logo

Overview

ID MAG04063
Name TLS3_bin.52
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Gallionellaceae
Genus Gallionella
Species
Assembly information
Completeness (%) 84.99
Contamination (%) 1.24
GC content (%) 59.0
N50 (bp) 12,493
Genome size (bp) 2,394,740

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2368

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1037197_0 FtsX-like permease family K02004 - - 0.0 1110.0
TLS3_k127_1037197_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 3.595e-268 839.0
TLS3_k127_1037197_10 Glycine cleavage system K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 331.0
TLS3_k127_1037197_11 lipid catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007791 332.0
TLS3_k127_1037197_12 TIGRFAM yecA family protein K07039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 323.0
TLS3_k127_1037197_13 PFAM ABC transporter related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009758 311.0
TLS3_k127_1037197_14 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 291.0
TLS3_k127_1037197_15 Thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008682 280.0
TLS3_k127_1037197_16 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007613 249.0
TLS3_k127_1037197_17 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000001068 220.0
TLS3_k127_1037197_18 Putative Fe-S cluster - - - 0.000000000000000000000000000000000000000000000000000000000005061 216.0
TLS3_k127_1037197_19 - - - - 0.0000000000000000000009769 101.0
TLS3_k127_1037197_2 Sugar (and other) transporter - - - 6.283e-229 717.0
TLS3_k127_1037197_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 553.0
TLS3_k127_1037197_4 PFAM Sodium calcium exchanger membrane region K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 519.0
TLS3_k127_1037197_5 HpcH/HpaI aldolase/citrate lyase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 511.0
TLS3_k127_1037197_6 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 481.0
TLS3_k127_1037197_7 TIGRFAM DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008366 482.0
TLS3_k127_1037197_8 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 460.0
TLS3_k127_1037197_9 PFAM cobalamin synthesis protein P47K - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 344.0
TLS3_k127_1048494_0 Predicted membrane protein (DUF2157) - - - 7.264e-200 629.0
TLS3_k127_1048494_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 593.0
TLS3_k127_1048494_10 Protein of unknown function (DUF2442) - - - 0.0000000003452 63.0
TLS3_k127_1048494_2 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 366.0
TLS3_k127_1048494_3 TIGRFAM cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 356.0
TLS3_k127_1048494_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 332.0
TLS3_k127_1048494_5 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003881 270.0
TLS3_k127_1048494_6 UPF0056 inner membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001362 262.0
TLS3_k127_1048494_7 KTSC domain - - - 0.0000000000000000000000000000000000000000007183 158.0
TLS3_k127_1048494_8 Domain of unknown function (DUF1840) - - - 0.0000000000000000000004288 96.0
TLS3_k127_1048494_9 Flagellar regulator YcgR - - - 0.00000000000009885 81.0
TLS3_k127_1096782_0 glycosyl - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 551.0
TLS3_k127_1096782_1 Vitamin k epoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 544.0
TLS3_k127_1096782_10 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000004622 109.0
TLS3_k127_1096782_11 Post-segregation antitoxin CcdA K19164 - - 0.000000000000000005787 86.0
TLS3_k127_1096782_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 436.0
TLS3_k127_1096782_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 412.0
TLS3_k127_1096782_4 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008744 375.0
TLS3_k127_1096782_5 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000000000000000000000000000002136 157.0
TLS3_k127_1096782_6 CcdB protein K19163 - - 0.0000000000000000000000000000000000000001975 152.0
TLS3_k127_1096782_7 Iron-sulfur cluster assembly protein - - - 0.0000000000000000000000000000000000001737 147.0
TLS3_k127_1096782_8 Indole-3-glycerol phosphate synthase K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.0000000000000000000000000000000000004626 141.0
TLS3_k127_1107967_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.0 1117.0
TLS3_k127_1107967_1 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.0 1010.0
TLS3_k127_1107967_10 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000002177 239.0
TLS3_k127_1107967_11 transport system periplasmic component K01989 - - 0.00000000000000000000000000000000000000000000000000005255 201.0
TLS3_k127_1107967_12 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000006026 172.0
TLS3_k127_1107967_13 alpha-glucan phosphorylase K00688 - 2.4.1.1 0.00001218 54.0
TLS3_k127_1107967_2 TonB dependent receptor K02014 - - 4.837e-200 650.0
TLS3_k127_1107967_3 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 587.0
TLS3_k127_1107967_4 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 451.0
TLS3_k127_1107967_5 PFAM TonB-dependent receptor plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 467.0
TLS3_k127_1107967_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 418.0
TLS3_k127_1107967_7 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 415.0
TLS3_k127_1107967_8 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 331.0
TLS3_k127_1107967_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 313.0
TLS3_k127_1155519_0 Polyphosphate kinase 2 (PPK2) - - - 1.123e-294 908.0
TLS3_k127_1155519_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 8.202e-230 714.0
TLS3_k127_1155519_2 PFAM EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 559.0
TLS3_k127_1155519_3 Phosphoglycerate mutase family K08296 - - 0.00000000000000000000000000000000000000000000000000000666 193.0
TLS3_k127_1155519_4 - - - - 0.000000000000000000002481 97.0
TLS3_k127_1171960_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0 1000.0
TLS3_k127_1171960_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 5.099e-258 803.0
TLS3_k127_1171960_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 602.0
TLS3_k127_1171960_3 AAA domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 393.0
TLS3_k127_1171960_4 PFAM import inner membrane translocase subunit Tim44 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 364.0
TLS3_k127_1171960_5 protein conserved in bacteria K03690 - - 0.0000000000000000000000000000000000000000000000000000000006005 207.0
TLS3_k127_1203517_0 Class II Aldolase and Adducin N-terminal domain - - - 1.55e-257 809.0
TLS3_k127_1203517_1 MacB-like periplasmic core domain K02004 - - 4.799e-199 627.0
TLS3_k127_1203517_10 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 288.0
TLS3_k127_1203517_11 PFAM porin Gram-negative type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002687 257.0
TLS3_k127_1203517_12 Histidine Phosphotransfer domain - - - 0.00000000000000000000000000000000000000000124 166.0
TLS3_k127_1203517_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 539.0
TLS3_k127_1203517_3 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 541.0
TLS3_k127_1203517_4 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 542.0
TLS3_k127_1203517_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 509.0
TLS3_k127_1203517_6 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 493.0
TLS3_k127_1203517_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 483.0
TLS3_k127_1203517_8 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 362.0
TLS3_k127_1203517_9 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 322.0
TLS3_k127_1206122_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 533.0
TLS3_k127_1206122_1 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000000000000000001538 269.0
TLS3_k127_1206122_2 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000006926 197.0
TLS3_k127_1236675_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1065.0
TLS3_k127_1236675_1 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.00000000000000000000000000000000000002048 146.0
TLS3_k127_1289590_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 1.52e-214 678.0
TLS3_k127_1289590_1 EAL domain K21024 - 3.1.4.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 469.0
TLS3_k127_1289590_2 S4 RNA-binding domain K06182 - 5.4.99.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 427.0
TLS3_k127_1289590_3 Transporter associated domain K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000111 239.0
TLS3_k127_1289590_4 membrane - - - 0.000000000000000000000000000000000000000000002969 164.0
TLS3_k127_1289590_5 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.0000000000000000000000000000005464 123.0
TLS3_k127_1312033_0 Belongs to the DEAD box helicase family K05591 GO:0000339,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003729,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006412,GO:0006413,GO:0006518,GO:0006725,GO:0006807,GO:0008026,GO:0008135,GO:0008150,GO:0008152,GO:0008186,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0010501,GO:0016070,GO:0016281,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0042623,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0060255,GO:0065007,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 3.6.4.13 3.807e-256 794.0
TLS3_k127_1312033_1 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645,K13935,K15355 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 524.0
TLS3_k127_1312033_2 KR domain K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 430.0
TLS3_k127_1312033_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001979 248.0
TLS3_k127_1312033_4 - - - - 0.00000000000000000000000000000000000000000001122 168.0
TLS3_k127_1312033_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000007088 79.0
TLS3_k127_1319436_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0 1054.0
TLS3_k127_1319436_1 Diguanylate cyclase - - - 3.189e-269 857.0
TLS3_k127_1319436_2 PFAM DEAD DEAH box helicase domain protein - - - 2.702e-212 668.0
TLS3_k127_1319436_3 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 550.0
TLS3_k127_1319436_4 Met-10+ like-protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 347.0
TLS3_k127_1319436_5 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 330.0
TLS3_k127_1319436_6 PFAM Protein-tyrosine phosphatase, low molecular weight K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000003566 243.0
TLS3_k127_1319436_7 signal transduction protein containing EAL and modified HD-GYP - - - 0.00000000000000000000000000000000000000000000007579 183.0
TLS3_k127_1322405_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0 1000.0
TLS3_k127_1322405_1 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 7.855e-307 946.0
TLS3_k127_1322405_10 Type III restriction - - - 0.000000000000000000000002796 102.0
TLS3_k127_1322405_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 7.21e-280 865.0
TLS3_k127_1322405_3 Type III restriction enzyme, res subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 594.0
TLS3_k127_1322405_4 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 493.0
TLS3_k127_1322405_5 Dead deah box helicase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 445.0
TLS3_k127_1322405_6 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 394.0
TLS3_k127_1322405_7 PIN domain - - - 0.0000000000000000000000000000000000000000000000000001617 188.0
TLS3_k127_1322405_8 TRANSCRIPTIONal - - - 0.000000000000000000000000000000000003147 139.0
TLS3_k127_1322405_9 toxin-antitoxin pair type II binding K19156 GO:0001558,GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0040008,GO:0042802,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000001503 126.0
TLS3_k127_1428607_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1341.0
TLS3_k127_1428607_1 SurA N-terminal domain K03770 - 5.2.1.8 3.016e-241 761.0
TLS3_k127_1428607_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000002088 131.0
TLS3_k127_1428607_11 - - - - 0.0000000000000004419 85.0
TLS3_k127_1428607_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 9.185e-236 733.0
TLS3_k127_1428607_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 601.0
TLS3_k127_1428607_4 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 511.0
TLS3_k127_1428607_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 372.0
TLS3_k127_1428607_6 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 346.0
TLS3_k127_1428607_7 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000005901 248.0
TLS3_k127_1428607_8 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000000000000000000000000005775 209.0
TLS3_k127_1428607_9 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000000000000000000000002714 147.0
TLS3_k127_143197_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 484.0
TLS3_k127_143197_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009439 292.0
TLS3_k127_1433786_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007664 545.0
TLS3_k127_150602_0 PFAM Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 391.0
TLS3_k127_150602_1 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005048 287.0
TLS3_k127_150602_10 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000002752 85.0
TLS3_k127_150602_11 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.0000000001797 67.0
TLS3_k127_150602_2 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001132 259.0
TLS3_k127_150602_3 chemotaxis K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000001878 248.0
TLS3_k127_150602_4 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039 - - 0.000000000000000000000000000000000000000000000000000005863 190.0
TLS3_k127_150602_5 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000001273 182.0
TLS3_k127_150602_6 PFAM ADP-ribosylation Crystallin J1 - - - 0.00000000000000000000000000000000000000000004681 166.0
TLS3_k127_150602_7 MazG-like family - - - 0.000000000000000000000000000000000000000005533 158.0
TLS3_k127_150602_8 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000171 166.0
TLS3_k127_150602_9 VanZ like family - - - 0.00000000000000000000002277 104.0
TLS3_k127_1592273_0 Abc transporter K06158 - - 0.0 1069.0
TLS3_k127_1592273_1 glucan 1,4-alpha-glucosidase activity - - - 6.669e-267 829.0
TLS3_k127_1592273_10 Putative prokaryotic signal transducing protein - - - 0.000000000000000000000000000000000000009608 148.0
TLS3_k127_1592273_11 Diguanylate cyclase K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000001159 125.0
TLS3_k127_1592273_12 PAS domain containing protein - - - 0.0000000000000000002318 99.0
TLS3_k127_1592273_2 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 567.0
TLS3_k127_1592273_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 357.0
TLS3_k127_1592273_4 3'-5' exonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 335.0
TLS3_k127_1592273_5 signal transduction protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 313.0
TLS3_k127_1592273_6 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000001398 261.0
TLS3_k127_1592273_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000303 252.0
TLS3_k127_1592273_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000183 207.0
TLS3_k127_1592273_9 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000001825 206.0
TLS3_k127_1656672_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 5.727e-198 622.0
TLS3_k127_1656672_1 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 514.0
TLS3_k127_1656672_10 - - - - 0.0000000000000000000000000000008541 139.0
TLS3_k127_1656672_11 - - - - 0.0000000001508 68.0
TLS3_k127_1656672_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 511.0
TLS3_k127_1656672_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 452.0
TLS3_k127_1656672_4 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008188 405.0
TLS3_k127_1656672_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 324.0
TLS3_k127_1656672_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 287.0
TLS3_k127_1656672_7 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003525 271.0
TLS3_k127_1656672_8 Copper resistance protein D - - - 0.000000000000000000000000000000000000000000000000000000000000000000001463 239.0
TLS3_k127_1656672_9 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.0000000000000000000000000000000000000000004332 159.0
TLS3_k127_1692112_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 2.059e-224 702.0
TLS3_k127_1692112_1 psiF repeat - - - 0.0000000008919 62.0
TLS3_k127_1744945_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic domain K01886 - 6.1.1.18 0.0 1080.0
TLS3_k127_1744945_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 4.694e-264 818.0
TLS3_k127_1744945_2 general secretion pathway protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001401 252.0
TLS3_k127_1744945_3 membrane - - - 0.0000000000000000000000000000000000000000000000000000001032 197.0
TLS3_k127_1744945_4 - - - - 0.0000000000000000000000000000000000000000000000000256 193.0
TLS3_k127_1744945_5 - - - - 0.00000000000000000000000000000000000000000000000003569 185.0
TLS3_k127_1744945_6 - - - - 0.000000000000000001402 91.0
TLS3_k127_1744945_7 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.000003043 49.0
TLS3_k127_1748850_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1124.0
TLS3_k127_1748850_1 PFAM AICARFT IMPCHase bienzyme formylation region K00602 - 2.1.2.3,3.5.4.10 6.759e-307 944.0
TLS3_k127_1748850_10 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 381.0
TLS3_k127_1748850_11 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 340.0
TLS3_k127_1748850_12 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 291.0
TLS3_k127_1748850_13 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007631 284.0
TLS3_k127_1748850_14 4fe-4s ferredoxin, iron-sulfur binding - - - 0.000000000000000000000000000000000000000000000000000000000000001884 234.0
TLS3_k127_1748850_15 Gram-negative porin - - - 0.000000000000000000000000000000000000000000000004889 186.0
TLS3_k127_1748850_16 protein complex oligomerization - GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006928,GO:0006950,GO:0006974,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0033554,GO:0040011,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0071944,GO:0071973,GO:0071978,GO:0097588,GO:0098552,GO:0098562 - 0.00000000000000000000000000000000006625 145.0
TLS3_k127_1748850_17 TIGRFAM flagellar hook-basal body complex subunit FliE K02408 - - 0.000000000000000000000000000000001712 137.0
TLS3_k127_1748850_18 Bacterial regulatory protein, Fis family K03557 - - 0.000000000000000000000000000000008683 128.0
TLS3_k127_1748850_19 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000000004955 135.0
TLS3_k127_1748850_2 PFAM Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain K01945 - 6.3.4.13 3.186e-247 767.0
TLS3_k127_1748850_3 The M ring may be actively involved in energy transduction K02409 - - 8.281e-230 722.0
TLS3_k127_1748850_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 568.0
TLS3_k127_1748850_5 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 533.0
TLS3_k127_1748850_6 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007196 471.0
TLS3_k127_1748850_7 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 443.0
TLS3_k127_1748850_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 426.0
TLS3_k127_1748850_9 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009554 411.0
TLS3_k127_1758901_0 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000002128 222.0
TLS3_k127_1758901_1 metal-binding protein - - - 0.000000000000000000000000000000000000000000000000000001521 199.0
TLS3_k127_1758901_2 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000007643 130.0
TLS3_k127_1843872_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 604.0
TLS3_k127_1843872_1 PhoH-like phosphate starvation-inducible protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 451.0
TLS3_k127_1843872_2 Transporter associated domain K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005772 294.0
TLS3_k127_1843872_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000000000000000000000000004107 232.0
TLS3_k127_18931_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.874e-266 822.0
TLS3_k127_18931_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 504.0
TLS3_k127_18931_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 417.0
TLS3_k127_190420_0 Peptidase dimerisation domain K01270 - - 2.676e-233 729.0
TLS3_k127_190420_1 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 582.0
TLS3_k127_190420_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 488.0
TLS3_k127_190420_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 445.0
TLS3_k127_190420_4 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000000000000000000233 199.0
TLS3_k127_190420_5 - - - - 0.0000000000000000000000000000000000005328 142.0
TLS3_k127_190420_6 - - - - 0.0000000000000000000000001043 111.0
TLS3_k127_190420_8 - - - - 0.0000000000001536 76.0
TLS3_k127_190420_9 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009420,GO:0009421,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - 0.000007082 57.0
TLS3_k127_1938851_0 Metal-dependent hydrolase HDOD - - - 1.869e-249 792.0
TLS3_k127_1938851_1 Metal-dependent hydrolase HDOD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 441.0
TLS3_k127_1938851_2 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008338 273.0
TLS3_k127_1938851_3 Transcriptional regulator, Crp Fnr family - - - 0.0000000000000000000000000000000000003033 145.0
TLS3_k127_1938851_4 Tautomerase enzyme K01821 - 5.3.2.6 0.00000000000000000000000001349 109.0
TLS3_k127_1938851_5 Tautomerase enzyme K01821 - 5.3.2.6 0.0000001056 53.0
TLS3_k127_1943526_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.651e-319 988.0
TLS3_k127_1943526_1 RNB K01147 - 3.1.13.1 1.698e-307 954.0
TLS3_k127_1943526_10 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 324.0
TLS3_k127_1943526_11 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004811 279.0
TLS3_k127_1943526_12 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000008181 208.0
TLS3_k127_1943526_13 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000001593 204.0
TLS3_k127_1943526_14 Frataxin-like domain K06202 - - 0.000000000000000000000000000000000000000001067 158.0
TLS3_k127_1943526_15 PFAM cytochrome c class I K08738 - - 0.00000000000000000000000000000000000002809 145.0
TLS3_k127_1943526_16 Cytochrome C oxidase, cbb3-type, subunit III K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000002356 125.0
TLS3_k127_1943526_17 Cytochrome c K08738 - - 0.00000000000000000000002112 108.0
TLS3_k127_1943526_18 Cytochrome c K08738 - - 0.000000000000003831 83.0
TLS3_k127_1943526_19 Domain in histone families 1 and 5 K11275 - - 0.00003051 52.0
TLS3_k127_1943526_2 MgtE intracellular N domain K06213 - - 5.977e-237 740.0
TLS3_k127_1943526_3 SMART PAS domain containing protein - - - 7.143e-235 769.0
TLS3_k127_1943526_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 3.937e-216 677.0
TLS3_k127_1943526_5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007138 541.0
TLS3_k127_1943526_6 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 467.0
TLS3_k127_1943526_7 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006787 402.0
TLS3_k127_1943526_8 TonB C terminal K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 377.0
TLS3_k127_1943526_9 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 336.0
TLS3_k127_1952277_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 531.0
TLS3_k127_1952277_1 Type I GTP cyclohydrolase folE2 K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 469.0
TLS3_k127_1952277_2 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 350.0
TLS3_k127_1984951_0 Belongs to the flagella basal body rod proteins family K02396 - - 2.937e-221 707.0
TLS3_k127_1984951_1 PFAM H transporting two-sector ATPase alpha beta subunit central region K02412 - 3.6.3.14 6.077e-203 640.0
TLS3_k127_1984951_10 PFAM MotA TolQ ExbB proton channel K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 370.0
TLS3_k127_1984951_11 TIGRFAM flagellar rod assembly protein muramidase FlgJ K02395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006997 375.0
TLS3_k127_1984951_12 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 364.0
TLS3_k127_1984951_13 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 338.0
TLS3_k127_1984951_14 Bacterial export proteins, family 1 K02421 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 340.0
TLS3_k127_1984951_15 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 309.0
TLS3_k127_1984951_16 Cellulose biosynthesis protein BcsQ K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 304.0
TLS3_k127_1984951_17 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003059 279.0
TLS3_k127_1984951_18 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002719 253.0
TLS3_k127_1984951_19 PFAM Flagellar assembly protein FliH Type III secretion system HrpE K02411 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004337 248.0
TLS3_k127_1984951_2 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 573.0
TLS3_k127_1984951_20 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.000000000000000000000000000000000000000000000000000000000000009147 224.0
TLS3_k127_1984951_21 PFAM surface presentation of antigens (SPOA) protein K02417,K03225 - - 0.00000000000000000000000000000000000000000000000000000000000004384 217.0
TLS3_k127_1984951_22 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000000000000000000000000004616 212.0
TLS3_k127_1984951_23 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.000000000000000000000000000000000000000000000000000000006667 201.0
TLS3_k127_1984951_24 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000000000000000000000000000000003385 179.0
TLS3_k127_1984951_25 Flagellar FliJ protein K02413 - - 0.00000000000000000000000000000000000000000000001528 175.0
TLS3_k127_1984951_26 Flagellar hook-length control protein FliK K02414 - - 0.00000000000000000000000000000000000000000001257 176.0
TLS3_k127_1984951_27 FlgN protein K02399 - - 0.000000000000000000000000000000000000001284 152.0
TLS3_k127_1984951_28 Bacterial export proteins, family 3 K02420 - - 0.00000000000000000000000000000000000001811 145.0
TLS3_k127_1984951_29 Flagellar biosynthesis protein, FliO K02418 - - 0.000000000000000000000000000000000004141 143.0
TLS3_k127_1984951_3 PFAM flagellar motor switch protein FliM K02416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 564.0
TLS3_k127_1984951_30 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000004459 121.0
TLS3_k127_1984951_31 PFAM Anti-sigma-28 factor FlgM family protein K02398 - - 0.00000000000000006364 84.0
TLS3_k127_1984951_4 TIGRFAM flagellar motor switch protein FliG K02410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007184 549.0
TLS3_k127_1984951_5 PFAM flagellar basal body FlaE domain protein K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006874 524.0
TLS3_k127_1984951_6 Belongs to the flagella basal body rod proteins family K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 456.0
TLS3_k127_1984951_7 Bacterial flagellin N-terminal helical region K02397 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 439.0
TLS3_k127_1984951_8 Belongs to the flagella basal body rod proteins family K02391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 373.0
TLS3_k127_1984951_9 Plays a role in the flagellum-specific transport system K02419 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 376.0
TLS3_k127_199034_0 - - - - 1.097e-244 764.0
TLS3_k127_199034_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 488.0
TLS3_k127_199034_10 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000319 151.0
TLS3_k127_199034_11 - - - - 0.00000000000001597 79.0
TLS3_k127_199034_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000801 427.0
TLS3_k127_199034_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 422.0
TLS3_k127_199034_4 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 389.0
TLS3_k127_199034_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 - 2.1.1.67 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 339.0
TLS3_k127_199034_6 Hemolysin-type calcium-binding region K11005,K11029 GO:0001906,GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005576,GO:0006873,GO:0006874,GO:0006875,GO:0007204,GO:0008150,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0019725,GO:0019835,GO:0030003,GO:0031640,GO:0035821,GO:0042592,GO:0044179,GO:0044364,GO:0044419,GO:0044764,GO:0048878,GO:0050801,GO:0051480,GO:0051704,GO:0051715,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0072503,GO:0072507,GO:0098771 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 327.0
TLS3_k127_199034_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 303.0
TLS3_k127_199034_8 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003939 258.0
TLS3_k127_199034_9 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000000000000001439 231.0
TLS3_k127_1995319_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1444.0
TLS3_k127_1995319_1 histidine kinase HAMP region domain protein - - - 9e-323 1001.0
TLS3_k127_1995319_10 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007655 499.0
TLS3_k127_1995319_11 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 495.0
TLS3_k127_1995319_12 TIGRFAM radical SAM additional 4Fe4S-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 472.0
TLS3_k127_1995319_13 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 472.0
TLS3_k127_1995319_14 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 462.0
TLS3_k127_1995319_15 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 427.0
TLS3_k127_1995319_16 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606 411.0
TLS3_k127_1995319_17 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 396.0
TLS3_k127_1995319_18 NAD dependent epimerase/dehydratase family K19180 - 1.1.1.339 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 351.0
TLS3_k127_1995319_19 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 341.0
TLS3_k127_1995319_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 6.47e-322 996.0
TLS3_k127_1995319_20 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 320.0
TLS3_k127_1995319_21 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000001118 265.0
TLS3_k127_1995319_22 Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.00000000000000000000000000000000000000000000000000000000000000000000000326 251.0
TLS3_k127_1995319_23 Protein of unknown function (DUF494) K03747 - - 0.0000000000000000000000000000000000000000000000000000000000000003215 223.0
TLS3_k127_1995319_24 Domain of unknown function (DUF4390) - - - 0.000000000000000000000000000000000000000000000000007206 187.0
TLS3_k127_1995319_25 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000002542 162.0
TLS3_k127_1995319_26 Methyltransferase FkbM domain - - - 0.000000000000000000000000000009251 132.0
TLS3_k127_1995319_3 C-methyltransferase C-terminal domain - - - 8.471e-222 695.0
TLS3_k127_1995319_4 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 2.822e-220 687.0
TLS3_k127_1995319_5 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 5.936e-203 633.0
TLS3_k127_1995319_6 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 4.213e-195 612.0
TLS3_k127_1995319_7 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 611.0
TLS3_k127_1995319_8 PFAM NAD-dependent epimerase dehydratase K01709 - 4.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008344 582.0
TLS3_k127_1995319_9 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 546.0
TLS3_k127_200598_0 TIGRFAM heavy metal efflux pump, CzcA family K07787 - - 1.458e-203 636.0
TLS3_k127_200598_1 TIGRFAM efflux transporter, RND family, MFP subunit K07798,K15727 - - 2.128e-196 630.0
TLS3_k127_200598_2 PFAM outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 474.0
TLS3_k127_200598_3 Protein of unknown function, DUF - - - 0.000000000000000000000000000000000000000000000000000002878 196.0
TLS3_k127_200598_4 Copper binding periplasmic protein CusF - - - 0.0000000000003448 74.0
TLS3_k127_200598_5 - - - - 0.0003164 47.0
TLS3_k127_200737_0 May be involved in recombinational repair of damaged DNA K03631 - - 1.619e-253 791.0
TLS3_k127_200737_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000001736 183.0
TLS3_k127_208124_0 DHH family K07462 - - 3.293e-266 829.0
TLS3_k127_208124_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 6.879e-252 782.0
TLS3_k127_208124_2 ACT domain K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 3.032e-239 742.0
TLS3_k127_208124_3 membrane - - - 8.836e-211 661.0
TLS3_k127_208124_4 PFAM CoA-binding domain protein K09181 - - 1.379e-205 644.0
TLS3_k127_208124_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 2.322e-194 614.0
TLS3_k127_208124_6 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 597.0
TLS3_k127_208124_7 Ribosomal protein L9, N-terminal domain K02939 - - 0.00000000000000000000000000000000000000000000000000000000000000000006977 233.0
TLS3_k127_208124_8 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000000000000001364 216.0
TLS3_k127_208124_9 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000000000000005047 158.0
TLS3_k127_2103766_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0 1197.0
TLS3_k127_2103766_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 2.663e-228 715.0
TLS3_k127_2103766_2 Pfam Response regulator receiver - - - 0.0000000000000000000000000001628 118.0
TLS3_k127_2149531_0 Metallopeptidase family M24 K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 489.0
TLS3_k127_2149531_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 338.0
TLS3_k127_2149531_2 TIGRFAM addiction module killer protein - - - 0.0000000000000000000000000000000000000000000000000000000002547 203.0
TLS3_k127_2149531_3 TIGRFAM addiction module antidote protein - - - 0.0000000000000000000000000000000000000000000000000005717 188.0
TLS3_k127_2149531_4 - - - - 0.000000000000000000004769 93.0
TLS3_k127_2149531_5 - - - - 0.000000000000000004907 84.0
TLS3_k127_2150621_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 0.0 1204.0
TLS3_k127_2150621_1 PFAM type II and III secretion system protein K02666 - - 1.014e-286 895.0
TLS3_k127_2150621_2 TIGRFAM type IV pilus assembly protein PilM K02662 - - 2.383e-196 616.0
TLS3_k127_2150621_3 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 501.0
TLS3_k127_2150621_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 321.0
TLS3_k127_2150621_5 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 310.0
TLS3_k127_2150621_6 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001236 267.0
TLS3_k127_2150621_7 Pilus assembly protein, PilP K02665 - - 0.0000000000000000000000000000000000000000000000000000000000000000001394 239.0
TLS3_k127_2163097_0 PFAM polysaccharide biosynthesis protein CapD - - - 4.552e-311 961.0
TLS3_k127_2163097_1 Mur ligase family, catalytic domain K01924 - 6.3.2.8 2.06e-243 759.0
TLS3_k127_2163097_10 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005986 535.0
TLS3_k127_2163097_11 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 491.0
TLS3_k127_2163097_12 Glycosyltransferase Family 4 K02844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000959 490.0
TLS3_k127_2163097_13 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 469.0
TLS3_k127_2163097_14 PFAM Glycosyl transferase, family 4, conserved region K13007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 429.0
TLS3_k127_2163097_15 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 430.0
TLS3_k127_2163097_16 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 417.0
TLS3_k127_2163097_17 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 373.0
TLS3_k127_2163097_18 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 342.0
TLS3_k127_2163097_19 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 313.0
TLS3_k127_2163097_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.979e-231 719.0
TLS3_k127_2163097_20 O-antigen ligase like membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001201 252.0
TLS3_k127_2163097_21 POTRA domain, FtsQ-type - - - 0.0000000000000000000000000000000000000000000002037 177.0
TLS3_k127_2163097_22 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000002196 123.0
TLS3_k127_2163097_23 Methionine biosynthesis protein MetW - - - 0.000000000000000000000002313 113.0
TLS3_k127_2163097_24 Belongs to the N-Me-Phe pilin family K02650 - - 0.000000000000000000000005015 107.0
TLS3_k127_2163097_25 Flagellar assembly protein T, middle domain - - - 0.0000000000000000000001596 112.0
TLS3_k127_2163097_26 - - - - 0.000000000000000000002311 94.0
TLS3_k127_2163097_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 4.222e-202 638.0
TLS3_k127_2163097_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 1.544e-194 614.0
TLS3_k127_2163097_5 Domain of unknown function (DUF3391) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 593.0
TLS3_k127_2163097_6 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 586.0
TLS3_k127_2163097_7 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 540.0
TLS3_k127_2163097_8 Domain of unknown function (DUF3391) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006167 545.0
TLS3_k127_2163097_9 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 536.0
TLS3_k127_2188105_0 Helicase - - - 0.0 1667.0
TLS3_k127_2188105_1 Belongs to the ClpA ClpB family K03694 - - 0.0 1204.0
TLS3_k127_2188105_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 1.61e-231 722.0
TLS3_k127_2188105_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 566.0
TLS3_k127_2188105_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 419.0
TLS3_k127_2188105_5 interspecies interaction between organisms - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 420.0
TLS3_k127_2188105_6 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000007412 238.0
TLS3_k127_2188105_7 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000004744 153.0
TLS3_k127_2188105_8 SMART Cold shock protein K03704 - - 0.00000000000000000000000000000000001318 135.0
TLS3_k127_2277166_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.273e-305 942.0
TLS3_k127_2277166_1 PFAM major facilitator superfamily MFS_1 K08218 - - 1.862e-233 726.0
TLS3_k127_2277166_2 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 477.0
TLS3_k127_2277166_3 TIGRFAM ornithine aminotransferase K00819 - 2.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000006983 254.0
TLS3_k127_2277166_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000005726 162.0
TLS3_k127_2277166_5 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000001242 173.0
TLS3_k127_2277166_6 Resolvase - - - 0.0000002514 55.0
TLS3_k127_235925_0 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 417.0
TLS3_k127_235925_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 384.0
TLS3_k127_235925_10 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000002306 151.0
TLS3_k127_235925_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000001797 153.0
TLS3_k127_235925_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 377.0
TLS3_k127_235925_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 357.0
TLS3_k127_235925_4 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 351.0
TLS3_k127_235925_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006836 265.0
TLS3_k127_235925_6 response regulator K02485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004512 240.0
TLS3_k127_235925_7 response regulator K02485 - - 0.0000000000000000000000000000000000000000000000000000000000000000002805 234.0
TLS3_k127_235925_8 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000003114 212.0
TLS3_k127_235925_9 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000006838 173.0
TLS3_k127_2382200_0 Major Facilitator Superfamily - - - 7.301e-205 642.0
TLS3_k127_2382200_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000884 527.0
TLS3_k127_2382200_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772,K03815 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 482.0
TLS3_k127_2382200_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003999,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0012505,GO:0016192,GO:0016208,GO:0016740,GO:0016757,GO:0016763,GO:0017076,GO:0018130,GO:0019438,GO:0030141,GO:0030554,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0043094,GO:0043101,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 315.0
TLS3_k127_2382200_4 cytochrome d1, heme region K19345 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002404 246.0
TLS3_k127_2382200_5 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.000000000000000000000000000000000005314 139.0
TLS3_k127_2391105_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 9.06e-257 797.0
TLS3_k127_2391105_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 1.936e-198 628.0
TLS3_k127_2391105_2 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 588.0
TLS3_k127_2391105_3 PFAM sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 408.0
TLS3_k127_2391105_4 Dihydrodipicolinate reductase, C-terminus K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 387.0
TLS3_k127_2391105_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 359.0
TLS3_k127_2391105_6 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000000000000000000003104 230.0
TLS3_k127_2391105_7 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000001102 231.0
TLS3_k127_2391105_8 17 kDa surface antigen K06077 - - 0.0000000000000000000000000000000000000000000000007383 179.0
TLS3_k127_2400143_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 4.932e-202 641.0
TLS3_k127_2400143_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 415.0
TLS3_k127_2400143_2 MscS Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 377.0
TLS3_k127_2466016_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 523.0
TLS3_k127_2466016_1 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 432.0
TLS3_k127_2466016_2 Sigma factor PP2C-like phosphatases K20977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 333.0
TLS3_k127_2466016_3 CheD chemotactic sensory transduction K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 300.0
TLS3_k127_2466016_4 COG2202 FOG PAS PAC domain K03776 - - 0.0000000000000000000000000000000000000000000172 186.0
TLS3_k127_2466016_5 STAS domain K20978 - - 0.0000000000000000000000143 104.0
TLS3_k127_2466016_6 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000002005 91.0
TLS3_k127_2484464_0 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031,K02032 - - 6.03e-310 971.0
TLS3_k127_2484464_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.382e-296 911.0
TLS3_k127_2484464_2 LysM domain K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 582.0
TLS3_k127_2484464_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 460.0
TLS3_k127_2484464_4 Bacterial protein of unknown function (DUF883) - - - 0.00000000000000000000000000000000000000003382 154.0
TLS3_k127_2484464_5 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000000000000000000000000000000002957 141.0
TLS3_k127_2513150_0 PFAM ATP-binding region ATPase domain protein K11527 - 2.7.13.3 4.782e-226 732.0
TLS3_k127_2542615_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 524.0
TLS3_k127_2542615_1 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 418.0
TLS3_k127_2542615_2 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 293.0
TLS3_k127_2542615_3 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 292.0
TLS3_k127_2542615_4 PFAM 17 kDa surface antigen - - - 0.0000000000000000000000000000000000000000000000000001082 190.0
TLS3_k127_2542615_5 Glyoxalase-like domain K06996 - - 0.00000000000000000000000000000000000000000000003612 172.0
TLS3_k127_2614343_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1118.0
TLS3_k127_2614343_1 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008979 420.0
TLS3_k127_2614343_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 395.0
TLS3_k127_2614343_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 344.0
TLS3_k127_2614343_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 319.0
TLS3_k127_2614343_5 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 310.0
TLS3_k127_2614343_6 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000005994 163.0
TLS3_k127_2614343_7 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000001352 118.0
TLS3_k127_2662476_0 Protein of unknown function (DUF1015) - - - 4.884e-226 704.0
TLS3_k127_2662476_1 Diguanylate cyclase K13069 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009702 597.0
TLS3_k127_2662476_10 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000003427 140.0
TLS3_k127_2662476_11 Pentapeptide repeats (9 copies) - - - 0.000000000000000000000000001026 120.0
TLS3_k127_2662476_2 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 550.0
TLS3_k127_2662476_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008342 536.0
TLS3_k127_2662476_4 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 439.0
TLS3_k127_2662476_5 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 431.0
TLS3_k127_2662476_6 Four helix bundle sensory module for signal transduction K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 391.0
TLS3_k127_2662476_7 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 313.0
TLS3_k127_2662476_8 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000001073 240.0
TLS3_k127_2662476_9 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000000000000000000008403 209.0
TLS3_k127_2669643_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.36e-287 886.0
TLS3_k127_2669643_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.069e-252 782.0
TLS3_k127_2669643_10 PFAM Class I peptide chain release factor K15034 - - 0.000000000000000000000000000000000000000000000000000001252 196.0
TLS3_k127_2669643_11 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000000008453 148.0
TLS3_k127_2669643_12 Ribosomal protein L30p/L7e K02907 - - 0.0000000000000000000000009205 108.0
TLS3_k127_2669643_13 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000001481 74.0
TLS3_k127_2669643_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 576.0
TLS3_k127_2669643_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008839 560.0
TLS3_k127_2669643_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 389.0
TLS3_k127_2669643_5 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 303.0
TLS3_k127_2669643_6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003113 256.0
TLS3_k127_2669643_7 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001247 246.0
TLS3_k127_2669643_8 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000000000000000006377 235.0
TLS3_k127_2669643_9 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000000000005178 220.0
TLS3_k127_2670774_0 Flagellar hook-associated protein 2 N-terminus K02407 - - 1.632e-226 721.0
TLS3_k127_2670774_1 Glycosyl transferase family 41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007621 619.0
TLS3_k127_2670774_10 Gram-negative-bacterium-type cell outer membrane assembly K01136,K07287 - 3.1.6.13 0.00000000000000000000000000000000000000000000000000000000009642 228.0
TLS3_k127_2670774_11 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.000000000000000000000000000000000000000000000000000000002038 208.0
TLS3_k127_2670774_12 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.00000000000000000000000000000000000000000000000000000118 198.0
TLS3_k127_2670774_13 Flagellar hook-length control protein FliK - - - 0.000000000000000000000000000000000000000000000000000001921 198.0
TLS3_k127_2670774_14 Flagellar protein FliS K02422 - - 0.000000000000000000000000000000000000000000000000000009534 193.0
TLS3_k127_2670774_15 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000001128 198.0
TLS3_k127_2670774_16 FlhB HrpN YscU SpaS Family K04061 - - 0.000000000000000000000000000000000001098 141.0
TLS3_k127_2670774_17 Flagellar hook-length control protein FliK - - - 0.000000000000000000000000000002609 124.0
TLS3_k127_2670774_18 FlaG protein K06603 - - 0.00000000000000000000000000001285 122.0
TLS3_k127_2670774_19 Flagellar protein FliT K02423 - - 0.00000000000000000000000000115 117.0
TLS3_k127_2670774_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 511.0
TLS3_k127_2670774_20 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000001261 104.0
TLS3_k127_2670774_21 COGs COG0790 FOG TPR repeat SEL1 subfamily - - - 0.00000000000000000008156 98.0
TLS3_k127_2670774_22 glycosyl transferase family - - - 0.0000000000000000001883 104.0
TLS3_k127_2670774_3 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 479.0
TLS3_k127_2670774_4 Cephalosporin hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 398.0
TLS3_k127_2670774_5 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 292.0
TLS3_k127_2670774_6 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000003945 235.0
TLS3_k127_2670774_7 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.000000000000000000000000000000000000000000000000000000000000000001559 232.0
TLS3_k127_2670774_8 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.000000000000000000000000000000000000000000000000000000000000005313 225.0
TLS3_k127_2670774_9 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.00000000000000000000000000000000000000000000000000000000000001252 224.0
TLS3_k127_2697323_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 365.0
TLS3_k127_2697323_1 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 340.0
TLS3_k127_2697323_2 PFAM ABC transporter related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004134 268.0
TLS3_k127_2697323_3 Protein of unknown function (DUF3301) - - - 0.0000000000000000000000000000000001722 135.0
TLS3_k127_2697323_4 Hemerythrin-like metal-binding protein - - - 0.000000000000000001485 91.0
TLS3_k127_272744_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 3.679e-234 726.0
TLS3_k127_272744_1 Starch synthase catalytic domain K00703 - 2.4.1.21 3.809e-197 623.0
TLS3_k127_272744_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009976 406.0
TLS3_k127_272744_3 SpoU rRNA Methylase family K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 364.0
TLS3_k127_272744_4 Segregation and condensation complex subunit ScpB K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 292.0
TLS3_k127_272744_5 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000000000000000000003064 233.0
TLS3_k127_2803431_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 5.927e-279 866.0
TLS3_k127_2803431_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 6.966e-208 649.0
TLS3_k127_2803431_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000004862 202.0
TLS3_k127_2803431_11 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 K22132 - - 0.0000000000000000000000000000000000000000000000000000008031 202.0
TLS3_k127_2803431_12 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000000000000004763 146.0
TLS3_k127_2803431_13 DsrC like protein K11179 - - 0.000000000000000000000000000004574 123.0
TLS3_k127_2803431_15 Glucose inhibited division protein A K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000001266 98.0
TLS3_k127_2803431_17 - - - - 0.000000000000003558 78.0
TLS3_k127_2803431_2 Sulphur transport K07112 - - 2.93e-201 637.0
TLS3_k127_2803431_3 Histidine kinase K07673 - 2.7.13.3 3.104e-200 630.0
TLS3_k127_2803431_4 Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 498.0
TLS3_k127_2803431_5 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007787 380.0
TLS3_k127_2803431_6 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 312.0
TLS3_k127_2803431_7 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 306.0
TLS3_k127_2803431_8 rhodanese-related sulfurtransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001525 246.0
TLS3_k127_2803431_9 Bacterial regulatory proteins, luxR family K07684 - - 0.0000000000000000000000000000000000000000000000000000000000001045 221.0
TLS3_k127_2804751_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1350.0
TLS3_k127_2804751_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0 1295.0
TLS3_k127_2804751_10 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 365.0
TLS3_k127_2804751_11 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 336.0
TLS3_k127_2804751_12 Pfam Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 317.0
TLS3_k127_2804751_13 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000000618 213.0
TLS3_k127_2804751_14 - - - - 0.00000000000000000000000000000000000000005007 170.0
TLS3_k127_2804751_15 metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000001591 128.0
TLS3_k127_2804751_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0 1030.0
TLS3_k127_2804751_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 7.623e-239 743.0
TLS3_k127_2804751_4 PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 3.474e-210 662.0
TLS3_k127_2804751_5 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 512.0
TLS3_k127_2804751_6 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 412.0
TLS3_k127_2804751_7 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 391.0
TLS3_k127_2804751_8 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 371.0
TLS3_k127_2804751_9 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 378.0
TLS3_k127_2870674_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.034e-316 979.0
TLS3_k127_2870674_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 1.045e-270 871.0
TLS3_k127_2870674_10 Diguanylate cyclase K21021 - 2.7.7.65 0.0000000000000000000000000000000000000000000000001821 203.0
TLS3_k127_2870674_11 Preprotein translocase subunit K03210 - - 0.0000000000000000000000000000000000000000006535 158.0
TLS3_k127_2870674_12 Response regulator receiver domain K03413 - - 0.000000000000000000000000000000000000000003576 158.0
TLS3_k127_2870674_13 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000181 135.0
TLS3_k127_2870674_14 response regulator K03413,K07688 - - 0.000000000000000000000003485 106.0
TLS3_k127_2870674_15 histidine kinase HAMP region domain protein K03406 - - 0.0000000006675 66.0
TLS3_k127_2870674_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 9.922e-215 670.0
TLS3_k127_2870674_3 response regulator - - - 1.855e-198 634.0
TLS3_k127_2870674_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 524.0
TLS3_k127_2870674_5 type II secretion system protein E K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 488.0
TLS3_k127_2870674_6 TRAP transporter solute receptor TAXI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 435.0
TLS3_k127_2870674_7 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 306.0
TLS3_k127_2870674_8 Glycine zipper 2TM domain - - - 0.0000000000000000000000000000000000000000000000000000000000273 214.0
TLS3_k127_2870674_9 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000001659 201.0
TLS3_k127_296937_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1101.0
TLS3_k127_296937_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 6.563e-293 906.0
TLS3_k127_296937_10 PFAM Peptidase S24 S26A S26B, conserved region K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000007037 232.0
TLS3_k127_296937_11 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.0000000000000000000000000000000000000000000000000000000000000000002177 232.0
TLS3_k127_296937_12 Lipid A 3-O-deacylase (PagL) - - - 0.000000000000000000000000000000000000000000000000000002395 198.0
TLS3_k127_296937_13 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000001149 167.0
TLS3_k127_296937_14 - K19168 - - 0.0000001146 59.0
TLS3_k127_296937_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 1.206e-236 744.0
TLS3_k127_296937_3 PFAM peptidase S1 and S6 chymotrypsin Hap K04771 - 3.4.21.107 3.842e-206 649.0
TLS3_k127_296937_4 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 531.0
TLS3_k127_296937_5 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 449.0
TLS3_k127_296937_6 MucB/RseB C-terminal domain K03598 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 436.0
TLS3_k127_296937_7 TIGRFAM RNA polymerase sigma factor RpoE K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 366.0
TLS3_k127_296937_8 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 355.0
TLS3_k127_296937_9 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 321.0
TLS3_k127_3071028_0 LapD/MoxY periplasmic domain - - - 4.782e-199 638.0
TLS3_k127_3071028_1 HlyD family secretion protein K12542 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 619.0
TLS3_k127_3071028_10 luxR family - - - 0.000000000000000000000000000000000000000000001451 173.0
TLS3_k127_3071028_11 periplasmic secreted protein - - - 0.00000000000000000000000000000000000000000000277 173.0
TLS3_k127_3071028_12 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.000000000000000000000000000000000000000000007216 164.0
TLS3_k127_3071028_13 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000000000001539 88.0
TLS3_k127_3071028_14 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000001144 81.0
TLS3_k127_3071028_2 AMP-forming long-chain acyl-CoA synthetase K01897 GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009987,GO:0015645,GO:0016020,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0030312,GO:0032787,GO:0042546,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044464,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:1901576 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 584.0
TLS3_k127_3071028_3 COG1538 Outer membrane protein K12543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 408.0
TLS3_k127_3071028_4 PFAM Spermine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 343.0
TLS3_k127_3071028_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 336.0
TLS3_k127_3071028_6 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 294.0
TLS3_k127_3071028_7 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.00000000000000000000000000000000000000000000000000000000000002441 223.0
TLS3_k127_3071028_8 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000004509 207.0
TLS3_k127_3071028_9 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000003975 204.0
TLS3_k127_3107735_0 Parallel beta-helix repeats - - - 0.0 1370.0
TLS3_k127_3107735_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 1.916e-265 842.0
TLS3_k127_3107735_10 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 416.0
TLS3_k127_3107735_11 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 385.0
TLS3_k127_3107735_12 PAC sensor-containing diguanylate cyclase phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007908 354.0
TLS3_k127_3107735_13 response regulator K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 322.0
TLS3_k127_3107735_14 response regulator K14979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 300.0
TLS3_k127_3107735_15 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001279 289.0
TLS3_k127_3107735_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003444 265.0
TLS3_k127_3107735_17 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005418 247.0
TLS3_k127_3107735_18 Type II secretion system (T2SS), protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000000000001563 226.0
TLS3_k127_3107735_19 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000000000000000006802 218.0
TLS3_k127_3107735_2 glucan 1,4-alpha-glucosidase activity - - - 5.052e-243 758.0
TLS3_k127_3107735_20 Domain of unknown function (DUF4124) K08309 - - 0.000000000000000000000000000000000000000000000000000000008708 204.0
TLS3_k127_3107735_21 RESPONSE REGULATOR receiver - - - 0.000000000000000000000000000000000000000000000000000001926 196.0
TLS3_k127_3107735_22 prepilin-type N-terminal cleavage methylation K02456 - - 0.0000000000000000000000000000000000000000000000000003061 187.0
TLS3_k127_3107735_23 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000004757 179.0
TLS3_k127_3107735_24 cheY-homologous receiver domain K11443 - - 0.00000000000000000000000000000000000000000000002515 174.0
TLS3_k127_3107735_25 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000000000000000000002775 176.0
TLS3_k127_3107735_26 Type II secretory pathway, pseudopilin - - - 0.00000000000000000000000000000000000000000000007997 173.0
TLS3_k127_3107735_27 Pilus assembly protein, PilO - - - 0.00000000000000000000000000000000006799 146.0
TLS3_k127_3107735_28 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000000000002856 127.0
TLS3_k127_3107735_29 - - - - 0.00000000000000000000000000000006297 139.0
TLS3_k127_3107735_3 Cohesin domain K02453 - - 3.794e-226 725.0
TLS3_k127_3107735_30 - - - - 0.000000000000000000000002991 109.0
TLS3_k127_3107735_31 - - - - 0.0000000000000000001869 96.0
TLS3_k127_3107735_4 His Kinase A (phosphoacceptor) domain - - - 2.167e-205 645.0
TLS3_k127_3107735_5 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 602.0
TLS3_k127_3107735_6 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 500.0
TLS3_k127_3107735_7 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 458.0
TLS3_k127_3107735_8 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 449.0
TLS3_k127_3107735_9 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 437.0
TLS3_k127_3121581_0 CoA binding domain K09181 - - 1.494e-298 922.0
TLS3_k127_3121581_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 610.0
TLS3_k127_3121581_2 AcrB/AcrD/AcrF family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 583.0
TLS3_k127_3121581_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 487.0
TLS3_k127_3121581_4 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 476.0
TLS3_k127_3121581_5 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 455.0
TLS3_k127_3121581_6 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 360.0
TLS3_k127_3121581_7 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000003624 133.0
TLS3_k127_3121581_8 Helix-turn-helix domain - - - 0.00000000000000000000000000000001432 129.0
TLS3_k127_3123079_0 Sodium:solute symporter family K14393 - - 5e-324 1003.0
TLS3_k127_3123079_1 SMART CBS domain containing protein K07182 - - 9.959e-241 760.0
TLS3_k127_3123079_10 Domain of unknown function (DUF4212) - - - 0.000000000000000000000000000000000001056 140.0
TLS3_k127_3123079_11 - - - - 0.00000000000000000000000000000000001495 138.0
TLS3_k127_3123079_12 Large family of predicted nucleotide-binding domains K07175 - - 0.00002074 47.0
TLS3_k127_3123079_2 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 608.0
TLS3_k127_3123079_3 SMART GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 381.0
TLS3_k127_3123079_4 Two component transcriptional regulator, winged helix family K02483,K07666,K07774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 361.0
TLS3_k127_3123079_5 chemotaxis protein K03410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005936 262.0
TLS3_k127_3123079_6 PFAM Exonuclease RNase T and DNA polymerase III K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000002063 226.0
TLS3_k127_3123079_7 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000001987 212.0
TLS3_k127_3123079_8 Thioesterase K18700 - 3.1.2.29 0.0000000000000000000000000000000000000000000000000000000005434 207.0
TLS3_k127_3123079_9 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000004543 175.0
TLS3_k127_3127877_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.384e-260 805.0
TLS3_k127_3127877_1 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009008 532.0
TLS3_k127_3127877_2 ATPase involved in DNA repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 445.0
TLS3_k127_3127877_3 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008397 392.0
TLS3_k127_3127877_4 Pentapeptide repeats (9 copies) - - - 0.000000000000000000000000000000000001314 144.0
TLS3_k127_3148933_0 Amidohydrolase family K01465 - 3.5.2.3 2.149e-243 759.0
TLS3_k127_3148933_1 Glutamate-cysteine ligase K01919 - 6.3.2.2 6.258e-242 752.0
TLS3_k127_3148933_2 PFAM aspartate ornithine carbamoyltransferase Asp Orn-binding region K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 572.0
TLS3_k127_3148933_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 477.0
TLS3_k127_3148933_4 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009131 319.0
TLS3_k127_3148933_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000000000000000000000000005789 228.0
TLS3_k127_3148933_6 PFAM PTS system fructose subfamily IIA component K02821 - 2.7.1.194 0.0000000000000002626 79.0
TLS3_k127_3164446_0 PFAM Type II secretion system protein E K02454 - - 3.247e-224 707.0
TLS3_k127_3164446_1 General secretion pathway protein D K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 520.0
TLS3_k127_3164446_10 PFAM General secretion pathway protein K K02460 - - 0.000000000000000000000000000000000000000000000000000000000009774 219.0
TLS3_k127_3164446_11 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000000000000000000000000000000000005839 204.0
TLS3_k127_3164446_12 fimbrial assembly K02461 - - 0.000000000000000000000000000000000000000000000139 187.0
TLS3_k127_3164446_13 - - - - 0.0000000000000000000000000000000000000000003106 173.0
TLS3_k127_3164446_14 Glycosyltransferase like family - - - 0.00000000000000000000000000000000000000002649 166.0
TLS3_k127_3164446_15 General secretion pathway protein H K02457 - - 0.000000000000000000000000000000000000006482 150.0
TLS3_k127_3164446_16 - - - - 0.00000000000000000000000000000000000009771 162.0
TLS3_k127_3164446_17 - - - - 0.000000000000000000000000000000000003018 158.0
TLS3_k127_3164446_18 - - - - 0.0000000000000000000000000000000002119 148.0
TLS3_k127_3164446_19 Pfam:N_methyl_2 K02459 - - 0.00000000000000000000000000000003007 134.0
TLS3_k127_3164446_2 TIGRFAM Undecaprenyl-phosphate glucose phosphotransferase K03606 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 458.0
TLS3_k127_3164446_20 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000003651 124.0
TLS3_k127_3164446_21 Prokaryotic N-terminal methylation motif K02458 - - 0.000000000000000000000003094 108.0
TLS3_k127_3164446_22 Glycosyl transferase family 2 - - - 0.0000000000000000000008466 104.0
TLS3_k127_3164446_23 Pfam:T4SC K02463 - - 0.00000000000004764 80.0
TLS3_k127_3164446_24 general secretion pathway protein K02462 - - 0.0000000000001885 78.0
TLS3_k127_3164446_25 Glycosyl transferase family 41 - - - 0.00007828 46.0
TLS3_k127_3164446_3 Type II secretion system K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 449.0
TLS3_k127_3164446_4 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 382.0
TLS3_k127_3164446_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 349.0
TLS3_k127_3164446_6 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 310.0
TLS3_k127_3164446_7 Ribosomal protein L11 methyltransferase (PrmA) K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001066 277.0
TLS3_k127_3164446_8 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004012 277.0
TLS3_k127_3164446_9 Type II secretion system (T2SS), protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000004679 210.0
TLS3_k127_3189616_0 Homoserine dehydrogenase K00003 - 1.1.1.3 5.614e-256 792.0
TLS3_k127_3189616_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 5.14e-254 789.0
TLS3_k127_3189616_10 Protein of unknown function (DUF1778) - - - 0.00000000000000000000000000000000323 131.0
TLS3_k127_3189616_11 - - - - 0.000000000000000000000000000002217 128.0
TLS3_k127_3189616_12 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.00000000000000006846 87.0
TLS3_k127_3189616_2 PFAM aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 6.587e-253 781.0
TLS3_k127_3189616_3 Threonine synthase K01733 - 4.2.3.1 4.87e-234 730.0
TLS3_k127_3189616_4 domain, Protein - - - 6.872e-205 672.0
TLS3_k127_3189616_5 ZIP Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 365.0
TLS3_k127_3189616_6 Histidine kinase K07638 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 376.0
TLS3_k127_3189616_7 response regulator K02483,K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 349.0
TLS3_k127_3189616_8 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000003781 209.0
TLS3_k127_3189616_9 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000000000000000852 175.0
TLS3_k127_3212358_0 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 1.286e-221 698.0
TLS3_k127_3212358_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 1.814e-199 623.0
TLS3_k127_3212358_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 581.0
TLS3_k127_3212358_3 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 344.0
TLS3_k127_3212358_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 282.0
TLS3_k127_3212358_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000000000009651 231.0
TLS3_k127_3212358_6 - - - - 0.000000000000000000000000000000000000000000003664 176.0
TLS3_k127_3212358_7 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000000000000532 130.0
TLS3_k127_3212358_8 Putative addiction module component - - - 0.0000000000000000000000004199 105.0
TLS3_k127_3212358_9 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000001457 76.0
TLS3_k127_3221465_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 547.0
TLS3_k127_3221465_1 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 357.0
TLS3_k127_3267926_0 AMP-dependent synthetase - - - 0.0 1435.0
TLS3_k127_3267926_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.775e-311 960.0
TLS3_k127_3267926_10 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 436.0
TLS3_k127_3267926_11 PFAM PEGA domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 416.0
TLS3_k127_3267926_12 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 408.0
TLS3_k127_3267926_13 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 383.0
TLS3_k127_3267926_14 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 366.0
TLS3_k127_3267926_15 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 343.0
TLS3_k127_3267926_16 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 348.0
TLS3_k127_3267926_17 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006728 323.0
TLS3_k127_3267926_18 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 310.0
TLS3_k127_3267926_19 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 297.0
TLS3_k127_3267926_2 Histidine kinase K14978 - - 1.065e-230 737.0
TLS3_k127_3267926_20 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000004417 278.0
TLS3_k127_3267926_21 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006346 261.0
TLS3_k127_3267926_22 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000000000000000000000000000001261 214.0
TLS3_k127_3267926_23 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000004532 211.0
TLS3_k127_3267926_24 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000003595 215.0
TLS3_k127_3267926_25 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000001899 198.0
TLS3_k127_3267926_26 COG2826 Transposase and inactivated derivatives, IS30 family - - - 0.00000000000000000000000000000000000000000002215 170.0
TLS3_k127_3267926_27 PFAM SpoVT AbrB - - - 0.000000000000000000000000000000003984 129.0
TLS3_k127_3267926_28 - - - - 0.0000000000000000000218 96.0
TLS3_k127_3267926_29 Trm112p-like protein K09791 - - 0.00000000000000006889 81.0
TLS3_k127_3267926_3 Major facilitator Superfamily K06902 - - 3.895e-215 674.0
TLS3_k127_3267926_30 - - - - 0.00005706 49.0
TLS3_k127_3267926_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009524 588.0
TLS3_k127_3267926_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 580.0
TLS3_k127_3267926_6 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 481.0
TLS3_k127_3267926_7 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 443.0
TLS3_k127_3267926_8 Integrase, catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 439.0
TLS3_k127_3267926_9 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 422.0
TLS3_k127_327569_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 6.182e-221 691.0
TLS3_k127_327569_1 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 557.0
TLS3_k127_327569_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 336.0
TLS3_k127_327569_3 PFAM Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 304.0
TLS3_k127_327569_4 4Fe-4S dicluster domain K00184 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002519 259.0
TLS3_k127_327569_5 PFAM Cytochrome C - - - 0.000000000000000000000000000005919 134.0
TLS3_k127_327569_6 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000004835 75.0
TLS3_k127_3288375_0 Involved in the TonB-independent uptake of proteins K03641 - - 6.87e-223 696.0
TLS3_k127_3288375_1 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 8.982e-205 645.0
TLS3_k127_3288375_2 Soluble lytic murein transglycosylase L domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 596.0
TLS3_k127_3288375_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 383.0
TLS3_k127_3288375_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 340.0
TLS3_k127_3288375_5 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008879 287.0
TLS3_k127_3288375_6 TolA C-terminal K03646 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003626 251.0
TLS3_k127_3288375_7 OmpA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000627 228.0
TLS3_k127_3288375_8 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000001618 130.0
TLS3_k127_331842_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1112.0
TLS3_k127_331842_1 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 516.0
TLS3_k127_331842_2 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004947 270.0
TLS3_k127_3355580_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 5.297e-200 627.0
TLS3_k127_3355580_1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 497.0
TLS3_k127_3355580_2 Tautomerase enzyme K01821 - 5.3.2.6 0.00000000000000000000000002543 109.0
TLS3_k127_33897_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1219.0
TLS3_k127_33897_1 Participates in both transcription termination and antitermination K02600 - - 2.297e-264 819.0
TLS3_k127_33897_2 Membrane - - - 7.086e-218 710.0
TLS3_k127_33897_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 442.0
TLS3_k127_33897_4 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000000000000000000000000002643 233.0
TLS3_k127_33897_5 ABC transporter transmembrane region K11004 - - 0.00000000000000000000000000000000000000000000000000000000000000002367 232.0
TLS3_k127_33897_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000000000000000001852 196.0
TLS3_k127_33897_7 TIGRFAM type I secretion membrane fusion protein, HlyD K02022,K11003 - - 0.00000001863 59.0
TLS3_k127_33897_8 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000686 44.0
TLS3_k127_3422130_0 B3/4 domain K01890 - 6.1.1.20 0.0 1171.0
TLS3_k127_3422130_1 Threonyl and Alanyl tRNA synthetase second additional domain K01868 - 6.1.1.3 0.0 1155.0
TLS3_k127_3422130_10 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 439.0
TLS3_k127_3422130_11 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 440.0
TLS3_k127_3422130_12 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 422.0
TLS3_k127_3422130_13 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 354.0
TLS3_k127_3422130_14 PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 361.0
TLS3_k127_3422130_15 Lysin motif K06194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 351.0
TLS3_k127_3422130_16 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 309.0
TLS3_k127_3422130_17 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 297.0
TLS3_k127_3422130_18 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 287.0
TLS3_k127_3422130_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002736 280.0
TLS3_k127_3422130_2 Histidine kinase - - - 2.593e-309 976.0
TLS3_k127_3422130_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000192 275.0
TLS3_k127_3422130_21 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000932 261.0
TLS3_k127_3422130_22 Histidine kinase K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000009216 267.0
TLS3_k127_3422130_23 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008506 248.0
TLS3_k127_3422130_24 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000004278 250.0
TLS3_k127_3422130_25 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000000000000008392 211.0
TLS3_k127_3422130_26 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000001215 204.0
TLS3_k127_3422130_27 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000000000000005863 190.0
TLS3_k127_3422130_28 PFAM regulatory protein, MerR - - - 0.00000000000000000000000000000000000000000000009261 171.0
TLS3_k127_3422130_29 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000000000000000000000000000003361 168.0
TLS3_k127_3422130_3 ABC transporter transmembrane region K06147 - - 5.856e-305 944.0
TLS3_k127_3422130_30 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000885 175.0
TLS3_k127_3422130_31 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000000000007199 129.0
TLS3_k127_3422130_32 - - - - 0.00000000000000000000000000003208 137.0
TLS3_k127_3422130_33 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000000000000577 113.0
TLS3_k127_3422130_34 - - - - 0.00000000000000004717 89.0
TLS3_k127_3422130_36 histidine kinase HAMP region domain protein K03406 - - 0.000000000001874 74.0
TLS3_k127_3422130_38 Belongs to the 'phage' integrase family - - - 0.000003899 48.0
TLS3_k127_3422130_39 COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain K04771 - 3.4.21.107 0.00009076 56.0
TLS3_k127_3422130_4 PFAM ABC-1 domain protein K03688 - - 4.024e-298 926.0
TLS3_k127_3422130_5 Pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 4.33e-241 750.0
TLS3_k127_3422130_6 DinB superfamily - - - 4.575e-237 738.0
TLS3_k127_3422130_7 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 1.188e-213 668.0
TLS3_k127_3422130_8 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 591.0
TLS3_k127_3422130_9 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 439.0
TLS3_k127_343291_0 Enoyl-CoA hydratase/isomerase K07516 - 1.1.1.35 0.0 1364.0
TLS3_k127_343291_1 AMP-binding enzyme K01897 - 6.2.1.3 8.928e-289 896.0
TLS3_k127_343291_10 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000001075 214.0
TLS3_k127_343291_11 PFAM thioesterase superfamily protein K10806 - - 0.000000000000000000000000000000000000000000000000000000009071 214.0
TLS3_k127_343291_12 - - - - 0.000000000000000000000000000000000000000000000000005995 188.0
TLS3_k127_343291_13 Domain of Unknown Function (DUF1540) - - - 0.0000000000000000000000000000000004049 134.0
TLS3_k127_343291_14 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000000000000000000002714 134.0
TLS3_k127_343291_15 nucleic acid-binding protein contains PIN domain - - - 0.0008791 47.0
TLS3_k127_343291_2 AcyL-CoA dehydrogenase K06445 - - 9.854e-288 906.0
TLS3_k127_343291_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.68e-226 708.0
TLS3_k127_343291_4 PFAM alanine dehydrogenase PNT domain protein K00259 - 1.4.1.1 3.692e-206 644.0
TLS3_k127_343291_5 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 394.0
TLS3_k127_343291_6 BRO family, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 320.0
TLS3_k127_343291_7 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 314.0
TLS3_k127_343291_8 SMART GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 298.0
TLS3_k127_343291_9 Belongs to the UPF0178 family K09768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004769 269.0
TLS3_k127_348042_0 chemotaxis protein K03407 - 2.7.13.3 2.634e-278 873.0
TLS3_k127_348042_1 chemotaxis K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001237 268.0
TLS3_k127_348042_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004319 264.0
TLS3_k127_348042_3 Response regulator receiver K03413 - - 0.000000000000000000000000000000000000000000000000000000000000003615 218.0
TLS3_k127_348042_4 STAS domain - - - 0.000000000000000000000000000003241 123.0
TLS3_k127_3484827_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1244.0
TLS3_k127_3484827_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 4.02e-243 759.0
TLS3_k127_3484827_2 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 531.0
TLS3_k127_3533667_0 Hsp90 protein K04079 - - 0.0 1075.0
TLS3_k127_3533667_1 PFAM DEAD DEAH box helicase domain protein - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 - 1.397e-268 833.0
TLS3_k127_3533667_10 Nucleotidyltransferase domain K07075 - - 0.000000000000000000000000000000000000000000000582 167.0
TLS3_k127_3533667_11 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000009735 184.0
TLS3_k127_3533667_12 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000000006924 148.0
TLS3_k127_3533667_13 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000000000006562 134.0
TLS3_k127_3533667_14 plasmid stabilization protein K21495 - - 0.000000000000000009116 85.0
TLS3_k127_3533667_15 restriction modification system DNA specificity K01154 - 3.1.21.3 0.000000001938 59.0
TLS3_k127_3533667_16 Elongation factor Tu domain 2 K06207 - - 0.000000232 53.0
TLS3_k127_3533667_2 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 559.0
TLS3_k127_3533667_3 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 522.0
TLS3_k127_3533667_4 PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008902 417.0
TLS3_k127_3533667_5 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004044 280.0
TLS3_k127_3533667_6 - - - - 0.000000000000000000000000000000000000000000000000000000006499 205.0
TLS3_k127_3533667_7 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000000000000000000000000004499 194.0
TLS3_k127_3533667_8 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000001677 176.0
TLS3_k127_3533667_9 nuclease activity K07062 - - 0.0000000000000000000000000000000000000000000002173 171.0
TLS3_k127_357140_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0 2089.0
TLS3_k127_357140_1 PFAM sodium calcium exchanger membrane region K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 587.0
TLS3_k127_357140_10 Protein of unknown function (DUF2934) - - - 0.0000000000000000000006816 100.0
TLS3_k127_357140_2 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 509.0
TLS3_k127_357140_3 Domain of unknown function DUF21 K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 480.0
TLS3_k127_357140_4 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006477 393.0
TLS3_k127_357140_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 351.0
TLS3_k127_357140_6 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000007872 247.0
TLS3_k127_357140_7 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000000000000000000000000000001478 229.0
TLS3_k127_357140_8 PFAM Sporulation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000002605 213.0
TLS3_k127_357140_9 - - - - 0.0000000000000000000000000000000000000000000000000002502 195.0
TLS3_k127_3603765_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.519e-273 843.0
TLS3_k127_3603765_1 HflC and HflK could encode or regulate a protease K04088 - - 7.302e-200 628.0
TLS3_k127_3603765_10 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000115 137.0
TLS3_k127_3603765_11 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.00000000000000000000175 94.0
TLS3_k127_3603765_2 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 580.0
TLS3_k127_3603765_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 559.0
TLS3_k127_3603765_4 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 475.0
TLS3_k127_3603765_5 Respiratory nitrate reductase beta C-terminal K00371 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006111 394.0
TLS3_k127_3603765_6 nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 304.0
TLS3_k127_3603765_7 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 305.0
TLS3_k127_3603765_8 Nitrate reductase delta subunit K00373 - - 0.000000000000000000000000000000000000000000000000000000000000000002604 230.0
TLS3_k127_3603765_9 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000001548 142.0
TLS3_k127_3609761_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 287.0
TLS3_k127_3609761_1 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001942 273.0
TLS3_k127_3609761_2 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007314 256.0
TLS3_k127_3609761_3 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004833 252.0
TLS3_k127_3609761_4 Cytochrome c - - - 0.00000000000000000000000000005202 124.0
TLS3_k127_3609761_5 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.0000000000000000000003664 100.0
TLS3_k127_3617361_0 TonB dependent receptor K02014 - - 9.333e-320 996.0
TLS3_k127_3617361_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 573.0
TLS3_k127_3617361_2 Uncharacterized conserved protein (DUF2075) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 501.0
TLS3_k127_3617361_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 469.0
TLS3_k127_3617361_4 Uncharacterized conserved protein (DUF2075) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 392.0
TLS3_k127_3617361_5 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000006056 187.0
TLS3_k127_3617361_6 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000000000000000000004899 176.0
TLS3_k127_3617361_7 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000000000001257 169.0
TLS3_k127_3617361_8 PFAM Phage derived protein Gp49-like (DUF891) - - - 0.000000000000000000004166 98.0
TLS3_k127_3617361_9 SpoVT / AbrB like domain K07172 - - 0.00000003584 60.0
TLS3_k127_363149_0 Nucleoside H+ symporter K05820 - - 2.116e-208 652.0
TLS3_k127_363149_1 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 572.0
TLS3_k127_363149_2 regulator K18831 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 540.0
TLS3_k127_363149_3 protein conserved in bacteria K19166 - - 0.0000000000000000000000000000000000000001297 151.0
TLS3_k127_363149_4 - - - - 0.000000000000000000000000985 104.0
TLS3_k127_363149_5 Protein of unknown function DUF45 K07043 - - 0.0000000000000000006516 93.0
TLS3_k127_363149_6 Protein of unknown function (DUF2799) - - - 0.000000004304 62.0
TLS3_k127_363149_7 Nacht domain - - - 0.000001295 60.0
TLS3_k127_3650753_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 402.0
TLS3_k127_3650753_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 345.0
TLS3_k127_3650753_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 306.0
TLS3_k127_3650753_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005231 271.0
TLS3_k127_3671053_0 HELICc2 K03722 - 3.6.4.12 0.0 1115.0
TLS3_k127_3671053_1 HI0933-like protein K07007 - - 1.554e-208 655.0
TLS3_k127_3671053_2 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 321.0
TLS3_k127_3671053_3 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000159 279.0
TLS3_k127_3671053_4 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002925 244.0
TLS3_k127_3671053_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000000000000004023 192.0
TLS3_k127_3671053_6 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000005035 108.0
TLS3_k127_3671053_7 positive regulation of growth - - - 0.000000000000000000000027 101.0
TLS3_k127_369239_0 Glutamine synthetase, catalytic domain K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 1.605e-302 929.0
TLS3_k127_369239_1 Mannose-6-phosphate isomerase K16011 - 2.7.7.13,5.3.1.8 2.285e-249 776.0
TLS3_k127_369239_10 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 364.0
TLS3_k127_369239_11 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002028 256.0
TLS3_k127_369239_12 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001265 244.0
TLS3_k127_369239_13 Winged helix-turn-helix DNA-binding - - - 0.000000000000000000000000000000000000000000000000002247 183.0
TLS3_k127_369239_14 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000000000000000000004775 157.0
TLS3_k127_369239_15 Protein of unknown function (DUF4238) - - - 0.0000000000000000000000000000000000001097 153.0
TLS3_k127_369239_16 Domain of unknown function (DUF4124) - - - 0.0000000000000000000000000000000003493 138.0
TLS3_k127_369239_17 Glycosyl transferases group 1 - - - 0.00000000000000000000000001573 113.0
TLS3_k127_369239_18 Protein of unknown function (DUF4238) - - - 0.00000000000000005506 85.0
TLS3_k127_369239_2 Nitrogen metabolism transcriptional regulator, NtrC, Fis Family K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 1.064e-235 736.0
TLS3_k127_369239_3 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 2.199e-221 688.0
TLS3_k127_369239_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 511.0
TLS3_k127_369239_5 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 506.0
TLS3_k127_369239_6 SMART ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 498.0
TLS3_k127_369239_7 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 468.0
TLS3_k127_369239_8 polysaccharide biosynthetic process K03328 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 439.0
TLS3_k127_369239_9 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008675 396.0
TLS3_k127_3703750_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.839e-197 620.0
TLS3_k127_3703750_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 520.0
TLS3_k127_3703750_2 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 333.0
TLS3_k127_3703750_3 Helix-turn-helix domain K15539 - - 0.00000000000000000000000000000000000007595 154.0
TLS3_k127_3719066_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 1.995e-309 955.0
TLS3_k127_3719066_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 2.424e-238 740.0
TLS3_k127_3719066_10 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000000005502 124.0
TLS3_k127_3719066_11 - - - - 0.000000000000000000000309 100.0
TLS3_k127_3719066_2 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 461.0
TLS3_k127_3719066_3 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 428.0
TLS3_k127_3719066_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 419.0
TLS3_k127_3719066_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 319.0
TLS3_k127_3719066_6 Amino-transferase class IV K02619 - 4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 310.0
TLS3_k127_3719066_7 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 295.0
TLS3_k127_3719066_8 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.000000000000000000000000000000000000000954 149.0
TLS3_k127_3719066_9 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000003652 137.0
TLS3_k127_3727280_0 THUMP K07444 - - 2.517e-219 683.0
TLS3_k127_3727280_1 PFAM type II secretion system protein E K02670 - - 2.18e-207 648.0
TLS3_k127_3727280_2 PFAM ABC transporter related K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 512.0
TLS3_k127_3727280_3 PFAM ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 396.0
TLS3_k127_3727280_4 Uncharacterised protein family (UPF0093) K08973 - - 0.000000000000000000000000000000000000000000000000000000000000000004332 227.0
TLS3_k127_3727280_5 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000004487 224.0
TLS3_k127_3727280_6 PFAM type II secretion system protein E K02669,K12203 - - 0.0000000000000000000000000000000000000000000000000001418 186.0
TLS3_k127_3727280_7 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000002506 129.0
TLS3_k127_3764539_0 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 403.0
TLS3_k127_3764539_1 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000004882 90.0
TLS3_k127_3765319_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 566.0
TLS3_k127_3765319_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 529.0
TLS3_k127_3765319_2 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001767 265.0
TLS3_k127_3765319_3 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000000000000000000000003258 203.0
TLS3_k127_3765319_4 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000000001105 121.0
TLS3_k127_3833667_0 Peptidase family M48 - - - 2.766e-216 681.0
TLS3_k127_3833667_1 serine threonine protein kinase K12132 - 2.7.11.1 1.616e-203 640.0
TLS3_k127_3833667_2 Catalyzes the synthesis of activated sulfate K00860,K00955,K00958 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000701 338.0
TLS3_k127_3833667_3 MoaC family K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009914 269.0
TLS3_k127_3833667_4 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000032 115.0
TLS3_k127_3833667_5 ThiS family K03636 - - 0.00000000002002 70.0
TLS3_k127_3833667_6 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.000000002194 60.0
TLS3_k127_3833667_7 MoaE protein K03635 - 2.8.1.12 0.000408 43.0
TLS3_k127_3836843_0 Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 475.0
TLS3_k127_3836843_1 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 386.0
TLS3_k127_3836843_2 PFAM AMMECR1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001017 268.0
TLS3_k127_3836843_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005739 227.0
TLS3_k127_3836843_4 Protein of unknown function (DUF1778) - - - 0.0000000000000000000000551 102.0
TLS3_k127_3851445_0 PFAM type II secretion system protein E K02669,K12203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 531.0
TLS3_k127_3851445_1 VanZ like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 462.0
TLS3_k127_3851445_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 395.0
TLS3_k127_3851445_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 322.0
TLS3_k127_3851445_4 YGGT family K02221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008912 261.0
TLS3_k127_3851445_5 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000004404 177.0
TLS3_k127_3851445_6 DUF167 K09131 - - 0.00000000000000000000000000000000000000000005252 161.0
TLS3_k127_3851445_7 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000008005 157.0
TLS3_k127_3868424_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0 3647.0
TLS3_k127_3868424_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.355e-307 951.0
TLS3_k127_3868424_2 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 461.0
TLS3_k127_3868424_3 Phosphorylase superfamily K00772,K03815 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 394.0
TLS3_k127_3868424_4 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 291.0
TLS3_k127_3868424_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004544 267.0
TLS3_k127_4028554_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 421.0
TLS3_k127_4028554_1 AcrB/AcrD/AcrF family - - - 0.00000000000000000000000000004632 116.0
TLS3_k127_4028554_2 SpoVT / AbrB like domain K18842 - - 0.00000000000002943 76.0
TLS3_k127_4028554_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000002451 70.0
TLS3_k127_4112835_0 MacB-like periplasmic core domain K02004 - - 7.296e-195 614.0
TLS3_k127_4112835_1 nucleic acid-binding protein contains PIN domain - - - 0.00000000000000000000000000000000000000000000003155 173.0
TLS3_k127_4112835_2 membrane - - - 0.00000000000000000000000000000000003482 136.0
TLS3_k127_4112835_3 Bacterial antitoxin of type II TA system, VapB - - - 0.00000000000000000000001474 100.0
TLS3_k127_4112835_4 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.0000000000000000001326 89.0
TLS3_k127_4112835_5 - - - - 0.000000000000002727 76.0
TLS3_k127_4156333_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1081.0
TLS3_k127_4156333_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 546.0
TLS3_k127_4156333_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 420.0
TLS3_k127_4156333_3 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001288 256.0
TLS3_k127_4156333_4 Protein of unknown function DUF86 - - - 0.00000000000000000000000000000000000000000001457 165.0
TLS3_k127_4156333_5 DNA polymerase beta domain protein region K07075 - - 0.00000000000000000000000000000000000005743 144.0
TLS3_k127_4267900_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 1.91e-207 649.0
TLS3_k127_4267900_1 Chorismate mutase type II K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 532.0
TLS3_k127_4267900_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000004873 146.0
TLS3_k127_4272253_0 SMART heat shock protein DnaJ domain protein K05801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 421.0
TLS3_k127_4272253_1 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 341.0
TLS3_k127_4272253_2 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 306.0
TLS3_k127_4310762_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1517.0
TLS3_k127_4310762_1 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 1.908e-312 958.0
TLS3_k127_4310762_10 PFAM ATP-binding region ATPase domain protein K07645 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 513.0
TLS3_k127_4310762_11 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 501.0
TLS3_k127_4310762_12 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 490.0
TLS3_k127_4310762_13 4fe-4S ferredoxin, iron-sulfur binding domain protein K00384,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 494.0
TLS3_k127_4310762_14 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 477.0
TLS3_k127_4310762_15 Pfam Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 468.0
TLS3_k127_4310762_16 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 456.0
TLS3_k127_4310762_17 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 447.0
TLS3_k127_4310762_18 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 445.0
TLS3_k127_4310762_19 HemY protein N-terminus K02498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 447.0
TLS3_k127_4310762_2 fad dependent oxidoreductase K07137 - - 9.122e-295 910.0
TLS3_k127_4310762_20 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 438.0
TLS3_k127_4310762_21 LytTr DNA-binding domain K08083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 425.0
TLS3_k127_4310762_22 Glycosyltransferase like family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 415.0
TLS3_k127_4310762_23 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 399.0
TLS3_k127_4310762_24 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007853 405.0
TLS3_k127_4310762_25 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 400.0
TLS3_k127_4310762_26 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 395.0
TLS3_k127_4310762_27 Bacterial lipid A biosynthesis acyltransferase K02517,K12974 - 2.3.1.241,2.3.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 397.0
TLS3_k127_4310762_28 PFAM response regulator receiver K02483,K07666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 371.0
TLS3_k127_4310762_29 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 373.0
TLS3_k127_4310762_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.943e-265 824.0
TLS3_k127_4310762_30 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 376.0
TLS3_k127_4310762_31 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 373.0
TLS3_k127_4310762_32 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 361.0
TLS3_k127_4310762_33 Dehydrogenase E1 component K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 299.0
TLS3_k127_4310762_34 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001049 276.0
TLS3_k127_4310762_35 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002804 299.0
TLS3_k127_4310762_36 Nad-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008493 273.0
TLS3_k127_4310762_37 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001288 256.0
TLS3_k127_4310762_38 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002062 251.0
TLS3_k127_4310762_39 ferredoxin-NADP+ reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002588 257.0
TLS3_k127_4310762_4 heat shock protein binding - - - 1.49e-253 795.0
TLS3_k127_4310762_40 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001938 256.0
TLS3_k127_4310762_41 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000001472 241.0
TLS3_k127_4310762_42 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000004091 220.0
TLS3_k127_4310762_43 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000000000003772 209.0
TLS3_k127_4310762_44 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000000000000003339 209.0
TLS3_k127_4310762_45 Dihaem cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000001287 199.0
TLS3_k127_4310762_46 Domain of unknown function (DUF1924) - - - 0.00000000000000000000000000000000000000000000000001592 184.0
TLS3_k127_4310762_47 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000008336 164.0
TLS3_k127_4310762_48 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000000001532 145.0
TLS3_k127_4310762_49 - - - - 0.000000000000000000000000000000000001592 143.0
TLS3_k127_4310762_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 2.18e-250 777.0
TLS3_k127_4310762_50 Oxidoreductase FAD-binding domain protein K00523 - 1.17.1.1 0.000000000000000000000000000000000003309 141.0
TLS3_k127_4310762_51 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000002024 116.0
TLS3_k127_4310762_52 - - - - 0.000000000000000000000000003736 115.0
TLS3_k127_4310762_53 OmpA-like transmembrane domain K03286 - - 0.000000000000000000006871 98.0
TLS3_k127_4310762_55 Membrane - - - 0.00000000000000000004529 102.0
TLS3_k127_4310762_56 ATPases associated with a variety of cellular activities K01990,K09691 - - 0.000000000000007177 83.0
TLS3_k127_4310762_57 - - - - 0.0000000000003855 73.0
TLS3_k127_4310762_58 Glycosyltransferase like family 2 K07011 - - 0.000000000001778 78.0
TLS3_k127_4310762_59 Protein of unknown function (DUF1698) K15257 - - 0.000000002433 68.0
TLS3_k127_4310762_6 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 8.335e-230 715.0
TLS3_k127_4310762_60 Glycosyltransferase like family 2 K07011 - - 0.0000002181 55.0
TLS3_k127_4310762_7 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 2.313e-199 637.0
TLS3_k127_4310762_8 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 548.0
TLS3_k127_4310762_9 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 541.0
TLS3_k127_4333104_0 peptidase, U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 567.0
TLS3_k127_4333104_1 Radical_SAM C-terminal domain K07139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 465.0
TLS3_k127_4333104_2 Peptidase U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 409.0
TLS3_k127_4333104_3 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002858 264.0
TLS3_k127_4333104_4 Transcriptional regulator, Crp Fnr family - - - 0.00000000000000000000000000000000000000000000000000000005688 203.0
TLS3_k127_4333104_5 Sterol-binding domain protein - - - 0.000000000000000000000000000000000000000000000002889 177.0
TLS3_k127_4333104_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000004304 78.0
TLS3_k127_4333104_7 - - - - 0.0000000000000007761 78.0
TLS3_k127_4339213_0 Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 407.0
TLS3_k127_4339213_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 391.0
TLS3_k127_4339213_2 Male sterility protein K00091,K01784 - 1.1.1.219,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 371.0
TLS3_k127_4339213_4 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002683 255.0
TLS3_k127_4341269_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 1.488e-208 654.0
TLS3_k127_4341269_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 470.0
TLS3_k127_4341269_10 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000009335 194.0
TLS3_k127_4341269_11 - - - - 0.000000000000000000000000000000000000000000000002707 175.0
TLS3_k127_4341269_2 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 452.0
TLS3_k127_4341269_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876 449.0
TLS3_k127_4341269_4 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 410.0
TLS3_k127_4341269_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007408 302.0
TLS3_k127_4341269_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 292.0
TLS3_k127_4341269_7 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007037 265.0
TLS3_k127_4341269_8 Bacterial protein of unknown function (DUF899) K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000003457 238.0
TLS3_k127_4341269_9 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000142 223.0
TLS3_k127_434439_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.0 1325.0
TLS3_k127_434439_1 diguanylate cyclase K13590 - 2.7.7.65 1.384e-202 646.0
TLS3_k127_434439_2 histidine kinase dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 408.0
TLS3_k127_434439_3 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 328.0
TLS3_k127_434439_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 309.0
TLS3_k127_434439_5 archaeal or bacterial-type flagellum-dependent cell motility K03414 GO:0001539,GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032991,GO:0036211,GO:0040011,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0097588,GO:0098561,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000339 275.0
TLS3_k127_434439_6 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000000000000000000000000000000000000003049 222.0
TLS3_k127_434439_7 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.00000000000000000000000009037 107.0
TLS3_k127_434439_8 PFAM cytochrome oxidase maturation protein cbb3-type - - - 0.0000000000000000002608 91.0
TLS3_k127_434439_9 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000005289 55.0
TLS3_k127_4352771_0 Type II and III secretion system protein K02453 - - 1.138e-218 694.0
TLS3_k127_4352771_1 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 584.0
TLS3_k127_4352771_2 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000009376 202.0
TLS3_k127_4352771_3 AAA domain - - - 0.0000000000000000006748 93.0
TLS3_k127_4365949_0 PFAM Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase - - - 7.767e-238 748.0
TLS3_k127_4365949_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000004437 164.0
TLS3_k127_4373982_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1043.0
TLS3_k127_4373982_1 PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 4.773e-288 891.0
TLS3_k127_4373982_2 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000000000000000001159 220.0
TLS3_k127_4373982_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000000000000000000000000000000000000000000000000000913 195.0
TLS3_k127_4373982_4 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 - 4.1.3.40 0.00000000000000000000000000000000000000000000005562 176.0
TLS3_k127_4373982_5 Peptidase family M23 K08259 - 3.4.24.75 0.000000000000000000000000000000000000000002362 161.0
TLS3_k127_4373982_6 Protein of unknown function (DUF721) - - - 0.00000000000000000000000000000000224 134.0
TLS3_k127_4373982_7 - K18829 - - 0.00000000000000000000000000001363 119.0
TLS3_k127_4380348_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 521.0
TLS3_k127_4380348_1 RESPONSE REGULATOR receiver K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 495.0
TLS3_k127_4380348_2 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008339 459.0
TLS3_k127_4380348_3 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 455.0
TLS3_k127_4380348_4 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 437.0
TLS3_k127_4380348_5 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002234 269.0
TLS3_k127_4380348_6 MlaC protein K07323 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004337 248.0
TLS3_k127_4380348_7 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000000004007 130.0
TLS3_k127_4380348_8 PFAM Sulfate transporter antisigma-factor antagonist STAS K07122 - - 0.0000000000000000000000000001136 119.0
TLS3_k127_4421877_0 Hsp70 protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0 1131.0
TLS3_k127_4421877_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 1.144e-194 612.0
TLS3_k127_4421877_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 428.0
TLS3_k127_4421877_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002501 281.0
TLS3_k127_4421877_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000004697 211.0
TLS3_k127_4421877_5 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000002525 161.0
TLS3_k127_4421877_6 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000001094 130.0
TLS3_k127_4421877_7 -acetyltransferase - - - 0.00000000000000003021 92.0
TLS3_k127_4421877_8 Belongs to the peptidase S8 family - - - 0.0000000000000335 82.0
TLS3_k127_4434198_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.471e-259 800.0
TLS3_k127_4434198_1 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 6.47e-221 715.0
TLS3_k127_4434198_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 325.0
TLS3_k127_4434198_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 301.0
TLS3_k127_4434198_12 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 288.0
TLS3_k127_4434198_13 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003554 279.0
TLS3_k127_4434198_14 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000002716 229.0
TLS3_k127_4434198_15 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000000000000000000003241 218.0
TLS3_k127_4434198_16 Protein of unknown function (DUF2971) - - - 0.0000000000000000000000000000000000000000000000002635 187.0
TLS3_k127_4434198_17 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000000000000000000004415 148.0
TLS3_k127_4434198_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 636.0
TLS3_k127_4434198_3 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 587.0
TLS3_k127_4434198_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 560.0
TLS3_k127_4434198_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 531.0
TLS3_k127_4434198_6 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000984 405.0
TLS3_k127_4434198_7 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 407.0
TLS3_k127_4434198_8 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 372.0
TLS3_k127_4434198_9 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 343.0
TLS3_k127_4464248_0 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 580.0
TLS3_k127_4464248_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 385.0
TLS3_k127_4464248_2 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 318.0
TLS3_k127_4464248_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 306.0
TLS3_k127_4464248_4 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000002688 200.0
TLS3_k127_4464248_5 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000002404 170.0
TLS3_k127_4521653_0 PFAM ATP-binding region, ATPase domain protein K02668 - 2.7.13.3 1.76e-216 683.0
TLS3_k127_4521653_1 PFAM sigma-54 factor interaction domain-containing protein K02667 - - 2.601e-216 681.0
TLS3_k127_4521653_2 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000951 521.0
TLS3_k127_4521653_3 TOBE domain K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 493.0
TLS3_k127_4521653_4 TIGRFAM molybdate ABC transporter K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 360.0
TLS3_k127_4521653_5 molybdenum ABC transporter, periplasmic K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 331.0
TLS3_k127_4521653_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005495 253.0
TLS3_k127_4521653_7 Ami_2 K03806 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000008413 245.0
TLS3_k127_4521653_8 - K06950 - - 0.0000000000000000003167 89.0
TLS3_k127_4521653_9 Addiction module toxin, RelE StbE family K19157 - - 0.00005243 51.0
TLS3_k127_4592055_0 Diguanylate cyclase - - - 0.0 1237.0
TLS3_k127_4592055_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0 1221.0
TLS3_k127_4592055_10 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 389.0
TLS3_k127_4592055_11 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 317.0
TLS3_k127_4592055_12 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 302.0
TLS3_k127_4592055_13 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002073 250.0
TLS3_k127_4592055_14 Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000001414 241.0
TLS3_k127_4592055_15 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000139 212.0
TLS3_k127_4592055_16 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.0000000000000000000000000000000000000000000000000004417 194.0
TLS3_k127_4592055_17 Protein of unknown function (DUF559) - - - 0.000000000000000000000000000000000000000003089 166.0
TLS3_k127_4592055_18 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000001826 113.0
TLS3_k127_4592055_19 PD-(D/E)XK nuclease superfamily - - - 0.000000001953 63.0
TLS3_k127_4592055_2 MgsA AAA+ ATPase C terminal K07478 - - 1.282e-251 780.0
TLS3_k127_4592055_20 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00003359 47.0
TLS3_k127_4592055_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 3.021e-231 722.0
TLS3_k127_4592055_4 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 1.683e-197 620.0
TLS3_k127_4592055_5 Urea ABC transporter, urea binding protein K11959 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009103 603.0
TLS3_k127_4592055_6 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 575.0
TLS3_k127_4592055_7 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 589.0
TLS3_k127_4592055_8 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 500.0
TLS3_k127_4592055_9 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 477.0
TLS3_k127_4592423_0 Bacterial type II/III secretion system short domain K02453 - - 3.115e-259 820.0
TLS3_k127_4592423_1 Type II/IV secretion system protein K02454,K02652 - - 1.844e-256 799.0
TLS3_k127_4592423_10 Type II secretion system (T2SS), protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001423 249.0
TLS3_k127_4592423_11 Prokaryotic N-terminal methylation motif K02459 - - 0.000000000000000000000000000000000000000000000000000000000000000005456 233.0
TLS3_k127_4592423_12 Type II transport protein GspH K02457 - - 0.0000000000000000000000000000000000000000000000000000000000004175 216.0
TLS3_k127_4592423_13 Type II secretion system (T2SS), protein I K02458 - - 0.0000000000000000000000000000000000000000000004266 171.0
TLS3_k127_4592423_14 domain protein - - - 0.000000000000000000000000000000000000000009526 177.0
TLS3_k127_4592423_15 Type II secretion system (T2SS), protein M K02462 - - 0.00000000000000000000000000000000000000001198 160.0
TLS3_k127_4592423_16 general secretion pathway protein K02452 - - 0.00000000000000000000000000000000003898 152.0
TLS3_k127_4592423_17 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.00000000000000000009419 89.0
TLS3_k127_4592423_2 Type II secretion system (T2SS), protein F K02455 - - 1.433e-199 627.0
TLS3_k127_4592423_3 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 2.753e-197 621.0
TLS3_k127_4592423_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 581.0
TLS3_k127_4592423_5 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 521.0
TLS3_k127_4592423_6 GspL periplasmic domain K02461 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 412.0
TLS3_k127_4592423_7 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 368.0
TLS3_k127_4592423_8 Type II secretion system (T2SS), protein N K02463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 356.0
TLS3_k127_4592423_9 Shikimate kinase K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000004208 258.0
TLS3_k127_4608000_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 1.419e-235 731.0
TLS3_k127_4608000_1 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004157 246.0
TLS3_k127_4608000_2 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.00000000000000000000000000000000000000000000000000000000000000335 221.0
TLS3_k127_4608000_3 Transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000000000000000000000007544 219.0
TLS3_k127_4608000_4 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000005059 215.0
TLS3_k127_4608000_5 TIGRFAM iron-sulfur cluster assembly protein IscA K13628 - - 0.000000000000000000000000000000000000000000000000000000106 195.0
TLS3_k127_4608000_6 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000062 178.0
TLS3_k127_4626711_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 5.71e-227 705.0
TLS3_k127_4626711_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 559.0
TLS3_k127_4626711_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 361.0
TLS3_k127_4626711_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 308.0
TLS3_k127_4626711_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 307.0
TLS3_k127_4626711_5 translation initiation factor activity - - - 0.000000000000000000000001357 107.0
TLS3_k127_4643645_0 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 540.0
TLS3_k127_4643645_1 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 331.0
TLS3_k127_4643645_2 Glutathione S-transferase, C-terminal domain K03599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009361 300.0
TLS3_k127_4649891_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 537.0
TLS3_k127_4649891_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005002 353.0
TLS3_k127_4649891_2 - - - - 0.00000000008036 68.0
TLS3_k127_4649891_3 Uncharacterized protein conserved in bacteria (DUF2331) - - - 0.0001172 44.0
TLS3_k127_4651788_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 516.0
TLS3_k127_4651788_1 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000001047 228.0
TLS3_k127_46595_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 1.457e-310 956.0
TLS3_k127_46595_1 PFAM tRNA synthetase class II (D K and N) K04567 - 6.1.1.6 2.369e-286 884.0
TLS3_k127_46595_2 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006523 347.0
TLS3_k127_46595_3 Protein of unknown function (DUF2892) - - - 0.0000000000000000006731 90.0
TLS3_k127_46595_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00055 46.0
TLS3_k127_4670631_0 PFAM Type II secretion system F domain K02455,K12278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 559.0
TLS3_k127_4670631_1 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 458.0
TLS3_k127_4677078_0 Four helix bundle sensory module for signal transduction K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 415.0
TLS3_k127_4677078_1 Chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000987 240.0
TLS3_k127_4677078_2 PFAM Chemotaxis methyl-accepting receptor, signalling K03406 - - 0.0000000000000002797 79.0
TLS3_k127_46863_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.0 1097.0
TLS3_k127_46863_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 6.308e-243 755.0
TLS3_k127_46863_10 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000000000000003598 102.0
TLS3_k127_46863_11 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.000000000000000000002883 95.0
TLS3_k127_46863_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 571.0
TLS3_k127_46863_3 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 464.0
TLS3_k127_46863_4 lytic transglycosylase activity K08306,K08308,K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031225,GO:0031975,GO:0033554,GO:0034599,GO:0042221,GO:0042597,GO:0043170,GO:0044425,GO:0044462,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0061783,GO:0070887,GO:0071236,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 391.0
TLS3_k127_46863_5 Periplasmic binding protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002159 258.0
TLS3_k127_46863_6 TIGRFAM succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.0000000000000000000000000000000000000000000000000002411 187.0
TLS3_k127_46863_7 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000000000001454 141.0
TLS3_k127_46863_8 Succinate dehydrogenase, hydrophobic K00242 - - 0.0000000000000000000000000000001205 132.0
TLS3_k127_46863_9 4Fe-4S binding domain protein - - - 0.000000000000000000000008626 102.0
TLS3_k127_4689347_0 nitrite sulfite reductase hemoprotein beta-component ferrodoxin domain protein K00381,K00392 - 1.8.1.2,1.8.7.1 7e-323 1000.0
TLS3_k127_4689347_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 2.601e-272 843.0
TLS3_k127_4689347_10 Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000009739 219.0
TLS3_k127_4689347_2 Elongation factor Tu GTP binding domain K00956 - 2.7.7.4 3.158e-227 708.0
TLS3_k127_4689347_3 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 597.0
TLS3_k127_4689347_4 LysR substrate binding domain K13634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 515.0
TLS3_k127_4689347_5 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 417.0
TLS3_k127_4689347_6 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 394.0
TLS3_k127_4689347_7 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 301.0
TLS3_k127_4689347_8 Membrane-bound serine protease (ClpP class) K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005699 273.0
TLS3_k127_4689347_9 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000131 225.0
TLS3_k127_4775387_0 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 425.0
TLS3_k127_4775387_1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 323.0
TLS3_k127_4775387_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000004174 162.0
TLS3_k127_4816321_0 PFAM cytochrome c oxidase subunit I K00404 - 1.9.3.1 4.958e-281 867.0
TLS3_k127_4816321_1 TIGRFAM cytochrome c oxidase accessory protein CcoG - - - 3.651e-252 786.0
TLS3_k127_4816321_10 - - - - 0.0000000000000000000000000000000000001516 146.0
TLS3_k127_4816321_11 - - - - 0.0000000000000000000000000008018 115.0
TLS3_k127_4816321_12 ThiS family K03154 - - 0.000000000000000000001488 95.0
TLS3_k127_4816321_13 Cbb3-type cytochrome oxidase component FixQ - - - 0.000000000000000000005169 93.0
TLS3_k127_4816321_2 Anthranilate synthase component I domain protein K01665,K13950 - 2.6.1.85 2.295e-194 614.0
TLS3_k127_4816321_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 479.0
TLS3_k127_4816321_4 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 477.0
TLS3_k127_4816321_5 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 427.0
TLS3_k127_4816321_6 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 362.0
TLS3_k127_4816321_7 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 297.0
TLS3_k127_4816321_8 FixH - - - 0.0000000000000000000000000000000000000000000000000000000000000000004691 231.0
TLS3_k127_4816321_9 outer membrane protein W K07275 - - 0.000000000000000000000000000000000000000000000000000002496 198.0
TLS3_k127_4899719_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 4.073e-220 687.0
TLS3_k127_4899719_1 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 4.437e-201 634.0
TLS3_k127_4899719_2 Protein of unknown function (DUF615) K09889 - - 0.000000000000000000000000000000000000000000000000000000000000000002174 230.0
TLS3_k127_4899719_3 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000001336 230.0
TLS3_k127_4899719_4 Hemerythrin-like metal-binding protein - - - 0.0000000000000000000009378 100.0
TLS3_k127_4899719_5 ISXO2-like transposase domain - - - 0.00000000005293 64.0
TLS3_k127_4934238_0 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 542.0
TLS3_k127_4934238_1 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 472.0
TLS3_k127_4934238_2 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 308.0
TLS3_k127_4934238_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 300.0
TLS3_k127_4934238_4 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004464 245.0
TLS3_k127_4934238_5 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000002449 225.0
TLS3_k127_4934238_6 Thermostable hemolysin - - - 0.00000000000000000000000000000000000000000000000000004652 195.0
TLS3_k127_4934238_7 - - - - 0.00000000000000000000000009126 108.0
TLS3_k127_4934238_8 RNA polymerase sigma K03087 - - 0.00000000000000000003198 98.0
TLS3_k127_4934238_9 Winged helix-turn-helix transcription repressor, HrcA DNA-binding K03705 - - 0.00000000000000001165 83.0
TLS3_k127_5142678_0 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 4.503e-204 638.0
TLS3_k127_5142678_1 Soluble lytic murein transglycosylase L domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007982 278.0
TLS3_k127_5142678_2 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000002167 164.0
TLS3_k127_5184426_0 Molydopterin dinucleotide binding domain - - - 6.976e-241 767.0
TLS3_k127_5184426_1 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007024 273.0
TLS3_k127_5184426_2 cyclic nucleotide-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000009859 245.0
TLS3_k127_5184426_3 PFAM Tetratricopeptide repeat K07126 - - 0.0000000000000000000000000000007991 126.0
TLS3_k127_5203785_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 5.014e-252 801.0
TLS3_k127_5203785_1 Phospholipase A1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 403.0
TLS3_k127_5203785_2 mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 376.0
TLS3_k127_5203785_3 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002108 263.0
TLS3_k127_5203785_4 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000008106 241.0
TLS3_k127_5203785_5 Protein of unknown function (DUF3106) - - - 0.00000000000000000000000000000002607 131.0
TLS3_k127_5203785_6 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.000000000000000000000589 96.0
TLS3_k127_5203785_8 Por secretion system C-terminal sorting domain-containing protein - - - 0.00000005064 62.0
TLS3_k127_5209532_0 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 3.503e-209 654.0
TLS3_k127_5209532_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009572 569.0
TLS3_k127_5209532_10 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000000000001603 93.0
TLS3_k127_5209532_11 COG2853 Surface lipoprotein K04754 - - 0.0007961 44.0
TLS3_k127_5209532_2 Pyridoxal-phosphate dependent enzyme K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 525.0
TLS3_k127_5209532_3 pfkB family carbohydrate kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 508.0
TLS3_k127_5209532_4 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 391.0
TLS3_k127_5209532_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 376.0
TLS3_k127_5209532_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000000000004381 173.0
TLS3_k127_5209532_7 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000005079 134.0
TLS3_k127_5209532_8 Pfam:DUF1049 K08992 - - 0.00000000000000000000000000003715 119.0
TLS3_k127_5209532_9 TIGRFAM addiction module toxin, RelE StbE family K19092 - - 0.00000000000000000000000004138 111.0
TLS3_k127_5239054_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 4.276e-265 820.0
TLS3_k127_5239054_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 1.726e-197 618.0
TLS3_k127_5239054_10 - - - - 0.00000001472 55.0
TLS3_k127_5239054_11 Hemerythrin HHE cation binding domain K07216 - - 0.0000002742 57.0
TLS3_k127_5239054_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 565.0
TLS3_k127_5239054_3 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 329.0
TLS3_k127_5239054_4 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 338.0
TLS3_k127_5239054_5 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001242 275.0
TLS3_k127_5239054_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000001737 213.0
TLS3_k127_5239054_7 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000000000000002868 185.0
TLS3_k127_5239054_8 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000006996 197.0
TLS3_k127_5239054_9 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000000000000469 158.0
TLS3_k127_524048_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1067.0
TLS3_k127_524048_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 2.563e-238 744.0
TLS3_k127_524048_11 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000003202 140.0
TLS3_k127_524048_12 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000000000004316 137.0
TLS3_k127_524048_13 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000000016 82.0
TLS3_k127_524048_14 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000216 69.0
TLS3_k127_524048_15 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000001842 56.0
TLS3_k127_524048_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 6.382e-235 739.0
TLS3_k127_524048_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 609.0
TLS3_k127_524048_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 508.0
TLS3_k127_524048_5 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008735 426.0
TLS3_k127_524048_6 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 391.0
TLS3_k127_524048_7 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707 303.0
TLS3_k127_524048_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007377 268.0
TLS3_k127_524048_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000145 257.0
TLS3_k127_5294200_0 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 413.0
TLS3_k127_5294200_1 single-stranded DNA 5'-3' exodeoxyribonuclease activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 378.0
TLS3_k127_5294200_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 342.0
TLS3_k127_5294200_3 Molybdenum Cofactor Synthesis C K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000009098 256.0
TLS3_k127_5294200_4 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006803 250.0
TLS3_k127_5294200_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000005856 114.0
TLS3_k127_5294200_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000006692 81.0
TLS3_k127_5295055_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K18138 - - 0.0 1395.0
TLS3_k127_5295055_1 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1144.0
TLS3_k127_5295055_10 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 443.0
TLS3_k127_5295055_11 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 436.0
TLS3_k127_5295055_12 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 413.0
TLS3_k127_5295055_13 Outer membrane efflux protein K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 385.0
TLS3_k127_5295055_14 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 371.0
TLS3_k127_5295055_15 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 371.0
TLS3_k127_5295055_16 Flavodoxin-like fold K19784 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 319.0
TLS3_k127_5295055_17 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 312.0
TLS3_k127_5295055_18 Domain of unknown function (DUF1956) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 290.0
TLS3_k127_5295055_19 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008679 267.0
TLS3_k127_5295055_2 repeat-containing protein - - - 1.405e-222 713.0
TLS3_k127_5295055_20 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002332 268.0
TLS3_k127_5295055_21 Domain of unknown function (DUF3369) - - - 0.00000000000000000000000000000000000000000000000000000000000000001964 243.0
TLS3_k127_5295055_22 PAS fold - - - 0.000000000000000000000000000000000000000000000000004137 186.0
TLS3_k127_5295055_23 Pfam Glutaredoxin - - - 0.0000000000000000000000000000000000000000000000008279 181.0
TLS3_k127_5295055_24 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000002581 170.0
TLS3_k127_5295055_25 Ribosomal protein L31 K02909 - - 0.000000000000000000000000000000004933 129.0
TLS3_k127_5295055_26 STAS domain K20978 - - 0.000000000000000000001809 97.0
TLS3_k127_5295055_27 Hemerythrin HHE cation binding domain K07216 - - 0.00000000000000000004955 95.0
TLS3_k127_5295055_29 Transposase IS200 like K07491 - - 0.000000000007355 74.0
TLS3_k127_5295055_3 Belongs to the peptidase M16 family K07263 - - 5.848e-221 693.0
TLS3_k127_5295055_4 Peptidase family M48 - - - 4.056e-211 666.0
TLS3_k127_5295055_5 ABC-type uncharacterized transport system - - - 2.099e-203 641.0
TLS3_k127_5295055_6 SMART chemotaxis sensory transducer - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 593.0
TLS3_k127_5295055_7 Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 589.0
TLS3_k127_5295055_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 522.0
TLS3_k127_5295055_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 513.0
TLS3_k127_5307687_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 320.0
TLS3_k127_5307687_1 PFAM ferric-uptake regulator K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009751 258.0
TLS3_k127_5307687_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000001185 123.0
TLS3_k127_5307687_3 FeoA K04758 - - 0.00000000000000000000000000004852 119.0
TLS3_k127_5316413_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.384e-297 916.0
TLS3_k127_5316413_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000000000000000000000000000000002302 238.0
TLS3_k127_5316413_2 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.00000000000000000000000000000000000000000000000000000000000001101 221.0
TLS3_k127_5316413_3 - - - - 0.0000000000000000000153 93.0
TLS3_k127_5336552_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1173.0
TLS3_k127_5336552_1 Tetrapyrrole (Corrin/Porphyrin) Methylases K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 387.0
TLS3_k127_5336552_2 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001834 241.0
TLS3_k127_5336552_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000000000009008 151.0
TLS3_k127_5336552_4 Maf-like protein K06287 - - 0.00000000000000000000007796 98.0
TLS3_k127_5365456_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1112.0
TLS3_k127_5365456_1 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 521.0
TLS3_k127_5365456_2 Transposase IS116 IS110 IS902 family protein K07486 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 417.0
TLS3_k127_5365456_3 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000002031 110.0
TLS3_k127_5365456_4 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 0.000000000001191 69.0
TLS3_k127_5378301_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 5.281e-291 903.0
TLS3_k127_5378301_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 2.482e-246 764.0
TLS3_k127_5378301_2 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 522.0
TLS3_k127_5378301_3 Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 418.0
TLS3_k127_5378301_4 Prokaryotic cytochrome b561 K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000007273 229.0
TLS3_k127_5378301_5 Hydrogenase urease accessory protein K03192 - - 0.00000000000000000000000000000000000000000000000000000009924 201.0
TLS3_k127_5378301_6 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000000000000000000000000000002459 185.0
TLS3_k127_5378301_7 Hydrogenase maturation protease K03605 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000003629 179.0
TLS3_k127_5378301_8 Single cache domain 3 - - - 0.000000000000000000000000000000000000000284 169.0
TLS3_k127_5378301_9 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000000003484 114.0
TLS3_k127_5424335_0 Polysaccharide biosynthesis/export protein - - - 2.139e-223 708.0
TLS3_k127_5424335_1 COG3524 Capsule polysaccharide export protein K10107 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 409.0
TLS3_k127_5424335_2 PFAM ABC transporter related K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 327.0
TLS3_k127_5424335_3 Transport permease protein K09688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 293.0
TLS3_k127_5424335_4 Glycosyl transferase, family 2 K20444 - - 0.0000000000000000000000000001249 119.0
TLS3_k127_5461140_0 glycosyl transferase family 2 K20444 - - 3.884e-233 743.0
TLS3_k127_5461140_1 pfam abc K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 470.0
TLS3_k127_5461140_2 O-linked N-acetylglucosamine transferase, SPINDLY family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 415.0
TLS3_k127_5461140_3 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002668 263.0
TLS3_k127_5461140_4 methyltransferase activity K00574,K12240,K18534,K19620,K20444 - 2.1.1.295,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000005809 264.0
TLS3_k127_5461140_5 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001055 249.0
TLS3_k127_5461140_6 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000004028 158.0
TLS3_k127_5461140_7 Tetratricopeptide repeat - - - 0.000000000002195 72.0
TLS3_k127_5470149_0 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 445.0
TLS3_k127_5470149_1 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 338.0
TLS3_k127_5470149_2 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000002236 245.0
TLS3_k127_55105_0 PFAM chemotaxis sensory transducer K03776 - - 3.606e-311 967.0
TLS3_k127_55105_1 PFAM ATP-binding region ATPase domain protein K03407 - 2.7.13.3 9.154e-253 793.0
TLS3_k127_55105_10 PFAM OmpA MotB domain protein K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000789 443.0
TLS3_k127_55105_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 447.0
TLS3_k127_55105_12 Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) K03414 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 353.0
TLS3_k127_55105_13 Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 296.0
TLS3_k127_55105_14 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004157 252.0
TLS3_k127_55105_15 PFAM response regulator receiver K03413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000208 236.0
TLS3_k127_55105_16 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000477 246.0
TLS3_k127_55105_17 Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02403 - - 0.000000000000000000000000000000000000000000006665 169.0
TLS3_k127_55105_2 SMART GGDEF domain containing protein - - - 3.197e-234 741.0
TLS3_k127_55105_3 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 598.0
TLS3_k127_55105_4 SMART CheW domain protein K03415 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 569.0
TLS3_k127_55105_5 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 562.0
TLS3_k127_55105_6 SMART CheW domain protein K03415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 537.0
TLS3_k127_55105_7 SMART chemotaxis sensory transducer - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 540.0
TLS3_k127_55105_8 PFAM MotA TolQ ExbB proton channel K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 474.0
TLS3_k127_55105_9 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 463.0
TLS3_k127_5517976_0 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 5.909e-310 958.0
TLS3_k127_5517976_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 8.764e-310 953.0
TLS3_k127_5517976_2 PFAM Carbamoyl-phosphate synthase L chain K01959 - 6.4.1.1 2.365e-274 847.0
TLS3_k127_5517976_3 Enoyl-CoA hydratase isomerase K19640 - - 1.315e-199 634.0
TLS3_k127_5517976_4 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 541.0
TLS3_k127_5517976_5 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009897 486.0
TLS3_k127_5517976_6 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 488.0
TLS3_k127_5525972_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.748e-305 955.0
TLS3_k127_5525972_1 chemotaxis K03406 - - 3.022e-301 930.0
TLS3_k127_5525972_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 8.589e-286 881.0
TLS3_k127_5525972_3 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 417.0
TLS3_k127_5525972_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 306.0
TLS3_k127_5525972_5 Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000003311 214.0
TLS3_k127_5525972_6 hydrogenase maturation protease - - - 0.0000000000000000000000000000000000000000000001378 176.0
TLS3_k127_5544214_0 MltA specific insert domain K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 599.0
TLS3_k127_5544214_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 574.0
TLS3_k127_5544214_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 335.0
TLS3_k127_5544214_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 317.0
TLS3_k127_5544214_4 ApaG domain K06195 - - 0.0000000000000000000000000000000000000000000000000000000009773 206.0
TLS3_k127_566013_0 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.0 1513.0
TLS3_k127_566013_1 ABC transporter K06020 - 3.6.3.25 0.0 1007.0
TLS3_k127_566013_10 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000004642 173.0
TLS3_k127_566013_11 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000000000000000000001539 151.0
TLS3_k127_566013_12 Oxidoreductase FAD-binding domain protein K00523 - 1.17.1.1 0.0000000000000000000000000000004057 125.0
TLS3_k127_566013_13 AAA domain - - - 0.000000000000000004623 86.0
TLS3_k127_566013_15 Selenoprotein, putative - - - 0.000000001731 71.0
TLS3_k127_566013_16 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000003873 55.0
TLS3_k127_566013_2 PFAM Carbon starvation protein CstA K06200 - - 1.76e-310 958.0
TLS3_k127_566013_3 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 3.007e-250 784.0
TLS3_k127_566013_4 PFAM Lipocalin family protein K03098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004966 264.0
TLS3_k127_566013_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004035 256.0
TLS3_k127_566013_6 PIN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001279 234.0
TLS3_k127_566013_7 Putative member of DMT superfamily (DUF486) K09922 - - 0.00000000000000000000000000000000000000000000000000000000000009821 214.0
TLS3_k127_566013_8 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000002104 209.0
TLS3_k127_566013_9 Protein of unknown function DUF262 K00655,K07451 - 2.3.1.51 0.000000000000000000000000000000000000000000000000001701 186.0
TLS3_k127_5738553_0 alpha-glucan phosphorylase K00688 - 2.4.1.1 0.0 1378.0
TLS3_k127_5738553_1 Starch synthase catalytic domain K00703 - 2.4.1.21 0.0000000000000000003795 88.0
TLS3_k127_5747094_0 Belongs to the catalase family K03781 - 1.11.1.6 1.18e-289 893.0
TLS3_k127_5747094_1 EamA-like transporter family K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 416.0
TLS3_k127_5747094_2 SpoIIAA-like - - - 0.000000000000000000000000000000000000000000000000000000000004838 208.0
TLS3_k127_5747094_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000000006774 101.0
TLS3_k127_5759991_0 PFAM aminotransferase class I and II K14267 - 2.6.1.17 2.156e-219 686.0
TLS3_k127_5759991_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 1.995e-211 661.0
TLS3_k127_5759991_2 PFAM type II secretion system protein E K02670 - - 1.084e-198 624.0
TLS3_k127_5759991_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009743 511.0
TLS3_k127_5759991_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 444.0
TLS3_k127_5759991_5 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 419.0
TLS3_k127_5759991_6 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 293.0
TLS3_k127_5759991_7 Transposase IS116 IS110 IS902 family protein K07486 - - 0.00000000000000000000000000000000000000000000000004382 179.0
TLS3_k127_5759991_8 - - - - 0.0000000000000000000000000000000000000000000000005157 179.0
TLS3_k127_5827045_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 1.896e-207 646.0
TLS3_k127_5827045_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007344 495.0
TLS3_k127_5827045_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 464.0
TLS3_k127_5827045_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000008036 172.0
TLS3_k127_5907742_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 2.618e-250 774.0
TLS3_k127_5907742_1 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 5.926e-212 665.0
TLS3_k127_5907742_2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 595.0
TLS3_k127_5907742_3 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 392.0
TLS3_k127_5907742_4 Appr-1-p processing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008543 306.0
TLS3_k127_5907742_5 serine protease K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000009231 231.0
TLS3_k127_5907742_6 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000000000000000000003604 141.0
TLS3_k127_5907742_7 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000001193 134.0
TLS3_k127_5918780_0 PFAM Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase - - - 1.777e-230 722.0
TLS3_k127_5918780_1 Indole-3-glycerol phosphate synthase K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.0000000000000000000000000000000000006349 140.0
TLS3_k127_5954919_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 2248.0
TLS3_k127_5954919_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07673 - 2.7.13.3 9.286e-231 731.0
TLS3_k127_5954919_2 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 596.0
TLS3_k127_5954919_3 PFAM NnrS family protein K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005892 560.0
TLS3_k127_5954919_4 COG2223 Nitrate nitrite transporter K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 531.0
TLS3_k127_5954919_5 Transporter K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 455.0
TLS3_k127_5954919_6 helix_turn_helix, Lux Regulon K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 306.0
TLS3_k127_5954919_7 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000005897 256.0
TLS3_k127_5954919_8 TIGRFAM transcriptional regulator, Rrf2 family K13771 - - 0.00000000000000000000000000000000000000000000000000000000005182 208.0
TLS3_k127_5954919_9 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000001135 94.0
TLS3_k127_599757_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1729.0
TLS3_k127_599757_1 Virulence factor membrane-bound polymerase, C-terminal - - - 3.112e-220 698.0
TLS3_k127_599757_10 Sulfurtransferase - - - 0.00000000000000000000000006747 108.0
TLS3_k127_599757_11 CsbD-like - - - 0.0000000000000000004492 87.0
TLS3_k127_599757_2 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 507.0
TLS3_k127_599757_3 ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 373.0
TLS3_k127_599757_4 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 366.0
TLS3_k127_599757_5 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004423 274.0
TLS3_k127_599757_6 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000000000000000000000000000007722 236.0
TLS3_k127_599757_7 Bacterial SH3 domain - - - 0.0000000000000000000000000000000000000000000000000000001913 205.0
TLS3_k127_599757_8 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000000000383 142.0
TLS3_k127_599757_9 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000007114 138.0
TLS3_k127_6015819_0 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 421.0
TLS3_k127_6015819_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 305.0
TLS3_k127_6015819_2 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000000000000000000000000000000000000000000000001135 219.0
TLS3_k127_6022551_0 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 513.0
TLS3_k127_6022551_1 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 315.0
TLS3_k127_6022551_2 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000000000000000000000008285 196.0
TLS3_k127_6022551_3 Membrane fusogenic activity K09806 - - 0.0000000000000000000000002591 107.0
TLS3_k127_6041679_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 3.254e-210 659.0
TLS3_k127_6041679_1 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 1.028e-205 642.0
TLS3_k127_6041679_2 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009853 593.0
TLS3_k127_6041679_3 Transposase IS116 IS110 IS902 family protein K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008679 550.0
TLS3_k127_6041679_4 Protein of unknown function (DUF3014) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 287.0
TLS3_k127_6041679_5 - - - - 0.0000000000000000000000000000000000000000000000000000008898 197.0
TLS3_k127_6041679_6 Rhodanese Homology Domain K06917 - - 0.00000000000000000000000000000000000000000000000000001958 191.0
TLS3_k127_61075_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 536.0
TLS3_k127_61075_1 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000000001034 186.0
TLS3_k127_61075_3 ABC transporter - - - 0.0000000000000000009715 85.0
TLS3_k127_6128693_0 Hemolysin activation secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 344.0
TLS3_k127_6128693_1 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000006023 248.0
TLS3_k127_6128693_2 FecR protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004823 261.0
TLS3_k127_6176730_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.99.6 3.954e-228 720.0
TLS3_k127_6176730_1 Hydrogenase formation hypA family K04654 - - 9.056e-209 655.0
TLS3_k127_6176730_10 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000000000009614 109.0
TLS3_k127_6176730_11 Hydrogenase expression formation protein K03605 - - 0.00000000000000000001312 95.0
TLS3_k127_6176730_12 Alpha-amylase domain - - - 0.0000000000000001441 94.0
TLS3_k127_6176730_13 HupH hydrogenase expression protein, C-terminal conserved region K03618 - - 0.00000000000007911 78.0
TLS3_k127_6176730_2 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 586.0
TLS3_k127_6176730_3 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 357.0
TLS3_k127_6176730_4 Enoyl-CoA hydratase isomerase K19640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 313.0
TLS3_k127_6176730_5 Ni,Fe-hydrogenase I large subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007171 283.0
TLS3_k127_6176730_6 Hydrogenase K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003349 265.0
TLS3_k127_6176730_7 Hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000000000000000000000000000000000002543 231.0
TLS3_k127_6176730_8 HupE / UreJ protein K03192 - - 0.000000000000000000000000000000000000000000000003289 179.0
TLS3_k127_6176730_9 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000000000000000004228 145.0
TLS3_k127_6218608_0 Sodium:solute symporter family - - - 7.141e-212 668.0
TLS3_k127_6218608_1 TIGRFAM phosphate regulon sensor kinase PhoR K07636 - 2.7.13.3 9.308e-203 638.0
TLS3_k127_6218608_2 Two component transcriptional regulator PhoB, winged helix family K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 385.0
TLS3_k127_6218608_3 Uncharacterized protein family, UPF0114 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 283.0
TLS3_k127_6218608_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000227 256.0
TLS3_k127_6239967_0 Histidine kinase K11527 - 2.7.13.3 2.552e-293 942.0
TLS3_k127_6239967_1 Histidine kinase K11527 - 2.7.13.3 1.558e-253 798.0
TLS3_k127_6239967_2 His Kinase A (phosphoacceptor) domain - - - 3.022e-195 625.0
TLS3_k127_6239967_3 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 537.0
TLS3_k127_6239967_4 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000105 219.0
TLS3_k127_6239967_5 Protein of unknown function (DUF2846) - - - 0.00009787 45.0
TLS3_k127_6275724_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 1.225e-262 819.0
TLS3_k127_6275724_1 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 461.0
TLS3_k127_6275724_2 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000176 250.0
TLS3_k127_6275724_3 Small Multidrug Resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000009873 216.0
TLS3_k127_6275724_4 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000002698 209.0
TLS3_k127_6277970_0 elongation factor Tu domain 2 protein K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 527.0
TLS3_k127_6277970_1 Protein of unknown function (DUF560) - - - 0.0000000000000000000000000000000000000000000000000766 199.0
TLS3_k127_6277970_2 PFAM type II and III secretion system protein K02666 - - 0.000000000000000000000006516 118.0
TLS3_k127_6277970_3 PFAM FecR protein - - - 0.00000000000000000000003943 117.0
TLS3_k127_6323607_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 551.0
TLS3_k127_6323607_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008086 457.0
TLS3_k127_6323607_2 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 431.0
TLS3_k127_6323607_3 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002023 275.0
TLS3_k127_6323607_4 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000000244 173.0
TLS3_k127_6323607_5 PFAM Carbohydrate-selective porin OprB K07267 - - 0.00000000000000000000001407 106.0
TLS3_k127_6328291_0 Pfam:KaiC K08482 - - 5.304e-235 739.0
TLS3_k127_6328291_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 300.0
TLS3_k127_6328291_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001885 274.0
TLS3_k127_6328291_3 KaiB domain K08481 - - 0.0000000000000000000000000000001278 133.0
TLS3_k127_6380014_0 Belongs to the peptidase S16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 332.0
TLS3_k127_6380014_1 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000001988 216.0
TLS3_k127_6380014_2 ATPase (AAA superfamily K07133 - - 0.00000000000000000000000000000000000001623 161.0
TLS3_k127_6382753_0 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.0 1377.0
TLS3_k127_6382753_1 Putative diguanylate phosphodiesterase - - - 0.0 1140.0
TLS3_k127_6382753_10 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001715 274.0
TLS3_k127_6382753_11 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000003489 192.0
TLS3_k127_6382753_12 Hemerythrin-like metal-binding protein - - - 0.00000000000000003513 88.0
TLS3_k127_6382753_13 - - - - 0.000000000001128 70.0
TLS3_k127_6382753_2 AAA domain K16898 - 3.6.4.12 9.4e-323 997.0
TLS3_k127_6382753_3 Ammonium Transporter Family K03320,K06580 - - 6.704e-236 733.0
TLS3_k127_6382753_4 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009719 464.0
TLS3_k127_6382753_5 Flagellar Assembly Protein A K09749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009175 464.0
TLS3_k127_6382753_6 ATPase MipZ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 368.0
TLS3_k127_6382753_7 MlaA lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 311.0
TLS3_k127_6382753_8 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 293.0
TLS3_k127_6382753_9 SMART band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003401 278.0
TLS3_k127_6390004_0 protein synthesis factor, GTP-binding K06207 - - 1e-323 998.0
TLS3_k127_6396335_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.279e-266 824.0
TLS3_k127_6396335_1 Domain of unknown function DUF21 - - - 3.144e-216 677.0
TLS3_k127_6396335_2 PFAM Type II secretion system F domain K02653 - - 2.456e-214 670.0
TLS3_k127_6396335_3 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 471.0
TLS3_k127_6396335_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 440.0
TLS3_k127_6423225_0 NlpB/DapX lipoprotein K07287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 450.0
TLS3_k127_6423225_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 372.0
TLS3_k127_6423225_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000006658 239.0
TLS3_k127_6423225_3 - - - - 0.000000000000000000000000000000000006582 137.0
TLS3_k127_6520808_0 PFAM EAL domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 556.0
TLS3_k127_6520808_1 SMART ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 499.0
TLS3_k127_6520808_2 Histidine kinase K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000345 286.0
TLS3_k127_6520808_3 Bacterial regulatory proteins, luxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001218 250.0
TLS3_k127_6520808_4 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008402 244.0
TLS3_k127_6520808_5 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000001447 200.0
TLS3_k127_6568870_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 616.0
TLS3_k127_6568870_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 440.0
TLS3_k127_6568870_10 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000000000000000002607 145.0
TLS3_k127_6568870_11 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.0000000000000000000000000000000000003712 141.0
TLS3_k127_6568870_12 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000001378 122.0
TLS3_k127_6568870_13 - - - - 0.00000000000000000009917 90.0
TLS3_k127_6568870_14 Rhodanese domain protein - - - 0.000000000000009395 75.0
TLS3_k127_6568870_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 433.0
TLS3_k127_6568870_3 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 338.0
TLS3_k127_6568870_4 LppC putative lipoprotein K07121 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 332.0
TLS3_k127_6568870_5 RNA pseudouridylate synthase K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001082 285.0
TLS3_k127_6568870_6 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000009678 262.0
TLS3_k127_6568870_7 BON domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004065 242.0
TLS3_k127_6568870_8 TIGRFAM alkylphosphonate utilization operon protein PhnA K06193 - - 0.00000000000000000000000000000000000000000000000000000000000000004552 223.0
TLS3_k127_6568870_9 Uncharacterised protein family UPF0102 K07460 - - 0.0000000000000000000000000000000000000000837 154.0
TLS3_k127_6586254_0 AAA domain K16898 - 3.6.4.12 2.546e-233 732.0
TLS3_k127_6586254_1 Protein conserved in bacteria - - - 9.427e-205 656.0
TLS3_k127_6586254_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008766 602.0
TLS3_k127_6586254_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007189 385.0
TLS3_k127_6586254_4 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004359 248.0
TLS3_k127_6586254_5 Protein of unknown function (DUF1318) K09978 - - 0.00000000000000000000000000000000000000000000000000001793 191.0
TLS3_k127_6586254_6 - - - - 0.000000000000000000000000001926 117.0
TLS3_k127_6586254_7 - - - - 0.00000000000002488 74.0
TLS3_k127_670724_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1115.0
TLS3_k127_670724_1 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007032 546.0
TLS3_k127_670724_10 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000000000000000000000000000001817 158.0
TLS3_k127_670724_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000003534 103.0
TLS3_k127_670724_12 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000002443 98.0
TLS3_k127_670724_2 PFAM peptidase S1 and S6 chymotrypsin Hap K04691,K04772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 535.0
TLS3_k127_670724_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 470.0
TLS3_k127_670724_4 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 419.0
TLS3_k127_670724_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 391.0
TLS3_k127_670724_6 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 367.0
TLS3_k127_670724_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001349 246.0
TLS3_k127_670724_8 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000003471 233.0
TLS3_k127_670724_9 HIT domain K02503 - - 0.0000000000000000000000000000000000000000000000000000000000119 207.0
TLS3_k127_6785542_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 1.128e-241 753.0
TLS3_k127_6785542_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000001103 100.0
TLS3_k127_6785542_2 NfeD-like C-terminal, partner-binding - - - 0.0000000000000000000001932 101.0
TLS3_k127_6785542_3 PFAM band 7 protein - - - 0.00000000001261 65.0
TLS3_k127_6825627_0 Metal-dependent hydrolase HDOD - - - 2.951e-235 750.0
TLS3_k127_6825627_1 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 608.0
TLS3_k127_6825627_2 Fungalysin/Thermolysin Propeptide Motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 513.0
TLS3_k127_6825627_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 445.0
TLS3_k127_6825627_4 SMART serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 436.0
TLS3_k127_6825627_5 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 325.0
TLS3_k127_6825627_6 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000000000000005504 185.0
TLS3_k127_6901868_0 PFAM peptidase M17 leucyl aminopeptidase domain protein K01255 - 3.4.11.1 4.936e-250 779.0
TLS3_k127_6901868_1 PFAM AIR synthase related protein domain protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 575.0
TLS3_k127_6901868_10 Sel1-like repeats. - - - 0.0000000000000000000000000000001271 129.0
TLS3_k127_6901868_11 Hemerythrin-like metal-binding protein - - - 0.00000000000000000000402 98.0
TLS3_k127_6901868_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 510.0
TLS3_k127_6901868_3 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 474.0
TLS3_k127_6901868_4 TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 405.0
TLS3_k127_6901868_5 tRNA (guanine-N7-)-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 339.0
TLS3_k127_6901868_6 Bacterial dnaA protein K10763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 310.0
TLS3_k127_6901868_7 PFAM lipolytic protein G-D-S-L family K01073 - 3.1.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 295.0
TLS3_k127_6901868_8 PFAM RNA-binding S4 K04762 - - 0.00000000000000000000000000000000000000000001813 166.0
TLS3_k127_6901868_9 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000000000000000000004973 132.0
TLS3_k127_6904399_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 575.0
TLS3_k127_6904399_1 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 471.0
TLS3_k127_6904399_2 Chorismate mutase type II K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.000000000000000000000000000000000265 132.0
TLS3_k127_6904399_3 Methionine biosynthesis protein MetW - - - 0.00008138 53.0
TLS3_k127_6905225_0 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 514.0
TLS3_k127_6905225_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001775 276.0
TLS3_k127_6905225_2 Carbonic anhydrase K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001968 272.0
TLS3_k127_6905225_3 Phosphate-starvation-inducible E K13256 - - 0.00000000000000000000000000000000000000000000000000001369 192.0
TLS3_k127_6905225_4 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.000000000000000000000000000004492 119.0
TLS3_k127_6924178_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 5.65e-310 955.0
TLS3_k127_6924178_1 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 586.0
TLS3_k127_6924178_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 462.0
TLS3_k127_6924178_3 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000001715 232.0
TLS3_k127_6924178_4 - - - - 0.000000000000000000000000000000000000000000000000001513 190.0
TLS3_k127_6924178_5 - - - - 0.00000000000000008317 85.0
TLS3_k127_6946836_0 Domain of unknown function DUF87 K06915 - - 3.198e-247 771.0
TLS3_k127_6946836_1 Tetratricopeptide repeats - - - 1.653e-217 689.0
TLS3_k127_6946836_2 VirC1 protein K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 304.0
TLS3_k127_6953098_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0 1897.0
TLS3_k127_6953098_1 Fumarate reductase flavoprotein C-term K00394 - 1.8.99.2 0.0 1294.0
TLS3_k127_6953098_10 Nitrite and sulphite reductase 4Fe-4S domain K11180 - 1.8.99.5 1.434e-267 825.0
TLS3_k127_6953098_11 Citrate transporter - - - 2.506e-267 837.0
TLS3_k127_6953098_12 PUA-like domain K00958 - 2.7.7.4 1.531e-239 743.0
TLS3_k127_6953098_13 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 2.944e-233 722.0
TLS3_k127_6953098_14 Polysulphide reductase, NrfD K00185 - - 7.354e-201 630.0
TLS3_k127_6953098_15 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009888 534.0
TLS3_k127_6953098_16 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 522.0
TLS3_k127_6953098_17 4Fe-4S binding domain K21308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 507.0
TLS3_k127_6953098_18 PFAM Flavocytochrome c sulphide dehydrogenase, flavin-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 501.0
TLS3_k127_6953098_19 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 485.0
TLS3_k127_6953098_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1231.0
TLS3_k127_6953098_20 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 462.0
TLS3_k127_6953098_21 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 455.0
TLS3_k127_6953098_22 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008687 424.0
TLS3_k127_6953098_23 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 413.0
TLS3_k127_6953098_24 Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 373.0
TLS3_k127_6953098_25 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 357.0
TLS3_k127_6953098_26 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 340.0
TLS3_k127_6953098_27 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 340.0
TLS3_k127_6953098_28 Domain of unknown function (DUF4202) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 338.0
TLS3_k127_6953098_29 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 317.0
TLS3_k127_6953098_3 Sulfate transporter antisigma-factor antagonist STAS - - - 0.0 1148.0
TLS3_k127_6953098_30 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 299.0
TLS3_k127_6953098_31 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 286.0
TLS3_k127_6953098_32 Sulfurtransferase TusA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 280.0
TLS3_k127_6953098_33 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008161 268.0
TLS3_k127_6953098_34 DsrE/DsrF-like family K07235 - - 0.0000000000000000000000000000000000000000000000000000000000000000002822 230.0
TLS3_k127_6953098_35 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000000000000000000001423 224.0
TLS3_k127_6953098_36 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000000000000000000000001425 226.0
TLS3_k127_6953098_37 DsrE/DsrF-like family K07236 - - 0.0000000000000000000000000000000000000000000000000000000000001387 213.0
TLS3_k127_6953098_38 Cas6 Crispr - - - 0.0000000000000000000000000000000000000000000000000000000000001853 222.0
TLS3_k127_6953098_39 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000000000000000000007719 207.0
TLS3_k127_6953098_4 NADH ubiquinone plastoquinone (Complex I) - - - 0.0 1106.0
TLS3_k127_6953098_40 - - - - 0.000000000000000000000000000000000000000000000000000000000629 203.0
TLS3_k127_6953098_41 - - - - 0.00000000000000000000000000000000000000000000000000000007677 198.0
TLS3_k127_6953098_42 - - - - 0.000000000000000000000000000000000000000000000000000001686 197.0
TLS3_k127_6953098_43 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000001265 162.0
TLS3_k127_6953098_44 DsrH like protein K07237 - - 0.0000000000000000000000000000000000000000006851 158.0
TLS3_k127_6953098_45 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000008662 153.0
TLS3_k127_6953098_46 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000000000000000000008473 143.0
TLS3_k127_6953098_47 Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000000000000000000001049 141.0
TLS3_k127_6953098_48 Peptidase family M48 - - - 0.00000000000000000000000000000000002051 137.0
TLS3_k127_6953098_49 Sulfurtransferase TusA K04085 - - 0.000000000000000000000000000000327 123.0
TLS3_k127_6953098_5 Cysteine-rich domain - - - 0.0 1005.0
TLS3_k127_6953098_50 - - - - 0.00000000000000000000000001377 111.0
TLS3_k127_6953098_51 Domain of unknown function DUF302 - - - 0.0000000000000000000000009728 111.0
TLS3_k127_6953098_52 cytochrome - - - 0.0000000000000000000004941 98.0
TLS3_k127_6953098_6 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 3.776e-319 983.0
TLS3_k127_6953098_7 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 1.505e-291 899.0
TLS3_k127_6953098_8 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 1.342e-285 880.0
TLS3_k127_6953098_9 AAA domain K02224 - 6.3.5.11,6.3.5.9 1.554e-272 842.0
TLS3_k127_6960078_0 Recombinase zinc beta ribbon domain - - - 6.112e-243 760.0
TLS3_k127_6960078_1 DNA polymerase alpha chain like domain K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 473.0
TLS3_k127_6960078_2 TIGRFAM Sua5 YciO YrdC YwlC family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 368.0
TLS3_k127_6960078_3 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 362.0
TLS3_k127_6960078_4 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000064 276.0
TLS3_k127_6960078_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009714 263.0
TLS3_k127_6960078_6 Belongs to the UPF0125 (RnfH) family K09801 - - 0.000000000000000000000000000000000006298 140.0
TLS3_k127_6960078_7 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000002454 87.0
TLS3_k127_6960078_8 Recombinase zinc beta ribbon domain - - - 0.00001448 49.0
TLS3_k127_6966210_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.345e-292 906.0
TLS3_k127_6966210_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 7.053e-227 706.0
TLS3_k127_6966210_10 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000002693 66.0
TLS3_k127_6966210_2 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 610.0
TLS3_k127_6966210_3 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 526.0
TLS3_k127_6966210_4 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 363.0
TLS3_k127_6966210_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 288.0
TLS3_k127_6966210_6 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000000000000000003711 227.0
TLS3_k127_6966210_7 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000000000001762 213.0
TLS3_k127_6966210_8 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000003106 199.0
TLS3_k127_6966210_9 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000000000000000009605 136.0
TLS3_k127_6982693_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 1.475e-241 753.0
TLS3_k127_6982693_1 PFAM permease YjgP YjgQ family protein K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 550.0
TLS3_k127_6982693_2 PFAM permease YjgP YjgQ family protein K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 491.0
TLS3_k127_6982693_3 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 386.0
TLS3_k127_6982693_4 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 316.0
TLS3_k127_6982693_5 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 304.0
TLS3_k127_6982693_6 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000003734 102.0
TLS3_k127_6982693_7 Protein of unknown function (DUF3096) - - - 0.000000000003279 70.0
TLS3_k127_7062420_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2545.0
TLS3_k127_7062420_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2464.0
TLS3_k127_7062420_10 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000000000000000000000000000000000000000003856 171.0
TLS3_k127_7062420_11 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000004471 51.0
TLS3_k127_7062420_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 550.0
TLS3_k127_7062420_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008808 394.0
TLS3_k127_7062420_4 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 329.0
TLS3_k127_7062420_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 301.0
TLS3_k127_7062420_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006943 278.0
TLS3_k127_7062420_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008834 264.0
TLS3_k127_7062420_8 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000001315 237.0
TLS3_k127_7062420_9 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000000001758 201.0
TLS3_k127_7066860_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1428.0
TLS3_k127_7066860_1 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 5.335e-222 697.0
TLS3_k127_7066860_2 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 516.0
TLS3_k127_7066860_3 COG2133 Glucose sorbosone dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 516.0
TLS3_k127_7066860_4 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 422.0
TLS3_k127_7066860_5 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 395.0
TLS3_k127_7066860_6 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 391.0
TLS3_k127_7066860_7 chemotaxis, protein - - - 0.0000000000000000000000000000000000000000000000000005241 199.0
TLS3_k127_7066860_8 Ribonucleotide reductase subunit alpha - - - 0.000000000000000000000000000000000004441 142.0
TLS3_k127_7066860_9 transmembrane signaling receptor activity - - - 0.0000000000000000000000000000005228 133.0
TLS3_k127_7081188_0 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 591.0
TLS3_k127_7081188_1 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 441.0
TLS3_k127_7081188_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 418.0
TLS3_k127_7081188_3 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 389.0
TLS3_k127_7081188_4 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 387.0
TLS3_k127_7081188_5 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 340.0
TLS3_k127_7081188_6 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000000000000000175 193.0
TLS3_k127_7081188_8 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000007112 48.0
TLS3_k127_7146584_0 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 0.0 1288.0
TLS3_k127_7146584_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 6.884e-243 754.0
TLS3_k127_7146584_2 Phosphoglucose isomerase K01810 - 5.3.1.9 5.641e-216 676.0
TLS3_k127_7146584_3 Glycosyl hydrolase family 57 - - - 0.0000000000000005603 78.0
TLS3_k127_7149054_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 569.0
TLS3_k127_7149054_1 Transglycosylase SLT domain K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 426.0
TLS3_k127_7149054_2 Bacterial type II and III secretion system protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 295.0
TLS3_k127_7149054_3 PFAM NnrS family protein K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001273 281.0
TLS3_k127_7149054_4 Smr domain - - - 0.00000000000000000000000000000000000000000001765 168.0
TLS3_k127_7149054_5 PFAM Archaeal ATPase - - - 0.000000000000000000000000001543 126.0
TLS3_k127_7179832_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 492.0
TLS3_k127_7179832_1 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 361.0
TLS3_k127_7179832_2 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 358.0
TLS3_k127_7179832_3 HDOD domain - - - 0.00000000000000000000000000000002845 132.0
TLS3_k127_7179832_4 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.000001172 61.0
TLS3_k127_7258682_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.262e-286 889.0
TLS3_k127_7258682_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.066e-262 814.0
TLS3_k127_7258682_2 Arginyl-tRNA synthetase K01887 - 6.1.1.19 2.018e-255 800.0
TLS3_k127_7258682_3 Nitronate monooxygenase K00459 - 1.13.12.16 3.06e-233 726.0
TLS3_k127_7258682_4 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 9.126e-210 653.0
TLS3_k127_7258682_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 376.0
TLS3_k127_7258682_6 DSBA-like thioredoxin domain K03673 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002217 256.0
TLS3_k127_7258682_7 Sporulation related domain - - - 0.000000000000000000000000000000000000000000000000005052 188.0
TLS3_k127_7258682_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000001353 145.0
TLS3_k127_7258682_9 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000004618 53.0
TLS3_k127_7259892_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 1.94e-276 854.0
TLS3_k127_7259892_1 AsmA family K07289 - - 1.764e-247 784.0
TLS3_k127_7259892_10 NusG domain II - - - 0.0000000000000000000000000000000000000000000000000000000004321 207.0
TLS3_k127_7259892_11 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000002009 191.0
TLS3_k127_7259892_12 PFAM sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.00000000000000000000000000000000000000000000000001781 181.0
TLS3_k127_7259892_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 2.74e-203 643.0
TLS3_k127_7259892_3 endonuclease III K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 576.0
TLS3_k127_7259892_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 506.0
TLS3_k127_7259892_5 P-loop ATPase protein family K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 441.0
TLS3_k127_7259892_6 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 378.0
TLS3_k127_7259892_7 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 331.0
TLS3_k127_7259892_8 PFAM Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 297.0
TLS3_k127_7259892_9 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008385 262.0
TLS3_k127_7263040_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 4.899e-274 859.0
TLS3_k127_7263040_1 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 592.0
TLS3_k127_7263040_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007064 377.0
TLS3_k127_7263040_3 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 292.0
TLS3_k127_7263040_4 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000000000000000000001739 208.0
TLS3_k127_7263040_5 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0001614 44.0
TLS3_k127_7323719_0 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147 - - 2.834e-279 869.0
TLS3_k127_7323719_1 Sugar (and other) transporter - - - 5.422e-208 657.0
TLS3_k127_7323719_10 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000002027 244.0
TLS3_k127_7323719_11 polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000001503 194.0
TLS3_k127_7323719_12 SMART Cold shock protein K03704 - - 0.000000000000000000000000000000000003714 137.0
TLS3_k127_7323719_2 NADH flavin K09461 - 1.14.13.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 537.0
TLS3_k127_7323719_3 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 534.0
TLS3_k127_7323719_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 447.0
TLS3_k127_7323719_5 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 399.0
TLS3_k127_7323719_6 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007315 356.0
TLS3_k127_7323719_7 Phospholipase/Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 329.0
TLS3_k127_7323719_8 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 317.0
TLS3_k127_7323719_9 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005711 256.0
TLS3_k127_7327294_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 8.701e-301 941.0
TLS3_k127_7327294_1 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 1.582e-198 627.0
TLS3_k127_7327294_10 Cro/C1-type HTH DNA-binding domain K07727 - - 0.00000000000000000000000000002011 118.0
TLS3_k127_7327294_11 Domain of unknown function (DUF4340) - - - 0.000000000000000000000000004893 121.0
TLS3_k127_7327294_12 - - - - 0.00000000000000000000000117 104.0
TLS3_k127_7327294_13 - - - - 0.0000000004851 63.0
TLS3_k127_7327294_14 - - - - 0.00003106 49.0
TLS3_k127_7327294_2 Pfam:DUF3596 K14059 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 577.0
TLS3_k127_7327294_3 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 564.0
TLS3_k127_7327294_4 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 549.0
TLS3_k127_7327294_5 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 470.0
TLS3_k127_7327294_6 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 333.0
TLS3_k127_7327294_7 Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000003525 257.0
TLS3_k127_7327294_8 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.0000000000000000000000000000000009332 145.0
TLS3_k127_7327294_9 metal-dependent phosphohydrolase HD region K03698 - - 0.000000000000000000000000000000007798 136.0
TLS3_k127_7390915_0 PFAM Peptidase S24 S26A S26B, conserved region K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 432.0
TLS3_k127_7390915_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 334.0
TLS3_k127_7390915_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000004795 167.0
TLS3_k127_7390915_3 Domain of unknown function (DUF4845) - - - 0.0000000000000000000000000000000000002834 143.0
TLS3_k127_7405009_0 Histidine Phosphotransfer domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 448.0
TLS3_k127_7405009_1 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 442.0
TLS3_k127_7405009_2 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 300.0
TLS3_k127_7405009_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000035 236.0
TLS3_k127_7405009_4 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000001349 237.0
TLS3_k127_7405009_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000001415 141.0
TLS3_k127_7420275_0 Glycosyl transferase family 2 K07011,K20444 - - 0.0 1062.0
TLS3_k127_7420275_1 Capsule polysaccharide biosynthesis protein K07266 - - 2.033e-245 775.0
TLS3_k127_7420275_10 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 344.0
TLS3_k127_7420275_11 PFAM Cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004676 282.0
TLS3_k127_7420275_12 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002477 261.0
TLS3_k127_7420275_13 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000002427 220.0
TLS3_k127_7420275_14 helix_turn_helix, Lux Regulon K11712 - - 0.0000000000000000000000000000000000000000000000000000005936 202.0
TLS3_k127_7420275_15 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000005909 191.0
TLS3_k127_7420275_16 PFAM electron transport protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000000000000000008286 184.0
TLS3_k127_7420275_17 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000005459 179.0
TLS3_k127_7420275_18 SMART Cold shock protein K03704 - - 0.0000000000000000000000000000009064 121.0
TLS3_k127_7420275_19 O-methyltransferase activity - - - 0.0000000000000000000003837 108.0
TLS3_k127_7420275_2 Urea ABC transporter, urea binding protein K11959 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000679 571.0
TLS3_k127_7420275_21 - - - - 0.00000000335 69.0
TLS3_k127_7420275_22 Winged helix-turn helix - - - 0.000000008543 56.0
TLS3_k127_7420275_23 Transposase (IS116 IS110 IS902 family) - - - 0.0000003975 53.0
TLS3_k127_7420275_3 PFAM Glycosyl transferase family 2 K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 499.0
TLS3_k127_7420275_4 Capsule polysaccharide biosynthesis protein K07265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 481.0
TLS3_k127_7420275_5 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 408.0
TLS3_k127_7420275_6 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 427.0
TLS3_k127_7420275_7 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008614 404.0
TLS3_k127_7420275_8 Transposase IS116 IS110 IS902 family protein K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 371.0
TLS3_k127_7420275_9 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 318.0
TLS3_k127_7463236_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1068.0
TLS3_k127_7463236_1 - - - - 8.015e-244 758.0
TLS3_k127_7463236_2 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 493.0
TLS3_k127_7463236_3 WLM domain K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004442 260.0
TLS3_k127_7463236_4 Phosphoglycerate mutase family K15640 - - 0.0000000000000001088 87.0
TLS3_k127_7463236_5 phosphoric diester hydrolase activity. It is involved in the biological process described with - - - 0.000003195 60.0
TLS3_k127_7463236_6 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.0003852 45.0
TLS3_k127_7522974_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 475.0
TLS3_k127_7522974_1 Protein of unknown function (DUF3616) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 452.0
TLS3_k127_7522974_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 390.0
TLS3_k127_7522974_3 SMART GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 317.0
TLS3_k127_7683333_0 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 284.0
TLS3_k127_7683333_1 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000911 273.0
TLS3_k127_7683333_2 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.000000000000000000000000000000000000000000000000000000729 200.0
TLS3_k127_7683333_3 TIGRFAM ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.00000000000000000000000000000000006425 133.0
TLS3_k127_7683333_4 Iron-sulphur cluster assembly - - - 0.000000000000000000000001056 108.0
TLS3_k127_7683333_5 Winged helix-turn helix - - - 0.000000008543 56.0
TLS3_k127_7743506_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1646.0
TLS3_k127_7743506_1 Pilus assembly protein K02674 - - 0.0 1082.0
TLS3_k127_7743506_10 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.00000000000000000000000000000000000000000000002174 172.0
TLS3_k127_7743506_11 PilX N-terminal K02673 - - 0.0000000000000000000000000000000000000000000225 168.0
TLS3_k127_7743506_12 Belongs to the UPF0225 family K09858 - - 0.000000000000000000000000000000000000000008363 159.0
TLS3_k127_7743506_13 Transcriptional regulator K07726 - - 0.0000000000000000000000000000000000000001642 152.0
TLS3_k127_7743506_14 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000001026 146.0
TLS3_k127_7743506_15 TIGRFAM Pilus modification type IV, PilV K02671 - - 0.00000000000000000000000000000000000006826 147.0
TLS3_k127_7743506_16 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.000000000000000000000000000001331 125.0
TLS3_k127_7743506_17 Domain of unknown function (DUF4172) - - - 0.00000000000000000000000007538 107.0
TLS3_k127_7743506_18 Type II transport protein GspH K08084 - - 0.000000000000000001176 92.0
TLS3_k127_7743506_19 FecR protein - - - 0.000000000002469 73.0
TLS3_k127_7743506_2 PFAM major facilitator superfamily MFS_1 K19577 - - 1.419e-199 629.0
TLS3_k127_7743506_20 FecR protein - - - 0.00000000002516 77.0
TLS3_k127_7743506_22 Winged helix-turn helix - - - 0.00000002885 56.0
TLS3_k127_7743506_23 Belongs to the 'phage' integrase family - - - 0.0000003592 53.0
TLS3_k127_7743506_3 cytochrome oxidase assembly K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 544.0
TLS3_k127_7743506_4 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 496.0
TLS3_k127_7743506_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 424.0
TLS3_k127_7743506_6 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 387.0
TLS3_k127_7743506_7 Type IV Pilus-assembly protein W K02672 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 332.0
TLS3_k127_7743506_8 PFAM YaeQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008376 252.0
TLS3_k127_7743506_9 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000001792 246.0
TLS3_k127_7771889_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1413.0
TLS3_k127_7771889_1 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 1.928e-281 868.0
TLS3_k127_7771889_10 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 362.0
TLS3_k127_7771889_11 TIGRFAM molybdenum cofactor synthesis K03831 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 331.0
TLS3_k127_7771889_12 Molybdopterin guanine dinucleotide synthesis protein B K03753 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001204 262.0
TLS3_k127_7771889_13 MobA-like NTP transferase domain K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000006206 256.0
TLS3_k127_7771889_14 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000001265 241.0
TLS3_k127_7771889_15 Protein of unknown function (DUF3426) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009676 246.0
TLS3_k127_7771889_16 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000000000000000001359 224.0
TLS3_k127_7771889_17 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.000000000000000000000000000000000000000000000000000000000000148 215.0
TLS3_k127_7771889_18 PFAM CutA1 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000000009552 156.0
TLS3_k127_7771889_19 OmpA family - - - 0.00000000000000000000000000000000000000001143 163.0
TLS3_k127_7771889_2 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 5.011e-197 632.0
TLS3_k127_7771889_20 elongation factor Tu K02358 - - 0.00000000000000000000000000000000005252 133.0
TLS3_k127_7771889_21 FecR protein - - - 0.00000000000000000000000000000007968 130.0
TLS3_k127_7771889_22 STAS domain K06378 - - 0.00000000000000000000000006366 110.0
TLS3_k127_7771889_23 Histidine kinase-like ATPase domain - - - 0.000000000000004912 80.0
TLS3_k127_7771889_24 Winged helix-turn helix - - - 0.00000003978 54.0
TLS3_k127_7771889_26 - - - - 0.000004199 50.0
TLS3_k127_7771889_27 - - - - 0.0006046 44.0
TLS3_k127_7771889_3 MoeA C-terminal region (domain IV) K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009333 612.0
TLS3_k127_7771889_4 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 527.0
TLS3_k127_7771889_5 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 517.0
TLS3_k127_7771889_6 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 519.0
TLS3_k127_7771889_7 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 519.0
TLS3_k127_7771889_8 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 492.0
TLS3_k127_7771889_9 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 389.0
TLS3_k127_7855195_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 6.39e-263 818.0
TLS3_k127_7855195_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.702e-259 802.0
TLS3_k127_7855195_10 response regulator receiver K07688,K07690 - - 0.00000000000000000000000000000000000000000000000005734 181.0
TLS3_k127_7855195_12 - - - - 0.00003602 48.0
TLS3_k127_7855195_14 PilZ domain - - - 0.0006003 48.0
TLS3_k127_7855195_2 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 521.0
TLS3_k127_7855195_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 467.0
TLS3_k127_7855195_4 abc transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 434.0
TLS3_k127_7855195_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 365.0
TLS3_k127_7855195_6 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 347.0
TLS3_k127_7855195_7 Phosphoglucose isomerase K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 287.0
TLS3_k127_7855195_8 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 288.0
TLS3_k127_7855195_9 Thioredoxin K03671 - - 0.0000000000000000000000000000000000000000000000000000000000000287 214.0
TLS3_k127_7873381_0 Glycosyl hydrolase family 57 - - - 6.929e-294 909.0
TLS3_k127_7873381_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 585.0
TLS3_k127_7873381_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000001091 174.0
TLS3_k127_788269_0 Pilus assembly protein K12279 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 378.0
TLS3_k127_788269_1 Domain of unknown function DUF11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 387.0
TLS3_k127_788269_10 domain, Protein K02014,K16087 - - 0.00000000000000000000000002262 128.0
TLS3_k127_788269_11 general secretion pathway protein K02458,K10924,K10925 - - 0.000000000000000000106 94.0
TLS3_k127_788269_12 Tfp pilus assembly protein FimT K10926 - - 0.000000000000000642 87.0
TLS3_k127_788269_14 PFAM SMP-30 Gluconolaconase - - - 0.00000000017 76.0
TLS3_k127_788269_2 Prokaryotic N-terminal methylation motif K12285 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007996 270.0
TLS3_k127_788269_3 Fimbrial assembly protein (PilN) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006599 252.0
TLS3_k127_788269_4 carbon utilization K12280 - - 0.0000000000000000000000000000000000000000000000000000000000000000003363 237.0
TLS3_k127_788269_5 alginic acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000002486 241.0
TLS3_k127_788269_6 - - - - 0.000000000000000000000000000000000000000000000000000000002989 206.0
TLS3_k127_788269_7 general secretion pathway protein K02456,K02457,K02458,K10930,K12285 - - 0.00000000000000000000000000000000000000000000000000001493 192.0
TLS3_k127_788269_8 type IV pilus modification protein PilV K10927 - - 0.00000000000000000000000000000000000001026 149.0
TLS3_k127_788269_9 Pilus assembly protein PilX - - - 0.00000000000000000000000000002368 123.0
TLS3_k127_7921446_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1600.0
TLS3_k127_7921446_1 Protein of unknown function - - - 0.0 1533.0
TLS3_k127_7921446_10 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 7.361e-196 616.0
TLS3_k127_7921446_11 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 575.0
TLS3_k127_7921446_12 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006949 514.0
TLS3_k127_7921446_13 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 514.0
TLS3_k127_7921446_14 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 507.0
TLS3_k127_7921446_15 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 473.0
TLS3_k127_7921446_16 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 472.0
TLS3_k127_7921446_17 PFAM type IV pilus assembly PilZ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 354.0
TLS3_k127_7921446_18 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 348.0
TLS3_k127_7921446_19 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000353 258.0
TLS3_k127_7921446_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1513.0
TLS3_k127_7921446_20 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000004479 256.0
TLS3_k127_7921446_21 Competence-damaged protein K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000001166 236.0
TLS3_k127_7921446_22 Colicin V production protein K03558 - - 0.00000000000000000000000000000000000000000000000000000000004644 212.0
TLS3_k127_7921446_23 RecX family K03565 - - 0.0000000000000000000000000000000000000000000000000000000006921 206.0
TLS3_k127_7921446_24 - - - - 0.000000000000000000000000000000000000000000000000000001468 196.0
TLS3_k127_7921446_25 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000007383 179.0
TLS3_k127_7921446_26 Sporulation related domain K03749 - - 0.0000000000000000000000000000000000006063 147.0
TLS3_k127_7921446_27 AI-2E family transporter - - - 0.00000000000000000000000002846 123.0
TLS3_k127_7921446_28 Zinc-finger domain - - - 0.0000000000000000000000000405 112.0
TLS3_k127_7921446_29 phosphorelay signal transduction system - - - 0.0000000000000000000000002734 110.0
TLS3_k127_7921446_3 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1280.0
TLS3_k127_7921446_30 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000000000002298 99.0
TLS3_k127_7921446_31 Domain of unknown function (DUF4160) - - - 0.00000000000000000002765 93.0
TLS3_k127_7921446_32 - - - - 0.00000000000000003935 82.0
TLS3_k127_7921446_33 Protein of unknown function (DUF2442) - - - 0.0000000000000002978 81.0
TLS3_k127_7921446_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.114e-284 878.0
TLS3_k127_7921446_5 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 1.064e-277 860.0
TLS3_k127_7921446_6 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 6.828e-246 765.0
TLS3_k127_7921446_7 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 6.076e-226 703.0
TLS3_k127_7921446_8 PFAM Mur ligase middle domain protein K11754 - 6.3.2.12,6.3.2.17 2.291e-203 644.0
TLS3_k127_7921446_9 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase K01769 - 4.6.1.2 5.367e-197 626.0
TLS3_k127_7936387_0 Putative diguanylate phosphodiesterase - - - 1.779e-258 814.0
TLS3_k127_7936387_1 PFAM permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 563.0
TLS3_k127_7936387_10 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000001502 145.0
TLS3_k127_7936387_11 Thioredoxin domain - - - 0.00000000000000000000000000000000002291 139.0
TLS3_k127_7936387_12 Hemerythrin-like metal-binding protein - - - 0.00000000000000000007552 95.0
TLS3_k127_7936387_13 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.0000000009086 66.0
TLS3_k127_7936387_2 Two component transcriptional regulator PhoB, winged helix family K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 357.0
TLS3_k127_7936387_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 363.0
TLS3_k127_7936387_4 SMART Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000374 263.0
TLS3_k127_7936387_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001832 235.0
TLS3_k127_7936387_6 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000003289 232.0
TLS3_k127_7936387_7 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000000000000000007811 173.0
TLS3_k127_7936387_8 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000001078 171.0
TLS3_k127_7936387_9 PFAM porin Gram-negative type - - - 0.0000000000000000000000000000000000000000000001377 172.0
TLS3_k127_7949228_0 Citrate transporter - - - 3.262e-208 656.0
TLS3_k127_7949228_1 Domain of unknown function DUF21 K03699 - - 0.000000000000000000000000000000000000000000000000000000000008797 209.0
TLS3_k127_7950575_0 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 3.997e-219 694.0
TLS3_k127_7950575_1 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 450.0
TLS3_k127_7950575_2 Belongs to the heme-copper respiratory oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004034 256.0
TLS3_k127_7950575_3 Invasion gene expression up-regulator, SirB - - - 0.0000000000000000000000000000000000000008231 152.0
TLS3_k127_7950575_4 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000002723 146.0
TLS3_k127_7950575_5 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000007697 114.0
TLS3_k127_7950575_6 sulfur carrier activity K08363 - - 0.00000000000006698 75.0
TLS3_k127_7955115_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01955 - 6.3.5.5 0.0 1137.0
TLS3_k127_7955115_1 PFAM thiamine pyrophosphate K01652 - 2.2.1.6 0.0 1014.0
TLS3_k127_7955115_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 1.468e-212 664.0
TLS3_k127_7955115_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 1.735e-212 661.0
TLS3_k127_7955115_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 428.0
TLS3_k127_7955115_5 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 363.0
TLS3_k127_7955115_6 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 339.0
TLS3_k127_7955115_7 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000002414 263.0
TLS3_k127_7955115_8 Protein of unknown function (DUF1566) - - - 0.0000000000000000000000000000005722 130.0
TLS3_k127_7955115_9 PFAM Cytochrome c, class I K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000001623 102.0
TLS3_k127_8000988_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 2.192e-287 884.0
TLS3_k127_8000988_1 Peptidase family U32 C-terminal domain K08303 - - 4.257e-197 624.0
TLS3_k127_8000988_2 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 462.0
TLS3_k127_8000988_3 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000000000000000000000000000112 177.0
TLS3_k127_8039173_0 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.0 1690.0
TLS3_k127_8039173_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1139.0
TLS3_k127_8039173_10 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 347.0
TLS3_k127_8039173_11 2Fe-2S iron-sulfur cluster binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 342.0
TLS3_k127_8039173_12 Part of a membrane complex involved in electron transport K03612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 333.0
TLS3_k127_8039173_13 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 299.0
TLS3_k127_8039173_14 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000003731 200.0
TLS3_k127_8039173_15 Positive regulator of sigma(E), RseC/MucC K03803 - - 0.00000000000000000000000000000000000000000000000001791 188.0
TLS3_k127_8039173_16 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000003112 171.0
TLS3_k127_8039173_17 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000000000000000000000000000003752 144.0
TLS3_k127_8039173_18 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000001454 127.0
TLS3_k127_8039173_19 4Fe-4S binding domain K00176 - 1.2.7.3 0.00000000000000000000000000002035 119.0
TLS3_k127_8039173_2 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239,K00278 - 1.3.5.1,1.3.5.4,1.4.3.16 8.699e-273 848.0
TLS3_k127_8039173_3 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily K03615 - - 3.996e-247 771.0
TLS3_k127_8039173_4 Part of a membrane complex involved in electron transport K03614 - - 2.771e-198 622.0
TLS3_k127_8039173_5 oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 8.328e-195 614.0
TLS3_k127_8039173_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 554.0
TLS3_k127_8039173_7 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 456.0
TLS3_k127_8039173_8 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 399.0
TLS3_k127_8039173_9 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 379.0
TLS3_k127_8093695_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 9.867e-248 769.0
TLS3_k127_8093695_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 7.104e-229 711.0
TLS3_k127_8093695_2 DAHP synthetase I family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 506.0
TLS3_k127_8093695_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 496.0
TLS3_k127_8093695_4 Subtilase family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009605 484.0
TLS3_k127_8093695_5 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 343.0
TLS3_k127_8093695_6 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 340.0
TLS3_k127_8093695_7 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 332.0
TLS3_k127_8093695_8 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000000000000000006948 150.0
TLS3_k127_814200_0 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.0 1212.0
TLS3_k127_814200_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 582.0
TLS3_k127_814200_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 575.0
TLS3_k127_814200_3 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 544.0
TLS3_k127_814200_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 309.0
TLS3_k127_814200_5 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002848 281.0
TLS3_k127_814200_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000000001107 168.0
TLS3_k127_8158955_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 6.3e-321 990.0
TLS3_k127_8158955_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009614 600.0
TLS3_k127_8158955_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 394.0
TLS3_k127_8158955_3 rod shape-determining protein MreD K03571 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001317 255.0
TLS3_k127_8158955_4 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000000000000000001547 180.0
TLS3_k127_8158955_5 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000003721 106.0
TLS3_k127_8158955_6 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000008728 84.0
TLS3_k127_8158955_7 - - - - 0.00000002623 64.0
TLS3_k127_817475_0 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005485 350.0
TLS3_k127_817475_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 333.0
TLS3_k127_817475_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000009072 251.0
TLS3_k127_817475_3 Uracil DNA glycosylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000001821 204.0
TLS3_k127_817475_4 Protein of unknown function (DUF2782) - - - 0.000000000000000000000000000000000000001137 155.0
TLS3_k127_817475_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000004763 146.0
TLS3_k127_8190266_0 Collagenase K08303 - - 5.715e-247 767.0
TLS3_k127_8190266_1 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 289.0
TLS3_k127_8190266_2 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002627 264.0
TLS3_k127_8190266_3 DJ-1/PfpI family K03152 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000001844 239.0
TLS3_k127_8190266_4 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000001478 132.0
TLS3_k127_8204763_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 567.0
TLS3_k127_8204763_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000005731 199.0
TLS3_k127_8204763_2 Protein of unknown function (DUF2288) - - - 0.00000000000000000000000000002933 128.0
TLS3_k127_8204763_3 - - - - 0.000000725 55.0
TLS3_k127_822889_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 2.082e-218 680.0
TLS3_k127_822889_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000001843 194.0
TLS3_k127_8239123_0 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009531 584.0
TLS3_k127_8239123_1 FtsJ-like methyltransferase K06968 - 2.1.1.186 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009137 567.0
TLS3_k127_8239123_2 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 526.0
TLS3_k127_8239123_3 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 347.0
TLS3_k127_8239123_4 Transposase and inactivated derivatives - - - 0.0009687 42.0
TLS3_k127_8242815_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 9.912e-202 631.0
TLS3_k127_8242815_1 UbiA prenyltransferase family K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 419.0
TLS3_k127_8242815_2 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 397.0
TLS3_k127_8242815_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 304.0
TLS3_k127_8242815_4 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000001022 171.0
TLS3_k127_8242815_5 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000001035 135.0
TLS3_k127_8292947_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.769e-205 641.0
TLS3_k127_8292947_1 Sensory box GGDEF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 568.0
TLS3_k127_8292947_2 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 441.0
TLS3_k127_8292947_3 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 339.0
TLS3_k127_8292947_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 351.0
TLS3_k127_8292947_5 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 321.0
TLS3_k127_8292947_6 Sigma factor PP2C-like phosphatases K20977 - - 0.00000000000000000000000000000000000000000000000000000774 207.0
TLS3_k127_8292947_7 Methyl-accepting chemotaxis protein (MCP) signalling domain - - - 0.0000000000000000000000000000000000000000003645 179.0
TLS3_k127_8292947_8 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000000000000164 138.0
TLS3_k127_8292947_9 Regulatory protein, FmdB family - - - 0.00000000000000000000000000000007383 126.0
TLS3_k127_8387820_0 Histidine Phosphotransfer domain K02487,K06596 - - 0.0 1239.0
TLS3_k127_8387820_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 3.924e-251 784.0
TLS3_k127_8387820_10 PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 345.0
TLS3_k127_8387820_11 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 312.0
TLS3_k127_8387820_12 cheY-homologous receiver domain K02657 - - 0.0000000000000000000000000000000000000000000000000000000121 201.0
TLS3_k127_8387820_13 Two component signalling adaptor domain K02659 - - 0.00000000000000000000000000000000000000000000000009231 189.0
TLS3_k127_8387820_14 Tautomerase enzyme K01821 - 5.3.2.6 0.0000000000000000000000000001017 115.0
TLS3_k127_8387820_2 PFAM TrkA-N domain protein K03499 - - 2.734e-249 775.0
TLS3_k127_8387820_3 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 2.282e-240 747.0
TLS3_k127_8387820_4 TIGRFAM fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 5.018e-207 646.0
TLS3_k127_8387820_5 histidine kinase HAMP region domain protein K02660,K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 584.0
TLS3_k127_8387820_6 Inositol monophosphatase family K01082,K01092 - 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 417.0
TLS3_k127_8387820_7 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 391.0
TLS3_k127_8387820_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 358.0
TLS3_k127_8387820_9 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 357.0
TLS3_k127_8462848_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1500.0
TLS3_k127_8462848_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 8.218e-213 666.0
TLS3_k127_8462848_2 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003879 266.0
TLS3_k127_8462848_3 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001916 238.0
TLS3_k127_8507025_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 7.18e-277 861.0
TLS3_k127_8507025_1 receptor K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 458.0
TLS3_k127_8507025_2 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009154 278.0
TLS3_k127_8507025_3 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000256 274.0
TLS3_k127_8507025_4 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008203 243.0
TLS3_k127_8507025_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000002738 212.0
TLS3_k127_8507025_6 - - - - 0.0000000000000000000000000000000000000000001324 166.0
TLS3_k127_8507025_7 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000000000000000000000000000349 162.0
TLS3_k127_8507025_8 Cell division protein ZapA K09888 - - 0.0000000000000000000000000000000000000000005666 158.0
TLS3_k127_8507025_9 - - - - 0.000000000000002484 78.0
TLS3_k127_8510483_0 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 1.317e-273 865.0
TLS3_k127_8510483_1 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 4.194e-228 713.0
TLS3_k127_8510483_2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 512.0
TLS3_k127_8510483_3 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 415.0
TLS3_k127_8510483_4 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 417.0
TLS3_k127_8510483_5 Inhibitor of apoptosis-promoting Bax1 K19416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 368.0
TLS3_k127_8510483_6 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004056 274.0
TLS3_k127_8510483_7 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004541 258.0
TLS3_k127_8510483_8 Winged helix-turn helix - - - 0.000000008543 56.0
TLS3_k127_8552561_0 response regulator receiver K10126,K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 555.0
TLS3_k127_8552561_1 pyridine nucleotide-disulfide oxidoreductase family protein K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 494.0
TLS3_k127_8552561_2 Phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 456.0
TLS3_k127_8552561_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007552 419.0
TLS3_k127_8552561_4 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 388.0
TLS3_k127_8552561_5 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003692 254.0
TLS3_k127_8552561_6 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000002502 233.0
TLS3_k127_8552561_7 - - - - 0.00000000000000000000000000000002045 134.0
TLS3_k127_8552561_8 Peptide methionine sulfoxide reductase - - - 0.0000000001216 64.0
TLS3_k127_8586737_0 TIGRFAM heavy metal efflux pump, CzcA family K07787 - - 0.0 1034.0
TLS3_k127_8586737_1 Predicted membrane protein (DUF2231) - - - 0.0000000000000000000000000000000000000000000000000000000000000007944 223.0
TLS3_k127_8586737_2 - - - - 0.0000000000000000000000000000002517 130.0
TLS3_k127_8586737_3 membrane protein (DUF2078) K08982 - - 0.000009229 49.0
TLS3_k127_8586737_4 ABC-type transport auxiliary lipoprotein component K09857 - - 0.0005016 42.0
TLS3_k127_877459_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1054.0
TLS3_k127_877459_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 2.587e-239 744.0
TLS3_k127_877459_10 response regulator K11444 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 340.0
TLS3_k127_877459_11 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 353.0
TLS3_k127_877459_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 333.0
TLS3_k127_877459_13 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 318.0
TLS3_k127_877459_14 Methylase of chemotaxis methyl-accepting K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 327.0
TLS3_k127_877459_15 Chemotaxis signal transduction protein K03408 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 291.0
TLS3_k127_877459_16 PFAM histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008116 293.0
TLS3_k127_877459_17 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001708 271.0
TLS3_k127_877459_18 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001037 274.0
TLS3_k127_877459_19 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000006121 247.0
TLS3_k127_877459_2 Phospholipase D. Active site motifs. K06131 - - 6.584e-235 736.0
TLS3_k127_877459_20 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000009345 225.0
TLS3_k127_877459_21 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000001397 207.0
TLS3_k127_877459_22 response regulator K11444 - 2.7.7.65 0.000000000000000000000000000000000000000000000001136 198.0
TLS3_k127_877459_23 PFAM S23 ribosomal protein - - - 0.000000000000000000000000000000000000008367 147.0
TLS3_k127_877459_24 Ferredoxin - - - 0.00000000000000000000000000000000000002122 145.0
TLS3_k127_877459_25 Transcriptional regulator - - - 0.00000000000000000000000000001254 120.0
TLS3_k127_877459_26 protein phosphatase 2C domain protein - - - 0.00000000002854 73.0
TLS3_k127_877459_27 - K14340 - - 0.000000004466 69.0
TLS3_k127_877459_28 GtrA family - - - 0.000004938 54.0
TLS3_k127_877459_29 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00009277 45.0
TLS3_k127_877459_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03407 - 2.7.13.3 4.102e-219 702.0
TLS3_k127_877459_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 566.0
TLS3_k127_877459_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 522.0
TLS3_k127_877459_6 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 466.0
TLS3_k127_877459_7 signal peptide protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 389.0
TLS3_k127_877459_8 CheB methylesterase K03412,K13491 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 366.0
TLS3_k127_877459_9 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 331.0
TLS3_k127_896483_0 ABC transporter C-terminal domain K15738 - - 0.0 1049.0
TLS3_k127_896483_1 Neisseria PilC beta-propeller domain K02674 - - 8.325e-285 925.0
TLS3_k127_896483_10 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000006108 241.0
TLS3_k127_896483_11 type IV pilus modification protein PilV - - - 0.0000000000000000000000000000000000000000000000000000000000000002864 226.0
TLS3_k127_896483_12 Pilus assembly protein PilX - - - 0.00000000000000000000000000000000000000000003066 169.0
TLS3_k127_896483_13 Protein of unknown function (DUF454) K09790 - - 0.0000000000000000000000000000000000000004381 153.0
TLS3_k127_896483_14 COG4968 Tfp pilus assembly protein PilE K02655 - - 0.0000000000000000000000000000000000002615 145.0
TLS3_k127_896483_15 protein transport across the cell outer membrane K08084 - - 0.0000000000000000000000008213 110.0
TLS3_k127_896483_17 - - - - 0.00001262 49.0
TLS3_k127_896483_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 6.244e-213 668.0
TLS3_k127_896483_3 ABC transporter transmembrane region K12541 - - 1.053e-207 659.0
TLS3_k127_896483_4 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 599.0
TLS3_k127_896483_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006311 495.0
TLS3_k127_896483_6 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 342.0
TLS3_k127_896483_7 Type IV Pilus-assembly protein W K02672 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 332.0
TLS3_k127_896483_8 Protein of unknown function (DUF3617) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008373 288.0
TLS3_k127_896483_9 Belongs to the peptidase S11 family K01286,K07258,K07262 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000812 259.0
TLS3_k127_906162_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1405.0
TLS3_k127_906162_1 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 594.0
TLS3_k127_906162_10 - - - - 0.00000000000000000000000007349 109.0
TLS3_k127_906162_11 BRO family, N-terminal domain - - - 0.0000000000000008973 82.0
TLS3_k127_906162_12 Transcriptional regulator K13643 - - 0.00000000000319 66.0
TLS3_k127_906162_2 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 483.0
TLS3_k127_906162_3 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 458.0
TLS3_k127_906162_4 Plasmid maintenance system antidote protein K18831 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 380.0
TLS3_k127_906162_5 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 370.0
TLS3_k127_906162_6 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 361.0
TLS3_k127_906162_7 - - - - 0.000000000000000000000000000000000000000000000000000000001741 204.0
TLS3_k127_906162_8 Pfam Plasmid maintenance system killer K07334 - - 0.00000000000000000000000000000009122 126.0
TLS3_k127_906162_9 BRO family, N-terminal domain - - - 0.00000000000000000000000000002471 119.0
TLS3_k127_919136_0 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 9.314e-249 805.0
TLS3_k127_919136_1 Thiolase, C-terminal domain K00632 - 2.3.1.16 6.91e-219 683.0
TLS3_k127_919136_10 - - - - 0.00000000000000000000000000000000000001326 164.0
TLS3_k127_919136_11 - - - - 0.00000000000000000000000000000000000005601 163.0
TLS3_k127_919136_12 - - - - 0.00000000000000000000000000000000000008726 144.0
TLS3_k127_919136_13 - - - - 0.00000000000000000000000000000000004792 156.0
TLS3_k127_919136_14 Putative quorum-sensing-regulated virulence factor K09954 - - 0.0000000000000000000000000000000002029 132.0
TLS3_k127_919136_15 dienelactone hydrolase - - - 0.000000000000000000000000000000003291 147.0
TLS3_k127_919136_16 domain protein - - - 0.0000000000000000000000000006999 130.0
TLS3_k127_919136_17 transferase activity, transferring glycosyl groups K20276 - - 0.00000000000000000009649 104.0
TLS3_k127_919136_18 cellulose binding K01179 - 3.2.1.4 0.00000000000000000073 102.0
TLS3_k127_919136_19 - - - - 0.000000000000008782 74.0
TLS3_k127_919136_2 FecR protein - - - 1.453e-212 702.0
TLS3_k127_919136_20 ORF6N domain - - - 0.000000000003173 72.0
TLS3_k127_919136_21 Subtilase family - - - 0.00000000002801 77.0
TLS3_k127_919136_22 cAMP phosphodiesterases class-II - - - 0.00000000002823 68.0
TLS3_k127_919136_23 - - - - 0.00000000003115 64.0
TLS3_k127_919136_24 serine-type endopeptidase activity - - - 0.0005265 51.0
TLS3_k127_919136_3 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 629.0
TLS3_k127_919136_4 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 504.0
TLS3_k127_919136_5 Adenylate cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 461.0
TLS3_k127_919136_6 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 348.0
TLS3_k127_919136_7 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000000000000000000000000000000000004369 236.0
TLS3_k127_919136_8 - - - - 0.0000000000000000000000000000000000000000006401 178.0
TLS3_k127_919136_9 Uncharacterized ACR, COG1993 - - - 0.0000000000000000000000000000000000000001975 153.0
TLS3_k127_922770_0 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 442.0
TLS3_k127_922770_1 TIGRFAM decaheme c-type cytochrome, DmsE family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 369.0
TLS3_k127_922770_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 352.0
TLS3_k127_922770_3 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 333.0
TLS3_k127_922770_4 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000123 310.0
TLS3_k127_922770_5 cytochrome c-type protein K02569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001345 256.0
TLS3_k127_922770_6 Pfam cytochrome c K17230 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003604 246.0
TLS3_k127_922770_7 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07660 - - 0.0000000000000000000000000000000000000000000000000001836 194.0
TLS3_k127_922770_8 - - - - 0.000000000000000000000000000000000000000001211 161.0
TLS3_k127_922770_9 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000008838 105.0
TLS3_k127_94763_0 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008612 331.0
TLS3_k127_94763_1 Intracellular septation protein A K06190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009023 298.0
TLS3_k127_94763_2 Belongs to the MsrB Met sulfoxide reductase family K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000001439 208.0
TLS3_k127_94763_3 YCII-related domain K09780 - - 0.0000000000000000000000000000000000000006716 161.0
TLS3_k127_95766_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.421e-299 931.0
TLS3_k127_95766_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.432e-233 729.0
TLS3_k127_95766_10 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 407.0
TLS3_k127_95766_11 SMART metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 358.0
TLS3_k127_95766_12 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 346.0
TLS3_k127_95766_13 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 341.0
TLS3_k127_95766_14 response regulator, receiver K07315,K20977 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 319.0
TLS3_k127_95766_15 Bacterial regulatory protein, Fis family K15012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009085 273.0
TLS3_k127_95766_16 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000001276 205.0
TLS3_k127_95766_17 Chemoreceptor zinc-binding domain - - - 0.00000000000000000000000000000000002391 139.0
TLS3_k127_95766_18 Protein of unknown function (DUF493) K09158 - - 0.00000000000000000000000000000006509 126.0
TLS3_k127_95766_19 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000004114 107.0
TLS3_k127_95766_2 Histidine kinase A domain protein - - - 7.253e-220 751.0
TLS3_k127_95766_3 PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009126 569.0
TLS3_k127_95766_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 566.0
TLS3_k127_95766_5 PFAM ATP-binding region ATPase domain protein K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 562.0
TLS3_k127_95766_6 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 486.0
TLS3_k127_95766_7 PFAM aminotransferase class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 467.0
TLS3_k127_95766_8 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 449.0
TLS3_k127_95766_9 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 437.0
TLS3_k127_962740_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 7.056e-218 679.0
TLS3_k127_962740_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 2.273e-197 618.0
TLS3_k127_962740_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 606.0
TLS3_k127_962740_3 pilus assembly protein FimV K08086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 614.0
TLS3_k127_962740_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 408.0
TLS3_k127_962740_5 response to toxic substance K16347,K16348 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000114 56.0
TLS3_k127_98142_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1461.0
TLS3_k127_98142_1 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 391.0
TLS3_k127_98142_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 364.0
TLS3_k127_98142_3 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 346.0
TLS3_k127_98142_4 crp fnr family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 343.0
TLS3_k127_98142_5 Glycoprotease family K14742 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 311.0
TLS3_k127_98142_6 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000003327 265.0
TLS3_k127_98142_7 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000001659 194.0
TLS3_k127_993931_0 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 2.769e-219 681.0
TLS3_k127_993931_1 Glycosyl transferase family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 569.0
TLS3_k127_993931_10 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000008245 178.0
TLS3_k127_993931_2 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 531.0
TLS3_k127_993931_3 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 509.0
TLS3_k127_993931_4 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 475.0
TLS3_k127_993931_5 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 394.0
TLS3_k127_993931_6 SMART ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 376.0
TLS3_k127_993931_7 photoreceptor activity K02007,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002784 300.0
TLS3_k127_993931_8 response regulator K02485 - - 0.000000000000000000000000000000000000000000000000000000000000000006595 227.0
TLS3_k127_993931_9 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000005713 230.0