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Overview

ID MAG04062
Name TLS3_bin.51
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota_B
Class Binatia
Order UBA9968
Family UBA9968
Genus WHTF01
Species
Assembly information
Completeness (%) 82.2
Contamination (%) 3.61
GC content (%) 55.0
N50 (bp) 15,819
Genome size (bp) 2,821,025

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2637

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1006824_0 Aldehyde dehydrogenase family K00128,K00135,K22187 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 8.674e-219 689.0
TLS3_k127_1006824_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 526.0
TLS3_k127_1006824_2 Tripartite tricarboxylate transporter TctA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 496.0
TLS3_k127_1006824_3 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 314.0
TLS3_k127_1006824_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009914 304.0
TLS3_k127_1006824_5 PAC2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000001415 232.0
TLS3_k127_1006824_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000006113 200.0
TLS3_k127_1006824_7 photosynthesis - - - 0.000000000000000000000000000000000000000000001049 171.0
TLS3_k127_1006824_8 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.00000000000000000000000000000000000000000003284 164.0
TLS3_k127_1021242_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 9.048e-194 615.0
TLS3_k127_1021242_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002527 283.0
TLS3_k127_1021242_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000005889 239.0
TLS3_k127_1021242_3 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000002909 169.0
TLS3_k127_1021242_4 peptidyl-tyrosine sulfation - - - 0.00000000000000001088 88.0
TLS3_k127_1021242_5 PFAM Tetratricopeptide repeat - - - 0.0001107 52.0
TLS3_k127_1021242_6 peptidyl-tyrosine sulfation - - - 0.0004641 51.0
TLS3_k127_102508_0 Kelch repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000021 247.0
TLS3_k127_102508_1 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000347 211.0
TLS3_k127_102508_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.000002467 50.0
TLS3_k127_102508_3 molybdopterin cofactor binding K00183 - - 0.0003338 46.0
TLS3_k127_1063606_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000001922 193.0
TLS3_k127_1063606_1 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000673 198.0
TLS3_k127_1063606_2 Binding-protein-dependent transport system inner membrane component K02050,K15552 - - 0.0000000000000000000000000000000000000000000000001095 185.0
TLS3_k127_1063606_3 Male sterility protein K01784 - 5.1.3.2 0.0000000000000000000000000000000007714 143.0
TLS3_k127_1063606_4 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 GO:0003674,GO:0005215 - 0.0000000000009715 79.0
TLS3_k127_1095305_0 Cytochrome c - - - 1.483e-308 961.0
TLS3_k127_1095305_1 Fe-S oxidoreductase - - - 2.013e-305 947.0
TLS3_k127_1095305_2 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 2.863e-211 666.0
TLS3_k127_1095305_3 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 518.0
TLS3_k127_1095305_4 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 442.0
TLS3_k127_1095305_5 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000167 128.0
TLS3_k127_1095305_6 regulatory protein IclR - - - 0.00000000000136 70.0
TLS3_k127_1095305_7 Heavy metal transport detoxification protein K17686 - 3.6.3.54 0.0001479 46.0
TLS3_k127_1113738_0 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 356.0
TLS3_k127_1113738_1 Fic/DOC family - - - 0.0000000000000000000000000000000000009142 140.0
TLS3_k127_1113738_2 membrane-bound metal-dependent K07038 - - 0.0000000000000000000000118 105.0
TLS3_k127_1113963_0 TIGRFAM phosphate binding protein K02040 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 491.0
TLS3_k127_1113963_1 PFAM Binding-protein-dependent transport system inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 447.0
TLS3_k127_1113963_10 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003939 255.0
TLS3_k127_1113963_11 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000000000000000000000000000000000000000000000002539 246.0
TLS3_k127_1113963_12 Bacterial protein of unknown function (DUF839) K07093 - - 0.000000000000000000000000000000000000000000000000000000000000003447 226.0
TLS3_k127_1113963_13 MafB19-like deaminase K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 0.000000000000000000000000000000000000000000000000006641 187.0
TLS3_k127_1113963_14 low molecular weight K03741 - 1.20.4.1 0.00000000000000000000000000000000002018 154.0
TLS3_k127_1113963_15 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000002532 144.0
TLS3_k127_1113963_16 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000001798 126.0
TLS3_k127_1113963_17 Bacterial protein of unknown function (DUF839) K07093 - - 0.000000000000000000000000002759 112.0
TLS3_k127_1113963_18 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000005272 110.0
TLS3_k127_1113963_19 - - - - 0.000000000000000000007111 101.0
TLS3_k127_1113963_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 443.0
TLS3_k127_1113963_20 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000000000001197 74.0
TLS3_k127_1113963_21 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000003615 70.0
TLS3_k127_1113963_22 Universal stress protein - - - 0.000000000004147 73.0
TLS3_k127_1113963_23 PFAM CHAD domain containing protein - - - 0.00000004062 64.0
TLS3_k127_1113963_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 429.0
TLS3_k127_1113963_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 378.0
TLS3_k127_1113963_5 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 317.0
TLS3_k127_1113963_6 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 315.0
TLS3_k127_1113963_7 metal-dependent phosphohydrolase, HD sub domain K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004541 292.0
TLS3_k127_1113963_8 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002744 274.0
TLS3_k127_1113963_9 dTDP biosynthetic process K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.9,4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003295 273.0
TLS3_k127_1159490_0 DNA topoisomerase II activity K03167 - 5.99.1.3 6.628e-301 935.0
TLS3_k127_1159490_1 Belongs to the aldehyde dehydrogenase family K13821 - 1.2.1.88,1.5.5.2 3.113e-299 948.0
TLS3_k127_1159490_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 335.0
TLS3_k127_1159490_11 PFAM ABC transporter related K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 322.0
TLS3_k127_1159490_12 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 302.0
TLS3_k127_1159490_13 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 295.0
TLS3_k127_1159490_14 Cytidylyltransferase K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000175 274.0
TLS3_k127_1159490_15 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000207 196.0
TLS3_k127_1159490_16 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000002083 190.0
TLS3_k127_1159490_17 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000664 159.0
TLS3_k127_1159490_18 PTS HPr component phosphorylation site K11189 - - 0.0000000000000000000006427 98.0
TLS3_k127_1159490_19 - - - - 0.000000000000000000001058 95.0
TLS3_k127_1159490_2 CTP synthase N-terminus K01937 - 6.3.4.2 1.499e-250 782.0
TLS3_k127_1159490_20 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000009591 96.0
TLS3_k127_1159490_21 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000001667 78.0
TLS3_k127_1159490_22 Hydantoin racemase K16841 - 5.1.99.3 0.000000005078 66.0
TLS3_k127_1159490_23 Nitrile hydratase beta subunit - - - 0.00000001863 59.0
TLS3_k127_1159490_25 - - - - 0.000009908 55.0
TLS3_k127_1159490_26 lipopolysaccharide transmembrane transporter activity K09774,K11719 - - 0.00001332 55.0
TLS3_k127_1159490_27 NMT1-like family K02051 - - 0.0001078 54.0
TLS3_k127_1159490_28 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0002958 51.0
TLS3_k127_1159490_3 Asparaginase - - - 8.053e-198 631.0
TLS3_k127_1159490_4 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 607.0
TLS3_k127_1159490_5 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 548.0
TLS3_k127_1159490_6 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 470.0
TLS3_k127_1159490_7 SIS domain K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 400.0
TLS3_k127_1159490_8 PFAM alpha beta hydrolase K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 389.0
TLS3_k127_1159490_9 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 354.0
TLS3_k127_1178143_0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 1.087e-273 859.0
TLS3_k127_1178143_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 469.0
TLS3_k127_1178143_2 Putative integral membrane protein (DUF2391) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009151 262.0
TLS3_k127_1178143_3 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000006668 226.0
TLS3_k127_1178143_4 GAF domain - - - 0.00000000000000000000000000000000000000000000147 183.0
TLS3_k127_1178143_5 Response regulator receiver - - - 0.000000000000000000000000000005322 124.0
TLS3_k127_1178143_6 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000009445 119.0
TLS3_k127_1178143_7 lactoylglutathione lyase activity - - - 0.000001469 53.0
TLS3_k127_1178143_8 Transcriptional regulatory protein, C terminal - - - 0.0001341 45.0
TLS3_k127_1206926_0 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000004977 194.0
TLS3_k127_1206926_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000173 110.0
TLS3_k127_1206926_2 Helix-turn-helix domain - - - 0.00000000000007695 79.0
TLS3_k127_1206926_4 Transposase K07491 - - 0.00002068 48.0
TLS3_k127_1216503_0 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.0000000000000000000000000000002899 132.0
TLS3_k127_1216503_1 nuclease activity - - - 0.000000000000000000000005637 104.0
TLS3_k127_1216503_2 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000009098 104.0
TLS3_k127_1216503_3 nuclease activity - - - 0.00000000000001382 75.0
TLS3_k127_1216503_4 positive regulation of growth - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.000000003417 59.0
TLS3_k127_1246182_0 mechanosensitive ion channel activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006246 588.0
TLS3_k127_1246182_1 ornithine cyclodeaminase K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 333.0
TLS3_k127_1246182_10 Hsp90 protein K04079 - - 0.0002737 51.0
TLS3_k127_1246182_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000002204 228.0
TLS3_k127_1246182_3 PFAM amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000004745 186.0
TLS3_k127_1246182_4 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000002189 165.0
TLS3_k127_1246182_5 transporter component K07112 - - 0.0000000000000000000000000000000000000008693 152.0
TLS3_k127_1246182_6 - K07112 - - 0.0000000000000000000000000000000000001483 148.0
TLS3_k127_1246182_7 Universal stress protein - - - 0.000000000000000002344 91.0
TLS3_k127_1246182_8 TPR Domain containing protein. Source PGD - - - 0.000001973 53.0
TLS3_k127_1246182_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000691 53.0
TLS3_k127_1254678_0 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 373.0
TLS3_k127_1254678_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000235 267.0
TLS3_k127_1254678_2 CHASE3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003674 238.0
TLS3_k127_1254678_3 Rhodanese-like domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000008245 235.0
TLS3_k127_1254678_4 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000000000000008934 152.0
TLS3_k127_1254678_5 PFAM Cyclic nucleotide-binding K10914 - - 0.0000000000000002405 88.0
TLS3_k127_1254678_6 TIGRFAM ABC transporter, substrate-binding protein, aliphatic K02051 - - 0.000000000006116 76.0
TLS3_k127_1254678_7 Transcriptional regulator - - - 0.00000002337 61.0
TLS3_k127_1254678_8 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000003373 51.0
TLS3_k127_1254678_9 Glutathione S-transferase, C-terminal domain K00799 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0043603,GO:0044237,GO:0044424,GO:0044464,GO:0051186,GO:0071704,GO:1901564 2.5.1.18 0.0006651 43.0
TLS3_k127_1309256_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 562.0
TLS3_k127_1309256_1 Aldehyde dehydrogenase family K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 472.0
TLS3_k127_1309256_2 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000005765 212.0
TLS3_k127_1309256_3 Dehydratase K14449,K18290 - 4.2.1.148,4.2.1.56 0.000000000000000000000000000000000000000003659 156.0
TLS3_k127_1309256_4 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000341 160.0
TLS3_k127_1309256_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000006363 104.0
TLS3_k127_1309256_6 Major Facilitator Superfamily - - - 0.0000000006595 71.0
TLS3_k127_1313677_0 acetyl-coa acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008125 303.0
TLS3_k127_1313677_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000008786 228.0
TLS3_k127_1313677_2 3-hydroxyacyl-CoA dehydrogenase K00074,K15016,K15019 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0043956 1.1.1.157,1.1.1.35,4.2.1.116,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000001087 221.0
TLS3_k127_1313677_3 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000001245 178.0
TLS3_k127_1313677_4 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000268 169.0
TLS3_k127_1313677_5 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000003441 153.0
TLS3_k127_1313677_6 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000004556 127.0
TLS3_k127_1313677_7 IMP dehydrogenase activity - - - 0.000000000000000000000000000002555 124.0
TLS3_k127_131794_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.218e-286 904.0
TLS3_k127_131794_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.905e-255 796.0
TLS3_k127_131794_10 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000001089 243.0
TLS3_k127_131794_11 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000002016 177.0
TLS3_k127_131794_12 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000001151 174.0
TLS3_k127_131794_13 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000001549 158.0
TLS3_k127_131794_14 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000001775 134.0
TLS3_k127_131794_15 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000003256 126.0
TLS3_k127_131794_16 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000001127 106.0
TLS3_k127_131794_17 permease - - - 0.0000000000000000000002531 113.0
TLS3_k127_131794_18 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000005329 96.0
TLS3_k127_131794_19 von Willebrand factor type A - - - 0.0000000000000003413 93.0
TLS3_k127_131794_2 AI-2E family transporter - - - 6.558e-225 722.0
TLS3_k127_131794_20 cytochrome c K00406 - - 0.000000000000004097 80.0
TLS3_k127_131794_21 COG0607 Rhodanese-related sulfurtransferase - - - 0.000000009729 57.0
TLS3_k127_131794_22 PFAM Rhodanese-like domain - - - 0.000001171 54.0
TLS3_k127_131794_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 520.0
TLS3_k127_131794_4 AAA domain K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 432.0
TLS3_k127_131794_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 304.0
TLS3_k127_131794_6 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 312.0
TLS3_k127_131794_7 Putative glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001662 290.0
TLS3_k127_131794_8 quinone binding K12057,K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000001689 270.0
TLS3_k127_131794_9 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001561 238.0
TLS3_k127_1344181_0 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 345.0
TLS3_k127_1344181_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000001315 190.0
TLS3_k127_1344181_2 with the TIM-barrel fold - - - 0.00000000000000000000000000000001078 139.0
TLS3_k127_1344181_3 Forkhead associated domain - - - 0.000000000000000000000000001805 124.0
TLS3_k127_1344181_4 CoA-transferase family III K18702 - 2.8.3.19 0.00003149 46.0
TLS3_k127_1368559_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 347.0
TLS3_k127_1371955_0 NMT1/THI5 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 372.0
TLS3_k127_1371955_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000003502 245.0
TLS3_k127_1371955_2 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.000000000000000000000000000000000007378 141.0
TLS3_k127_1399479_0 Male sterility protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000005458 225.0
TLS3_k127_1399479_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000001161 197.0
TLS3_k127_1444990_0 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 516.0
TLS3_k127_1444990_1 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 331.0
TLS3_k127_1444990_2 COG0665 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000000000000000000004387 242.0
TLS3_k127_1444990_3 FIST C domain - GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000001849 162.0
TLS3_k127_1444990_4 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000006565 141.0
TLS3_k127_1444990_5 Ketopantoate reductase PanE/ApbA K00077 - 1.1.1.169 0.0000000000000000000000000000633 121.0
TLS3_k127_1444990_6 - - - - 0.00000000000000000000009624 105.0
TLS3_k127_1444990_7 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000001795 102.0
TLS3_k127_1444990_8 Belongs to the universal stress protein A family - - - 0.000000000000000000005433 98.0
TLS3_k127_1463435_0 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001109 261.0
TLS3_k127_1463435_1 tryptophan 2,3-dioxygenase activity K00453,K03392 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11,4.1.1.45 0.00000000000000000000000000008206 117.0
TLS3_k127_1463435_2 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.000000000000000000000002262 103.0
TLS3_k127_1511063_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 447.0
TLS3_k127_1511063_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 394.0
TLS3_k127_1511063_2 [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000000000001136 194.0
TLS3_k127_152667_0 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 429.0
TLS3_k127_152667_1 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 415.0
TLS3_k127_152667_2 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000002703 156.0
TLS3_k127_152667_3 - - - - 0.00000000000000000000002095 104.0
TLS3_k127_152667_4 Cytochrome c - - - 0.000000000000000000001828 100.0
TLS3_k127_152667_5 Glutathione transferase K21253,K21264,K21265 - 2.5.1.18 0.00000000000009793 76.0
TLS3_k127_152667_6 YCII-related domain - - - 0.000009884 51.0
TLS3_k127_1536825_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 328.0
TLS3_k127_1536825_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000007283 113.0
TLS3_k127_1536825_2 arylformamidase activity - - - 0.00000000000000006219 91.0
TLS3_k127_1536825_3 arylformamidase activity - - - 0.0000000000000009668 88.0
TLS3_k127_1536825_4 Bacterial extracellular solute-binding protein K02012 - - 0.0000000007641 70.0
TLS3_k127_1549175_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 558.0
TLS3_k127_1549175_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000001675 229.0
TLS3_k127_1549175_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000001118 119.0
TLS3_k127_1549175_3 Septum formation initiator K05589 - - 0.0001367 48.0
TLS3_k127_1574166_0 Ring hydroxylating alpha subunit (catalytic domain) K05549,K10619 - 1.14.12.10,1.14.12.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 413.0
TLS3_k127_1574166_1 Metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 360.0
TLS3_k127_1574166_2 Ring hydroxylating beta subunit K14749 - - 0.000000000000000000000000000000000000000000001846 170.0
TLS3_k127_1574166_3 Transposase K07491 - - 0.000001903 55.0
TLS3_k127_1609087_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000005439 225.0
TLS3_k127_1609087_1 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 0.000000000000000000000000000000000000000000000000000000001184 207.0
TLS3_k127_1609087_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.00000000000000000000000000000000000000000001572 173.0
TLS3_k127_1609087_3 Phenylacetate-CoA oxygenase K02609 - 1.14.13.149 0.0000000000000000000000000000000000000003352 158.0
TLS3_k127_1609087_4 - - - - 0.000000000000000000000000000003194 123.0
TLS3_k127_1609087_5 Beta-lactamase superfamily domain - - - 0.0000005471 52.0
TLS3_k127_1754014_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 3.63e-209 658.0
TLS3_k127_1754014_1 PFAM ABC transporter K10008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 353.0
TLS3_k127_1754014_10 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000005879 157.0
TLS3_k127_1754014_11 Histidine phosphatase superfamily (branch 1) K03574,K08296 - 3.6.1.55 0.000000000000000000000000000000000228 138.0
TLS3_k127_1754014_12 NMT1-like family - - - 0.000000001515 67.0
TLS3_k127_1754014_2 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 347.0
TLS3_k127_1754014_3 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 344.0
TLS3_k127_1754014_4 Lytic transglycosylase catalytic K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005926 263.0
TLS3_k127_1754014_5 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000004689 241.0
TLS3_k127_1754014_6 PFAM binding-protein-dependent transport systems inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000008029 219.0
TLS3_k127_1754014_7 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.000000000000000000000000000000000000000000000000000000000001082 220.0
TLS3_k127_1754014_8 amino acid ABC transporter K02029 - - 0.000000000000000000000000000000000000000000000000002993 191.0
TLS3_k127_1754014_9 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000005887 174.0
TLS3_k127_1757594_0 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 475.0
TLS3_k127_1757594_1 Lipocalin-like domain - - - 0.00000000000000000000001333 105.0
TLS3_k127_1757594_2 - - - - 0.00000007512 55.0
TLS3_k127_1768366_0 mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth K15738 - - 2.53e-217 693.0
TLS3_k127_1768366_1 Glutathione S-transferase K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 388.0
TLS3_k127_1768366_10 Dehydratase K14449,K18290 - 4.2.1.148,4.2.1.56 0.000000000000000000000000000000000000000000000000000000000002415 213.0
TLS3_k127_1768366_11 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000172 198.0
TLS3_k127_1768366_12 COG0655 Multimeric flavodoxin WrbA - - - 0.00000000000000000000000000000000000000000000000002034 183.0
TLS3_k127_1768366_13 maF-like protein K03215,K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0030312,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0071944 2.1.1.190 0.00000000000000000000000000000000000000000000000007567 184.0
TLS3_k127_1768366_14 TIGRFAM carbohydrate kinase, thermoresistant glucokinase family K00851 - 2.7.1.12 0.0000000000000000000000000000000000000000000001215 175.0
TLS3_k127_1768366_15 YHS domain K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000449 170.0
TLS3_k127_1768366_16 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000002989 164.0
TLS3_k127_1768366_17 Phenylacetic acid - - - 0.000000000000000000000000000000000000001998 156.0
TLS3_k127_1768366_18 Belongs to the enoyl-CoA hydratase isomerase family K07546 - - 0.000000000000000000000000000000002695 140.0
TLS3_k127_1768366_19 HAD-hyrolase-like - - - 0.00000000000000000000000000000001454 135.0
TLS3_k127_1768366_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05541 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 381.0
TLS3_k127_1768366_20 Evidence 4 Homologs of previously reported genes of K07145,K21481 - 1.14.99.48,1.14.99.57 0.0000000000000000000000000000004637 125.0
TLS3_k127_1768366_21 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000003262 135.0
TLS3_k127_1768366_22 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000003137 121.0
TLS3_k127_1768366_23 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000007357 106.0
TLS3_k127_1768366_24 PFAM Amidohydrolase 2 - - - 0.00000000000000002355 94.0
TLS3_k127_1768366_25 metal-dependent hydrolase of the TIM-barrel fold - - - 0.0000000000000005548 90.0
TLS3_k127_1768366_27 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000001891 81.0
TLS3_k127_1768366_29 NfeD-like C-terminal, partner-binding - - - 0.00000000005157 68.0
TLS3_k127_1768366_3 Bile acid-inducible L-carnitine dehydratase protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 372.0
TLS3_k127_1768366_30 - - - - 0.00000002527 58.0
TLS3_k127_1768366_31 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000009611 60.0
TLS3_k127_1768366_32 Subtilase family - - - 0.0000005474 60.0
TLS3_k127_1768366_33 Evidence 5 No homology to any previously reported sequences - - - 0.000008595 55.0
TLS3_k127_1768366_34 Putative peptidoglycan binding domain - - - 0.00002189 53.0
TLS3_k127_1768366_4 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002453 287.0
TLS3_k127_1768366_5 Ornithine cyclodeaminase/mu-crystallin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001725 282.0
TLS3_k127_1768366_6 Lytic transglycosylase catalytic K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001204 269.0
TLS3_k127_1768366_7 PFAM CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001778 259.0
TLS3_k127_1768366_8 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000006997 234.0
TLS3_k127_1768366_9 Domain of unknown function (DUF1932) - - - 0.000000000000000000000000000000000000000000000000000000000001348 221.0
TLS3_k127_1781876_0 Domain of unknown function (DUF3552) K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 604.0
TLS3_k127_1781876_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 493.0
TLS3_k127_1781876_2 TIGRFAM metallophosphoesterase, MG_246 BB_0505 family K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 306.0
TLS3_k127_1781876_3 nickel-responsive regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000002137 149.0
TLS3_k127_1781876_4 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000003938 124.0
TLS3_k127_1781876_5 - - - - 0.00000000000000000008491 89.0
TLS3_k127_1781876_6 - - - - 0.000000000000009124 75.0
TLS3_k127_1781876_7 Cytochrome c K12263 - - 0.000000001499 64.0
TLS3_k127_1781876_8 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000005697 61.0
TLS3_k127_1797421_0 - - - - 0.00000000000000000000000000000000000000000000000002347 184.0
TLS3_k127_1797421_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000002342 179.0
TLS3_k127_1797421_2 - - - - 0.00000000000000000000000000007505 119.0
TLS3_k127_1797421_3 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000001509 80.0
TLS3_k127_1797421_4 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000009225 57.0
TLS3_k127_1877090_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 2.182e-315 986.0
TLS3_k127_1877090_1 TRCF K03723 - - 6.803e-315 1002.0
TLS3_k127_1877090_10 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 367.0
TLS3_k127_1877090_11 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 334.0
TLS3_k127_1877090_12 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007739 290.0
TLS3_k127_1877090_13 Mammalian cell entry related domain protein K02067,K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003593 273.0
TLS3_k127_1877090_14 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000615 243.0
TLS3_k127_1877090_15 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000004838 224.0
TLS3_k127_1877090_16 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000471 209.0
TLS3_k127_1877090_17 Protein conserved in bacteria K18480 - - 0.00000000000000000000000000000000000000001416 162.0
TLS3_k127_1877090_18 PpiC-type peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.00000000000000000000000000000000000004777 159.0
TLS3_k127_1877090_19 Iron-sulphur cluster biosynthesis - - - 0.0000000000000000000000000000006359 125.0
TLS3_k127_1877090_2 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 3.427e-282 872.0
TLS3_k127_1877090_20 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.000000000000000000000000000001388 127.0
TLS3_k127_1877090_21 Transcriptional regulator - - - 0.00000000000000000000000000001503 124.0
TLS3_k127_1877090_22 PFAM Transposase, IS4-like - - - 0.00000000000000000000000000007992 119.0
TLS3_k127_1877090_23 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K09459 - 4.1.1.82 0.000000000000000000000000009095 117.0
TLS3_k127_1877090_24 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000678 113.0
TLS3_k127_1877090_25 Unextendable partial coding region - - - 0.000000000002844 67.0
TLS3_k127_1877090_26 Domain of unknown function (DUF309) K09763 - - 0.0000000007258 65.0
TLS3_k127_1877090_27 - - - - 0.0000008115 52.0
TLS3_k127_1877090_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 5.925e-222 713.0
TLS3_k127_1877090_4 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007601 539.0
TLS3_k127_1877090_5 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 526.0
TLS3_k127_1877090_6 PFAM Transposase, IS4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 503.0
TLS3_k127_1877090_7 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 484.0
TLS3_k127_1877090_8 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 435.0
TLS3_k127_1877090_9 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 405.0
TLS3_k127_1890331_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 3.819e-212 689.0
TLS3_k127_1890331_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 3.943e-212 676.0
TLS3_k127_1890331_10 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001968 283.0
TLS3_k127_1890331_11 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000005587 242.0
TLS3_k127_1890331_12 PFAM cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000001034 188.0
TLS3_k127_1890331_13 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000005338 163.0
TLS3_k127_1890331_14 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000008471 134.0
TLS3_k127_1890331_15 LeuA allosteric (dimerisation) domain K01649 - 2.3.3.13 0.000000000000000000000000005133 116.0
TLS3_k127_1890331_16 - - - - 0.0000000000000001633 87.0
TLS3_k127_1890331_17 Monocopper oxidase-like protein K19791 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005911,GO:0008150,GO:0008152,GO:0009506,GO:0016020,GO:0016491,GO:0016722,GO:0030054,GO:0031224,GO:0031225,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0046658,GO:0055044,GO:0055114,GO:0071944 - 0.0004857 43.0
TLS3_k127_1890331_18 SCP-2 sterol transfer family - - - 0.0009359 48.0
TLS3_k127_1890331_2 oligoendopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 552.0
TLS3_k127_1890331_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 458.0
TLS3_k127_1890331_4 NMT1/THI5 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 398.0
TLS3_k127_1890331_5 ATPase associated with K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 370.0
TLS3_k127_1890331_6 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 340.0
TLS3_k127_1890331_7 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 329.0
TLS3_k127_1890331_8 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 314.0
TLS3_k127_1890331_9 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 289.0
TLS3_k127_1894488_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.63e-317 990.0
TLS3_k127_1894488_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.008e-253 788.0
TLS3_k127_1894488_10 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 496.0
TLS3_k127_1894488_11 DnaJ central domain K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 464.0
TLS3_k127_1894488_12 4,5-dihydroxyphthalate decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 447.0
TLS3_k127_1894488_13 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 362.0
TLS3_k127_1894488_14 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 359.0
TLS3_k127_1894488_15 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 320.0
TLS3_k127_1894488_16 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 309.0
TLS3_k127_1894488_17 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 294.0
TLS3_k127_1894488_18 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001923 283.0
TLS3_k127_1894488_19 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000007832 244.0
TLS3_k127_1894488_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.638e-239 749.0
TLS3_k127_1894488_20 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000003146 239.0
TLS3_k127_1894488_21 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000249 236.0
TLS3_k127_1894488_22 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000007339 222.0
TLS3_k127_1894488_23 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000002384 216.0
TLS3_k127_1894488_24 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000003575 212.0
TLS3_k127_1894488_25 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000002142 205.0
TLS3_k127_1894488_26 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000004139 196.0
TLS3_k127_1894488_27 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000003962 179.0
TLS3_k127_1894488_28 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000008094 149.0
TLS3_k127_1894488_29 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000001172 131.0
TLS3_k127_1894488_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 4.157e-197 626.0
TLS3_k127_1894488_30 NMT1-like family - - - 0.00000000000000000000000000001417 130.0
TLS3_k127_1894488_31 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000003991 123.0
TLS3_k127_1894488_32 Polymer-forming cytoskeletal - - - 0.0000000000000000000004438 102.0
TLS3_k127_1894488_33 PFAM Archease protein family (DUF101 UPF0211) - - - 0.0000000000000000000005841 100.0
TLS3_k127_1894488_34 EamA-like transporter family - - - 0.000000000000000001379 96.0
TLS3_k127_1894488_35 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000001796 81.0
TLS3_k127_1894488_36 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000587 65.0
TLS3_k127_1894488_37 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000033 57.0
TLS3_k127_1894488_38 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03789,K03790,K03896 - 2.3.1.102,2.3.1.128 0.000001104 50.0
TLS3_k127_1894488_39 NMT1-like family K02051 - - 0.0003791 49.0
TLS3_k127_1894488_4 ethanolamine utilization protein K04019 GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 586.0
TLS3_k127_1894488_5 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 557.0
TLS3_k127_1894488_6 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007237 546.0
TLS3_k127_1894488_7 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 530.0
TLS3_k127_1931194_0 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000003686 227.0
TLS3_k127_1931194_1 Alpha/beta hydrolase of unknown function (DUF1100) K06889 - - 0.000000000000000000000000000001896 133.0
TLS3_k127_1931194_2 PFAM acyl-CoA dehydrogenase domain protein K00249,K06445 - 1.3.8.7 0.0001028 45.0
TLS3_k127_1946467_0 ATP-grasp domain K01905,K22224 - 6.2.1.13 1.058e-309 975.0
TLS3_k127_1946467_1 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 459.0
TLS3_k127_1946467_10 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000005055 233.0
TLS3_k127_1946467_11 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000001106 194.0
TLS3_k127_1946467_12 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.000000000000000000000000000000000000000000000000008672 193.0
TLS3_k127_1946467_13 PFAM Bile acid sodium symporter K03325 - - 0.0000000000000000000000000000000000000000000000038 176.0
TLS3_k127_1946467_14 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000915 181.0
TLS3_k127_1946467_15 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000000000000000000003239 168.0
TLS3_k127_1946467_16 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000001588 149.0
TLS3_k127_1946467_17 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000001629 143.0
TLS3_k127_1946467_18 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000001305 149.0
TLS3_k127_1946467_19 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000009087 134.0
TLS3_k127_1946467_2 Belongs to the UbiD family K03182,K16874 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 449.0
TLS3_k127_1946467_20 Could be involved in septation K06412 - - 0.000000000000000000000000000000001199 132.0
TLS3_k127_1946467_21 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000001384 108.0
TLS3_k127_1946467_22 Predicted membrane protein (DUF2232) - - - 0.0000000000000000000000004613 116.0
TLS3_k127_1946467_23 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000006045 94.0
TLS3_k127_1946467_24 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000838 95.0
TLS3_k127_1946467_25 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000000000005207 89.0
TLS3_k127_1946467_26 DNA binding domain, excisionase family - - - 0.000000002986 61.0
TLS3_k127_1946467_27 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.0003164 52.0
TLS3_k127_1946467_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 419.0
TLS3_k127_1946467_4 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 360.0
TLS3_k127_1946467_5 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 374.0
TLS3_k127_1946467_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009065 314.0
TLS3_k127_1946467_7 Pfam Cupin K00450,K11948 - 1.13.11.38,1.13.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003274 284.0
TLS3_k127_1946467_8 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000002023 267.0
TLS3_k127_1946467_9 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000005859 232.0
TLS3_k127_1947392_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009359 447.0
TLS3_k127_1947392_1 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005349 309.0
TLS3_k127_1947392_2 NMT1-like family K02051 - - 0.0000000001512 68.0
TLS3_k127_1947392_3 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate K07749 - 2.8.3.16 0.000000001132 60.0
TLS3_k127_1976113_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.841e-214 674.0
TLS3_k127_1976113_1 amino acid K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 551.0
TLS3_k127_1976113_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 381.0
TLS3_k127_1976113_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000002838 240.0
TLS3_k127_1976113_4 aldehyde oxidase and xanthine dehydrogenase a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000001001 209.0
TLS3_k127_1976113_5 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000616 199.0
TLS3_k127_1976113_6 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000006553 172.0
TLS3_k127_1976113_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000001061 103.0
TLS3_k127_1976113_8 Transcription factor zinc-finger K09981 - - 0.00000000000001733 76.0
TLS3_k127_2066535_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000004188 192.0
TLS3_k127_2066535_1 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000004701 86.0
TLS3_k127_2066535_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000001356 61.0
TLS3_k127_2066535_3 thiamine-containing compound biosynthetic process K02051 - - 0.0001872 48.0
TLS3_k127_2067708_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 372.0
TLS3_k127_2067708_1 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000001496 142.0
TLS3_k127_2076606_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K16874 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 358.0
TLS3_k127_2076606_1 Belongs to the UbiD family K16874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 335.0
TLS3_k127_2076606_2 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004428 255.0
TLS3_k127_2076606_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000003882 209.0
TLS3_k127_2076606_4 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000002125 171.0
TLS3_k127_2076606_5 CO dehydrogenase flavoprotein C-terminal domain - - - 0.00000000000000000000000000000000000000003334 158.0
TLS3_k127_2076606_6 NMT1-like family - - - 0.000000000001722 79.0
TLS3_k127_2100056_0 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 314.0
TLS3_k127_2100056_1 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000002189 165.0
TLS3_k127_2100056_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000243 121.0
TLS3_k127_2100056_3 - - - - 0.0000000003762 72.0
TLS3_k127_2100056_4 PFAM Aldehyde dehydrogenase K00130,K00135 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.1.8 0.00000002586 57.0
TLS3_k127_2101646_0 aconitate hydratase K01681 - 4.2.1.3 0.0 1175.0
TLS3_k127_2101646_1 PAS domain K13598 - 2.7.13.3 1.317e-212 683.0
TLS3_k127_2101646_10 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 320.0
TLS3_k127_2101646_11 PFAM ADP-ribosylation Crystallin J1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 298.0
TLS3_k127_2101646_12 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002213 281.0
TLS3_k127_2101646_13 ATP cone domain K07738 - - 0.0000000000000000000000000000000000000000000000000000000000007169 214.0
TLS3_k127_2101646_14 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000005578 207.0
TLS3_k127_2101646_15 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000005584 185.0
TLS3_k127_2101646_16 TIGRFAM sugar-phosphate isomerase, RpiB LacA LacB family K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000003474 179.0
TLS3_k127_2101646_17 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000001757 183.0
TLS3_k127_2101646_18 serine-type endopeptidase activity K04691,K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000009184 171.0
TLS3_k127_2101646_19 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000002789 165.0
TLS3_k127_2101646_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 609.0
TLS3_k127_2101646_20 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000007253 163.0
TLS3_k127_2101646_21 iron ion binding - - - 0.000000000000000000000000000000000000008456 151.0
TLS3_k127_2101646_22 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000009626 143.0
TLS3_k127_2101646_23 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000005476 106.0
TLS3_k127_2101646_24 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000002271 109.0
TLS3_k127_2101646_25 Protein of unknown function (DUF2905) - - - 0.0000000000000000000001102 102.0
TLS3_k127_2101646_26 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000006351 92.0
TLS3_k127_2101646_27 Ribosomal L32p protein family K02911 - - 0.0000000000000001237 80.0
TLS3_k127_2101646_28 Histidine kinase - - - 0.000001283 53.0
TLS3_k127_2101646_29 hydrolase activity, hydrolyzing O-glycosyl compounds K05343 - 3.2.1.1,5.4.99.16 0.00009202 45.0
TLS3_k127_2101646_3 protein-containing complex disassembly K02837,K07133 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 567.0
TLS3_k127_2101646_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 484.0
TLS3_k127_2101646_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 480.0
TLS3_k127_2101646_6 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535,K13599 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 389.0
TLS3_k127_2101646_7 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 364.0
TLS3_k127_2101646_8 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 352.0
TLS3_k127_2101646_9 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 338.0
TLS3_k127_2128766_0 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 333.0
TLS3_k127_2128766_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009248 303.0
TLS3_k127_2128766_2 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000002451 103.0
TLS3_k127_2128766_3 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000000002845 96.0
TLS3_k127_2128766_4 Metallo-beta-lactamase superfamily - - - 0.00000000000006856 82.0
TLS3_k127_2128766_5 NMT1-like family K02051 - - 0.000003771 58.0
TLS3_k127_2128766_6 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 GO:0003674,GO:0003824,GO:0005488,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:0071890,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 0.000004044 51.0
TLS3_k127_2149278_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.656e-305 947.0
TLS3_k127_2149278_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 572.0
TLS3_k127_2149278_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000002198 215.0
TLS3_k127_2149278_3 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.000000000000000000000000000000000000000000000001203 183.0
TLS3_k127_2149278_4 NMT1-like family K02051 - - 0.0000000000000000000001248 109.0
TLS3_k127_2149278_5 NMT1-like family K02051 - - 0.00000000000000000004299 102.0
TLS3_k127_2177933_0 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000004593 253.0
TLS3_k127_2177933_1 Thioredoxin K03671,K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000003042 229.0
TLS3_k127_2177933_2 OsmC-like protein - - - 0.0000000007431 61.0
TLS3_k127_2177933_3 OsmC-like protein - - - 0.0000000008536 63.0
TLS3_k127_2177933_4 3-oxoadipate enol-lactonase K01055 - 3.1.1.24 0.000002366 53.0
TLS3_k127_2191591_0 transcription factor binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 481.0
TLS3_k127_2191591_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 357.0
TLS3_k127_2191591_2 Uncharacterized conserved protein (DUF2183) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 346.0
TLS3_k127_2191591_3 Rossmann-like domain K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000001576 267.0
TLS3_k127_2191591_4 Secreted and surface protein containing fasciclin-like repeats - - - 0.00000000000000000000000000000000000000000000000000005511 191.0
TLS3_k127_2191591_5 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000003507 126.0
TLS3_k127_2191591_6 Enoyl-(Acyl carrier protein) reductase K00046,K00059 - 1.1.1.100,1.1.1.69 0.0001124 46.0
TLS3_k127_2216222_0 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 379.0
TLS3_k127_2216222_1 PFAM amidohydrolase 2 K10220,K14333 - 4.1.1.46,4.2.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 336.0
TLS3_k127_2216222_2 His Kinase A (phosphoacceptor) domain K20971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 323.0
TLS3_k127_2216222_3 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000005563 145.0
TLS3_k127_2219246_0 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000000000000000000000000000000000001066 207.0
TLS3_k127_2219246_1 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000000000000009891 166.0
TLS3_k127_2219246_2 GDP-mannose mannosyl hydrolase activity K00077,K01092,K03574 - 1.1.1.169,3.1.3.25,3.6.1.55 0.00000000000000000000000000000001771 134.0
TLS3_k127_2219246_3 Beta-lactamase - - - 0.0000000000000000002663 91.0
TLS3_k127_2219246_4 - - - - 0.0000000000000006298 81.0
TLS3_k127_2219246_5 PQ loop repeat K15383 - - 0.000005658 49.0
TLS3_k127_2219246_6 Beta-lactamase - - - 0.0008038 46.0
TLS3_k127_2234701_0 Maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003139 284.0
TLS3_k127_2234701_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003633 273.0
TLS3_k127_2234701_2 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000001214 124.0
TLS3_k127_2234701_3 DUF218 domain - - - 0.00000000000000000000000005144 117.0
TLS3_k127_232052_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 512.0
TLS3_k127_232052_1 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000004834 213.0
TLS3_k127_2348761_0 Glycogen debranching enzyme - - - 1.48e-266 844.0
TLS3_k127_2348761_1 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 3.147e-254 797.0
TLS3_k127_2348761_10 IMP dehydrogenase activity - - - 0.000000000000000000004894 94.0
TLS3_k127_2348761_11 nuclear chromosome segregation - - - 0.0000000000000000001562 96.0
TLS3_k127_2348761_12 Belongs to the ompA family - - - 0.000000000000002509 86.0
TLS3_k127_2348761_13 cheY-homologous receiver domain - - - 0.000000000000008553 80.0
TLS3_k127_2348761_14 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.0000001789 52.0
TLS3_k127_2348761_15 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.000001938 59.0
TLS3_k127_2348761_16 ABC transporter substrate-binding protein K15551 - - 0.00002988 55.0
TLS3_k127_2348761_2 Sigma-54 interaction domain K07714,K07715 - - 8.051e-194 615.0
TLS3_k127_2348761_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 456.0
TLS3_k127_2348761_4 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 419.0
TLS3_k127_2348761_5 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 313.0
TLS3_k127_2348761_6 acetamidase formamidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 297.0
TLS3_k127_2348761_7 KR domain K03366 - 1.1.1.304,1.1.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000001812 262.0
TLS3_k127_2348761_8 Lactoylglutathione lyase K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000006962 228.0
TLS3_k127_2348761_9 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000002232 157.0
TLS3_k127_2356574_0 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008908 509.0
TLS3_k127_2356574_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001463 229.0
TLS3_k127_2356574_2 nickel-responsive regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000003237 128.0
TLS3_k127_2356574_3 MotA/TolQ/ExbB proton channel family K03561 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000002057 81.0
TLS3_k127_2409147_0 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 367.0
TLS3_k127_2409147_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002035 271.0
TLS3_k127_2409147_10 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000896 94.0
TLS3_k127_2409147_11 - - - - 0.000000000000000003785 89.0
TLS3_k127_2409147_12 Catalyzes the transfer of an acetyl group from acetyl- CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring K18816 - 2.3.1.82 0.000000000000000006347 86.0
TLS3_k127_2409147_13 - - - - 0.000000005438 59.0
TLS3_k127_2409147_14 - - - - 0.000000007478 58.0
TLS3_k127_2409147_2 Phosphoglycerate mutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008793 256.0
TLS3_k127_2409147_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002413 249.0
TLS3_k127_2409147_4 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003363 242.0
TLS3_k127_2409147_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000001817 217.0
TLS3_k127_2409147_6 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls - - - 0.000000000000000000000000000000000000000000000000000000000002002 226.0
TLS3_k127_2409147_7 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000000000000000000000000000000004316 169.0
TLS3_k127_2409147_8 SnoaL-like domain K06893 - - 0.000000000000000000000000000000000000302 145.0
TLS3_k127_2409147_9 Tyrosine phosphatase family - - - 0.00000000000000000000003533 105.0
TLS3_k127_243838_0 Integral membrane sensor signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 336.0
TLS3_k127_243838_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002803 247.0
TLS3_k127_243838_2 lysyltransferase activity - - - 0.00000000000000000000002878 111.0
TLS3_k127_243838_3 - - - - 0.0000000000000000634 82.0
TLS3_k127_2501369_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 5.129e-273 848.0
TLS3_k127_2501369_1 Required for chromosome condensation and partitioning K03529 - - 1.83e-214 708.0
TLS3_k127_2501369_10 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 330.0
TLS3_k127_2501369_11 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 319.0
TLS3_k127_2501369_12 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 320.0
TLS3_k127_2501369_13 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001436 278.0
TLS3_k127_2501369_14 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000007796 270.0
TLS3_k127_2501369_15 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001609 265.0
TLS3_k127_2501369_16 carboxypeptidase activity K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000001081 247.0
TLS3_k127_2501369_17 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000005673 250.0
TLS3_k127_2501369_18 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000000001105 201.0
TLS3_k127_2501369_19 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000001562 191.0
TLS3_k127_2501369_2 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 541.0
TLS3_k127_2501369_20 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000009761 181.0
TLS3_k127_2501369_22 Pfam:Methyltransf_26 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000005954 157.0
TLS3_k127_2501369_23 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000001263 151.0
TLS3_k127_2501369_24 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000001446 153.0
TLS3_k127_2501369_25 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity K00950,K13940 - 2.7.6.3,4.1.2.25 0.0000000000000000000000000000000000000002787 154.0
TLS3_k127_2501369_26 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000004699 154.0
TLS3_k127_2501369_27 Domain of unknown function (DUF1992) - - - 0.0000000000000000000000000000418 121.0
TLS3_k127_2501369_28 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000006275 117.0
TLS3_k127_2501369_29 YacP-like NYN domain K06962 - - 0.00000000000000000000000004073 114.0
TLS3_k127_2501369_3 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 524.0
TLS3_k127_2501369_30 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000001878 107.0
TLS3_k127_2501369_31 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000006665 100.0
TLS3_k127_2501369_32 Belongs to the UPF0109 family K06960 - - 0.00000000000000000002215 93.0
TLS3_k127_2501369_33 Nitroreductase family - - - 0.0000000000000000007662 94.0
TLS3_k127_2501369_34 Protein of unknown function (DUF507) - - - 0.00000000000003457 78.0
TLS3_k127_2501369_35 Protein of unknown function (DUF502) - - - 0.00000000003036 71.0
TLS3_k127_2501369_36 Polymer-forming cytoskeletal - - - 0.0000001665 58.0
TLS3_k127_2501369_37 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.00002461 49.0
TLS3_k127_2501369_38 - - - - 0.000135 51.0
TLS3_k127_2501369_4 PFAM AAA ATPase central domain protein K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 511.0
TLS3_k127_2501369_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 498.0
TLS3_k127_2501369_6 Mur ligase, middle domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 448.0
TLS3_k127_2501369_7 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 447.0
TLS3_k127_2501369_8 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 437.0
TLS3_k127_2501369_9 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 428.0
TLS3_k127_2532979_0 Histidine kinase K07716 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000001744 219.0
TLS3_k127_254954_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2099.0
TLS3_k127_254954_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1918.0
TLS3_k127_254954_10 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 336.0
TLS3_k127_254954_11 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 323.0
TLS3_k127_254954_12 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 312.0
TLS3_k127_254954_13 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 297.0
TLS3_k127_254954_14 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 302.0
TLS3_k127_254954_15 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002413 286.0
TLS3_k127_254954_16 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003344 270.0
TLS3_k127_254954_17 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001147 269.0
TLS3_k127_254954_18 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002551 266.0
TLS3_k127_254954_19 PFAM ABC transporter related K01990,K09691,K09693 - 3.6.3.40 0.000000000000000000000000000000000000000000000000000000000000000000000002322 254.0
TLS3_k127_254954_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1092.0
TLS3_k127_254954_20 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000004651 245.0
TLS3_k127_254954_21 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000002201 241.0
TLS3_k127_254954_22 Belongs to the universal ribosomal protein uS5 family K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000008048 231.0
TLS3_k127_254954_23 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000008562 222.0
TLS3_k127_254954_24 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000002875 248.0
TLS3_k127_254954_25 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000001949 218.0
TLS3_k127_254954_26 PFAM permease YjgP YjgQ family protein K07091 - - 0.00000000000000000000000000000000000000000000000000000000000002459 229.0
TLS3_k127_254954_27 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000002755 216.0
TLS3_k127_254954_28 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001066 211.0
TLS3_k127_254954_29 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000001517 203.0
TLS3_k127_254954_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 3.078e-220 687.0
TLS3_k127_254954_30 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002691 204.0
TLS3_k127_254954_31 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000158 198.0
TLS3_k127_254954_32 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000000000003632 200.0
TLS3_k127_254954_33 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000002604 198.0
TLS3_k127_254954_34 Transport permease protein K01992,K09690 - - 0.0000000000000000000000000000000000000000000000000001362 196.0
TLS3_k127_254954_35 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000004805 184.0
TLS3_k127_254954_36 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000002269 174.0
TLS3_k127_254954_37 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000001921 173.0
TLS3_k127_254954_38 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000002008 168.0
TLS3_k127_254954_39 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000001433 163.0
TLS3_k127_254954_4 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 6.942e-196 618.0
TLS3_k127_254954_40 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000001991 161.0
TLS3_k127_254954_41 permease YjgP YjgQ family K11720 - - 0.0000000000000000000000000000000000000003664 162.0
TLS3_k127_254954_42 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00042 - 1.1.1.60 0.000000000000000000000000000000000000001777 158.0
TLS3_k127_254954_43 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000004415 148.0
TLS3_k127_254954_44 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000004625 148.0
TLS3_k127_254954_45 - - - - 0.0000000000000000000000000000000000002158 146.0
TLS3_k127_254954_46 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000007956 143.0
TLS3_k127_254954_47 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000005336 134.0
TLS3_k127_254954_48 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000003531 134.0
TLS3_k127_254954_49 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000206 135.0
TLS3_k127_254954_5 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 582.0
TLS3_k127_254954_50 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000002049 119.0
TLS3_k127_254954_51 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000001072 108.0
TLS3_k127_254954_52 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001159 106.0
TLS3_k127_254954_53 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000001214 92.0
TLS3_k127_254954_55 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000003003 78.0
TLS3_k127_254954_56 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000001504 68.0
TLS3_k127_254954_57 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000001309 65.0
TLS3_k127_254954_58 COG3806 Anti-sigma factor K07167 - - 0.000000001107 65.0
TLS3_k127_254954_59 peptidoglycan binding K02520,K03749,K06204,K16291 - - 0.0000001555 61.0
TLS3_k127_254954_6 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 568.0
TLS3_k127_254954_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 437.0
TLS3_k127_254954_8 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 376.0
TLS3_k127_254954_9 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 351.0
TLS3_k127_2610007_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 8.89e-256 797.0
TLS3_k127_2610007_1 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002138 238.0
TLS3_k127_2610007_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000003208 148.0
TLS3_k127_2610007_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000006025 149.0
TLS3_k127_2610007_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000266 136.0
TLS3_k127_2610007_5 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000000000002005 128.0
TLS3_k127_2610007_6 Histidine kinase - - - 0.000000000000000000000000001205 117.0
TLS3_k127_2610007_7 Cytochrome c K12263 - - 0.000000000000000003832 90.0
TLS3_k127_2645543_0 TOBE domain K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000005804 241.0
TLS3_k127_2645543_1 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000002409 192.0
TLS3_k127_2645543_2 ABC-type Fe3 transport system permease component K02011 - - 0.0000000000000000000000126 106.0
TLS3_k127_2645543_3 endonuclease exonuclease phosphatase - - - 0.0000000000000000000002162 107.0
TLS3_k127_2645543_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11072 - 3.6.3.31 0.00000000000000007296 86.0
TLS3_k127_2645543_5 Belongs to the ABC transporter superfamily - - - 0.000008203 51.0
TLS3_k127_2645543_6 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0001414 46.0
TLS3_k127_2705792_0 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 462.0
TLS3_k127_2705792_1 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000000000000000000000000000000000000000000001407 186.0
TLS3_k127_2705792_2 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000002913 173.0
TLS3_k127_2705792_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000852 169.0
TLS3_k127_2705792_4 Cytochrome c K12263 - - 0.00000004005 59.0
TLS3_k127_2712976_0 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000003425 153.0
TLS3_k127_2712976_1 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000001798 130.0
TLS3_k127_2712976_2 PFAM blue (type 1) copper domain protein - - - 0.0000000000002577 76.0
TLS3_k127_2712976_3 Transcription factor zinc-finger K09981 - - 0.0000000005772 64.0
TLS3_k127_2781662_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000007124 237.0
TLS3_k127_2781662_1 Diguanylate cyclase K21084 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000001578 233.0
TLS3_k127_2781662_2 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000001452 119.0
TLS3_k127_2781662_3 HlyD family secretion protein K02005 - - 0.00000005602 57.0
TLS3_k127_2781662_4 HlyD family secretion protein K02005 - - 0.0000001014 55.0
TLS3_k127_2781662_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000003179 53.0
TLS3_k127_2781662_6 HlyD family secretion protein K02005 - - 0.00001323 47.0
TLS3_k127_2805514_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008975 320.0
TLS3_k127_2805514_1 ABC transporter, ATP-binding protein K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000002829 185.0
TLS3_k127_2805514_2 Elements of external origin - - - 0.00000000001201 67.0
TLS3_k127_2862006_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.34e-269 842.0
TLS3_k127_2862006_1 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 566.0
TLS3_k127_2862006_2 abc transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007709 307.0
TLS3_k127_2862006_3 abc transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 306.0
TLS3_k127_2862006_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 294.0
TLS3_k127_2862006_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000833 170.0
TLS3_k127_2862006_6 - - - - 0.000000000000000000000000001017 117.0
TLS3_k127_2883856_0 SNF2 family N-terminal domain - - - 6.316e-299 951.0
TLS3_k127_2883856_1 Tripartite tricarboxylate transporter TctA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 579.0
TLS3_k127_2883856_2 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000002898 181.0
TLS3_k127_2883856_3 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.00000000005202 74.0
TLS3_k127_2887843_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 3.264e-199 644.0
TLS3_k127_2887843_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002041 274.0
TLS3_k127_2887843_10 Bacterial extracellular solute-binding protein - - - 0.00000000008065 72.0
TLS3_k127_2887843_2 metal-dependent hydrolase of the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000657 246.0
TLS3_k127_2887843_3 Amino-transferase class IV - - - 0.00000000000000000000000000000000000000000000000000000000000001374 227.0
TLS3_k127_2887843_4 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000004484 201.0
TLS3_k127_2887843_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.0000000000000000000000000000001759 131.0
TLS3_k127_2887843_6 protein conserved in bacteria - - - 0.000000000000000000000000002302 124.0
TLS3_k127_2887843_7 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.00000000000000000000002831 106.0
TLS3_k127_2887843_8 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000002187 93.0
TLS3_k127_2887843_9 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000003894 75.0
TLS3_k127_2888220_0 AMP-binding enzyme C-terminal domain K02363,K04116 - 2.7.7.58,6.3.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 330.0
TLS3_k127_2888220_1 Cyclodeaminase K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000002171 226.0
TLS3_k127_2888220_2 Fumarate reductase flavoprotein C-term - - - 0.0000000000000000000000000000000000002016 160.0
TLS3_k127_2888220_3 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388,K03616 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000108 71.0
TLS3_k127_289226_0 RNA polymerase I subunit A N-terminus K03046 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 608.0
TLS3_k127_289226_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 475.0
TLS3_k127_289226_2 With S4 and S5 plays an important role in translational accuracy K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000007325 223.0
TLS3_k127_289226_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000001236 218.0
TLS3_k127_2925840_0 PhoPQ-activated pathogenicity-related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 440.0
TLS3_k127_2925840_1 ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000007914 175.0
TLS3_k127_2925840_2 methyltransferase - - - 0.00000000000000000000000000000000000000001584 164.0
TLS3_k127_2925840_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000009347 121.0
TLS3_k127_2952650_0 TRAP transporter, 4TM 12TM fusion protein - - - 7.651e-195 627.0
TLS3_k127_2952650_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 537.0
TLS3_k127_2952650_10 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000008651 116.0
TLS3_k127_2952650_11 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000001117 92.0
TLS3_k127_2952650_12 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000006007 81.0
TLS3_k127_2952650_13 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000001071 81.0
TLS3_k127_2952650_14 Chemotaxis protein CheY - - - 0.0000000000002262 76.0
TLS3_k127_2952650_15 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000000131 75.0
TLS3_k127_2952650_16 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000386 51.0
TLS3_k127_2952650_2 Histidine kinase K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 328.0
TLS3_k127_2952650_3 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 299.0
TLS3_k127_2952650_4 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002938 272.0
TLS3_k127_2952650_5 Peptidase family M23 K21472 - - 0.0000000000000000000000000000000000000000000000000000000007547 206.0
TLS3_k127_2952650_6 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.000000000000000000000000000000000000000000000000000001806 202.0
TLS3_k127_2952650_7 thiamine-containing compound biosynthetic process - - - 0.0000000000000000000000000000000000000000000202 176.0
TLS3_k127_2952650_8 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000005601 151.0
TLS3_k127_2952650_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000007655 110.0
TLS3_k127_3032530_0 PFAM ABC transporter related K06147 - - 3.879e-215 686.0
TLS3_k127_3032530_1 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046421,GO:0046487,GO:0071704,GO:0072350 4.1.3.1 4.477e-206 668.0
TLS3_k127_3032530_10 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000000000000000000000000009051 187.0
TLS3_k127_3032530_11 PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000001064 181.0
TLS3_k127_3032530_12 TspO/MBR family K05770 - - 0.000000000000000000000000000000000000000001143 160.0
TLS3_k127_3032530_14 decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000000000000005743 141.0
TLS3_k127_3032530_15 GYD domain - - - 0.0000000000000000000000000000000002552 134.0
TLS3_k127_3032530_16 - - - - 0.0000000000000000168 89.0
TLS3_k127_3032530_17 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.0000000000000000168 89.0
TLS3_k127_3032530_18 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.000000000000248 75.0
TLS3_k127_3032530_19 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000005997 73.0
TLS3_k127_3032530_2 obsolete transcription factor activity, core RNA polymerase II binding K06959 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - 1.557e-204 644.0
TLS3_k127_3032530_20 peptidyl-arginine hydroxylation - - - 0.00002852 48.0
TLS3_k127_3032530_3 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 440.0
TLS3_k127_3032530_4 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 318.0
TLS3_k127_3032530_5 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008505 284.0
TLS3_k127_3032530_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001204 275.0
TLS3_k127_3032530_7 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000001039 224.0
TLS3_k127_3032530_8 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000003562 216.0
TLS3_k127_3032530_9 Protein of unknown function (DUF1275) - - - 0.0000000000000000000000000000000000000000000000000000001522 203.0
TLS3_k127_304359_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 2.857e-223 706.0
TLS3_k127_304359_1 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 544.0
TLS3_k127_304359_10 Enoyl-(Acyl carrier protein) reductase K00059,K19550 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000003456 226.0
TLS3_k127_304359_11 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000001809 208.0
TLS3_k127_304359_12 Conserved TM helix - - - 0.00000000000000000000000000000000000000000000003205 181.0
TLS3_k127_304359_13 Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000008635 166.0
TLS3_k127_304359_14 Acts as a magnesium transporter K06213 - - 0.0000000000000000000006589 107.0
TLS3_k127_304359_15 Putative regulatory protein - - - 0.00000000000000000002421 93.0
TLS3_k127_304359_16 - - - - 0.000000000000000008249 88.0
TLS3_k127_304359_18 Iron-containing redox enzyme K06137 - 1.3.3.11 0.00000007967 62.0
TLS3_k127_304359_19 SMP-30/Gluconolaconase/LRE-like region - - - 0.00006219 55.0
TLS3_k127_304359_2 Belongs to the UbiD family K03182,K16874 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 458.0
TLS3_k127_304359_20 Cupin - - - 0.00007601 50.0
TLS3_k127_304359_3 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 410.0
TLS3_k127_304359_4 amine dehydrogenase activity K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 376.0
TLS3_k127_304359_5 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 368.0
TLS3_k127_304359_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 369.0
TLS3_k127_304359_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 363.0
TLS3_k127_304359_8 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 294.0
TLS3_k127_304359_9 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002412 254.0
TLS3_k127_3054687_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 616.0
TLS3_k127_3054687_1 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 360.0
TLS3_k127_3054687_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009665 275.0
TLS3_k127_3054687_3 Sugar fermentation stimulation protein K06206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001253 260.0
TLS3_k127_3054687_4 DoxX K15977,K16937 - 1.8.5.2 0.0000000000000000000000000000000000000000000000000000000007133 207.0
TLS3_k127_3054687_5 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000001269 201.0
TLS3_k127_3088290_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.404e-207 660.0
TLS3_k127_3088290_1 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 566.0
TLS3_k127_3088290_10 Scavenger mRNA decapping enzyme C-term binding K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000002154 184.0
TLS3_k127_3088290_11 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000002715 185.0
TLS3_k127_3088290_12 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000000001044 113.0
TLS3_k127_3088290_13 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K14161 - 2.7.7.7 0.0000000000000000001287 91.0
TLS3_k127_3088290_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 468.0
TLS3_k127_3088290_3 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 401.0
TLS3_k127_3088290_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 371.0
TLS3_k127_3088290_5 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 300.0
TLS3_k127_3088290_6 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000001938 248.0
TLS3_k127_3088290_7 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000001272 250.0
TLS3_k127_3088290_8 Cytidylate kinase K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000001799 222.0
TLS3_k127_3088290_9 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553,K14160 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000001474 212.0
TLS3_k127_3109110_0 ethanolamine utilization protein K04019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 313.0
TLS3_k127_3109110_1 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000001669 119.0
TLS3_k127_3109110_10 Winged helix-turn helix - - - 0.00002022 54.0
TLS3_k127_3109110_2 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000001058 110.0
TLS3_k127_3109110_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000002476 106.0
TLS3_k127_3109110_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000002873 83.0
TLS3_k127_3109110_5 NMT1-like family K02051 - - 0.0000000000000009759 89.0
TLS3_k127_3109110_6 Bacterial extracellular solute-binding protein K02012 - - 0.00000000003727 70.0
TLS3_k127_3109110_7 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0000000162 64.0
TLS3_k127_3109110_8 Iron-containing redox enzyme K06137 - 1.3.3.11 0.00000004259 63.0
TLS3_k127_3109110_9 ABC transporter substrate-binding protein K02051 - - 0.00001041 57.0
TLS3_k127_311272_0 PFAM Conserved carboxylase region K01571,K01960 - 4.1.1.3,6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 565.0
TLS3_k127_311272_1 ATPase associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 432.0
TLS3_k127_311272_2 ethanolamine utilization protein K04019 GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 422.0
TLS3_k127_311272_3 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 385.0
TLS3_k127_311272_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009274 310.0
TLS3_k127_311272_5 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000863 254.0
TLS3_k127_311272_6 Tetratricopeptide repeat - - - 0.00000000000000000000001815 110.0
TLS3_k127_311272_7 Glucose / Sorbosone dehydrogenase K00117,K21430 - 1.1.5.2 0.0000000000000006159 78.0
TLS3_k127_311272_9 4Fe-4S binding domain K00395,K02572,K03616 - 1.8.99.2 0.000001395 58.0
TLS3_k127_31240_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 541.0
TLS3_k127_31240_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 350.0
TLS3_k127_31240_2 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 334.0
TLS3_k127_31240_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 299.0
TLS3_k127_31240_4 Family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001096 276.0
TLS3_k127_31240_5 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000008161 253.0
TLS3_k127_31240_6 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000001398 249.0
TLS3_k127_31240_7 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000001272 175.0
TLS3_k127_3195991_0 Biotin carboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 491.0
TLS3_k127_3195991_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000007137 132.0
TLS3_k127_3195991_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000001828 122.0
TLS3_k127_320586_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1285.0
TLS3_k127_320586_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 514.0
TLS3_k127_320586_10 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000007686 173.0
TLS3_k127_320586_11 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0000000000000000000000000000000003844 141.0
TLS3_k127_320586_12 Cupin - - - 0.00000000000000001962 88.0
TLS3_k127_320586_13 TIGRFAM Taurine ABC transporter, periplasmic binding protein K15551 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009970,GO:0009987,GO:0009991,GO:0015711,GO:0015734,GO:0015849,GO:0030288,GO:0030313,GO:0031667,GO:0031668,GO:0031669,GO:0031975,GO:0033554,GO:0042594,GO:0042597,GO:0042908,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0071496,GO:0071702,GO:0071705,GO:0072348 - 0.000005823 58.0
TLS3_k127_320586_14 Lipid A biosynthesis K02517 - 2.3.1.241 0.00007176 54.0
TLS3_k127_320586_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 361.0
TLS3_k127_320586_3 TIM-barrel fold metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 324.0
TLS3_k127_320586_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 298.0
TLS3_k127_320586_5 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004324 269.0
TLS3_k127_320586_6 TIM-barrel fold metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002709 257.0
TLS3_k127_320586_7 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000223 213.0
TLS3_k127_320586_8 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000007104 199.0
TLS3_k127_320586_9 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000004372 191.0
TLS3_k127_3276969_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 5.949e-229 734.0
TLS3_k127_3276969_1 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000003609 211.0
TLS3_k127_3276969_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000003807 94.0
TLS3_k127_3276969_3 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.000000000000685 74.0
TLS3_k127_3276969_4 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0006317 43.0
TLS3_k127_3306356_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01577,K01652,K03852 - 2.2.1.6,2.3.3.15,4.1.1.8 3.797e-196 625.0
TLS3_k127_3306356_1 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 397.0
TLS3_k127_3306356_2 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000901 181.0
TLS3_k127_3306356_3 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.0000000000000000001475 90.0
TLS3_k127_3309906_0 Amidohydrolase K03392,K22213 - 4.1.1.45,4.1.1.52 0.000000000000000000000000000454 126.0
TLS3_k127_3309906_1 Lipid A 3-O-deacylase (PagL) - - - 0.0000000000000000000005013 106.0
TLS3_k127_3309906_2 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.00000000004797 74.0
TLS3_k127_3309906_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.00000002337 61.0
TLS3_k127_3492491_0 S-adenosyl-L-methionine-dependent methyltransferase K00773 - 2.4.2.29 4.449e-292 912.0
TLS3_k127_3492491_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 7.711e-281 874.0
TLS3_k127_3492491_10 ornithine cyclodeaminase K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 343.0
TLS3_k127_3492491_11 Mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 336.0
TLS3_k127_3492491_12 MltA specific insert domain K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 306.0
TLS3_k127_3492491_13 Ornithine cyclodeaminase/mu-crystallin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009111 293.0
TLS3_k127_3492491_14 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 286.0
TLS3_k127_3492491_15 base-excision repair K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002449 286.0
TLS3_k127_3492491_16 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003381 283.0
TLS3_k127_3492491_17 PFAM Ribonuclease BN-like family K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003991 268.0
TLS3_k127_3492491_18 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006822 265.0
TLS3_k127_3492491_19 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000009281 263.0
TLS3_k127_3492491_2 Domain of Unknown Function (DUF748) - - - 7.904e-244 795.0
TLS3_k127_3492491_20 cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005298 261.0
TLS3_k127_3492491_21 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000001339 246.0
TLS3_k127_3492491_22 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000003865 225.0
TLS3_k127_3492491_23 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000004058 224.0
TLS3_k127_3492491_24 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - 0.00000000000000000000000000000000000000000000000000000000000002386 226.0
TLS3_k127_3492491_25 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000005916 226.0
TLS3_k127_3492491_26 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000002447 222.0
TLS3_k127_3492491_27 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000002058 217.0
TLS3_k127_3492491_28 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050,K15554 - - 0.00000000000000000000000000000000000000000000000000000000009266 216.0
TLS3_k127_3492491_29 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000003548 219.0
TLS3_k127_3492491_3 Bacterial protein of unknown function (DUF853) - - - 9.421e-223 700.0
TLS3_k127_3492491_30 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000002346 212.0
TLS3_k127_3492491_31 Sugar (and other) transporter - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000002346 209.0
TLS3_k127_3492491_32 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050,K15554 - - 0.000000000000000000000000000000000000000000000000000002015 200.0
TLS3_k127_3492491_33 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000001567 194.0
TLS3_k127_3492491_34 PFAM Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000002249 188.0
TLS3_k127_3492491_35 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000431 139.0
TLS3_k127_3492491_36 serine acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000007144 116.0
TLS3_k127_3492491_37 Zincin-like metallopeptidase - - - 0.0000000000000000000000007082 108.0
TLS3_k127_3492491_38 PFAM AIG2 family protein - - - 0.000000000000000000000007648 109.0
TLS3_k127_3492491_39 Glycine-zipper domain - - - 0.0000000000000000000006078 100.0
TLS3_k127_3492491_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.609e-214 678.0
TLS3_k127_3492491_40 NMT1-like family K02051 - - 0.000000000000000001341 94.0
TLS3_k127_3492491_41 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000005771 91.0
TLS3_k127_3492491_42 PFAM YbbR family protein - - - 0.0000000008574 70.0
TLS3_k127_3492491_43 thiamine-containing compound biosynthetic process K02051 - - 0.000000095 59.0
TLS3_k127_3492491_5 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 561.0
TLS3_k127_3492491_6 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 506.0
TLS3_k127_3492491_7 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 423.0
TLS3_k127_3492491_8 aldo-keto reductase (NADP) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 414.0
TLS3_k127_3492491_9 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 422.0
TLS3_k127_3519228_0 Putative glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 357.0
TLS3_k127_3519228_1 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 294.0
TLS3_k127_3519228_2 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000001242 255.0
TLS3_k127_3519228_3 PFAM Prenyltransferase squalene oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000001828 235.0
TLS3_k127_3519228_4 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000003643 179.0
TLS3_k127_3519228_5 Zn-dependent hydrolases of the - - - 0.000000000000000000000000000000000000000000001792 175.0
TLS3_k127_3519228_6 Evidence 5 No homology to any previously reported sequences - - - 0.0000002819 55.0
TLS3_k127_3520851_0 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 385.0
TLS3_k127_3520851_1 ABC-3 protein K09816,K09819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005043 275.0
TLS3_k127_3520851_2 PFAM ABC transporter related K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002 251.0
TLS3_k127_3520851_3 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000005416 207.0
TLS3_k127_3520851_4 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000009534 193.0
TLS3_k127_3520851_5 PFAM electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000002132 137.0
TLS3_k127_3520851_6 SCO1/SenC K07152 - - 0.00000000000000000000000000000002315 136.0
TLS3_k127_3520851_7 Periplasmic protein TonB links inner and outer membranes - - - 0.00000000002338 72.0
TLS3_k127_3520851_8 oxidase, assembly K02258 - - 0.00001268 56.0
TLS3_k127_3521658_0 Leucyl-tRNA synthetase, Domain 2 K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1125.0
TLS3_k127_3521658_1 Elongator protein 3, MiaB family, Radical SAM - - - 5.509e-316 983.0
TLS3_k127_3521658_10 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002942 248.0
TLS3_k127_3521658_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000002198 208.0
TLS3_k127_3521658_12 6,7-dimethyl-8-ribityllumazine synthase K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000006841 198.0
TLS3_k127_3521658_13 Carotenoid biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000001182 199.0
TLS3_k127_3521658_14 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000000003629 197.0
TLS3_k127_3521658_15 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000295 178.0
TLS3_k127_3521658_16 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000001221 176.0
TLS3_k127_3521658_17 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000003299 136.0
TLS3_k127_3521658_18 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000003319 89.0
TLS3_k127_3521658_19 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases - - - 0.000000000000000005492 94.0
TLS3_k127_3521658_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.068e-302 942.0
TLS3_k127_3521658_20 Aconitase C-terminal domain K01703 - 4.2.1.33,4.2.1.35 0.000000000000000009264 83.0
TLS3_k127_3521658_21 Belongs to the UPF0337 (CsbD) family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000003051 88.0
TLS3_k127_3521658_22 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000001464 77.0
TLS3_k127_3521658_24 Lipopolysaccharide-assembly - - - 0.000000000006881 74.0
TLS3_k127_3521658_25 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000009485 69.0
TLS3_k127_3521658_3 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 599.0
TLS3_k127_3521658_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 488.0
TLS3_k127_3521658_5 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 459.0
TLS3_k127_3521658_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009911 433.0
TLS3_k127_3521658_7 OB-fold nucleic acid binding domain K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000895 376.0
TLS3_k127_3521658_8 Glycosyl transferase family 21 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009776 366.0
TLS3_k127_3521658_9 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001493 254.0
TLS3_k127_3540642_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 2.519e-258 806.0
TLS3_k127_3540642_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 611.0
TLS3_k127_3540642_2 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 336.0
TLS3_k127_3540642_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 292.0
TLS3_k127_3540642_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 282.0
TLS3_k127_3540642_5 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000005932 79.0
TLS3_k127_354406_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 5.628e-231 731.0
TLS3_k127_354406_1 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 2.182e-196 617.0
TLS3_k127_354406_10 membrane-associated protein K03975 - - 0.000000000000000000000000000000002662 137.0
TLS3_k127_354406_11 Cupredoxin-like domain - - - 0.000000000000000474 87.0
TLS3_k127_354406_12 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.00000000001503 70.0
TLS3_k127_354406_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 413.0
TLS3_k127_354406_3 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 335.0
TLS3_k127_354406_4 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000005239 234.0
TLS3_k127_354406_5 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000006181 205.0
TLS3_k127_354406_6 FAD metabolic process K00953,K15429 GO:0003674,GO:0003824,GO:0003919,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042726,GO:0042727,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046443,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0070566,GO:0071704,GO:0071944,GO:0072387,GO:0072388,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.228,2.7.7.2 0.0000000000000000000000000000000000000000000000000000001203 203.0
TLS3_k127_354406_7 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000000000008832 201.0
TLS3_k127_354406_8 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000468 203.0
TLS3_k127_354406_9 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000002729 180.0
TLS3_k127_3545334_0 Glucose / Sorbosone dehydrogenase - - - 7.533e-201 634.0
TLS3_k127_3545334_1 FAD dependent oxidoreductase K09879 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 499.0
TLS3_k127_3545334_2 large terminal subunit' - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 386.0
TLS3_k127_3545334_3 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 319.0
TLS3_k127_3545334_4 lycopene cyclase - - - 0.0000000000000000000000000000000000000000000000000000002018 201.0
TLS3_k127_3545334_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000003714 143.0
TLS3_k127_3545334_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000001716 110.0
TLS3_k127_3545334_7 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 0.0000001953 60.0
TLS3_k127_3545334_8 - - - - 0.00001968 56.0
TLS3_k127_3545334_9 Transposase IS200 like K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0005081 44.0
TLS3_k127_3546853_0 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 489.0
TLS3_k127_3546853_1 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 353.0
TLS3_k127_3546853_11 AntiSigma factor - - - 0.00003625 55.0
TLS3_k127_3546853_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 346.0
TLS3_k127_3546853_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 323.0
TLS3_k127_3546853_4 Aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000001122 226.0
TLS3_k127_3546853_5 NIPSNAP - - - 0.00000000000000000000000000000000000000000000000002451 188.0
TLS3_k127_3546853_6 Cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000000297 150.0
TLS3_k127_3546853_7 Involved in chromosome partitioning - - - 0.0000000000000000000000000000000002818 141.0
TLS3_k127_3546853_8 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000006802 131.0
TLS3_k127_3546853_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000002607 127.0
TLS3_k127_3569833_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 9.466e-309 956.0
TLS3_k127_3569833_1 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 526.0
TLS3_k127_3569833_10 Peptidase family M48 - - - 0.000000000000000004276 93.0
TLS3_k127_3569833_11 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000006736 56.0
TLS3_k127_3569833_12 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K06191 - - 0.000002892 55.0
TLS3_k127_3569833_2 CBS domain containing protein K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 459.0
TLS3_k127_3569833_3 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 314.0
TLS3_k127_3569833_4 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000006279 185.0
TLS3_k127_3569833_5 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000000205 161.0
TLS3_k127_3569833_6 Domain of unknown function (DUF4212) - - - 0.0000000000000000000000000000002177 128.0
TLS3_k127_3569833_7 Major Facilitator Superfamily - - - 0.000000000000000000000000000005237 128.0
TLS3_k127_3569833_8 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.000000000000000000000000002134 118.0
TLS3_k127_3569833_9 Redoxin - - - 0.00000000000000000000003133 102.0
TLS3_k127_359616_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 537.0
TLS3_k127_359616_1 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01664 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000007068 267.0
TLS3_k127_359616_2 regulatory protein IclR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002803 247.0
TLS3_k127_359616_3 Archaea-specific editing domain of threonyl-tRNA synthetase - - - 0.000000000000000000000000002002 117.0
TLS3_k127_359616_4 COG3103 SH3 domain protein K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.00003139 54.0
TLS3_k127_359616_5 Amidohydrolase K03392 - 4.1.1.45 0.000267 45.0
TLS3_k127_3624604_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 8.162e-281 873.0
TLS3_k127_3624604_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 566.0
TLS3_k127_3624604_10 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 302.0
TLS3_k127_3624604_11 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000003481 207.0
TLS3_k127_3624604_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000003335 193.0
TLS3_k127_3624604_13 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000004758 177.0
TLS3_k127_3624604_14 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000000000000000000000000000000000001339 175.0
TLS3_k127_3624604_15 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000002358 169.0
TLS3_k127_3624604_16 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.0000000000000000000000000000001998 143.0
TLS3_k127_3624604_17 Cupin 2, conserved barrel domain protein K11312 - - 0.000000000000000000000005213 107.0
TLS3_k127_3624604_18 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000002605 100.0
TLS3_k127_3624604_19 methyltransferase activity K00587 - 2.1.1.100 0.00000000000000004457 89.0
TLS3_k127_3624604_2 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 467.0
TLS3_k127_3624604_20 AzlC protein - - - 0.00000000000000004459 90.0
TLS3_k127_3624604_21 Helix-turn-helix domain - - - 0.000000000074 65.0
TLS3_k127_3624604_22 PFAM ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.0000000001313 75.0
TLS3_k127_3624604_23 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000008337 59.0
TLS3_k127_3624604_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 450.0
TLS3_k127_3624604_4 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 447.0
TLS3_k127_3624604_5 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 386.0
TLS3_k127_3624604_6 Transposase DDE domain group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 389.0
TLS3_k127_3624604_7 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 393.0
TLS3_k127_3624604_8 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 352.0
TLS3_k127_3624604_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009236 343.0
TLS3_k127_3650036_0 histidine kinase HAMP region domain protein K07716 - 2.7.13.3 0.0 2437.0
TLS3_k127_3650036_1 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 448.0
TLS3_k127_3650036_10 - - - - 0.000000000000000000001925 96.0
TLS3_k127_3650036_11 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.000000000000000003286 90.0
TLS3_k127_3650036_12 redox protein, regulator of disulfide bond formation - - - 0.00007398 52.0
TLS3_k127_3650036_2 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008341 367.0
TLS3_k127_3650036_3 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.0000000000000000000000000000000000000000000000000000784 196.0
TLS3_k127_3650036_4 Response regulator receiver - - - 0.00000000000000000000000000000451 138.0
TLS3_k127_3650036_5 Transcriptional regulator - - - 0.00000000000000000000000000001263 122.0
TLS3_k127_3650036_6 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000123 120.0
TLS3_k127_3650036_7 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000728 119.0
TLS3_k127_3650036_8 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.000000000000000000001424 102.0
TLS3_k127_3650036_9 - - - - 0.000000000000000000001587 96.0
TLS3_k127_3686982_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1035.0
TLS3_k127_3686982_1 elongation factor G domain IV K02355 - - 3.483e-235 751.0
TLS3_k127_3686982_10 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000007009 188.0
TLS3_k127_3686982_11 CcmB protein K02193,K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.000000000000000000000000000000000000000000000008803 184.0
TLS3_k127_3686982_12 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000076 179.0
TLS3_k127_3686982_13 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000001256 161.0
TLS3_k127_3686982_14 ABC transporter K02193 - 3.6.3.41 0.000000000000000000000000000000000000001798 156.0
TLS3_k127_3686982_15 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000004486 139.0
TLS3_k127_3686982_16 Conserved TM helix - - - 0.0000000000000000000000000000007364 131.0
TLS3_k127_3686982_17 subunit of a heme lyase K02198,K02200 - - 0.0000000000000000000000002 122.0
TLS3_k127_3686982_18 - - - - 0.00000000000001006 76.0
TLS3_k127_3686982_19 metal-dependent hydrolase of the TIM-barrel fold - - - 0.00000000000005592 83.0
TLS3_k127_3686982_2 PFAM Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 552.0
TLS3_k127_3686982_20 cytochrome complex assembly K02198,K02200 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 - 0.00000000001112 78.0
TLS3_k127_3686982_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 393.0
TLS3_k127_3686982_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 343.0
TLS3_k127_3686982_5 Belongs to the NadC ModD family K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 293.0
TLS3_k127_3686982_6 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008273 269.0
TLS3_k127_3686982_7 HTH domain K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000002865 235.0
TLS3_k127_3686982_8 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000003426 195.0
TLS3_k127_3686982_9 Thioredoxin-like K02199,K03671 - - 0.0000000000000000000000000000000000000000000000001764 183.0
TLS3_k127_371500_0 GAD domain K01876 - 6.1.1.12 6.985e-232 731.0
TLS3_k127_371500_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.056e-197 627.0
TLS3_k127_371500_10 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 386.0
TLS3_k127_371500_11 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 374.0
TLS3_k127_371500_12 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 377.0
TLS3_k127_371500_13 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 350.0
TLS3_k127_371500_14 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 336.0
TLS3_k127_371500_15 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 328.0
TLS3_k127_371500_16 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 331.0
TLS3_k127_371500_17 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 301.0
TLS3_k127_371500_18 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 286.0
TLS3_k127_371500_19 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003355 283.0
TLS3_k127_371500_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 572.0
TLS3_k127_371500_20 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002993 283.0
TLS3_k127_371500_21 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007253 268.0
TLS3_k127_371500_22 Glycosyl transferase, family 9 K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005057 256.0
TLS3_k127_371500_23 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000002502 241.0
TLS3_k127_371500_24 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000005911 228.0
TLS3_k127_371500_25 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000003263 222.0
TLS3_k127_371500_26 dTDP-4-dehydrorhamnose reductase K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000006733 218.0
TLS3_k127_371500_27 FeS assembly SUF system protein SufT - - - 0.0000000000000000000000000000000000000000000000000001242 192.0
TLS3_k127_371500_28 SUF system FeS assembly protein K04488 - - 0.00000000000000000000000000000000000000000000000001915 184.0
TLS3_k127_371500_29 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000003708 192.0
TLS3_k127_371500_3 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 569.0
TLS3_k127_371500_30 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 0.000000000000000000000000000000000000000000001154 179.0
TLS3_k127_371500_31 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000251 168.0
TLS3_k127_371500_32 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000001057 173.0
TLS3_k127_371500_33 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000002259 160.0
TLS3_k127_371500_34 Pfam:DUF59 K02612 - - 0.00000000000000000000000000000000000000725 149.0
TLS3_k127_371500_35 COG2346, Truncated hemoglobins K06886 - - 0.0000000000000000000000000000003237 128.0
TLS3_k127_371500_36 - - - - 0.000000000000000000000000007679 122.0
TLS3_k127_371500_37 Outer membrane protein (OmpH-like) K06142 - - 0.0000000000000000000000001229 112.0
TLS3_k127_371500_38 Belongs to the UPF0434 family K09791 - - 0.0000000000000000000004012 96.0
TLS3_k127_371500_39 kinase activity - - - 0.000000000000000000002112 105.0
TLS3_k127_371500_4 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 558.0
TLS3_k127_371500_40 - - - - 0.0000000000000000001196 98.0
TLS3_k127_371500_41 Transcriptional regulator - - - 0.000000000000000004882 90.0
TLS3_k127_371500_42 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000001516 59.0
TLS3_k127_371500_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 518.0
TLS3_k127_371500_6 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 462.0
TLS3_k127_371500_7 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 431.0
TLS3_k127_371500_8 ABC transporter K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 406.0
TLS3_k127_371500_9 FeS assembly protein SufD K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 391.0
TLS3_k127_3737371_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1350.0
TLS3_k127_3737371_1 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000000000000000000002273 232.0
TLS3_k127_3737371_2 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.00000000000000000000000000000000000000000000000000000000004155 222.0
TLS3_k127_3737371_3 CBS domain K04767,K07168,K07182 - - 0.000000000000000000000008783 108.0
TLS3_k127_3737371_4 PFAM CBS domain containing protein K04767 - - 0.000000000000000000001445 99.0
TLS3_k127_37609_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 319.0
TLS3_k127_37609_1 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000001122 217.0
TLS3_k127_37609_10 carbon monoxide dehydrogenase K09386 - - 0.000000004088 63.0
TLS3_k127_37609_2 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000002048 210.0
TLS3_k127_37609_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000001124 175.0
TLS3_k127_37609_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.0000000000000000000000000000000003199 139.0
TLS3_k127_37609_5 sulfopyruvate decarboxylase, alpha subunit K06034 - 4.1.1.79 0.00000000000000000000000000007671 122.0
TLS3_k127_37609_6 Belongs to the GST superfamily K03599 - - 0.0000000000000000000000000009631 123.0
TLS3_k127_37609_7 endoribonuclease L-PSP - - - 0.00000000000000000000000001147 113.0
TLS3_k127_37609_8 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000006889 81.0
TLS3_k127_37609_9 Redoxin K03564 - 1.11.1.15 0.000000002785 61.0
TLS3_k127_3770365_0 PFAM FAD dependent oxidoreductase K15736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 479.0
TLS3_k127_3770365_1 Luciferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 432.0
TLS3_k127_3770365_10 Amidohydrolase K14333 - 4.1.1.46 0.00000000000000000000000002696 121.0
TLS3_k127_3770365_11 Protein of unknown function (DUF721) - - - 0.000000000000000005225 90.0
TLS3_k127_3770365_2 Methionyl-tRNA formyltransferase K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 345.0
TLS3_k127_3770365_3 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 297.0
TLS3_k127_3770365_4 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003498 283.0
TLS3_k127_3770365_5 Ornithine cyclodeaminase K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000003114 244.0
TLS3_k127_3770365_6 Methyltransferase small domain protein - - - 0.000000000000000000000000000000000000000000000000000000003637 209.0
TLS3_k127_3770365_7 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000002206 192.0
TLS3_k127_3770365_8 intermembrane phospholipid transfer K07323 - - 0.000000000000000000000000000000000000000000000000003542 188.0
TLS3_k127_3770365_9 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000006127 164.0
TLS3_k127_3817018_0 Sulfate permease family K03321 - - 2.107e-232 732.0
TLS3_k127_3817018_1 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 580.0
TLS3_k127_3817018_2 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 340.0
TLS3_k127_3817018_3 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000001214 170.0
TLS3_k127_3817018_4 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000001408 162.0
TLS3_k127_3817018_5 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000005148 145.0
TLS3_k127_3817018_6 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000006701 106.0
TLS3_k127_384500_0 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 492.0
TLS3_k127_384500_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.0002251 51.0
TLS3_k127_3886002_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 2.929e-199 644.0
TLS3_k127_3886002_1 Belongs to the thiolase family K00626,K02615 - 2.3.1.174,2.3.1.223,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 527.0
TLS3_k127_3886002_10 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 314.0
TLS3_k127_3886002_11 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 285.0
TLS3_k127_3886002_12 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002509 284.0
TLS3_k127_3886002_13 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004658 272.0
TLS3_k127_3886002_14 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000001616 253.0
TLS3_k127_3886002_15 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000003492 211.0
TLS3_k127_3886002_16 PFAM type II secretion system protein G K02456 - - 0.0000000000000000000000000000000000000000000000006257 178.0
TLS3_k127_3886002_17 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000000000000000000000000204 183.0
TLS3_k127_3886002_18 PFAM Type II secretion system protein E K02454 - - 0.000000000000000000000000000000000000000000001217 169.0
TLS3_k127_3886002_19 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000006189 175.0
TLS3_k127_3886002_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 442.0
TLS3_k127_3886002_20 Pyridoxamine 5'-phosphate oxidase K09979 - - 0.00000000000000000000000000000000001406 142.0
TLS3_k127_3886002_21 Bacterial regulatory proteins, tetR family K09017 - - 0.00000000000000000000000000000000001573 144.0
TLS3_k127_3886002_22 Fimbrial assembly protein (PilN) K02461 - - 0.0000000000000000000000000000002456 140.0
TLS3_k127_3886002_23 molybdopterin cofactor binding K07402 - - 0.0000000000000000000000000001321 120.0
TLS3_k127_3886002_24 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000002126 88.0
TLS3_k127_3886002_25 Domain of unknown function DUF120 K07732 - 2.7.1.161 0.0000000000007132 74.0
TLS3_k127_3886002_26 type IV pilus modification protein PilV K02458 - - 0.0000000002953 68.0
TLS3_k127_3886002_27 - - - - 0.000000003043 64.0
TLS3_k127_3886002_28 General secretion pathway protein M K02462 - - 0.0000001128 61.0
TLS3_k127_3886002_29 Type II secretion system (T2SS), protein J K02459 - - 0.00000289 57.0
TLS3_k127_3886002_3 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 364.0
TLS3_k127_3886002_30 Domain of Unknown Function (DUF748) - - - 0.00000499 60.0
TLS3_k127_3886002_4 FMN-dependent dehydrogenase K01823 GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 358.0
TLS3_k127_3886002_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 343.0
TLS3_k127_3886002_6 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 334.0
TLS3_k127_3886002_7 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074,K01782 - 1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 310.0
TLS3_k127_3886002_8 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 294.0
TLS3_k127_3886002_9 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 296.0
TLS3_k127_3915402_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000002289 222.0
TLS3_k127_3915402_1 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000008468 176.0
TLS3_k127_3915402_2 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides K01465 - 3.5.2.3 0.000005825 50.0
TLS3_k127_392748_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - - 0.0000000000000000000000000000000000000000000000000000000000000000342 229.0
TLS3_k127_392748_1 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.00000000000000000000000000000000003391 137.0
TLS3_k127_392748_2 4Fe-4S single cluster domain K05337 - - 0.00000002837 57.0
TLS3_k127_3992997_0 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 318.0
TLS3_k127_3992997_1 Cyclodeaminase K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000001102 267.0
TLS3_k127_3992997_2 methyltransferase activity - - - 0.0000000000000000000000000000000000000000001563 163.0
TLS3_k127_3992997_3 Amidohydrolase - - - 0.00000000000000000000000000000000000004387 149.0
TLS3_k127_3992997_4 - - - - 0.000000000000000000000001988 106.0
TLS3_k127_3992997_5 Amidohydrolase K10221 - 3.1.1.57 0.0000000000000000000000163 105.0
TLS3_k127_3992997_6 NMT1-like family K02051 - - 0.000000000000000003111 97.0
TLS3_k127_3992997_7 NMT1-like family K02051 - - 0.00000000000000004481 93.0
TLS3_k127_3992997_8 Amidohydrolase K07045 - - 0.000000000001523 69.0
TLS3_k127_3995966_0 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000007323 183.0
TLS3_k127_3995966_1 iron ion homeostasis K02012 - - 0.00000000000001196 85.0
TLS3_k127_4017758_0 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 310.0
TLS3_k127_4017758_1 UPF0391 membrane protein - - - 0.0000000000000005767 78.0
TLS3_k127_4017758_2 Histidine kinase A domain protein - - - 0.000000000000002221 85.0
TLS3_k127_4017758_3 Protein of unknown function (DUF3096) - - - 0.000000001428 59.0
TLS3_k127_4017758_4 hyperosmotic response K04065 - - 0.00000001126 64.0
TLS3_k127_4046534_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.0 1242.0
TLS3_k127_4046534_1 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 1.068e-234 736.0
TLS3_k127_4046534_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000004572 191.0
TLS3_k127_4046534_11 Biotin-requiring enzyme - - - 0.00000000000000000000000000000000005287 139.0
TLS3_k127_4046534_12 mttA/Hcf106 family K03116,K03117 - - 0.00000000000000007545 85.0
TLS3_k127_4046534_13 DTW - - - 0.0005763 44.0
TLS3_k127_4046534_2 Biotin carboxylase K01961,K01965 - 6.3.4.14,6.4.1.2,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 578.0
TLS3_k127_4046534_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 557.0
TLS3_k127_4046534_4 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 407.0
TLS3_k127_4046534_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000999 375.0
TLS3_k127_4046534_6 Metallopeptidase family M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 366.0
TLS3_k127_4046534_7 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 339.0
TLS3_k127_4046534_8 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000003248 264.0
TLS3_k127_4046534_9 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000001203 232.0
TLS3_k127_4071944_0 Alpha-amylase domain K01182,K01187,K01226 - 3.2.1.10,3.2.1.20,3.2.1.93 1.307e-216 684.0
TLS3_k127_4071944_1 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 464.0
TLS3_k127_4071944_2 PFAM Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000169 271.0
TLS3_k127_4071944_3 - - - - 0.00000000000000000000000000000000000000000003476 166.0
TLS3_k127_4071944_4 Thiamine-binding protein - - - 0.0000000000000000004607 91.0
TLS3_k127_4071944_5 two component, sigma54 specific, transcriptional regulator, Fis family K10943 - - 0.0000000000000000142 85.0
TLS3_k127_4071944_6 - - - - 0.000000000000004878 79.0
TLS3_k127_4071944_7 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.00000001305 59.0
TLS3_k127_4071944_8 - - - - 0.0001013 51.0
TLS3_k127_4080063_0 Protein of unknown function (DUF3750) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 297.0
TLS3_k127_4080063_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000004404 188.0
TLS3_k127_4080063_2 - - - - 0.0003415 46.0
TLS3_k127_4080350_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 505.0
TLS3_k127_4080350_1 arginyltransferase activity K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000001878 226.0
TLS3_k127_4080350_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000008047 68.0
TLS3_k127_4158703_0 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008687 507.0
TLS3_k127_4158703_1 PFAM helix-turn-helix, AraC type ThiJ PfpI - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 406.0
TLS3_k127_4158703_2 protein conserved in bacteria - - - 0.0000000000000000000000000007144 126.0
TLS3_k127_4158703_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000001357 94.0
TLS3_k127_4244322_0 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 364.0
TLS3_k127_4244322_1 quinone binding K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003644 285.0
TLS3_k127_4244322_2 Domain of unknown function (DUF4149) - - - 0.00000000000000000000000000000000000000001928 160.0
TLS3_k127_4244322_3 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000001204 151.0
TLS3_k127_4244322_4 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000000000000000000000000003534 126.0
TLS3_k127_4244322_5 Polysaccharide deacetylase K00365,K01452 GO:0000003,GO:0000272,GO:0003006,GO:0005575,GO:0005618,GO:0005619,GO:0005623,GO:0005631,GO:0005975,GO:0005976,GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006037,GO:0006039,GO:0006040,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009272,GO:0009277,GO:0009653,GO:0009987,GO:0010383,GO:0010927,GO:0016043,GO:0016052,GO:0016998,GO:0017144,GO:0019953,GO:0022402,GO:0022411,GO:0022413,GO:0022414,GO:0022607,GO:0030154,GO:0030312,GO:0030435,GO:0030437,GO:0030476,GO:0031160,GO:0031505,GO:0032502,GO:0032505,GO:0032989,GO:0034218,GO:0034232,GO:0034293,GO:0042244,GO:0042546,GO:0042737,GO:0043170,GO:0043934,GO:0043935,GO:0044036,GO:0044085,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044277,GO:0044426,GO:0044462,GO:0044464,GO:0044703,GO:0045229,GO:0046348,GO:0048468,GO:0048646,GO:0048856,GO:0048869,GO:0051321,GO:0051704,GO:0070590,GO:0070591,GO:0070726,GO:0070910,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071852,GO:0071853,GO:0071854,GO:0071940,GO:0071944,GO:0071966,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903046 1.7.3.3,3.5.1.41 0.0000009189 52.0
TLS3_k127_4245143_0 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000008072 200.0
TLS3_k127_4245143_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000008649 187.0
TLS3_k127_4245143_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000009382 179.0
TLS3_k127_4245143_3 protein conserved in bacteria - - - 0.000000000000000003556 88.0
TLS3_k127_4245143_4 Tripartite tricarboxylate transporter TctA family - - - 0.0000000001647 70.0
TLS3_k127_4261297_0 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 542.0
TLS3_k127_4261297_1 Aromatic amino acid lyase K01745,K10774 GO:0003674,GO:0003824,GO:0016829,GO:0016840,GO:0016841,GO:0016853,GO:0016866,GO:0016869,GO:0050368 4.3.1.23,4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 517.0
TLS3_k127_4261297_2 Bacterial lipid A biosynthesis acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 412.0
TLS3_k127_4261297_3 glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 318.0
TLS3_k127_4261297_4 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 312.0
TLS3_k127_4261297_5 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000003227 216.0
TLS3_k127_4261297_6 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000000000000008518 132.0
TLS3_k127_4261297_7 acyl carrier protein K02078 - - 0.0000000000000000000000000000001938 125.0
TLS3_k127_4261297_8 Beta-ketoacyl synthase, N-terminal domain - - - 0.0000000000000000000000000000458 126.0
TLS3_k127_4268136_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 3.804e-266 837.0
TLS3_k127_4268136_1 PFAM peptidase M16 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 394.0
TLS3_k127_4268136_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000007332 173.0
TLS3_k127_4268136_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000004442 146.0
TLS3_k127_4268136_4 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000004646 134.0
TLS3_k127_4344829_0 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000006992 163.0
TLS3_k127_4344829_2 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.00000000001873 69.0
TLS3_k127_4344829_3 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.00000000001892 65.0
TLS3_k127_4388_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1208.0
TLS3_k127_4388_1 aspartic-type endopeptidase activity K06985 - - 0.0000000000000000000000722 106.0
TLS3_k127_4390034_0 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 313.0
TLS3_k127_4390034_1 Psort location CytoplasmicMembrane, score 9.46 - - - 0.00000000000000000002708 96.0
TLS3_k127_4435182_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 8.665e-274 860.0
TLS3_k127_4435182_1 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 517.0
TLS3_k127_4435182_10 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000002485 167.0
TLS3_k127_4435182_11 stress-induced protein - - - 0.00000000000000000000000000000000000000163 162.0
TLS3_k127_4435182_12 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000003813 140.0
TLS3_k127_4435182_13 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.000000000000000000000001125 108.0
TLS3_k127_4435182_14 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000002933 82.0
TLS3_k127_4435182_15 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.000000000000002943 80.0
TLS3_k127_4435182_17 Alpha beta hydrolase - - - 0.000000000001156 71.0
TLS3_k127_4435182_2 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 437.0
TLS3_k127_4435182_3 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 400.0
TLS3_k127_4435182_4 ADP-L-glycero-beta-D-manno-heptose biosynthetic process K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000002077 264.0
TLS3_k127_4435182_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000001657 230.0
TLS3_k127_4435182_6 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000005145 226.0
TLS3_k127_4435182_7 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000002808 205.0
TLS3_k127_4435182_8 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000002459 185.0
TLS3_k127_4435182_9 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000006911 168.0
TLS3_k127_4447232_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 621.0
TLS3_k127_4447232_1 CHAT domain K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 590.0
TLS3_k127_4447232_2 lipid kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000001064 218.0
TLS3_k127_4447232_3 F420H(2)-dependent quinone reductase - - - 0.0000004232 51.0
TLS3_k127_4469107_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520,K21739 - 1.16.1.1 1.396e-213 672.0
TLS3_k127_4469107_1 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 458.0
TLS3_k127_4469107_10 Catalyzes the conversion of maleate to fumarate K01799 - 5.2.1.1 0.000000001342 68.0
TLS3_k127_4469107_11 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0001282 46.0
TLS3_k127_4469107_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 299.0
TLS3_k127_4469107_3 Amidinotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 288.0
TLS3_k127_4469107_4 DnaJ molecular chaperone homology domain K03686 - - 0.000000000000000000000000000000000008729 145.0
TLS3_k127_4469107_5 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000001923 118.0
TLS3_k127_4469107_6 amidohydrolase K07045 - - 0.0000000000000003054 89.0
TLS3_k127_4469107_7 von Willebrand factor (vWF) type A domain - - - 0.0000000000003391 70.0
TLS3_k127_4469107_8 Cupin domain - - - 0.000000000001505 67.0
TLS3_k127_4469107_9 Efflux pump membrane transporter K18138 - - 0.000000000002695 69.0
TLS3_k127_4500174_0 ornithine cyclodeaminase K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000002069 237.0
TLS3_k127_4500174_1 PFAM amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000009183 201.0
TLS3_k127_4500174_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000005627 72.0
TLS3_k127_4521198_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 329.0
TLS3_k127_4521198_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000005801 242.0
TLS3_k127_4521198_2 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000831 220.0
TLS3_k127_4521198_3 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000001735 170.0
TLS3_k127_4521198_4 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0000000000002089 80.0
TLS3_k127_4521198_6 - - - - 0.000000001932 63.0
TLS3_k127_4521198_7 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000004946 55.0
TLS3_k127_4521198_8 Outer membrane lipoprotein - - - 0.0000004996 60.0
TLS3_k127_4544504_0 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 344.0
TLS3_k127_4544504_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 333.0
TLS3_k127_4544504_2 - - - - 0.000000000000000000000000000000000000000000000000000000000005871 212.0
TLS3_k127_4544504_3 RNA recognition motif - - - 0.0000000000000000000000000000000000000008973 152.0
TLS3_k127_4544504_4 iron dependent repressor K01356,K03709 - 3.4.21.88 0.000000000000000000000000006658 111.0
TLS3_k127_4544504_5 AhpC/TSA antioxidant enzyme - - - 0.0000000000000000003168 92.0
TLS3_k127_4544771_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.309e-249 790.0
TLS3_k127_4544771_1 Cytokinin riboside 5'-monophosphate phosphoribohydrolase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 309.0
TLS3_k127_4544771_2 CHRD domain - - - 0.000000000000000000000000000000000001439 147.0
TLS3_k127_4544771_3 PFAM Conserved nitrate reductase-associated protein (Nitr_red_assoc) - - - 0.0000000000000001263 86.0
TLS3_k127_4549438_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 591.0
TLS3_k127_4549438_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 525.0
TLS3_k127_4549438_10 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000002769 206.0
TLS3_k127_4549438_11 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000004205 185.0
TLS3_k127_4549438_12 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000006759 166.0
TLS3_k127_4549438_13 Membrane K08988 - - 0.00000000000000000000000000000000000000000004952 170.0
TLS3_k127_4549438_14 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000249 157.0
TLS3_k127_4549438_15 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000002015 139.0
TLS3_k127_4549438_16 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000005084 135.0
TLS3_k127_4549438_17 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000002253 139.0
TLS3_k127_4549438_18 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000001033 133.0
TLS3_k127_4549438_19 SMART HNH nuclease K07451 - - 0.00000000000000000000000000000001949 128.0
TLS3_k127_4549438_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 401.0
TLS3_k127_4549438_20 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000007318 118.0
TLS3_k127_4549438_21 Transcription factor zinc-finger K09981 - - 0.00000000000008173 79.0
TLS3_k127_4549438_22 haloacid dehalogenase-like hydrolase - - - 0.00001788 55.0
TLS3_k127_4549438_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 390.0
TLS3_k127_4549438_4 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 394.0
TLS3_k127_4549438_5 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009475 370.0
TLS3_k127_4549438_6 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001393 263.0
TLS3_k127_4549438_7 PFAM LemA family protein K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000004331 239.0
TLS3_k127_4549438_8 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000002135 214.0
TLS3_k127_4549438_9 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000000000000000000000001003 207.0
TLS3_k127_4563806_0 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 306.0
TLS3_k127_4563806_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000002002 213.0
TLS3_k127_4563806_2 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000318 136.0
TLS3_k127_4563806_3 ABC-type nitrate sulfonate bicarbonate transport - - - 0.0000000000000000000000000005706 124.0
TLS3_k127_4590333_0 nuclear-transcribed mRNA catabolic process, no-go decay - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 496.0
TLS3_k127_4590333_1 Conserved carboxylase domain K01571 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 388.0
TLS3_k127_4590333_10 ribosomal subunit interface protein - - - 0.000000000000000000000000000002153 123.0
TLS3_k127_4590333_11 Glcg protein - - - 0.00000000000000000000004894 103.0
TLS3_k127_4590333_12 bleomycin resistance protein - - - 0.00000006159 60.0
TLS3_k127_4590333_13 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000001892 62.0
TLS3_k127_4590333_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00001941 55.0
TLS3_k127_4590333_2 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 303.0
TLS3_k127_4590333_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007959 290.0
TLS3_k127_4590333_4 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002821 255.0
TLS3_k127_4590333_5 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000009948 224.0
TLS3_k127_4590333_6 major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000002419 214.0
TLS3_k127_4590333_7 ribonucleoside-diphosphate reductase activity K07735 - - 0.000000000000000000000000000000000000000000000000181 183.0
TLS3_k127_4590333_8 Peptidase S16, lon domain protein K07157 - - 0.0000000000000000000000000000000000000000001771 168.0
TLS3_k127_4590333_9 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000004763 154.0
TLS3_k127_4623745_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 374.0
TLS3_k127_4623745_1 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 297.0
TLS3_k127_4623745_2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000007427 146.0
TLS3_k127_4623745_3 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000007264 137.0
TLS3_k127_4641436_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 8.339e-267 832.0
TLS3_k127_4641436_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 4.358e-258 824.0
TLS3_k127_4641436_10 PFAM Nitrile hydratase alpha K01721 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000001904 267.0
TLS3_k127_4641436_11 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000001643 214.0
TLS3_k127_4641436_12 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000002728 203.0
TLS3_k127_4641436_13 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000005292 207.0
TLS3_k127_4641436_14 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000003682 177.0
TLS3_k127_4641436_15 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000006062 177.0
TLS3_k127_4641436_16 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.0000000000000000000000000000000000000002211 155.0
TLS3_k127_4641436_17 TIR domain - - - 0.000000000000000000000000000000000001392 145.0
TLS3_k127_4641436_18 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000003898 140.0
TLS3_k127_4641436_19 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K02439,K07390 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016740,GO:0016782,GO:0016783,GO:0044424,GO:0044464 2.8.1.1 0.00000000000000000000000000000009998 126.0
TLS3_k127_4641436_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006828 556.0
TLS3_k127_4641436_20 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.000000000000000000000000000001967 123.0
TLS3_k127_4641436_21 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.00000000000000000000002089 102.0
TLS3_k127_4641436_22 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000001305 101.0
TLS3_k127_4641436_23 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.00000000000000000009757 96.0
TLS3_k127_4641436_24 Protein of unknown function (DUF503) K09764 - - 0.000000000000000006258 87.0
TLS3_k127_4641436_25 major facilitator superfamily K08161 - - 0.0000000002018 72.0
TLS3_k127_4641436_26 TPM domain K06872 - - 0.0000000003467 70.0
TLS3_k127_4641436_27 Belongs to the peptidase S41A family K03797 GO:0003674,GO:0003824,GO:0004175,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009653,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030154,GO:0030288,GO:0030313,GO:0030435,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043603,GO:0043900,GO:0043902,GO:0043934,GO:0044237,GO:0044238,GO:0044464,GO:0046983,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1900190,GO:1900192,GO:1901564 3.4.21.102 0.0000001733 59.0
TLS3_k127_4641436_28 Protein of unknown function (DUF448) K07742 - - 0.0000006275 54.0
TLS3_k127_4641436_3 response regulator K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 507.0
TLS3_k127_4641436_4 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 456.0
TLS3_k127_4641436_5 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 368.0
TLS3_k127_4641436_6 Glucose dehydrogenase C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 364.0
TLS3_k127_4641436_7 FMN-dependent dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 359.0
TLS3_k127_4641436_8 Domain of unknown function (DUF427) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 317.0
TLS3_k127_4641436_9 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 304.0
TLS3_k127_4673999_0 PFAM Integrase, catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 555.0
TLS3_k127_4673999_1 PFAM IstB domain protein ATP-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001164 255.0
TLS3_k127_4673999_2 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K05921 - 4.1.1.68 0.00000000000000000000000000000000000000000000000000000000000000000003822 242.0
TLS3_k127_4697693_0 DNA photolyase activity K03716 - 4.1.99.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 358.0
TLS3_k127_4697693_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 308.0
TLS3_k127_4697693_2 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 291.0
TLS3_k127_4697693_3 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000443 239.0
TLS3_k127_4697693_4 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000000000000002872 211.0
TLS3_k127_4697693_5 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000000000000000000000000000000000002675 156.0
TLS3_k127_4697693_6 Diguanylate cyclase - - - 0.0000000000001941 79.0
TLS3_k127_4697693_7 ParB domain protein nuclease K03497 - - 0.0009785 50.0
TLS3_k127_4709488_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1033.0
TLS3_k127_4709488_1 UDP binding domain K02474,K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 486.0
TLS3_k127_4714386_0 Bacterial transferase hexapeptide (six repeats) K02617,K08279 - - 0.0000000000000000000000000000000000000000000000000005034 198.0
TLS3_k127_4714386_1 RNA recognition motif - - - 0.00000000000000000000000000000000001372 139.0
TLS3_k127_4714386_2 CarD-like/TRCF domain K07736 - - 0.0000000005164 68.0
TLS3_k127_4722632_0 Domain of unknown function (DUF892) - - - 0.0000000000000000000000000000000000000000000000000000000000004773 214.0
TLS3_k127_4722632_1 - - - - 0.000000001079 63.0
TLS3_k127_479361_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 396.0
TLS3_k127_479361_1 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 300.0
TLS3_k127_479361_10 peptidoglycan-binding domain-containing protein - - - 0.00000000000002355 84.0
TLS3_k127_479361_12 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000003214 61.0
TLS3_k127_479361_13 AAA domain (dynein-related subfamily) K07452 - - 0.000000005066 61.0
TLS3_k127_479361_14 hyperosmotic response K04065 - - 0.000000007705 61.0
TLS3_k127_479361_15 Glycine zipper - - - 0.0002383 48.0
TLS3_k127_479361_2 SNARE associated Golgi protein K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002419 268.0
TLS3_k127_479361_3 Mrr N-terminal domain K07448 - - 0.0000000000000000000000000000000000000000000000000000000000001088 218.0
TLS3_k127_479361_4 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000003436 217.0
TLS3_k127_479361_5 Domain of unknown function (DUF1971) - - - 0.000000000000000000000000000000000000000000000000000001969 195.0
TLS3_k127_479361_6 COG0563 Adenylate kinase and related kinases - - - 0.000000000000000000000000000000000000000000000001029 180.0
TLS3_k127_479361_7 major facilitator superfamily - - - 0.00000000000000000000000000000000000003105 158.0
TLS3_k127_479361_8 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000002064 109.0
TLS3_k127_479361_9 restriction endonuclease K07448 - - 0.0000000000000003363 80.0
TLS3_k127_4799933_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1067.0
TLS3_k127_4799933_1 Belongs to the ClpA ClpB family K03694 - - 2.951e-295 923.0
TLS3_k127_4799933_10 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 369.0
TLS3_k127_4799933_11 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 368.0
TLS3_k127_4799933_12 molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005885 355.0
TLS3_k127_4799933_13 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 354.0
TLS3_k127_4799933_14 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009611 340.0
TLS3_k127_4799933_15 Molybdenum Cofactor Synthesis C K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 336.0
TLS3_k127_4799933_16 Hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000036 276.0
TLS3_k127_4799933_17 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006103 254.0
TLS3_k127_4799933_18 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000000000003298 213.0
TLS3_k127_4799933_19 Isochorismatase family K09020 - 3.5.1.110 0.0000000000000000000000000000000000000000000000000000003001 200.0
TLS3_k127_4799933_2 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis - - - 1.013e-286 886.0
TLS3_k127_4799933_20 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000001559 198.0
TLS3_k127_4799933_21 Nitrogen regulatory protein P-II K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.000000000000000000000000000000000000000000000008068 176.0
TLS3_k127_4799933_22 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000004482 174.0
TLS3_k127_4799933_23 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000004765 164.0
TLS3_k127_4799933_24 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000006927 157.0
TLS3_k127_4799933_25 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000004346 136.0
TLS3_k127_4799933_26 Class ii aldolase K01628 - 4.1.2.17 0.00000000000000000000000000000005287 134.0
TLS3_k127_4799933_27 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000001996 134.0
TLS3_k127_4799933_28 plasmid maintenance K03496 - - 0.00000000000000000000000002377 111.0
TLS3_k127_4799933_29 membrane transporter protein K07090 - - 0.0000000000000000002798 97.0
TLS3_k127_4799933_3 Protein of unknown function, DUF255 K06888 - - 1.755e-220 704.0
TLS3_k127_4799933_30 PAS domain containing protein - - - 0.00000000000002858 83.0
TLS3_k127_4799933_31 'Cold-shock' DNA-binding domain K03704 - - 0.00000000004642 66.0
TLS3_k127_4799933_32 Belongs to the MT-A70-like family - - - 0.0000002214 61.0
TLS3_k127_4799933_33 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00001992 49.0
TLS3_k127_4799933_4 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 2.96e-220 691.0
TLS3_k127_4799933_5 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 586.0
TLS3_k127_4799933_6 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 569.0
TLS3_k127_4799933_7 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 483.0
TLS3_k127_4799933_8 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 431.0
TLS3_k127_4799933_9 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 406.0
TLS3_k127_4823739_0 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001449 254.0
TLS3_k127_4823739_1 BON domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003175 239.0
TLS3_k127_4823739_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000000000000001134 158.0
TLS3_k127_4823739_3 Pfam Tetratricopeptide - - - 0.000000000000000000000000000000004058 131.0
TLS3_k127_4823739_4 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000000000001437 125.0
TLS3_k127_4823739_5 COGs COG2905 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.000000000000000000001507 106.0
TLS3_k127_4823739_6 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000008659 66.0
TLS3_k127_4851829_0 PFAM Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 346.0
TLS3_k127_4851829_1 thiamine-containing compound biosynthetic process K04102 - 4.1.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 319.0
TLS3_k127_4851829_2 Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000005756 213.0
TLS3_k127_4851829_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000335 122.0
TLS3_k127_4851829_4 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.00000000004587 73.0
TLS3_k127_4851829_5 NMT1-like family - - - 0.00000000005601 73.0
TLS3_k127_485978_0 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 475.0
TLS3_k127_485978_1 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 350.0
TLS3_k127_485978_2 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 306.0
TLS3_k127_485978_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000002544 187.0
TLS3_k127_485978_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000004133 186.0
TLS3_k127_485978_5 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000006472 179.0
TLS3_k127_485978_6 RDD family - - - 0.0000000000000008024 86.0
TLS3_k127_485978_7 DNA integration - - - 0.000000000000002713 82.0
TLS3_k127_4870085_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.965e-246 775.0
TLS3_k127_4870085_1 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 404.0
TLS3_k127_4870085_2 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000001908 144.0
TLS3_k127_4870085_3 Class ii aldolase K01628 - 4.1.2.17 0.000000000000000000000000000001558 130.0
TLS3_k127_5026285_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 575.0
TLS3_k127_5026285_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 570.0
TLS3_k127_5026285_2 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 422.0
TLS3_k127_5026285_3 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 328.0
TLS3_k127_5026285_4 COG3842 ABC-type spermidine putrescine transport systems, ATPase components K02010,K02017,K15497 - 3.6.3.29,3.6.3.30,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 320.0
TLS3_k127_5026285_5 Amidohydrolase family K01464,K01465 - 3.5.2.2,3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 307.0
TLS3_k127_5026285_6 KR domain - - - 0.0000000000000000000000000000000000000000000005144 176.0
TLS3_k127_5026285_7 FCD - - - 0.000000000000000000000000000527 123.0
TLS3_k127_5075049_0 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 531.0
TLS3_k127_5075049_1 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 293.0
TLS3_k127_5075049_2 Protein of unknown function (DUF2945) - - - 0.00000000000000011 82.0
TLS3_k127_5077317_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 497.0
TLS3_k127_5077317_1 PFAM Acyl-CoA dehydrogenase K16173 - 1.3.99.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 398.0
TLS3_k127_5077317_2 Abc transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000009483 161.0
TLS3_k127_5077317_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000004927 49.0
TLS3_k127_5096781_0 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000003975 220.0
TLS3_k127_5096781_1 PFAM amidohydrolase K01464,K01465 - 3.5.2.2,3.5.2.3 0.000000000000000000000000000000000000000000000000000000001062 208.0
TLS3_k127_5186339_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 448.0
TLS3_k127_5186339_1 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 326.0
TLS3_k127_5186339_2 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000001745 175.0
TLS3_k127_5186339_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000007685 150.0
TLS3_k127_5186339_4 maleate cis-trans isomerase K01799 - 5.2.1.1 0.000000000000004402 85.0
TLS3_k127_5211555_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1086.0
TLS3_k127_5211555_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 7.093e-303 948.0
TLS3_k127_5211555_10 Jag_N K06346 - - 0.0000000000000000000000000000000000000006127 158.0
TLS3_k127_5211555_11 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000001578 105.0
TLS3_k127_5211555_12 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000008761 108.0
TLS3_k127_5211555_13 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000002301 86.0
TLS3_k127_5211555_14 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000003607 85.0
TLS3_k127_5211555_15 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000959 74.0
TLS3_k127_5211555_16 PFAM SMP-30 Gluconolaconase - - - 0.000007015 52.0
TLS3_k127_5211555_2 Aminoacyl-tRNA editing domain K01881 - 6.1.1.15 1.036e-229 724.0
TLS3_k127_5211555_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 539.0
TLS3_k127_5211555_4 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 367.0
TLS3_k127_5211555_5 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 341.0
TLS3_k127_5211555_6 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 313.0
TLS3_k127_5211555_7 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 289.0
TLS3_k127_5211555_8 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000001866 263.0
TLS3_k127_5211555_9 auxin efflux carrier K07088 - - 0.000000000000000000000000000000000000000000001031 176.0
TLS3_k127_5262658_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07713,K07714,K10943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009643 366.0
TLS3_k127_5262658_1 STAS domain K17763 - - 0.000000000000000005302 87.0
TLS3_k127_5262658_2 PAS domain K07710 - 2.7.13.3 0.00000000001201 76.0
TLS3_k127_5310509_0 Multidrug ABC transporter permease K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009099 396.0
TLS3_k127_5310509_1 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 371.0
TLS3_k127_5310509_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 346.0
TLS3_k127_5310509_3 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000649 324.0
TLS3_k127_5310509_4 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004275 271.0
TLS3_k127_5310509_5 Cupin 2, conserved barrel domain protein K11312 - - 0.000000000000001379 80.0
TLS3_k127_5310509_6 MarR family transcriptional regulator - - - 0.000000000000004927 75.0
TLS3_k127_5310509_8 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K15576 - - 0.00002116 50.0
TLS3_k127_5318778_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 441.0
TLS3_k127_5318778_1 nitrogen compound transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 355.0
TLS3_k127_5318778_2 RmlD substrate binding domain K01784,K02473,K03274,K08678 - 4.1.1.35,5.1.3.2,5.1.3.20,5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 344.0
TLS3_k127_5318778_3 Carbon-nitrogen hydrolase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 298.0
TLS3_k127_5318778_4 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003817 284.0
TLS3_k127_5318778_5 ornithine cyclodeaminase K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000005438 177.0
TLS3_k127_5318778_6 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000402 162.0
TLS3_k127_5318778_7 PFAM Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000002035 143.0
TLS3_k127_5321798_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 552.0
TLS3_k127_5321798_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 516.0
TLS3_k127_5321798_10 ThiS family K03636 - - 0.00000000000000000000000000000001559 128.0
TLS3_k127_5321798_11 methionine transport K02071 - - 0.0000000000000005123 80.0
TLS3_k127_5321798_12 - - - - 0.000000000005243 72.0
TLS3_k127_5321798_13 HEAT repeats - - - 0.000004834 56.0
TLS3_k127_5321798_14 Protein of unknown function (DUF3426) - - - 0.000005109 55.0
TLS3_k127_5321798_2 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 424.0
TLS3_k127_5321798_3 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008948 391.0
TLS3_k127_5321798_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01883,K12339 - 2.5.1.47,6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 377.0
TLS3_k127_5321798_5 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 366.0
TLS3_k127_5321798_6 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 350.0
TLS3_k127_5321798_7 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 294.0
TLS3_k127_5321798_8 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007929 279.0
TLS3_k127_5321798_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000002028 156.0
TLS3_k127_5341251_0 lipopolysaccharide transport K22110 - - 0.0 1351.0
TLS3_k127_5341251_2 COG0457 FOG TPR repeat - - - 0.000000000000000000000004797 107.0
TLS3_k127_5341251_3 Carbohydrate/starch-binding module (family 21) - - - 0.000000000000000000000057 107.0
TLS3_k127_5341251_4 Catalyzes the conversion of maleate to fumarate K01799 - 5.2.1.1 0.00000000000008355 81.0
TLS3_k127_5366887_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.126e-285 895.0
TLS3_k127_5366887_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 553.0
TLS3_k127_5366887_2 Hydantoinase B/oxoprolinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 395.0
TLS3_k127_5366887_3 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 390.0
TLS3_k127_5366887_4 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009501 372.0
TLS3_k127_5366887_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 299.0
TLS3_k127_5366887_6 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000002102 248.0
TLS3_k127_5366887_7 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000000001178 134.0
TLS3_k127_5366887_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000002709 104.0
TLS3_k127_53816_0 pyruvate dehydrogenase (acetyl-transferring) activity K00163 - 1.2.4.1 0.0 1157.0
TLS3_k127_53816_1 PFAM PrkA AAA K07180 - - 0.0 1015.0
TLS3_k127_53816_10 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 344.0
TLS3_k127_53816_11 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 343.0
TLS3_k127_53816_12 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 323.0
TLS3_k127_53816_13 Cupin domain K00450 - 1.13.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 321.0
TLS3_k127_53816_14 PFAM ABC transporter related K01990,K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007625 317.0
TLS3_k127_53816_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 297.0
TLS3_k127_53816_16 Pfam Cupin K00450,K11948 - 1.13.11.38,1.13.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003826 284.0
TLS3_k127_53816_17 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000366 280.0
TLS3_k127_53816_18 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002163 274.0
TLS3_k127_53816_19 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000005395 254.0
TLS3_k127_53816_2 SpoVR family K06415 - - 2.512e-203 643.0
TLS3_k127_53816_20 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000001246 225.0
TLS3_k127_53816_21 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000793 228.0
TLS3_k127_53816_22 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000003563 214.0
TLS3_k127_53816_23 Glutathione S-transferase, C-terminal domain K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.0000000000000000000000000000000000000000000000000000000006404 209.0
TLS3_k127_53816_24 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000003402 192.0
TLS3_k127_53816_25 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000002747 177.0
TLS3_k127_53816_26 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000009902 177.0
TLS3_k127_53816_27 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000003455 177.0
TLS3_k127_53816_28 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000001745 183.0
TLS3_k127_53816_29 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000001235 167.0
TLS3_k127_53816_3 Belongs to the UPF0229 family K09786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 508.0
TLS3_k127_53816_30 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000000000000000000007143 146.0
TLS3_k127_53816_31 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000002386 145.0
TLS3_k127_53816_32 Glutathione S-transferase K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.000000000000000000000000000008132 120.0
TLS3_k127_53816_33 Transcription termination factor nusG - - - 0.000000000000000000000002146 109.0
TLS3_k127_53816_34 Glutathione S-transferase K07393 - 1.8.5.7 0.000000000000000000000284 102.0
TLS3_k127_53816_35 uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center - GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0071704,GO:1901575 - 0.000000000006056 74.0
TLS3_k127_53816_36 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.00000000005976 74.0
TLS3_k127_53816_37 2 iron, 2 sulfur cluster binding K00303 - 1.5.3.1 0.0000001239 57.0
TLS3_k127_53816_38 cysteine dioxygenase type I - - - 0.000001244 59.0
TLS3_k127_53816_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 485.0
TLS3_k127_53816_5 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 479.0
TLS3_k127_53816_6 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 441.0
TLS3_k127_53816_7 K -dependent Na Ca exchanger K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 409.0
TLS3_k127_53816_8 Peptidase family M28 K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 357.0
TLS3_k127_53816_9 LysR substrate binding domain K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 353.0
TLS3_k127_5382286_0 PFAM ATP-binding region ATPase domain protein K07709 - 2.7.13.3 0.0000000000000000000000000000002544 132.0
TLS3_k127_5382286_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000002184 107.0
TLS3_k127_5382286_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000005874 96.0
TLS3_k127_5382286_3 DnaK suppressor protein - - - 0.00000362 54.0
TLS3_k127_5384216_0 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 419.0
TLS3_k127_5384216_1 acetylesterase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 336.0
TLS3_k127_5411919_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 1.31e-213 686.0
TLS3_k127_5411919_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 3.559e-209 663.0
TLS3_k127_5411919_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 455.0
TLS3_k127_5411919_3 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000005294 178.0
TLS3_k127_5411919_4 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000008798 151.0
TLS3_k127_5411919_5 PFAM zinc finger, DksA TraR C4-type K06204 - - 0.0000000000000000000000000003838 119.0
TLS3_k127_5411919_6 Signal transduction histidine kinase K07777 - 2.7.13.3 0.00000000000000000000324 107.0
TLS3_k127_5411919_7 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000003604 99.0
TLS3_k127_5445208_0 involved in lipopolysaccharide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 436.0
TLS3_k127_5445208_1 Type II IV secretion system protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008307 405.0
TLS3_k127_5445208_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 372.0
TLS3_k127_5445208_3 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000001278 146.0
TLS3_k127_5445208_4 Lipid A core - O-antigen ligase and K02847 - - 0.000000000000000000000001277 118.0
TLS3_k127_5445208_5 Glycosyl transferase family group 2 K07011 - - 0.00000000000000000000006694 104.0
TLS3_k127_544871_0 PFAM amidohydrolase K07045 - - 0.0000000000000000000295 103.0
TLS3_k127_544871_1 NMT1-like family - - - 0.000000000000000001578 96.0
TLS3_k127_544871_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K16874 - - 0.0000000000000000654 86.0
TLS3_k127_5520074_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 308.0
TLS3_k127_5520074_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000006518 269.0
TLS3_k127_5520074_2 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively K04099,K04101 - 1.13.11.57,1.13.11.8 0.0000000000000000000000000000000000357 145.0
TLS3_k127_5520074_3 PFAM NUDIX hydrolase - - - 0.000000000000000000000000000000001206 137.0
TLS3_k127_5520074_4 Aromatic-ring-opening dioxygenase LigAB, LigA subunit - - - 0.0002488 47.0
TLS3_k127_5521448_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 1.922e-207 664.0
TLS3_k127_5521448_1 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 3.989e-202 651.0
TLS3_k127_5521448_10 alcohol dehydrogenase K00001,K00008 - 1.1.1.1,1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 297.0
TLS3_k127_5521448_11 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 289.0
TLS3_k127_5521448_12 Cytochrome oxidase assembly protein K02259,K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005403 287.0
TLS3_k127_5521448_13 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003078 271.0
TLS3_k127_5521448_14 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000002287 250.0
TLS3_k127_5521448_15 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005991 248.0
TLS3_k127_5521448_16 Domain of unknown function DUF108 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003591 238.0
TLS3_k127_5521448_17 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000721 203.0
TLS3_k127_5521448_18 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000001236 183.0
TLS3_k127_5521448_19 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000004011 170.0
TLS3_k127_5521448_2 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 563.0
TLS3_k127_5521448_20 Protein of unknown function (DUF420) K08976 - - 0.0000000000000000000000000000000000000007621 152.0
TLS3_k127_5521448_21 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000001226 151.0
TLS3_k127_5521448_22 Pfam:DUF59 K02612 - - 0.000000000000000000000000000000000003613 142.0
TLS3_k127_5521448_23 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000002999 149.0
TLS3_k127_5521448_24 Belongs to the ompA family - - - 0.000000000000000000000000001014 121.0
TLS3_k127_5521448_25 Glycine cleavage H-protein - - - 0.000000000000001327 79.0
TLS3_k127_5521448_26 Excisionase - - - 0.000000006188 65.0
TLS3_k127_5521448_27 NMT1/THI5 like K02051 - - 0.00001235 57.0
TLS3_k127_5521448_29 integral membrane protein - - - 0.00003115 53.0
TLS3_k127_5521448_3 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 532.0
TLS3_k127_5521448_30 Belongs to the ompA family - - - 0.0001799 49.0
TLS3_k127_5521448_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 401.0
TLS3_k127_5521448_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 377.0
TLS3_k127_5521448_6 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 368.0
TLS3_k127_5521448_7 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009362 362.0
TLS3_k127_5521448_8 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 329.0
TLS3_k127_5521448_9 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 302.0
TLS3_k127_558024_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0 1103.0
TLS3_k127_558024_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 481.0
TLS3_k127_558024_10 bacteriocin transport - - - 0.0000000000000000000000000000000000000000000000000000000008754 211.0
TLS3_k127_558024_11 methyltransferase K22269 - 2.1.1.343 0.00000000000000000000000000000000000000000000000000000002872 209.0
TLS3_k127_558024_12 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000006361 195.0
TLS3_k127_558024_13 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000003272 195.0
TLS3_k127_558024_14 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000008055 179.0
TLS3_k127_558024_15 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000001074 139.0
TLS3_k127_558024_16 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000001564 117.0
TLS3_k127_558024_17 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000008923 128.0
TLS3_k127_558024_18 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000003194 110.0
TLS3_k127_558024_19 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000343 106.0
TLS3_k127_558024_2 RNA ligase activity K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 465.0
TLS3_k127_558024_20 repeat protein - - - 0.00000000000000000000007061 112.0
TLS3_k127_558024_21 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000001209 102.0
TLS3_k127_558024_22 biopolymer transport protein K03559 - - 0.00000000000000000002131 96.0
TLS3_k127_558024_23 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.0000000003452 63.0
TLS3_k127_558024_24 von Willebrand factor type A domain K07114 - - 0.0000002891 63.0
TLS3_k127_558024_25 repeat protein - - - 0.00004921 55.0
TLS3_k127_558024_26 TonB C terminal K03832 - - 0.0001502 53.0
TLS3_k127_558024_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 366.0
TLS3_k127_558024_4 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 329.0
TLS3_k127_558024_5 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001616 285.0
TLS3_k127_558024_6 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000222 271.0
TLS3_k127_558024_7 Helicase ATP-dependent domain protein K03579 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000009995 256.0
TLS3_k127_558024_8 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000001032 243.0
TLS3_k127_558024_9 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000006328 235.0
TLS3_k127_5611058_0 glutamate dehydrogenase [NAD(P)+] activity K00261,K00262 - 1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 426.0
TLS3_k127_5611058_1 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000002785 245.0
TLS3_k127_5611058_2 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000745 202.0
TLS3_k127_5611058_3 phosphatase activity K07025 - - 0.0000000000000000000000000000000000000000000000004001 183.0
TLS3_k127_5611058_4 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000009973 150.0
TLS3_k127_5611058_5 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000005158 140.0
TLS3_k127_5611058_6 Histidine kinase - - - 0.00000000000000000000000006839 115.0
TLS3_k127_5611058_7 Rieske [2Fe-2S] domain - - - 0.00000000000000000000009332 102.0
TLS3_k127_5611058_8 Rieske 2Fe-2S - - - 0.00000000000000000003912 96.0
TLS3_k127_56248_0 ATPase associated with various cellular activities, AAA_5 K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 477.0
TLS3_k127_56248_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005573 287.0
TLS3_k127_56248_2 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000106 169.0
TLS3_k127_5643209_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 7.126e-270 842.0
TLS3_k127_5643209_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.466e-221 691.0
TLS3_k127_5643209_10 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 328.0
TLS3_k127_5643209_11 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005929 307.0
TLS3_k127_5643209_12 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 291.0
TLS3_k127_5643209_13 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001488 269.0
TLS3_k127_5643209_14 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000002409 271.0
TLS3_k127_5643209_15 TIM-barrel fold metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003477 260.0
TLS3_k127_5643209_16 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000001099 253.0
TLS3_k127_5643209_17 ACT domain K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000001331 233.0
TLS3_k127_5643209_18 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000001884 242.0
TLS3_k127_5643209_19 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000002129 217.0
TLS3_k127_5643209_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 592.0
TLS3_k127_5643209_20 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000002162 214.0
TLS3_k127_5643209_21 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000004979 177.0
TLS3_k127_5643209_22 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000001569 177.0
TLS3_k127_5643209_23 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000003526 148.0
TLS3_k127_5643209_24 Universal bacterial protein YeaZ K14742 - - 0.0000000000000000000000000000000001146 143.0
TLS3_k127_5643209_25 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000153 143.0
TLS3_k127_5643209_26 cellulose binding - - - 0.000000000000000000000000001504 125.0
TLS3_k127_5643209_27 NMT1-like family - - - 0.0000000000000000000001279 109.0
TLS3_k127_5643209_28 NMT1-like family K02051 - - 0.000000000000006644 84.0
TLS3_k127_5643209_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 494.0
TLS3_k127_5643209_30 TonB C terminal K03646 - - 0.0002115 50.0
TLS3_k127_5643209_31 NMT1-like family K02051 - - 0.0003761 47.0
TLS3_k127_5643209_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 469.0
TLS3_k127_5643209_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 452.0
TLS3_k127_5643209_6 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 453.0
TLS3_k127_5643209_7 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 434.0
TLS3_k127_5643209_8 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005815 374.0
TLS3_k127_5643209_9 SMART PDZ DHR GLGF domain protein K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 357.0
TLS3_k127_5693292_0 Domain of unknown function (DUF4112) - - - 0.00000000000000000000000000018 122.0
TLS3_k127_5693292_1 BON domain - - - 0.0000000000000000004173 92.0
TLS3_k127_5693292_2 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0000000000001542 72.0
TLS3_k127_573431_0 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 467.0
TLS3_k127_573431_1 Polysaccharide export protein K01991,K20988 - - 0.00000000000000000000000000002234 131.0
TLS3_k127_5825165_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 458.0
TLS3_k127_5825165_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 417.0
TLS3_k127_5825165_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 304.0
TLS3_k127_5825165_3 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000001202 262.0
TLS3_k127_5825165_4 PFAM cytochrome c assembly protein - - - 0.000000000000000102 81.0
TLS3_k127_5825165_5 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000002372 81.0
TLS3_k127_5825165_6 Cytochrome C556 - - - 0.000000004906 64.0
TLS3_k127_5825165_7 Redoxin K03386 - 1.11.1.15 0.0001907 45.0
TLS3_k127_592488_0 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 318.0
TLS3_k127_592488_1 COG1164 Oligoendopeptidase F K08602 - - 0.00000000002378 66.0
TLS3_k127_5954226_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.362e-229 729.0
TLS3_k127_5954226_1 PFAM FAD dependent oxidoreductase K09835,K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,5.2.1.13 2.232e-214 678.0
TLS3_k127_5954226_10 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000359 178.0
TLS3_k127_5954226_11 Yqey-like protein K09117 - - 0.000000000000000000000000000000000008379 141.0
TLS3_k127_5954226_12 B12 binding domain - - - 0.000000000000000000000003968 113.0
TLS3_k127_5954226_13 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000005716 96.0
TLS3_k127_5954226_14 protein, putative amidase K01470 - 3.5.2.10 0.0000000000005914 74.0
TLS3_k127_5954226_15 PFAM Colicin V production protein K03558 - - 0.000007404 55.0
TLS3_k127_5954226_16 sequence-specific DNA binding - - - 0.0002298 52.0
TLS3_k127_5954226_17 Protein of unknown function (DUF1722) - - - 0.0002298 44.0
TLS3_k127_5954226_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.147e-198 638.0
TLS3_k127_5954226_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 357.0
TLS3_k127_5954226_4 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 315.0
TLS3_k127_5954226_5 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 293.0
TLS3_k127_5954226_6 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 286.0
TLS3_k127_5954226_7 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000007978 269.0
TLS3_k127_5954226_8 Carotenoid biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000007337 201.0
TLS3_k127_5954226_9 Belongs to the FPP GGPP synthase family - - - 0.0000000000000000000000000000000000000000000000002208 192.0
TLS3_k127_5974835_0 PFAM glycosyl transferase family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 5.193e-268 844.0
TLS3_k127_5974835_1 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 436.0
TLS3_k127_5974835_10 GTP binding K09767 GO:0000049,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000006622 194.0
TLS3_k127_5974835_11 MlaC protein - - - 0.0000000000000000000000000000000000000000001418 171.0
TLS3_k127_5974835_12 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000004203 162.0
TLS3_k127_5974835_13 diguanylate cyclase activity K02000,K04767,K05847,K07168,K09137 - 3.6.3.32 0.000000000000000000000001253 109.0
TLS3_k127_5974835_14 DoxX K03885,K16937 - 1.6.99.3,1.8.5.2 0.000000000000000000000003695 111.0
TLS3_k127_5974835_15 PFAM Rieske 2Fe-2S K00363 - 1.7.1.15 0.00000000009322 67.0
TLS3_k127_5974835_16 Dehydrogenase - - - 0.00000065 51.0
TLS3_k127_5974835_17 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00003067 55.0
TLS3_k127_5974835_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 407.0
TLS3_k127_5974835_3 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 324.0
TLS3_k127_5974835_4 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 319.0
TLS3_k127_5974835_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 301.0
TLS3_k127_5974835_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001755 263.0
TLS3_k127_5974835_7 TraB family K09973 - - 0.000000000000000000000000000000000000000000000000000000000000000001764 237.0
TLS3_k127_5974835_8 SelR domain K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000004633 223.0
TLS3_k127_5974835_9 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000004393 198.0
TLS3_k127_5987384_0 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 406.0
TLS3_k127_5987384_1 metal-dependent hydrolase of the TIM-barrel fold K03392,K22213 - 4.1.1.45,4.1.1.52 0.000000000000000000000000001136 126.0
TLS3_k127_6043650_0 Domain of unknown function (DUF3536) - - - 2.978e-266 832.0
TLS3_k127_6043650_1 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 8.49e-200 644.0
TLS3_k127_6043650_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 596.0
TLS3_k127_6043650_3 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 466.0
TLS3_k127_6043650_4 Polysaccharide export protein K01991 - - 0.000000000000000000000000000000000000000003556 169.0
TLS3_k127_6043650_5 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000003898 166.0
TLS3_k127_6043650_6 COG0250 Transcription antiterminator K05785 GO:0001000,GO:0001073,GO:0001121,GO:0001124,GO:0003674,GO:0003676,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008494,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032270,GO:0032774,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045182,GO:0045727,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090079,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000741 78.0
TLS3_k127_6081408_0 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.0 1164.0
TLS3_k127_6081408_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 345.0
TLS3_k127_6081408_2 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000401 216.0
TLS3_k127_6081408_3 SnoaL-like domain - - - 0.000000000000000000000000001323 119.0
TLS3_k127_6081408_4 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000002568 114.0
TLS3_k127_6081408_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000005405 59.0
TLS3_k127_6087823_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009121 403.0
TLS3_k127_6087823_1 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000001843 223.0
TLS3_k127_6087823_2 Beta-lactamase superfamily domain - - - 0.000000000000000000000004096 109.0
TLS3_k127_6087823_3 Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C K06137 - 1.3.3.11 0.0000000000000000000006057 106.0
TLS3_k127_6099037_0 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.00000003734 64.0
TLS3_k127_6099037_1 Endoribonuclease L-PSP - - - 0.00002729 53.0
TLS3_k127_61443_0 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 293.0
TLS3_k127_61443_1 SMART tyrosine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000001059 237.0
TLS3_k127_61443_2 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000361 186.0
TLS3_k127_61443_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000007068 82.0
TLS3_k127_61443_4 TIGRFAM 2-aminoethylphosphonate ABC transport system, 1-aminoethylphosphonate-binding protein component K02012 - - 0.000000000000001835 87.0
TLS3_k127_61443_5 NMT1-like family K02051 - - 0.00000000002078 75.0
TLS3_k127_6170201_0 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006709 429.0
TLS3_k127_6170201_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 342.0
TLS3_k127_6170201_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000115 283.0
TLS3_k127_6185043_0 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000006812 236.0
TLS3_k127_6185043_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000003579 220.0
TLS3_k127_6185043_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000001848 186.0
TLS3_k127_6185043_3 Alpha beta hydrolase - - - 0.00000000000000000000000000000002442 137.0
TLS3_k127_6185043_4 oligosaccharyl transferase activity - - - 0.00000000000000000000000000205 128.0
TLS3_k127_6185043_5 NMT1-like family K02051 - - 0.00000000001829 75.0
TLS3_k127_6185043_6 thiamine-containing compound biosynthetic process K02051 - - 0.00000001154 66.0
TLS3_k127_6195337_0 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 529.0
TLS3_k127_6195337_1 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 309.0
TLS3_k127_6195337_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009241 274.0
TLS3_k127_6195337_3 TIM-barrel fold metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002115 258.0
TLS3_k127_6195337_4 Catalyzes the conversion of maleate to fumarate K01799 - 5.2.1.1 0.000000000000000000000002828 111.0
TLS3_k127_6195337_5 YCII-related domain - - - 0.00000000000000000000007406 101.0
TLS3_k127_6195337_6 Universal stress protein family - - - 0.00000000000000000004371 95.0
TLS3_k127_6195337_7 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000002541 80.0
TLS3_k127_6195337_8 Asp/Glu/Hydantoin racemase K01799 - 5.2.1.1 0.0004293 46.0
TLS3_k127_6202851_0 GTP-binding protein TypA K06207 - - 3.107e-234 739.0
TLS3_k127_6202851_1 (ABC) transporter K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 574.0
TLS3_k127_6202851_10 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005223 280.0
TLS3_k127_6202851_11 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000005595 256.0
TLS3_k127_6202851_12 Putative aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000007697 222.0
TLS3_k127_6202851_13 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000001776 181.0
TLS3_k127_6202851_14 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000001983 159.0
TLS3_k127_6202851_15 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000000189 147.0
TLS3_k127_6202851_16 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000000000000000000000000004595 127.0
TLS3_k127_6202851_17 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000009501 116.0
TLS3_k127_6202851_18 AsmA-like C-terminal region - - - 0.00000000000000000622 100.0
TLS3_k127_6202851_19 glutaredoxin 2 - - - 0.00000000000006872 76.0
TLS3_k127_6202851_2 ABC transporter transmembrane K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 477.0
TLS3_k127_6202851_20 NMT1/THI5 like K02051 - - 0.0000000000004742 77.0
TLS3_k127_6202851_21 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system - - - 0.000000000003325 68.0
TLS3_k127_6202851_3 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 395.0
TLS3_k127_6202851_4 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 389.0
TLS3_k127_6202851_5 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 375.0
TLS3_k127_6202851_6 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 381.0
TLS3_k127_6202851_7 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 361.0
TLS3_k127_6202851_8 Divalent cation transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007643 331.0
TLS3_k127_6202851_9 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 295.0
TLS3_k127_6247937_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 4.637e-249 777.0
TLS3_k127_6247937_1 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 479.0
TLS3_k127_6247937_10 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.0000000000000000000000000000000001716 138.0
TLS3_k127_6247937_11 Belongs to the ompA family K03286 - - 0.0000000000000000000000000001024 124.0
TLS3_k127_6247937_12 transglycosylase K08309 - - 0.0000000000000000003127 96.0
TLS3_k127_6247937_13 Tetratricopeptide repeat - - - 0.0000001104 66.0
TLS3_k127_6247937_2 Domain of unknown function (DUF3536) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 460.0
TLS3_k127_6247937_3 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 440.0
TLS3_k127_6247937_4 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009978 283.0
TLS3_k127_6247937_5 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000004257 219.0
TLS3_k127_6247937_6 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000003749 202.0
TLS3_k127_6247937_7 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.0000000000000000000000000000000000000000000007654 171.0
TLS3_k127_6247937_8 Protein of unknown function (DUF1318) - - - 0.0000000000000000000000000000000000000000006611 164.0
TLS3_k127_6247937_9 Protein conserved in bacteria - - - 0.00000000000000000000000000000000006283 155.0
TLS3_k127_6253478_0 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 582.0
TLS3_k127_6253478_1 PFAM Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 350.0
TLS3_k127_6253478_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000004327 250.0
TLS3_k127_6253478_3 Met-10+ like-protein - - - 0.00000000000000000000000000000000000000000002951 169.0
TLS3_k127_6253478_4 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000000000000128 143.0
TLS3_k127_6253478_5 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000001917 118.0
TLS3_k127_6253478_6 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 GO:0003674,GO:0005215 - 0.0000000000000000000407 102.0
TLS3_k127_6253478_7 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000002143 100.0
TLS3_k127_6262364_0 Helix-hairpin-helix containing domain K03581 - 3.1.11.5 1.974e-209 674.0
TLS3_k127_6262364_1 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 371.0
TLS3_k127_6262364_2 maleate cis-trans isomerase K01799 - 5.2.1.1 0.00000000000000000000000000000000000000001622 163.0
TLS3_k127_6262364_3 lactoylglutathione lyase activity - - - 0.0000000004652 61.0
TLS3_k127_6300088_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 GO:0000166,GO:0003674,GO:0003824,GO:0004362,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0015037,GO:0015038,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071949,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 572.0
TLS3_k127_6300088_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 370.0
TLS3_k127_6300088_2 lactate metabolic process K00113 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 368.0
TLS3_k127_6300088_3 Iron-containing redox enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 317.0
TLS3_k127_6300088_4 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 308.0
TLS3_k127_6300088_5 major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003403 259.0
TLS3_k127_6300088_6 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000004035 102.0
TLS3_k127_6300088_7 Amidohydrolase K07045,K14333,K20941 - 4.1.1.103,4.1.1.46 0.0000000000000000000622 103.0
TLS3_k127_6300088_8 Protein of unknown function (DUF861) - - - 0.000000000000000003572 90.0
TLS3_k127_6300088_9 Haem-degrading - - - 0.00000004088 55.0
TLS3_k127_6301424_0 Aldehyde dehydrogenase family K00131 - 1.2.1.9 5.053e-229 717.0
TLS3_k127_6301424_1 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 322.0
TLS3_k127_6301424_10 - - - - 0.000000095 59.0
TLS3_k127_6301424_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 310.0
TLS3_k127_6301424_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 318.0
TLS3_k127_6301424_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000004603 226.0
TLS3_k127_6301424_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000004129 211.0
TLS3_k127_6301424_6 - - - - 0.0000000000000000000000000000001319 131.0
TLS3_k127_6301424_7 YGGT family K02221 - - 0.000000000000000000000000000002805 122.0
TLS3_k127_6301424_8 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000004093 109.0
TLS3_k127_6407340_0 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000002405 132.0
TLS3_k127_6407340_1 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000009405 108.0
TLS3_k127_6421000_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1358.0
TLS3_k127_6421000_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002155 271.0
TLS3_k127_6421000_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000004484 215.0
TLS3_k127_6421000_3 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000272 155.0
TLS3_k127_6421000_4 Pfam Amidohydrolase K07045 - - 0.00000000000000000000000000000000006148 148.0
TLS3_k127_6421000_5 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000361 112.0
TLS3_k127_6477147_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 311.0
TLS3_k127_6477147_1 benzoyl-CoA reductase K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 305.0
TLS3_k127_6477147_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007726 282.0
TLS3_k127_6477147_3 NAD dependent epimerase/dehydratase family K07535 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005833 277.0
TLS3_k127_6477147_4 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000000000008844 237.0
TLS3_k127_655838_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 490.0
TLS3_k127_655838_1 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000002039 138.0
TLS3_k127_655838_2 Cupin domain - - - 0.00001362 51.0
TLS3_k127_6561591_0 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000005637 224.0
TLS3_k127_6561591_1 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000001436 219.0
TLS3_k127_6561591_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000004062 190.0
TLS3_k127_6561591_3 ZIP Zinc transporter K07238,K16267 - - 0.0000000000000000000000000001123 125.0
TLS3_k127_6561591_4 Glycosyl transferase family 41 K09667 GO:0000003,GO:0000123,GO:0000785,GO:0000791,GO:0001678,GO:0001932,GO:0001933,GO:0001934,GO:0002119,GO:0002164,GO:0002237,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006040,GO:0006041,GO:0006047,GO:0006048,GO:0006073,GO:0006091,GO:0006109,GO:0006110,GO:0006111,GO:0006112,GO:0006139,GO:0006140,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006470,GO:0006473,GO:0006475,GO:0006479,GO:0006486,GO:0006493,GO:0006508,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007444,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008150,GO:0008152,GO:0008194,GO:0008213,GO:0008219,GO:0008289,GO:0008361,GO:0008375,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009791,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010675,GO:0010799,GO:0010801,GO:0010876,GO:0010906,GO:0010941,GO:0012501,GO:0012505,GO:0015980,GO:0016020,GO:0016043,GO:0016262,GO:0016311,GO:0016407,GO:0016410,GO:0016485,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016579,GO:0016740,GO:0016746,GO:0016747,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019725,GO:0019904,GO:0019915,GO:0022607,GO:0023051,GO:0023052,GO:0030141,GO:0030162,GO:0030246,GO:0030808,GO:0030811,GO:0030900,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031667,GO:0031974,GO:0031981,GO:0031982,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032387,GO:0032434,GO:0032435,GO:0032496,GO:0032501,GO:0032502,GO:0032535,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033135,GO:0033137,GO:0033157,GO:0033218,GO:0033500,GO:0033993,GO:0034284,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035020,GO:0035091,GO:0035220,GO:0035295,GO:0035556,GO:0036094,GO:0036211,GO:0036477,GO:0040024,GO:0042176,GO:0042177,GO:0042221,GO:0042277,GO:0042325,GO:0042326,GO:0042327,GO:0042578,GO:0042588,GO:0042592,GO:0042593,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043255,GO:0043412,GO:0043413,GO:0043414,GO:0043434,GO:0043467,GO:0043470,GO:0043543,GO:0043933,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045475,GO:0045793,GO:0045861,GO:0045862,GO:0045893,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046349,GO:0046483,GO:0046578,GO:0046626,GO:0048015,GO:0048017,GO:0048029,GO:0048311,GO:0048312,GO:0048471,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051056,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051223,GO:0051224,GO:0051235,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051291,GO:0051568,GO:0051604,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0051707,GO:0051716,GO:0055082,GO:0055086,GO:0055114,GO:0060255,GO:0060322,GO:0060341,GO:0060429,GO:0060548,GO:0061085,GO:0061087,GO:0061136,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0070201,GO:0070206,GO:0070207,GO:0070208,GO:0070646,GO:0070647,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071375,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0080182,GO:0090066,GO:0090087,GO:0090313,GO:0090315,GO:0090317,GO:0097237,GO:0097363,GO:0097458,GO:0097708,GO:0099503,GO:0120025,GO:0140096,GO:1900037,GO:1900038,GO:1900076,GO:1900180,GO:1900182,GO:1900371,GO:1900542,GO:1901071,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901799,GO:1901981,GO:1902275,GO:1902493,GO:1902494,GO:1902531,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903426,GO:1903428,GO:1903506,GO:1903508,GO:1903533,GO:1903578,GO:1903827,GO:1903828,GO:1903829,GO:1904950,GO:1905269,GO:1905475,GO:1905476,GO:1990234,GO:2000058,GO:2000059,GO:2000112,GO:2000377,GO:2000379,GO:2001141,GO:2001169,GO:2001252 2.4.1.255 0.00000000000000000000000309 115.0
TLS3_k127_6579214_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 564.0
TLS3_k127_6579214_1 Nucleotidyl transferase K00978 - 2.7.7.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 429.0
TLS3_k127_6579214_2 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000009866 183.0
TLS3_k127_6623662_0 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006862 441.0
TLS3_k127_6623662_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 396.0
TLS3_k127_6623662_10 Protein of unknown function (DUF3309) - - - 0.0000000000000000004379 87.0
TLS3_k127_6623662_11 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000003989 79.0
TLS3_k127_6623662_2 metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 329.0
TLS3_k127_6623662_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001329 270.0
TLS3_k127_6623662_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000001315 240.0
TLS3_k127_6623662_5 Anabaena sensory rhodopsin transducer - - - 0.000000000000000000000000000000000000000000000000000000007046 201.0
TLS3_k127_6623662_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000004128 177.0
TLS3_k127_6623662_7 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000006878 173.0
TLS3_k127_6637187_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 382.0
TLS3_k127_6637187_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002564 260.0
TLS3_k127_6637187_10 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K13039 - 4.1.1.79 0.000000000000000001826 93.0
TLS3_k127_6637187_11 Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c - GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.000000009502 60.0
TLS3_k127_6637187_12 Redoxin - - - 0.0005076 46.0
TLS3_k127_6637187_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004011 243.0
TLS3_k127_6637187_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000002018 224.0
TLS3_k127_6637187_4 pfam nudix - - - 0.00000000000000000000000000000000000000000000000000000000001755 209.0
TLS3_k127_6637187_5 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000004869 214.0
TLS3_k127_6637187_6 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000228 183.0
TLS3_k127_6637187_7 Alpha beta - - - 0.00000000000000000000000000000001168 138.0
TLS3_k127_6637187_8 Uncharacterised BCR, YnfA/UPF0060 family K09771 - - 0.0000000000000000000000000000001938 125.0
TLS3_k127_6637187_9 sulfopyruvate decarboxylase, alpha subunit K06034 - 4.1.1.79 0.00000000000000000000000000002645 123.0
TLS3_k127_6676504_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 408.0
TLS3_k127_6676504_1 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000000000000000000000000000000000007003 168.0
TLS3_k127_6676504_2 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000609 166.0
TLS3_k127_6676504_3 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000008473 143.0
TLS3_k127_6697137_0 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 1.261e-201 631.0
TLS3_k127_6697137_1 permease - - - 0.00000008056 55.0
TLS3_k127_6731239_0 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 388.0
TLS3_k127_6731239_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000003495 160.0
TLS3_k127_6836523_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.000000000000000000000000000000000000000002231 162.0
TLS3_k127_6836523_1 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000001045 149.0
TLS3_k127_6836523_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000356 124.0
TLS3_k127_6836523_3 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000007324 92.0
TLS3_k127_685985_0 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008793 305.0
TLS3_k127_685985_1 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000000000000000000000000000000000000005634 176.0
TLS3_k127_6883187_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 606.0
TLS3_k127_6883187_1 Cupin domain K00450 - 1.13.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 370.0
TLS3_k127_6883187_10 Transposase K07494 - - 0.00000000000000000000000000000001711 128.0
TLS3_k127_6883187_11 methionyl-tRNA aminoacylation K01874,K01890,K06878 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 0.00000000000000000000000000000002969 130.0
TLS3_k127_6883187_12 Ferric uptake regulator, Fur family K09825 - - 0.00000000000000000000004336 103.0
TLS3_k127_6883187_13 DDE superfamily endonuclease - - - 0.0000000000000000002932 96.0
TLS3_k127_6883187_14 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000007469 76.0
TLS3_k127_6883187_2 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 344.0
TLS3_k127_6883187_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 335.0
TLS3_k127_6883187_4 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 287.0
TLS3_k127_6883187_5 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005897 256.0
TLS3_k127_6883187_6 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000004403 158.0
TLS3_k127_6883187_7 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000004771 150.0
TLS3_k127_6883187_8 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000003291 145.0
TLS3_k127_6883187_9 Zn-dependent hydrolases of the - - - 0.00000000000000000000000000000000008795 144.0
TLS3_k127_6884948_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 569.0
TLS3_k127_6884948_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 503.0
TLS3_k127_6884948_10 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000001672 166.0
TLS3_k127_6884948_11 Transmembrane secretion effector - - - 0.00000000000000000000000000003576 126.0
TLS3_k127_6884948_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000001022 111.0
TLS3_k127_6884948_13 NMT1-like family K02051 - - 0.00000000000000000000002589 111.0
TLS3_k127_6884948_14 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 0.000000000000000000817 96.0
TLS3_k127_6884948_15 Putative zinc-finger - - - 0.0000000001594 68.0
TLS3_k127_6884948_17 - - - - 0.00000004412 64.0
TLS3_k127_6884948_2 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 434.0
TLS3_k127_6884948_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 400.0
TLS3_k127_6884948_4 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 295.0
TLS3_k127_6884948_5 TIM-barrel fold metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005273 254.0
TLS3_k127_6884948_6 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000001236 247.0
TLS3_k127_6884948_7 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000004375 240.0
TLS3_k127_6884948_8 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000001775 215.0
TLS3_k127_6884948_9 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000000000004154 191.0
TLS3_k127_6928012_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.055e-244 773.0
TLS3_k127_6928012_1 multicopper oxidases K06324 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 511.0
TLS3_k127_6928012_10 Cytokinin riboside 5'-monophosphate phosphoribohydrolase K06966 - 3.2.2.10 0.0002643 43.0
TLS3_k127_6928012_2 FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 408.0
TLS3_k127_6928012_3 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 332.0
TLS3_k127_6928012_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005074 275.0
TLS3_k127_6928012_5 Sulphur transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000001073 240.0
TLS3_k127_6928012_6 Sulphur transport - - - 0.00000000000000000000000000000000000000000000000000000000000000004847 227.0
TLS3_k127_6928012_7 Uncharacterised protein family UPF0066 - - - 0.00000000000001356 75.0
TLS3_k127_6928012_8 UPF0365 protein - - - 0.0000000004272 63.0
TLS3_k127_6928012_9 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.0001414 51.0
TLS3_k127_6950042_0 B12 binding domain - - - 2.231e-284 879.0
TLS3_k127_6950042_1 PFAM Alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 602.0
TLS3_k127_6950042_10 Major Facilitator Superfamily - - - 0.000000000000000000000000000339 128.0
TLS3_k127_6950042_11 CAAX protease self-immunity - - - 0.0000000000000000006697 91.0
TLS3_k127_6950042_12 NMT1-like family K02051,K15553 - - 0.00000002156 66.0
TLS3_k127_6950042_2 MutL protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 368.0
TLS3_k127_6950042_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 310.0
TLS3_k127_6950042_4 Encapsulating protein for peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 297.0
TLS3_k127_6950042_5 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000003284 229.0
TLS3_k127_6950042_6 secretion ATPase, PEP-CTERM locus subfamily K02450 - - 0.000000000000000000000000000000000000000000000000000004204 209.0
TLS3_k127_6950042_7 Protein involved in outer membrane biogenesis K07289,K09800 - - 0.0000000000000000000000000000000000000000000000000004212 210.0
TLS3_k127_6950042_8 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000006589 193.0
TLS3_k127_6950042_9 Evidence 4 Homologs of previously reported genes of K09700 - - 0.00000000000000000000000000000000000003717 146.0
TLS3_k127_6954262_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008785 391.0
TLS3_k127_6954262_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 385.0
TLS3_k127_6954262_2 Catalyzes the conversion of feruloyl-CoA to vanillin and acetyl-CoA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 351.0
TLS3_k127_6954262_3 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 306.0
TLS3_k127_6954262_4 PFAM Acetyltransferase (GNAT) family K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000000000001305 222.0
TLS3_k127_6954262_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000003644 200.0
TLS3_k127_6954262_6 NMT1-like family - - - 0.00000000000000000000000105 112.0
TLS3_k127_6954262_7 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000003479 108.0
TLS3_k127_6954262_8 NMT1-like family K02051,K15551 - - 0.000000008372 63.0
TLS3_k127_6996224_0 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003918 260.0
TLS3_k127_6996224_1 deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000001454 146.0
TLS3_k127_6996224_2 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000002661 136.0
TLS3_k127_6996224_3 Polysaccharide deacetylase - - - 0.0000000000000000000000000000003333 134.0
TLS3_k127_6996224_4 DsrE/DsrF-like family - - - 0.0000000000000000000000001865 107.0
TLS3_k127_6996224_5 thiamine-containing compound biosynthetic process K02051 - - 0.000004676 56.0
TLS3_k127_6996224_6 cellulase activity - - - 0.00006316 52.0
TLS3_k127_700233_0 G-rich domain on putative tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002725 249.0
TLS3_k127_700233_1 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000008073 234.0
TLS3_k127_700233_2 glycosyl transferase family 2 - - - 0.0000000000000000000000003091 117.0
TLS3_k127_703004_0 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 477.0
TLS3_k127_703004_1 tRNA nucleotidyltransferase poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 407.0
TLS3_k127_703004_2 Belongs to the UbiD family K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 398.0
TLS3_k127_703004_3 Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 377.0
TLS3_k127_703004_4 PFAM Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 339.0
TLS3_k127_703004_5 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005103 249.0
TLS3_k127_703004_6 KR domain K00059,K10617 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000007543 242.0
TLS3_k127_703004_7 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000171 172.0
TLS3_k127_703004_8 Pas domain - - - 0.00000000000000000000000009464 112.0
TLS3_k127_703004_9 Domain of unknown function (DUF4126) - - - 0.0004604 43.0
TLS3_k127_7062616_0 alkylbase DNA N-glycosylase activity K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000007869 225.0
TLS3_k127_7062616_1 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000003385 211.0
TLS3_k127_7062616_2 nucleoside 2-deoxyribosyltransferase - - - 0.000000000000000000000000000000000001542 148.0
TLS3_k127_7069456_0 FAD linked oxidases, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000008174 194.0
TLS3_k127_7069456_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000007801 144.0
TLS3_k127_7069456_2 Guanyl-specific ribonuclease Sa - - - 0.0000000000000000000000000000000000009892 141.0
TLS3_k127_7069456_3 Barstar (barnase inhibitor) - - - 0.0000000000000000000000003438 111.0
TLS3_k127_7069456_4 TIGRFAM competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.0000000000000000000004035 102.0
TLS3_k127_7082177_0 chlorophyll binding K02051,K03286 - - 0.00000000000000000000005568 108.0
TLS3_k127_7082177_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.00000004259 63.0
TLS3_k127_7113205_0 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 424.0
TLS3_k127_7113205_1 protein histidine kinase activity K07315,K07641,K10819,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 387.0
TLS3_k127_7113205_2 - - - - 0.000000000000000000000000000000000000000000000007217 177.0
TLS3_k127_7113205_3 - - - - 0.000000000000000000000000000000000009286 140.0
TLS3_k127_7113205_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000002124 136.0
TLS3_k127_7113205_5 Histidine kinase - - - 0.00000000000000000000000002094 116.0
TLS3_k127_7113205_6 PFAM ATP-binding region ATPase domain protein K07709 - 2.7.13.3 0.0000000000000001653 81.0
TLS3_k127_7113205_7 UPF0391 membrane protein - - - 0.00000000000001068 76.0
TLS3_k127_7116677_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1230.0
TLS3_k127_7116677_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 6.853e-313 968.0
TLS3_k127_7116677_10 twitching motility protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 511.0
TLS3_k127_7116677_11 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 500.0
TLS3_k127_7116677_12 Belongs to the aldehyde dehydrogenase family K00135,K22445 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 478.0
TLS3_k127_7116677_13 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 435.0
TLS3_k127_7116677_14 SAICAR synthetase K01923,K01945,K03566 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 394.0
TLS3_k127_7116677_15 Succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 388.0
TLS3_k127_7116677_16 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 380.0
TLS3_k127_7116677_17 Methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008224 335.0
TLS3_k127_7116677_18 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 328.0
TLS3_k127_7116677_19 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 301.0
TLS3_k127_7116677_2 succinate dehydrogenase, flavoprotein subunit K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 1.708e-290 901.0
TLS3_k127_7116677_20 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 301.0
TLS3_k127_7116677_21 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000008743 267.0
TLS3_k127_7116677_22 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000007462 252.0
TLS3_k127_7116677_23 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000001138 222.0
TLS3_k127_7116677_24 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000001257 208.0
TLS3_k127_7116677_25 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000006841 193.0
TLS3_k127_7116677_26 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000007114 188.0
TLS3_k127_7116677_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000009933 177.0
TLS3_k127_7116677_28 Membrane proteins related to metalloendopeptidases K06194 - - 0.000000000000000000000000000000000000000001487 166.0
TLS3_k127_7116677_29 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000002258 150.0
TLS3_k127_7116677_3 PFAM FAD linked oxidase domain protein - - - 7.926e-271 856.0
TLS3_k127_7116677_30 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000000002344 143.0
TLS3_k127_7116677_31 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000001001 130.0
TLS3_k127_7116677_32 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.00000000000000000000000000000002039 138.0
TLS3_k127_7116677_33 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000003097 120.0
TLS3_k127_7116677_34 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000007405 101.0
TLS3_k127_7116677_35 structural constituent of ribosome K02916 - - 0.000000000000000002196 86.0
TLS3_k127_7116677_36 Ferredoxin - - - 0.000000000000000008435 87.0
TLS3_k127_7116677_37 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000002224 84.0
TLS3_k127_7116677_38 TIGRFAM methyltransferase FkbM - - - 0.0000000000001394 81.0
TLS3_k127_7116677_39 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 - 3.4.19.3 0.000000000001101 76.0
TLS3_k127_7116677_4 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 1.347e-217 685.0
TLS3_k127_7116677_40 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.00000000006788 66.0
TLS3_k127_7116677_41 Putative regulatory protein - - - 0.0000005079 55.0
TLS3_k127_7116677_5 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 6.748e-217 692.0
TLS3_k127_7116677_6 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 7.145e-217 695.0
TLS3_k127_7116677_7 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 1.03e-211 667.0
TLS3_k127_7116677_8 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 604.0
TLS3_k127_7116677_9 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 582.0
TLS3_k127_7150170_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 491.0
TLS3_k127_7150170_1 TRAM domain K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 421.0
TLS3_k127_7150170_10 PFAM ATP-binding region ATPase domain protein K10819 - 2.7.13.3 0.00000000002074 73.0
TLS3_k127_7150170_11 Stage II sporulation protein M K06384 - - 0.000000001173 66.0
TLS3_k127_7150170_2 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 390.0
TLS3_k127_7150170_3 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 322.0
TLS3_k127_7150170_4 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 297.0
TLS3_k127_7150170_5 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004885 243.0
TLS3_k127_7150170_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000001846 218.0
TLS3_k127_7150170_7 PFAM Histidine triad (HIT) protein - - - 0.000000000000000000000000000000000000001402 153.0
TLS3_k127_7150170_8 nUDIX hydrolase - - - 0.000000000000000000000000000000000001067 149.0
TLS3_k127_7150170_9 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000002678 141.0
TLS3_k127_7174168_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 299.0
TLS3_k127_7191259_0 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000000000000000000000344 171.0
TLS3_k127_7191259_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000018 157.0
TLS3_k127_7191259_2 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000846 117.0
TLS3_k127_7191259_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.1,3.5.4.33 0.0000006143 52.0
TLS3_k127_7256020_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000434 264.0
TLS3_k127_7256020_1 Protein of unknown function (DUF3014) - - - 0.000000000000000000000000000000000000000000000000000000000008756 216.0
TLS3_k127_7256020_2 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000000000000000448 151.0
TLS3_k127_7256020_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.000000000000000000000000000000000001613 145.0
TLS3_k127_7259487_0 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 353.0
TLS3_k127_7259487_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 332.0
TLS3_k127_7259487_2 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 287.0
TLS3_k127_7259487_3 xaa-pro dipeptidase K01271 K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000001724 151.0
TLS3_k127_72660_0 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 366.0
TLS3_k127_72660_1 COG0604 NADPH quinone reductase and related Zn-dependent K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 341.0
TLS3_k127_72660_2 Extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols K04101 - 1.13.11.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002571 279.0
TLS3_k127_72660_3 Cysteine-rich motif following a subset of SET domains K07117 - - 0.000000000000000000000000000000000000000000004663 168.0
TLS3_k127_72660_4 Isochorismatase family - - - 0.00000000000000000000000000000000004669 145.0
TLS3_k127_72660_5 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000001924 128.0
TLS3_k127_72660_6 NMT1-like family - - - 0.00000000000000000000000000005953 129.0
TLS3_k127_72660_7 - - - - 0.000000000000000008586 86.0
TLS3_k127_72660_8 LVIVD repeat - - - 0.0000000000000008029 79.0
TLS3_k127_7279418_0 Rod shape-determining protein K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 534.0
TLS3_k127_7279418_1 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 538.0
TLS3_k127_7279418_10 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000001139 237.0
TLS3_k127_7279418_11 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000004397 212.0
TLS3_k127_7279418_12 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000001627 177.0
TLS3_k127_7279418_13 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000004057 177.0
TLS3_k127_7279418_14 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000001863 154.0
TLS3_k127_7279418_15 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000005008 150.0
TLS3_k127_7279418_16 Thioredoxin-like - - - 0.000000000000000000000000000000006442 135.0
TLS3_k127_7279418_17 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000000000000000000009319 131.0
TLS3_k127_7279418_18 rod shape-determining protein MreD K03571 - - 0.000003941 55.0
TLS3_k127_7279418_2 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008668 459.0
TLS3_k127_7279418_3 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 441.0
TLS3_k127_7279418_4 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 401.0
TLS3_k127_7279418_5 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 375.0
TLS3_k127_7279418_6 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009288 365.0
TLS3_k127_7279418_7 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006453 267.0
TLS3_k127_7279418_8 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000001595 246.0
TLS3_k127_7279418_9 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000002993 240.0
TLS3_k127_7288461_0 Ion transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 310.0
TLS3_k127_7288461_1 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000217 184.0
TLS3_k127_7288461_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000007418 89.0
TLS3_k127_7289617_0 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006997 343.0
TLS3_k127_7289617_1 Metallo-beta-lactamase superfamily K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000004119 259.0
TLS3_k127_7289617_2 cob(I)yrinic acid a,c-diamide adenosyltransferase activity K00798,K13821 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 0.00000000000000000000000000000000000001868 148.0
TLS3_k127_7289617_3 Rhodanese Homology Domain - - - 0.000000000000000000000000000001864 125.0
TLS3_k127_72918_0 Tripartite tricarboxylate transporter TctA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 387.0
TLS3_k127_72918_1 protein conserved in bacteria - - - 0.00000000000000000000000000001863 132.0
TLS3_k127_72918_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000002396 130.0
TLS3_k127_72918_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000139 114.0
TLS3_k127_73241_0 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000773 126.0
TLS3_k127_73241_1 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000000004657 99.0
TLS3_k127_73241_2 Molybdopterin-binding domain of aldehyde dehydrogenase - - - 0.000000000000002859 78.0
TLS3_k127_73241_3 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000559 86.0
TLS3_k127_7324462_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 539.0
TLS3_k127_7324462_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0002922 49.0
TLS3_k127_7330690_0 Transposase DDE domain - - - 6.364e-275 856.0
TLS3_k127_7330690_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 1.732e-203 653.0
TLS3_k127_7330690_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000001621 195.0
TLS3_k127_7330690_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000000000000000000000000000000001168 179.0
TLS3_k127_7330690_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.0000000000000000000000000000000000000003258 152.0
TLS3_k127_7330690_13 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000001009 154.0
TLS3_k127_7330690_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000003694 132.0
TLS3_k127_7330690_15 Isochorismatase family - - - 0.0000000000000006933 77.0
TLS3_k127_7330690_2 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 588.0
TLS3_k127_7330690_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 462.0
TLS3_k127_7330690_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 419.0
TLS3_k127_7330690_5 ATP synthesis coupled electron transport K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 400.0
TLS3_k127_7330690_6 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 337.0
TLS3_k127_7330690_7 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 319.0
TLS3_k127_7330690_8 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 312.0
TLS3_k127_7330690_9 Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000004249 258.0
TLS3_k127_7434970_0 Ammonium Transporter Family K03320 - - 6.83e-201 639.0
TLS3_k127_7434970_1 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 320.0
TLS3_k127_7434970_2 Carbon-nitrogen hydrolase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 305.0
TLS3_k127_7434970_3 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000001145 200.0
TLS3_k127_7434970_4 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000002132 203.0
TLS3_k127_7434970_5 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000374 190.0
TLS3_k127_7434970_6 FeoA K01356,K03709 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000002999 186.0
TLS3_k127_7434970_7 Nitrogen regulatory protein P-II K04751 - - 0.000000000000000000000000000000000000000000000003543 174.0
TLS3_k127_7434970_8 ANTAR K07183,K22010 - - 0.0000000000000000000000000000004474 128.0
TLS3_k127_7434970_9 Metallo-beta-lactamase superfamily - - - 0.0001727 48.0
TLS3_k127_7441523_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 2.728e-207 655.0
TLS3_k127_7441523_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 524.0
TLS3_k127_7441523_10 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001438 243.0
TLS3_k127_7441523_11 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000002142 195.0
TLS3_k127_7441523_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 434.0
TLS3_k127_7441523_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 380.0
TLS3_k127_7441523_4 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 377.0
TLS3_k127_7441523_5 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007201 375.0
TLS3_k127_7441523_6 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 375.0
TLS3_k127_7441523_7 Mota tolq exbb proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 343.0
TLS3_k127_7441523_8 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 327.0
TLS3_k127_7441523_9 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000289 263.0
TLS3_k127_7529689_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 377.0
TLS3_k127_7529689_1 Luciferase-like monooxygenase K00320,K14728 - 1.5.98.2 0.000000000000000000000000000000000000000001817 169.0
TLS3_k127_7529689_2 deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000002161 161.0
TLS3_k127_7529689_3 Domain of unknown function (DUF1989) K09967 - - 0.000000000000000000003638 104.0
TLS3_k127_7529689_4 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000004385 105.0
TLS3_k127_7529689_5 lactoylglutathione lyase activity K11210 - - 0.000000005853 66.0
TLS3_k127_7529689_6 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively K04101 - 1.13.11.8 0.000000009192 57.0
TLS3_k127_7529689_7 Glyoxalase-like domain - - - 0.000001965 59.0
TLS3_k127_7542996_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009753 589.0
TLS3_k127_7542996_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 580.0
TLS3_k127_7542996_10 Cyclodeaminase K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000002837 263.0
TLS3_k127_7542996_11 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000544 211.0
TLS3_k127_7542996_12 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000002777 218.0
TLS3_k127_7542996_13 Protein conserved in bacteria K09922 - - 0.00000000000000000000000000000000000000000000000000001674 190.0
TLS3_k127_7542996_14 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000004452 202.0
TLS3_k127_7542996_15 Catalyzes the conversion of maleate to fumarate K01799 - 5.2.1.1 0.0000000000000000000000000000000000000000000000000002616 193.0
TLS3_k127_7542996_16 ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000123 170.0
TLS3_k127_7542996_17 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000007521 128.0
TLS3_k127_7542996_18 Putative cyclase - - - 0.0000000000000000000007926 105.0
TLS3_k127_7542996_19 transmembrane transporter activity - - - 0.00000000000496 78.0
TLS3_k127_7542996_2 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 423.0
TLS3_k127_7542996_20 Belongs to the UPF0235 family K09131 - - 0.0000000002631 63.0
TLS3_k127_7542996_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 399.0
TLS3_k127_7542996_4 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 383.0
TLS3_k127_7542996_5 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 379.0
TLS3_k127_7542996_6 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009815 316.0
TLS3_k127_7542996_7 2-methylcitrate dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009998 304.0
TLS3_k127_7542996_8 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 291.0
TLS3_k127_7542996_9 Cyclodeaminase K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000282 289.0
TLS3_k127_7551406_0 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008124 517.0
TLS3_k127_7551406_1 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000002906 223.0
TLS3_k127_7614455_0 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 582.0
TLS3_k127_7614455_1 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 570.0
TLS3_k127_7614455_2 Lipid A 3-O-deacylase (PagL) - - - 0.0000000000000000000000003947 114.0
TLS3_k127_7614455_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000002226 95.0
TLS3_k127_7614455_4 Alcohol dehydrogenase GroES-like domain - - - 0.000000000006835 76.0
TLS3_k127_7614455_5 - - - - 0.000000000009187 75.0
TLS3_k127_7663118_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 567.0
TLS3_k127_7663118_1 TIM-barrel fold metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002271 259.0
TLS3_k127_7663118_2 Phosphomannose isomerase type I K01809,K01840 - 5.3.1.8,5.4.2.8 0.0000000000000000004768 90.0
TLS3_k127_7663118_3 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.00000000000000366 87.0
TLS3_k127_7716860_0 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000003078 208.0
TLS3_k127_7716860_1 nuclease activity - - - 0.0000000000000000000000000000000923 128.0
TLS3_k127_7716860_2 protein conserved in bacteria - - - 0.000000000000000000001081 107.0
TLS3_k127_7716860_3 TIGRFAM looped-hinge helix DNA binding domain, AbrB family - - - 0.00000000000000002687 83.0
TLS3_k127_7716860_4 mRNA binding K07339 - - 0.000009069 47.0
TLS3_k127_7716860_5 Transposase K07491 - - 0.00003134 48.0
TLS3_k127_7743319_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.697e-273 852.0
TLS3_k127_7743319_1 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006646 473.0
TLS3_k127_7743319_2 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 341.0
TLS3_k127_7743319_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 307.0
TLS3_k127_7743319_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000007167 257.0
TLS3_k127_7807412_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1247.0
TLS3_k127_7807412_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 4.522e-200 648.0
TLS3_k127_7807412_2 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 368.0
TLS3_k127_7807412_3 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000008039 245.0
TLS3_k127_7807412_4 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000003027 194.0
TLS3_k127_7807412_5 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000002759 178.0
TLS3_k127_7807412_6 Tetratricopeptide repeat - - - 0.00006586 51.0
TLS3_k127_7854908_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000168 280.0
TLS3_k127_7854908_1 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000003297 195.0
TLS3_k127_7854908_10 Cupin 2, conserved barrel domain protein - - - 0.00001912 52.0
TLS3_k127_7854908_11 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K08234 - 4.4.1.5 0.00002906 52.0
TLS3_k127_7854908_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000007902 188.0
TLS3_k127_7854908_3 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000007004 181.0
TLS3_k127_7854908_4 Amidohydrolase - - - 0.0000000000000000000000000001616 128.0
TLS3_k127_7854908_5 Methyltransferase domain - - - 0.000000000000000000004925 104.0
TLS3_k127_7854908_6 antibiotic catabolic process K13277 - - 0.0000000000000000003167 92.0
TLS3_k127_7854908_8 - - - - 0.00000001716 58.0
TLS3_k127_7854908_9 Belongs to the enoyl-CoA hydratase isomerase family K18383 - 4.1.2.41,4.2.1.101 0.0000001547 53.0
TLS3_k127_7870177_0 OpgC protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009071 424.0
TLS3_k127_7870177_1 NnrS protein K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 350.0
TLS3_k127_7870177_2 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001877 239.0
TLS3_k127_7870177_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000004315 214.0
TLS3_k127_7870177_4 Protein of unknown function (DUF1428) - - - 0.000000000000000000000000000000000000000000000000000000000006764 208.0
TLS3_k127_7870177_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000005326 149.0
TLS3_k127_7870177_6 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.00000000000000000000000000000000000007458 143.0
TLS3_k127_7870177_7 Amidohydrolase family - - - 0.0000000000000000000000000000002099 141.0
TLS3_k127_7894208_0 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001802 272.0
TLS3_k127_7894208_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000001716 155.0
TLS3_k127_7894208_3 SnoaL-like domain - - - 0.000000000000000000000000005248 114.0
TLS3_k127_7894208_4 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000006988 100.0
TLS3_k127_7894208_5 radical SAM domain protein K04069 - 1.97.1.4 0.0000003075 52.0
TLS3_k127_7922109_0 Glycosyl transferase family 21 K03669 - - 4.314e-211 683.0
TLS3_k127_7922109_1 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 500.0
TLS3_k127_7922109_11 PFAM ATP-binding region ATPase domain protein K10819 - 2.7.13.3 0.0002569 51.0
TLS3_k127_7922109_2 Mediates influx of magnesium ions K03284,K16074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 451.0
TLS3_k127_7922109_3 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 291.0
TLS3_k127_7922109_4 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004616 243.0
TLS3_k127_7922109_5 Glyoxalase-like domain K04750 - - 0.0000000000000000000000000000000000000000000000000000003393 197.0
TLS3_k127_7922109_6 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000007243 175.0
TLS3_k127_7922109_7 PFAM FxsA cytoplasmic membrane protein K07113 - - 0.0000000000000000000000000000000001527 139.0
TLS3_k127_7922109_8 TLC ATP/ADP transporter K03301 - - 0.000000000000004828 88.0
TLS3_k127_7922109_9 Prokaryotic N-terminal methylation motif K02456,K02650,K02655 - - 0.00000000000001661 79.0
TLS3_k127_7950265_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 523.0
TLS3_k127_7950265_1 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 467.0
TLS3_k127_7950265_2 TRAP transporter, solute receptor (TAXI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 397.0
TLS3_k127_7950265_3 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.000000000000000000000000000000000000000000000000000004152 208.0
TLS3_k127_7950265_4 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000000000000001659 142.0
TLS3_k127_7982646_0 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 329.0
TLS3_k127_7982646_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 299.0
TLS3_k127_7982646_2 - - - - 0.0000000000000000000000000000000000000007632 156.0
TLS3_k127_7992689_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 2.024e-238 754.0
TLS3_k127_7992689_1 LVIVD repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 381.0
TLS3_k127_7992689_10 ACT domain - - - 0.0000000000000000000000000000000000004912 144.0
TLS3_k127_7992689_11 - - - - 0.000000000000000000000000000000000001892 153.0
TLS3_k127_7992689_12 response regulator K02481 - - 0.000000000000000000001214 101.0
TLS3_k127_7992689_13 Cupin - - - 0.00000000000000002308 87.0
TLS3_k127_7992689_14 PFAM transcription elongation factor GreA GreB K06140 - - 0.00000000000000007085 84.0
TLS3_k127_7992689_15 peptidyl-tyrosine sulfation - - - 0.00000000000003421 81.0
TLS3_k127_7992689_16 Protein of unknown function (DUF3108) - - - 0.0000000000006278 79.0
TLS3_k127_7992689_17 Transcription elongation factor, GreA/GreB, C-term K06140 - - 0.0003133 43.0
TLS3_k127_7992689_18 Glycine-zipper domain - - - 0.0003561 48.0
TLS3_k127_7992689_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 362.0
TLS3_k127_7992689_3 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001951 284.0
TLS3_k127_7992689_4 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000004883 225.0
TLS3_k127_7992689_5 Hydrolase - - - 0.000000000000000000000000000000000000000000000000000000003249 206.0
TLS3_k127_7992689_6 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000000000000000000000000009379 183.0
TLS3_k127_7992689_7 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000004278 183.0
TLS3_k127_7992689_8 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000002684 153.0
TLS3_k127_7992689_9 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000000000000000000000000000000005678 157.0
TLS3_k127_8005058_0 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001411 289.0
TLS3_k127_8005058_1 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008668 285.0
TLS3_k127_8005058_10 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000006109 153.0
TLS3_k127_8005058_11 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000008591 145.0
TLS3_k127_8005058_12 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000001182 151.0
TLS3_k127_8005058_13 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000003212 140.0
TLS3_k127_8005058_14 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000001865 133.0
TLS3_k127_8005058_15 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000001288 123.0
TLS3_k127_8005058_16 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000003995 117.0
TLS3_k127_8005058_17 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000234 110.0
TLS3_k127_8005058_18 ABC transporter substrate binding protein K01989 - - 0.000000000000004289 81.0
TLS3_k127_8005058_19 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00008456 46.0
TLS3_k127_8005058_2 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007723 276.0
TLS3_k127_8005058_20 ABC transporter substrate binding protein K01989 - - 0.0001073 46.0
TLS3_k127_8005058_3 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009978 274.0
TLS3_k127_8005058_4 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007633 263.0
TLS3_k127_8005058_5 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002426 259.0
TLS3_k127_8005058_6 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002481 250.0
TLS3_k127_8005058_7 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000001062 229.0
TLS3_k127_8005058_8 - - - - 0.00000000000000000000000000000000000000000004913 164.0
TLS3_k127_8005058_9 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000001636 161.0
TLS3_k127_8008302_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K00087 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 436.0
TLS3_k127_8011874_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.969e-265 837.0
TLS3_k127_8011874_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 9.569e-219 698.0
TLS3_k127_8011874_10 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 421.0
TLS3_k127_8011874_11 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 423.0
TLS3_k127_8011874_12 Ferrous iron transport protein B K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 417.0
TLS3_k127_8011874_13 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 394.0
TLS3_k127_8011874_14 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 345.0
TLS3_k127_8011874_15 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 349.0
TLS3_k127_8011874_16 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 310.0
TLS3_k127_8011874_17 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 308.0
TLS3_k127_8011874_18 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 339.0
TLS3_k127_8011874_19 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 301.0
TLS3_k127_8011874_2 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009708 505.0
TLS3_k127_8011874_20 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 297.0
TLS3_k127_8011874_21 Sodium:sulfate symporter transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001362 308.0
TLS3_k127_8011874_22 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000001067 265.0
TLS3_k127_8011874_23 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000002422 267.0
TLS3_k127_8011874_24 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000004925 267.0
TLS3_k127_8011874_25 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000001285 263.0
TLS3_k127_8011874_26 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001779 252.0
TLS3_k127_8011874_27 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.00000000000000000000000000000000000000000000000000000000000000000000001002 250.0
TLS3_k127_8011874_28 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003515 240.0
TLS3_k127_8011874_29 KR domain K03366 - 1.1.1.304,1.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000002255 231.0
TLS3_k127_8011874_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 480.0
TLS3_k127_8011874_30 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000087 231.0
TLS3_k127_8011874_31 Von Willebrand factor type A - - - 0.00000000000000000000000000000000000000000000000000000000000009683 228.0
TLS3_k127_8011874_32 PFAM binding-protein-dependent transport systems inner membrane component K02042 - - 0.000000000000000000000000000000000000000000000000000000000006982 218.0
TLS3_k127_8011874_33 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000003388 217.0
TLS3_k127_8011874_34 TIGRFAM phosphate phosphite phosphonate ABC transporters, periplasmic binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000003592 211.0
TLS3_k127_8011874_35 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000001748 193.0
TLS3_k127_8011874_36 Dopa 4,5-dioxygenase family K10253 - - 0.00000000000000000000000000000000000000000001975 164.0
TLS3_k127_8011874_37 carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000000000003092 159.0
TLS3_k127_8011874_38 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000001404 135.0
TLS3_k127_8011874_39 RNA recognition motif - - - 0.00000000000000000000000000000002347 128.0
TLS3_k127_8011874_4 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 505.0
TLS3_k127_8011874_40 Thioesterase superfamily K10806 - - 0.000000000000000000000000000000131 127.0
TLS3_k127_8011874_41 Putative prokaryotic signal transducing protein - - - 0.000000000000000000000000002451 115.0
TLS3_k127_8011874_42 regulation of translation K03530,K05788 - - 0.000000000000000000000000005843 112.0
TLS3_k127_8011874_43 50S ribosomal protein L31 K02909 - - 0.000000000000000000000000009053 113.0
TLS3_k127_8011874_44 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000000003901 107.0
TLS3_k127_8011874_45 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000001401 93.0
TLS3_k127_8011874_46 Tetratricopeptide repeat - - - 0.00000000000002816 83.0
TLS3_k127_8011874_47 - - - - 0.0000000000124 73.0
TLS3_k127_8011874_48 - - - - 0.00001796 58.0
TLS3_k127_8011874_49 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00003749 48.0
TLS3_k127_8011874_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 462.0
TLS3_k127_8011874_6 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 447.0
TLS3_k127_8011874_7 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 426.0
TLS3_k127_8011874_8 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 427.0
TLS3_k127_8011874_9 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 418.0
TLS3_k127_8104780_0 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 488.0
TLS3_k127_8104780_1 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 434.0
TLS3_k127_8104780_2 Elements of external origin K07494 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 417.0
TLS3_k127_8104780_3 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 353.0
TLS3_k127_8104780_4 membrane protein (DUF2254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 299.0
TLS3_k127_8104780_5 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000884 102.0
TLS3_k127_8138305_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 537.0
TLS3_k127_8138305_1 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 477.0
TLS3_k127_8138305_10 PFAM Nucleotidyl transferase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008942 294.0
TLS3_k127_8138305_11 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001131 282.0
TLS3_k127_8138305_12 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001251 275.0
TLS3_k127_8138305_13 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000000000000000000000000785 271.0
TLS3_k127_8138305_14 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000161 267.0
TLS3_k127_8138305_15 MlaA lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000004593 235.0
TLS3_k127_8138305_16 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000377 194.0
TLS3_k127_8138305_17 - - - - 0.00000000000000000000000000000000000000001312 164.0
TLS3_k127_8138305_18 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.000000000000000000000000000007648 121.0
TLS3_k127_8138305_19 - - - - 0.0000000000000000000000000001235 121.0
TLS3_k127_8138305_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 462.0
TLS3_k127_8138305_20 peptidyl-tyrosine sulfation - - - 0.0000000000000000000006078 100.0
TLS3_k127_8138305_22 response regulator receiver - - - 0.000000000000000336 91.0
TLS3_k127_8138305_24 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.000000000587 65.0
TLS3_k127_8138305_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 455.0
TLS3_k127_8138305_4 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 376.0
TLS3_k127_8138305_5 Conserved carboxylase domain K01571 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 384.0
TLS3_k127_8138305_6 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 366.0
TLS3_k127_8138305_7 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 348.0
TLS3_k127_8138305_8 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 337.0
TLS3_k127_8138305_9 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049,K15555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 300.0
TLS3_k127_8180125_0 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 477.0
TLS3_k127_8180125_1 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 328.0
TLS3_k127_8180125_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 311.0
TLS3_k127_8186053_0 MacB-like periplasmic core domain K02004 - - 5.633e-215 695.0
TLS3_k127_8186053_1 Tripartite tricarboxylate transporter TctA family K07793 - - 2.498e-213 674.0
TLS3_k127_8186053_10 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000001939 204.0
TLS3_k127_8186053_11 Belongs to the mandelate racemase muconate lactonizing enzyme family K01856 - 5.5.1.1 0.00000000000000000000000000000000000000000000001128 185.0
TLS3_k127_8186053_12 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000008362 164.0
TLS3_k127_8186053_13 thiamine-containing compound biosynthetic process K02051,K15551,K15556 - - 0.000000000000000000000000000000000000000003039 168.0
TLS3_k127_8186053_14 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000002312 156.0
TLS3_k127_8186053_15 Catalyzes the conversion of maleate to fumarate K01799 - 5.2.1.1 0.000000000000000000000000000000002694 138.0
TLS3_k127_8186053_16 Transcriptional - - - 0.000000000000000000000000000000771 126.0
TLS3_k127_8186053_17 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000009258 124.0
TLS3_k127_8186053_18 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000002497 113.0
TLS3_k127_8186053_19 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000000000000000000005491 105.0
TLS3_k127_8186053_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 578.0
TLS3_k127_8186053_20 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000006065 108.0
TLS3_k127_8186053_21 cellulase activity K12567 - 2.7.11.1 0.000000002624 70.0
TLS3_k127_8186053_22 - - - - 0.00001687 55.0
TLS3_k127_8186053_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 495.0
TLS3_k127_8186053_4 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 432.0
TLS3_k127_8186053_5 protein conserved in bacteria K07795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 341.0
TLS3_k127_8186053_6 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 297.0
TLS3_k127_8186053_7 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005508 281.0
TLS3_k127_8186053_8 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000008536 249.0
TLS3_k127_8186053_9 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000001607 202.0
TLS3_k127_8191322_0 PEP-utilising enzyme, N-terminal K08484 - 2.7.3.9 1.333e-209 677.0
TLS3_k127_8191322_1 ABC-type Fe3 transport system permease component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 420.0
TLS3_k127_8191322_10 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000004148 207.0
TLS3_k127_8191322_11 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000003119 200.0
TLS3_k127_8191322_12 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000003708 192.0
TLS3_k127_8191322_14 Isochorismatase family K09020 - 3.5.1.110 0.0000000000000000000000000000000000000000000000002771 183.0
TLS3_k127_8191322_15 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000001581 171.0
TLS3_k127_8191322_17 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000008415 144.0
TLS3_k127_8191322_18 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000007729 134.0
TLS3_k127_8191322_19 Domain of unknown function (DUF4263) - - - 0.00000000000000000000001684 106.0
TLS3_k127_8191322_2 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 411.0
TLS3_k127_8191322_20 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000004308 104.0
TLS3_k127_8191322_21 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000000000005181 108.0
TLS3_k127_8191322_22 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 0.0000000000001194 75.0
TLS3_k127_8191322_23 Nitrate ABC transporter substrate-binding protein K02051 - - 0.0000000000004163 80.0
TLS3_k127_8191322_24 - - - - 0.0000000000006763 77.0
TLS3_k127_8191322_26 - - - - 0.000002684 51.0
TLS3_k127_8191322_27 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic - - - 0.00001109 55.0
TLS3_k127_8191322_3 NADH dehydrogenase K00335,K18331 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 359.0
TLS3_k127_8191322_4 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 326.0
TLS3_k127_8191322_5 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001921 279.0
TLS3_k127_8191322_6 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003851 262.0
TLS3_k127_8191322_7 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000002157 239.0
TLS3_k127_8191322_8 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.000000000000000000000000000000000000000000000000000000000000000009223 238.0
TLS3_k127_8191322_9 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000004742 226.0
TLS3_k127_8204272_0 Polysaccharide biosynthesis protein K01710,K15894,K15912,K19421 GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192 4.2.1.115,4.2.1.135,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 567.0
TLS3_k127_8204272_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000132 145.0
TLS3_k127_8205338_0 major pilin protein fima - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 298.0
TLS3_k127_8205338_1 PFAM TM2 domain - - - 0.00000000000000000000000000001872 123.0
TLS3_k127_8205338_2 Protein of unknown function (DUF2752) - - - 0.00000000000000000000005738 104.0
TLS3_k127_8205338_3 - - - - 0.00000000000000002149 89.0
TLS3_k127_8205338_4 response to antibiotic - - - 0.00000000000000002792 87.0
TLS3_k127_8237706_0 Domain of unknown function (DUF2172) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 600.0
TLS3_k127_8237706_1 Polysaccharide biosynthesis protein K01709 - 4.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 466.0
TLS3_k127_8237706_2 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K00067,K01790 - 1.1.1.133,5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000005943 248.0
TLS3_k127_8237706_3 Histidine kinase K13040 - 2.7.13.3 0.0000000000000000000000005611 107.0
TLS3_k127_8253346_0 PFAM Cation transporter K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 338.0
TLS3_k127_8253346_1 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000001176 229.0
TLS3_k127_8253346_2 PFAM TrkA-N domain protein K03499 - - 0.00000000000000000000000000000000000000001775 160.0
TLS3_k127_8253346_3 RNA recognition motif - - - 0.00000000000000000000000000000000006871 135.0
TLS3_k127_8253346_4 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000001887 115.0
TLS3_k127_8253346_5 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0005209 50.0
TLS3_k127_8285546_0 alpha-methylacyl-CoA racemase activity K18703 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0008410,GO:0016740,GO:0016782,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0047369 2.8.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 460.0
TLS3_k127_8285546_1 Acetolactate synthase K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 325.0
TLS3_k127_8285546_10 NMT1-like family K02051 - - 0.00000000000000002355 94.0
TLS3_k127_8285546_11 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000008682 53.0
TLS3_k127_8285546_2 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000001559 205.0
TLS3_k127_8285546_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000003798 194.0
TLS3_k127_8285546_4 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000337 144.0
TLS3_k127_8285546_5 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000001664 134.0
TLS3_k127_8285546_6 Transcriptional regulator - - - 0.000000000000000000000000000000001944 141.0
TLS3_k127_8285546_7 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000000000000000000003529 135.0
TLS3_k127_8285546_8 Dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000144 117.0
TLS3_k127_8285546_9 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000000007344 99.0
TLS3_k127_8323737_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008023 255.0
TLS3_k127_8323737_1 4'-phosphopantetheinyl transferase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001122 217.0
TLS3_k127_834733_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 428.0
TLS3_k127_834733_1 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 391.0
TLS3_k127_834733_10 Excisionase - - - 0.00000007498 60.0
TLS3_k127_834733_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 385.0
TLS3_k127_834733_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000003493 265.0
TLS3_k127_834733_4 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000002486 237.0
TLS3_k127_834733_5 amidohydrolase K03392,K07045 - 4.1.1.45 0.00000000000000000000000000000000000000000000008792 180.0
TLS3_k127_834733_6 PFAM small multidrug resistance protein K11741 - - 0.000000000000000000000000000000000000000000000653 167.0
TLS3_k127_834733_7 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000008634 140.0
TLS3_k127_834733_8 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000001238 105.0
TLS3_k127_834733_9 Polymer-forming cytoskeletal - - - 0.00000002568 61.0
TLS3_k127_8390799_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005926 522.0
TLS3_k127_8390799_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 350.0
TLS3_k127_8390799_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000006752 209.0
TLS3_k127_8390799_3 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000008074 179.0
TLS3_k127_8390799_4 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000004247 160.0
TLS3_k127_8390799_5 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000006705 158.0
TLS3_k127_8390799_6 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000008458 143.0
TLS3_k127_8390799_7 epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000002498 138.0
TLS3_k127_8390799_8 NMT1-like family - - - 0.0000000000000000003273 99.0
TLS3_k127_8417948_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 336.0
TLS3_k127_8417948_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000381 308.0
TLS3_k127_8417948_2 PFAM 2-nitropropane dioxygenase NPD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 292.0
TLS3_k127_8417948_3 conserved protein, contains double-stranded beta-helix domain - - - 0.00000000000000000000000000000000000000000000000004116 186.0
TLS3_k127_8417948_4 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000004746 186.0
TLS3_k127_8417948_5 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000005258 184.0
TLS3_k127_8417948_6 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000004706 183.0
TLS3_k127_8417948_7 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000001642 178.0
TLS3_k127_8427704_0 TIM-barrel fold metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004319 277.0
TLS3_k127_8427704_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001347 239.0
TLS3_k127_8427704_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001461 237.0
TLS3_k127_8427704_3 4,5-dihydroxyphthalate decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000005367 237.0
TLS3_k127_8427704_4 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000001415 179.0
TLS3_k127_8427704_5 Protein of unknown function, DUF - - - 0.0000000000000000000000000000000000003211 142.0
TLS3_k127_8427704_6 - - - - 0.0000000000000000000000000000009818 131.0
TLS3_k127_8484458_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 1.315e-194 617.0
TLS3_k127_8484458_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001933 270.0
TLS3_k127_8484458_2 Mo-molybdopterin cofactor metabolic process K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000142 196.0
TLS3_k127_8484458_3 MoaE protein K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000007695 160.0
TLS3_k127_8484458_4 PFAM GYD family protein - - - 0.000000000000000000000000003871 114.0
TLS3_k127_8484458_5 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K21142 - 2.8.1.12 0.00000000000001022 80.0
TLS3_k127_8498789_0 Cytochrome c - - - 9.241e-218 706.0
TLS3_k127_8498789_1 Cytochrome b(N-terminal)/b6/petB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 424.0
TLS3_k127_8498789_2 'glutamate synthase K00528,K03388 - 1.18.1.2,1.19.1.1,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 383.0
TLS3_k127_8498789_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 326.0
TLS3_k127_8498789_4 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005438 244.0
TLS3_k127_8498789_5 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000001124 213.0
TLS3_k127_8498789_6 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000001373 124.0
TLS3_k127_8498789_7 Class ii aldolase K01628 - 4.1.2.17 0.000000000000000000000000000004382 128.0
TLS3_k127_8498789_8 - - - - 0.0000000000003406 78.0
TLS3_k127_8498789_9 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00001483 47.0
TLS3_k127_8503604_0 Helicase ATP-dependent domain protein K03579 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 311.0
TLS3_k127_8503604_1 Protein of unknown function (DUF1722) K13281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005941 285.0
TLS3_k127_8503604_2 - - - - 0.00000000000000000000002295 100.0
TLS3_k127_8503604_3 Transglycosylase SLT domain - - - 0.000001181 53.0
TLS3_k127_8526708_0 Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc K00975 - 2.7.7.27 4.506e-216 676.0
TLS3_k127_8526708_1 Tripartite tricarboxylate transporter TctA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 609.0
TLS3_k127_8526708_10 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000001094 68.0
TLS3_k127_8526708_11 Isochorismatase family - - - 0.00000000003281 69.0
TLS3_k127_8526708_12 - - - - 0.000000001759 66.0
TLS3_k127_8526708_13 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.00000003327 58.0
TLS3_k127_8526708_14 ABC transporter K02003 - - 0.0001283 47.0
TLS3_k127_8526708_15 Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system K15555 - - 0.0003405 46.0
TLS3_k127_8526708_2 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 509.0
TLS3_k127_8526708_3 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 291.0
TLS3_k127_8526708_4 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005873 292.0
TLS3_k127_8526708_5 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000006175 214.0
TLS3_k127_8526708_6 polyketide cyclase - - - 0.000000000000000000000000000000000004593 141.0
TLS3_k127_8526708_7 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000000000001047 144.0
TLS3_k127_8526708_8 EamA-like transporter family - - - 0.000000000000000000000000000000001941 140.0
TLS3_k127_8526708_9 Cupin domain - - - 0.00000000000005152 77.0
TLS3_k127_8555012_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 342.0
TLS3_k127_8555012_1 - - - - 0.000000000000000000007587 105.0
TLS3_k127_8577113_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls - - - 0.000000000000000000000000000000000000000000000000005008 198.0
TLS3_k127_8577113_1 Asp/Glu/Hydantoin racemase K01799 - 5.2.1.1 0.000000000000000000000000000000000000000000002265 173.0
TLS3_k127_900405_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 1.942e-223 700.0
TLS3_k127_900405_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 462.0
TLS3_k127_900405_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 415.0
TLS3_k127_900405_3 cytochrome c nitrite reductase K15876 - - 0.00000000000000000000000000000000000000000000000008394 182.0
TLS3_k127_900405_4 BON domain - - - 0.000000000000000000001333 99.0
TLS3_k127_904293_0 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009341 316.0
TLS3_k127_904293_1 Carboxylesterase family K01432 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000339 256.0
TLS3_k127_906766_0 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 456.0
TLS3_k127_906766_1 Protein of unknown function (DUF1207) - - - 0.000000000000000000000000000000000000000000003984 174.0
TLS3_k127_910632_0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 374.0
TLS3_k127_910632_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001652 264.0
TLS3_k127_910632_2 PFAM Transposase DDE domain - - - 0.00001506 47.0
TLS3_k127_931531_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005517 284.0
TLS3_k127_931531_1 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000008475 241.0
TLS3_k127_931531_2 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000001276 242.0
TLS3_k127_931531_3 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000001209 172.0
TLS3_k127_931531_4 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000007573 149.0
TLS3_k127_931531_5 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000000004645 128.0
TLS3_k127_931531_6 Belongs to the BolA IbaG family - - - 0.000000000000000000000000001066 113.0
TLS3_k127_931531_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000009404 106.0
TLS3_k127_931531_8 PFAM CAAX amino terminal protease family K07052 - - 0.0000004637 59.0
TLS3_k127_931531_9 Alkyl hydroperoxide reductase - - - 0.0000009454 51.0
TLS3_k127_947719_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 613.0
TLS3_k127_947719_1 Aminotransferase class-V K00830,K00839 GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000927 447.0
TLS3_k127_947719_10 Pfam:AmoA K07120 - - 0.0000000000000000000000000000000000000000000000000000000000001582 227.0
TLS3_k127_947719_11 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000003306 211.0
TLS3_k127_947719_12 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000002038 208.0
TLS3_k127_947719_13 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000003038 203.0
TLS3_k127_947719_14 Fumarylacetoacetate (FAA) hydrolase family K05921 - 4.1.1.68 0.00000000000000000000000000000000000000000000000000004899 198.0
TLS3_k127_947719_15 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000001336 198.0
TLS3_k127_947719_16 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000001993 195.0
TLS3_k127_947719_17 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000004092 183.0
TLS3_k127_947719_18 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000008542 188.0
TLS3_k127_947719_19 Protein of unknown function (DUF456) K09793 - - 0.00000000000000000000000000000000000000000000000508 181.0
TLS3_k127_947719_2 protein catabolic process K03420,K13525,K17681 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 372.0
TLS3_k127_947719_20 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000005575 175.0
TLS3_k127_947719_21 Asp/Glu/Hydantoin racemase K01799 - 5.2.1.1 0.00000000000000000000000000000000000000005087 161.0
TLS3_k127_947719_22 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000001305 142.0
TLS3_k127_947719_23 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000006988 146.0
TLS3_k127_947719_25 NMT1-like family K07080 - - 0.0000000000000000000000001094 119.0
TLS3_k127_947719_26 Integral membrane protein TerC family - - - 0.000000000000000000000001148 108.0
TLS3_k127_947719_27 Methyltransferase small domain - - - 0.00000000000000000003198 98.0
TLS3_k127_947719_28 - - - - 0.00000000000000000004218 91.0
TLS3_k127_947719_29 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.000000000000000243 89.0
TLS3_k127_947719_3 Methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 372.0
TLS3_k127_947719_30 - - - - 0.00000000000007962 77.0
TLS3_k127_947719_31 Serine aminopeptidase, S33 - - - 0.0000000000001644 81.0
TLS3_k127_947719_32 Cupin 2, conserved barrel domain protein - - - 0.000000001611 63.0
TLS3_k127_947719_4 Oxidoreductase molybdopterin binding K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 361.0
TLS3_k127_947719_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001538 269.0
TLS3_k127_947719_6 SBF-like CPA transporter family (DUF4137) K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001247 265.0
TLS3_k127_947719_7 Uncharacterized conserved protein (COG2071) K09166 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003947 259.0
TLS3_k127_947719_8 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000005773 257.0
TLS3_k127_947719_9 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000009477 228.0
TLS3_k127_962736_0 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000008397 249.0
TLS3_k127_962736_1 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000003482 211.0
TLS3_k127_962736_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000001425 114.0
TLS3_k127_985780_0 Transporter K12942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 561.0
TLS3_k127_985780_1 UPF0365 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 498.0
TLS3_k127_985780_2 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 437.0
TLS3_k127_985780_3 COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 405.0
TLS3_k127_985780_4 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 314.0
TLS3_k127_985780_5 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000138 198.0
TLS3_k127_985780_6 - - - - 0.000000000000009874 79.0