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit K01844 - 5.4.3.3 0.000000000000000000000005226 118.0
TLS3_k127_4932357_6 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000000002004 93.0
TLS3_k127_4933987_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 349.0
TLS3_k127_4933987_1 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000007559 103.0
TLS3_k127_4933987_2 3-oxoadipate enol-lactonase K01055 - 3.1.1.24 0.00000000005044 64.0
TLS3_k127_4943412_0 GMC oxidoreductase - - - 1.26e-241 760.0
TLS3_k127_4943412_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 311.0
TLS3_k127_4943412_2 transmembrane transporter activity K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 299.0
TLS3_k127_4943412_3 Aldehyde dehydrogenase family K00141 - 1.2.1.28 0.00000000000000000000000000000000000000000000000000000000000009155 226.0
TLS3_k127_4943412_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000004997 223.0
TLS3_k127_4943412_5 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000434 175.0
TLS3_k127_4943412_6 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000001464 139.0
TLS3_k127_4943412_7 - - - - 0.000000007755 65.0
TLS3_k127_4952099_0 SMART alpha amylase catalytic sub domain K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008754 461.0
TLS3_k127_4952099_1 ATPase associated with various cellular K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 441.0
TLS3_k127_4952099_10 zinc finger - - - 0.0004698 53.0
TLS3_k127_4952099_2 Cell cycle protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009978 343.0
TLS3_k127_4952099_3 PFAM penicillin-binding protein transpeptidase K05364 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007239 280.0
TLS3_k127_4952099_4 PFAM Bacterial regulatory proteins, lacI family K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004721 267.0
TLS3_k127_4952099_5 ABC transporter substrate-binding protein K10232 - - 0.00000000000000000000000000000000000000000000000000000000001273 220.0
TLS3_k127_4952099_6 PFAM Forkhead-associated protein - - - 0.0000000000000000000000000000000005593 141.0
TLS3_k127_4952099_7 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000532 101.0
TLS3_k127_4952099_8 Virulence factor BrkB K07058 - - 0.000000002079 68.0
TLS3_k127_4952099_9 Regulatory protein, FmdB family - - - 0.00000001133 61.0
TLS3_k127_4982293_0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 454.0
TLS3_k127_4982293_1 Nucleoside 2-deoxyribosyltransferase - - - 0.00000000000000000000000000000002152 131.0
TLS3_k127_4986105_0 Type II/IV secretion system protein K02283 - - 2.472e-198 627.0
TLS3_k127_5015294_0 Trimethylamine methyltransferase (MTTB) - - - 6.238e-214 677.0
TLS3_k127_5015294_1 Belongs to the aldehyde dehydrogenase family K00146,K09472 - 1.2.1.39,1.2.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 608.0
TLS3_k127_5015294_2 Mandelate racemase muconate lactonizing enzyme K18983 - 5.5.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 466.0
TLS3_k127_5015294_3 Belongs to the GcvT family K00315 - 1.5.8.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 396.0
TLS3_k127_5015294_4 Bacterial transcriptional regulator - - - 0.00000000000000000000000000000000001035 149.0
TLS3_k127_5023232_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 365.0
TLS3_k127_5023232_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02033,K12369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006684 352.0
TLS3_k127_5023232_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 346.0
TLS3_k127_5023232_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 353.0
TLS3_k127_5023232_4 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 329.0
TLS3_k127_5023232_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 314.0
TLS3_k127_5023232_6 Phenazine biosynthesis-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000005666 226.0
TLS3_k127_5023232_7 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000017 139.0
TLS3_k127_5023232_8 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000005043 121.0
TLS3_k127_5026573_0 Binding-protein-dependent transport system inner membrane component K02001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 542.0
TLS3_k127_5026573_1 glycine betaine K02000 - 3.6.3.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 486.0
TLS3_k127_5026573_2 glycine betaine transport K02002 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003938 252.0
TLS3_k127_5026573_3 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.0000000000000000000000000000001108 124.0
TLS3_k127_5035325_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 595.0
TLS3_k127_5035325_1 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 449.0
TLS3_k127_5035325_2 transcriptional regulator - - - 0.0000000005256 64.0
TLS3_k127_5054831_0 COG0659 Sulfate permease and related transporters (MFS superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008909 259.0
TLS3_k127_5054831_1 Ion transport protein K10716 - - 0.0000000000000000000000000000000000001098 152.0
TLS3_k127_512280_0 ABC transporter substrate-binding protein K10543 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 314.0
TLS3_k127_512280_1 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 300.0
TLS3_k127_512280_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002535 234.0
TLS3_k127_5173220_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 439.0
TLS3_k127_5173220_1 Fungal trichothecene efflux pump (TRI12) - - - 0.00000000000000000000001378 106.0
TLS3_k127_5173220_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000001258 108.0
TLS3_k127_5173220_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000005132 65.0
TLS3_k127_5200917_0 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 332.0
TLS3_k127_5200917_1 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000000000000000000000000000000000000001555 219.0
TLS3_k127_5200917_2 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000141 181.0
TLS3_k127_5200917_3 Redoxin - - - 0.000000000000000000000000000000000000001517 155.0
TLS3_k127_5200917_4 Required for disulfide bond formation in some proteins K03611 - - 0.00000000000000000000000000006085 122.0
TLS3_k127_5200917_5 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000005418 61.0
TLS3_k127_5214864_0 import. Responsible for energy coupling to the transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 473.0
TLS3_k127_5214864_1 Berberine and berberine like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 440.0
TLS3_k127_5214864_2 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 353.0
TLS3_k127_5214864_3 SIS domain K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000004386 235.0
TLS3_k127_5214864_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000001568 179.0
TLS3_k127_5214864_5 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000001225 146.0
TLS3_k127_5225063_0 Mur ligase middle domain K03802 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 347.0
TLS3_k127_5225063_1 peptidase K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 339.0
TLS3_k127_5225063_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000003628 213.0
TLS3_k127_5225063_3 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000004393 134.0
TLS3_k127_5225063_4 branched-chain amino acid permease (azaleucine resistance) - - - 0.0000000000000000000000000000005022 134.0
TLS3_k127_5230364_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 587.0
TLS3_k127_5230364_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 577.0
TLS3_k127_5230364_10 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000001858 85.0
TLS3_k127_5230364_11 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0005583 51.0
TLS3_k127_5230364_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 427.0
TLS3_k127_5230364_3 Belongs to the glycosyl hydrolase 3 family K01207,K05349 - 3.2.1.21,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 358.0
TLS3_k127_5230364_4 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006595 269.0
TLS3_k127_5230364_5 Sap, sulfolipid-1-addressing protein - - - 0.0000000000000000000000000000000000000000000000312 179.0
TLS3_k127_5230364_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000000000000006905 172.0
TLS3_k127_5230364_7 SMART Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000019 168.0
TLS3_k127_5230364_8 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion K02564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.6 0.0000000000000000000000000000000000000002608 164.0
TLS3_k127_5230364_9 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000002396 126.0
TLS3_k127_5235203_0 Bacterial protein of unknown function (DUF853) K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 373.0
TLS3_k127_5235203_1 Domain of unknown function (DUF4332) - - - 0.0000000000000000000000000000000000004396 145.0
TLS3_k127_5235203_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000001928 117.0
TLS3_k127_5235203_3 chorismate mutase K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.0000000000000000000000143 104.0
TLS3_k127_5242979_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 537.0
TLS3_k127_5242979_1 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000001208 283.0
TLS3_k127_524965_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000935 329.0
TLS3_k127_524965_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 316.0
TLS3_k127_524965_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000007512 192.0
TLS3_k127_5326929_0 ABC 3 transport family K09816,K09819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 346.0
TLS3_k127_5326929_1 ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005264 286.0
TLS3_k127_5326929_10 Phospholipase_D-nuclease N-terminal - - - 0.0000000000339 65.0
TLS3_k127_5326929_2 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006814 267.0
TLS3_k127_5326929_3 Zinc-uptake complex component A periplasmic K02077,K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000001649 235.0
TLS3_k127_5326929_4 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000001 221.0
TLS3_k127_5326929_5 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000008068 196.0
TLS3_k127_5326929_6 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000001574 155.0
TLS3_k127_5326929_7 Transcriptional - - - 0.000000000000000000000000000007873 120.0
TLS3_k127_5326929_8 ABC-type Mn2 Zn2 transport systems permease components - - - 0.00000000000000000000000005867 109.0
TLS3_k127_5326929_9 Belongs to the Fur family K03711 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000004048 67.0
TLS3_k127_5339759_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.73e-235 749.0
TLS3_k127_5339759_1 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 378.0
TLS3_k127_5339759_2 Bacterial DNA topoisomeraes I ATP-binding domain K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 325.0
TLS3_k127_5339759_3 MviN-like protein K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000001437 250.0
TLS3_k127_5339759_4 tyrosine recombinase XerC K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000002291 226.0
TLS3_k127_5339759_5 PFAM Methicillin resistance protein - - - 0.00000000000000000000000000000000000000000000004635 183.0
TLS3_k127_5339759_6 Methicillin resistance protein K05363,K11693 - 2.3.2.10,2.3.2.16 0.000000001822 69.0
TLS3_k127_5346170_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000725 455.0
TLS3_k127_5346170_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 345.0
TLS3_k127_5346170_2 PFAM conserved K07027 - - 0.000000000000000000000000000000000000000000000000000000000000001628 235.0
TLS3_k127_5346170_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000002968 139.0
TLS3_k127_5346170_4 PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000000003587 145.0
TLS3_k127_5346170_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 0.00000000000000000000003287 99.0
TLS3_k127_5387533_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 322.0
TLS3_k127_5387533_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000001539 240.0
TLS3_k127_5387533_2 PFAM Peptidase M23 K21471 - - 0.0000000000000000000000009913 121.0
TLS3_k127_5387533_3 Type IV leader peptidase family K02654 - 3.4.23.43 0.000000000000006101 86.0
TLS3_k127_5391421_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 424.0
TLS3_k127_5391421_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 417.0
TLS3_k127_5391421_2 Queuine tRNA-ribosyltransferase K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 378.0
TLS3_k127_5391421_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000001679 175.0
TLS3_k127_5391421_4 Transcriptional regulator - - - 0.000000000000000000000000000000001627 136.0
TLS3_k127_5391421_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000001071 136.0
TLS3_k127_5391421_6 regulation of RNA biosynthetic process - - - 0.000000000000000000000000000117 119.0
TLS3_k127_5408595_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 434.0
TLS3_k127_5408595_1 PFAM alanine dehydrogenase PNT domain protein K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 420.0
TLS3_k127_5408595_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001941 259.0
TLS3_k127_5408595_3 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000002382 214.0
TLS3_k127_5408595_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000001668 188.0
TLS3_k127_5408595_5 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000001945 176.0
TLS3_k127_5408595_6 NADP transhydrogenase K00324 - 1.6.1.2 0.00000000000000000000000000000002637 132.0
TLS3_k127_5408595_7 DNA-binding protein - - - 0.0000000000000000000001315 104.0
TLS3_k127_5408595_8 - - - - 0.00000000000000000001603 93.0
TLS3_k127_5414408_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.6.3.14 1.972e-212 668.0
TLS3_k127_5414408_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004409 267.0
TLS3_k127_5414408_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 0.00000000000000000000000000000000000000000000003018 173.0
TLS3_k127_5416409_0 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 562.0
TLS3_k127_5416409_1 pathogenesis - - - 0.0004578 51.0
TLS3_k127_5426149_0 PspA/IM30 family K03969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003083 274.0
TLS3_k127_5426149_1 TPM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000161 285.0
TLS3_k127_5426149_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000001033 237.0
TLS3_k127_5426149_3 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.0000000000000000000000000000000283 131.0
TLS3_k127_5426149_4 - - - - 0.00000004351 60.0
TLS3_k127_5440382_0 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 603.0
TLS3_k127_5440382_1 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 552.0
TLS3_k127_5440382_2 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 334.0
TLS3_k127_5440382_3 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.000000000000000000000000000000000000000000000000000000000000000006735 241.0
TLS3_k127_5440382_4 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000001182 229.0
TLS3_k127_5440382_5 Dodecin K09165 - - 0.0000000001415 69.0
TLS3_k127_5451239_0 antibiotic catabolic process K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 422.0
TLS3_k127_5451239_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 401.0
TLS3_k127_5451239_2 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 298.0
TLS3_k127_5517369_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 521.0
TLS3_k127_5517369_1 aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 362.0
TLS3_k127_5517369_2 glyoxalase III activity - - - 0.0000000000000000000000000000000003435 142.0
TLS3_k127_5517369_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 0.00000000000000000624 92.0
TLS3_k127_5517369_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000009264 93.0
TLS3_k127_5541882_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003041 268.0
TLS3_k127_5545916_0 TIGRFAM dihydroxyacetone kinase, DhaK subunit K05878 - 2.7.1.121 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 456.0
TLS3_k127_5545916_1 PEP-utilising enzyme, N-terminal K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 353.0
TLS3_k127_5545916_2 PFAM DoxX family protein K16937 - 1.8.5.2 0.00000000000000000000000000000000000000000000000000000000000000000188 234.0
TLS3_k127_5545916_3 Major intrinsic protein K02440,K06188,K09874 - - 0.00000000000000000000000000000000000000000000000000002961 198.0
TLS3_k127_5545916_4 Dihydroxyacetone kinase K05879 - 2.7.1.121 0.000000000000000000000000000000000000000000001107 176.0
TLS3_k127_5545916_5 Dihydroxyacetone kinase K05879 - 2.7.1.121 0.00000000000000000000000000000000000000002634 162.0
TLS3_k127_5545916_6 phosphoenolpyruvate-glycerone phosphotransferase activity K05881 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324 2.7.1.121 0.0000000000000000000000000001503 122.0
TLS3_k127_5545916_7 SMART PAS domain containing protein - - - 0.00000000000000000000000000163 129.0
TLS3_k127_5545916_8 dead DEAH box helicase K03724 - - 0.000000000000000000001884 98.0
TLS3_k127_5545916_9 PFAM PTS HPr component phosphorylation site K11189 - - 0.000000000004484 74.0
TLS3_k127_5548635_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 335.0
TLS3_k127_5548635_1 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000001608 183.0
TLS3_k127_5555148_0 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000001801 209.0
TLS3_k127_5555148_1 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000001238 192.0
TLS3_k127_5555148_2 PFAM Thiamin pyrophosphokinase, catalytic region K00949 - 2.7.6.2 0.000000000000000000000000000000003163 142.0
TLS3_k127_5555148_3 YbaK prolyl-tRNA synthetase associated - - - 0.00000000000000000000000000000002882 135.0
TLS3_k127_5555148_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.00000000000000000000002334 115.0
TLS3_k127_5567045_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 7.347e-251 794.0
TLS3_k127_5605552_0 aminopeptidase N - - - 0.000000000000000000000000000000000000000000000000002507 206.0
TLS3_k127_5605552_1 aminopeptidase N - - - 0.000000000000000000000501 112.0
TLS3_k127_5609090_0 TrkA-N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 453.0
TLS3_k127_5609090_1 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006417 332.0
TLS3_k127_5609090_10 Catalyzes the synthesis of activated sulfate - - - 0.00000000001631 73.0
TLS3_k127_5609090_11 - - - - 0.0000000003376 70.0
TLS3_k127_5609090_12 PFAM blue (type 1) copper domain protein K00368 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1 0.0003092 49.0
TLS3_k127_5609090_2 Threonyl alanyl tRNA synthetase SAD K07050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008234 259.0
TLS3_k127_5609090_3 Domain of unknown function (DUF4188) - - - 0.00000000000000000000000000000000000000000001627 168.0
TLS3_k127_5609090_4 KR domain - - - 0.000000000000000000000000000000000000002217 158.0
TLS3_k127_5609090_5 Aminoacyl-tRNA editing domain - - - 0.00000000000000000000000000000000000001937 149.0
TLS3_k127_5609090_6 WHG domain - - - 0.00000000000000000000000000000000007756 141.0
TLS3_k127_5609090_7 Belongs to the N(4) N(6)-methyltransferase family - - - 0.00000000000000000000000000000005904 136.0
TLS3_k127_5609090_8 Protein of unknown function (DUF1269) - - - 0.0000000000000000000000002899 115.0
TLS3_k127_5609090_9 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000008019 68.0
TLS3_k127_5621474_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002503 271.0
TLS3_k127_5621474_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000009288 258.0
TLS3_k127_5621474_2 TIGRFAM LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000122 259.0
TLS3_k127_5621474_3 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000001085 190.0
TLS3_k127_5621474_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000001108 161.0
TLS3_k127_5621474_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - 0.00000002037 66.0
TLS3_k127_5637715_0 PFAM Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 366.0
TLS3_k127_5637715_1 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000005449 132.0
TLS3_k127_5637715_2 Transglycosylase - - - 0.0000000000000631 80.0
TLS3_k127_5648809_0 Carboxyl transferase domain K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 3.457e-238 747.0
TLS3_k127_5648809_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 336.0
TLS3_k127_5648809_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000002162 204.0
TLS3_k127_5648809_3 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000343 201.0
TLS3_k127_5648809_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000009484 194.0
TLS3_k127_5648809_5 - K07071 - - 0.00000000000000000000000000000000000000005337 165.0
TLS3_k127_5648809_6 - - - - 0.0000000000000000000000000000000001254 149.0
TLS3_k127_5648809_7 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000002623 132.0
TLS3_k127_5648809_8 Methyltransferase domain - - - 0.00000000000000000000000000000561 130.0
TLS3_k127_5648809_9 methyltransferase K18846 - 2.1.1.180 0.0000000000000528 80.0
TLS3_k127_5656401_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 319.0
TLS3_k127_5656401_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00177 - 1.2.7.1,1.2.7.3 0.000000000000000000000000000000000000000000003926 173.0
TLS3_k127_5669721_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 493.0
TLS3_k127_5669721_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000009041 169.0
TLS3_k127_5669721_2 Regulates arginine biosynthesis genes K03402 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006355,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000001632 109.0
TLS3_k127_5669721_3 Histidine kinase K02484 - 2.7.13.3 0.0000000000000000000000314 115.0
TLS3_k127_5669721_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000008541 77.0
TLS3_k127_56701_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 587.0
TLS3_k127_56701_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 429.0
TLS3_k127_56701_10 Bacterial regulatory proteins, tetR family - - - 0.0009361 51.0
TLS3_k127_56701_2 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 411.0
TLS3_k127_56701_3 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 323.0
TLS3_k127_56701_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002234 277.0
TLS3_k127_56701_5 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003114 260.0
TLS3_k127_56701_6 Major facilitator Superfamily - - - 0.00000000000000000000000000004736 132.0
TLS3_k127_56701_8 Involved in the tonB-independent uptake of proteins K03641 - - 0.000001436 59.0
TLS3_k127_56701_9 Peptidase family S51 - - - 0.00001519 55.0
TLS3_k127_5682398_0 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 299.0
TLS3_k127_5682398_1 Multidrug transporter K03327 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000009887 214.0
TLS3_k127_5682398_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000001242 204.0
TLS3_k127_5682398_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000006005 64.0
TLS3_k127_568758_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.207e-235 744.0
TLS3_k127_568758_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001249 272.0
TLS3_k127_568758_2 Heat shock protein DnaJ domain protein K05516 - - 0.000000000000000000000000000000000000000000000000000000001715 214.0
TLS3_k127_5705294_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1429.0
TLS3_k127_5753495_0 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002373 288.0
TLS3_k127_5753495_1 PFAM Oxidoreductase, molybdopterin binding - - - 0.000000000000000000000000000000000000000000000000000000000002802 214.0
TLS3_k127_5753495_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000001765 124.0
TLS3_k127_5753495_3 Conserved hypothetical protein 698 - - - 0.00004516 48.0
TLS3_k127_575596_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 1.768e-235 741.0
TLS3_k127_575596_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 331.0
TLS3_k127_575596_2 PFAM ABC transporter related K10112 - - 0.00000000000000000000000000000000000000000000002625 185.0
TLS3_k127_5761419_0 Pfam Sulfatase K01130 - 3.1.6.1 1.074e-278 863.0
TLS3_k127_5761419_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 420.0
TLS3_k127_5761419_2 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007853 405.0
TLS3_k127_5761419_3 Threonine/Serine exporter, ThrE - - - 0.0000000000000000000000000000000613 139.0
TLS3_k127_5770916_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000009302 233.0
TLS3_k127_5770916_1 transport systems ATPase components K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000001978 195.0
TLS3_k127_5770916_2 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000003378 76.0
TLS3_k127_5783795_0 Sodium:sulfate symporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 577.0
TLS3_k127_5783795_1 AbgT putative transporter family K12942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 556.0
TLS3_k127_5783795_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 509.0
TLS3_k127_5783795_3 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001125 274.0
TLS3_k127_5783795_4 AI-2E family transporter - - - 0.00000000000000000000000000000000000001971 160.0
TLS3_k127_5783795_5 Phospholipase_D-nuclease N-terminal - - - 0.00000000000000000000001072 114.0
TLS3_k127_5783795_6 - - - - 0.00000000000003296 79.0
TLS3_k127_5784430_0 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 372.0
TLS3_k127_5784430_1 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006392 300.0
TLS3_k127_5784430_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004021 276.0
TLS3_k127_5784430_3 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000009763 173.0
TLS3_k127_5784430_4 Kef-type K transport systems membrane components - - - 0.000000000000000000000000000000000002872 145.0
TLS3_k127_5784430_5 - K03571 - - 0.00000006086 62.0
TLS3_k127_5793400_0 FGGY family of carbohydrate kinases, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 606.0
TLS3_k127_5793400_1 FAD linked oxidases, C-terminal domain K00102,K00803 - 1.1.2.4,2.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 516.0
TLS3_k127_5793400_2 Calcineurin-like phosphoesterase - - - 0.00000000001109 71.0
TLS3_k127_5793400_3 Glycosyltransferase like family 2 - - - 0.000000001065 66.0
TLS3_k127_5793400_4 DNA binding - - - 0.0000000435 66.0
TLS3_k127_579479_0 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 331.0
TLS3_k127_579479_1 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000005283 206.0
TLS3_k127_579479_2 ABC transporter - - - 0.000000000000000000000000000000000000000118 169.0
TLS3_k127_579479_3 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000001322 151.0
TLS3_k127_579479_4 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000008478 137.0
TLS3_k127_579479_5 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000005805 124.0
TLS3_k127_579479_6 - - - - 0.00000000000000000000000000125 119.0
TLS3_k127_579479_7 - - - - 0.00000000000000005029 92.0
TLS3_k127_582205_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 395.0
TLS3_k127_582205_1 Glycosyl transferase 4-like domain K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 301.0
TLS3_k127_582205_10 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000003298 108.0
TLS3_k127_582205_11 Bacterial lipid A biosynthesis acyltransferase K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.265 0.00000000000000000001329 105.0
TLS3_k127_582205_12 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.0008111 54.0
TLS3_k127_582205_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000002138 230.0
TLS3_k127_582205_3 PFAM Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000006322 209.0
TLS3_k127_582205_4 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000004165 152.0
TLS3_k127_582205_5 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000002923 160.0
TLS3_k127_582205_6 Kdo2-lipid A biosynthetic process K02517,K22311 - 2.3.1.241,2.3.1.265 0.00000000000000000000000000000000474 142.0
TLS3_k127_582205_7 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000004184 141.0
TLS3_k127_582205_8 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.00000000000000000000000000003275 138.0
TLS3_k127_582205_9 Glycosyl transferase K00728 - 2.4.1.109 0.000000000000000000000000163 126.0
TLS3_k127_5831082_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 549.0
TLS3_k127_5831082_1 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 423.0
TLS3_k127_5831082_10 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000007918 166.0
TLS3_k127_5831082_11 Calcineurin-like phosphoesterase K03547 - - 0.0000000000000000000000000000002118 139.0
TLS3_k127_5831082_12 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.000000000000000000000000000004425 128.0
TLS3_k127_5831082_13 Probable zinc-ribbon domain - - - 0.000000000000000000000000006919 117.0
TLS3_k127_5831082_14 PNKP adenylyltransferase domain, ligase domain K01090 - 3.1.3.16 0.00000000000000000000000001784 123.0
TLS3_k127_5831082_15 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.000000000000000001759 97.0
TLS3_k127_5831082_16 Metallo-beta-lactamase superfamily - - - 0.00000000000001055 76.0
TLS3_k127_5831082_17 AAA domain - - - 0.000000000003645 80.0
TLS3_k127_5831082_18 Transglycosylase associated protein - - - 0.00000000001468 68.0
TLS3_k127_5831082_19 YCII-related domain K09780 - - 0.000001546 54.0
TLS3_k127_5831082_2 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 426.0
TLS3_k127_5831082_20 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00002591 57.0
TLS3_k127_5831082_3 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007982 347.0
TLS3_k127_5831082_4 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000002696 252.0
TLS3_k127_5831082_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000002109 197.0
TLS3_k127_5831082_6 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000001867 194.0
TLS3_k127_5831082_7 Pfam:DUF2029 - - - 0.0000000000000000000000000000000000000000000000001623 188.0
TLS3_k127_5831082_8 Rieske 2Fe-2S - - - 0.0000000000000000000000000000000000000000000000008851 185.0
TLS3_k127_5831082_9 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000003281 173.0
TLS3_k127_5850426_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 328.0
TLS3_k127_5850426_1 PFAM Lipopolysaccharide kinase (Kdo WaaP) family - - - 0.0000000000000000000000000000000000000000000000000000007816 201.0
TLS3_k127_5850426_2 ABC-2 type transporter K01992 - - 0.00000000000000000000000004965 117.0
TLS3_k127_5880419_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 384.0
TLS3_k127_5880419_1 N-acetylglucosaminylinositol deacetylase activity K18455 - 3.5.1.115 0.00000000000000000000000000000000000000000000000000000000000000000003625 244.0
TLS3_k127_5880419_2 Capsule synthesis protein, CapA K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000002419 231.0
TLS3_k127_5880419_3 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000001375 106.0
TLS3_k127_5880419_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000008077 107.0
TLS3_k127_5880419_5 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000004407 94.0
TLS3_k127_5880419_6 ABC transporter K01990 - - 0.0007961 44.0
TLS3_k127_5884134_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 512.0
TLS3_k127_5884134_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000003778 211.0
TLS3_k127_5884134_2 TrkA-C domain K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000002891 183.0
TLS3_k127_5884134_3 PFAM TrkA-N domain protein K03499 - - 0.000000000000000000000000000000003445 136.0
TLS3_k127_5884134_4 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000001495 136.0
TLS3_k127_5884134_5 Histidine kinase A domain protein - - - 0.00000000000000000000000001487 119.0
TLS3_k127_5884134_6 Universal stress protein family - - - 0.000000000000000000000002101 109.0
TLS3_k127_5903983_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596,K00823 - 2.6.1.19,4.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 526.0
TLS3_k127_5903983_1 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008844 505.0
TLS3_k127_5903983_2 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000001142 187.0
TLS3_k127_5903983_3 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000003793 161.0
TLS3_k127_592527_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003244 245.0
TLS3_k127_592527_1 Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and or methyl galactoside import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000393 204.0
TLS3_k127_592527_2 Aldo/keto reductase family K00064 - 1.1.1.122 0.0000000000000000000000000000000000000000003023 163.0
TLS3_k127_592527_3 Involved in the anomeric conversion of L-rhamnose K03534 - 5.1.3.32 0.000000000003128 78.0
TLS3_k127_5930397_0 Glycosyl hydrolases family 2, TIM barrel domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009937 593.0
TLS3_k127_5930397_1 Belongs to the glycosyl hydrolase 1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 362.0
TLS3_k127_5930397_2 Belongs to the glycosyl hydrolase 43 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 329.0
TLS3_k127_5930397_3 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007207 263.0
TLS3_k127_5930397_4 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003832 264.0
TLS3_k127_5930397_5 beta-glucosidase activity K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000002411 265.0
TLS3_k127_5930397_6 Metallopeptidase family M24 K18829 - - 0.000000000000000000000000000000000000000000000000000000003809 213.0
TLS3_k127_5930397_7 - - - - 0.00000000000000000000000000000002822 128.0
TLS3_k127_5932627_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 3.571e-270 864.0
TLS3_k127_5932627_1 DUF218 domain - - - 0.0000000000000000000000000000000000000005308 159.0
TLS3_k127_5932627_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000001773 74.0
TLS3_k127_594101_0 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000002311 174.0
TLS3_k127_5977529_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 421.0
TLS3_k127_5977529_1 Rieske [2Fe-2S] domain - - - 0.000000000002834 76.0
TLS3_k127_5977529_2 Iron dependent repressor, N-terminal DNA binding domain - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000259 55.0
TLS3_k127_5980079_0 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 381.0
TLS3_k127_5980079_1 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000002674 177.0
TLS3_k127_6006666_0 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.00000000000000000000000000000000000000000000000000000000000006399 224.0
TLS3_k127_6006666_1 Protein of unknown function (DUF3105) - - - 0.00000000000001001 86.0
TLS3_k127_6009847_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009613 352.0
TLS3_k127_6009847_1 recombinase XerD K04763 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006501 282.0
TLS3_k127_6009847_10 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000001068 143.0
TLS3_k127_6009847_11 PFAM membrane-flanked domain - - - 0.000000000000000000000000000000005068 138.0
TLS3_k127_6009847_12 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000001595 103.0
TLS3_k127_6009847_13 mRNA catabolic process - - - 0.000000000006149 73.0
TLS3_k127_6009847_2 rRNA methylase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000643 263.0
TLS3_k127_6009847_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000006193 208.0
TLS3_k127_6009847_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000009318 193.0
TLS3_k127_6009847_5 RNA pseudouridylate synthase K06178,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.0000000000000000000000000000000000000000000005828 183.0
TLS3_k127_6009847_6 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000001446 177.0
TLS3_k127_6009847_7 PFAM peptidase - - - 0.0000000000000000000000000000000000000001133 159.0
TLS3_k127_6009847_8 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000003362 156.0
TLS3_k127_6009847_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000002927 156.0
TLS3_k127_6032818_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1060.0
TLS3_k127_6032818_1 domain, Protein - - - 0.00000000000000000000000001041 117.0
TLS3_k127_6039830_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 369.0
TLS3_k127_6039830_1 PFAM Amidohydrolase 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 334.0
TLS3_k127_6039830_2 SpoU rRNA Methylase family K03437 - - 0.00000000000000000000000000000000000000000000000000000000000000003738 233.0
TLS3_k127_6039830_3 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.000000000000000000000000000000000000000000000000000000006153 218.0
TLS3_k127_6039830_4 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000005167 200.0
TLS3_k127_6039830_5 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000001238 207.0
TLS3_k127_6039830_6 Peptidase MA superfamily - - - 0.00000000000000000000000000000000000004384 161.0
TLS3_k127_6039830_7 Bacterial protein of unknown function (DUF881) - - - 0.00000000000000000000000004792 118.0
TLS3_k127_6039830_8 Bacterial protein of unknown function (DUF951) - - - 0.0000000000000000008653 89.0
TLS3_k127_6039830_9 Bacterial protein of unknown function (DUF881) - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000001236 85.0
TLS3_k127_6042568_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 436.0
TLS3_k127_6042568_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 415.0
TLS3_k127_6042568_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000008269 247.0
TLS3_k127_6042568_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000009776 191.0
TLS3_k127_6042568_4 cheY-homologous receiver domain K11443 - - 0.000000000000000000000000000000000000000000006938 169.0
TLS3_k127_6042568_5 Belongs to the arginase family K01476 - 3.5.3.1 0.00000000000000000000000009364 122.0
TLS3_k127_6049082_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 346.0
TLS3_k127_6049082_1 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 307.0
TLS3_k127_6049082_2 PFAM NMT1 THI5 like domain protein K02051 - - 0.000000000000000000000000000000000000000000000000000000000004724 222.0
TLS3_k127_6049082_3 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000001336 186.0
TLS3_k127_6060312_0 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000005744 233.0
TLS3_k127_6060312_1 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000000000000000000000000000000000000000005906 221.0
TLS3_k127_6060312_2 phosphonoacetaldehyde hydrolase activity K19270 - 3.1.3.23 0.00000000000000000000000000000000000000000000000001958 190.0
TLS3_k127_6060312_3 LemA family K03744 - - 0.00000000000000000000000000001942 132.0
TLS3_k127_6060312_4 phospholipid glycerol acyltransferase - - - 0.000000000000001148 87.0
TLS3_k127_6060312_5 - - - - 0.00000000002599 75.0
TLS3_k127_6072994_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 312.0
TLS3_k127_6072994_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000009019 284.0
TLS3_k127_6072994_2 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001961 255.0
TLS3_k127_6072994_3 ACT domain K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000002787 189.0
TLS3_k127_6072994_4 biotin acetyl-CoA-carboxylase ligase K03524 - 6.3.4.15 0.00000000000000000000000000009443 126.0
TLS3_k127_6072994_5 Sigma-70 region 2 K03088 - - 0.00000000000000000002297 100.0
TLS3_k127_6072994_6 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.00000007594 61.0
TLS3_k127_6081812_0 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 357.0
TLS3_k127_6098644_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000001055 223.0
TLS3_k127_6098644_1 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000000000000000000000006655 186.0
TLS3_k127_6098644_2 PFAM response regulator receiver K02282 - - 0.0000000000000000000000000000000000000000001689 175.0
TLS3_k127_6098644_3 methyltransferase - - - 0.0005285 46.0
TLS3_k127_6141621_0 CBS domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 303.0
TLS3_k127_6141621_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000001765 274.0
TLS3_k127_6141621_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000005114 182.0
TLS3_k127_6141621_3 Acetyltransferase (GNAT) family K00657 - 2.3.1.57 0.000000000000000000000000000000000000602 152.0
TLS3_k127_6141621_4 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000005284 124.0
TLS3_k127_6141621_6 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528,K16203 GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 0.0000000000001373 71.0
TLS3_k127_6155739_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 3.067e-263 827.0
TLS3_k127_6155739_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.349e-233 743.0
TLS3_k127_6155739_2 Belongs to the pyruvate kinase family K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 349.0
TLS3_k127_6155739_3 Predicted membrane protein (DUF2254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 313.0
TLS3_k127_6185353_0 Cyclase dehydrase - - - 0.000000000000000000000000000000000000000000000000000000000000625 217.0
TLS3_k127_6185353_1 Magnesium transport protein CorA K03284 - - 0.00000000000000000000000000000000000000000000002526 184.0
TLS3_k127_6185353_2 Histidine kinase - - - 0.000000000000000000000000000000000000001789 166.0
TLS3_k127_6185353_3 Transglycosylase associated protein - - - 0.000000000002048 74.0
TLS3_k127_6185877_0 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000001774 172.0
TLS3_k127_6185877_1 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.0000000000000000000000000000000007011 149.0
TLS3_k127_6185877_2 Molybdopterin-guanine dinucleotide biosynthesis protein A K07141 - 2.7.7.76 0.000001442 59.0
TLS3_k127_6215732_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007306 417.0
TLS3_k127_6215732_1 Putative esterase K07017 - - 0.00000000000000000000000000000000000000000000000000000001189 206.0
TLS3_k127_6215732_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000002756 199.0
TLS3_k127_6215732_3 Belongs to the UPF0235 family K09131 - - 0.0000000003883 64.0
TLS3_k127_6215732_4 YGGT family K02221 - - 0.0000000006055 70.0
TLS3_k127_6215732_5 - - - - 0.0002456 48.0
TLS3_k127_6271597_0 PFAM Uncharacterised protein family UPF0182 K09118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005856 558.0
TLS3_k127_6276044_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 7.259e-285 882.0
TLS3_k127_6276044_1 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 3.324e-213 692.0
TLS3_k127_6276044_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 341.0
TLS3_k127_6276044_3 Branched-chain amino acid transport system / permease component K02057,K10440,K17206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 321.0
TLS3_k127_6276044_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 318.0
TLS3_k127_6276044_5 Periplasmic binding protein-like domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000001974 237.0
TLS3_k127_6276044_6 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000005879 192.0
TLS3_k127_6307721_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008968 291.0
TLS3_k127_6307721_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005453 251.0
TLS3_k127_6307721_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000003196 129.0
TLS3_k127_6307721_3 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000001428 118.0
TLS3_k127_6307721_4 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000052 118.0
TLS3_k127_6314005_0 Zn-dependent metallo-hydrolase RNA specificity domain K07577,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 472.0
TLS3_k127_6314005_1 Rhodanese Homology Domain K01011 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016782,GO:0016783,GO:0016784,GO:0031668,GO:0033554,GO:0034641,GO:0042221,GO:0042262,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000009912 142.0
TLS3_k127_6314005_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000001516 128.0
TLS3_k127_6368067_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 533.0
TLS3_k127_6368067_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 297.0
TLS3_k127_6368067_10 Hemerythrin HHE cation binding domain - - - 0.000000002478 65.0
TLS3_k127_6368067_11 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0009201 45.0
TLS3_k127_6368067_2 Beta-lactamase class C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009456 285.0
TLS3_k127_6368067_3 Pfam NUDIX - - - 0.000000000000000000000000000000000000000000000000007128 186.0
TLS3_k127_6368067_5 lactoylglutathione lyase activity K00446 - 1.13.11.2 0.0000000000000000000000000000004666 128.0
TLS3_k127_6368067_6 Universal stress protein family - - - 0.0000000000000000000001224 109.0
TLS3_k127_6368067_7 - - - - 0.000000000000000000001923 108.0
TLS3_k127_6368067_8 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.000000000006881 74.0
TLS3_k127_6368067_9 COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms - - - 0.00000000182 64.0
TLS3_k127_6388753_0 ABC transporter K06147 - - 9.726e-246 779.0
TLS3_k127_6388753_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 400.0
TLS3_k127_6388753_2 PFAM OsmC family protein K07397 - - 0.0000000000000000000003837 108.0
TLS3_k127_6388753_3 PFAM Luciferase-like monooxygenase - - - 0.00002388 49.0
TLS3_k127_6392388_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008601 361.0
TLS3_k127_6392388_1 Acetyltransferase (GNAT) domain - - - 0.0000002405 55.0
TLS3_k127_6400742_0 Belongs to the FGGY kinase family K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 336.0
TLS3_k127_6400742_1 Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 313.0
TLS3_k127_6400742_2 DeoC/LacD family aldolase K01671 - 4.1.2.57 0.000000000000000000000000000000000000000000000000000000003717 217.0
TLS3_k127_6400742_3 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000003351 184.0
TLS3_k127_6465462_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 7.268e-226 712.0
TLS3_k127_6465462_1 Aldehyde dehydrogenase K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 355.0
TLS3_k127_6465462_2 Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 319.0
TLS3_k127_6465462_3 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000001784 160.0
TLS3_k127_6465462_4 YibE/F-like protein - - - 0.000078 52.0
TLS3_k127_6480233_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 451.0
TLS3_k127_6480233_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003771 265.0
TLS3_k127_6480233_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005549 263.0
TLS3_k127_6480233_3 CoA binding domain K01740,K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.5.1.49 0.0000000000000000000000000000003408 128.0
TLS3_k127_6483411_0 Prephenate dehydrogenase K00210,K00220,K04517 - 1.3.1.12,1.3.1.43 0.0000000000000000000000000000000000001885 151.0
TLS3_k127_6483411_1 NUDIX hydrolase - - - 0.000000000000000000000000000000000021 143.0
TLS3_k127_6483411_2 Prolyl oligopeptidase family K06889 - - 0.0000000000003603 78.0
TLS3_k127_6509268_0 dUTP biosynthetic process K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 392.0
TLS3_k127_6509268_1 Electron transfer flavoprotein domain K03522 - - 0.000000000000000000000000000000000000000000001529 168.0
TLS3_k127_6509268_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000002927 166.0
TLS3_k127_6509268_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000412 138.0
TLS3_k127_6512704_0 binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription this protein is involved in detoxification and protection against antimicrobial K03088 - - 0.00000000000000000000005939 108.0
TLS3_k127_6514035_0 PFAM Metallophosphoesterase K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 299.0
TLS3_k127_6514035_1 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000005993 181.0
TLS3_k127_6514035_2 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000009485 161.0
TLS3_k127_6515906_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 528.0
TLS3_k127_6515906_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 297.0
TLS3_k127_6515906_2 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000002864 253.0
TLS3_k127_6515906_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000003837 142.0
TLS3_k127_6515906_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.7.87 0.0000000000000000000000000000003743 136.0
TLS3_k127_6515906_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000004059 115.0
TLS3_k127_6515906_6 Sucrose-6F-phosphate phosphohydrolase - - - 0.00000000000001898 78.0
TLS3_k127_6515906_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000007268 72.0
TLS3_k127_6515906_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000001291 61.0
TLS3_k127_6520582_0 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 324.0
TLS3_k127_6520582_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005923 253.0
TLS3_k127_6520582_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000004323 220.0
TLS3_k127_6520582_3 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.00000000000000000000000000000000000000000000000000004352 198.0
TLS3_k127_6520582_4 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000003602 75.0
TLS3_k127_6531856_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 4.359e-237 759.0
TLS3_k127_6531856_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 415.0
TLS3_k127_6531856_2 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001791 276.0
TLS3_k127_6531856_3 CHAD - - - 0.00000000000000000000000000000000000000000006204 182.0
TLS3_k127_6531856_4 Protein of unknown function (DUF971) - - - 0.0000000000000000000009561 112.0
TLS3_k127_6531856_5 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000209 54.0
TLS3_k127_6532060_0 thought to play an important role in the mineralization of sulfates catalytic activity a phenol sulfate H2O a phenol sulfate K01130 GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004065,GO:0004098,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006687,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0008484,GO:0009987,GO:0012505,GO:0016192,GO:0016787,GO:0016788,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042582,GO:0043167,GO:0043169,GO:0043202,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044255,GO:0044422,GO:0044424,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046872,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0097708,GO:0099503,GO:1901135,GO:1901564,GO:1903509 3.1.6.1 0.0 1241.0
TLS3_k127_6532060_1 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 452.0
TLS3_k127_6532060_2 Ion channel K10716 - - 0.00000000000000000000000000000000000004682 161.0
TLS3_k127_6532060_3 AI-2E family transporter - - - 0.000000000000000000000000000000005066 148.0
TLS3_k127_6532060_4 Phospholipase_D-nuclease N-terminal - - - 0.00000000000000000000000000001801 123.0
TLS3_k127_6532060_5 Sulfate permease family K03321 - - 0.0000000000000000000001616 111.0
TLS3_k127_6532060_6 AI-2E family transporter - - - 0.000000000000000000004223 109.0
TLS3_k127_6532060_7 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000004375 78.0
TLS3_k127_6562235_0 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000001606 140.0
TLS3_k127_6576534_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1090.0
TLS3_k127_6576534_1 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000000000000000000000000007052 184.0
TLS3_k127_6612565_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 441.0
TLS3_k127_6612565_1 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 348.0
TLS3_k127_6612565_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000006302 154.0
TLS3_k127_6612565_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000006621 79.0
TLS3_k127_6614616_0 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009587 319.0
TLS3_k127_6614616_1 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 288.0
TLS3_k127_6614616_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004433 280.0
TLS3_k127_6614616_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001734 238.0
TLS3_k127_6614616_4 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000007205 244.0
TLS3_k127_6614616_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000002399 178.0
TLS3_k127_6614616_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000001531 180.0
TLS3_k127_6614616_7 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000001513 125.0
TLS3_k127_6614616_8 NAD(P)H-binding - - - 0.0000000000000000000000003335 113.0
TLS3_k127_6614616_9 - - - - 0.00000000000009416 76.0
TLS3_k127_6640012_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.051e-225 707.0
TLS3_k127_6640012_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 599.0
TLS3_k127_6640012_10 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.0007555 45.0
TLS3_k127_6640012_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008465 600.0
TLS3_k127_6640012_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 501.0
TLS3_k127_6640012_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 447.0
TLS3_k127_6640012_5 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 399.0
TLS3_k127_6640012_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000009837 241.0
TLS3_k127_6640012_7 Bacterial signalling protein N terminal repeat - - - 0.000000000000000000000000000000000000000000000000000001973 211.0
TLS3_k127_6640012_8 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000003127 172.0
TLS3_k127_6640012_9 Belongs to the alpha-IPM synthase homocitrate synthase family K01649,K15741,K15742 GO:0001101,GO:0003674,GO:0003824,GO:0003852,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006551,GO:0006790,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009414,GO:0009415,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009607,GO:0009625,GO:0009628,GO:0009941,GO:0009987,GO:0010035,GO:0010177,GO:0016053,GO:0016143,GO:0016144,GO:0016740,GO:0016746,GO:0019748,GO:0019752,GO:0019757,GO:0019758,GO:0019760,GO:0019761,GO:0031967,GO:0031975,GO:0042221,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0044550,GO:0046394,GO:0046912,GO:0050896,GO:0051704,GO:0051707,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659,GO:1901700 2.3.3.13,2.3.3.17 0.0003824 50.0
TLS3_k127_6642807_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 497.0
TLS3_k127_6642807_1 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 352.0
TLS3_k127_6642807_2 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000324 216.0
TLS3_k127_6642807_3 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000003907 184.0
TLS3_k127_6642807_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000001682 101.0
TLS3_k127_6642807_5 response regulator - - - 0.0000000000000000001418 89.0
TLS3_k127_6642807_6 - - - - 0.00000002535 62.0
TLS3_k127_6642807_7 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00001612 55.0
TLS3_k127_6682896_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 3.019e-225 709.0
TLS3_k127_6682896_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000002792 179.0
TLS3_k127_669159_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 426.0
TLS3_k127_669159_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 325.0
TLS3_k127_669159_2 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 308.0
TLS3_k127_669159_3 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007198 284.0
TLS3_k127_669159_4 ADP binding - - - 0.000000000000000000000000000000001695 143.0
TLS3_k127_669337_0 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000006518 182.0
TLS3_k127_669337_1 Molybdenum cofactor synthesis domain protein K00963,K03750 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1,2.7.7.9 0.0000000000000000000000000000000000000000001295 168.0
TLS3_k127_6710892_0 Glutamine synthetase type III N terminal K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006953 588.0
TLS3_k127_6710892_1 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006451 317.0
TLS3_k127_6710892_2 PFAM photosystem I assembly BtpA K06971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 290.0
TLS3_k127_6710892_3 Galactose oxidase, central domain K08282 - 2.7.11.1 0.000000000000000000000000003538 123.0
TLS3_k127_6710892_4 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000552 106.0
TLS3_k127_6771011_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.538e-236 749.0
TLS3_k127_6771011_1 Peptidase dimerisation domain K01436,K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 511.0
TLS3_k127_6771011_2 metalloprotease K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001482 261.0
TLS3_k127_6771011_3 Participates in initiation and elongation during chromosome replication K02314,K02316,K17680 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000007341 249.0
TLS3_k127_6771011_4 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000002934 172.0
TLS3_k127_6771011_5 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000002162 161.0
TLS3_k127_6771011_6 - - - - 0.000000000000000000000000000008539 124.0
TLS3_k127_6771011_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000001095 115.0
TLS3_k127_6771011_8 Flotillin K07192 - - 0.00000000000000000001129 104.0
TLS3_k127_6791967_0 Glycosyl hydrolases family 43 K06113 - 3.2.1.99 1.511e-207 666.0
TLS3_k127_6791967_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 456.0
TLS3_k127_6791967_2 galactose-1-phosphate uridylyltransferase K00965 GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 408.0
TLS3_k127_6799889_0 histidine kinase dimerisation and phosphoacceptor region K03406,K07673,K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001788 280.0
TLS3_k127_6799889_1 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000004278 238.0
TLS3_k127_6799889_2 metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006162 228.0
TLS3_k127_6799889_3 Belongs to the UPF0312 family - - - 0.00000000000000000000007884 102.0
TLS3_k127_6799889_4 Universal stress protein family - - - 0.00000000000007278 85.0
TLS3_k127_6821291_0 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000006968 76.0
TLS3_k127_6821291_1 Baseplate J-like protein - - - 0.0000000007029 71.0
TLS3_k127_6824869_0 PFAM YibE F-like protein - - - 0.000000000000000000000000000000000000000000000000000005943 203.0
TLS3_k127_6824869_1 response regulator - - - 0.00000000000000000000000000000000000000005241 164.0
TLS3_k127_6824869_2 Histidine kinase - - - 0.000000000000000000000868 110.0
TLS3_k127_6855219_0 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 441.0
TLS3_k127_6855219_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 368.0
TLS3_k127_6872513_0 Sigma-54 interaction domain K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 559.0
TLS3_k127_6872513_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 429.0
TLS3_k127_6872513_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 409.0
TLS3_k127_6872513_3 SMART Nucleotide binding protein, PINc - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 320.0
TLS3_k127_6872513_4 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000002847 226.0
TLS3_k127_6912027_0 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000447 286.0
TLS3_k127_6912027_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004009 244.0
TLS3_k127_6912027_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000007739 211.0
TLS3_k127_6912027_3 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.000000000000000000000000000000000000000000000000000001756 206.0
TLS3_k127_6912027_4 Carboxylate--amine ligase - - - 0.0000000000000000000000000000000000000000000000175 193.0
TLS3_k127_7005462_0 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000248 261.0
TLS3_k127_7005462_1 PFAM glycosyl transferase, family 51 - - - 0.000000000000000000000000000000000001337 155.0
TLS3_k127_7005462_2 Oxidoreductase molybdopterin binding domain - - - 0.00000000000001068 83.0
TLS3_k127_7025345_0 NAD(P)H-binding K01784,K12448 - 5.1.3.2,5.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 358.0
TLS3_k127_7025345_1 Polysaccharide biosynthesis C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003426 252.0
TLS3_k127_7025345_2 Glycosyl transferases group 1 K00786 - - 0.00000000000000000000000000000000000000000192 171.0
TLS3_k127_7025345_3 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000001152 147.0
TLS3_k127_7025345_4 Polysaccharide deacetylase - - - 0.00000000000000000000000000003742 127.0
TLS3_k127_7025345_5 - - - - 0.00000000000000000003485 105.0
TLS3_k127_7025345_6 biosynthesis protein K08252 - 2.7.10.1 0.000000000000007388 88.0
TLS3_k127_7025345_7 Aminoglycoside phosphotransferase - - - 0.0000000004982 69.0
TLS3_k127_7025345_8 - - - - 0.000235 54.0
TLS3_k127_7025730_0 DEAD DEAH box helicase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 550.0
TLS3_k127_7025730_1 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 481.0
TLS3_k127_7025730_10 - - - - 0.000000000000000000000000000000000000000000000001109 186.0
TLS3_k127_7025730_11 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.00000000000000000000000000000000000000004223 164.0
TLS3_k127_7025730_12 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000005632 141.0
TLS3_k127_7025730_13 diguanylate cyclase - - - 0.000000000000000000000000000000007623 147.0
TLS3_k127_7025730_14 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000005045 120.0
TLS3_k127_7025730_15 DNA binding domain - - - 0.0000000000000000000000000871 111.0
TLS3_k127_7025730_16 Ferric uptake regulator family K03711,K09825 - - 0.0000000000000000000000003986 111.0
TLS3_k127_7025730_17 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.000000000000000000000002086 105.0
TLS3_k127_7025730_18 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000002342 106.0
TLS3_k127_7025730_19 carboxylic ester hydrolase activity - - - 0.000000000000000000003798 106.0
TLS3_k127_7025730_2 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 389.0
TLS3_k127_7025730_20 ACT domain protein - - - 0.00007396 54.0
TLS3_k127_7025730_3 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 374.0
TLS3_k127_7025730_4 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 336.0
TLS3_k127_7025730_5 ABC transporter K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 317.0
TLS3_k127_7025730_6 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000002544 240.0
TLS3_k127_7025730_7 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000007975 250.0
TLS3_k127_7025730_8 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000001519 220.0
TLS3_k127_7025730_9 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000001796 193.0
TLS3_k127_7028184_0 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 524.0
TLS3_k127_7028184_1 C4-dicarboxylate anaerobic carrier - - - 0.0000000000000000000000000001902 132.0
TLS3_k127_7044434_0 AAA ATPase domain - - - 2.514e-252 821.0
TLS3_k127_7044434_1 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 514.0
TLS3_k127_7044434_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03851,K15372 - 2.6.1.55,2.6.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 374.0
TLS3_k127_7044434_3 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 306.0
TLS3_k127_7044434_4 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.0000000000000000000000000000000000000000000000000000000000000000909 241.0
TLS3_k127_7044434_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000001299 222.0
TLS3_k127_7044434_6 OsmC-like protein K04063 - - 0.0000000000000000000000000000000000000007505 157.0
TLS3_k127_7044434_7 Bacterial regulatory proteins, tetR family - - - 0.000000000000000006792 91.0
TLS3_k127_7044434_8 Cysteine-rich secretory protein family - - - 0.00000000001253 75.0
TLS3_k127_7044434_9 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000008142 63.0
TLS3_k127_7046475_1 Cupin domain - - - 0.0000000000000000000000000000000000000000000001145 173.0
TLS3_k127_7046475_3 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000003771 58.0
TLS3_k127_7058569_0 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 595.0
TLS3_k127_7058569_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 426.0
TLS3_k127_7058569_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 356.0
TLS3_k127_7058569_3 Protein of unknown function (DUF3494) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000309 274.0
TLS3_k127_7058569_4 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000001345 233.0
TLS3_k127_7058569_5 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000002556 186.0
TLS3_k127_7058569_6 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000002253 166.0
TLS3_k127_7058569_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000008295 137.0
TLS3_k127_7058569_8 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000182 67.0
TLS3_k127_7058569_9 toxin biosynthetic process K03558 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - 0.00005615 53.0
TLS3_k127_7058695_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 8.038e-201 641.0
TLS3_k127_7058695_1 Threonine synthase K01733 - 4.2.3.1 0.00000000001505 69.0
TLS3_k127_7070091_0 Subtilase family K08651 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000000000002576 218.0
TLS3_k127_7070091_1 - - - - 0.00000000000000000000008059 112.0
TLS3_k127_7125090_0 PA domain - - - 7.368e-240 764.0
TLS3_k127_7125090_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 423.0
TLS3_k127_7125090_2 Transcriptional regulator - - - 0.00000000000000000000000000003178 127.0
TLS3_k127_7126465_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.358e-261 857.0
TLS3_k127_7126465_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 354.0
TLS3_k127_7126465_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000004985 224.0
TLS3_k127_7126465_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000001217 177.0
TLS3_k127_7126465_4 Acetyltransferase (GNAT) family K00657 - 2.3.1.57 0.0000000000000000000000000000000000000001428 159.0
TLS3_k127_7126465_5 Domain of unknown function (DU1801) - - - 0.000000000000000000000009343 105.0
TLS3_k127_7126465_6 - - - - 0.000000000000000007402 95.0
TLS3_k127_7126465_7 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000001436 77.0
TLS3_k127_7126796_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000006742 245.0
TLS3_k127_7126796_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000001258 195.0
TLS3_k127_7153999_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 328.0
TLS3_k127_7153999_1 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000001773 190.0
TLS3_k127_7153999_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000001017 185.0
TLS3_k127_7168176_0 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000007842 217.0
TLS3_k127_7168176_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000002347 151.0
TLS3_k127_7168176_2 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000002571 132.0
TLS3_k127_7168176_3 An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor - - - 0.000000000003384 76.0
TLS3_k127_7172876_0 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000005393 173.0
TLS3_k127_7172876_1 Domain of unknown function (DUF4260) - - - 0.00000000000000000000000004659 115.0
TLS3_k127_7172876_2 Lysine methyltransferase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010565,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018023,GO:0018193,GO:0018205,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031974,GO:0031998,GO:0031999,GO:0032259,GO:0036211,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0043467,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045833,GO:0045922,GO:0046320,GO:0046322,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050994,GO:0050995,GO:0051341,GO:0051354,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1904732,GO:1904733,GO:1904735,GO:1904736 - 0.00000000000001457 76.0
TLS3_k127_7172876_3 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000006911 68.0
TLS3_k127_7172876_4 - - - - 0.00002914 51.0
TLS3_k127_7182929_0 Domain of unknown function (DUF4445) - - - 7.471e-272 855.0
TLS3_k127_7182929_1 COG1410 Methionine synthase I cobalamin-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 430.0
TLS3_k127_7182929_2 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 365.0
TLS3_k127_7182929_3 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000000000000000000000000002351 209.0
TLS3_k127_7182929_4 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000002192 162.0
TLS3_k127_7182929_5 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000001497 127.0
TLS3_k127_7182929_6 Virulence factor - - - 0.00000000000000000000003688 102.0
TLS3_k127_7205592_0 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 301.0
TLS3_k127_7205592_1 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000003805 164.0
TLS3_k127_7236362_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 610.0
TLS3_k127_7236362_1 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000009009 194.0
TLS3_k127_7255698_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 411.0
TLS3_k127_7255698_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 389.0
TLS3_k127_7255698_2 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 291.0
TLS3_k127_7255698_3 PFAM binding-protein-dependent transport systems inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002817 254.0
TLS3_k127_7255698_4 Bacterial extracellular solute-binding protein K11069 - - 0.00000000000000000000000000000000000000000000000000000005352 219.0
TLS3_k127_7255698_5 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000007834 179.0
TLS3_k127_7255698_6 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000002154 148.0
TLS3_k127_7255698_7 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000005152 140.0
TLS3_k127_7255698_8 PFAM zinc finger, SWIM domain protein - - - 0.00000000000000000000000005076 109.0
TLS3_k127_7255698_9 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000002453 87.0
TLS3_k127_7305421_0 ABC transporter K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 458.0
TLS3_k127_7305421_1 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000003764 223.0
TLS3_k127_7305421_2 TrkA-C domain K03499 - - 0.0000000000000000000000000000000000000000000000000000000009616 207.0
TLS3_k127_7305421_3 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000007696 158.0
TLS3_k127_7305421_4 ABC-2 family transporter protein K09694 - - 0.0000001123 63.0
TLS3_k127_7305421_5 coenzyme F420 binding - - - 0.00001172 55.0
TLS3_k127_7316605_0 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 599.0
TLS3_k127_7316605_1 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000004555 91.0
TLS3_k127_7316605_2 transcriptional regulator K13643 - - 0.0000000001739 69.0
TLS3_k127_7326414_0 Fatty acid desaturase K03921 - 1.14.19.11,1.14.19.2,1.14.19.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 361.0
TLS3_k127_7326414_1 cellular response to dsDNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 291.0
TLS3_k127_7326414_2 Protein of unknown function (DUF3037) - - - 0.00001369 49.0
TLS3_k127_7329042_0 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001055 254.0
TLS3_k127_7329042_1 Signal transduction histidine kinase K07777 - 2.7.13.3 0.00000000000000000000000000000000004726 149.0
TLS3_k127_7329042_2 histidine kinase, dimerisation and phosphoacceptor region K07777 - 2.7.13.3 0.000000000000000000000000000001565 139.0
TLS3_k127_7333690_0 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009519 318.0
TLS3_k127_7333690_1 Required for the activity of the bacterial periplasmic transport system of putrescine K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 321.0
TLS3_k127_7333690_3 Belongs to the HAD-like hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001269 218.0
TLS3_k127_7333690_4 2-Nitropropane dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000002419 214.0
TLS3_k127_7333690_5 DNA-binding transcription factor activity K03710 - - 0.0000000000000000000000000000000000000000000000007754 187.0
TLS3_k127_7356456_0 Rossmann-like domain - - - 0.0000000000000000000000000000000000000008815 163.0
TLS3_k127_7356456_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0000000000000000000000882 103.0
TLS3_k127_7361875_0 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 311.0
TLS3_k127_7361875_1 3-oxoacyl-[acyl-carrier-protein] synthase activity K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 288.0
TLS3_k127_7361875_2 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.0000000000000000000001219 105.0
TLS3_k127_7361875_3 amidohydrolase - - - 0.00000000000002199 79.0
TLS3_k127_7365105_0 DNA methylase - - - 0.00000000000000000002298 94.0
TLS3_k127_7365105_1 dienelactone hydrolase - - - 0.00000000000006241 83.0
TLS3_k127_7367922_0 Peptidase family S51 K13282 - 3.4.15.6 0.00000000000000000000000000000000000000000000000000000000007831 227.0
TLS3_k127_7367922_1 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000006933 153.0
TLS3_k127_7367922_2 Glycosyltransferase family 87 K13671 - - 0.0000004207 62.0
TLS3_k127_7367922_3 glutamine amidotransferase - - - 0.0001138 53.0
TLS3_k127_7371250_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 616.0
TLS3_k127_7371250_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 338.0
TLS3_k127_7371250_2 DisA bacterial checkpoint controller nucleotide-binding K18672 GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 0.000000000000000000000000000000000000000000000000000000003681 210.0
TLS3_k127_7371250_3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000007449 120.0
TLS3_k127_7371250_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000001395 100.0
TLS3_k127_7371250_5 YbbR family - - - 0.00002874 57.0
TLS3_k127_7374740_0 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000001621 269.0
TLS3_k127_7374740_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006935 253.0
TLS3_k127_7375396_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 344.0
TLS3_k127_7375396_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000007509 190.0
TLS3_k127_7375396_2 Molybdenum cofactor synthesis domain protein K00963,K03750 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1,2.7.7.9 0.000000000000000000000000000000000000009179 154.0
TLS3_k127_7375396_3 TIGRFAM molybdenum cofactor synthesis domain K03635 - 2.8.1.12 0.000000000000000000000000000000000002137 144.0
TLS3_k127_7379510_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 6.348e-208 655.0
TLS3_k127_7379510_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 421.0
TLS3_k127_7379510_2 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 327.0
TLS3_k127_7379510_3 Homoserine dehydrogenase K00003,K12524 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.3,2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000155 260.0
TLS3_k127_7379510_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000001365 250.0
TLS3_k127_7379510_5 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000001148 212.0
TLS3_k127_7379510_6 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000002145 151.0
TLS3_k127_7387680_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005112 470.0
TLS3_k127_7387680_1 Sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005337 304.0
TLS3_k127_7387680_10 protein with SCP PR1 domains - - - 0.0000000000000000000004021 107.0
TLS3_k127_7387680_11 response regulator - - - 0.000000000000001303 77.0
TLS3_k127_7387680_2 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000003923 246.0
TLS3_k127_7387680_3 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000003396 248.0
TLS3_k127_7387680_4 xylulokinase activity K00848,K00851,K00854,K00862 - 2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5 0.000000000000000000000000000000000000000000000000000000000000004648 238.0
TLS3_k127_7387680_5 BioY family K03523 - - 0.00000000000000000000000000000000000000001455 161.0
TLS3_k127_7387680_6 Protein conserved in bacteria - - - 0.0000000000000000000000000000000002038 148.0
TLS3_k127_7387680_7 Putative sugar-binding domain - - - 0.000000000000000000000000000000002873 141.0
TLS3_k127_7387680_8 peptide catabolic process - - - 0.0000000000000000000000000002471 130.0
TLS3_k127_7387680_9 abc transporter K02049 - - 0.000000000000000000000000427 113.0
TLS3_k127_7412485_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 524.0
TLS3_k127_7412485_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K01919,K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 6.3.2.2 0.000000000000000000000000000000000000000000002687 176.0
TLS3_k127_7412512_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 3.143e-278 860.0
TLS3_k127_7412512_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 0.00000000006437 73.0
TLS3_k127_7414210_0 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 325.0
TLS3_k127_7414210_1 - - - - 0.000000812 53.0
TLS3_k127_7414210_2 Bacterial protein of unknown function (DUF885) - - - 0.000003177 58.0
TLS3_k127_7414210_3 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0001256 54.0
TLS3_k127_7419681_0 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 390.0
TLS3_k127_7419681_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002516 264.0
TLS3_k127_7430561_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 1.417e-196 636.0
TLS3_k127_7430561_1 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 493.0
TLS3_k127_7430561_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0001859 46.0
TLS3_k127_7436948_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 409.0
TLS3_k127_7436948_1 Alpha/beta hydrolase family - - - 0.000000000000000000414 99.0
TLS3_k127_7436948_2 Ethyl tert-butyl ether degradation - - - 0.0000000003381 69.0
TLS3_k127_7436948_3 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.0001477 46.0
TLS3_k127_7451818_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 310.0
TLS3_k127_7451818_1 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008452 280.0
TLS3_k127_7451818_2 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000000000000000000000005829 211.0
TLS3_k127_7451818_3 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000001149 141.0
TLS3_k127_7451818_4 4Fe-4S binding domain - - - 0.0000000000000000000000000006029 115.0
TLS3_k127_7451818_5 Protein of unknown function (DUF1706) - - - 0.00000000004863 75.0
TLS3_k127_7451818_6 Copper-binding protein - - - 0.000004304 54.0
TLS3_k127_7460924_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 2.972e-247 773.0
TLS3_k127_7460924_1 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 609.0
TLS3_k127_7460924_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 358.0
TLS3_k127_7460924_3 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 294.0
TLS3_k127_7460924_4 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000187 261.0
TLS3_k127_7460924_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000001412 154.0
TLS3_k127_7460924_6 glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.000000000000000000000000000006406 124.0
TLS3_k127_7460924_7 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000005071 118.0
TLS3_k127_7460924_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000000001167 102.0
TLS3_k127_7460924_9 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000001736 78.0
TLS3_k127_7468351_0 transporter - - - 0.000000000000000000000000000000000000000000000000000000000000001092 226.0
TLS3_k127_7468351_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000001253 232.0
TLS3_k127_7468351_2 Two component transcriptional regulator, winged helix family K02483 - - 0.0000000000000000000000000000000000000000000000000000000003359 211.0
TLS3_k127_7468351_3 EamA-like transporter family K05786 - - 0.00002868 47.0
TLS3_k127_752979_0 PFAM ABC transporter related K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 340.0
TLS3_k127_752979_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000003842 149.0
TLS3_k127_7538665_0 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 464.0
TLS3_k127_7538665_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 411.0
TLS3_k127_7538665_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000004095 157.0
TLS3_k127_7538665_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000008747 145.0
TLS3_k127_7538665_4 dna ligase K01971 - 6.5.1.1 0.0000000000000000000003787 106.0
TLS3_k127_7538665_5 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000024 92.0
TLS3_k127_7538665_6 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.00000000001509 77.0
TLS3_k127_7546557_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 573.0
TLS3_k127_7546557_1 Cyclic nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000007375 251.0
TLS3_k127_7546557_2 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944 - 0.00000000000000000000000000000000000000000000001168 186.0
TLS3_k127_7546557_3 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000003139 85.0
TLS3_k127_7546557_4 - - - - 0.00000005014 61.0
TLS3_k127_7628713_0 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K04091 - 1.14.14.5 0.000000000000000000000000000000000000000000000000000000000000000003439 238.0
TLS3_k127_7628713_1 Iron dependent repressor, N-terminal DNA binding domain - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000001825 74.0
TLS3_k127_7638602_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 367.0
TLS3_k127_7638602_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008145 248.0
TLS3_k127_7638602_2 - - - - 0.0000000001762 68.0
TLS3_k127_7645976_0 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002654 238.0
TLS3_k127_7645976_1 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000008041 215.0
TLS3_k127_7645976_2 Belongs to the UPF0354 family - - - 0.0001913 53.0
TLS3_k127_7708121_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 3.005e-204 657.0
TLS3_k127_7708121_1 Type II/IV secretion system protein K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 541.0
TLS3_k127_7708121_2 Sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 312.0
TLS3_k127_7708121_3 PFAM phosphoesterase, PA-phosphatase related - - - 0.0000000000000002732 90.0
TLS3_k127_7708121_4 Transglycosylase associated protein - - - 0.0000000000000006406 80.0
TLS3_k127_7708121_5 Helix-turn-helix XRE-family like proteins - - - 0.0000003027 63.0
TLS3_k127_7708121_6 Helix-turn-helix XRE-family like proteins - - - 0.0004185 47.0
TLS3_k127_7710781_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 487.0
TLS3_k127_7742672_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 299.0
TLS3_k127_7742672_1 WYL domain K07012,K13572 - - 0.000000000000000000000000000000000000000000000000000000000001089 229.0
TLS3_k127_7742672_2 peptidase inhibitor activity - - - 0.0000003187 61.0
TLS3_k127_7760873_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 334.0
TLS3_k127_7760873_1 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 320.0
TLS3_k127_7760873_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 292.0
TLS3_k127_7760873_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000002288 255.0
TLS3_k127_7760873_4 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000001818 203.0
TLS3_k127_7760873_5 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000002169 190.0
TLS3_k127_7760873_6 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K03789 - 2.3.1.128 0.000000000000000000000000331 114.0
TLS3_k127_7760873_7 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.000000000000000000001623 102.0
TLS3_k127_7760873_8 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000003546 101.0
TLS3_k127_7760873_9 AI-2E family transporter - - - 0.00000000000000005524 94.0
TLS3_k127_7761844_0 PFAM Prolyl oligopeptidase family - - - 2.51e-201 648.0
TLS3_k127_7761844_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 549.0
TLS3_k127_7761844_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 529.0
TLS3_k127_7761844_3 Sodium/hydrogen exchanger family K03316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 404.0
TLS3_k127_7761844_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 312.0
TLS3_k127_7761844_5 acetyltransferase - - - 0.0000000000000000000001715 110.0
TLS3_k127_7771698_0 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 361.0
TLS3_k127_7771698_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 348.0
TLS3_k127_7771698_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 328.0
TLS3_k127_7771698_3 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 289.0
TLS3_k127_7771698_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.246,4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007656 303.0
TLS3_k127_7771698_5 endonuclease III K03575 - - 0.0000000000000000000000000000000000000000000000000000000000004648 225.0
TLS3_k127_7771698_6 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000002271 139.0
TLS3_k127_7771698_7 response regulator - - - 0.00000000000116 78.0
TLS3_k127_7808959_0 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 499.0
TLS3_k127_7808959_1 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 448.0
TLS3_k127_7808959_2 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 445.0
TLS3_k127_7808959_3 Inositol monophosphatase family K01092,K05602 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008934,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016053,GO:0016137,GO:0016138,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052745,GO:0052803,GO:0052834,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659 3.1.3.15,3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000986 233.0
TLS3_k127_7819193_0 FAD dependent oxidoreductase central domain - - - 2.651e-255 809.0
TLS3_k127_7819193_1 Choline ethanolamine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001887 260.0
TLS3_k127_7819193_2 acid phosphatase activity K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000001256 195.0
TLS3_k127_7819193_3 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.00000000000000000000000000000000001854 141.0
TLS3_k127_783431_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 360.0
TLS3_k127_783431_1 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000003684 235.0
TLS3_k127_7834844_0 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 308.0
TLS3_k127_7834844_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000007452 193.0
TLS3_k127_7834844_2 Catalyzes the alpha,beta-elimination reaction of D- cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine K05396,K17950 - 4.4.1.15,4.4.1.25 0.0000000000000001886 82.0
TLS3_k127_7837288_0 hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000009827 228.0
TLS3_k127_7837288_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001992 230.0
TLS3_k127_7837288_2 ABC-type cobalt transport system, permease component K16925 - - 0.0000000000000000000000000000001346 131.0
TLS3_k127_7837288_3 Dodecin K09165 - - 0.000000000002716 66.0
TLS3_k127_7838535_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 349.0
TLS3_k127_7838535_1 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000000000008406 247.0
TLS3_k127_7838535_2 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000009682 234.0
TLS3_k127_7838535_3 Exonuclease K07502 - - 0.00000000000000000000000000000000000006097 162.0
TLS3_k127_7838535_4 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000000000001088 145.0
TLS3_k127_7838535_5 pfkB family carbohydrate kinase - - - 0.000003635 58.0
TLS3_k127_7852798_0 Anticodon-binding domain of tRNA K01870 - 6.1.1.5 0.0 1125.0
TLS3_k127_7852948_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000003815 198.0
TLS3_k127_7878690_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01476,K01480 - 3.5.3.1,3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000008729 230.0
TLS3_k127_7878690_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000001563 151.0
TLS3_k127_7878690_2 Protein of unknown function (DUF2652) - - - 0.000000000000000000000004797 107.0
TLS3_k127_7878690_3 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000002724 65.0
TLS3_k127_7916998_0 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 390.0
TLS3_k127_7916998_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 370.0
TLS3_k127_7916998_2 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000001899 240.0
TLS3_k127_7916998_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000001077 211.0
TLS3_k127_7916998_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000007261 108.0
TLS3_k127_7918636_0 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 616.0
TLS3_k127_7918636_1 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 481.0
TLS3_k127_7918636_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 319.0
TLS3_k127_7918636_3 Transcriptional regulatory protein, C terminal K07669,K07672 GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000005694 200.0
TLS3_k127_7918636_4 His Kinase A (phosphoacceptor) domain K14982 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.000000000000000000000000000000000000000000002533 182.0
TLS3_k127_7925795_0 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 461.0
TLS3_k127_7925795_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 400.0
TLS3_k127_7925795_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000003884 114.0
TLS3_k127_7945395_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 5.447e-209 664.0
TLS3_k127_7945395_1 solute:proton antiporter activity K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 558.0
TLS3_k127_7945395_10 Major facilitator Superfamily - - - 0.0000000000000005204 91.0
TLS3_k127_7945395_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 295.0
TLS3_k127_7945395_3 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002658 268.0
TLS3_k127_7945395_4 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000000586 199.0
TLS3_k127_7945395_5 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000004423 183.0
TLS3_k127_7945395_6 Belongs to the urease gamma subunit family K14048 - 3.5.1.5 0.00000000000000000000000000000000000000000233 165.0
TLS3_k127_7945395_7 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.00000000000000000000000000000000000001735 157.0
TLS3_k127_7945395_8 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000001506 126.0
TLS3_k127_7945395_9 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000009247 96.0
TLS3_k127_8003516_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 356.0
TLS3_k127_8003516_1 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 313.0
TLS3_k127_8003516_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001584 277.0
TLS3_k127_8003516_3 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000003565 275.0
TLS3_k127_8003516_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000003433 208.0
TLS3_k127_8003516_5 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000008504 192.0
TLS3_k127_8003516_6 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000003217 154.0
TLS3_k127_8003516_7 - - - - 0.00000000000000001643 89.0
TLS3_k127_8003516_8 CarboxypepD_reg-like domain K13276 - - 0.0002117 53.0
TLS3_k127_8004951_0 Transcriptional regulator sugar kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 484.0
TLS3_k127_8004951_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 468.0
TLS3_k127_8004951_2 AP endonuclease family 2 C terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 458.0
TLS3_k127_8004951_3 Periplasmic binding protein-like domain K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 413.0
TLS3_k127_8004951_4 Bacterial extracellular solute-binding protein K10117 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 413.0
TLS3_k127_8004951_5 Binding-protein-dependent transport system inner membrane component K02025,K10118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 364.0
TLS3_k127_8004951_6 Binding-protein-dependent transport system inner membrane component K02026,K10119,K17243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 342.0
TLS3_k127_8004951_7 Belongs to the glycosyl hydrolase 3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000235 267.0
TLS3_k127_8008052_0 E1-E2 ATPase K01537,K12953 - 3.6.3.8 0.0 1060.0
TLS3_k127_8008052_1 Major facilitator Superfamily - - - 1.035e-220 698.0
TLS3_k127_8008052_2 C4-dicarboxylate anaerobic carrier - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 601.0
TLS3_k127_8008052_3 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.00000000003233 65.0
TLS3_k127_8008052_4 - - - - 0.0000000008232 67.0
TLS3_k127_8008052_5 - - - - 0.000001176 56.0
TLS3_k127_802798_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 365.0
TLS3_k127_802798_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009088 325.0
TLS3_k127_802798_2 zinc metalloprotease K04771,K11749,K16922 GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107 0.00000000000000000000000000000000000000000000000000008418 203.0
TLS3_k127_8051804_0 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 333.0
TLS3_k127_8051804_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000001214 163.0
TLS3_k127_8051804_2 PFAM ABC transporter related K02049 - - 0.00000000000000000001541 93.0
TLS3_k127_8075270_0 N-terminal domain of (some) glycogen debranching enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 556.0
TLS3_k127_8075270_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 366.0
TLS3_k127_8075270_2 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000137 125.0
TLS3_k127_8083953_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0008150,GO:0040007 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 495.0
TLS3_k127_8083953_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001147 280.0
TLS3_k127_8083953_2 AIR synthase related protein, C-terminal domain K01933 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016882,GO:0044424,GO:0044444,GO:0044464 6.3.3.1 0.000000000000000001 101.0
TLS3_k127_8159552_0 Aminotransferase class-III K00823 - 2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 534.0
TLS3_k127_8159552_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005032 290.0
TLS3_k127_8159552_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000001934 232.0
TLS3_k127_8159552_3 LysE type translocator - - - 0.0000000000000000000000000000000000000001038 158.0
TLS3_k127_8171554_0 Evidence 5 No homology to any previously reported sequences - - - 6.552e-269 861.0
TLS3_k127_8171554_1 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 5.161e-235 740.0
TLS3_k127_8171554_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 429.0
TLS3_k127_8171554_3 cyclase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 399.0
TLS3_k127_8171554_4 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 392.0
TLS3_k127_8171554_5 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000001365 188.0
TLS3_k127_8171554_6 Transcriptional regulator K22293 - - 0.0000000000000000000000000000000000000000000000002097 188.0
TLS3_k127_8171554_7 Psort location Cytoplasmic, score K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000408 177.0
TLS3_k127_8172948_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 379.0
TLS3_k127_8172948_1 ATPases associated with a variety of cellular activities K10112,K10195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 346.0
TLS3_k127_8172948_2 pfam nudix K01515 - 3.6.1.13 0.000000000000000000000000000000000000003576 161.0
TLS3_k127_8172948_3 Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol K15520 GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701 2.3.1.189 0.000000000000000000000006005 115.0
TLS3_k127_8172948_4 Tetratricopeptide repeat - - - 0.000000000000000004986 92.0
TLS3_k127_8185374_0 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 415.0
TLS3_k127_8211025_0 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002269 257.0
TLS3_k127_8211025_1 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000299 229.0
TLS3_k127_8211025_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000002962 82.0
TLS3_k127_8224731_0 PFAM catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000001721 224.0
TLS3_k127_8224731_1 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000004696 173.0
TLS3_k127_8224731_2 Belongs to the HpcH HpaI aldolase family K01644,K08691 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0015977,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0043167,GO:0043169,GO:0043427,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0047777,GO:0050083,GO:0071704 4.1.3.24,4.1.3.25,4.1.3.34 0.0000000000000000002455 103.0
TLS3_k127_8224731_3 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627,K00658 - 2.3.1.12,2.3.1.61 0.0000000000002196 71.0
TLS3_k127_8224731_4 MaoC domain-containing protein dehydratase - - - 0.00000000004256 66.0
TLS3_k127_8248923_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 443.0
TLS3_k127_8248923_1 tRNA binding K04566 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008 430.0
TLS3_k127_8248923_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000003841 217.0
TLS3_k127_8248923_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000002197 158.0
TLS3_k127_8248923_4 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000000000009779 122.0
TLS3_k127_8248923_5 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.11 0.000001634 60.0
TLS3_k127_8321561_0 FAD dependent oxidoreductase central domain - - - 0.0 1196.0
TLS3_k127_8321561_1 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007706 273.0
TLS3_k127_8321561_2 Electron transfer flavoprotein, beta subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002083 260.0
TLS3_k127_8321561_3 helix_turn_helix isocitrate lyase regulation K13641 - - 0.000000000000000000000000000000000005585 148.0
TLS3_k127_8364816_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 1.299e-307 959.0
TLS3_k127_8364816_1 F420-dependent oxidoreductase, G6PDH family K15510 - 1.1.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005605 468.0
TLS3_k127_8364816_10 Cupin 2, conserved barrel domain protein K05916 - 1.14.12.17 0.00001351 53.0
TLS3_k127_8364816_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 478.0
TLS3_k127_8364816_3 Von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 423.0
TLS3_k127_8364816_4 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 401.0
TLS3_k127_8364816_5 Aminotransferase class-V K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 396.0
TLS3_k127_8364816_6 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 379.0
TLS3_k127_8364816_7 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000001929 138.0
TLS3_k127_8364816_8 GntR family transcriptional regulator - - - 0.000000000000000000000000000001714 130.0
TLS3_k127_8364816_9 NUDIX domain - - - 0.0000000000000000000000000265 116.0
TLS3_k127_8379598_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 308.0
TLS3_k127_8379598_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000003351 58.0
TLS3_k127_8379598_2 PFAM blue (type 1) copper domain protein - - - 0.00006766 51.0
TLS3_k127_8387486_0 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 315.0
TLS3_k127_8387486_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000002689 82.0
TLS3_k127_8387486_2 Ribbon-helix-helix protein, copG family - - - 0.000000001835 61.0
TLS3_k127_8407168_0 PspC domain - - - 0.00000000001283 72.0
TLS3_k127_8407168_1 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.0007574 51.0
TLS3_k127_8453371_0 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 452.0
TLS3_k127_8453371_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 380.0
TLS3_k127_8453371_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 363.0
TLS3_k127_8453371_3 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009977 258.0
TLS3_k127_8453371_4 Domain of unknown function (DUF4287) - - - 0.000000000000000000000000000000000000000000000005241 179.0
TLS3_k127_8453371_5 DNA binding - - - 0.0000000000000000000000000007153 126.0
TLS3_k127_874412_0 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001401 256.0
TLS3_k127_874412_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000973 191.0
TLS3_k127_874412_2 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000000000000000000000000005426 165.0
TLS3_k127_874412_3 Histidine Phosphotransfer domain K02488,K11443 - 2.7.7.65 0.0000000000000000000000000000000000001594 164.0
TLS3_k127_874412_4 Glycosyl hydrolases family 18 - - - 0.00000000000000001348 96.0
TLS3_k127_874412_5 Predicted integral membrane protein (DUF2269) - - - 0.00000000000001058 85.0
TLS3_k127_874412_6 PFAM alpha beta hydrolase fold K01259 - 3.4.11.5 0.000000004826 59.0
TLS3_k127_878423_0 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000001733 187.0
TLS3_k127_878423_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000001063 187.0
TLS3_k127_878423_2 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000002281 130.0
TLS3_k127_878423_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000001797 123.0
TLS3_k127_878423_4 Binds the 23S rRNA K02909 - - 0.000000000000000000000005542 105.0
TLS3_k127_878423_5 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000005898 101.0
TLS3_k127_878423_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000000004876 75.0
TLS3_k127_878423_7 protein conserved in bacteria (DUF2344) - - - 0.00000000009569 72.0
TLS3_k127_908174_0 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 442.0
TLS3_k127_908174_1 dna ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001985 278.0
TLS3_k127_908174_2 YCII-related domain - - - 0.00000000000000000000000000000001141 135.0
TLS3_k127_948425_0 Proline racemase K01777 - 5.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 320.0
TLS3_k127_948425_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000001305 178.0
TLS3_k127_948425_2 Bacterial protein of unknown function (DUF885) - - - 0.00000002314 57.0
TLS3_k127_965182_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 6.611e-223 704.0
TLS3_k127_965182_1 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003579 287.0
TLS3_k127_965182_10 acetyltransferase K03789,K06323 - 2.3.1.128 0.00000000000003494 85.0
TLS3_k127_965182_11 Alpha beta hydrolase - - - 0.00000000000003817 87.0
TLS3_k127_965182_13 DnaJ molecular chaperone homology domain K05516 - - 0.00000003614 64.0
TLS3_k127_965182_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000435 247.0
TLS3_k127_965182_3 Domain of unknown function (DUF4261) - - - 0.00000000000000000000000000000000000005884 157.0
TLS3_k127_965182_4 belongs to the thioredoxin family K03671 - - 0.000000000000000000000000001112 123.0
TLS3_k127_965182_5 Zincin-like metallopeptidase - - - 0.0000000000000000000000002218 110.0
TLS3_k127_965182_6 Nitroreductase - - - 0.000000000000000000004785 105.0
TLS3_k127_965182_7 BAAT Acyl-CoA thioester hydrolase - - - 0.000000000000000001571 100.0
TLS3_k127_965182_8 Cobalamin B12-binding domain - - - 0.00000000000000017 89.0
TLS3_k127_965182_9 Transcriptional K03892 - - 0.000000000000006663 83.0
TLS3_k127_980228_0 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000009938 237.0
TLS3_k127_980228_1 F420-dependent oxidoreductase, Rv1855c family - - - 0.00000000000000000000000000000000002081 147.0
TLS3_k127_980228_2 Acetyltransferase (GNAT) family - - - 0.0000000000000000000001831 109.0
TLS3_k127_980228_3 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000002173 92.0
TLS3_k127_983337_0 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 324.0
TLS3_k127_983337_1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000001331 205.0
TLS3_k127_983337_2 Periplasmic component of the Tol biopolymer transport system - - - 0.00000817 57.0