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Overview

ID MAG04060
Name TLS3_bin.5
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Planctomycetota
Class Phycisphaerae
Order Phycisphaerales
Family SM1A02
Genus JAKEEP01
Species
Assembly information
Completeness (%) 98.12
Contamination (%) 2.1
GC content (%) 58.0
N50 (bp) 140,119
Genome size (bp) 3,550,058

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2431

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1051146_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 6.653e-255 818.0
TLS3_k127_1051146_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 558.0
TLS3_k127_1051146_10 ZIP Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000001277 235.0
TLS3_k127_1051146_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000405 235.0
TLS3_k127_1051146_12 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000000000000000005958 181.0
TLS3_k127_1051146_13 MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000005428 162.0
TLS3_k127_1051146_14 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000004841 140.0
TLS3_k127_1051146_15 type IV pilus modification protein PilV K02458,K02671,K02681 - - 0.000000000000000000002046 104.0
TLS3_k127_1051146_16 von Willebrand factor, type A - - - 0.0000000000000000009878 100.0
TLS3_k127_1051146_17 biopolymer transport protein K03559 - - 0.00000000000001282 81.0
TLS3_k127_1051146_19 Biopolymer transport protein K03559 - - 0.00002499 52.0
TLS3_k127_1051146_2 COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 528.0
TLS3_k127_1051146_20 Phage integrase family - - - 0.00003149 46.0
TLS3_k127_1051146_21 von Willebrand factor (vWF) type A domain K07114 - - 0.00004285 55.0
TLS3_k127_1051146_22 DoxX - - - 0.00007066 54.0
TLS3_k127_1051146_23 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0002435 55.0
TLS3_k127_1051146_3 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 523.0
TLS3_k127_1051146_4 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 505.0
TLS3_k127_1051146_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 414.0
TLS3_k127_1051146_6 COG0639 Diadenosine tetraphosphatase and related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 345.0
TLS3_k127_1051146_7 protein secretion K02460 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 360.0
TLS3_k127_1051146_8 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007959 336.0
TLS3_k127_1051146_9 COG0530 Ca2 Na antiporter K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004565 259.0
TLS3_k127_106506_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0 1475.0
TLS3_k127_106506_1 HsdM N-terminal domain K03427 - 2.1.1.72 0.0 1149.0
TLS3_k127_106506_10 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 588.0
TLS3_k127_106506_100 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000003134 136.0
TLS3_k127_106506_101 - - - - 0.00000000000000000000000000000001224 131.0
TLS3_k127_106506_102 - - - - 0.00000000000000000000000000000003097 130.0
TLS3_k127_106506_103 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 0.00000000000000000000000000000003297 139.0
TLS3_k127_106506_105 Belongs to the flagella basal body rod proteins family K02388 - - 0.00000000000000000000000000000008477 128.0
TLS3_k127_106506_106 Uncharacterized conserved protein (DUF2190) - - - 0.00000000000000000000000000000009138 127.0
TLS3_k127_106506_107 - - - - 0.0000000000000000000000000000003373 130.0
TLS3_k127_106506_108 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000005136 130.0
TLS3_k127_106506_11 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 504.0
TLS3_k127_106506_111 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000002367 117.0
TLS3_k127_106506_112 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000009612 115.0
TLS3_k127_106506_113 - - - - 0.000000000000000000000000001099 120.0
TLS3_k127_106506_114 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000557 119.0
TLS3_k127_106506_115 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000000004227 114.0
TLS3_k127_106506_116 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000001123 120.0
TLS3_k127_106506_117 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000000000000003544 106.0
TLS3_k127_106506_118 - - - - 0.000000000000000000000003234 112.0
TLS3_k127_106506_119 Flagellar hook-basal body complex protein FliE K02408 - - 0.000000000000000000000005684 105.0
TLS3_k127_106506_12 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 502.0
TLS3_k127_106506_120 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000006507 98.0
TLS3_k127_106506_121 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000005429 93.0
TLS3_k127_106506_122 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000004451 101.0
TLS3_k127_106506_124 membrane K08978 - - 0.0000000000000000004601 93.0
TLS3_k127_106506_125 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000005409 94.0
TLS3_k127_106506_126 - - - - 0.0000000000000000009633 89.0
TLS3_k127_106506_127 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 0.000000000000000008223 86.0
TLS3_k127_106506_128 - - - - 0.0000000000000001375 89.0
TLS3_k127_106506_129 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000002021 80.0
TLS3_k127_106506_13 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 503.0
TLS3_k127_106506_130 TIGRFAM DNA binding domain protein, excisionase family - - - 0.0000000000000003907 81.0
TLS3_k127_106506_131 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000000002267 82.0
TLS3_k127_106506_132 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000008892 77.0
TLS3_k127_106506_133 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000002623 82.0
TLS3_k127_106506_134 Domain of unknown function (DUF378) K09779 - - 0.000000000001675 71.0
TLS3_k127_106506_135 - - - - 0.000000000005629 73.0
TLS3_k127_106506_138 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template - - - 0.0000000003059 65.0
TLS3_k127_106506_14 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 466.0
TLS3_k127_106506_140 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 0.0000000003932 62.0
TLS3_k127_106506_141 - - - - 0.000000002269 63.0
TLS3_k127_106506_144 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000001332 57.0
TLS3_k127_106506_145 Transposase IS200 like - - - 0.00000001864 63.0
TLS3_k127_106506_147 Flagellar hook-length control protein K02414 - - 0.00000008808 65.0
TLS3_k127_106506_148 PFAM flagellar hook capping protein K02389 - - 0.0000001203 61.0
TLS3_k127_106506_15 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 453.0
TLS3_k127_106506_151 PFAM SNARE associated Golgi protein - - - 0.000000395 62.0
TLS3_k127_106506_154 - - - - 0.00002673 55.0
TLS3_k127_106506_156 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00004129 48.0
TLS3_k127_106506_157 Prokaryotic N-terminal methylation motif - - - 0.00006038 55.0
TLS3_k127_106506_158 Glycine zipper - - - 0.00009044 53.0
TLS3_k127_106506_159 COG1317 Flagellar biosynthesis type III secretory pathway protein K02411 - - 0.0001015 53.0
TLS3_k127_106506_16 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009359 434.0
TLS3_k127_106506_160 heavy metal transport detoxification protein K07213 - - 0.0001179 51.0
TLS3_k127_106506_161 - K03641 - - 0.0004576 51.0
TLS3_k127_106506_162 DinB family - - - 0.0009519 51.0
TLS3_k127_106506_17 TIGRFAM ATPase, FliI YscN family K02412 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 427.0
TLS3_k127_106506_18 flagellar motor switch protein K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 409.0
TLS3_k127_106506_19 Glycogen debranching enzyme N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 424.0
TLS3_k127_106506_2 Phage terminase large subunit (GpA) - - - 0.0 1125.0
TLS3_k127_106506_20 PFAM ATP dependent DNA ligase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 408.0
TLS3_k127_106506_21 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 405.0
TLS3_k127_106506_22 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008582 403.0
TLS3_k127_106506_23 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 419.0
TLS3_k127_106506_24 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007369 390.0
TLS3_k127_106506_25 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 392.0
TLS3_k127_106506_26 Flagellar hook protein FlgE K02390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 397.0
TLS3_k127_106506_27 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 379.0
TLS3_k127_106506_28 Transfers the fatty acyl group on membrane lipoproteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 384.0
TLS3_k127_106506_29 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 379.0
TLS3_k127_106506_3 ParB-like nuclease domain - - - 3.406e-221 694.0
TLS3_k127_106506_30 phage plasmid primase K06919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 391.0
TLS3_k127_106506_31 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 372.0
TLS3_k127_106506_32 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009231 376.0
TLS3_k127_106506_33 PP-loop superfamily ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 359.0
TLS3_k127_106506_34 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 342.0
TLS3_k127_106506_35 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 362.0
TLS3_k127_106506_36 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 340.0
TLS3_k127_106506_37 Belongs to the peptidase S41A family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 351.0
TLS3_k127_106506_38 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 336.0
TLS3_k127_106506_39 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 325.0
TLS3_k127_106506_4 Phage portal protein, lambda family - - - 8.107e-218 690.0
TLS3_k127_106506_40 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 323.0
TLS3_k127_106506_41 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 317.0
TLS3_k127_106506_42 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 310.0
TLS3_k127_106506_43 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 308.0
TLS3_k127_106506_44 PFAM restriction modification system DNA specificity domain K01154 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 321.0
TLS3_k127_106506_45 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 297.0
TLS3_k127_106506_46 UV-endonuclease UvdE K13281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 319.0
TLS3_k127_106506_47 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007774 282.0
TLS3_k127_106506_48 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001638 274.0
TLS3_k127_106506_49 PFAM NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008391 281.0
TLS3_k127_106506_5 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 2.132e-215 679.0
TLS3_k127_106506_50 protein (ATP-grasp superfamily) K07159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002804 277.0
TLS3_k127_106506_51 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002884 270.0
TLS3_k127_106506_52 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009931 268.0
TLS3_k127_106506_53 Iron/manganese superoxide dismutases, alpha-hairpin domain K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000315 263.0
TLS3_k127_106506_54 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005041 261.0
TLS3_k127_106506_55 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007161 258.0
TLS3_k127_106506_56 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008151 254.0
TLS3_k127_106506_57 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000002986 248.0
TLS3_k127_106506_58 COG1253 Hemolysins and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008149 254.0
TLS3_k127_106506_59 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008247 252.0
TLS3_k127_106506_6 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 1.155e-208 661.0
TLS3_k127_106506_60 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000002205 243.0
TLS3_k127_106506_61 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000004234 223.0
TLS3_k127_106506_62 PFAM phosphoesterase PA-phosphatase related K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000002131 226.0
TLS3_k127_106506_63 TIR domain - - - 0.0000000000000000000000000000000000000000000000000000000000001825 224.0
TLS3_k127_106506_64 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000000000000000000000001607 217.0
TLS3_k127_106506_65 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000002265 219.0
TLS3_k127_106506_66 - - - - 0.000000000000000000000000000000000000000000000000000000000002926 217.0
TLS3_k127_106506_67 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000002914 213.0
TLS3_k127_106506_68 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001591 211.0
TLS3_k127_106506_69 signal peptidase-like protein - - - 0.0000000000000000000000000000000000000000000000000000000003101 219.0
TLS3_k127_106506_7 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 6.049e-203 644.0
TLS3_k127_106506_70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000007657 201.0
TLS3_k127_106506_71 protein trimerization K20543 - - 0.000000000000000000000000000000000000000000000000000000008286 225.0
TLS3_k127_106506_72 - - - - 0.00000000000000000000000000000000000000000000000000000002472 206.0
TLS3_k127_106506_73 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000005433 199.0
TLS3_k127_106506_74 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000005718 192.0
TLS3_k127_106506_75 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000001931 205.0
TLS3_k127_106506_76 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000006442 185.0
TLS3_k127_106506_77 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000004125 204.0
TLS3_k127_106506_78 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000001805 182.0
TLS3_k127_106506_79 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000002121 179.0
TLS3_k127_106506_8 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 6.93e-201 641.0
TLS3_k127_106506_80 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000002828 177.0
TLS3_k127_106506_81 Domain of unknown function (DUF4826) - - - 0.0000000000000000000000000000000000000000000000004817 180.0
TLS3_k127_106506_82 PAS fold - - - 0.000000000000000000000000000000000000000000000003284 195.0
TLS3_k127_106506_83 Flagellar biosynthesis type III secretory pathway K02409 - - 0.000000000000000000000000000000000000000000000005391 192.0
TLS3_k127_106506_84 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000002521 179.0
TLS3_k127_106506_85 Bacterial PH domain K08981 - - 0.0000000000000000000000000000000000000000000003286 176.0
TLS3_k127_106506_87 ribosomal protein l17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000003602 169.0
TLS3_k127_106506_88 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000001525 167.0
TLS3_k127_106506_9 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 2.297e-197 622.0
TLS3_k127_106506_90 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000005117 154.0
TLS3_k127_106506_91 Bacterial PH domain K08981 - - 0.00000000000000000000000000000000000000008212 160.0
TLS3_k127_106506_92 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000001549 158.0
TLS3_k127_106506_93 Protein of unknown function (DUF541) K09797 - - 0.0000000000000000000000000000000000000001861 162.0
TLS3_k127_106506_94 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000001964 151.0
TLS3_k127_106506_95 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000633 144.0
TLS3_k127_106506_96 SMI1-KNR4 cell-wall - - - 0.000000000000000000000000000000000004191 142.0
TLS3_k127_106506_97 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000187 137.0
TLS3_k127_106506_98 - - - - 0.00000000000000000000000000000000005885 141.0
TLS3_k127_106506_99 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000006105 137.0
TLS3_k127_1290649_0 2-methylcitrate dehydratase activity K01720 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.79 2.179e-210 674.0
TLS3_k127_1290649_1 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 611.0
TLS3_k127_1290649_10 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 338.0
TLS3_k127_1290649_11 competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 345.0
TLS3_k127_1290649_12 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002207 274.0
TLS3_k127_1290649_13 protein methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002661 271.0
TLS3_k127_1290649_14 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000004018 266.0
TLS3_k127_1290649_15 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000008803 246.0
TLS3_k127_1290649_16 COG2812 DNA polymerase III, gamma tau subunits K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000007228 239.0
TLS3_k127_1290649_17 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000002054 242.0
TLS3_k127_1290649_18 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000003358 248.0
TLS3_k127_1290649_19 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000001619 235.0
TLS3_k127_1290649_2 Tricorn protease C1 domain K08676 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 641.0
TLS3_k127_1290649_20 Bacterial transcriptional repressor C-terminal - - - 0.00000000000000000000000000000000000000000000000000000009703 213.0
TLS3_k127_1290649_21 coenzyme binding K07071 - - 0.00000000000000000000000000000000000000000000000000003829 196.0
TLS3_k127_1290649_22 Domain of unknown function (DUF4411) - - - 0.000000000000000000000000000000000000000000001506 169.0
TLS3_k127_1290649_23 - - - - 0.0000000000000000000000000000000000000003546 157.0
TLS3_k127_1290649_24 Thiol-disulfide oxidoreductase DCC - - - 0.000000000000000000000000000000000000003318 151.0
TLS3_k127_1290649_25 - K07071 - - 0.00000000000000000000000000000000000434 147.0
TLS3_k127_1290649_26 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.00000000000000000000000000000000002005 149.0
TLS3_k127_1290649_27 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000003532 128.0
TLS3_k127_1290649_29 Thioredoxin-like - - - 0.000000000000000000000000000002928 135.0
TLS3_k127_1290649_3 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 499.0
TLS3_k127_1290649_30 - - - - 0.0000000000000000000000000006525 128.0
TLS3_k127_1290649_31 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000001402 119.0
TLS3_k127_1290649_33 - - - - 0.000000000000000000000275 98.0
TLS3_k127_1290649_34 23S rRNA-intervening sequence protein - - - 0.0000000000000000000005813 99.0
TLS3_k127_1290649_35 PFAM DSBA oxidoreductase - - - 0.000000000000000000001853 110.0
TLS3_k127_1290649_36 Peptidase family M48 - - - 0.000000000000000001142 98.0
TLS3_k127_1290649_37 glyoxalase III activity K00799 - 2.5.1.18 0.00000000000004095 85.0
TLS3_k127_1290649_38 Proteolipid membrane potential modulator - - - 0.00000000000004976 74.0
TLS3_k127_1290649_39 ATPases associated with a variety of cellular activities - - - 0.0000000000001494 81.0
TLS3_k127_1290649_4 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 427.0
TLS3_k127_1290649_40 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair - - - 0.0000000000002465 80.0
TLS3_k127_1290649_41 Protein of unknown function (DUF1761) - - - 0.0000000004359 68.0
TLS3_k127_1290649_42 (Hpt) domain - - - 0.00000001594 62.0
TLS3_k127_1290649_43 YHS domain protein - - - 0.00001141 57.0
TLS3_k127_1290649_44 RepB plasmid - - - 0.00001879 54.0
TLS3_k127_1290649_46 Terminase-like family - - - 0.0002397 54.0
TLS3_k127_1290649_5 IrrE N-terminal-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 394.0
TLS3_k127_1290649_6 Belongs to the arginase family K01476 - 3.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 387.0
TLS3_k127_1290649_7 glucose sorbosone K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 376.0
TLS3_k127_1290649_8 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 366.0
TLS3_k127_1290649_9 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 348.0
TLS3_k127_1712507_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1907.0
TLS3_k127_1712507_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1757.0
TLS3_k127_1712507_10 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 594.0
TLS3_k127_1712507_11 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 572.0
TLS3_k127_1712507_12 PFAM isocitrate lyase and phosphorylmutase K01637 - 4.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008341 563.0
TLS3_k127_1712507_13 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 548.0
TLS3_k127_1712507_14 Dihydroorotate dehydrogenase K17723 - 1.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 539.0
TLS3_k127_1712507_15 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 471.0
TLS3_k127_1712507_16 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 462.0
TLS3_k127_1712507_17 Heavy metal translocating P-type atpase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 453.0
TLS3_k127_1712507_18 Putative zinc-binding metallo-peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 424.0
TLS3_k127_1712507_19 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 437.0
TLS3_k127_1712507_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1312.0
TLS3_k127_1712507_20 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 406.0
TLS3_k127_1712507_21 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 403.0
TLS3_k127_1712507_22 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 396.0
TLS3_k127_1712507_23 Belongs to the GSP D family K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 403.0
TLS3_k127_1712507_24 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008323 376.0
TLS3_k127_1712507_25 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 371.0
TLS3_k127_1712507_26 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000547 351.0
TLS3_k127_1712507_27 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 335.0
TLS3_k127_1712507_28 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 309.0
TLS3_k127_1712507_29 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 310.0
TLS3_k127_1712507_3 Dehydrogenase E1 component K00164 - 1.2.4.2 9.648e-283 897.0
TLS3_k127_1712507_30 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 297.0
TLS3_k127_1712507_31 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004475 280.0
TLS3_k127_1712507_32 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000001316 250.0
TLS3_k127_1712507_33 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000517 245.0
TLS3_k127_1712507_34 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000003902 238.0
TLS3_k127_1712507_35 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000008198 236.0
TLS3_k127_1712507_36 Protein of unknown function (DUF2959) - - - 0.000000000000000000000000000000000000000000000000000000001493 207.0
TLS3_k127_1712507_37 cell envelope organization K05807,K08309 - - 0.0000000000000000000000000000000000000000000000000000004651 206.0
TLS3_k127_1712507_38 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000001043 208.0
TLS3_k127_1712507_39 ribosomal protein l10 K02864 - - 0.00000000000000000000000000000000000000000000000002533 186.0
TLS3_k127_1712507_4 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 2.017e-258 814.0
TLS3_k127_1712507_40 - - - - 0.00000000000000000000000000000000000000000000001724 179.0
TLS3_k127_1712507_41 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000622 172.0
TLS3_k127_1712507_42 isomerase - - - 0.0000000000000000000000000000000000000000000006147 177.0
TLS3_k127_1712507_43 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000005348 170.0
TLS3_k127_1712507_44 Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. TrmE GTPase family K03650 - - 0.0000000000000000000000000000000000000000006475 169.0
TLS3_k127_1712507_45 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000007489 158.0
TLS3_k127_1712507_46 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000001433 151.0
TLS3_k127_1712507_47 Methyltransferase domain - - - 0.000000000000000000000000000000000002575 147.0
TLS3_k127_1712507_48 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K04749 - - 0.0000000000000000000000000000000003242 136.0
TLS3_k127_1712507_49 AMP binding - - - 0.000000000000000000000000000000001835 141.0
TLS3_k127_1712507_5 Malate synthase K01638 - 2.3.3.9 1.512e-214 679.0
TLS3_k127_1712507_50 Wd40 repeat-containing protein - - - 0.000000000000000000000000000000005796 143.0
TLS3_k127_1712507_51 Regulatory protein, FmdB family - - - 0.0000000000000000000000000000001374 126.0
TLS3_k127_1712507_53 - - - - 0.0000000000000000000000000000002579 135.0
TLS3_k127_1712507_54 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase) K04757 - 2.7.11.1 0.0000000000000000000000000002505 120.0
TLS3_k127_1712507_55 Histone methylation protein DOT1 - - - 0.000000000000000000001388 106.0
TLS3_k127_1712507_56 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000002555 95.0
TLS3_k127_1712507_57 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000249 95.0
TLS3_k127_1712507_58 Subtilase family - - - 0.00000000000000002691 98.0
TLS3_k127_1712507_59 Lipopolysaccharide-assembly - - - 0.00000000000000006011 88.0
TLS3_k127_1712507_6 Aminotransferase class-III - - - 5.138e-196 622.0
TLS3_k127_1712507_60 LysM domain - - - 0.00000000000000006352 91.0
TLS3_k127_1712507_61 DUF167 K09131 - - 0.0000000000004212 74.0
TLS3_k127_1712507_62 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000006114 78.0
TLS3_k127_1712507_63 M6 family metalloprotease domain protein - - - 0.00000000007829 76.0
TLS3_k127_1712507_65 CsbD-like - - - 0.0000003612 55.0
TLS3_k127_1712507_66 PFAM Calcium calmodulin dependent protein kinase II association-domain protein - - - 0.0000009085 61.0
TLS3_k127_1712507_67 general secretion pathway protein K02456 - - 0.000001398 59.0
TLS3_k127_1712507_68 Heavy-metal-associated domain K07213 - - 0.000004978 53.0
TLS3_k127_1712507_69 Histidine kinase - - - 0.00001638 55.0
TLS3_k127_1712507_7 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 3.161e-195 638.0
TLS3_k127_1712507_70 of the drug metabolite transporter (DMT) superfamily - - - 0.0009014 46.0
TLS3_k127_1712507_8 Transporter K12942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 622.0
TLS3_k127_1712507_9 Amidohydrolase family K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 602.0
TLS3_k127_2043925_0 imidazolonepropionase activity K01443 - 3.5.1.25 1.684e-220 729.0
TLS3_k127_2043925_1 Protein tyrosine kinase K12132 - 2.7.11.1 7.488e-194 638.0
TLS3_k127_2043925_10 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006075 443.0
TLS3_k127_2043925_11 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 445.0
TLS3_k127_2043925_12 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 434.0
TLS3_k127_2043925_13 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 387.0
TLS3_k127_2043925_14 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 381.0
TLS3_k127_2043925_15 flagellar hook-associated protein 2 K02407 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 402.0
TLS3_k127_2043925_16 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 377.0
TLS3_k127_2043925_17 imidazolonepropionase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 342.0
TLS3_k127_2043925_18 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 342.0
TLS3_k127_2043925_19 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 310.0
TLS3_k127_2043925_2 Peptidase family M3 K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 563.0
TLS3_k127_2043925_20 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 299.0
TLS3_k127_2043925_21 PFAM Peptidase M16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 295.0
TLS3_k127_2043925_22 PFAM mce related protein K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007743 298.0
TLS3_k127_2043925_23 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826,K02619 - 2.6.1.42,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005347 282.0
TLS3_k127_2043925_24 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001379 286.0
TLS3_k127_2043925_25 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000002635 254.0
TLS3_k127_2043925_26 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000002482 252.0
TLS3_k127_2043925_27 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000002229 249.0
TLS3_k127_2043925_28 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000001921 237.0
TLS3_k127_2043925_29 of the beta-lactamase superfamily I K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000006225 235.0
TLS3_k127_2043925_3 oxidoreductase activity K02396 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 574.0
TLS3_k127_2043925_30 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000006256 238.0
TLS3_k127_2043925_31 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000001019 214.0
TLS3_k127_2043925_32 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000000000003671 208.0
TLS3_k127_2043925_33 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000004205 202.0
TLS3_k127_2043925_34 - - - - 0.00000000000000000000000000000000000000000000000000000107 208.0
TLS3_k127_2043925_35 Family of unknown function (DUF5309) - - - 0.0000000000000000000000000000000000000000000000000006039 198.0
TLS3_k127_2043925_36 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000005228 196.0
TLS3_k127_2043925_37 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000001101 192.0
TLS3_k127_2043925_38 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000002313 183.0
TLS3_k127_2043925_39 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000004638 184.0
TLS3_k127_2043925_4 COG1674 DNA segregation ATPase FtsK SpoIIIE and related K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 520.0
TLS3_k127_2043925_40 Gaf domain K08968 - 1.8.4.14 0.000000000000000000000000000000000000000000000005046 177.0
TLS3_k127_2043925_41 Psort location Cytoplasmic, score K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000001014 162.0
TLS3_k127_2043925_42 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000007931 158.0
TLS3_k127_2043925_43 paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000000000001293 153.0
TLS3_k127_2043925_44 thioesterase K07107 - - 0.00000000000000000000000000000000000005539 146.0
TLS3_k127_2043925_45 phospholipase C - - - 0.00000000000000000000000000000000002591 154.0
TLS3_k127_2043925_46 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.00000000000000000000000000000000002985 151.0
TLS3_k127_2043925_47 FHA domain K07315 - 3.1.3.3 0.0000000000000000000000000000003775 140.0
TLS3_k127_2043925_48 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000008341 126.0
TLS3_k127_2043925_49 Ion transport protein K10716 - - 0.000000000000000000000000008339 119.0
TLS3_k127_2043925_5 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 499.0
TLS3_k127_2043925_50 Histidine kinase - - - 0.00000000000000000000000001091 120.0
TLS3_k127_2043925_51 - - - - 0.0000000000000000000000002962 117.0
TLS3_k127_2043925_52 N-acetylmuramoyl-L-alanine amidase - - - 0.000000000000000000000001292 115.0
TLS3_k127_2043925_53 COG1516 Flagellin-specific chaperone FliS K02422 - - 0.0000000000000000000004579 103.0
TLS3_k127_2043925_54 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000003182 104.0
TLS3_k127_2043925_56 BFD-like [2Fe-2S] binding domain - - - 0.0000000000000000002874 93.0
TLS3_k127_2043925_58 Protein of unknown function DUF262 - - - 0.00000000000000001443 82.0
TLS3_k127_2043925_59 - - - - 0.0000000000000003113 85.0
TLS3_k127_2043925_6 His Kinase A (phosphoacceptor) domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 501.0
TLS3_k127_2043925_60 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07689 - - 0.0000000000000003652 88.0
TLS3_k127_2043925_61 SnoaL-like domain - - - 0.0000000000000004531 87.0
TLS3_k127_2043925_62 UPF0391 membrane protein - - - 0.000000000000001327 79.0
TLS3_k127_2043925_63 Pkd domain containing protein - - - 0.0000000000006725 82.0
TLS3_k127_2043925_65 - - - - 0.0000000002477 63.0
TLS3_k127_2043925_66 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.0000002343 60.0
TLS3_k127_2043925_68 Flagellar protein YcgR - - - 0.00002301 53.0
TLS3_k127_2043925_7 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 482.0
TLS3_k127_2043925_70 PFAM Anti-sigma-28 factor FlgM K02398 - - 0.0001155 49.0
TLS3_k127_2043925_71 Phage portal protein, SPP1 Gp6-like - - - 0.0001567 54.0
TLS3_k127_2043925_8 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 471.0
TLS3_k127_2043925_9 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 467.0
TLS3_k127_2290206_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 8.501e-255 796.0
TLS3_k127_2290206_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.848e-227 721.0
TLS3_k127_2290206_10 DNA polymerase K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 477.0
TLS3_k127_2290206_11 aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 448.0
TLS3_k127_2290206_12 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 428.0
TLS3_k127_2290206_13 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 436.0
TLS3_k127_2290206_14 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 427.0
TLS3_k127_2290206_15 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 418.0
TLS3_k127_2290206_16 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 389.0
TLS3_k127_2290206_17 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 382.0
TLS3_k127_2290206_18 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 374.0
TLS3_k127_2290206_19 Saccharopine dehydrogenase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 353.0
TLS3_k127_2290206_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K12257 - - 2.615e-206 684.0
TLS3_k127_2290206_20 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 350.0
TLS3_k127_2290206_21 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K00627 - 1.2.4.1,2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 349.0
TLS3_k127_2290206_22 transferase K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009053 332.0
TLS3_k127_2290206_23 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 309.0
TLS3_k127_2290206_24 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 301.0
TLS3_k127_2290206_25 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008901 274.0
TLS3_k127_2290206_26 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003423 276.0
TLS3_k127_2290206_27 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001354 272.0
TLS3_k127_2290206_28 Ribosomal protein S1 K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003876 278.0
TLS3_k127_2290206_29 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000466 281.0
TLS3_k127_2290206_3 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 593.0
TLS3_k127_2290206_30 Bacterial Peptidase A24 N-terminal domain K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000302 270.0
TLS3_k127_2290206_31 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000003345 261.0
TLS3_k127_2290206_32 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001431 256.0
TLS3_k127_2290206_33 PFAM FAD dependent oxidoreductase K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000003299 254.0
TLS3_k127_2290206_34 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000005029 250.0
TLS3_k127_2290206_35 Endonuclease/Exonuclease/phosphatase family K07004 - - 0.000000000000000000000000000000000000000000000000000000000000001593 246.0
TLS3_k127_2290206_36 histidyl-tRNA synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000002909 225.0
TLS3_k127_2290206_37 COG0402 Cytosine deaminase and related metal-dependent K20810 - 3.5.4.40 0.00000000000000000000000000000000000000000000000000000000004037 222.0
TLS3_k127_2290206_38 domain, Protein K07004 - - 0.000000000000000000000000000000000000000000000000000001782 218.0
TLS3_k127_2290206_39 - - - - 0.000000000000000000000000000000000000000000000000000001815 210.0
TLS3_k127_2290206_4 Fumarylacetoacetate (FAA) hydrolase K01555 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 543.0
TLS3_k127_2290206_40 permease K03548 - - 0.00000000000000000000000000000000000000000000000000367 198.0
TLS3_k127_2290206_41 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000006186 185.0
TLS3_k127_2290206_42 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000005458 195.0
TLS3_k127_2290206_43 COG NOG14600 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000000003892 174.0
TLS3_k127_2290206_44 - - - - 0.000000000000000000000000000000000000000000000412 189.0
TLS3_k127_2290206_45 Methylpurine-DNA glycosylase (MPG) K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.0000000000000000000000000000000000000000001405 169.0
TLS3_k127_2290206_46 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000139 164.0
TLS3_k127_2290206_47 Lysine methyltransferase - - - 0.000000000000000000000000000000000000001067 158.0
TLS3_k127_2290206_48 PFAM Rhomboid family - - - 0.000000000000000000000000000000000000001089 161.0
TLS3_k127_2290206_49 Flagellar motor protein K02557 - - 0.000000000000000000000000000000000000113 154.0
TLS3_k127_2290206_5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 552.0
TLS3_k127_2290206_50 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000001681 143.0
TLS3_k127_2290206_51 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000000000007634 136.0
TLS3_k127_2290206_52 PFAM Peptidase family M50 - - - 0.0000000000000000000000000000000001336 148.0
TLS3_k127_2290206_53 - - - - 0.000000000000000000000000000001674 125.0
TLS3_k127_2290206_54 CAAX protease self-immunity - - - 0.00000000000000000000000000001527 128.0
TLS3_k127_2290206_55 DNA-binding transcription factor activity - - - 0.000000000000000000000000002688 115.0
TLS3_k127_2290206_56 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000004429 125.0
TLS3_k127_2290206_57 COG NOG15344 non supervised orthologous group - - - 0.0000000000000000000000003291 106.0
TLS3_k127_2290206_58 General stress protein K06884 - - 0.0000000000000000000000006439 107.0
TLS3_k127_2290206_59 - - - - 0.000000000000000000000004034 114.0
TLS3_k127_2290206_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 526.0
TLS3_k127_2290206_60 positive regulation of growth rate - - - 0.0000000000000000000007349 105.0
TLS3_k127_2290206_61 - - - - 0.000000000000000001625 96.0
TLS3_k127_2290206_63 - - - - 0.000000000000000156 91.0
TLS3_k127_2290206_64 - - - - 0.000000000000002502 78.0
TLS3_k127_2290206_65 OmpA family - - - 0.000000000000004217 83.0
TLS3_k127_2290206_66 pilus assembly protein K02662 - - 0.00000000000009046 85.0
TLS3_k127_2290206_67 Predicted membrane protein (DUF2339) - - - 0.0000000000001467 85.0
TLS3_k127_2290206_68 protein transport K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000002477 76.0
TLS3_k127_2290206_69 Tetratricopeptide repeat - - - 0.000000000151 74.0
TLS3_k127_2290206_7 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 512.0
TLS3_k127_2290206_71 - - - - 0.000000001079 63.0
TLS3_k127_2290206_72 Binds directly to 16S ribosomal RNA K02968 - - 0.000000003527 61.0
TLS3_k127_2290206_73 Transglutaminase/protease-like homologues - - - 0.000000004742 68.0
TLS3_k127_2290206_74 the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts - - - 0.000000006023 57.0
TLS3_k127_2290206_75 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000008641 62.0
TLS3_k127_2290206_76 - - - - 0.00000003088 57.0
TLS3_k127_2290206_77 MlaD protein K02067 - - 0.00000003473 65.0
TLS3_k127_2290206_78 - - - - 0.00000008619 54.0
TLS3_k127_2290206_8 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009111 497.0
TLS3_k127_2290206_80 DinB superfamily K07552 - - 0.000000286 59.0
TLS3_k127_2290206_81 Putative prokaryotic signal transducing protein - - - 0.0000003597 60.0
TLS3_k127_2290206_82 - - - - 0.000002807 51.0
TLS3_k127_2290206_83 PFAM SMP-30 Gluconolaconase - - - 0.000003125 59.0
TLS3_k127_2290206_84 - - - - 0.00001872 47.0
TLS3_k127_2290206_85 NUDIX domain - - - 0.00005664 53.0
TLS3_k127_2290206_86 - - - - 0.00007796 47.0
TLS3_k127_2290206_87 DNA integration - - - 0.0001071 44.0
TLS3_k127_2290206_89 Fibronectin type III domain protein - - - 0.0006708 53.0
TLS3_k127_2290206_9 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 472.0
TLS3_k127_2290206_90 Metallo-peptidase family M12B Reprolysin-like - - - 0.0008782 53.0
TLS3_k127_2433142_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1097.0
TLS3_k127_2433142_1 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 8.457e-283 880.0
TLS3_k127_2433142_10 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 430.0
TLS3_k127_2433142_11 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 411.0
TLS3_k127_2433142_12 Zinc carboxypeptidase K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 398.0
TLS3_k127_2433142_13 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 383.0
TLS3_k127_2433142_14 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008474 386.0
TLS3_k127_2433142_15 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 357.0
TLS3_k127_2433142_16 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 348.0
TLS3_k127_2433142_17 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 363.0
TLS3_k127_2433142_18 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 330.0
TLS3_k127_2433142_19 COG1398 Fatty-acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 327.0
TLS3_k127_2433142_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.355e-224 714.0
TLS3_k127_2433142_20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 338.0
TLS3_k127_2433142_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005421 334.0
TLS3_k127_2433142_22 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 318.0
TLS3_k127_2433142_23 ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001093 286.0
TLS3_k127_2433142_24 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000002425 257.0
TLS3_k127_2433142_25 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000006992 248.0
TLS3_k127_2433142_26 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000483 244.0
TLS3_k127_2433142_27 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000001097 245.0
TLS3_k127_2433142_28 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000001589 235.0
TLS3_k127_2433142_29 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000001119 231.0
TLS3_k127_2433142_3 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.483e-206 677.0
TLS3_k127_2433142_30 DNA methylase K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000005345 211.0
TLS3_k127_2433142_31 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000002397 226.0
TLS3_k127_2433142_32 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000195 210.0
TLS3_k127_2433142_33 Sugar nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000006492 209.0
TLS3_k127_2433142_34 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000007008 201.0
TLS3_k127_2433142_35 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000005113 198.0
TLS3_k127_2433142_36 Prolyl oligopeptidase family K06889 - - 0.00000000000000000000000000000000000000000000002245 182.0
TLS3_k127_2433142_37 Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source K01483 GO:0003674,GO:0003824,GO:0016829,GO:0016840,GO:0016842,GO:0050385 4.3.2.3 0.000000000000000000000000000000000000000000004172 168.0
TLS3_k127_2433142_38 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - - 0.000000000000000000000000000000000000000001329 164.0
TLS3_k127_2433142_39 cell redox homeostasis K03671,K07152 - - 0.0000000000000000000000000000000000000009494 161.0
TLS3_k127_2433142_4 DEAD DEAH box helicase K03654 - 3.6.4.12 2.651e-204 659.0
TLS3_k127_2433142_40 protein conserved in bacteria - - - 0.00000000000000000000000000000000000003546 149.0
TLS3_k127_2433142_41 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000001294 136.0
TLS3_k127_2433142_42 CoA-binding protein K06929 - - 0.0000000000000000000000000004019 117.0
TLS3_k127_2433142_44 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000001784 95.0
TLS3_k127_2433142_45 Hep Hag repeat protein - - - 0.0000000000000000004159 102.0
TLS3_k127_2433142_46 deoxyhypusine monooxygenase activity - - - 0.000000000000000001006 99.0
TLS3_k127_2433142_47 - - - - 0.000000000000000003815 92.0
TLS3_k127_2433142_49 Dicarboxylate transport - - - 0.0000000000000001605 94.0
TLS3_k127_2433142_5 Alcohol dehydrogenase GroES domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 608.0
TLS3_k127_2433142_50 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000003389 84.0
TLS3_k127_2433142_51 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000005106 77.0
TLS3_k127_2433142_52 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.0000000007108 72.0
TLS3_k127_2433142_54 - - - - 0.000000003109 62.0
TLS3_k127_2433142_55 general secretion pathway protein - - - 0.00000000485 68.0
TLS3_k127_2433142_56 GGDEF domain K02657,K03413,K03415,K11522 - - 0.00000158 58.0
TLS3_k127_2433142_57 - - - - 0.00001064 57.0
TLS3_k127_2433142_58 general secretion pathway protein G K02456 - - 0.00001118 58.0
TLS3_k127_2433142_59 Protein of unknown function (DUF1318) - - - 0.00004244 54.0
TLS3_k127_2433142_6 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 601.0
TLS3_k127_2433142_60 - - - - 0.0000644 49.0
TLS3_k127_2433142_61 - - - - 0.0001651 44.0
TLS3_k127_2433142_62 TIGRFAM outer membrane autotransporter barrel domain - - - 0.0002329 54.0
TLS3_k127_2433142_7 COG1077 Actin-like ATPase involved in cell morphogenesis K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009143 569.0
TLS3_k127_2433142_8 PFAM OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 517.0
TLS3_k127_2433142_9 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 508.0
TLS3_k127_2459292_0 protoporphyrinogen oxidase activity K01854,K07011 - 5.4.99.9 0.0 1067.0
TLS3_k127_2459292_1 Glycosyl hydrolases family 15 K01087 - 3.1.3.12 1.942e-285 900.0
TLS3_k127_2459292_10 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 608.0
TLS3_k127_2459292_11 COG3104 Dipeptide tripeptide permease K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 560.0
TLS3_k127_2459292_12 helicase K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 571.0
TLS3_k127_2459292_13 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 556.0
TLS3_k127_2459292_14 COG1115 Na alanine symporter K03310 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008119 561.0
TLS3_k127_2459292_15 Kynurenine--oxoglutarate transaminase - GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0008483,GO:0010326,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 541.0
TLS3_k127_2459292_16 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 550.0
TLS3_k127_2459292_17 serine-type peptidase activity K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005929 551.0
TLS3_k127_2459292_18 Glycosyltransferase family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 511.0
TLS3_k127_2459292_19 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 503.0
TLS3_k127_2459292_2 Belongs to the glycosyl hydrolase 2 family - - - 1.856e-263 825.0
TLS3_k127_2459292_20 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 470.0
TLS3_k127_2459292_21 pyruvate kinase activity K00873 GO:0000003,GO:0000287,GO:0003006,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006629,GO:0006631,GO:0006633,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009791,GO:0009987,GO:0010035,GO:0010038,GO:0010154,GO:0010431,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0021700,GO:0022414,GO:0030955,GO:0031420,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046686,GO:0046700,GO:0046872,GO:0046939,GO:0048316,GO:0048608,GO:0048609,GO:0048731,GO:0048856,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0061458,GO:0071695,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 439.0
TLS3_k127_2459292_22 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008976 437.0
TLS3_k127_2459292_23 COG0038 Chloride channel protein EriC K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 427.0
TLS3_k127_2459292_24 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007196 422.0
TLS3_k127_2459292_25 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 383.0
TLS3_k127_2459292_26 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 392.0
TLS3_k127_2459292_27 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 384.0
TLS3_k127_2459292_28 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 388.0
TLS3_k127_2459292_29 PFAM PfkB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 339.0
TLS3_k127_2459292_3 elongation factor G K02355 - - 2.529e-225 717.0
TLS3_k127_2459292_30 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 340.0
TLS3_k127_2459292_31 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 345.0
TLS3_k127_2459292_32 Penicillin binding protein transpeptidase domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 342.0
TLS3_k127_2459292_33 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 315.0
TLS3_k127_2459292_34 transmembrane transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 308.0
TLS3_k127_2459292_35 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 307.0
TLS3_k127_2459292_36 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 294.0
TLS3_k127_2459292_37 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 288.0
TLS3_k127_2459292_38 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000103 272.0
TLS3_k127_2459292_39 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000002559 278.0
TLS3_k127_2459292_4 FAD linked oxidases, C-terminal domain - - - 8.95e-224 728.0
TLS3_k127_2459292_40 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002928 282.0
TLS3_k127_2459292_41 general secretion pathway protein D K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001996 291.0
TLS3_k127_2459292_42 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000004081 283.0
TLS3_k127_2459292_43 Belongs to the CinA family K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000008581 276.0
TLS3_k127_2459292_44 Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009893,GO:0009987,GO:0019216,GO:0019222,GO:0019747,GO:0031323,GO:0031325,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045828,GO:0045834,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:0080090,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000097 257.0
TLS3_k127_2459292_45 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000007568 260.0
TLS3_k127_2459292_46 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000515 248.0
TLS3_k127_2459292_47 TIM-barrel fold K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000008138 245.0
TLS3_k127_2459292_48 Type 4 fimbrial assembly protein pilC K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000001148 241.0
TLS3_k127_2459292_49 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000001993 220.0
TLS3_k127_2459292_5 Citrate transporter - - - 9.216e-215 682.0
TLS3_k127_2459292_50 Endoribonuclease L-PSP K15067 - 3.5.99.5 0.00000000000000000000000000000000000000000000000000000001885 199.0
TLS3_k127_2459292_51 Zn-dependent protease contains TPR repeats - - - 0.000000000000000000000000000000000000000000000000004281 193.0
TLS3_k127_2459292_52 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000145 186.0
TLS3_k127_2459292_53 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000001878 178.0
TLS3_k127_2459292_55 Tyrosine phosphatase family - - - 0.000000000000000000000000000000000000000000002231 178.0
TLS3_k127_2459292_56 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000978 179.0
TLS3_k127_2459292_57 - - - - 0.0000000000000000000000000000000000000000000433 170.0
TLS3_k127_2459292_58 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000002199 165.0
TLS3_k127_2459292_59 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.0000000000000000000000000000000000000001429 157.0
TLS3_k127_2459292_6 Belongs to the aldehyde dehydrogenase family K00128,K00130,K10217 - 1.2.1.3,1.2.1.32,1.2.1.8,1.2.1.85 2.061e-205 649.0
TLS3_k127_2459292_61 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000004254 151.0
TLS3_k127_2459292_62 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000001322 166.0
TLS3_k127_2459292_63 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000005856 149.0
TLS3_k127_2459292_64 COG4747 ACT domain-containing protein - - - 0.00000000000000000000000000000000003596 140.0
TLS3_k127_2459292_65 Belongs to the bacterial histone-like protein family - - - 0.0000000000000000000000000000005818 125.0
TLS3_k127_2459292_66 - - - - 0.000000000000000000000000000001995 128.0
TLS3_k127_2459292_67 Type II secretion system (T2SS), protein K - - - 0.0000000000000000000000000002504 130.0
TLS3_k127_2459292_68 Type II secretion system (T2SS), protein G K02456 - - 0.00000000000000000000000001274 115.0
TLS3_k127_2459292_69 small membrane protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000001857 113.0
TLS3_k127_2459292_7 Anthranilate synthase K01657 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009507,GO:0009536,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 616.0
TLS3_k127_2459292_70 Helix-turn-helix domain K03088 - - 0.0000000000000000000000008018 111.0
TLS3_k127_2459292_71 Could be involved in insertion of integral membrane proteins into the membrane K08998 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.000000000000000000000001331 107.0
TLS3_k127_2459292_72 Thioredoxin-like - - - 0.0000000000000000000006741 109.0
TLS3_k127_2459292_73 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000008188 100.0
TLS3_k127_2459292_74 domain protein K14274 - - 0.00000000000000000001017 109.0
TLS3_k127_2459292_75 CYTH K01768,K05873 - 4.6.1.1 0.00000000000000000006699 96.0
TLS3_k127_2459292_77 Ferric uptake regulator family K09825 - - 0.00000000000000001466 88.0
TLS3_k127_2459292_79 - - - - 0.000000000000001396 85.0
TLS3_k127_2459292_8 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 590.0
TLS3_k127_2459292_80 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000001979 81.0
TLS3_k127_2459292_81 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.00000000000001469 87.0
TLS3_k127_2459292_82 Iron sulfur-containing domain, CDGSH-type - - - 0.0000000000000307 76.0
TLS3_k127_2459292_83 - - - - 0.00000000000009328 81.0
TLS3_k127_2459292_84 - - - - 0.0000000000005246 72.0
TLS3_k127_2459292_85 Thiamine biosynthesis protein K03154 - - 0.000000000001018 71.0
TLS3_k127_2459292_86 PFAM Formiminotransferase-cyclodeaminase - - - 0.0000000000242 72.0
TLS3_k127_2459292_87 COG COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog K03088 - - 0.000000001274 68.0
TLS3_k127_2459292_88 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.00000000947 67.0
TLS3_k127_2459292_9 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009174 593.0
TLS3_k127_2459292_91 DNA-directed RNA polymerase specialized sigma subunit sigma24 K03088 - - 0.00001833 55.0
TLS3_k127_2459292_92 general secretion pathway protein K02456 - - 0.00002471 55.0
TLS3_k127_2459292_93 conserved protein (DUF2203) - - - 0.0002443 51.0
TLS3_k127_2459292_94 type IV pilus modification protein PilV K02671 - - 0.0004444 50.0
TLS3_k127_301317_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005593 286.0
TLS3_k127_301317_1 DNA methylase - - - 0.0000000000000000000000000000000000000000000000000004211 187.0
TLS3_k127_301317_2 beta-lactamase - - - 0.000000000000000000000000000000000000000000003789 178.0
TLS3_k127_301317_3 - - - - 0.00000003319 66.0
TLS3_k127_3277996_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 8.228e-284 911.0
TLS3_k127_3277996_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 517.0
TLS3_k127_3277996_10 - - - - 0.0000000000000000000000000001133 129.0
TLS3_k127_3277996_11 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000002792 85.0
TLS3_k127_3277996_12 TIGRFAM outer membrane autotransporter barrel domain protein K15125 GO:0005575,GO:0005623,GO:0009986,GO:0044464 - 0.000000000000007947 90.0
TLS3_k127_3277996_2 transporter K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 484.0
TLS3_k127_3277996_3 PFAM Metal-dependent phosphohydrolase, HD K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 374.0
TLS3_k127_3277996_4 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000006453 262.0
TLS3_k127_3277996_5 COG1194 A G-specific DNA glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000002126 248.0
TLS3_k127_3277996_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000001301 215.0
TLS3_k127_3277996_7 DNA methylase - - - 0.000000000000000000000000000000000000000000000000003504 184.0
TLS3_k127_3277996_8 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000001115 168.0
TLS3_k127_3277996_9 ROK family K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 0.00000000000000000000000000000000000000000001191 177.0
TLS3_k127_346453_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1273.0
TLS3_k127_346453_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 1.579e-240 757.0
TLS3_k127_346453_10 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 481.0
TLS3_k127_346453_11 COG1055 Na H antiporter NhaD and related arsenite - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 462.0
TLS3_k127_346453_12 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 394.0
TLS3_k127_346453_13 -O-antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 398.0
TLS3_k127_346453_14 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 385.0
TLS3_k127_346453_15 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 379.0
TLS3_k127_346453_16 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 391.0
TLS3_k127_346453_17 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 362.0
TLS3_k127_346453_18 ABC-type multidrug transport system ATPase K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 356.0
TLS3_k127_346453_19 PFAM glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 344.0
TLS3_k127_346453_2 Belongs to the aldehyde dehydrogenase family K00128,K06447 - 1.2.1.3,1.2.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 591.0
TLS3_k127_346453_20 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 339.0
TLS3_k127_346453_21 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 342.0
TLS3_k127_346453_22 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 329.0
TLS3_k127_346453_23 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 324.0
TLS3_k127_346453_24 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 304.0
TLS3_k127_346453_25 protein transport across the cell outer membrane K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001985 292.0
TLS3_k127_346453_26 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001219 296.0
TLS3_k127_346453_27 tail specific protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003265 270.0
TLS3_k127_346453_28 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000003216 229.0
TLS3_k127_346453_29 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000006033 224.0
TLS3_k127_346453_3 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 583.0
TLS3_k127_346453_30 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000018 228.0
TLS3_k127_346453_31 protein histidine kinase activity K07636,K07768,K11383 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000005688 226.0
TLS3_k127_346453_32 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.0000000000000000000000000000000000000000000000000000001894 218.0
TLS3_k127_346453_33 - K01992 - - 0.0000000000000000000000000000000000000000000000000005361 207.0
TLS3_k127_346453_34 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.000000000000000000000000000000000000000000000000001315 197.0
TLS3_k127_346453_35 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000005203 185.0
TLS3_k127_346453_37 synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000006759 166.0
TLS3_k127_346453_38 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000001934 175.0
TLS3_k127_346453_39 Oligosaccharide biosynthesis protein Alg14 like - - - 0.0000000000000000000000000000000000000000006556 162.0
TLS3_k127_346453_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 559.0
TLS3_k127_346453_40 Alcohol dehydrogenase GroES domain protein K00001 - 1.1.1.1 0.000000000000000000000000000000000000000007942 166.0
TLS3_k127_346453_41 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000005541 154.0
TLS3_k127_346453_42 Protein involved in cellulose biosynthesis - - - 0.000000000000000000000000000000000000003237 161.0
TLS3_k127_346453_43 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000003709 163.0
TLS3_k127_346453_44 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000004351 149.0
TLS3_k127_346453_45 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000005499 136.0
TLS3_k127_346453_46 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000008251 144.0
TLS3_k127_346453_47 Protein involved in cellulose biosynthesis - - - 0.00000000000000000000000000002172 131.0
TLS3_k127_346453_48 Histone methylation protein DOT1 - - - 0.000000000000000000000000006299 121.0
TLS3_k127_346453_49 Polysaccharide deacetylase - - - 0.00000000000000000000000003472 118.0
TLS3_k127_346453_5 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 539.0
TLS3_k127_346453_50 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000003184 114.0
TLS3_k127_346453_52 Extracellular repeat protein, HAF family - - - 0.0000000000000000009741 99.0
TLS3_k127_346453_53 deoxyhypusine monooxygenase activity - - - 0.000000000000000003572 95.0
TLS3_k127_346453_54 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000002315 86.0
TLS3_k127_346453_55 - - - - 0.0000000000000002848 79.0
TLS3_k127_346453_56 - - - - 0.00000000000000308 79.0
TLS3_k127_346453_57 cellulase activity - - - 0.00000000000001768 88.0
TLS3_k127_346453_58 Transcriptional regulator PadR-like family - - - 0.0000000000003417 77.0
TLS3_k127_346453_59 - - - - 0.0000000000008375 69.0
TLS3_k127_346453_6 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 518.0
TLS3_k127_346453_60 - - - - 0.000000000007609 75.0
TLS3_k127_346453_61 - - - - 0.00000000002238 65.0
TLS3_k127_346453_62 Pfam:N_methyl_2 K02456 - - 0.00000000006495 70.0
TLS3_k127_346453_63 - - - - 0.000000009491 58.0
TLS3_k127_346453_65 HflC and HflK could regulate a protease K04087 - - 0.00000002748 65.0
TLS3_k127_346453_66 prohibitin homologues K04088 - - 0.0000002266 63.0
TLS3_k127_346453_67 - - - - 0.0000003269 53.0
TLS3_k127_346453_68 Yip1 domain - - - 0.000004747 59.0
TLS3_k127_346453_69 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000768 53.0
TLS3_k127_346453_7 Type II secretory pathway component PulF K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 514.0
TLS3_k127_346453_70 - - - - 0.00001036 48.0
TLS3_k127_346453_71 pilus assembly protein PilM K02662 - - 0.0000179 57.0
TLS3_k127_346453_72 Prepilin-type N-terminal cleavage methylation domain K10927 - - 0.00001999 53.0
TLS3_k127_346453_73 Prokaryotic N-terminal methylation motif - - - 0.0007565 51.0
TLS3_k127_346453_8 PFAM Type II secretion system protein E K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 500.0
TLS3_k127_346453_9 COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 473.0
TLS3_k127_4124619_0 type II secretion system protein E K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 504.0
TLS3_k127_4124619_1 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 386.0
TLS3_k127_4124619_10 PFAM TadE family protein - - - 0.00000000000008096 84.0
TLS3_k127_4124619_11 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000001451 74.0
TLS3_k127_4124619_12 PFAM Peptidase A24A, prepilin type IV K02278 - 3.4.23.43 0.00000000001643 72.0
TLS3_k127_4124619_13 SAF K02279 - - 0.0000000001599 72.0
TLS3_k127_4124619_14 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000003467 63.0
TLS3_k127_4124619_15 PFAM Flp Fap pilin component K02651 - - 0.0000000408 59.0
TLS3_k127_4124619_16 TadE-like protein - - - 0.000002143 57.0
TLS3_k127_4124619_17 Tetratricopeptide repeat - - - 0.000004922 57.0
TLS3_k127_4124619_2 Pilus formation protein N terminal region K02280 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000437 298.0
TLS3_k127_4124619_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001227 302.0
TLS3_k127_4124619_4 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000001408 227.0
TLS3_k127_4124619_5 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000004191 190.0
TLS3_k127_4124619_6 Type II secretion system K12511 - - 0.0000000000000000000000000000000000000000001976 169.0
TLS3_k127_4124619_7 Phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000001654 161.0
TLS3_k127_4124619_8 Type II secretion system K12510 - - 0.0000000000000000000000000227 121.0
TLS3_k127_4124619_9 AAA domain K02282 - - 0.0000000000000000000005442 109.0
TLS3_k127_4246417_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.778e-257 802.0
TLS3_k127_4246417_1 von Willebrand factor, type A - - - 9.413e-240 761.0
TLS3_k127_4246417_10 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001672 286.0
TLS3_k127_4246417_11 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002387 267.0
TLS3_k127_4246417_12 Belongs to the MtfA family K09933 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006508,GO:0006807,GO:0008134,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009889,GO:0010468,GO:0010556,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0043170,GO:0043433,GO:0044092,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0051090,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0065009,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000001508 228.0
TLS3_k127_4246417_13 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000000000000000007615 220.0
TLS3_k127_4246417_14 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.00000000000000000000000000000000000000000000000000000000005688 212.0
TLS3_k127_4246417_15 of cations and cationic drugs K11741 - - 0.0000000000000000000000000000000000225 139.0
TLS3_k127_4246417_16 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000004376 127.0
TLS3_k127_4246417_17 - - - - 0.000000000000000000000000000168 126.0
TLS3_k127_4246417_18 Domain of unknown function (DUF1844) - - - 0.0000000000000000000000000001687 121.0
TLS3_k127_4246417_2 PFAM tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 1.216e-239 759.0
TLS3_k127_4246417_20 peptidyl-prolyl cis-trans isomerase activity - - - 0.00000000000000000000000002798 123.0
TLS3_k127_4246417_21 Belongs to the UPF0102 family K07460 - - 0.000000000000000001456 91.0
TLS3_k127_4246417_22 phosphorelay signal transduction system - - - 0.0000000000000001084 87.0
TLS3_k127_4246417_24 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000001666 79.0
TLS3_k127_4246417_25 HAF family - - - 0.000000000000009268 87.0
TLS3_k127_4246417_26 Protein involved in meta-pathway of phenol degradation - - - 0.000000000003495 76.0
TLS3_k127_4246417_27 - - - - 0.0000000002624 66.0
TLS3_k127_4246417_29 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000004029 64.0
TLS3_k127_4246417_3 Amidophosphoribosyltransferase K00764 - 2.4.2.14 1.761e-201 648.0
TLS3_k127_4246417_31 Heavy-metal-associated domain - - - 0.0000004235 57.0
TLS3_k127_4246417_4 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 456.0
TLS3_k127_4246417_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 441.0
TLS3_k127_4246417_6 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 445.0
TLS3_k127_4246417_7 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 342.0
TLS3_k127_4246417_8 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 312.0
TLS3_k127_4246417_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 286.0
TLS3_k127_4248967_0 PFAM Catalase K03781 - 1.11.1.6 6.252e-290 907.0
TLS3_k127_4248967_1 Heat shock 70 kDa protein K04043 - - 2.601e-283 882.0
TLS3_k127_4248967_10 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 627.0
TLS3_k127_4248967_100 AntiSigma factor K03088 - - 0.0000263 52.0
TLS3_k127_4248967_101 PFAM TPR repeat-containing protein - - - 0.0006812 52.0
TLS3_k127_4248967_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 612.0
TLS3_k127_4248967_12 Peptidase C1-like family K01372 - 3.4.22.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 604.0
TLS3_k127_4248967_13 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 597.0
TLS3_k127_4248967_14 COG0668 Small-conductance mechanosensitive channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 596.0
TLS3_k127_4248967_15 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007971 556.0
TLS3_k127_4248967_16 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 518.0
TLS3_k127_4248967_17 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 528.0
TLS3_k127_4248967_18 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 473.0
TLS3_k127_4248967_19 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 454.0
TLS3_k127_4248967_2 ABC-type transport system involved in Fe-S cluster assembly, permease component K09014 - - 1.154e-268 831.0
TLS3_k127_4248967_20 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 454.0
TLS3_k127_4248967_21 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 445.0
TLS3_k127_4248967_22 Belongs to the GSP D family K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 456.0
TLS3_k127_4248967_23 Tetratricopeptide repeat K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 457.0
TLS3_k127_4248967_24 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 425.0
TLS3_k127_4248967_25 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 423.0
TLS3_k127_4248967_26 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 385.0
TLS3_k127_4248967_27 COG0665 Glycine D-amino acid oxidases (deaminating) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 364.0
TLS3_k127_4248967_28 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 362.0
TLS3_k127_4248967_29 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 353.0
TLS3_k127_4248967_3 Molybdopterin oxidoreductase, iron-sulfur binding subunit K00184 - - 5.783e-265 853.0
TLS3_k127_4248967_30 PFAM NAD-dependent epimerase dehydratase K01784,K10011,K12449 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 332.0
TLS3_k127_4248967_31 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 326.0
TLS3_k127_4248967_32 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 312.0
TLS3_k127_4248967_33 Protein of unknown function (DUF4038) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 309.0
TLS3_k127_4248967_34 ABC transporter K10112,K11072,K17324 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 301.0
TLS3_k127_4248967_35 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 316.0
TLS3_k127_4248967_36 Capsular exopolysaccharide family K16554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003857 303.0
TLS3_k127_4248967_37 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004382 296.0
TLS3_k127_4248967_38 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009688 285.0
TLS3_k127_4248967_39 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004521 276.0
TLS3_k127_4248967_4 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.697e-243 764.0
TLS3_k127_4248967_40 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005784 270.0
TLS3_k127_4248967_41 polysaccharide export K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002247 280.0
TLS3_k127_4248967_42 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000003598 267.0
TLS3_k127_4248967_43 UDP-N-acetylmuramyl pentapeptide K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000004632 275.0
TLS3_k127_4248967_44 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000002379 274.0
TLS3_k127_4248967_45 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006945 269.0
TLS3_k127_4248967_46 COGs COG0491 Zn-dependent hydrolase including glyoxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002098 261.0
TLS3_k127_4248967_47 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002696 264.0
TLS3_k127_4248967_48 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002108 279.0
TLS3_k127_4248967_49 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002449 246.0
TLS3_k127_4248967_5 Polysulphide reductase K00185 - - 1.044e-229 719.0
TLS3_k127_4248967_50 Heme copper-type cytochrome quinol oxidase, subunit K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000003146 233.0
TLS3_k127_4248967_51 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005666 226.0
TLS3_k127_4248967_52 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000005829 231.0
TLS3_k127_4248967_53 signal sequence binding K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000008536 229.0
TLS3_k127_4248967_54 COG0084 Mg-dependent DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000003197 214.0
TLS3_k127_4248967_55 mercury ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000002712 213.0
TLS3_k127_4248967_56 DinB family - - - 0.000000000000000000000000000000000000000000000000000000118 199.0
TLS3_k127_4248967_57 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000001535 214.0
TLS3_k127_4248967_58 COG3001 Fructosamine-3-kinase - GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 - 0.0000000000000000000000000000000000000000000000000008649 194.0
TLS3_k127_4248967_59 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000589 187.0
TLS3_k127_4248967_6 Tetratricopeptide repeat - - - 4.615e-213 677.0
TLS3_k127_4248967_60 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000006467 190.0
TLS3_k127_4248967_61 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000118 184.0
TLS3_k127_4248967_62 COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog - - - 0.00000000000000000000000000000000000000000002161 168.0
TLS3_k127_4248967_63 Low molecular weight phosphotyrosine protein phosphatase K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000002402 163.0
TLS3_k127_4248967_64 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000436 160.0
TLS3_k127_4248967_65 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03325,K03741,K03892,K18701 - 1.20.4.1,2.8.4.2,3.1.3.48 0.000000000000000000000000000000000000000008187 173.0
TLS3_k127_4248967_66 pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000001031 169.0
TLS3_k127_4248967_67 Domain of unknown function (DUF2703) - - - 0.000000000000000000000000000000000000001358 155.0
TLS3_k127_4248967_68 Multisubunit Na H antiporter MnhE subunit K05562,K05569 - - 0.000000000000000000000000000000000000003053 151.0
TLS3_k127_4248967_69 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.00000000000000000000000000000000000001641 150.0
TLS3_k127_4248967_7 protein synonym multiple resistance and pH homeostasis protein A K05565 - - 1.63e-206 668.0
TLS3_k127_4248967_70 protein required for cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000000000000007168 158.0
TLS3_k127_4248967_71 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.0000000000000000000000000000000000002706 143.0
TLS3_k127_4248967_72 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000005374 143.0
TLS3_k127_4248967_73 Fe-S metabolism associated domain K02426 - - 0.0000000000000000000000000000000006554 136.0
TLS3_k127_4248967_74 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000001145 141.0
TLS3_k127_4248967_75 Na+/H+ antiporter subunit K05571 - - 0.000000000000000000000000000000001485 133.0
TLS3_k127_4248967_76 membrane - - - 0.00000000000000000000000000000002969 136.0
TLS3_k127_4248967_77 Pfam:DUF59 - - - 0.00000000000000000000000000000003722 130.0
TLS3_k127_4248967_78 'TIGRFAM RNA polymerase sigma factor, sigma-70 family' K03088 - - 0.00000000000000000000000000000005799 131.0
TLS3_k127_4248967_79 Protein of unknown function (DUF1579) - - - 0.0000000000000000000000000007012 121.0
TLS3_k127_4248967_8 Multicopper oxidase K22348 - 1.16.3.3 1.696e-203 644.0
TLS3_k127_4248967_80 Sigma-70 region 2 K03088 - - 0.0000000000000000000000003362 112.0
TLS3_k127_4248967_81 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000004092 111.0
TLS3_k127_4248967_82 PFAM response regulator receiver K07657 - - 0.0000000000000000000000071 106.0
TLS3_k127_4248967_83 Transcriptional regulator - - - 0.000000000000000000003819 100.0
TLS3_k127_4248967_84 GAF domain K08968 - 1.8.4.14 0.00000000000000000001117 100.0
TLS3_k127_4248967_85 COG1845 Heme copper-type cytochrome quinol oxidase subunit K02276 - 1.9.3.1 0.00000000000000000003314 98.0
TLS3_k127_4248967_86 Multiple resistance and pH regulation protein F K05570 - - 0.00000000000000005979 84.0
TLS3_k127_4248967_87 Pfam:N_methyl_2 K02456 - - 0.0000000000000001279 86.0
TLS3_k127_4248967_88 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000003851 83.0
TLS3_k127_4248967_89 Belongs to the 'phage' integrase family - - - 0.0000000000000006895 81.0
TLS3_k127_4248967_9 COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 620.0
TLS3_k127_4248967_90 Prokaryotic N-terminal methylation motif K02457 - - 0.000000000000709 78.0
TLS3_k127_4248967_91 Putative adhesin - - - 0.000000000000994 79.0
TLS3_k127_4248967_92 Tetratricopeptide repeat - - - 0.000000000001556 83.0
TLS3_k127_4248967_94 Protein of unknown function (DUF2695) - - - 0.00000000001292 71.0
TLS3_k127_4248967_95 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000004444 74.0
TLS3_k127_4248967_97 STAS domain K04749 - - 0.00000000328 64.0
TLS3_k127_4248967_98 Phage integrase family K04763 - - 0.0000003471 57.0
TLS3_k127_4248967_99 EF-hand domain pair - - - 0.000003873 57.0
TLS3_k127_4671259_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 2.941e-314 990.0
TLS3_k127_4671259_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 4.499e-306 962.0
TLS3_k127_4671259_10 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 560.0
TLS3_k127_4671259_100 secretion pathway protein K02453 - - 0.00000001212 68.0
TLS3_k127_4671259_101 paraquat-inducible protein A K03808 - - 0.00000003897 62.0
TLS3_k127_4671259_102 Phospholipid methyltransferase - - - 0.00000009356 60.0
TLS3_k127_4671259_103 CAAX protease K07052 - - 0.0000001953 63.0
TLS3_k127_4671259_104 PFAM O-Antigen - - - 0.0000003304 64.0
TLS3_k127_4671259_105 Protein of unknown function (DUF1559) K02456 - - 0.0000006041 61.0
TLS3_k127_4671259_106 general secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.000001877 58.0
TLS3_k127_4671259_108 Flagellar basal body P-ring biosynthesis protein K02386 - - 0.000005983 58.0
TLS3_k127_4671259_109 Belongs to the peptidase S16 family K07177 - - 0.000007533 58.0
TLS3_k127_4671259_11 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 522.0
TLS3_k127_4671259_110 - - - - 0.00001442 49.0
TLS3_k127_4671259_111 interspecies interaction between organisms K18353 - - 0.00005266 55.0
TLS3_k127_4671259_112 Protein of unknown function (DUF1559) - - - 0.0001661 52.0
TLS3_k127_4671259_113 Type II secretion system (T2SS), protein K - - - 0.0003164 53.0
TLS3_k127_4671259_114 - - - - 0.0003927 49.0
TLS3_k127_4671259_115 Belongs to the GSP D family K02453 - - 0.0008042 51.0
TLS3_k127_4671259_12 folylpolyglutamate synthase K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 515.0
TLS3_k127_4671259_13 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00819,K00821 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 486.0
TLS3_k127_4671259_14 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 469.0
TLS3_k127_4671259_15 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 447.0
TLS3_k127_4671259_16 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 436.0
TLS3_k127_4671259_17 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 419.0
TLS3_k127_4671259_18 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 433.0
TLS3_k127_4671259_19 PFAM ABC transporter related K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 423.0
TLS3_k127_4671259_2 Domain of unknown function (DUF5117) - - - 1.485e-290 921.0
TLS3_k127_4671259_20 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 385.0
TLS3_k127_4671259_21 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 368.0
TLS3_k127_4671259_22 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 340.0
TLS3_k127_4671259_23 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 328.0
TLS3_k127_4671259_24 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 320.0
TLS3_k127_4671259_25 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 318.0
TLS3_k127_4671259_26 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 318.0
TLS3_k127_4671259_27 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 310.0
TLS3_k127_4671259_28 Hydroxymethylglutaryl-CoA lyase K01640 GO:0003674,GO:0003824,GO:0004419,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 296.0
TLS3_k127_4671259_29 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001158 291.0
TLS3_k127_4671259_3 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 9.597e-287 913.0
TLS3_k127_4671259_30 PFAM FIST C domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001517 293.0
TLS3_k127_4671259_31 Na+/Pi-cotransporter K03324 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004501 297.0
TLS3_k127_4671259_32 Binding-protein-dependent transport system inner membrane component K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005185 287.0
TLS3_k127_4671259_33 Flagellar basal body rod protein K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000126 282.0
TLS3_k127_4671259_34 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001342 282.0
TLS3_k127_4671259_35 homoserine kinase activity K02204,K13059 - 2.7.1.162,2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001573 288.0
TLS3_k127_4671259_36 Type 4 fimbrial assembly protein pilC K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007346 284.0
TLS3_k127_4671259_37 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004689 276.0
TLS3_k127_4671259_38 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004747 274.0
TLS3_k127_4671259_39 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003309 274.0
TLS3_k127_4671259_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.109e-263 842.0
TLS3_k127_4671259_40 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000001964 268.0
TLS3_k127_4671259_41 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000678 263.0
TLS3_k127_4671259_42 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000005187 260.0
TLS3_k127_4671259_43 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001963 262.0
TLS3_k127_4671259_44 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000006146 268.0
TLS3_k127_4671259_45 general secretion pathway protein D K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001993 281.0
TLS3_k127_4671259_46 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003715 260.0
TLS3_k127_4671259_47 tyrosine recombinase XerC K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002162 252.0
TLS3_k127_4671259_48 PLD-like domain K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005875 256.0
TLS3_k127_4671259_49 stress-induced protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000011 243.0
TLS3_k127_4671259_5 Ribosomal protein S1 K02945 - - 3.691e-255 801.0
TLS3_k127_4671259_50 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000009625 217.0
TLS3_k127_4671259_51 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000273 214.0
TLS3_k127_4671259_52 cobalamin binding - - - 0.0000000000000000000000000000000000000000000000000000000003414 214.0
TLS3_k127_4671259_53 Domain of unknown function (DUF892) - - - 0.000000000000000000000000000000000000000000000000000000005053 203.0
TLS3_k127_4671259_54 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000001194 202.0
TLS3_k127_4671259_55 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000001632 220.0
TLS3_k127_4671259_56 Domain of unknown function (DUF4375) - - - 0.00000000000000000000000000000000000000000000000000002244 205.0
TLS3_k127_4671259_57 The glycine cleavage system catalyzes the degradation of glycine K00605,K06980,K22086 - 1.5.99.5,2.1.2.10 0.00000000000000000000000000000000000000000000000000004952 203.0
TLS3_k127_4671259_58 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000000000000009809 194.0
TLS3_k127_4671259_59 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000408 189.0
TLS3_k127_4671259_6 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.723e-225 718.0
TLS3_k127_4671259_60 Cellulose binding domain K07004 - - 0.0000000000000000000000000000000000000000000000000006331 194.0
TLS3_k127_4671259_61 Nacht domain - - - 0.00000000000000000000000000000000000000000000000004022 191.0
TLS3_k127_4671259_62 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000006771 183.0
TLS3_k127_4671259_63 spectrin binding K15502,K15503 - - 0.00000000000000000000000000000000000000000000002511 182.0
TLS3_k127_4671259_64 basal body rod protein K02391,K02392 - - 0.000000000000000000000000000000000000000000001058 177.0
TLS3_k127_4671259_65 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000002505 163.0
TLS3_k127_4671259_66 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000000000000000001243 169.0
TLS3_k127_4671259_67 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000000000000000221 162.0
TLS3_k127_4671259_68 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000001086 157.0
TLS3_k127_4671259_69 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000007406 155.0
TLS3_k127_4671259_7 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 5.32e-222 700.0
TLS3_k127_4671259_70 Scavenger mRNA decapping enzyme C-term binding K19710 - 2.7.7.53 0.0000000000000000000000000000000000003482 146.0
TLS3_k127_4671259_71 sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family K15913 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.3.1.203 0.000000000000000000000000000000000004643 148.0
TLS3_k127_4671259_72 response regulator receiver - - - 0.0000000000000000000000000000000005856 136.0
TLS3_k127_4671259_73 Peptidase C26 K01658,K07010 - 4.1.3.27 0.0000000000000000000000000000000009834 140.0
TLS3_k127_4671259_74 ECF sigma factor K03088 - - 0.000000000000000000000000000000004481 139.0
TLS3_k127_4671259_75 DNA recombination K03497,K13582 - - 0.00000000000000000000000000000001981 142.0
TLS3_k127_4671259_76 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000002917 133.0
TLS3_k127_4671259_77 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000007881 126.0
TLS3_k127_4671259_79 Thioesterase - - - 0.0000000000000000000000000003425 119.0
TLS3_k127_4671259_8 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.44e-221 697.0
TLS3_k127_4671259_80 - - - - 0.00000000000000000000000008807 115.0
TLS3_k127_4671259_81 Peptide-N-glycosidase F, N terminal - - - 0.0000000000000000000000003199 118.0
TLS3_k127_4671259_82 ACT domain - - - 0.0000000000000000000000006509 108.0
TLS3_k127_4671259_83 Ankyrin repeat - - - 0.0000000000000000000002322 111.0
TLS3_k127_4671259_84 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.000000000000000000001163 104.0
TLS3_k127_4671259_85 - - - - 0.000000000000000000003433 98.0
TLS3_k127_4671259_86 - - - - 0.000000000000000000004277 101.0
TLS3_k127_4671259_87 Tetratricopeptide repeat - - - 0.00000000000000000004277 104.0
TLS3_k127_4671259_88 general secretion pathway protein G K02456 - - 0.0000000000000000002364 94.0
TLS3_k127_4671259_89 Protein of unknown function (DUF1569) - - - 0.000000000000000000508 94.0
TLS3_k127_4671259_9 COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 568.0
TLS3_k127_4671259_91 Protein of unknown function (DUF4026) - - - 0.0000000000000005533 91.0
TLS3_k127_4671259_92 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000007939 81.0
TLS3_k127_4671259_93 PFAM Fimbrial assembly family protein - - - 0.00000000000003205 86.0
TLS3_k127_4671259_94 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000005562 78.0
TLS3_k127_4671259_95 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000741 78.0
TLS3_k127_4671259_96 Alpha beta hydrolase - - - 0.0000000000001074 82.0
TLS3_k127_4671259_97 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000003094 75.0
TLS3_k127_4671259_98 protein conserved in bacteria - - - 0.00000000000626 79.0
TLS3_k127_4671259_99 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000686 66.0
TLS3_k127_4790564_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 586.0
TLS3_k127_4790564_1 PFAM Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007635 383.0
TLS3_k127_4790564_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 376.0
TLS3_k127_4790564_3 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 362.0
TLS3_k127_4790564_4 - - - - 0.0000000000000000000000000000000000000000009096 169.0
TLS3_k127_4790564_5 CYTH - - - 0.000000000000000000000000001769 118.0
TLS3_k127_4790564_6 Sigma-70 region 2 - - - 0.0000000000000000000001754 107.0
TLS3_k127_4790564_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000008951 78.0
TLS3_k127_4790564_8 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000942 66.0
TLS3_k127_4910039_0 DNA segregation ATPase FtsK SpoIIIE K03466 - - 0.0 1128.0
TLS3_k127_4910039_1 Nacht domain - - - 2.481e-268 885.0
TLS3_k127_4910039_10 Pentapeptide repeats (9 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 578.0
TLS3_k127_4910039_100 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00000000000000000000000000000000002948 154.0
TLS3_k127_4910039_101 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.0000000000000000000000000000000008315 132.0
TLS3_k127_4910039_102 Proteins of 100 residues with WXG - - - 0.000000000000000000000000000000002881 130.0
TLS3_k127_4910039_103 Recombinase - - - 0.00000000000000000000000000000001358 146.0
TLS3_k127_4910039_104 Putative PD-(D/E)XK family member, (DUF4420) - - - 0.00000000000000000000000000000002643 140.0
TLS3_k127_4910039_105 - - - - 0.0000000000000000000000000000003122 132.0
TLS3_k127_4910039_106 - - - - 0.0000000000000000000000000000008097 141.0
TLS3_k127_4910039_107 Protein involved in cellulose biosynthesis - - - 0.0000000000000000000000000001461 129.0
TLS3_k127_4910039_108 cell redox homeostasis - - - 0.0000000000000000000000000004166 121.0
TLS3_k127_4910039_109 endonuclease activity K07451 - - 0.000000000000000000000000001806 114.0
TLS3_k127_4910039_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 529.0
TLS3_k127_4910039_110 TIGRFAM Phage - - - 0.000000000000000000000000006797 115.0
TLS3_k127_4910039_111 Protein of unknown function (DUF1579) - - - 0.00000000000000000000001139 112.0
TLS3_k127_4910039_112 ATP-dependent peptidase activity K07452 - - 0.00000000000000000000001309 111.0
TLS3_k127_4910039_113 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000293 103.0
TLS3_k127_4910039_114 DNA binding - - - 0.0000000000000000000008419 108.0
TLS3_k127_4910039_115 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000001276 97.0
TLS3_k127_4910039_116 - - - - 0.000000000000000000002628 105.0
TLS3_k127_4910039_117 UPF0761 membrane protein K07058 - - 0.000000000000000000005889 107.0
TLS3_k127_4910039_118 - - - - 0.00000000000000000004278 98.0
TLS3_k127_4910039_119 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000004994 92.0
TLS3_k127_4910039_12 Zinc-binding dehydrogenase K13979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 522.0
TLS3_k127_4910039_120 DNA integration K07497 - - 0.00000000000000000008496 91.0
TLS3_k127_4910039_122 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000001034 86.0
TLS3_k127_4910039_125 Protein of unknown function (DUF1444) - - - 0.00000000000000003137 92.0
TLS3_k127_4910039_126 Sigma factor PP2C-like phosphatases - - - 0.00000000000000006725 89.0
TLS3_k127_4910039_127 - - - - 0.00000000000000007315 90.0
TLS3_k127_4910039_128 - - - - 0.0000000000000001093 83.0
TLS3_k127_4910039_129 Peptidase C13 family - - - 0.0000000000000001678 93.0
TLS3_k127_4910039_13 Tetratricopeptide repeat K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 517.0
TLS3_k127_4910039_131 oxidoreductase activity K07114 - - 0.000000000000001225 89.0
TLS3_k127_4910039_132 antisigma factor binding K04749 - - 0.000000000000002108 79.0
TLS3_k127_4910039_133 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000004049 78.0
TLS3_k127_4910039_134 nucleotidyltransferase activity - - - 0.000000000000004298 83.0
TLS3_k127_4910039_135 - - - - 0.000000000000008147 82.0
TLS3_k127_4910039_136 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000001108 82.0
TLS3_k127_4910039_138 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000004693 77.0
TLS3_k127_4910039_14 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family K00558 - 2.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 485.0
TLS3_k127_4910039_140 - - - - 0.00000000002302 74.0
TLS3_k127_4910039_141 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000347 71.0
TLS3_k127_4910039_143 Subtilase family K01179,K13276 GO:0005575,GO:0005576 3.2.1.4 0.000000002173 72.0
TLS3_k127_4910039_144 4Fe-4S dicluster domain K00184 - - 0.000000003612 61.0
TLS3_k127_4910039_146 Helix-turn-helix XRE-family like proteins - - - 0.0000001807 55.0
TLS3_k127_4910039_148 Histidine kinase K11633 - 2.7.13.3 0.0000002425 64.0
TLS3_k127_4910039_149 AAA domain (dynein-related subfamily) K07452 - - 0.0000002474 61.0
TLS3_k127_4910039_15 bifunctional purine biosynthesis protein purh K00602 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 486.0
TLS3_k127_4910039_150 Helix-turn-helix domain - - - 0.0000002482 55.0
TLS3_k127_4910039_151 Restriction endonuclease K07448 - - 0.0000002675 63.0
TLS3_k127_4910039_152 biopolymer transport protein K03559 - - 0.0000007628 57.0
TLS3_k127_4910039_154 Methyltransferase domain - - - 0.000001676 59.0
TLS3_k127_4910039_155 serine threonine protein kinase - - - 0.000002545 60.0
TLS3_k127_4910039_157 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000009855 57.0
TLS3_k127_4910039_158 - - - - 0.00001538 55.0
TLS3_k127_4910039_159 Glycosyl transferases group 1 - - - 0.00001596 57.0
TLS3_k127_4910039_16 MgtE intracellular N domain K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 480.0
TLS3_k127_4910039_160 - - - - 0.00002032 48.0
TLS3_k127_4910039_162 Transcription factor K19871 GO:0000003,GO:0000118,GO:0000122,GO:0000228,GO:0000381,GO:0000785,GO:0000790,GO:0000792,GO:0000976,GO:0000977,GO:0000981,GO:0001012,GO:0001067,GO:0001085,GO:0001158,GO:0001654,GO:0001655,GO:0001656,GO:0001657,GO:0001658,GO:0001667,GO:0001704,GO:0001707,GO:0001708,GO:0001709,GO:0001742,GO:0001745,GO:0001751,GO:0001754,GO:0001763,GO:0001822,GO:0001823,GO:0001838,GO:0001841,GO:0001843,GO:0002009,GO:0002165,GO:0003002,GO:0003006,GO:0003008,GO:0003205,GO:0003231,GO:0003279,GO:0003281,GO:0003337,GO:0003338,GO:0003339,GO:0003340,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003700,GO:0003712,GO:0003713,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006725,GO:0006807,GO:0006928,GO:0007154,GO:0007165,GO:0007275,GO:0007369,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007423,GO:0007424,GO:0007427,GO:0007438,GO:0007444,GO:0007469,GO:0007472,GO:0007476,GO:0007498,GO:0007507,GO:0007517,GO:0007525,GO:0007548,GO:0007552,GO:0007560,GO:0007600,GO:0007605,GO:0008013,GO:0008134,GO:0008150,GO:0008152,GO:0008406,GO:0008584,GO:0008586,GO:0008589,GO:0009058,GO:0009059,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0009996,GO:0010001,GO:0010369,GO:0010453,GO:0010454,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010631,GO:0010646,GO:0010647,GO:0010648,GO:0010720,GO:0014016,GO:0014020,GO:0016070,GO:0016331,GO:0016477,GO:0016581,GO:0017053,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019827,GO:0021536,GO:0021537,GO:0021545,GO:0021553,GO:0021675,GO:0021772,GO:0021782,GO:0021872,GO:0021879,GO:0021884,GO:0021889,GO:0021891,GO:0021915,GO:0021953,GO:0021954,GO:0021983,GO:0021988,GO:0022008,GO:0022414,GO:0022603,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030111,GO:0030154,GO:0030177,GO:0030182,GO:0030325,GO:0030326,GO:0030539,GO:0030855,GO:0030856,GO:0030857,GO:0030900,GO:0031128,GO:0031129,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032774,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0035019,GO:0035107,GO:0035108,GO:0035113,GO:0035114,GO:0035120,GO:0035136,GO:0035137,GO:0035148,GO:0035155,GO:0035214,GO:0035220,GO:0035239,GO:0035270,GO:0035277,GO:0035295,GO:0035309,GO:0035310,GO:0035326,GO:0035850,GO:0040007,GO:0040011,GO:0042063,GO:0042127,GO:0042471,GO:0042473,GO:0042659,GO:0042692,GO:0042733,GO:0043009,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043484,GO:0043565,GO:0043583,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0045137,GO:0045165,GO:0045465,GO:0045466,GO:0045595,GO:0045596,GO:0045597,GO:0045664,GO:0045666,GO:0045879,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0046530,GO:0046546,GO:0046661,GO:0046845,GO:0048024,GO:0048098,GO:0048332,GO:0048333,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048562,GO:0048563,GO:0048565,GO:0048566,GO:0048568,GO:0048569,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048592,GO:0048598,GO:0048608,GO:0048644,GO:0048646,GO:0048666,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048732,GO:0048736,GO:0048737,GO:0048749,GO:0048754,GO:0048806,GO:0048856,GO:0048863,GO:0048869,GO:0048870,GO:0050684,GO:0050767,GO:0050769,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050896,GO:0050954,GO:0051093,GO:0051094,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051239,GO:0051240,GO:0051241,GO:0051252,GO:0051253,GO:0051254,GO:0051674,GO:0051716,GO:0051960,GO:0051962,GO:0055123,GO:0060173,GO:0060231,GO:0060255,GO:0060284,GO:0060290,GO:0060322,GO:0060429,GO:0060541,GO:0060560,GO:0060562,GO:0060573,GO:0060581,GO:0060606,GO:0060675,GO:0060677,GO:0060688,GO:0060993,GO:0061005,GO:0061034,GO:0061061,GO:0061138,GO:0061213,GO:0061217,GO:0061326,GO:0061333,GO:0061458,GO:0065007,GO:0070013,GO:0070603,GO:0071704,GO:0072001,GO:0072006,GO:0072009,GO:0072028,GO:0072033,GO:0072038,GO:0072073,GO:0072077,GO:0072078,GO:0072080,GO:0072087,GO:0072088,GO:0072092,GO:0072093,GO:0072163,GO:0072164,GO:0072171,GO:0072175,GO:0072202,GO:0072210,GO:0072215,GO:0072217,GO:0072273,GO:0072283,GO:0072309,GO:0072359,GO:0080090,GO:0090130,GO:0090132,GO:0090183,GO:0090184,GO:0090185,GO:0090189,GO:0090190,GO:0090304,GO:0090545,GO:0090568,GO:0090596,GO:0097159,GO:0097659,GO:0098687,GO:0098727,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1902679,GO:1902680,GO:1903311,GO:1903506,GO:1903507,GO:1903508,GO:1904949,GO:1905330,GO:1905331,GO:1905332,GO:1990837,GO:2000026,GO:2000027,GO:2000112,GO:2000113,GO:2000177,GO:2000380,GO:2000381,GO:2000383,GO:2000384,GO:2000696,GO:2000697,GO:2001141 - 0.0001341 45.0
TLS3_k127_4910039_163 Serine threonine protein kinase K12132 - 2.7.11.1 0.0001474 55.0
TLS3_k127_4910039_164 antisigma factor binding K04749,K20978 - - 0.0003225 49.0
TLS3_k127_4910039_166 antisigma factor binding K04749 - - 0.0004734 47.0
TLS3_k127_4910039_167 biopolymer transport protein K03559 - - 0.0006452 48.0
TLS3_k127_4910039_17 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 465.0
TLS3_k127_4910039_18 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 435.0
TLS3_k127_4910039_19 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 436.0
TLS3_k127_4910039_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 3.5e-236 749.0
TLS3_k127_4910039_20 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 444.0
TLS3_k127_4910039_21 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 432.0
TLS3_k127_4910039_22 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 426.0
TLS3_k127_4910039_23 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 409.0
TLS3_k127_4910039_24 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 404.0
TLS3_k127_4910039_25 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007749 418.0
TLS3_k127_4910039_26 rna polymerase sigma-54 factor K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 398.0
TLS3_k127_4910039_27 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 390.0
TLS3_k127_4910039_28 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 372.0
TLS3_k127_4910039_29 protein.. Source PGD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 379.0
TLS3_k127_4910039_3 COG1239 Mg-chelatase subunit ChlI K03405 - 6.6.1.1 6.044e-234 732.0
TLS3_k127_4910039_30 Belongs to the N(4) N(6)-methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 374.0
TLS3_k127_4910039_31 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 356.0
TLS3_k127_4910039_32 TIGRFAM Phage - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 357.0
TLS3_k127_4910039_33 Catalyzes the specific phosphorylation of arginine residues in proteins K19405 - 2.7.14.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 341.0
TLS3_k127_4910039_34 alginic acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 351.0
TLS3_k127_4910039_35 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 328.0
TLS3_k127_4910039_36 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 317.0
TLS3_k127_4910039_37 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 333.0
TLS3_k127_4910039_38 homoserine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 321.0
TLS3_k127_4910039_39 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 305.0
TLS3_k127_4910039_4 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 2.02e-219 694.0
TLS3_k127_4910039_40 Belongs to the class-I aminoacyl-tRNA synthetase family K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 313.0
TLS3_k127_4910039_41 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 306.0
TLS3_k127_4910039_42 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 292.0
TLS3_k127_4910039_43 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 290.0
TLS3_k127_4910039_44 Belongs to the KdsA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 290.0
TLS3_k127_4910039_45 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009484 290.0
TLS3_k127_4910039_46 tRNA cytidylyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001126 289.0
TLS3_k127_4910039_47 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001111 282.0
TLS3_k127_4910039_48 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001324 285.0
TLS3_k127_4910039_49 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007172 292.0
TLS3_k127_4910039_5 serine-type peptidase activity K01303 - 3.4.19.1 2.16e-205 659.0
TLS3_k127_4910039_50 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000013 273.0
TLS3_k127_4910039_51 Integral membrane protein (PIN domain superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001361 286.0
TLS3_k127_4910039_52 BtpA family K06971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002033 274.0
TLS3_k127_4910039_53 calcium- and calmodulin-responsive adenylate cyclase activity K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000004409 281.0
TLS3_k127_4910039_54 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000002045 264.0
TLS3_k127_4910039_55 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000002769 259.0
TLS3_k127_4910039_56 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003575 270.0
TLS3_k127_4910039_57 C-terminal PDZ domain K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000005609 261.0
TLS3_k127_4910039_58 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001127 259.0
TLS3_k127_4910039_59 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000002463 247.0
TLS3_k127_4910039_6 cellulose binding - - - 1.434e-204 642.0
TLS3_k127_4910039_60 Glycosyl transferase, family 2 K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000323 256.0
TLS3_k127_4910039_61 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001006 248.0
TLS3_k127_4910039_62 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002997 244.0
TLS3_k127_4910039_63 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs - - - 0.0000000000000000000000000000000000000000000000000000000000000000005227 242.0
TLS3_k127_4910039_64 amino acid transport K01713,K02029,K02030,K09997,K10014 - 4.2.1.51,4.2.1.91 0.0000000000000000000000000000000000000000000000000000000000000000006469 238.0
TLS3_k127_4910039_65 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000001213 230.0
TLS3_k127_4910039_67 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000003686 220.0
TLS3_k127_4910039_68 succinate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000001172 222.0
TLS3_k127_4910039_69 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000001101 216.0
TLS3_k127_4910039_7 PFAM Z1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 582.0
TLS3_k127_4910039_70 - - - - 0.0000000000000000000000000000000000000000000000000000000003656 209.0
TLS3_k127_4910039_71 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000003988 213.0
TLS3_k127_4910039_72 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000004072 208.0
TLS3_k127_4910039_73 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000002075 207.0
TLS3_k127_4910039_74 Guanine deaminase K01487 - 3.5.4.3 0.00000000000000000000000000000000000000000000000000000002786 213.0
TLS3_k127_4910039_75 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000805 198.0
TLS3_k127_4910039_76 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000009013 206.0
TLS3_k127_4910039_77 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000002461 191.0
TLS3_k127_4910039_78 COG0657 Esterase lipase - - - 0.00000000000000000000000000000000000000000000000000003186 201.0
TLS3_k127_4910039_79 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000001084 186.0
TLS3_k127_4910039_8 COG0659 Sulfate permease and related transporters (MFS superfamily) K01673,K03321 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 571.0
TLS3_k127_4910039_80 acetyltransferase K18815 - 2.3.1.82 0.0000000000000000000000000000000000000000000000000981 183.0
TLS3_k127_4910039_81 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000009588 186.0
TLS3_k127_4910039_82 FR47-like protein - - - 0.00000000000000000000000000000000000000000000002336 175.0
TLS3_k127_4910039_83 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000004154 171.0
TLS3_k127_4910039_84 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0034214,GO:0042802,GO:0043170,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0061799,GO:0065003,GO:0071704,GO:0071840,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 0.0000000000000000000000000000000000000000000117 168.0
TLS3_k127_4910039_85 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000002257 166.0
TLS3_k127_4910039_86 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000005118 185.0
TLS3_k127_4910039_87 riboflavin synthase, alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.00000000000000000000000000000000000000000005317 168.0
TLS3_k127_4910039_88 response regulator receiver K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000009382 163.0
TLS3_k127_4910039_89 MotA/TolQ/ExbB proton channel family - - - 0.000000000000000000000000000000000000000003934 168.0
TLS3_k127_4910039_9 lysine 2,3-aminomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 561.0
TLS3_k127_4910039_90 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.00000000000000000000000000000000000000001404 164.0
TLS3_k127_4910039_91 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000002851 155.0
TLS3_k127_4910039_92 protein with conserved CXXC pairs K19411 - - 0.00000000000000000000000000000000000000003788 157.0
TLS3_k127_4910039_93 acid phosphatase activity - - - 0.00000000000000000000000000000000000000013 172.0
TLS3_k127_4910039_94 peptidase activity, acting on L-amino acid peptides - - - 0.000000000000000000000000000000000000005314 169.0
TLS3_k127_4910039_95 PFAM Rhomboid family - - - 0.00000000000000000000000000000000000001504 160.0
TLS3_k127_4910039_96 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000003275 151.0
TLS3_k127_4910039_97 HNH endonuclease K07454 - - 0.0000000000000000000000000000000000000799 145.0
TLS3_k127_4910039_98 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.000000000000000000000000000000000001495 145.0
TLS3_k127_4910039_99 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.000000000000000000000000000000000007543 156.0
TLS3_k127_5192983_0 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.0 1264.0
TLS3_k127_5192983_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1043.0
TLS3_k127_5192983_10 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007859 356.0
TLS3_k127_5192983_11 Pkd domain containing protein K01337 - 3.4.21.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 347.0
TLS3_k127_5192983_12 Major Facilitator K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 334.0
TLS3_k127_5192983_13 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000116 291.0
TLS3_k127_5192983_14 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001573 293.0
TLS3_k127_5192983_15 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000003226 242.0
TLS3_k127_5192983_16 methyltransferase K03183,K21600 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000008188 231.0
TLS3_k127_5192983_17 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000001194 209.0
TLS3_k127_5192983_18 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000005209 199.0
TLS3_k127_5192983_19 Protein conserved in bacteria K09922 - - 0.0000000000000000000000000000000000000000000000001932 179.0
TLS3_k127_5192983_2 Domain of unknown function (DUF5117) - - - 1.076e-275 882.0
TLS3_k127_5192983_20 response regulator - - - 0.000000000000000000000000000000000000000009483 161.0
TLS3_k127_5192983_21 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.0000000000000000000000000000000000000001985 155.0
TLS3_k127_5192983_22 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000009965 145.0
TLS3_k127_5192983_23 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 GO:0002097,GO:0002101,GO:0002136,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0032267,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 6.3.4.19 0.0000000000000000000000000000000002731 145.0
TLS3_k127_5192983_24 PFAM PRC-barrel domain - - - 0.0000000000000000000000000000000008359 147.0
TLS3_k127_5192983_25 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000002046 118.0
TLS3_k127_5192983_26 HAD-superfamily hydrolase, subfamily IIB - - - 0.0000000000000000000000006023 117.0
TLS3_k127_5192983_27 response regulator, receiver - - - 0.000000000000000000000008454 113.0
TLS3_k127_5192983_28 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000002264 102.0
TLS3_k127_5192983_29 Acyl-ACP thioesterase - - - 0.000000000000000000001866 100.0
TLS3_k127_5192983_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 522.0
TLS3_k127_5192983_30 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.000000000000000000002325 100.0
TLS3_k127_5192983_31 - - - - 0.00000000000000000005152 104.0
TLS3_k127_5192983_32 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000001386 84.0
TLS3_k127_5192983_33 Ribosomal protein L11 methyltransferase (PrmA) K02493 - 2.1.1.297 0.000000000001364 77.0
TLS3_k127_5192983_34 Response regulator receiver domain K03413 - - 0.00000000009943 68.0
TLS3_k127_5192983_35 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000001607 74.0
TLS3_k127_5192983_36 Endonuclease exonuclease phosphatase family - - - 0.0000000003344 72.0
TLS3_k127_5192983_38 domain, Protein - - - 0.00000002307 67.0
TLS3_k127_5192983_39 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.0000001238 64.0
TLS3_k127_5192983_4 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 516.0
TLS3_k127_5192983_40 Glycosyl transferases group 1 - - - 0.00001135 57.0
TLS3_k127_5192983_42 Anaphase-promoting complex subunit Apc3 K03350 GO:0000070,GO:0000151,GO:0000152,GO:0000278,GO:0000280,GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005680,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006996,GO:0007049,GO:0007050,GO:0007059,GO:0007088,GO:0007346,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009896,GO:0009987,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0016043,GO:0016567,GO:0019538,GO:0019941,GO:0022402,GO:0030071,GO:0030163,GO:0031145,GO:0031331,GO:0031461,GO:0031974,GO:0031981,GO:0032270,GO:0032436,GO:0032446,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0036211,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045732,GO:0045786,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045930,GO:0045931,GO:0048285,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051247,GO:0051276,GO:0051603,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0062033,GO:0065007,GO:0070013,GO:0070647,GO:0071704,GO:0071840,GO:0071849,GO:0071850,GO:0071851,GO:0090068,GO:0097159,GO:0098813,GO:0140014,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1903047,GO:1903052,GO:1903364,GO:1905818,GO:1905820,GO:1990234,GO:2001252 - 0.0004561 52.0
TLS3_k127_5192983_5 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 481.0
TLS3_k127_5192983_6 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 468.0
TLS3_k127_5192983_7 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 451.0
TLS3_k127_5192983_8 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 400.0
TLS3_k127_5192983_9 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 397.0
TLS3_k127_5576943_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.837e-251 784.0
TLS3_k127_5576943_1 metalloendopeptidase activity K01392,K01414 - 3.4.24.15,3.4.24.70 9.661e-238 753.0
TLS3_k127_5576943_2 Belongs to the helicase family. UvrD subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 538.0
TLS3_k127_5576943_3 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 486.0
TLS3_k127_5576943_4 Domain of unknown function (DUF4870) K09940 - - 0.0000000000000000000000000000000001716 136.0
TLS3_k127_5576943_5 peptidyl-prolyl cis-trans isomerase K03772 - 5.2.1.8 0.0000000000000000000000000000000001725 143.0
TLS3_k127_5576943_6 Putative transmembrane protein (PGPGW) - - - 0.0000000000000000000000000000000002315 137.0
TLS3_k127_5576943_7 - - - - 0.0000000000000000000000001657 116.0
TLS3_k127_5576943_8 Domain of unknown function (DUF4870) K09940 - - 0.0000000000001072 78.0
TLS3_k127_5659448_0 Subunit R is required for both nuclease and ATPase activities, but not for modification - - - 0.0 1555.0
TLS3_k127_5659448_1 HsdM N-terminal domain K03427 - 2.1.1.72 6.832e-298 923.0
TLS3_k127_5659448_2 Predicted membrane protein (DUF2254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 509.0
TLS3_k127_5659448_3 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 379.0
TLS3_k127_5659448_4 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002683 254.0
TLS3_k127_5659448_5 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000001001 156.0
TLS3_k127_5659448_6 ATPase activity - - - 0.00000000000000000000001359 118.0
TLS3_k127_5659448_7 Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome - - - 0.0000002656 58.0
TLS3_k127_5659448_8 - - - - 0.0002017 51.0
TLS3_k127_5942170_0 Peptidase dimerisation domain K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 612.0
TLS3_k127_5942170_1 tRNA-splicing ligase RtcB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 579.0
TLS3_k127_5942170_10 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000003727 203.0
TLS3_k127_5942170_11 extracellular polysaccharide biosynthetic process K16554,K16692 - - 0.0000000000000000000000000000000001202 153.0
TLS3_k127_5942170_13 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.000000000000000000000000634 123.0
TLS3_k127_5942170_14 Lipid A 3-O-deacylase (PagL) - - - 0.000000000000000000000005064 111.0
TLS3_k127_5942170_15 PEP-CTERM system TPR-repeat lipoprotein - - - 0.00000000000000000000001076 119.0
TLS3_k127_5942170_16 Spore Coat K01790 - 5.1.3.13 0.00000000000000000000001822 107.0
TLS3_k127_5942170_18 Histidine kinase - - - 0.0000000000000000000002582 111.0
TLS3_k127_5942170_19 Histidine kinase - - - 0.0000000000000000000006309 110.0
TLS3_k127_5942170_2 Fatty acid desaturase K00508 - 1.14.19.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008425 432.0
TLS3_k127_5942170_21 - - - - 0.000000000000000004928 85.0
TLS3_k127_5942170_23 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000005733 87.0
TLS3_k127_5942170_24 - - - - 0.000000001615 66.0
TLS3_k127_5942170_25 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000002049 64.0
TLS3_k127_5942170_26 von Willebrand factor, type A - - - 0.000000008188 69.0
TLS3_k127_5942170_27 - - - - 0.0000001681 61.0
TLS3_k127_5942170_28 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000005311 61.0
TLS3_k127_5942170_29 - - - - 0.000002395 57.0
TLS3_k127_5942170_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 410.0
TLS3_k127_5942170_31 helix_turn_helix, Lux Regulon - - - 0.00001781 51.0
TLS3_k127_5942170_32 Tetratricopeptide repeat - - - 0.0009447 53.0
TLS3_k127_5942170_4 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 345.0
TLS3_k127_5942170_5 ABC-type multidrug transport system ATPase K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 345.0
TLS3_k127_5942170_6 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 331.0
TLS3_k127_5942170_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 312.0
TLS3_k127_5942170_8 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000001717 232.0
TLS3_k127_5942170_9 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000006873 209.0
TLS3_k127_6207015_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1172.0
TLS3_k127_6207015_1 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 7.159e-204 680.0
TLS3_k127_6207015_10 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001019 283.0
TLS3_k127_6207015_11 signal peptide processing K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000006435 254.0
TLS3_k127_6207015_12 FG-GAP repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000344 277.0
TLS3_k127_6207015_13 - - - - 0.000000000000000000000000000000000000000000000000000000000001394 241.0
TLS3_k127_6207015_14 Metallo-peptidase family M12B Reprolysin-like - - - 0.000000000000000000000000000000000000000000000000000001937 220.0
TLS3_k127_6207015_15 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243 - 3.2.2.9 0.000000000000000000000000000000000000000000000000000002362 199.0
TLS3_k127_6207015_16 SMART Integrin alpha beta-propellor repeat protein - - - 0.00000000000000000000000000000000000000000002084 181.0
TLS3_k127_6207015_17 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000002154 148.0
TLS3_k127_6207015_18 Antirepressor regulating drug resistance - - - 0.0000000000000000000000000000000002201 153.0
TLS3_k127_6207015_19 Belongs to the ompA family - - - 0.0000000000000000000000000000007212 143.0
TLS3_k127_6207015_2 COG2059 Chromate transport protein ChrA K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 547.0
TLS3_k127_6207015_20 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000004333 136.0
TLS3_k127_6207015_21 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000002062 104.0
TLS3_k127_6207015_22 Hep Hag repeat protein - - - 0.00000000000000000000006107 109.0
TLS3_k127_6207015_23 Biopolymer transport protein K03559 - - 0.000000000000000000003823 98.0
TLS3_k127_6207015_24 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000002178 99.0
TLS3_k127_6207015_25 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000007145 98.0
TLS3_k127_6207015_26 Belongs to the peptidase S8 family - - - 0.000000000000000001866 101.0
TLS3_k127_6207015_27 Fibronectin type III domain - - - 0.00000000000000007479 96.0
TLS3_k127_6207015_28 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K14160 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000002352 85.0
TLS3_k127_6207015_29 Tetratricopeptide repeat - - - 0.00000000000009901 86.0
TLS3_k127_6207015_3 PFAM Aldehyde dehydrogenase family K00128,K00140 - 1.2.1.18,1.2.1.27,1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 514.0
TLS3_k127_6207015_30 TIGRFAM outer membrane autotransporter barrel domain - - - 0.00000000001105 79.0
TLS3_k127_6207015_31 FHA domain K01768 - 4.6.1.1 0.000007814 57.0
TLS3_k127_6207015_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 464.0
TLS3_k127_6207015_5 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 426.0
TLS3_k127_6207015_6 Protein conserved in bacteria K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 426.0
TLS3_k127_6207015_7 Belongs to the 3-oxoacid CoA-transferase family K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 378.0
TLS3_k127_6207015_8 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001475 301.0
TLS3_k127_6207015_9 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000079 286.0
TLS3_k127_6302433_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 289.0
TLS3_k127_6302433_1 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000001146 194.0
TLS3_k127_6302433_2 indole-3-glycerol-phosphate synthase activity K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.00000000000000000000000002487 111.0
TLS3_k127_6330422_0 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 0.0 1303.0
TLS3_k127_6330422_1 Molybdopterin oxidoreductase Fe4S4 domain K02567 - - 0.0 1151.0
TLS3_k127_6330422_10 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009629 475.0
TLS3_k127_6330422_100 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000004189 118.0
TLS3_k127_6330422_101 zinc ion binding K06204 - - 0.000000000000000000000007222 113.0
TLS3_k127_6330422_103 Diacylglycerol kinase - - - 0.0000000000000000000001708 107.0
TLS3_k127_6330422_104 23S rRNA-intervening sequence protein - - - 0.0000000000000000000003485 100.0
TLS3_k127_6330422_105 - - - - 0.0000000000000000000006799 110.0
TLS3_k127_6330422_106 PKD domain - - - 0.000000000000000000002155 110.0
TLS3_k127_6330422_107 Response regulator, receiver K03413 - - 0.000000000000000000006406 99.0
TLS3_k127_6330422_108 alginic acid biosynthetic process K07004,K15125,K20276 - - 0.00000000000000000001801 101.0
TLS3_k127_6330422_109 Glycosyl transferase family 2 - - - 0.00000000000000000002744 103.0
TLS3_k127_6330422_11 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 424.0
TLS3_k127_6330422_110 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000003043 85.0
TLS3_k127_6330422_111 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000006068 82.0
TLS3_k127_6330422_112 Bacterial export proteins, family 3 K02420 - - 0.0000000000000007711 79.0
TLS3_k127_6330422_113 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000003183 79.0
TLS3_k127_6330422_114 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000003526 79.0
TLS3_k127_6330422_116 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000002644 76.0
TLS3_k127_6330422_117 - - - - 0.000000001533 68.0
TLS3_k127_6330422_118 - - - - 0.000000004266 64.0
TLS3_k127_6330422_119 Domain of unknown function (DUF4349) - - - 0.000000007797 68.0
TLS3_k127_6330422_12 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 421.0
TLS3_k127_6330422_122 Belongs to the N-Me-Phe pilin family K02650 - - 0.0000001081 59.0
TLS3_k127_6330422_123 Domain of unknown function (DUF4279) - - - 0.000003951 54.0
TLS3_k127_6330422_124 Tfp pilus assembly protein FimT K10926 - - 0.000004329 57.0
TLS3_k127_6330422_126 - - - - 0.0001727 45.0
TLS3_k127_6330422_127 flagellar K02418,K02419 - - 0.0003408 51.0
TLS3_k127_6330422_128 general secretion pathway protein G K02456 - - 0.0004736 48.0
TLS3_k127_6330422_13 Type II IV secretion system protein K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 416.0
TLS3_k127_6330422_130 mRNA catabolic process - - - 0.0009356 49.0
TLS3_k127_6330422_14 Domain of unknown function (DUF3482) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007992 407.0
TLS3_k127_6330422_15 PFAM Na Pi-cotransporter K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 413.0
TLS3_k127_6330422_16 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 395.0
TLS3_k127_6330422_17 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 390.0
TLS3_k127_6330422_18 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 400.0
TLS3_k127_6330422_19 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 369.0
TLS3_k127_6330422_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 7.224e-309 982.0
TLS3_k127_6330422_20 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 361.0
TLS3_k127_6330422_21 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 351.0
TLS3_k127_6330422_22 COG2084 3-hydroxyisobutyrate dehydrogenase and related K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 350.0
TLS3_k127_6330422_23 COG0226 ABC-type phosphate transport system periplasmic K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 351.0
TLS3_k127_6330422_24 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 347.0
TLS3_k127_6330422_25 Glucose / Sorbosone dehydrogenase K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 353.0
TLS3_k127_6330422_26 Cytidylyltransferase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 347.0
TLS3_k127_6330422_27 oxidoreductase activity K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 331.0
TLS3_k127_6330422_28 Protein of unknown function DUF115 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 355.0
TLS3_k127_6330422_29 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 317.0
TLS3_k127_6330422_3 serine-type peptidase activity - - - 2.603e-262 834.0
TLS3_k127_6330422_30 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 319.0
TLS3_k127_6330422_31 FG-GAP repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 321.0
TLS3_k127_6330422_32 pseudouridine synthase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 314.0
TLS3_k127_6330422_33 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 309.0
TLS3_k127_6330422_34 phosphate ABC transporter K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 308.0
TLS3_k127_6330422_35 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 297.0
TLS3_k127_6330422_36 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 304.0
TLS3_k127_6330422_37 uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 291.0
TLS3_k127_6330422_38 Belongs to the PdxA family K22024 - 1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009804 296.0
TLS3_k127_6330422_39 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 292.0
TLS3_k127_6330422_4 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 3.978e-228 728.0
TLS3_k127_6330422_40 PFAM MltA domain protein K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001825 299.0
TLS3_k127_6330422_41 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002545 287.0
TLS3_k127_6330422_42 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001012 285.0
TLS3_k127_6330422_43 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001027 279.0
TLS3_k127_6330422_45 COG0349 Ribonuclease D K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000004822 257.0
TLS3_k127_6330422_46 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005883 248.0
TLS3_k127_6330422_47 FlhB HrpN YscU SpaS Family K02401 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009693 249.0
TLS3_k127_6330422_48 Transcriptional regulatory protein, C terminal K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000001018 241.0
TLS3_k127_6330422_49 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002735 239.0
TLS3_k127_6330422_5 ABC-type multidrug transport system ATPase and permease K06147,K11085 - - 2.895e-226 719.0
TLS3_k127_6330422_50 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000006671 233.0
TLS3_k127_6330422_51 GTP-binding signal recognition particle SRP54 K02404 - - 0.000000000000000000000000000000000000000000000000000000000000000005283 244.0
TLS3_k127_6330422_52 NeuB family - - - 0.000000000000000000000000000000000000000000000000000000000000000007959 237.0
TLS3_k127_6330422_53 SMART Heat shock protein DnaJ K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000002646 235.0
TLS3_k127_6330422_54 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000002792 220.0
TLS3_k127_6330422_55 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000003709 226.0
TLS3_k127_6330422_56 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000002786 220.0
TLS3_k127_6330422_57 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000005785 229.0
TLS3_k127_6330422_58 PFAM type II secretion system K02653,K12278 - - 0.000000000000000000000000000000000000000000000000000000000001976 224.0
TLS3_k127_6330422_59 Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000009906 224.0
TLS3_k127_6330422_6 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 1.644e-205 671.0
TLS3_k127_6330422_60 Cytidylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000978 206.0
TLS3_k127_6330422_61 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.00000000000000000000000000000000000000000000000000000001503 206.0
TLS3_k127_6330422_62 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000007495 203.0
TLS3_k127_6330422_63 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000007074 197.0
TLS3_k127_6330422_64 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000009096 196.0
TLS3_k127_6330422_65 anaerobic respiration K02568 - - 0.0000000000000000000000000000000000000000000000000006345 193.0
TLS3_k127_6330422_66 Belongs to the ParA family K04562 - - 0.000000000000000000000000000000000000000000000000007133 195.0
TLS3_k127_6330422_67 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000002061 188.0
TLS3_k127_6330422_68 membrane - - - 0.0000000000000000000000000000000000000000000000001217 201.0
TLS3_k127_6330422_69 Flagellar biosynthesis pathway component FliR K02421 - - 0.0000000000000000000000000000000000000000000000007737 184.0
TLS3_k127_6330422_7 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and K03182 - 4.1.1.98 4.777e-204 655.0
TLS3_k127_6330422_70 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000001217 178.0
TLS3_k127_6330422_71 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000003289 179.0
TLS3_k127_6330422_72 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000005185 172.0
TLS3_k127_6330422_73 Carboxylesterase family - - - 0.00000000000000000000000000000000000000000000006412 182.0
TLS3_k127_6330422_74 bleomycin resistance protein K06996 - - 0.0000000000000000000000000000000000000000000005365 168.0
TLS3_k127_6330422_75 - - - - 0.00000000000000000000000000000000000000000002037 183.0
TLS3_k127_6330422_76 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.00000000000000000000000000000000000000000002377 176.0
TLS3_k127_6330422_77 PhoU domain K02039 - - 0.00000000000000000000000000000000000000000004523 169.0
TLS3_k127_6330422_78 Protein of unknown function, DUF480 K09915 - - 0.0000000000000000000000000000000000000000001771 167.0
TLS3_k127_6330422_79 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000000000000005609 159.0
TLS3_k127_6330422_8 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 596.0
TLS3_k127_6330422_80 radical SAM domain protein K03424 - - 0.0000000000000000000000000000000000000001677 174.0
TLS3_k127_6330422_82 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000001851 150.0
TLS3_k127_6330422_83 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000004174 154.0
TLS3_k127_6330422_84 Peptidase S16, lon domain protein K01338,K07157 - 3.4.21.53 0.0000000000000000000000000000000000001322 151.0
TLS3_k127_6330422_85 N-Acetylmuramoyl-L-alanine amidase K01448,K07273 - 3.5.1.28 0.0000000000000000000000000000000000001513 151.0
TLS3_k127_6330422_86 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000001209 146.0
TLS3_k127_6330422_87 Single-stranded DNA-binding protein K03111 - - 0.000000000000000000000000000000000005839 142.0
TLS3_k127_6330422_88 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000000001391 153.0
TLS3_k127_6330422_89 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000001266 147.0
TLS3_k127_6330422_9 Belongs to the D-alanine--D-alanine ligase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 498.0
TLS3_k127_6330422_90 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000008439 138.0
TLS3_k127_6330422_91 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000004862 133.0
TLS3_k127_6330422_92 phosphatase activity K07025,K20866 - 3.1.3.10 0.0000000000000000000000000000004334 130.0
TLS3_k127_6330422_93 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000009902 132.0
TLS3_k127_6330422_94 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000003575 139.0
TLS3_k127_6330422_95 Flagellar motor switch type III secretory pathway K02417 - - 0.0000000000000000000000000001685 120.0
TLS3_k127_6330422_96 - - - - 0.000000000000000000000000002305 122.0
TLS3_k127_6330422_97 Sulfotransferase domain - - - 0.000000000000000000000000007898 122.0
TLS3_k127_6330422_98 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000004641 126.0
TLS3_k127_6330422_99 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000001831 114.0
TLS3_k127_6442620_0 serine-type peptidase activity K01278,K01303 - 3.4.14.5,3.4.19.1 2.205e-205 673.0
TLS3_k127_6442620_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 9.043e-201 651.0
TLS3_k127_6442620_10 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 461.0
TLS3_k127_6442620_11 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 405.0
TLS3_k127_6442620_12 SigmaW regulon antibacterial - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 387.0
TLS3_k127_6442620_13 C-terminal domain of 1-Cys peroxiredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 368.0
TLS3_k127_6442620_14 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 377.0
TLS3_k127_6442620_15 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 367.0
TLS3_k127_6442620_16 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 331.0
TLS3_k127_6442620_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 323.0
TLS3_k127_6442620_18 Asparaginase K01444 - 3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 320.0
TLS3_k127_6442620_19 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005427 308.0
TLS3_k127_6442620_2 Belongs to the class-I aminoacyl-tRNA synthetase family - - - 2.067e-194 621.0
TLS3_k127_6442620_20 ParB-like nuclease domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 304.0
TLS3_k127_6442620_21 PFAM SMP-30 Gluconolaconase K08685 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 312.0
TLS3_k127_6442620_22 FG-GAP repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 314.0
TLS3_k127_6442620_23 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 296.0
TLS3_k127_6442620_24 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03086,K03093 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006571 282.0
TLS3_k127_6442620_25 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002441 273.0
TLS3_k127_6442620_26 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003688 279.0
TLS3_k127_6442620_27 PFAM Integral membrane protein TerC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009967 265.0
TLS3_k127_6442620_28 cellulose binding K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000004033 282.0
TLS3_k127_6442620_29 FG-GAP repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000107 279.0
TLS3_k127_6442620_3 DNA topoisomerase II activity K03167 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 537.0
TLS3_k127_6442620_30 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000006408 265.0
TLS3_k127_6442620_31 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001287 258.0
TLS3_k127_6442620_32 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000007614 250.0
TLS3_k127_6442620_33 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000001392 243.0
TLS3_k127_6442620_34 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000007354 243.0
TLS3_k127_6442620_35 PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000122 218.0
TLS3_k127_6442620_36 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000001635 207.0
TLS3_k127_6442620_37 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000876 196.0
TLS3_k127_6442620_38 Domain of unknown function (DUF5011) - - - 0.0000000000000000000000000000000000000000000000000371 205.0
TLS3_k127_6442620_39 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000001856 177.0
TLS3_k127_6442620_4 Utp--glucose-1-phosphate uridylyltransferase K00972,K11442 - 2.7.7.23,2.7.7.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 515.0
TLS3_k127_6442620_40 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000006196 169.0
TLS3_k127_6442620_41 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.000000000000000000000000000000000000000000001659 169.0
TLS3_k127_6442620_42 Metallo-peptidase family M12B Reprolysin-like - - - 0.0000000000000000000000000000000000000000001347 184.0
TLS3_k127_6442620_43 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000004543 168.0
TLS3_k127_6442620_44 Polynucleotide kinase 3 phosphatase - - - 0.000000000000000000000000000000000000000008701 166.0
TLS3_k127_6442620_45 regulation of RNA biosynthetic process - - - 0.0000000000000000000000000000000000000005427 155.0
TLS3_k127_6442620_46 Protein of unknown function, DUF481 - - - 0.000000000000000000000000000000000000003184 158.0
TLS3_k127_6442620_47 COG0698 Ribose 5-phosphate isomerase RpiB K01808 - 5.3.1.6 0.000000000000000000000000000000000000007059 150.0
TLS3_k127_6442620_48 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02768 - 2.7.1.202 0.000000000000000000000000000000000000007168 149.0
TLS3_k127_6442620_49 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) K02372 - 4.2.1.59 0.00000000000000000000000000000000000004177 149.0
TLS3_k127_6442620_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 496.0
TLS3_k127_6442620_50 peroxiredoxin activity - - - 0.00000000000000000000000000000000000008698 150.0
TLS3_k127_6442620_51 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000001706 155.0
TLS3_k127_6442620_52 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000004171 143.0
TLS3_k127_6442620_53 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000005926 129.0
TLS3_k127_6442620_54 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000027 126.0
TLS3_k127_6442620_56 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000001079 125.0
TLS3_k127_6442620_57 Hydrolases of the alpha beta superfamily K06889 - - 0.000000000000000000000000000131 129.0
TLS3_k127_6442620_58 Pkd domain containing protein - - - 0.000000000000000000000000001939 130.0
TLS3_k127_6442620_59 Phospholipid N-methyltransferase - - - 0.000000000000000000000000003123 121.0
TLS3_k127_6442620_6 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009057 488.0
TLS3_k127_6442620_60 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000005187 121.0
TLS3_k127_6442620_61 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000143 111.0
TLS3_k127_6442620_62 - - - - 0.00000000000000000000000002198 124.0
TLS3_k127_6442620_63 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K01808,K07566,K20201 - 2.7.7.87,3.1.3.48,3.9.1.2,5.3.1.6 0.000000000000000000006787 98.0
TLS3_k127_6442620_64 Response regulator, receiver - - - 0.0000000000000000001378 93.0
TLS3_k127_6442620_66 Conserved repeat domain - - - 0.000000000000007987 89.0
TLS3_k127_6442620_67 4 iron, 4 sulfur cluster binding - - - 0.00000000000003587 87.0
TLS3_k127_6442620_68 protein import - - - 0.000000000001724 76.0
TLS3_k127_6442620_7 Phage plasmid primase P4 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 502.0
TLS3_k127_6442620_70 Belongs to the peptidase S8 family K13735,K20276,K21449 - - 0.00000000001321 78.0
TLS3_k127_6442620_71 membrane-associated protein - - - 0.00000000002047 74.0
TLS3_k127_6442620_73 nuclease K01174 - 3.1.31.1 0.00000000007669 70.0
TLS3_k127_6442620_74 DNA primase - - - 0.0000000001585 75.0
TLS3_k127_6442620_75 CARDB - - - 0.0000000005872 72.0
TLS3_k127_6442620_76 Glycine zipper - - - 0.000000001371 63.0
TLS3_k127_6442620_77 Domain of unknown function (DUF4982) - - - 0.000000008889 69.0
TLS3_k127_6442620_78 - - - - 0.00000002276 65.0
TLS3_k127_6442620_79 Non-ribosomal peptide synthetase modules and related proteins - - - 0.0000006713 56.0
TLS3_k127_6442620_8 PFAM Carbon starvation protein CstA K06200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 488.0
TLS3_k127_6442620_81 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000003812 51.0
TLS3_k127_6442620_84 Helix-turn-helix domain - - - 0.0001765 46.0
TLS3_k127_6442620_85 EamA-like transporter family - - - 0.0002649 53.0
TLS3_k127_6442620_9 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0000096,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006556,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009069,GO:0009108,GO:0009116,GO:0009119,GO:0009987,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0019752,GO:0030554,GO:0030955,GO:0031420,GO:0032553,GO:0032555,GO:0032559,GO:0033353,GO:0034641,GO:0035639,GO:0036094,GO:0042278,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046872,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901605,GO:1901657 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 468.0
TLS3_k127_6840490_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 4.47e-311 982.0
TLS3_k127_6840490_1 MutL protein - - - 2.43e-295 916.0
TLS3_k127_6840490_10 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 429.0
TLS3_k127_6840490_11 COG0168 Trk-type K transport systems, membrane components K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 426.0
TLS3_k127_6840490_12 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 409.0
TLS3_k127_6840490_13 Subtilase family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 378.0
TLS3_k127_6840490_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 364.0
TLS3_k127_6840490_15 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 357.0
TLS3_k127_6840490_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 357.0
TLS3_k127_6840490_17 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 356.0
TLS3_k127_6840490_18 Starch synthase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 365.0
TLS3_k127_6840490_19 TRK potassium uptake system protein (TrkA-2) K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000877 332.0
TLS3_k127_6840490_2 ATP-binding cassette protein, ChvD family - - - 7.963e-238 747.0
TLS3_k127_6840490_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 303.0
TLS3_k127_6840490_21 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 301.0
TLS3_k127_6840490_22 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003344 282.0
TLS3_k127_6840490_23 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001343 277.0
TLS3_k127_6840490_24 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000001104 248.0
TLS3_k127_6840490_25 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000001832 246.0
TLS3_k127_6840490_26 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000002464 232.0
TLS3_k127_6840490_27 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000001339 225.0
TLS3_k127_6840490_28 serine acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000478 214.0
TLS3_k127_6840490_29 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000001857 211.0
TLS3_k127_6840490_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 542.0
TLS3_k127_6840490_30 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000000001018 214.0
TLS3_k127_6840490_31 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000001652 218.0
TLS3_k127_6840490_32 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000002417 210.0
TLS3_k127_6840490_33 - - - - 0.0000000000000000000000000000000000000000000000004971 185.0
TLS3_k127_6840490_34 HIT domain K02503 - - 0.0000000000000000000000000000000000000000000004217 171.0
TLS3_k127_6840490_35 Methyltransferase domain - - - 0.000000000000000000000000000000000000000006579 164.0
TLS3_k127_6840490_36 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000008903 149.0
TLS3_k127_6840490_37 The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0009507,GO:0009536,GO:0009579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000004241 131.0
TLS3_k127_6840490_38 - - - - 0.000000000000000000000000000000004722 128.0
TLS3_k127_6840490_39 Ankyrin repeat - - - 0.0000000000000000000000000000009243 131.0
TLS3_k127_6840490_4 O-methyltransferase activity - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 539.0
TLS3_k127_6840490_40 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000009728 138.0
TLS3_k127_6840490_41 acetyltransferase - - - 0.0000000000000000000000000002012 127.0
TLS3_k127_6840490_42 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000846 117.0
TLS3_k127_6840490_43 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000875 115.0
TLS3_k127_6840490_45 - - - - 0.00000000000000000000000005111 117.0
TLS3_k127_6840490_47 Belongs to the bacterial histone-like protein family K03530,K05788 - - 0.00000000000000000000003328 103.0
TLS3_k127_6840490_48 membrane transporter protein K07090 - - 0.000000000000000000004975 103.0
TLS3_k127_6840490_49 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000003114 98.0
TLS3_k127_6840490_5 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 520.0
TLS3_k127_6840490_50 - - - - 0.0000000000000000003484 94.0
TLS3_k127_6840490_52 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000006072 68.0
TLS3_k127_6840490_53 myo-inosose-2 dehydratase activity K03079,K03335 - 4.2.1.44,5.1.3.22 0.0000000007132 69.0
TLS3_k127_6840490_54 YacP-like NYN domain K06962 - - 0.00000003744 66.0
TLS3_k127_6840490_55 Protein of unknown function (DUF1570) - - - 0.0000002368 63.0
TLS3_k127_6840490_56 - - - - 0.00005083 56.0
TLS3_k127_6840490_57 Uncharacterized protein conserved in bacteria (DUF2314) - - - 0.00006221 53.0
TLS3_k127_6840490_59 - - - - 0.0004237 48.0
TLS3_k127_6840490_6 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 505.0
TLS3_k127_6840490_7 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 476.0
TLS3_k127_6840490_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 441.0
TLS3_k127_6840490_9 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 432.0
TLS3_k127_6893954_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 337.0
TLS3_k127_6893954_1 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.000000000000000000000000000000000000000005502 161.0
TLS3_k127_6893954_10 Prokaryotic N-terminal methylation motif - - - 0.00000007537 63.0
TLS3_k127_6893954_11 efflux transmembrane transporter activity - - - 0.000048 56.0
TLS3_k127_6893954_12 COG2217 Cation transport ATPase K17686 GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0051179,GO:0051234 3.6.3.54 0.0002916 46.0
TLS3_k127_6893954_2 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000005883 159.0
TLS3_k127_6893954_3 PFAM transcriptional regulator PadR family protein - - - 0.00000000000000000000000000002243 121.0
TLS3_k127_6893954_4 Membrane-bound serine protease (ClpP class) - - - 0.000000000000000000000000008169 117.0
TLS3_k127_6893954_5 Collagen, type XVII, alpha K07603 GO:0002682,GO:0005575,GO:0005576,GO:0005604,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005886,GO:0005887,GO:0005911,GO:0007044,GO:0007155,GO:0007160,GO:0008150,GO:0008544,GO:0009888,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022610,GO:0030054,GO:0030055,GO:0030056,GO:0031012,GO:0031224,GO:0031226,GO:0031581,GO:0031589,GO:0031974,GO:0032502,GO:0034329,GO:0034330,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0048583,GO:0048856,GO:0050776,GO:0050789,GO:0062023,GO:0065007,GO:0070013,GO:0071840,GO:0071944 - 0.00000000000000000000251 106.0
TLS3_k127_6893954_6 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000146 102.0
TLS3_k127_6893954_7 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.0000000001147 76.0
TLS3_k127_6893954_8 domain, Protein K11904,K12132 - 2.7.11.1 0.0000000003799 67.0
TLS3_k127_6893954_9 Protein of unknown function (DUF1559) - - - 0.0000000008751 70.0
TLS3_k127_7055227_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1463.0
TLS3_k127_7055227_1 Methionine synthase K00548 - 2.1.1.13 0.0 1110.0
TLS3_k127_7055227_10 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 404.0
TLS3_k127_7055227_11 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 415.0
TLS3_k127_7055227_12 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 396.0
TLS3_k127_7055227_13 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 415.0
TLS3_k127_7055227_14 Major royal jelly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 359.0
TLS3_k127_7055227_15 dUTPase K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 319.0
TLS3_k127_7055227_16 PFAM glycoside hydrolase, family 10 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 337.0
TLS3_k127_7055227_17 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 320.0
TLS3_k127_7055227_18 ABC-type multidrug transport system ATPase and permease K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008515 321.0
TLS3_k127_7055227_19 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001278 273.0
TLS3_k127_7055227_2 PFAM Glu Leu Phe Val dehydrogenase K15371 - 1.4.1.2 9.927e-292 927.0
TLS3_k127_7055227_20 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002446 276.0
TLS3_k127_7055227_21 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000002244 269.0
TLS3_k127_7055227_22 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001603 256.0
TLS3_k127_7055227_23 Domain of unknown function (DUF4173) - - - 0.00000000000000000000000000000000000000000000000000000000000000000003387 251.0
TLS3_k127_7055227_24 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000151 231.0
TLS3_k127_7055227_25 N-terminal domain of unknown function (DUF4140) - - - 0.0000000000000000000000000000000000000000000000000000000000003258 233.0
TLS3_k127_7055227_26 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000007312 221.0
TLS3_k127_7055227_27 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000007088 208.0
TLS3_k127_7055227_28 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000001408 218.0
TLS3_k127_7055227_29 riboflavin biosynthesis protein K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000001438 215.0
TLS3_k127_7055227_3 glycyl-tRNA aminoacylation K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 8.039e-217 685.0
TLS3_k127_7055227_30 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000009735 213.0
TLS3_k127_7055227_31 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000002147 198.0
TLS3_k127_7055227_32 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000000000001361 188.0
TLS3_k127_7055227_33 phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000001577 191.0
TLS3_k127_7055227_34 Protein of unknown function (DUF1428) - - - 0.00000000000000000000000000000000000000000002378 165.0
TLS3_k127_7055227_35 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000297 159.0
TLS3_k127_7055227_36 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.000000000000000000000000000000000000000005385 166.0
TLS3_k127_7055227_37 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000001503 170.0
TLS3_k127_7055227_38 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000003738 157.0
TLS3_k127_7055227_39 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000003811 152.0
TLS3_k127_7055227_4 GTP-binding protein TypA K06207 - - 3.049e-212 676.0
TLS3_k127_7055227_41 Methyltransferase, chemotaxis proteins - - - 0.00000000000000000000000000003627 129.0
TLS3_k127_7055227_43 Polymer-forming cytoskeletal - - - 0.0000000000000000000000001775 111.0
TLS3_k127_7055227_45 Protein of unknown function (DUF1294) - - - 0.00000000000000000008614 91.0
TLS3_k127_7055227_46 Carbohydrate esterase family 3 protein - - - 0.0000000000000000008147 100.0
TLS3_k127_7055227_47 SLBB domain K02237 - - 0.0000000000001004 77.0
TLS3_k127_7055227_49 PFAM periplasmic binding protein K02016 - - 0.000000000007511 76.0
TLS3_k127_7055227_5 COG0210 Superfamily I DNA and RNA K03657 - 3.6.4.12 4.626e-207 673.0
TLS3_k127_7055227_50 RESPONSE REGULATOR receiver - - - 0.0000000001738 67.0
TLS3_k127_7055227_52 COG0784 FOG CheY-like receiver - - - 0.000001879 56.0
TLS3_k127_7055227_53 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00001555 56.0
TLS3_k127_7055227_6 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 613.0
TLS3_k127_7055227_7 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 563.0
TLS3_k127_7055227_8 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 469.0
TLS3_k127_7055227_9 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 454.0
TLS3_k127_7087001_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 524.0
TLS3_k127_7087001_1 peptide catabolic process - - - 0.000004993 57.0
TLS3_k127_715119_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.429e-240 762.0
TLS3_k127_715119_1 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 4.196e-199 636.0
TLS3_k127_715119_10 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001264 281.0
TLS3_k127_715119_11 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000001293 288.0
TLS3_k127_715119_12 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000002013 218.0
TLS3_k127_715119_13 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000002783 212.0
TLS3_k127_715119_14 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000002411 214.0
TLS3_k127_715119_15 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids - - - 0.0000000000000000000000000000000000000000000000000008627 196.0
TLS3_k127_715119_16 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02768,K02806 - 2.7.1.202 0.000000000000000000000000000000000000004092 151.0
TLS3_k127_715119_17 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.0000000000000000000000000000000000001674 151.0
TLS3_k127_715119_18 Thioesterase superfamily - - - 0.00000000000000000001653 100.0
TLS3_k127_715119_19 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000006921 101.0
TLS3_k127_715119_2 Aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 579.0
TLS3_k127_715119_20 Phosphocarrier protein HPr K08485,K11189 - - 0.000000000000000008304 86.0
TLS3_k127_715119_21 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000001537 78.0
TLS3_k127_715119_22 - - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009507,GO:0009509,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009575,GO:0009579,GO:0009611,GO:0009628,GO:0009642,GO:0009644,GO:0009765,GO:0009941,GO:0009987,GO:0010206,GO:0010207,GO:0015979,GO:0016020,GO:0016043,GO:0019538,GO:0019684,GO:0019898,GO:0022607,GO:0030091,GO:0031090,GO:0031967,GO:0031969,GO:0031975,GO:0031976,GO:0031984,GO:0034357,GO:0034622,GO:0035448,GO:0042170,GO:0042651,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0055035,GO:0065003,GO:0071704,GO:0071840,GO:1901564 - 0.00000006489 65.0
TLS3_k127_715119_23 PDZ domain (Also known as DHR or GLGF) - - - 0.000001387 61.0
TLS3_k127_715119_24 Domain of unknown function (DUF4340) - - - 0.0002788 53.0
TLS3_k127_715119_25 transport system involved in gliding motility, auxiliary component - - - 0.0008782 53.0
TLS3_k127_715119_3 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 462.0
TLS3_k127_715119_4 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 402.0
TLS3_k127_715119_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 385.0
TLS3_k127_715119_6 Heavy metal translocating P-type atpase K01534,K17686 - 3.6.3.3,3.6.3.5,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 348.0
TLS3_k127_715119_7 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 344.0
TLS3_k127_715119_8 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002645 291.0
TLS3_k127_715119_9 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002108 287.0
TLS3_k127_7233868_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1298.0
TLS3_k127_7233868_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 1.658e-276 867.0
TLS3_k127_7233868_10 hydroxylamine reductase activity K00528,K02287,K02641,K15511 GO:0005575,GO:0005622,GO:0005623,GO:0009579,GO:0016020,GO:0034357,GO:0042651,GO:0044424,GO:0044436,GO:0044464 1.14.13.208,1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 306.0
TLS3_k127_7233868_11 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 295.0
TLS3_k127_7233868_12 Oxygen tolerance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007192 296.0
TLS3_k127_7233868_13 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004764 253.0
TLS3_k127_7233868_14 MatE - - - 0.0000000000000000000000000000000000000000000000000000001231 217.0
TLS3_k127_7233868_15 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000005315 194.0
TLS3_k127_7233868_16 tRNA rRNA methyltransferase - - - 0.0000000000000000000000000000000000000000000000004391 189.0
TLS3_k127_7233868_17 ECF sigma factor - - - 0.00000000000000000000000000000000000000000003892 167.0
TLS3_k127_7233868_18 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000003127 164.0
TLS3_k127_7233868_19 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000003898 154.0
TLS3_k127_7233868_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 491.0
TLS3_k127_7233868_20 DinB superfamily - - - 0.000000000000000000000000000000000000001588 153.0
TLS3_k127_7233868_21 FG-GAP repeat - - - 0.00000000000000000000000000000000001193 144.0
TLS3_k127_7233868_22 Phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.000000000000000000000000000000001473 141.0
TLS3_k127_7233868_23 - K07164,K22391 - 3.5.4.16 0.000000000000000000000000000000005404 138.0
TLS3_k127_7233868_24 COG0607 Rhodanese-related sulfurtransferase - - - 0.00000000000000000000000000000004322 129.0
TLS3_k127_7233868_25 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000003074 132.0
TLS3_k127_7233868_26 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000008966 122.0
TLS3_k127_7233868_27 response regulator K11624 - - 0.000000000000000000000001652 109.0
TLS3_k127_7233868_28 - - - - 0.0000000000000000000000181 113.0
TLS3_k127_7233868_29 FG-GAP repeat - - - 0.00000000000000000000002469 117.0
TLS3_k127_7233868_3 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 462.0
TLS3_k127_7233868_30 PA14 domain - - - 0.0000000000000000000000533 113.0
TLS3_k127_7233868_31 Oxygen tolerance - - - 0.00000000000000000001979 101.0
TLS3_k127_7233868_32 regulatory protein RecX K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000002289 66.0
TLS3_k127_7233868_33 von Willebrand factor (vWF) type A domain - - - 0.00000002311 66.0
TLS3_k127_7233868_34 Phosphoribosyl transferase domain K00764 - 2.4.2.14 0.0000000713 64.0
TLS3_k127_7233868_4 cysteine synthase K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 430.0
TLS3_k127_7233868_5 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 428.0
TLS3_k127_7233868_6 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 334.0
TLS3_k127_7233868_7 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 329.0
TLS3_k127_7233868_8 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 325.0
TLS3_k127_7233868_9 peptide catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 332.0
TLS3_k127_7331330_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 6.689e-239 754.0
TLS3_k127_7331330_1 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 6.204e-210 672.0
TLS3_k127_7331330_10 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 406.0
TLS3_k127_7331330_11 ATPase associated with K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 381.0
TLS3_k127_7331330_12 Tryptophan 2,3-dioxygenase K00453 - 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009725 375.0
TLS3_k127_7331330_13 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008062 347.0
TLS3_k127_7331330_14 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 338.0
TLS3_k127_7331330_15 PFAM amidohydrolase K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 328.0
TLS3_k127_7331330_16 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 307.0
TLS3_k127_7331330_17 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001643 293.0
TLS3_k127_7331330_18 tRNA nucleotidyltransferase poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000004302 276.0
TLS3_k127_7331330_19 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00226,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001138 270.0
TLS3_k127_7331330_2 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 574.0
TLS3_k127_7331330_20 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008411 273.0
TLS3_k127_7331330_21 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000001226 266.0
TLS3_k127_7331330_22 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002272 257.0
TLS3_k127_7331330_23 von Willebrand factor type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001101 271.0
TLS3_k127_7331330_24 extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000002109 244.0
TLS3_k127_7331330_25 RING finger protein - - - 0.000000000000000000000000000000000000000000000000000000004018 226.0
TLS3_k127_7331330_26 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000004219 194.0
TLS3_k127_7331330_27 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000001407 186.0
TLS3_k127_7331330_28 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 GO:0000334,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009072,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009435,GO:0009987,GO:0016491,GO:0016701,GO:0016702,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034354,GO:0034627,GO:0034641,GO:0034654,GO:0042430,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0051213,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.13.11.6 0.00000000000000000000000000000000000000000000000002209 185.0
TLS3_k127_7331330_29 acetyltransferase K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000001215 175.0
TLS3_k127_7331330_3 Band 7 protein K07192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 553.0
TLS3_k127_7331330_30 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.000000000000000000000000000000000000000000001473 177.0
TLS3_k127_7331330_31 Bacterial Fe(2+) trafficking - - - 0.00000000000000000000000000000000000000000000499 172.0
TLS3_k127_7331330_32 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000512 153.0
TLS3_k127_7331330_33 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000007491 150.0
TLS3_k127_7331330_34 ATPase or kinase K06925 - - 0.0000000000000000000000000000000008745 138.0
TLS3_k127_7331330_35 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000002527 133.0
TLS3_k127_7331330_36 - - - - 0.00000000000000000000000000000001655 147.0
TLS3_k127_7331330_37 Domain of unknown function (DUF1905) - - - 0.000000000000000000000000000009788 126.0
TLS3_k127_7331330_38 Ankyrin repeat - - - 0.00000000000000000000000000001313 138.0
TLS3_k127_7331330_39 - - - - 0.0000000000000000000000000001161 122.0
TLS3_k127_7331330_4 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 516.0
TLS3_k127_7331330_40 NmrA-like family - - - 0.000000000000000000000000001679 128.0
TLS3_k127_7331330_42 - - - - 0.000000000000000000000001029 108.0
TLS3_k127_7331330_43 - - - - 0.00000000000000000000007567 108.0
TLS3_k127_7331330_44 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000003036 108.0
TLS3_k127_7331330_45 Zincin-like metallopeptidase - - - 0.000000000000000000003674 99.0
TLS3_k127_7331330_46 - - - - 0.000000000000000000005207 106.0
TLS3_k127_7331330_47 acetyltransferase - - - 0.0000000000000000005238 97.0
TLS3_k127_7331330_48 - - - - 0.000000000000000007876 93.0
TLS3_k127_7331330_49 Protein of unknown function (DUF1569) - - - 0.000000000000005964 82.0
TLS3_k127_7331330_5 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 491.0
TLS3_k127_7331330_50 response regulator K07689 - - 0.0000000000000133 82.0
TLS3_k127_7331330_51 chaperone-mediated protein folding - - - 0.0000000000001088 74.0
TLS3_k127_7331330_52 von Willebrand factor type A domain K07114 - - 0.0000000000001445 84.0
TLS3_k127_7331330_53 - - - - 0.00000000000131 71.0
TLS3_k127_7331330_54 diguanylate cyclase - - - 0.000000000008565 72.0
TLS3_k127_7331330_55 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000001168 74.0
TLS3_k127_7331330_56 nuclear chromosome segregation - - - 0.000000004466 69.0
TLS3_k127_7331330_57 Protein involved in outer membrane biogenesis - - - 0.0000001073 66.0
TLS3_k127_7331330_58 Endonuclease/Exonuclease/phosphatase family - - - 0.0000003764 62.0
TLS3_k127_7331330_59 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000004496 55.0
TLS3_k127_7331330_6 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 483.0
TLS3_k127_7331330_60 - - - - 0.000004904 51.0
TLS3_k127_7331330_61 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.000005367 48.0
TLS3_k127_7331330_63 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00007396 53.0
TLS3_k127_7331330_64 Peptidase family S49 K04773,K04774 - - 0.0001143 54.0
TLS3_k127_7331330_65 Dienelactone hydrolase family K06889 GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0034338,GO:0052689 - 0.0001728 53.0
TLS3_k127_7331330_66 function (DUF490) K09800 - - 0.0001793 56.0
TLS3_k127_7331330_67 Belongs to the anti-sigma-factor antagonist family - - - 0.0003777 48.0
TLS3_k127_7331330_68 MlaD protein K02067 - - 0.0005676 52.0
TLS3_k127_7331330_7 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 442.0
TLS3_k127_7331330_8 Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid K00486 - 1.14.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 424.0
TLS3_k127_7331330_9 aspartate kinase, monofunctional class K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 414.0
TLS3_k127_738660_0 with chaperone activity ATP-binding K03696 - - 0.0 1298.0
TLS3_k127_738660_1 Cytochrome c554 and c-prime - - - 0.0 1076.0
TLS3_k127_738660_10 belongs to the thioredoxin family K03671,K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 5.997e-194 623.0
TLS3_k127_738660_100 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000001443 218.0
TLS3_k127_738660_101 Zn-dependent dipeptidase, microsomal dipeptidase K01273,K01274 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000002167 218.0
TLS3_k127_738660_102 PFAM Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000008577 216.0
TLS3_k127_738660_103 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000001214 215.0
TLS3_k127_738660_104 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000001507 224.0
TLS3_k127_738660_105 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000001579 224.0
TLS3_k127_738660_106 PFAM Cytochrome c, class I K08738 - - 0.000000000000000000000000000000000000000000000000000000002931 218.0
TLS3_k127_738660_107 tRNA pseudouridine synthase K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000006341 207.0
TLS3_k127_738660_108 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000009003 212.0
TLS3_k127_738660_109 TIGRFAM cytochrome c nitrate reductase, small subunit K15876 - - 0.000000000000000000000000000000000000000000000000000003317 195.0
TLS3_k127_738660_11 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 602.0
TLS3_k127_738660_110 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000003584 209.0
TLS3_k127_738660_111 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000005731 199.0
TLS3_k127_738660_112 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000001003 201.0
TLS3_k127_738660_113 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000002501 201.0
TLS3_k127_738660_114 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000006233 198.0
TLS3_k127_738660_115 - - - - 0.0000000000000000000000000000000000000000000000000002834 195.0
TLS3_k127_738660_116 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000004617 186.0
TLS3_k127_738660_117 TIGRFAM DNA binding domain protein, excisionase family K22491 - - 0.0000000000000000000000000000000000000000000000001071 188.0
TLS3_k127_738660_118 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000003678 183.0
TLS3_k127_738660_119 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.000000000000000000000000000000000000000000000002999 195.0
TLS3_k127_738660_12 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 580.0
TLS3_k127_738660_120 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000003788 183.0
TLS3_k127_738660_121 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000001457 179.0
TLS3_k127_738660_122 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000002666 187.0
TLS3_k127_738660_123 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000003576 181.0
TLS3_k127_738660_124 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000007734 169.0
TLS3_k127_738660_125 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000004496 167.0
TLS3_k127_738660_127 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX K17759 - 5.1.99.6 0.0000000000000000000000000000000000000000000198 173.0
TLS3_k127_738660_128 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000002794 180.0
TLS3_k127_738660_129 Redoxin - - - 0.000000000000000000000000000000000000000009982 162.0
TLS3_k127_738660_13 Cystathionine beta-synthase K01697 - 4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 559.0
TLS3_k127_738660_130 Trehalose utilisation - - - 0.00000000000000000000000000000000000000006365 169.0
TLS3_k127_738660_131 Peptidase family M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000001829 168.0
TLS3_k127_738660_132 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000001998 158.0
TLS3_k127_738660_133 Pfam:DUF59 K02612 - - 0.000000000000000000000000000000000000003759 151.0
TLS3_k127_738660_134 Lipid A 3-O-deacylase (PagL) - - - 0.00000000000000000000000000000000000001773 153.0
TLS3_k127_738660_135 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000001221 148.0
TLS3_k127_738660_136 ANTAR K22010 GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 - 0.000000000000000000000000000000000001441 148.0
TLS3_k127_738660_137 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.00000000000000000000000000000000000555 147.0
TLS3_k127_738660_138 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000841 151.0
TLS3_k127_738660_139 Ser Thr phosphatase family protein K07098 - - 0.0000000000000000000000000000000004045 143.0
TLS3_k127_738660_14 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 544.0
TLS3_k127_738660_140 ECF sigma factor - - - 0.0000000000000000000000000000000004547 147.0
TLS3_k127_738660_141 Phosphate-selective porin O and P - - - 0.0000000000000000000000000000000006903 148.0
TLS3_k127_738660_142 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03086,K03093 - - 0.000000000000000000000000000000001226 148.0
TLS3_k127_738660_143 SOUL heme-binding protein - - - 0.000000000000000000000000000000001889 141.0
TLS3_k127_738660_144 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000001028 147.0
TLS3_k127_738660_145 protein methyltransferase activity K11434,K15984,K20421 - 2.1.1.242,2.1.1.303,2.1.1.319 0.00000000000000000000000000000001251 139.0
TLS3_k127_738660_146 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000004893 134.0
TLS3_k127_738660_147 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000003009 140.0
TLS3_k127_738660_148 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000003655 139.0
TLS3_k127_738660_15 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 541.0
TLS3_k127_738660_150 Outer membrane efflux protein K15725 - - 0.00000000000000000000000000002214 134.0
TLS3_k127_738660_152 Putative tRNA binding domain K01874 - 6.1.1.10 0.0000000000000000000000000001939 119.0
TLS3_k127_738660_153 PFAM Cytochrome c, class I K08738 - - 0.0000000000000000000000000005569 122.0
TLS3_k127_738660_154 to be involved in C-type cytochrome biogenesis K04084 - 1.8.1.8 0.0000000000000000000000000006651 124.0
TLS3_k127_738660_155 UbiA prenyltransferase family - - - 0.000000000000000000000000001161 123.0
TLS3_k127_738660_156 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000002864 115.0
TLS3_k127_738660_157 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000004748 119.0
TLS3_k127_738660_158 Protein of unknown function DUF86 - - - 0.0000000000000000000000002218 110.0
TLS3_k127_738660_159 domain, Protein - - - 0.0000000000000000000000008771 122.0
TLS3_k127_738660_16 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 535.0
TLS3_k127_738660_160 - - - - 0.0000000000000000000000009709 110.0
TLS3_k127_738660_161 Phosphate-selective porin O and P - - - 0.000000000000000000000001121 119.0
TLS3_k127_738660_162 Nucleotidyltransferase domain K07075 - - 0.000000000000000000000004797 105.0
TLS3_k127_738660_163 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000001214 106.0
TLS3_k127_738660_164 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000001916 108.0
TLS3_k127_738660_165 - - - - 0.00000000000000000000002523 113.0
TLS3_k127_738660_166 chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.00000000000000000000006913 106.0
TLS3_k127_738660_168 Methyltransferase domain - - - 0.00000000000000000000039 104.0
TLS3_k127_738660_17 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009705 537.0
TLS3_k127_738660_170 - - - - 0.0000000000000000000007315 99.0
TLS3_k127_738660_171 MazG nucleotide pyrophosphohydrolase domain - - - 0.000000000000000000001532 98.0
TLS3_k127_738660_172 - - - - 0.00000000000000000007853 93.0
TLS3_k127_738660_173 rRNA processing K02834 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000008875 98.0
TLS3_k127_738660_174 PFAM Prenyltransferase squalene oxidase - - - 0.0000000000000000002439 101.0
TLS3_k127_738660_175 Cold-shock DNA-binding domain protein K03704 - - 0.0000000000000000006866 90.0
TLS3_k127_738660_176 Protein conserved in bacteria - - - 0.000000000000000001379 96.0
TLS3_k127_738660_177 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000007886 95.0
TLS3_k127_738660_178 NifU-like domain - - - 0.000000000000000008997 87.0
TLS3_k127_738660_179 - - - - 0.0000000000000001354 91.0
TLS3_k127_738660_18 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 531.0
TLS3_k127_738660_180 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000001175 83.0
TLS3_k127_738660_181 Domain of unknown function (DUF378) K09779 - - 0.000000000000001725 78.0
TLS3_k127_738660_182 Peptidase family C25 - - - 0.00000000000001539 87.0
TLS3_k127_738660_183 COG0457 FOG TPR repeat - - - 0.00000000000003116 88.0
TLS3_k127_738660_185 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000004481 75.0
TLS3_k127_738660_187 - - - - 0.00000000000009461 80.0
TLS3_k127_738660_188 PRC-barrel domain - - - 0.0000000000002007 83.0
TLS3_k127_738660_189 Protein of unknown function (DUF2752) - - - 0.000000000002195 73.0
TLS3_k127_738660_19 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 544.0
TLS3_k127_738660_191 PFAM CBS domain K07182 - - 0.00000000001876 72.0
TLS3_k127_738660_192 Pectate lyase superfamily protein - - - 0.0000000000213 77.0
TLS3_k127_738660_194 self proteolysis - - - 0.00000000005773 76.0
TLS3_k127_738660_195 ABC-type amino acid transport signal transduction systems periplasmic component domain - - - 0.000000000132 70.0
TLS3_k127_738660_196 - - - - 0.0000000001465 68.0
TLS3_k127_738660_197 Phosphorylase superfamily - - - 0.0000000002894 71.0
TLS3_k127_738660_198 Glycosyl transferase family 41 - - - 0.0000000003223 72.0
TLS3_k127_738660_199 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000007098 67.0
TLS3_k127_738660_2 peptidyl-tyrosine sulfation - - - 0.0 1036.0
TLS3_k127_738660_20 adenylate kinase activity K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 518.0
TLS3_k127_738660_200 best DB hits PFAM PF00114 - - - 0.000000001351 70.0
TLS3_k127_738660_201 energy transducer activity K03110,K03832 - - 0.000000002695 68.0
TLS3_k127_738660_202 Thrombospondin type 3 repeat - - - 0.000000005227 68.0
TLS3_k127_738660_203 Conserved repeat domain - - - 0.0000000463 66.0
TLS3_k127_738660_205 TIGRFAM prepilin-type N-terminal cleavage methylation domain - - - 0.0000002447 61.0
TLS3_k127_738660_207 long-chain fatty acid transport protein - - - 0.000001412 59.0
TLS3_k127_738660_208 PFAM Phosphate-selective porin O and P - - - 0.000002098 60.0
TLS3_k127_738660_209 - - - - 0.000002827 59.0
TLS3_k127_738660_21 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00819 - 2.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 519.0
TLS3_k127_738660_212 Prokaryotic N-terminal methylation motif - - - 0.000008723 58.0
TLS3_k127_738660_214 TIGRFAM prepilin-type N-terminal cleavage methylation domain - - - 0.00001694 56.0
TLS3_k127_738660_215 Putative regulatory protein - - - 0.00003242 49.0
TLS3_k127_738660_216 Glycosyl transferase 4-like domain K02844 - - 0.00004514 55.0
TLS3_k127_738660_218 Tetratricopeptide repeat K12132 - 2.7.11.1 0.00008646 55.0
TLS3_k127_738660_22 Cystathionine beta-lyase K01758,K01760 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004121,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.4.1.1,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 511.0
TLS3_k127_738660_220 Protein of unknown function (DUF1573) - - - 0.0001466 53.0
TLS3_k127_738660_221 FMN binding - - - 0.0002179 51.0
TLS3_k127_738660_222 - - - - 0.0002535 50.0
TLS3_k127_738660_23 AP endonuclease family 2 C terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 501.0
TLS3_k127_738660_24 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008545 506.0
TLS3_k127_738660_25 PFAM Carbamoyltransferase K00612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 500.0
TLS3_k127_738660_26 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 486.0
TLS3_k127_738660_27 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 466.0
TLS3_k127_738660_28 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 464.0
TLS3_k127_738660_29 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 456.0
TLS3_k127_738660_3 PFAM Cytochrome c, class I K08738 - - 5.168e-281 888.0
TLS3_k127_738660_30 dehydrogenases and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 455.0
TLS3_k127_738660_31 Belongs to the sulfate adenylyltransferase family K00958,K13811 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 454.0
TLS3_k127_738660_32 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 442.0
TLS3_k127_738660_33 PFAM 3-dehydroquinate synthase K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 441.0
TLS3_k127_738660_34 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 433.0
TLS3_k127_738660_35 and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 437.0
TLS3_k127_738660_36 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 437.0
TLS3_k127_738660_37 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 435.0
TLS3_k127_738660_38 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 419.0
TLS3_k127_738660_39 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 424.0
TLS3_k127_738660_4 Glutamine synthetase type III K01915 - 6.3.1.2 1.063e-267 842.0
TLS3_k127_738660_40 with the TIM-barrel fold K07051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 410.0
TLS3_k127_738660_41 metal ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 414.0
TLS3_k127_738660_42 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 430.0
TLS3_k127_738660_43 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 406.0
TLS3_k127_738660_44 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 415.0
TLS3_k127_738660_45 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 398.0
TLS3_k127_738660_46 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 385.0
TLS3_k127_738660_47 PFAM ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 379.0
TLS3_k127_738660_48 dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 379.0
TLS3_k127_738660_49 PDZ domain (Also known as DHR or GLGF) K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 373.0
TLS3_k127_738660_5 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.542e-247 778.0
TLS3_k127_738660_50 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 370.0
TLS3_k127_738660_51 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 366.0
TLS3_k127_738660_52 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 362.0
TLS3_k127_738660_53 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 353.0
TLS3_k127_738660_54 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 348.0
TLS3_k127_738660_55 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 345.0
TLS3_k127_738660_56 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 346.0
TLS3_k127_738660_57 Selenocysteine lyase K04127 - 5.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 340.0
TLS3_k127_738660_58 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 347.0
TLS3_k127_738660_59 PFAM Dehydrogenase, E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 336.0
TLS3_k127_738660_6 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 2.822e-234 771.0
TLS3_k127_738660_60 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 336.0
TLS3_k127_738660_61 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 335.0
TLS3_k127_738660_62 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 331.0
TLS3_k127_738660_63 translation initiation factor activity K03496,K09000 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 329.0
TLS3_k127_738660_64 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 320.0
TLS3_k127_738660_65 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 325.0
TLS3_k127_738660_66 SPTR Glycosyl transferase, group 1 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 317.0
TLS3_k127_738660_67 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 312.0
TLS3_k127_738660_68 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 314.0
TLS3_k127_738660_69 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 307.0
TLS3_k127_738660_7 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 5.109e-222 711.0
TLS3_k127_738660_70 metallophosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 308.0
TLS3_k127_738660_71 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 302.0
TLS3_k127_738660_72 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009911 312.0
TLS3_k127_738660_73 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 299.0
TLS3_k127_738660_74 Adenylylsulphate kinase K00955 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 297.0
TLS3_k127_738660_75 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 297.0
TLS3_k127_738660_76 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000137 294.0
TLS3_k127_738660_77 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001158 287.0
TLS3_k127_738660_78 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002789 274.0
TLS3_k127_738660_79 Bacterial transferase hexapeptide (six repeats) K02617,K08279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006922 270.0
TLS3_k127_738660_8 phenylacetic acid degradation protein paaN - - - 1.65e-206 657.0
TLS3_k127_738660_80 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000002378 274.0
TLS3_k127_738660_81 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000007599 272.0
TLS3_k127_738660_82 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000271 272.0
TLS3_k127_738660_83 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000007633 263.0
TLS3_k127_738660_85 isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001199 256.0
TLS3_k127_738660_86 involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002536 259.0
TLS3_k127_738660_87 PFAM Bacterial transferase hexapeptide (three repeats) K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000006214 251.0
TLS3_k127_738660_88 Alternative locus ID - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001773 263.0
TLS3_k127_738660_89 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000005992 259.0
TLS3_k127_738660_9 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 2.234e-206 652.0
TLS3_k127_738660_90 Responsible for synthesis of pseudouridine from uracil - - - 0.00000000000000000000000000000000000000000000000000000000000000000002798 239.0
TLS3_k127_738660_91 diguanylate cyclase activity K13069 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000001211 249.0
TLS3_k127_738660_92 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000001288 242.0
TLS3_k127_738660_93 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000002352 243.0
TLS3_k127_738660_94 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004397 243.0
TLS3_k127_738660_95 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000001829 232.0
TLS3_k127_738660_96 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000002374 237.0
TLS3_k127_738660_97 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 4.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000051 233.0
TLS3_k127_738660_98 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000001151 224.0
TLS3_k127_738660_99 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000002182 220.0
TLS3_k127_7482839_0 Prolyl oligopeptidase K01322 - 3.4.21.26 2.151e-316 982.0
TLS3_k127_7482839_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 426.0
TLS3_k127_7482839_10 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000003227 241.0
TLS3_k127_7482839_11 Squalene/phytoene synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005206 240.0
TLS3_k127_7482839_12 ergosterol biosynthetic process K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000002755 189.0
TLS3_k127_7482839_13 PEP-CTERM motif - - - 0.0000000000000000000000000000000000000000000000004535 184.0
TLS3_k127_7482839_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000608 136.0
TLS3_k127_7482839_15 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000319 139.0
TLS3_k127_7482839_16 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000006686 134.0
TLS3_k127_7482839_17 Pyruvate ferredoxin/flavodoxin oxidoreductase K00179,K04090 - 1.2.7.8 0.0000000000000000000000000006326 133.0
TLS3_k127_7482839_18 - - - - 0.0000000000000000000000004275 115.0
TLS3_k127_7482839_19 Domain of unknown function (DUF4082) - - - 0.00000000002169 72.0
TLS3_k127_7482839_2 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase K00322 - 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 413.0
TLS3_k127_7482839_20 Activator of hsp90 atpase 1 family protein - - - 0.0000000001939 67.0
TLS3_k127_7482839_21 - - - - 0.00002534 52.0
TLS3_k127_7482839_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 409.0
TLS3_k127_7482839_4 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 412.0
TLS3_k127_7482839_5 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 413.0
TLS3_k127_7482839_6 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009996 389.0
TLS3_k127_7482839_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 318.0
TLS3_k127_7482839_8 FAD dependent oxidoreductase K00514 - 1.3.5.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 312.0
TLS3_k127_7482839_9 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009822 302.0
TLS3_k127_7582794_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 7.257e-295 918.0
TLS3_k127_7582794_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.298e-291 910.0
TLS3_k127_7582794_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006207 577.0
TLS3_k127_7582794_100 Specifically methylates the guanosine in position 1516 of 16S rRNA K15984 - 2.1.1.242 0.0000000000000000000000000000000000001369 151.0
TLS3_k127_7582794_101 Predicted membrane protein (DUF2238) - - - 0.0000000000000000000000000000000000007499 147.0
TLS3_k127_7582794_102 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000004114 154.0
TLS3_k127_7582794_103 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000001371 149.0
TLS3_k127_7582794_104 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.0000000000000000000000000000000001862 144.0
TLS3_k127_7582794_105 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000005483 153.0
TLS3_k127_7582794_106 Glyoxalase-like domain K06996 - - 0.000000000000000000000000000000002198 139.0
TLS3_k127_7582794_107 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000003655 145.0
TLS3_k127_7582794_108 - - - - 0.00000000000000000000000000000005434 133.0
TLS3_k127_7582794_109 PFAM outer membrane efflux protein - - - 0.0000000000000000000000000000001819 141.0
TLS3_k127_7582794_11 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 554.0
TLS3_k127_7582794_110 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.0000000000000000000000000000001904 133.0
TLS3_k127_7582794_111 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000005042 121.0
TLS3_k127_7582794_112 - - - - 0.00000000000000000000000000001367 124.0
TLS3_k127_7582794_113 amine dehydrogenase activity K01179,K03333,K12287 - 1.1.3.6,3.2.1.4 0.00000000000000000000000000008925 136.0
TLS3_k127_7582794_114 - - - - 0.000000000000000000000000001019 119.0
TLS3_k127_7582794_115 Cytochrome C assembly protein - - - 0.0000000000000000000000001133 123.0
TLS3_k127_7582794_116 Regulatory protein, FmdB family - - - 0.0000000000000000000000001364 109.0
TLS3_k127_7582794_117 transferase activity, transferring glycosyl groups K08604,K20276 - 3.4.24.25 0.0000000000000000000000001997 125.0
TLS3_k127_7582794_118 23S rRNA-intervening sequence protein - - - 0.000000000000000000000001728 106.0
TLS3_k127_7582794_119 Putative ATP-dependant zinc protease - - - 0.00000000000000000000001499 108.0
TLS3_k127_7582794_12 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 521.0
TLS3_k127_7582794_120 Proprotein convertase P-domain - - - 0.00000000000000000000004924 117.0
TLS3_k127_7582794_121 Amidohydrolase family - - - 0.00000000000000000000006257 102.0
TLS3_k127_7582794_122 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.0000000000000000000002292 104.0
TLS3_k127_7582794_123 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000002454 100.0
TLS3_k127_7582794_124 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000003682 107.0
TLS3_k127_7582794_125 Protein of unknown function, DUF488 - - - 0.0000000000000000000005189 104.0
TLS3_k127_7582794_126 iron-regulated protein - - - 0.00000000000000000006741 102.0
TLS3_k127_7582794_127 COG1360 Flagellar motor protein K02557 - - 0.00000000000000000087 97.0
TLS3_k127_7582794_128 - - - - 0.00000000000000002872 89.0
TLS3_k127_7582794_129 peptide catabolic process - - - 0.00000000000000006624 94.0
TLS3_k127_7582794_13 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 548.0
TLS3_k127_7582794_130 - - - - 0.00000000000000008583 81.0
TLS3_k127_7582794_131 Beta-lactamase - - - 0.0000000000000007024 85.0
TLS3_k127_7582794_132 protein kinase activity K12132 - 2.7.11.1 0.000000000000006656 89.0
TLS3_k127_7582794_134 - - - - 0.00000000000008987 74.0
TLS3_k127_7582794_135 Protein of unknown function (DUF1778) - - - 0.00000000002404 70.0
TLS3_k127_7582794_136 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000001024 70.0
TLS3_k127_7582794_137 - - - - 0.0000000001461 66.0
TLS3_k127_7582794_139 Protein of unknown function (DUF1573) - - - 0.0000000004512 71.0
TLS3_k127_7582794_14 belongs to the lyase 1 family. Argininosuccinate lyase subfamily K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 516.0
TLS3_k127_7582794_142 Glycosyltransferase like family 2 - - - 0.000000008131 66.0
TLS3_k127_7582794_143 2'-5' RNA ligase superfamily K01975 - 3.1.4.58 0.00000003535 63.0
TLS3_k127_7582794_144 methyltransferase - - - 0.0000001355 62.0
TLS3_k127_7582794_146 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.0000192 55.0
TLS3_k127_7582794_147 Stress responsive A/B Barrel Domain - - - 0.00003169 54.0
TLS3_k127_7582794_148 Redoxin - - - 0.0000546 55.0
TLS3_k127_7582794_15 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 505.0
TLS3_k127_7582794_150 cytochrome c biogenesis protein - - - 0.0001624 55.0
TLS3_k127_7582794_152 - - - - 0.0007783 46.0
TLS3_k127_7582794_153 Belongs to the peptidase S8 family K01361,K08652 - 3.4.21.110,3.4.21.96 0.0009221 53.0
TLS3_k127_7582794_16 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 479.0
TLS3_k127_7582794_17 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 454.0
TLS3_k127_7582794_18 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 426.0
TLS3_k127_7582794_19 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 417.0
TLS3_k127_7582794_2 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 5.841e-255 822.0
TLS3_k127_7582794_20 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 421.0
TLS3_k127_7582794_21 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 414.0
TLS3_k127_7582794_22 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 413.0
TLS3_k127_7582794_23 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 421.0
TLS3_k127_7582794_24 Vault protein inter-alpha-trypsin domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 424.0
TLS3_k127_7582794_25 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009383 407.0
TLS3_k127_7582794_26 C-5 cytosine-specific DNA methylase K00558,K17398 - 2.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 402.0
TLS3_k127_7582794_27 Potassium uptake protein K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 402.0
TLS3_k127_7582794_28 ADP transmembrane transporter activity K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 399.0
TLS3_k127_7582794_29 Zinc-uptake complex component A periplasmic K11707 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 394.0
TLS3_k127_7582794_3 ABC-type transport system involved in lipoprotein release permease component K02004 - - 4.475e-248 792.0
TLS3_k127_7582794_30 Prokaryotic glutathione synthetase, ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 388.0
TLS3_k127_7582794_31 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 380.0
TLS3_k127_7582794_32 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 390.0
TLS3_k127_7582794_33 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 379.0
TLS3_k127_7582794_34 ATPases associated with a variety of cellular activities K11607,K11710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 356.0
TLS3_k127_7582794_35 Belongs to the ABC transporter superfamily K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 352.0
TLS3_k127_7582794_36 succinylglutamate desuccinylase aspartoacylase K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 353.0
TLS3_k127_7582794_37 Short chain fatty acid transporter K02106 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 360.0
TLS3_k127_7582794_38 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 355.0
TLS3_k127_7582794_39 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 361.0
TLS3_k127_7582794_4 Domain of unknown function (DUF5117) - - - 1.428e-230 744.0
TLS3_k127_7582794_40 abc transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 342.0
TLS3_k127_7582794_41 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 355.0
TLS3_k127_7582794_42 Prenyltransferase and squalene oxidase repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 347.0
TLS3_k127_7582794_43 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 350.0
TLS3_k127_7582794_44 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 346.0
TLS3_k127_7582794_45 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008666 340.0
TLS3_k127_7582794_46 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 333.0
TLS3_k127_7582794_47 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 337.0
TLS3_k127_7582794_48 iron dependent repressor K03709,K09819,K11708 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 334.0
TLS3_k127_7582794_49 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 319.0
TLS3_k127_7582794_5 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 4.083e-227 714.0
TLS3_k127_7582794_50 of the beta-lactamase K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 308.0
TLS3_k127_7582794_51 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 308.0
TLS3_k127_7582794_52 Sterol carrier protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 303.0
TLS3_k127_7582794_53 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 306.0
TLS3_k127_7582794_54 methylisocitrate lyase activity K03417 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046421,GO:0046459,GO:0046872,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 292.0
TLS3_k127_7582794_55 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 297.0
TLS3_k127_7582794_56 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 291.0
TLS3_k127_7582794_57 rna polymerase alpha K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 291.0
TLS3_k127_7582794_58 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002774 287.0
TLS3_k127_7582794_59 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004944 292.0
TLS3_k127_7582794_6 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 3.253e-206 649.0
TLS3_k127_7582794_60 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001354 296.0
TLS3_k127_7582794_61 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002895 286.0
TLS3_k127_7582794_62 typically periplasmic contain C-terminal PDZ domain K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003909 287.0
TLS3_k127_7582794_63 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001204 280.0
TLS3_k127_7582794_64 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000003789 271.0
TLS3_k127_7582794_65 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000008164 273.0
TLS3_k127_7582794_66 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000001302 265.0
TLS3_k127_7582794_67 oligopeptide transport system permease protein OppB K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000338 265.0
TLS3_k127_7582794_68 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001158 262.0
TLS3_k127_7582794_69 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009958 254.0
TLS3_k127_7582794_7 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 2.867e-205 666.0
TLS3_k127_7582794_70 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002082 253.0
TLS3_k127_7582794_71 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001024 274.0
TLS3_k127_7582794_72 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002822 262.0
TLS3_k127_7582794_73 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000008449 245.0
TLS3_k127_7582794_74 MASE1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000007496 262.0
TLS3_k127_7582794_75 Domain of unknown function (DUF4928) - - - 0.000000000000000000000000000000000000000000000000000000000000000002181 238.0
TLS3_k127_7582794_76 PDZ domain (Also known as DHR K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000003447 233.0
TLS3_k127_7582794_77 COG1108 ABC-type Mn2 Zn2 transport systems, permease components K02075,K11708,K11709 - - 0.000000000000000000000000000000000000000000000000000000000001032 222.0
TLS3_k127_7582794_78 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000001044 227.0
TLS3_k127_7582794_79 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000001106 241.0
TLS3_k127_7582794_8 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 2.347e-199 636.0
TLS3_k127_7582794_80 PFAM Multi antimicrobial extrusion protein MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000005796 228.0
TLS3_k127_7582794_81 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000005326 203.0
TLS3_k127_7582794_82 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000005666 210.0
TLS3_k127_7582794_83 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000403 211.0
TLS3_k127_7582794_84 COG1291 Flagellar motor component K02556 - - 0.000000000000000000000000000000000000000000000000000007267 199.0
TLS3_k127_7582794_85 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000004646 182.0
TLS3_k127_7582794_86 COG0657 Esterase lipase - - - 0.00000000000000000000000000000000000000000000003138 183.0
TLS3_k127_7582794_87 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000007707 196.0
TLS3_k127_7582794_88 Beta-lactamase class C - - - 0.000000000000000000000000000000000000000000002863 185.0
TLS3_k127_7582794_89 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000006119 172.0
TLS3_k127_7582794_9 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 561.0
TLS3_k127_7582794_90 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000002588 173.0
TLS3_k127_7582794_91 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000003267 167.0
TLS3_k127_7582794_92 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000003307 169.0
TLS3_k127_7582794_93 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000006281 166.0
TLS3_k127_7582794_94 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000002808 158.0
TLS3_k127_7582794_95 May nick specific sequences that contain T G mispairs resulting from m5C-deamination K07458 - - 0.0000000000000000000000000000000000000002168 153.0
TLS3_k127_7582794_96 domain protein - - - 0.0000000000000000000000000000000000000009798 172.0
TLS3_k127_7582794_97 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000004493 154.0
TLS3_k127_7582794_98 Response regulator receiver - - - 0.00000000000000000000000000000000000001751 152.0
TLS3_k127_7582794_99 Iron dependent repressor, N-terminal DNA binding domain K11924 - - 0.00000000000000000000000000000000000002675 147.0
TLS3_k127_7823545_0 Hydantoinase/oxoprolinase K01469,K01473 - 3.5.2.14,3.5.2.9 0.0 1155.0
TLS3_k127_7823545_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 563.0
TLS3_k127_7823545_10 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 379.0
TLS3_k127_7823545_11 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 347.0
TLS3_k127_7823545_12 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 317.0
TLS3_k127_7823545_13 flagellar hook-associated protein K02396 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 304.0
TLS3_k127_7823545_14 Transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002684 262.0
TLS3_k127_7823545_15 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000003383 246.0
TLS3_k127_7823545_16 sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000005771 246.0
TLS3_k127_7823545_17 YmdB-like protein K02029,K02030,K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.000000000000000000000000000000000000000000000000000000000000000001723 236.0
TLS3_k127_7823545_18 Di-haem oxidoreductase, putative peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000005158 244.0
TLS3_k127_7823545_19 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000005519 199.0
TLS3_k127_7823545_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 563.0
TLS3_k127_7823545_20 Domain of unknown function (DUF4162) - - - 0.000000000000000000000000000000000000000000000002056 186.0
TLS3_k127_7823545_21 peptidyl-prolyl cis-trans isomerase activity K03769,K07533,K20074 - 3.1.3.16,5.2.1.8 0.000000000000000000000000000000000000000000003366 178.0
TLS3_k127_7823545_22 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.00000000000000000000000000000000000000000001026 179.0
TLS3_k127_7823545_23 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000001343 178.0
TLS3_k127_7823545_24 Permease YjgP YjgQ family K11720 - - 0.000000000000000000000000000000000000001502 161.0
TLS3_k127_7823545_25 PFAM Endonuclease Exonuclease phosphatase K07004 - - 0.000000000000000000000000000000005448 151.0
TLS3_k127_7823545_26 regulation of canonical Wnt signaling pathway involved in osteoblast differentiation - - - 0.0000000000000000000000000000002544 145.0
TLS3_k127_7823545_27 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.0000000000000000000000000002209 121.0
TLS3_k127_7823545_3 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 475.0
TLS3_k127_7823545_30 Hep Hag repeat protein - - - 0.00000000000000000000000005898 119.0
TLS3_k127_7823545_31 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.00000000000000000000008732 101.0
TLS3_k127_7823545_33 Cold shock protein K03704 - - 0.000000000000000000002944 94.0
TLS3_k127_7823545_34 HYR domain - - - 0.00000000000000000002363 109.0
TLS3_k127_7823545_35 Chaperone of endosialidase - - - 0.000000000002074 79.0
TLS3_k127_7823545_36 PFAM ASPIC and UnbV - - - 0.000000000003609 80.0
TLS3_k127_7823545_37 Belongs to the bacterial flagellin family K02397 - - 0.0000000001131 75.0
TLS3_k127_7823545_38 domain, Protein K11904,K12132 - 2.7.11.1 0.00000001238 63.0
TLS3_k127_7823545_39 Permease YjgP YjgQ family K07091 - - 0.0000004664 63.0
TLS3_k127_7823545_4 TIGRFAM ribonuclease, Rne Rng family K08300 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 492.0
TLS3_k127_7823545_40 Immunity protein 8 - - - 0.000002543 54.0
TLS3_k127_7823545_41 Fungalysin/Thermolysin Propeptide Motif - - - 0.000002734 63.0
TLS3_k127_7823545_42 Tetratricopeptide repeat - - - 0.0002409 53.0
TLS3_k127_7823545_5 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 471.0
TLS3_k127_7823545_6 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 436.0
TLS3_k127_7823545_7 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 427.0
TLS3_k127_7823545_8 Belongs to the peptidase S1B family K01337 - 3.4.21.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 429.0
TLS3_k127_7823545_9 PDZ domain (Also known as DHR K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 393.0
TLS3_k127_7873953_0 Carbamoylphosphate synthase large subunit K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0 1463.0
TLS3_k127_7873953_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1192.0
TLS3_k127_7873953_10 Regulator of RNA terminal phosphate cyclase K14414 - - 1.11e-214 679.0
TLS3_k127_7873953_100 COG0382 4-hydroxybenzoate polyprenyltransferase and related K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000007991 221.0
TLS3_k127_7873953_102 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000002146 216.0
TLS3_k127_7873953_103 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000003276 216.0
TLS3_k127_7873953_104 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000016 215.0
TLS3_k127_7873953_105 - - - - 0.0000000000000000000000000000000000000000000000000000000001998 211.0
TLS3_k127_7873953_106 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000002007 229.0
TLS3_k127_7873953_107 Calcineurin-like phosphoesterase K06953 - - 0.0000000000000000000000000000000000000000000000000000000006738 209.0
TLS3_k127_7873953_108 - - - - 0.000000000000000000000000000000000000000000000000000000001327 222.0
TLS3_k127_7873953_109 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000003111 207.0
TLS3_k127_7873953_11 Methylmalonyl-CoA mutase K01848,K11942 - 5.4.99.13,5.4.99.2 2.771e-207 658.0
TLS3_k127_7873953_110 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000001846 204.0
TLS3_k127_7873953_111 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000004291 205.0
TLS3_k127_7873953_112 Major facilitator superfamily K05939,K08227 - 2.3.1.40,6.2.1.20 0.0000000000000000000000000000000000000000000000000000004773 211.0
TLS3_k127_7873953_113 domain, Protein K15125 - - 0.0000000000000000000000000000000000000000000000000000008075 222.0
TLS3_k127_7873953_114 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000004421 199.0
TLS3_k127_7873953_115 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000007759 196.0
TLS3_k127_7873953_116 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000001494 197.0
TLS3_k127_7873953_117 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000001958 202.0
TLS3_k127_7873953_118 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity K01770 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006720,GO:0006721,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0015994,GO:0015995,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.12 0.00000000000000000000000000000000000000000000000000005471 191.0
TLS3_k127_7873953_119 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000101 193.0
TLS3_k127_7873953_12 TROVE domain - - - 1.312e-203 646.0
TLS3_k127_7873953_120 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000001128 198.0
TLS3_k127_7873953_121 Periplasmic component of the Tol biopolymer transport K03641 - - 0.0000000000000000000000000000000000000000000000000001654 203.0
TLS3_k127_7873953_122 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000002325 193.0
TLS3_k127_7873953_123 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000281 190.0
TLS3_k127_7873953_124 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000003192 196.0
TLS3_k127_7873953_125 Polymorphic membrane protein Chlamydia - - - 0.000000000000000000000000000000000000000000000000000898 204.0
TLS3_k127_7873953_126 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000000006264 189.0
TLS3_k127_7873953_127 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000006911 196.0
TLS3_k127_7873953_128 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000007963 183.0
TLS3_k127_7873953_129 Rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000000000000000000000001065 183.0
TLS3_k127_7873953_13 Binding-protein-dependent transport system inner membrane component K02011 - - 5.164e-198 632.0
TLS3_k127_7873953_130 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000002512 193.0
TLS3_k127_7873953_131 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000002587 184.0
TLS3_k127_7873953_132 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000009319 177.0
TLS3_k127_7873953_133 - - - - 0.00000000000000000000000000000000000000000000002365 178.0
TLS3_k127_7873953_134 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000008218 180.0
TLS3_k127_7873953_135 Phosphate-selective porin O and P - - - 0.0000000000000000000000000000000000000000000001371 185.0
TLS3_k127_7873953_136 PFAM UvrB UvrC protein K08999 - - 0.0000000000000000000000000000000000000000000004737 175.0
TLS3_k127_7873953_137 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000000001527 168.0
TLS3_k127_7873953_138 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000008292 185.0
TLS3_k127_7873953_139 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000001588 166.0
TLS3_k127_7873953_14 Asparagine synthase - - - 5.404e-195 627.0
TLS3_k127_7873953_140 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000003549 161.0
TLS3_k127_7873953_141 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000001775 160.0
TLS3_k127_7873953_143 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000002534 159.0
TLS3_k127_7873953_144 PHP domain K04486 - 3.1.3.15 0.00000000000000000000000000000000000000003528 163.0
TLS3_k127_7873953_146 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000005034 164.0
TLS3_k127_7873953_147 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000008458 170.0
TLS3_k127_7873953_148 Thiopurine S-methyltransferase - - - 0.000000000000000000000000000000000000008557 153.0
TLS3_k127_7873953_149 FG-GAP repeat - - - 0.000000000000000000000000000000000000008578 167.0
TLS3_k127_7873953_15 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 608.0
TLS3_k127_7873953_150 - - - - 0.00000000000000000000000000000000000001494 165.0
TLS3_k127_7873953_151 Peptidase family M50 - - - 0.00000000000000000000000000000000000002271 152.0
TLS3_k127_7873953_152 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000003587 149.0
TLS3_k127_7873953_153 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000003741 158.0
TLS3_k127_7873953_154 transglutaminase domain protein - - - 0.00000000000000000000000000000000000005002 164.0
TLS3_k127_7873953_155 PFAM Metal-dependent phosphohydrolase, HD K21138 - 3.1.7.2 0.00000000000000000000000000000000000006826 147.0
TLS3_k127_7873953_156 Sodium:solute symporter family K03307 - - 0.0000000000000000000000000000000000004947 157.0
TLS3_k127_7873953_157 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000001026 147.0
TLS3_k127_7873953_158 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000002035 143.0
TLS3_k127_7873953_159 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) K02372 - 4.2.1.59 0.000000000000000000000000000000000002225 144.0
TLS3_k127_7873953_16 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 610.0
TLS3_k127_7873953_160 nuclear chromosome segregation - - - 0.00000000000000000000000000000000001296 158.0
TLS3_k127_7873953_161 PhoP regulatory network protein YrbL - - - 0.00000000000000000000000000000000001408 146.0
TLS3_k127_7873953_162 Fibronectin type III domain - - - 0.0000000000000000000000000000000001736 145.0
TLS3_k127_7873953_163 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.0000000000000000000000000000000003807 135.0
TLS3_k127_7873953_164 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000006816 148.0
TLS3_k127_7873953_165 IrrE N-terminal-like domain - - - 0.000000000000000000000000000000000747 134.0
TLS3_k127_7873953_166 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000001264 136.0
TLS3_k127_7873953_167 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000001555 142.0
TLS3_k127_7873953_168 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000001339 130.0
TLS3_k127_7873953_169 FG-GAP repeat - - - 0.000000000000000000000000000004236 139.0
TLS3_k127_7873953_17 Pfam:KaiC K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 601.0
TLS3_k127_7873953_170 PFAM Bacterial Ig-like domain (group 2) - - - 0.000000000000000000000000000007805 137.0
TLS3_k127_7873953_171 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000000008112 123.0
TLS3_k127_7873953_172 PFAM conserved - GO:0008150,GO:0009314,GO:0009628,GO:0050896 - 0.0000000000000000000000000002817 119.0
TLS3_k127_7873953_173 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000003033 123.0
TLS3_k127_7873953_174 - - - - 0.0000000000000000000000000003172 126.0
TLS3_k127_7873953_175 - - - - 0.0000000000000000000000000004447 114.0
TLS3_k127_7873953_176 pilus assembly protein K02662 - - 0.00000000000000000000000002542 123.0
TLS3_k127_7873953_177 BlaR1 peptidase M56 - - - 0.00000000000000000000000003923 121.0
TLS3_k127_7873953_178 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000004441 121.0
TLS3_k127_7873953_179 - - - - 0.0000000000000000000000001491 115.0
TLS3_k127_7873953_18 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 595.0
TLS3_k127_7873953_180 PFAM SWIM zinc finger - - - 0.0000000000000000000000001619 118.0
TLS3_k127_7873953_181 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000002252 107.0
TLS3_k127_7873953_182 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) K02372 - 4.2.1.59 0.00000000000000000000000166 108.0
TLS3_k127_7873953_183 Protein of unknown function (DUF3800) - - - 0.000000000000000000000002287 117.0
TLS3_k127_7873953_184 Aerotolerance regulator N-terminal - - - 0.000000000000000000000003412 119.0
TLS3_k127_7873953_185 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000001558 104.0
TLS3_k127_7873953_186 Protein of unknown function (DUF4242) - - - 0.00000000000000000000001723 103.0
TLS3_k127_7873953_187 PHP-associated - - - 0.00000000000000000000001768 110.0
TLS3_k127_7873953_188 polygalacturonase activity - - - 0.00000000000000000000002635 114.0
TLS3_k127_7873953_189 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.00000000000000000000003809 107.0
TLS3_k127_7873953_19 COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 584.0
TLS3_k127_7873953_190 Maf-like protein K06287 - - 0.00000000000000000000003941 108.0
TLS3_k127_7873953_191 PFAM PEGA domain - - - 0.00000000000000000000004159 104.0
TLS3_k127_7873953_193 carbon utilization K02664 - - 0.0000000000000000000004443 104.0
TLS3_k127_7873953_194 Penicillinase repressor - - - 0.0000000000000000000004974 100.0
TLS3_k127_7873953_195 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase - - - 0.000000000000000000001165 98.0
TLS3_k127_7873953_196 Ribosomal protein L31 K02909 - - 0.000000000000000000003162 98.0
TLS3_k127_7873953_197 Histidine kinase - - - 0.000000000000000000005258 106.0
TLS3_k127_7873953_198 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000663 98.0
TLS3_k127_7873953_199 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000002542 100.0
TLS3_k127_7873953_2 response to heat K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 8.222e-303 952.0
TLS3_k127_7873953_20 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 565.0
TLS3_k127_7873953_200 Histidine kinase - - - 0.00000000000000000003571 106.0
TLS3_k127_7873953_202 Tfp pilus assembly protein FimV - - - 0.0000000000000000001815 100.0
TLS3_k127_7873953_203 Ankyrin repeats (many copies) - - - 0.0000000000000000002035 103.0
TLS3_k127_7873953_204 tail collar domain protein - - - 0.0000000000000000002495 103.0
TLS3_k127_7873953_205 hemolysin activation secretion protein - - - 0.0000000000000000003728 103.0
TLS3_k127_7873953_206 - - - - 0.00000000000000001526 93.0
TLS3_k127_7873953_207 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000000000002405 90.0
TLS3_k127_7873953_208 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000001258 84.0
TLS3_k127_7873953_209 GIY-YIG type nucleases (URI domain) K02342 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 0.0000000000000001904 92.0
TLS3_k127_7873953_21 PIN domain K07175 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 565.0
TLS3_k127_7873953_210 - - - - 0.0000000000000002119 82.0
TLS3_k127_7873953_211 - - - - 0.00000000000000026 92.0
TLS3_k127_7873953_212 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000005855 86.0
TLS3_k127_7873953_213 Aldehyde dehydrogenase K00128 - 1.2.1.3 0.000000000000002742 78.0
TLS3_k127_7873953_215 Large family of predicted nucleotide-binding domains K18828 - - 0.000000000000007626 78.0
TLS3_k127_7873953_216 Domain of unknown function (DUF4286) - - - 0.0000000000001139 76.0
TLS3_k127_7873953_217 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417,K03225 - - 0.0000000000002254 75.0
TLS3_k127_7873953_218 AsmA family - - - 0.0000000000002445 80.0
TLS3_k127_7873953_219 TM2 domain - - - 0.0000000000003489 76.0
TLS3_k127_7873953_22 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 557.0
TLS3_k127_7873953_220 sequence-specific DNA binding - - - 0.0000000000003522 74.0
TLS3_k127_7873953_221 Protein of unknown function (DUF3618) - - - 0.000000000001553 77.0
TLS3_k127_7873953_222 Protein of unknown function, DUF255 - - - 0.000000000007734 75.0
TLS3_k127_7873953_223 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.00000000001509 77.0
TLS3_k127_7873953_224 BON domain - - - 0.00000000002187 76.0
TLS3_k127_7873953_225 - - - - 0.00000000004409 75.0
TLS3_k127_7873953_226 Reprolysin (M12B) family zinc metalloprotease - - - 0.000000000112 74.0
TLS3_k127_7873953_227 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000001183 71.0
TLS3_k127_7873953_229 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.0000000009862 64.0
TLS3_k127_7873953_23 ATP dependent DNA ligase C terminal region K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 561.0
TLS3_k127_7873953_230 - - - - 0.000000001066 68.0
TLS3_k127_7873953_231 - - - - 0.000000001937 70.0
TLS3_k127_7873953_232 Dioxygenase K00449 - 1.13.11.3 0.000000007501 65.0
TLS3_k127_7873953_233 SNARE associated Golgi protein - - - 0.00000001106 64.0
TLS3_k127_7873953_234 PD-(D/E)XK nuclease superfamily - - - 0.00000001381 57.0
TLS3_k127_7873953_235 domain, Protein K11904,K12132 - 2.7.11.1 0.00000002414 62.0
TLS3_k127_7873953_236 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA - - - 0.00000005361 62.0
TLS3_k127_7873953_237 AAA domain - - - 0.00000007043 56.0
TLS3_k127_7873953_238 Peptidase propeptide and YPEB domain - - - 0.0000001149 64.0
TLS3_k127_7873953_239 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000003927 62.0
TLS3_k127_7873953_24 NAD- dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 522.0
TLS3_k127_7873953_240 Putative zinc-finger - - - 0.0000006553 61.0
TLS3_k127_7873953_241 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749 - - 0.0000007077 60.0
TLS3_k127_7873953_242 Lactonase, 7-bladed beta-propeller - - - 0.00000335 59.0
TLS3_k127_7873953_243 - - - - 0.000004995 55.0
TLS3_k127_7873953_245 STAS domain - - - 0.00001497 53.0
TLS3_k127_7873953_246 Glycosyltransferase Family 4 - - - 0.00007346 55.0
TLS3_k127_7873953_248 His Kinase A (phosphoacceptor) domain - - - 0.0001612 50.0
TLS3_k127_7873953_249 - - - - 0.0001975 48.0
TLS3_k127_7873953_25 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 514.0
TLS3_k127_7873953_250 - - - - 0.0002545 51.0
TLS3_k127_7873953_251 - - - - 0.0007299 50.0
TLS3_k127_7873953_26 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 511.0
TLS3_k127_7873953_27 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 499.0
TLS3_k127_7873953_28 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 485.0
TLS3_k127_7873953_29 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 462.0
TLS3_k127_7873953_3 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.457e-298 930.0
TLS3_k127_7873953_30 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 455.0
TLS3_k127_7873953_31 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 458.0
TLS3_k127_7873953_32 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 449.0
TLS3_k127_7873953_33 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K07823 - 2.3.1.174 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 442.0
TLS3_k127_7873953_34 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 426.0
TLS3_k127_7873953_35 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009464 424.0
TLS3_k127_7873953_36 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 425.0
TLS3_k127_7873953_37 Winged helix DNA-binding domain K09927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 419.0
TLS3_k127_7873953_38 ATPase associated with K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 405.0
TLS3_k127_7873953_39 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 405.0
TLS3_k127_7873953_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.565e-286 898.0
TLS3_k127_7873953_40 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007276 395.0
TLS3_k127_7873953_41 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 400.0
TLS3_k127_7873953_42 beta-lactamase activity K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 405.0
TLS3_k127_7873953_43 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 387.0
TLS3_k127_7873953_44 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 385.0
TLS3_k127_7873953_45 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 383.0
TLS3_k127_7873953_46 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 385.0
TLS3_k127_7873953_47 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 380.0
TLS3_k127_7873953_48 SMART Tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 392.0
TLS3_k127_7873953_49 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008816 380.0
TLS3_k127_7873953_5 DEAD DEAH box helicase K03724 - - 1.539e-279 885.0
TLS3_k127_7873953_50 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 379.0
TLS3_k127_7873953_51 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009484 372.0
TLS3_k127_7873953_52 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 369.0
TLS3_k127_7873953_53 tRNA synthetase class II K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 372.0
TLS3_k127_7873953_54 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 366.0
TLS3_k127_7873953_55 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 379.0
TLS3_k127_7873953_56 major pilin protein fima - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 368.0
TLS3_k127_7873953_57 With PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA K02609 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 361.0
TLS3_k127_7873953_58 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 365.0
TLS3_k127_7873953_59 Nucleotidyl transferase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 343.0
TLS3_k127_7873953_6 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 4.659e-260 813.0
TLS3_k127_7873953_60 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain K01840 - 5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 345.0
TLS3_k127_7873953_61 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 351.0
TLS3_k127_7873953_62 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 363.0
TLS3_k127_7873953_63 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 344.0
TLS3_k127_7873953_64 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 329.0
TLS3_k127_7873953_65 flagellar motor switch protein K02416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 325.0
TLS3_k127_7873953_66 ABC-type (unclassified) transport system ATPase K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 318.0
TLS3_k127_7873953_67 CorA-like Mg2+ transporter protein K16074 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 321.0
TLS3_k127_7873953_68 Metallopeptidase family M24 K01262 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 318.0
TLS3_k127_7873953_69 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 310.0
TLS3_k127_7873953_7 SNF2 Helicase protein - - - 1.764e-248 805.0
TLS3_k127_7873953_70 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 311.0
TLS3_k127_7873953_71 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 305.0
TLS3_k127_7873953_72 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 325.0
TLS3_k127_7873953_73 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 308.0
TLS3_k127_7873953_74 Nucleic acid binding K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 304.0
TLS3_k127_7873953_75 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 316.0
TLS3_k127_7873953_76 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 306.0
TLS3_k127_7873953_77 Iron/manganese superoxide dismutases, alpha-hairpin domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007607 294.0
TLS3_k127_7873953_78 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 285.0
TLS3_k127_7873953_79 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004856 289.0
TLS3_k127_7873953_8 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 1.595e-236 739.0
TLS3_k127_7873953_80 Integral membrane protein TerC family K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001083 296.0
TLS3_k127_7873953_81 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000001572 268.0
TLS3_k127_7873953_82 D-isomer specific 2-hydroxyacid dehydrogenase K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000004817 272.0
TLS3_k127_7873953_83 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001589 264.0
TLS3_k127_7873953_84 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003328 270.0
TLS3_k127_7873953_85 Periplasmic component of the Tol biopolymer transport K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000418 268.0
TLS3_k127_7873953_86 COG0147 Anthranilate para-aminobenzoate synthases component I K01665 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000006936 265.0
TLS3_k127_7873953_87 NnrU protein K21310 - 2.1.1.334 0.00000000000000000000000000000000000000000000000000000000000000000000000238 253.0
TLS3_k127_7873953_88 Transcriptional regulator K03655,K03724,K07013 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000013 246.0
TLS3_k127_7873953_89 Mitochondrial fission ELM1 K07276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000156 253.0
TLS3_k127_7873953_9 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 6.231e-228 721.0
TLS3_k127_7873953_90 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001362 249.0
TLS3_k127_7873953_91 von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003172 262.0
TLS3_k127_7873953_92 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000001994 243.0
TLS3_k127_7873953_93 mannose-6-phosphate isomerase K01809 - 5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000008016 246.0
TLS3_k127_7873953_94 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000004756 240.0
TLS3_k127_7873953_95 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000003217 231.0
TLS3_k127_7873953_96 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000051 233.0
TLS3_k127_7873953_97 cellular response to dsDNA K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000001109 228.0
TLS3_k127_7873953_99 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000793 222.0
TLS3_k127_7986928_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1172.0
TLS3_k127_7986928_1 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K01507,K15987 - 3.6.1.1 1.271e-285 901.0
TLS3_k127_7986928_10 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 321.0
TLS3_k127_7986928_11 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 329.0
TLS3_k127_7986928_12 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 309.0
TLS3_k127_7986928_13 PFAM NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 307.0
TLS3_k127_7986928_14 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001453 290.0
TLS3_k127_7986928_15 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008469 283.0
TLS3_k127_7986928_16 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008244 276.0
TLS3_k127_7986928_17 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001151 267.0
TLS3_k127_7986928_18 Glycosyl hydrolases family 35 K12308 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000001159 289.0
TLS3_k127_7986928_19 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000002751 249.0
TLS3_k127_7986928_2 Rhodanese Homology Domain K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 542.0
TLS3_k127_7986928_20 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000005333 241.0
TLS3_k127_7986928_21 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000001027 238.0
TLS3_k127_7986928_22 O-acyltransferase activity K00661,K03818 - 2.3.1.79 0.0000000000000000000000000000000000000000000000000000000000006325 216.0
TLS3_k127_7986928_23 MafB19-like deaminase K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000001536 213.0
TLS3_k127_7986928_24 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000000000005316 190.0
TLS3_k127_7986928_25 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000008625 176.0
TLS3_k127_7986928_26 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000000000000003658 167.0
TLS3_k127_7986928_27 Collagen triple helix repeat - - - 0.00000000000000000000000000000000000001442 167.0
TLS3_k127_7986928_28 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.0000000000000000000000000000000000105 156.0
TLS3_k127_7986928_29 Domain of unknown function (DUF368) K08974 - - 0.0000000000000000000000000000000004238 144.0
TLS3_k127_7986928_3 TrkA-C domain K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 539.0
TLS3_k127_7986928_30 Transglutaminase-like superfamily - - - 0.0000000000000000000000000107 121.0
TLS3_k127_7986928_31 COG0845 Membrane-fusion protein - - - 0.00000000000000000000000006788 124.0
TLS3_k127_7986928_32 nuclear chromosome segregation - - - 0.00000000000001923 87.0
TLS3_k127_7986928_33 Transcriptional Regulator ArsR Family - - - 0.00000000000131 71.0
TLS3_k127_7986928_34 Staphylococcal nuclease homologues - - - 0.000000000002862 76.0
TLS3_k127_7986928_35 Universal bacterial protein YeaZ K14742 - - 0.00000000001416 74.0
TLS3_k127_7986928_36 - - - - 0.000000002566 59.0
TLS3_k127_7986928_37 spermatid development - GO:0000003,GO:0003006,GO:0005575,GO:0005623,GO:0005929,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0008150,GO:0009987,GO:0019953,GO:0022412,GO:0022414,GO:0030154,GO:0031514,GO:0032501,GO:0032502,GO:0032504,GO:0036126,GO:0042995,GO:0043226,GO:0044464,GO:0044703,GO:0048232,GO:0048468,GO:0048515,GO:0048609,GO:0048856,GO:0048869,GO:0051704,GO:0097223,GO:0097729,GO:0120025 - 0.00000004533 55.0
TLS3_k127_7986928_38 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000001052 64.0
TLS3_k127_7986928_39 helix_turn_helix, Lux Regulon - - - 0.0000001064 58.0
TLS3_k127_7986928_4 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 523.0
TLS3_k127_7986928_5 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 428.0
TLS3_k127_7986928_6 ADP-glyceromanno-heptose 6-epimerase activity K19997 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016020,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.1.3.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 424.0
TLS3_k127_7986928_7 UDP-arabinose 4-epimerase K12448 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005975,GO:0005996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009790,GO:0009791,GO:0009793,GO:0009832,GO:0009856,GO:0009987,GO:0010154,GO:0012505,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019322,GO:0019566,GO:0019567,GO:0022414,GO:0032501,GO:0032502,GO:0042546,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044706,GO:0046364,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0048868,GO:0050373,GO:0051704,GO:0061458,GO:0071554,GO:0071669,GO:0071704,GO:0071840,GO:1901576 5.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 360.0
TLS3_k127_7986928_8 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 336.0
TLS3_k127_7986928_9 PFAM Stage II sporulation protein E (SpoIIE) K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 325.0
TLS3_k127_8328857_0 Outer membrane protein assembly complex, YaeT protein K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 597.0
TLS3_k127_8328857_1 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 546.0
TLS3_k127_8328857_10 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000001794 277.0
TLS3_k127_8328857_11 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000002183 211.0
TLS3_k127_8328857_12 TspO/MBR family K05770 - - 0.000000000000000000000000000000000000000000005088 168.0
TLS3_k127_8328857_13 - - - - 0.0000000000000000000000000000000001669 134.0
TLS3_k127_8328857_14 Helix-turn-helix domain, rpiR family - - - 0.0000000000000000000000003877 116.0
TLS3_k127_8328857_15 - - - - 0.0000000000000000001575 92.0
TLS3_k127_8328857_16 DNA-templated transcription, initiation K03088 - - 0.00000000000008405 79.0
TLS3_k127_8328857_18 sequence-specific DNA binding K07467 - - 0.0002323 49.0
TLS3_k127_8328857_19 Phage derived protein Gp49-like (DUF891) - - - 0.000302 48.0
TLS3_k127_8328857_2 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 524.0
TLS3_k127_8328857_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005839 414.0
TLS3_k127_8328857_4 phage plasmid primase K06919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 391.0
TLS3_k127_8328857_5 PFAM CBS domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 374.0
TLS3_k127_8328857_6 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 362.0
TLS3_k127_8328857_7 Coenzyme A transferase K01027,K01028,K01031 - 2.8.3.5,2.8.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 340.0
TLS3_k127_8328857_8 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 339.0
TLS3_k127_8328857_9 ParB-like nuclease domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 302.0
TLS3_k127_986312_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 4.027e-198 630.0
TLS3_k127_986312_1 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 1.055e-194 629.0
TLS3_k127_986312_10 AbgT putative transporter family K12942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 439.0
TLS3_k127_986312_11 ATPase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 391.0
TLS3_k127_986312_12 membrane K07148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 368.0
TLS3_k127_986312_13 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 363.0
TLS3_k127_986312_14 synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0008825,GO:0009058,GO:0009059,GO:0009273,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016853,GO:0016859,GO:0017144,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0032259,GO:0032787,GO:0034645,GO:0035821,GO:0042546,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0044003,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044464,GO:0046394,GO:0046500,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051817,GO:0051832,GO:0051834,GO:0052031,GO:0052167,GO:0052173,GO:0052200,GO:0052255,GO:0052306,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0075136,GO:1901576 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 347.0
TLS3_k127_986312_15 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 321.0
TLS3_k127_986312_16 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008974 314.0
TLS3_k127_986312_17 Arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 308.0
TLS3_k127_986312_18 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 319.0
TLS3_k127_986312_19 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 291.0
TLS3_k127_986312_2 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 521.0
TLS3_k127_986312_20 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 284.0
TLS3_k127_986312_21 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001677 283.0
TLS3_k127_986312_22 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001242 261.0
TLS3_k127_986312_23 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001803 244.0
TLS3_k127_986312_24 response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000001402 237.0
TLS3_k127_986312_25 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000001372 226.0
TLS3_k127_986312_26 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000001113 210.0
TLS3_k127_986312_27 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000222 189.0
TLS3_k127_986312_28 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000007649 190.0
TLS3_k127_986312_29 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.0000000000000000000000000000000000000000000001311 184.0
TLS3_k127_986312_3 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 516.0
TLS3_k127_986312_30 asparaginase activity K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000001405 171.0
TLS3_k127_986312_31 Domain of unknown function (DUF892) - - - 0.000000000000000000000000000000000000000000007259 175.0
TLS3_k127_986312_32 - - - - 0.0000000000000000000000000000000000000000000209 169.0
TLS3_k127_986312_33 Acetyltransferase (GNAT) domain K03817 - - 0.00000000000000000000000000000000000000000006576 170.0
TLS3_k127_986312_34 Histidine kinase - - - 0.00000000000000000000000000000000000000001269 175.0
TLS3_k127_986312_35 chain release factor - - - 0.0000000000000000000000000000000000000001039 157.0
TLS3_k127_986312_36 - - - - 0.000000000000000000000000000000000000001954 159.0
TLS3_k127_986312_37 Protein of unknown function (DUF1579) - - - 0.0000000000000000000000000000000002171 140.0
TLS3_k127_986312_38 - - - - 0.000000000000000000000000000000004319 136.0
TLS3_k127_986312_39 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000001902 137.0
TLS3_k127_986312_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 474.0
TLS3_k127_986312_40 - - - - 0.0000000000000000000000000003564 119.0
TLS3_k127_986312_42 GGDEF domain - - - 0.0000000000000002474 94.0
TLS3_k127_986312_43 Phosphoglycerate mutase family - - - 0.00000000000002986 83.0
TLS3_k127_986312_44 Mo-molybdopterin cofactor metabolic process K03636,K21142 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.12 0.00000000004904 66.0
TLS3_k127_986312_46 Bacterial PH domain - - - 0.0000003719 60.0
TLS3_k127_986312_48 Prokaryotic N-terminal methylation motif - - - 0.0002112 52.0
TLS3_k127_986312_5 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 463.0
TLS3_k127_986312_50 dextransucrase activity - - - 0.000248 52.0
TLS3_k127_986312_51 HNH endonuclease - - - 0.0004454 49.0
TLS3_k127_986312_6 Thermophilic metalloprotease (M29) K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 458.0
TLS3_k127_986312_7 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 460.0
TLS3_k127_986312_8 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007511 463.0
TLS3_k127_986312_9 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 458.0